David W. Wright, Ph.D.



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Faculty Appointments
Dean of Sciences Professor of Chemistry Stevenson Chair of ChemistryProfessor of Communication of Science and Technology
Ph.D., Chemistry, Inorganic & Bioinorganic, Massachusetts Institute of Technology, Cambridge, MassachusettsB.S., Tulane University, New Orleans, LouisianaB.A., Tulane University, New Orleans, Louisiana
Office Address
VU Station B 351822
7332 Stevenson Center
Markwalter CF, Jang IK, Burton RA, Domingo GJ, Wright DW. Biolayer interferometry predicts ELISA performance of monoclonal antibody pairs for Plasmodium falciparum histidine-rich protein 2. Anal. Biochem [print-electronic]. 2017 Oct 10/1/2017; 534: 10-3. PMID: 28698001, PII: S0003-2697(17)30294-4, DOI: 10.1016/j.ab.2017.07.010, ISSN: 1096-0309.

Scherr TF, Markwalter CF, Bauer WS, Gasperino D, Wright DW, Haselton FR. Application of mass transfer theory to biomarker capture by surface functionalized magnetic beads in microcentrifuge tubes. Adv Colloid Interface Sci [print-electronic]. 2017 Aug; 246: 275-88. PMID: 28595937, PII: S0001-8686(16)30266-4, DOI: 10.1016/j.cis.2017.02.006, ISSN: 1873-3727.

Bauer WS, Kimmel DW, Adams NM, Gibson LE, Scherr TF, Richardson KA, Conrad JA, Matakala HK, Haselton FR, Wright DW. Magnetically-enabled biomarker extraction and delivery system: towards integrated ASSURED diagnostic tools. Analyst. 2017 May 5/2/2017; 142(9): 1569-80. PMID: 28386613, DOI: 10.1039/c7an00278e, ISSN: 1364-5528.

Bordelon H, Ricks KM, Pask ME, Russ PK, Solinas F, Baglia ML, Short PA, Nel A, Blackburn J, Dheda K, Zamudio C, Cáceres T, Wright DW, Haselton FR, Pettit AC. Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection. J. Microbiol. Methods [print-electronic]. 2017 May; 136: 65-70. PMID: 28285168, PMCID: PMC5421388, PII: S0167-7012(17)30050-7, DOI: 10.1016/j.mimet.2017.02.010, ISSN: 1872-8359.

Bauer WS, Richardson KA, Adams NM, Ricks KM, Gasperino DJ, Ghionea SJ, Rosen M, Nichols KP, Weigl BH, Haselton FR, Wright DW. Rapid concentration and elution of malarial antigen histidine-rich protein II using solid phase Zn(II) resin in a simple flow-through pipette tip format. Biomicrofluidics. 2017 May; 11(3): 34115. PMID: 28652885, PMCID: PMC5457299, PII: 1.4984788, PII: 020703BMF, DOI: 10.1063/1.4984788, ISSN: 1932-1058.

Scherr TF, Gupta S, Wright DW, Haselton FR. An embedded barcode for "connected" malaria rapid diagnostic tests. Lab Chip. 2017 Mar 3/29/2017; 17(7): 1314-22. PMID: 28252130, DOI: 10.1039/c6lc01580h, ISSN: 1473-0189.

Markwalter CF, Ricks KM, Bitting AL, Mudenda L, Wright DW. Simultaneous capture and sequential detection of two malarial biomarkers on magnetic microparticles. Talanta [print-electronic]. 2016 Dec 12/1/2016; 161: 443-9. PMID: 27769430, PMCID: PMC5080451, PII: S0039-9140(16)30663-4, DOI: 10.1016/j.talanta.2016.08.078, ISSN: 1873-3573.

Quiliano M, Mendoza A, Fong KY, Pabón A, Goldfarb NE, Fabing I, Vettorazzi A, López de Cerain A, Dunn BM, Garavito G, Wright DW, Deharo E, Pérez-Silanes S, Aldana I, Galiano S. Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration. Int J Parasitol Drugs Drug Resist [print-electronic]. 2016 Dec; 6(3): 184-98. PMID: 27718413, PMCID: PMC5061469, PII: S2211-3207(16)30044-6, DOI: 10.1016/j.ijpddr.2016.09.004, ISSN: 2211-3207.

Bitting AL, Bordelon H, Baglia ML, Davis KM, Creecy AE, Short PA, Albert LE, Karhade AV, Wright DW, Haselton FR, Adams NM. Automated Device for Asynchronous Extraction of RNA, DNA, or Protein Biomarkers from Surrogate Patient Samples. J Lab Autom [print-electronic]. 2016 Dec; 21(6): 732-42. PMID: 26194105, PII: 2211068215596139, DOI: 10.1177/2211068215596139, ISSN: 2211-0690.

Wong AC, Wright DW. Size-Dependent Cellular Uptake of DNA Functionalized Gold Nanoparticles. Small [print-electronic]. 2016 Oct; 12(40): 5592-600. PMID: 27562251, DOI: 10.1002/smll.201601697, ISSN: 1613-6829.

Ricks KM, Adams NM, Scherr TF, Haselton FR, Wright DW. Direct transfer of HRPII-magnetic bead complexes to malaria rapid diagnostic tests significantly improves test sensitivity. Malar. J. 2016 Aug 8/5/2016; 15(1): 399. PMID: 27495329, PMCID: PMC4975893, PII: 10.1186/s12936-016-1448-6, DOI: 10.1186/s12936-016-1448-6, ISSN: 1475-2875.

Russ PK, Karhade AV, Bitting AL, Doyle A, Solinas F, Wright DW, Haselton FR. A Prototype Biomarker Detector Combining Biomarker Extraction and Fixed Temperature PCR. J Lab Autom [print-electronic]. 2016 Aug; 21(4): 590-8. PMID: 26920577, PII: 2211068216634072, DOI: 10.1177/2211068216634072, ISSN: 2211-0690.

Scherr TF, Gupta S, Wright DW, Haselton FR. Mobile phone imaging and cloud-based analysis for standardized malaria detection and reporting. Sci Rep. 2016 Jun 6/27/2016; 6: 28645. PMID: 27345590, PMCID: PMC4921854, PII: srep28645, DOI: 10.1038/srep28645, ISSN: 2045-2322.

Gibson LE, Wright DW. Sensitive Method for Biomolecule Detection Utilizing Signal Amplification with Porphyrin Nanoparticles. Anal. Chem [print-electronic]. 2016 Jun 6/7/2016; 88(11): 5928-33. PMID: 27160976, DOI: 10.1021/acs.analchem.6b00855, ISSN: 1520-6882.

Sandlin RD, Fong KY, Stiebler R, Gulka CP, Nesbitt JE, Oliveira MP, Oliveira MF, Wright DW. Detergent-Mediated Formation of ß-Hematin: Heme Crystallization Promoted by Detergents Implicates Nanostructure Formation for Use as a Biological Mimic. Cryst Growth Des [print-electronic]. 2016 May 5/4/2016; 16(5): 2542-51. PMID: 27175104, PMCID: PMC4860678, DOI: 10.1021/acs.cgd.5b01580, ISSN: 1528-7483.

Gulka CP, Wong AC, Wright DW. Spontaneous self-assembly and disassembly of colloidal gold nanoparticles induced by tetrakis(hydroxymethyl) phosphonium chloride. Chem. Commun. (Camb.). 2016 Jan 1/21/2016; 52(6): 1266-9. PMID: 26611623, PMCID: PMC4778714, DOI: 10.1039/c5cc08211k, ISSN: 1364-548X.

Markwalter CF, Davis KM, Wright DW. Immunomagnetic capture and colorimetric detection of malarial biomarker Plasmodium falciparum lactate dehydrogenase. Anal. Biochem [print-electronic]. 2016 Jan 1/15/2016; 493: 30-4. PMID: 26475567, PII: S0003-2697(15)00480-7, DOI: 10.1016/j.ab.2015.10.003, ISSN: 1096-0309.

Jackson SR, Wong AC, Travis AR, Catrina IE, Bratu DP, Wright DW, Jayagopal A. Applications of Hairpin DNA-Functionalized Gold Nanoparticles for Imaging mRNA in Living Cells. Meth. Enzymol [print-electronic]. 2016; 572: 87-103. PMID: 27241751, PII: S0076-6879(16)00131-2, DOI: 10.1016/bs.mie.2016.03.019, ISSN: 1557-7988.

Fong KY, Sandlin RD, Wright DW. Identification of ß-hematin inhibitors in the MMV Malaria Box. Int J Parasitol Drugs Drug Resist. 2015 Dec; 5(3): 84-91. PMID: 26150923, PMCID: PMC4486462, PII: S2211-3207(15)00011-1, DOI: 10.1016/j.ijpddr.2015.05.003, ISSN: 2211-3207.

Davis KM, Bitting AL, Markwalter CF, Bauer WS, Wright DW. Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II. J Vis Exp. 2015 Jul 7/7/2015; (101): e52856. PMID: 26273845, PMCID: PMC4544453, DOI: 10.3791/52856, ISSN: 1940-087X.

Combrinck JM, Fong KY, Gibhard L, Smith PJ, Wright DW, Egan TJ. Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials. Malar. J. 2015 Jun 6/24/2015; 14: 253. PMID: 26099266, PMCID: PMC4484700, PII: 10.1186/s12936-015-0729-9, DOI: 10.1186/s12936-015-0729-9, ISSN: 1475-2875.

Gulka CP, Swartz JD, Wright DW. Ni(II)NTA AuNPs as a low-resource malarial diagnostic platform for the rapid colorimetric detection of Plasmodium falciparum Histidine-Rich Protein-2. Talanta [print-electronic]. 2015 Apr; 135: 94-101. PMID: 25640131, PII: S0039-9140(14)01030-3, DOI: 10.1016/j.talanta.2014.12.047, ISSN: 1873-3573.

Adams NM, Bordelon H, Wang KK, Albert LE, Wright DW, Haselton FR. Comparison of three magnetic bead surface functionalities for RNA extraction and detection. ACS Appl Mater Interfaces [print-electronic]. 2015 Mar 3/25/2015; 7(11): 6062-9. PMID: 25710198, DOI: 10.1021/am506374t, ISSN: 1944-8252.

Schrimpe-Rutledge AC, Fong KY, Wright DW. Impact of 4-hydroxynonenal on matrix metalloproteinase-9 regulation in lipopolysaccharide-stimulated RAW 264.7 cells. Cell Biochem. Funct [print-electronic]. 2015 Mar; 33(2): 59-66. PMID: 25663587, DOI: 10.1002/cbf.3087, ISSN: 1099-0844.

Creecy A, Russ PK, Solinas F, Wright DW, Haselton FR. Tuberculosis Biomarker Extraction and Isothermal Amplification in an Integrated Diagnostic Device. PLoS ONE. 2015; 10(7): e0130260. PMID: 26132307, PMCID: PMC4488445, PII: PONE-D-15-04914, DOI: 10.1371/journal.pone.0130260, ISSN: 1932-6203.

Sandlin RD, Fong KY, Wicht KJ, Carrell HM, Egan TJ, Wright DW. Identification of ß-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity. Int J Parasitol Drugs Drug Resist. 2014 Dec; 4(3): 316-25. PMID: 25516843, PMCID: PMC4266794, PII: S2211-3207(14)00022-0, DOI: 10.1016/j.ijpddr.2014.08.002, ISSN: 2211-3207.

Davis KM, Gibson LE, Haselton FR, Wright DW. Simple sample processing enhances malaria rapid diagnostic test performance. Analyst [print-electronic]. 2014 Jun 6/21/2014; 139(12): 3026-31. PMID: 24787948, PMCID: PMC5098896, DOI: 10.1039/c4an00338a, ISSN: 1364-5528.

Gulka CP, Swartz JD, Trantum JR, Davis KM, Peak CM, Denton AJ, Haselton FR, Wright DW. Coffee rings as low-resource diagnostics: detection of the malaria biomarker Plasmodium falciparum histidine-rich protein-II using a surface-coupled ring of Ni(II)NTA gold-plated polystyrene particles. ACS Appl Mater Interfaces [print-electronic]. 2014 May 5/14/2014; 6(9): 6257-63. PMID: 24758478, DOI: 10.1021/am501452k, ISSN: 1944-8252.

Jackson SR, McBride JR, Rosenthal SJ, Wright DW. Where's the silver? Imaging trace silver coverage on the surface of gold nanorods. J. Am. Chem. Soc [print-electronic]. 2014 Apr 4/9/2014; 136(14): 5261-3. PMID: 24660654, DOI: 10.1021/ja501676y, ISSN: 1520-5126.

Adams NM, Wang KK, Caprioli AC, Thomas LC, Kankia B, Haselton FR, Wright DW. Quadruplex priming amplification for the detection of mRNA from surrogate patient samples. Analyst. 2014 Apr 4/7/2014; 139(7): 1644-52. PMID: 24503712, DOI: 10.1039/c3an02261g, ISSN: 1364-5528.

Davis KM, Bitting AL, Wright DW. On-particle detection of Plasmodium falciparum histidine-rich protein II by a "switch-on" iridium(III) probe. Anal. Biochem [print-electronic]. 2014 Jan 1/15/2014; 445: 60-6. PMID: 24129120, PII: S0003-2697(13)00485-5, DOI: 10.1016/j.ab.2013.10.007, ISSN: 1096-0309.

Stiebler R, Majerowicz D, Knudsen J, Gondim KC, Wright DW, Egan TJ, Oliveira MF. Unsaturated glycerophospholipids mediate heme crystallization: biological implications for hemozoin formation in the kissing bug Rhodnius prolixus. PLoS ONE. 2014; 9(2): e88976. PMID: 24586467, PMCID: PMC3935856, PII: PONE-D-13-36993, DOI: 10.1371/journal.pone.0088976, ISSN: 1932-6203.

Fong KY, Wright DW. Hemozoin and antimalarial drug discovery. Future Med Chem. 2013 Aug; 5(12): 1437-50. PMID: 23919553, PMCID: PMC4928194, DOI: 10.4155/fmc.13.113, ISSN: 1756-8927.

Stone JW, Thornburg NJ, Blum DL, Kuhn SJ, Wright DW, Crowe JE. Gold nanorod vaccine for respiratory syncytial virus. Nanotechnology [print-electronic]. 2013 Jul 7/26/2013; 24(29): 295102. PMID: 23799651, PMCID: PMC3754908, DOI: 10.1088/0957-4484/24/29/295102, ISSN: 1361-6528.

Adams NM, Olmsted IR, Haselton FR, Bornhop DJ, Wright DW. The effect of hybridization-induced secondary structure alterations on RNA detection using backscattering interferometry. Nucleic Acids Res [print-electronic]. 2013 May; 41(9): e103. PMID: 23519610, PMCID: PMC3643578, PII: gkt165, DOI: 10.1093/nar/gkt165, ISSN: 1362-4962.

Warnick KH, Wang B, Cliffel DE, Wright DW, Haglund RF, Pantelides ST. Room-temperature reactions for self-cleaning molecular nanosensors. Nano Lett [print-electronic]. 2013 Feb 2/13/2013; 13(2): 798-802. PMID: 23320817, DOI: 10.1021/nl304598p, ISSN: 1530-6992.

Adams NM, Creecy AE, Majors CE, Wariso BA, Short PA, Wright DW, Haselton FR. Design criteria for developing low-resource magnetic bead assays using surface tension valves. Biomicrofluidics. 2013; 7(1): 14104. PMID: 24403996, PMCID: PMC3562276, PII: 008301BMF, DOI: 10.1063/1.4788922, ISSN: 1932-1058.

Bordelon H, Russ PK, Wright DW, Haselton FR. A magnetic bead-based method for concentrating DNA from human urine for downstream detection. PLoS ONE [electronic-print]. 2013; 8(7): e68369. PMID: 23861895, PMCID: PMC3704639, PII: PONE-D-13-05340, DOI: 10.1371/journal.pone.0068369, ISSN: 1932-6203.

Stone JW, Harry R, Hendley O, Wright DW. Gold nanoparticle-oligonucleotide conjugates for the profiling of malignant melanoma phenotypes. Methods Mol. Biol. 2013; 1026: 111-9. PMID: 23749573, DOI: 10.1007/978-1-62703-468-5_9, ISSN: 1940-6029.

Perez JW, Adams NM, Zimmerman GR, Haselton FR, Wright DW. Detecting respiratory syncytial virus using nanoparticle-amplified immuno-PCR. Methods Mol. Biol. 2013; 1026: 93-110. PMID: 23749572, DOI: 10.1007/978-1-62703-468-5_8, ISSN: 1940-6029.

Harry RS, Hiatt LA, Kimmel DW, Carney CK, Halfpenny KC, Cliffel DE, Wright DW. Metabolic impact of 4-hydroxynonenal on macrophage-like RAW 264.7 function and activation. Chem. Res. Toxicol [print-electronic]. 2012 Aug 8/20/2012; 25(8): 1643-51. PMID: 22799741, PMCID: PMC3444243, DOI: 10.1021/tx3001048, ISSN: 1520-5010.

Davis KM, Swartz JD, Haselton FR, Wright DW. Low-resource method for extracting the malarial biomarker histidine-rich protein II to enhance diagnostic test performance. Anal. Chem [print-electronic]. 2012 Jul 7/17/2012; 84(14): 6136-42. PMID: 22734432, DOI: 10.1021/ac301030m, ISSN: 1520-6882.

Hiatt LA, McKenzie JR, Deravi LF, Harry RS, Wright DW, Cliffel DE. A printed superoxide dismutase coated electrode for the study of macrophage oxidative burst. Biosens Bioelectron [print-electronic]. 2012 Mar 3/15/2012; 33(1): 128-33. PMID: 22257735, PMCID: PMC3291099, PII: S0956-5663(11)00860-8, DOI: 10.1016/j.bios.2011.12.038, ISSN: 1873-4235.

Trantum JR, Wright DW, Haselton FR. Biomarker-mediated disruption of coffee-ring formation as a low resource diagnostic indicator. Langmuir [print-electronic]. 2012 Jan 1/31/2012; 28(4): 2187-93. PMID: 22148855, DOI: 10.1021/la203903a, ISSN: 1520-5827.

Adams NM, Jackson SR, Haselton FR, Wright DW. Design, synthesis, and characterization of nucleic-acid-functionalized gold surfaces for biomarker detection. Langmuir [print-electronic]. 2012 Jan 1/17/2012; 28(2): 1068-82. PMID: 21905721, PMCID: PMC4211628, DOI: 10.1021/la2028862, ISSN: 1520-5827.

Swartz JD, Gulka CP, Haselton FR, Wright DW. Development of a histidine-targeted spectrophotometric sensor using Ni(II)NTA-functionalized Au and Ag nanoparticles. Langmuir [print-electronic]. 2011 Dec 12/20/2011; 27(24): 15330-9. PMID: 22026818, DOI: 10.1021/la202937j, ISSN: 1520-5827.

Rock MT, McKinney BA, Yoder SM, Prudom CE, Wright DW, Crowe JE. Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. J. Immunol. Methods [print-electronic]. 2011 Nov 11/30/2011; 374(1-2): 13-7. PMID: 21854782, PMCID: PMC3220792, PII: S0022-1759(11)00209-2, DOI: 10.1016/j.jim.2011.08.004, ISSN: 1872-7905.

Sandlin RD, Carter MD, Lee PJ, Auschwitz JM, Leed SE, Johnson JD, Wright DW. Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization. Antimicrob. Agents Chemother [print-electronic]. 2011 Jul; 55(7): 3363-9. PMID: 21518844, PMCID: PMC3122397, PII: AAC.00121-11, DOI: 10.1128/AAC.00121-11, ISSN: 1098-6596.

Bordelon H, Adams NM, Klemm AS, Russ PK, Williams JV, Talbot HK, Wright DW, Haselton FR. Development of a low-resource RNA extraction cassette based on surface tension valves. ACS Appl Mater Interfaces [print-electronic]. 2011 Jun; 3(6): 2161-8. PMID: 21604768, PMCID: PMC3129697, DOI: 10.1021/am2004009, ISSN: 1944-8252.

Perez JW, Vargis EA, Russ PK, Haselton FR, Wright DW. Detection of respiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction. Anal. Biochem [print-electronic]. 2011 Mar 3/1/2011; 410(1): 141-8. PMID: 21111702, PMCID: PMC4208676, PII: S0003-2697(10)00746-3, DOI: 10.1016/j.ab.2010.11.033, ISSN: 1096-0309.

Miller SA, Hiatt LA, Keil RG, Wright DW, Cliffel DE. Multifunctional nanoparticles as simulants for a gravimetric immunoassay. Anal Bioanal Chem [print-electronic]. 2011 Jan; 399(3): 1021-9. PMID: 21110011, PMCID: PMC3031959, DOI: 10.1007/s00216-010-4419-8, ISSN: 1618-2650.

Hoang AN, Sandlin RD, Omar A, Egan TJ, Wright DW. The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates ß-hematin formation with an unusually low activation energy. Biochemistry [print-electronic]. 2010 Nov 11/30/2010; 49(47): 10107-16. PMID: 20979358, PMCID: PMC2996888, DOI: 10.1021/bi101397u, ISSN: 1520-4995.

Harry SR, Hicks DJ, Amiri KI, Wright DW. Hairpin DNA coated gold nanoparticles as intracellular mRNA probes for the detection of tyrosinase gene expression in melanoma cells. Chem. Commun. (Camb.) [print-electronic]. 2010 Aug 8/14/2010; 46(30): 5557-9. PMID: 20526488, DOI: 10.1039/c001969k, ISSN: 1364-548X.

Jayagopal A, Halfpenny KC, Perez JW, Wright DW. Hairpin DNA-functionalized gold colloids for the imaging of mRNA in live cells. J. Am. Chem. Soc. 2010 Jul 7/21/2010; 132(28): 9789-96. PMID: 20586450, PMCID: PMC2927968, DOI: 10.1021/ja102585v, ISSN: 1520-5126.

Halfpenny KC, Wright DW. Nanoparticle detection of respiratory infection. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 May; 2(3): 277-90. PMID: 20201109, DOI: 10.1002/wnan.83, ISSN: 1939-0041.

Carter MD, Phelan VV, Sandlin RD, Bachmann BO, Wright DW. Lipophilic mediated assays for beta-hematin inhibitors. Comb. Chem. High Throughput Screen. 2010 Mar; 13(3): 285-92. PMID: 20230372, PMCID: PMC2901836, ISSN: 1875-5402.

Reniere ML, Ukpabi GN, Harry SR, Stec DF, Krull R, Wright DW, Bachmann BO, Murphy ME, Skaar EP. The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Mol. Microbiol [print-electronic]. 2010 Mar; 75(6): 1529-38. PMID: 20180905, PMCID: PMC3800195, PII: MMI7076, DOI: 10.1111/j.1365-2958.2010.07076.x, ISSN: 1365-2958.

Boutaud O, Moore KP, Reeder BJ, Harry D, Howie AJ, Wang S, Carney CK, Masterson TS, Amin T, Wright DW, Wilson MT, Oates JA, Roberts LJ. Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2010 Feb 2/9/2010; 107(6): 2699-704. PMID: 20133658, PMCID: PMC2823910, PII: 0910174107, DOI: 10.1073/pnas.0910174107, ISSN: 1091-6490.

Hoang AN, Ncokazi KK, de Villiers KA, Wright DW, Egan TJ. Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles. Dalton Trans [print-electronic]. 2010 Feb 2/7/2010; 39(5): 1235-44. PMID: 20104349, PMCID: PMC2889375, DOI: 10.1039/b914359a, ISSN: 1477-9234.

Schrimpe AC, Wright DW. Differential gene expression mediated by 15-hydroxyeicosatetraenoic acid in LPS-stimulated RAW 264.7 cells. Malar. J. 2009 Aug 8/11/2009; 8: 195. PMID: 19671186, PMCID: PMC2743705, PII: 1475-2875-8-195, DOI: 10.1186/1475-2875-8-195, ISSN: 1475-2875.

Perez JW, Haselton FR, Wright DW. Viral detection using DNA functionalized gold filaments. Analyst [print-electronic]. 2009 Aug; 134(8): 1548-53. PMID: 20448919, PMCID: PMC2867084, DOI: 10.1039/b904191e, ISSN: 1364-5528.

Schrimpe AC, Wright DW. Comparative analysis of gene expression changes mediated by individual constituents of hemozoin. Chem. Res. Toxicol. 2009 Mar 3/16/2009; 22(3): 433-45. PMID: 19191707, PMCID: PMC4208677, PII: 10.1021/tx8002752, DOI: 10.1021/tx8002752, ISSN: 1520-5010.

Cseke G, Maginnis MS, Cox RG, Tollefson SJ, Podsiad AB, Wright DW, Dermody TS, Williams JV. Integrin alphavbeta1 promotes infection by human metapneumovirus. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2009 Feb 2/3/2009; 106(5): 1566-71. PMID: 19164533, PMCID: PMC2629439, PII: 0801433106, DOI: 10.1073/pnas.0801433106, ISSN: 1091-6490.

Eklund SE, Thompson RG, Snider RM, Carney CK, Wright DW, Wikswo J, Cliffel DE. Metabolic discrimination of select list agents by monitoring cellular responses in a multianalyte microphysiometer. Sensors (Basel) [print-electronic]. 2009; 9(3): 2117-33. PMID: 22574003, PMCID: PMC3345856, PII: s90302117, DOI: 10.3390/s90302117, ISSN: 1424-8220.

Deravi LF, Sumerel JL, Sewell SL, Wright DW. Piezoelectric inkjet printing of biomimetic inks for reactive surfaces. Small. 2008 Dec; 4(12): 2127-30. PMID: 18985670, DOI: 10.1002/smll.200800536, ISSN: 1613-6829.

Mok H, Lee S, Wright DW, Crowe JE. Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope. Vaccine [print-electronic]. 2008 Sep 9/2/2008; 26(37): 4775-82. PMID: 18662734, PMCID: PMC2561208, PII: S0264-410X(08)00934-1, DOI: 10.1016/j.vaccine.2008.07.012, ISSN: 0264-410X.

Sewell SL, Rutledge RD, Wright DW. Versatile biomimetic dendrimer templates used in the formation of TiO2 and GeO2. Dalton Trans [print-electronic]. 2008 Aug 8/7/2008; (29): 3857-65. PMID: 18629408, DOI: 10.1039/b802842g, ISSN: 1477-9226.

Rutledge RD, Huffman BJ, Cliffel DE, Wright DW. Design and synthesis of an antigenic mimic of the Ebola glycoprotein. J Mater Res. 2008; 23(12): 3161-8. PMID: 19609372, PMCID: PMC2711029, DOI: 10.1557/JMR.2008.0384, ISSN: 0884-2914.

Carter MD, Reese Harry S, Wright DW. Identification of hydroxyeicosatetraenoic acid components of schistosomal hemozoin. Biochem. Biophys. Res. Commun [print-electronic]. 2007 Nov 11/23/2007; 363(3): 867-72. PMID: 17904531, PMCID: PMC2705926, PII: S0006-291X(07)02039-6, DOI: 10.1016/j.bbrc.2007.09.051, ISSN: 0006-291X.

Williams JV, Chen Z, Cseke G, Wright DW, Keefer CJ, Tollefson SJ, Hessell A, Podsiad A, Shepherd BE, Sanna PP, Burton DR, Crowe JE, Williamson RA. A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J. Virol [print-electronic]. 2007 Aug; 81(15): 8315-24. PMID: 17522220, PMCID: PMC1951312, PII: JVI.00106-07, DOI: 10.1128/JVI.00106-07, ISSN: 0022-538X.

Lee S, Miller SA, Wright DW, Rock MT, Crowe JE. Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. J. Virol [print-electronic]. 2007 Mar; 81(5): 2349-58. PMID: 17182672, PMCID: PMC1865932, PII: JVI.01910-06, DOI: 10.1128/JVI.01910-06, ISSN: 0022-538X.

Cseke G, Wright DW, Tollefson SJ, Johnson JE, Crowe JE, Williams JV. Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J. Virol [print-electronic]. 2007 Jan; 81(2): 698-707. PMID: 17050599, PMCID: PMC1797435, PII: JVI.00844-06, DOI: 10.1128/JVI.00844-06, ISSN: 0022-538X.

Miller SA, Tollefson S, Crowe JE, Williams JV, Wright DW. Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region. J. Virol [print-electronic]. 2007 Jan; 81(1): 141-9. PMID: 17035305, PMCID: PMC1797239, PII: JVI.01243-06, DOI: 10.1128/JVI.01243-06, ISSN: 0022-538X.

Carney CK, Schrimpe AC, Halfpenny K, Harry RS, Miller CM, Broncel M, Sewell SL, Schaff JE, Deol R, Carter MD, Wright DW. The basis of the immunomodulatory activity of malaria pigment (hemozoin). J. Biol. Inorg. Chem [print-electronic]. 2006 Oct; 11(7): 917-29. PMID: 16868743, DOI: 10.1007/s00775-006-0147-0, ISSN: 0949-8257.

Wilburn JP, Wright DW, Cliffel DE. Imaging of voltage-gated alamethicin pores in a reconstituted bilayer lipid membrane via scanning electrochemical microscopy. Analyst [print-electronic]. 2006 Feb; 131(2): 311-6. PMID: 16440098, DOI: 10.1039/b510649d, ISSN: 0003-2654.

Gerdon AE, Wright DW, Cliffel DE. Epitope mapping of the protective antigen of B. anthracis by using nanoclusters presenting conformational peptide epitopes. Angew. Chem. Int. Ed. Engl. 2006 Jan 1/16/2006; 45(4): 594-8. PMID: 16355420, DOI: 10.1002/anie.200503328, ISSN: 1433-7851.

Gerdon AE, Wright DW, Cliffel DE. Hemagglutinin linear epitope presentation on monolayer-protected clusters elicits strong antibody binding. Biomacromolecules. 2005 Nov; 6(6): 3419-24. PMID: 16283774, DOI: 10.1021/bm050475o, ISSN: 1525-7797.

Miller CM, Carney CK, Schrimpe AC, Wright DW. Beta-Hematin (hemozoin) mediated decompostion of polyunsaturated fatty acids to 4-hydroxy-2-nonenal. Inorg Chem. 2005 Apr 4/4/2005; 44(7): 2134-6. PMID: 15792445, DOI: 10.1021/ic048821i, ISSN: 0020-1669.

Bentzen EL, House F, Utley TJ, Crowe JE, Wright DW. Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes. Nano Lett. 2005 Apr; 5(4): 591-5. PMID: 15826092, DOI: 10.1021/nl048073u, ISSN: 1530-6984.

Knecht MR, Sewell SL, Wright DW. Size control of dendrimer-templated silica. Langmuir. 2005 Mar 3/1/2005; 21(5): 2058-61. PMID: 15723511, DOI: 10.1021/la047800y, ISSN: 0743-7463.

Slocik JM, Wright DW. Screening of combinatorial Peptide libraries for nanocluster synthesis. Methods Mol. Biol. 2005; 303: 133-42. PMID: 15923681, PII: 1-59259-901-X:133, DOI: 10.1385/1-59259-901-X:133, ISSN: 1064-3745.

Edl J, Mernaugh R, Wright DW. Assays for selection of single-chain fragment variable recombinant antibodies to metal nanoclusters. Methods Mol. Biol. 2005; 303: 113-20. PMID: 15923679, PII: 1-59259-901-X:113, DOI: 10.1385/1-59259-901-X:113, ISSN: 1064-3745.

Gerdon AE, Wright DW, Cliffel DE. Quartz crystal microbalance detection of glutathione-protected nanoclusters using antibody recognition. Anal. Chem. 2005 Jan 1/1/2005; 77(1): 304-10. PMID: 15623309, DOI: 10.1021/ac048953t, ISSN: 0003-2700.

Knecht MR, Wright DW. Amine-terminated dendrimers as biomimetic templates for silica nanosphere formation. Langmuir. 2004 May 5/25/2004; 20(11): 4728-32. PMID: 15969189, ISSN: 0743-7463.

Knecht MR, Wright DW. Functional analysis of the biomimetic silica precipitating activity of the R5 peptide from Cylindrotheca fusiformis. Chem. Commun. (Camb.). 2003 Dec 12/21/2003; (24): 3038-9. PMID: 14703846, ISSN: 1359-7345.

Ziegler J, Pasierb L, Cole KA, Wright DW. Metalloporphyrin probes for antimalarial drug action. J. Inorg. Biochem. 2003 Sep 9/1/2003; 96(4): 478-86. PMID: 13678814, PII: S0162013403002538, ISSN: 0162-0134.

Slocik JM, Wright DW. Biomimetic mineralization of noble metal nanoclusters. Biomacromolecules. 2003 Sep; 4(5): 1135-41. PMID: 12959576, DOI: 10.1021/bm034003q, ISSN: 1525-7797.

Joseph M. Slocik, Joshua T. Moore and David W. Wright. Monoclonal Antibody Recognition of a Histidine-Rich Peptide Encapsulated Nanocluster. NanoLetters. 2002; ((2)): 169-73.

Joseph M. Slocik, Joshua T. Moore and David W. Wright. Immunoreactivity and Characterization of Histidine-Rich Peptide Encapsulated Nanoclusters. In Advanced Biomaterials-Characterization, Tissue. 2001; vol 711((MRS: Warrendale, PA)): 339-43.

Rachel Linck, James Ziegler, and David W. Wright. Heme Aggregation Inhibitors: Antimalarial Drugs Targeting an Essential Biomineralization Process. Current Medicinal Chemistry. 2001; 8: 171-89.

Jacqueline M. Whitling, Glen Spreitzer and David W. Wright. A Combinatorial and Informatics Approach to CdS Nanoclusters. Adv. Mat. 2000; 12: 1377-80.

James Ziegler, Theresa Schuerle, Crystal Kelly, Ashraf Elamin, Lisa Pasierb, Kelly A. Cole and David W. Wright. The Propionate of Heme Binds N4O2 Schiff Base Antimalarial Drug Complexes. Inorg. Chem. 2000; 39: 3731-3.

Christopher E. Dubé, David W. Wright, William H. Armstrong. Evidence for Cooperativity in the Disproportionation of H2O2 Efficiently Catalyzed by a Tetranuclear Manganese Complex. Angew. Chem. Int. Ed. 2000; 39: 2169-72.

Glen Spreitzer, Jacqueline M. Whitling, Jeffry D. Madura and David W. Wright. Peptide-Encapsulated CdS Nanoclusters from a Combinatorial Ligand Library. J. Roy. Soc., Chem. Commun. 2000; 209-10.

Kelly A. Cole, James Ziegler, Cathy A. Evans, and David W. Wright. Metalloporphyrins inhibit -Hematin (Hemozoin) Formation. J. Inorg. Biochem. 2000; 78: 109-15.

Jim Ziegler, Richard T. Chang, and David W. Wright. Multiple-Antigenic Peptides (MAP¿s) of Histidine-Rich Protein II of Plasmodium falciparum: Dendrimeric Biomineralization Templates. J. Am. Chem. Soc. 1999; 121: 2395-400.