Cynthia B. Paschal, Ph.D.

Associate Professor
Faculty Appointments
Senior Associate Dean for Undergraduate Education Associate Professor of Biomedical Engineering Associate Professor of Radiology and Radiological Sciences
Ph.D., Biomedical Engineering, Case Western Reserve University, Cleveland, OhioS.M., Biomedical Engineerng, Massachusetts Institute of Technology, Cambridge, MassachusettsS.B., Biomedical Engineerng, Massachusetts Institute of Technology, Cambridge, Massachusetts
Office Address
5332 Stevenson Center
Nashville, TN 37235
Research Description
Development of magnetic resonance imaging (MRI) techniques and applications for the study of cardiopulmonary diseases, especially to create quantitative non-invasive pulmonary angiograms and to characterize and quantify pulmonary edema and other lung pathologies and to characterize infarcted and normal myocardium; use of laser printers for x-ray image output; and methods of imaging education.
Research Keywords
Medical imaging: magnetic resonance imaging, computed tomography
Clinical Research Keywords
Magnetic resonance angiography Cardiopulmonary magnetic resonance imaging
Cobb JG, Paschal CB. Improved in vivo measurement of myocardial transverse relaxation with 3 Tesla magnetic resonance imaging. J Magn Reson Imaging. 2009 Sep; 30(3): 684-9. PMID: 19711419, PMCID: PMC2868375, DOI: 10.1002/jmri.21877, ISSN: 1053-1807.

Anderson DJ, Dendy JM, Paschal CB. Simulation study of susceptibility gradients leading to focal myocardial signal loss. J Magn Reson Imaging. 2008 Dec; 28(6): 1402-8. PMID: 19025948, PMCID: PMC2987697, DOI: 10.1002/jmri.21619, ISSN: 1053-1807.

Nichols MB, Paschal CB. Measurement of longitudinal (T1) relaxation in the human lung at 3.0 Tesla with tissue-based and regional gradient analyses. J Magn Reson Imaging. 2008 Jan; 27(1): 224-8. PMID: 18058926, DOI: 10.1002/jmri.21243, ISSN: 1053-1807.

Paschal CB, Nightingale KR, Ropella KM. Undergraduate biomedical imaging education. Ann Biomed Eng [print-electronic]. 2006 Feb; 34(2): 232-8. PMID: 16450191, DOI: 10.1007/s10439-005-9031-2, ISSN: 0090-6964.

Cynthia B. Paschal, Kathy R. Nightingale, Kristina M. Ropella. Undergraduate Biomedical Imaging Education. Annals of Biomedical Engineering. 2006; 2((34)): 232-8.

Paschal CB, Morris HD. K-space in the clinic. J Magn Reson Imaging. 2004 Feb; 19(2): 145-59. PMID: 14745747, DOI: 10.1002/jmri.10451, ISSN: 1053-1807.

D.A.Yoder, Y. Zhao, C.B. Paschal, and J.M. Fitzpatrick. MRI simulator with object-specific field map calculation. Magnetic Resonance Imaging. 2004; 22((3)): 315-28.

Paschal CB. The need for effective biomedical imaging education. IEEE Eng Med Biol Mag. 2003 Jul; 22(4): 88-91. PMID: 14515698, ISSN: 0739-5175.

Paschal CB. Formative assessment in physiology teaching using a wireless classroom communication system. Adv Physiol Educ. 2002 Dec; 26(1-4): 299-308. PMID: 12444002, ISSN: 1043-4046.

C.B. Paschal. Formative Assessment in Physiology Teaching Using A Wireless Communication System. Advances in Physiology Education. 2002.

J.D. Nguyen*, C.B. Paschal. Development Of Online Ultrasound Instructional Module And Comparison To Traditional Teaching Methods. Journal of Engineering Education. 2002; 91((3)): 275-83.

Amorino GP, Lee H, Holburn GE, Paschal CB, Hercules SK, Shyr Y, Steffen RP, Choy H. Enhancement of tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13. Radiat. Res. 2001 Sep; 156(3): 294-300. PMID: 11500138, ISSN: 0033-7587.

S.S. Halliburton*, C.B. Paschal, J.D. Rothpletz, J.E. Loyd. Estimation and Visualization of Regional and Global Pulmonary Perfusion with 3D Magnetic Resonance Angiography. Journal of Magnetic Resonance Imaging. 2001; 14((6)): 734-40.

G.P. Amorino, H. Lee, G.E. Holburn, C.B. Paschal, S.K. Hercules, Y. Shyr, R.P. Steffen, H.Choy. Enhancement of Tumor Oxygenation and Radiation Response by the Allosteric Effector of Hemoglobin, RSR13. Radiation Research. 2001; 156: 294-300.

Halliburton SS, Paschal CB, Rothpletz JD. Evaluation of radiofrequency pulses and contrast agent doses for use in 3D pulmonary magnetic resonance angiography. J Magn Reson Imaging. 1999 Dec; 10(6): 929-38. PMID: 10581505, PII: 10.1002/(SICI)1522-2586(199912)10:6<929::AID-JMRI4>3.0.CO;2-Q, ISSN: 1053-1807.

Friedli JL, Paschal CB, Loyd JE, Halliburton SS. Quantitative 3D VUSE pulmonary MRA. Magn Reson Imaging. 1999 Apr; 17(3): 363-70. PMID: 10195579, PII: S0730725X98001775, ISSN: 0730-725X.

A. Priatna*, C.B. Paschal, R.G. Shiavi. Evaluation of Linear Diaphragm-Chest Expansion Models for Magnetic. 1999.

J.L. Friedli*, C.B. Paschal, J.E. Loyd, S. S. Halliburton*. Quantitative 3D VUSE Pulmonary MRA. 1999.

S.S. Halliburton*, C.B. Paschal, J. Rothpletz, J.E. Loyd. Evaluation of Radiofrequency Pulses and Contrast Agent Doses for use in 3D Pulmonary MR Angiography. 1999.

Stefansic JD, Paschal CB. Effects of acceleration, jerk, and field inhomogeneities on vessel positions in magnetic resonance angiography. Magn Reson Med. 1998 Aug; 40(2): 261-71. PMID: 9702708, ISSN: 0740-3194.

Caruthers SD, Paschal CB, Pou NA, Roselli RJ, Harris TR. Regional measurements of pulmonary edema by using magnetic resonance imaging. J. Appl. Physiol. 1998 Jun; 84(6): 2143-53. PMID: 9609811, ISSN: 8750-7587.

J.D. Stefansic* and C.B. Paschal. Effects of Acceleration, Jerk, and Field Inhomogeneities on Vessel Positions in Magnetic Resonance Angiography. 1998.

S.D. Caruthers*, C.B. Paschal, N.A. Pou, R.J. Roselli, T.R. Harris. Regional Measurements of Pulmonary Edema using Magnetic Resonance Imaging. 1998.

Caruthers SD, Paschal CB, Pou NA, Harris TR. Relative quantification of pulmonary edema with noncontrast-enhanced MRI. J Magn Reson Imaging. 1997 May; 7(3): 544-50. PMID: 9170040, ISSN: 1053-1807.

Friedli JL, Paschal CB. Evaluation of variable-angle uniform signal excitation, tilted optimized nonsaturating excitation, and flat radio-frequency pulses in free-breathing non-contrast-enhanced pulmonary MR angiography. Radiology. 1997 Mar; 202(3): 863-7. PMID: 9051047, DOI: 10.1148/radiology.202.3.9051047, ISSN: 0033-8419.

S.D. Caruthers*, C.B. Paschal, N.A. Pou, T.R. Harris. Relative Quantification of Pulmonary Edema with Non-contrast Enhanced MRI. 1997.

J.L. Friedli* and C.B. Paschal. Evaluation of Variable-Angle Uniform Signal Excitation, Tilted Optimized Nonsaturating Excitation, and Flat Radiofrequency Pulses in Free-Breathing Non-Contrast Enhanced Pulmonary MR Angiography. Radiology. 1997; 202: 863-7.

Halliburton SS, Paschal CB. Atherosclerotic plaque components in human aortas contrasted by ex vivo imaging using fast spin-echo magnetic resonance imaging and spiral computed tomography. Invest Radiol. 1996 Nov; 31(11): 724-8. PMID: 8915754, ISSN: 0020-9996.

Schreiner S, Paschal CB, Galloway RL. Comparison of projection algorithms used for the construction of maximum intensity projection images. J Comput Assist Tomogr. 1996 Jan; 20(1): 56-67. PMID: 8576483, ISSN: 0363-8715.

Schreiner S, Dawant BM, Paschal CB, Galloway RL. The importance of ray pathlengths when measuring objects in maximum intensity projection images. IEEE Trans Med Imaging. 1996; 15(4): 568-79. PMID: 18215938, DOI: 10.1109/42.511760, ISSN: 0278-0062.

S. Schreiner*, B.M. Dawant, C.B. Paschal, R.L. Galloway. The Importance of Ray Pathlengths when Measuring Objects in Maximum Intensity Projection Images. IEEE Transactions on Medical Imaging. 1996; 15((4)): 568-78.

S. Schreiner*, C.B. Paschal, R.L. Galloway. Comparison of Projection Algorithms Used for the Construction of Maximum Intensity Projection Images. Journal of Computer Assisted Tomography. 1996; 20((1)): 56-67.

S.S. Halliburton* and C.B. Paschal. Atherosclerotic Plaque Components in Human Aortas Contrasted by Ex Vivo Imaging Using Fast Spin-Echo Magnetic Resonance Imaging and Spiral Computed Tomography. Investigative Radiology. 1996; 31((11)): 724-8.

Priatna A, Paschal CB. Variable-angle uniform signal excitation (VUSE) for three-dimensional time-of-flight MR angiography. J Magn Reson Imaging. 1995 Jul; 5(4): 421-7. PMID: 7549204, ISSN: 1053-1807.

M.B.M. Hofman, C.B. Paschal, D. Li, E.M. Haacke, A.C. van Rossum, M. Sprenger. MRI of Coronary Arteries: 2D Breath-Hold versus 3D Respiratory-Gated Acquisition. J. Computer Assist. Tomography. 1995; 19((1)): 56-62.

A. Priatna* and C.B. Paschal. Variable-Angle Uniform Signal Excitation (VUSE) for Three-Dimensional Time-of-Flight MR Angiography. Journal of Magnetic Resonance Imaging. 1995; 5((4)): 421-7.

C.B. Paschal, E.M. Haacke, L.P. Adler. Three-dimensional MR Imaging of the Coronary Arteries: Preliminary Clinical Experienc. J. Magnetic Resonance Imaging. 1993; 3: 491-500.

Debiao Li, Cynthia B. Paschal, E. Mark Haacke, Lee P. Adler. Coronary Arteries: Three-Dimensional MR Imaging with Fat Saturation and Magnetization Transfer Contrast. Radiology. 1993; 187: 401-6.

C.B. Paschal, E.M. Haacke, L.P. Adler, D.A. Finelli, Magnetic Resonance Coronary Artery Imaging. CardioVascular and Interventional Radiology. 1992; 15((1)): 23-31.

R.D. White, C.B. Paschal, M.E. Clampitt, T.A. Spraggins, G.W. Lenz. ECG-Independent, 'Wireless' Cardiovascular Cine MR Imaging. J. Magnetic Resonance Imaging. 1991; 1: 347-55.