Tracy E. Hunley, M.D.

Associate Professor

tray.hunley@vanderbilt.edu
Faculty Appointments
Associate Professor of Pediatrics
Education
M.D., University of Tennessee Center for Health Science, Memphis, TennesseeB.A., Molecular Biology , Vanderbilt University, Nashville, Tennessee
Office Address
Division of Pediatric Nephrology
2200 Children's Way
11133 Doctor's Office Tower
Nashville, TN 37232-9560
Publications
Bradshaw MJ, Vu N, Hunley TE, Chitnis T. Child Neurology: Neuromyelitis optica spectrum disorders. Neurology. 2017 Jan 1/10/2017; 88(2): e10-e13. PMID: 28069981, PII: WNL.0000000000003495, DOI: 10.1212/WNL.0000000000003495, ISSN: 1526-632X.

Taussig MD, Powell KP, Cole HA, Nwosu SK, Hunley T, Romine SE, Iwinski H, Talwalkar V, Warhoover T, Lovejoy SA, Mencio GA, Martus JE, Walker J, Milbrandt T, Schoenecker JG. Prevalence of Hypertension in Pediatric Tibia Vara and Slipped Capital Femoral Epiphysis. J Pediatr Orthop. 2016 Dec; 36(8): 877-83. PMID: 26090984, DOI: 10.1097/BPO.0000000000000569, ISSN: 1539-2570.

Sanyal M, Morimoto M, Baradaran-Heravi A, Choi K, Kambham N, Jensen K, Dutt S, Dionis-Petersen KY, Liu LX, Felix K, Mayfield C, Dekel B, Bokenkamp A, Fryssira H, Guillen-Navarro E, Lama G, Brugnara M, Lücke T, Olney AH, Hunley TE, Polat AI, Yis U, Bogdanovic R, Mitrovic K, Berry S, Najera L, Najafian B, Gentile M, Nur Semerci C, Tsimaratos M, Lewis DB, Boerkoel CF. Lack of IL7Ra expression in T cells is a hallmark of T-cell immunodeficiency in Schimke immuno-osseous dysplasia (SIOD). Clin. Immunol [print-electronic]. 2015 Dec; 161(2): 355-65. PMID: 26499378, PII: S1521-6616(15)30053-X, DOI: 10.1016/j.clim.2015.10.005, ISSN: 1521-7035.

Carroll C, Hunley TE, Guo Y, Cortez D. A novel splice site mutation in SMARCAL1 results in aberrant exon definition in a child with Schimke immunoosseous dysplasia. Am. J. Med. Genet. A [print-electronic]. 2015 Oct; 167A(10): 2260-4. PMID: 25943327, PMCID: PMC4743909, DOI: 10.1002/ajmg.a.37146, ISSN: 1552-4833.

Gbadegesin RA, Adeyemo A, Webb NJ, Greenbaum LA, Abeyagunawardena A, Thalgahagoda S, Kale A, Gipson D, Srivastava T, Lin JJ, Chand D, Hunley TE, Brophy PD, Bagga A, Sinha A, Rheault MN, Ghali J, Nicholls K, Abraham E, Janjua HS, Omoloja A, Barletta GM, Cai Y, Milford DD, O'Brien C, Awan A, Belostotsky V, Smoyer WE, Homstad A, Hall G, Wu G, Nagaraj S, Wigfall D, Foreman J, Winn MP, . HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. J. Am. Soc. Nephrol [print-electronic]. 2015 Jul; 26(7): 1701-10. PMID: 25349203, PMCID: PMC4483579, PII: ASN.2014030247, DOI: 10.1681/ASN.2014030247, ISSN: 1533-3450.

Kaseda R, Jabs K, Hunley TE, Jones D, Bian A, Allen RM, Vickers KC, Yancey PG, Linton MF, Fazio S, Kon V. Dysfunctional high-density lipoproteins in children with chronic kidney disease. Metab. Clin. Exp [print-electronic]. 2015 Feb; 64(2): 263-73. PMID: 25467845, PMCID: PMC4277938, PII: S0026-0495(14)00329-1, DOI: 10.1016/j.metabol.2014.10.020, ISSN: 1532-8600.

Carroll C, Badu-Nkansah A, Hunley T, Baradaran-Heravi A, Cortez D, Frangoul H. Schimke Immunoosseous Dysplasia associated with undifferentiated carcinoma and a novel SMARCAL1 mutation in a child. Pediatr Blood Cancer [print-electronic]. 2013 Sep; 60(9): E88-90. PMID: 23630135, PMCID: PMC3713188, DOI: 10.1002/pbc.24542, ISSN: 1545-5017.

Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Välimäki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW, Rasoulpour M, Thameem F, Al-Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature. 2012 Jan 1/22/2012; 482(7383): 98-102. PMID: 22266938, PMCID: PMC3278668, PII: nature10814, DOI: 10.1038/nature10814, ISSN: 1476-4687.

Dykes DM, Moore SR, Polk DB, Rosen MJ, Wills ML, Morris B, Maclin JS, Nogueira J, Katz A, Hunley TE, Pugh J, Saeed S. Mycophenolate mofetil-related enterocolitis and weight loss: a pediatric case series. Case Rep Pediatr [print-electronic]. 2012; 2012: 624168. PMID: 23133776, PMCID: PMC3485763, DOI: 10.1155/2012/624168, ISSN: 2090-6811.

Yamamoto S, Zuo Y, Ma J, Yancey PG, Hunley TE, Motojima M, Fogo AB, Linton MF, Fazio S, Ichikawa I, Kon V. Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice. Nephrol. Dial. Transplant [print-electronic]. 2011 Aug; 26(8): 2491-7. PMID: 21245127, PMCID: PMC3203394, PII: gfq759, DOI: 10.1093/ndt/gfq759, ISSN: 1460-2385.

Herzenberg AM, Fogo AB, Reich HN, Troyanov S, Bavbek N, Massat AE, Hunley TE, Hladunewich MA, Julian BA, Fervenza FC, Cattran DC. Validation of the Oxford classification of IgA nephropathy. Kidney Int [print-electronic]. 2011 Aug; 80(3): 310-7. PMID: 21544062, PII: S0085-2538(15)55026-6, DOI: 10.1038/ki.2011.126, ISSN: 1523-1755.

Ma LJ, Corsa BA, Zhou J, Yang H, Li H, Tang YW, Babaev VR, Major AS, Linton MF, Fazio S, Hunley TE, Kon V, Fogo AB. Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity. Am. J. Physiol. Renal Physiol [print-electronic]. 2011 May; 300(5): F1203-13. PMID: 21367915, PMCID: PMC3094053, PII: ajprenal.00468.2010, DOI: 10.1152/ajprenal.00468.2010, ISSN: 1522-1466.

Hunley TE, Ma LJ, Kon V. Scope and mechanisms of obesity-related renal disease. Curr. Opin. Nephrol. Hypertens. 2010 May; 19(3): 227-34. PMID: 20134323, PMCID: PMC2897176, DOI: 10.1097/MNH.0b013e3283374c09, ISSN: 1473-6543.

Hunley TE, Kon V. Glomerular filtration: still sympathetic to endothelin's influence? [editorial]. J. Am. Soc. Nephrol [print-electronic]. 2009 Jul; 20(7): 1427-9. PMID: 19520752, PII: ASN.2009050503, DOI: 10.1681/ASN.2009050503, ISSN: 1533-3450.

Fowler SM, Kon V, Ma L, Richards WO, Fogo AB, Hunley TE. Obesity-related focal and segmental glomerulosclerosis: normalization of proteinuria in an adolescent after bariatric surgery. Pediatr. Nephrol [print-electronic]. 2009 Apr; 24(4): 851-5. PMID: 18941798, DOI: 10.1007/s00467-008-1024-6, ISSN: 0931-041X.

Hunley TE, Spring MD, Peters TR, Weikert DR, Jabs K. Clostridium septicum myonecrosis complicating diarrhea-associated hemolytic uremic syndrome. Pediatr. Nephrol [print-electronic]. 2008 Jul; 23(7): 1171-5. PMID: 18301926, DOI: 10.1007/s00467-008-0774-5, ISSN: 0931-041X.

Hunley TE, Kon V, Jabs K. Myocardial infarction in chronic kidney disease. Pediatrics. 2008 Jul; 122(1): 223-4; author reply 224. PMID: 18596019, PII: 122/1/223, DOI: 10.1542/peds.2008-0943, ISSN: 1098-4275.

Agarwal HS, Taylor MB, Grzeszczak MJ, Lovvorn HN, Hunley TE, Jabs K, Shankar V. Extra corporeal membrane oxygenation and plasmapheresis for pulmonary hemorrhage in microscopic polyangiitis. Pediatr. Nephrol [print-electronic]. 2005 Apr; 20(4): 526-8. PMID: 15714314, DOI: 10.1007/s00467-004-1724-5, ISSN: 0931-041X.

Hunley TE, Corzo D, Dudek M, Kishnani P, Amalfitano A, Chen YT, Richards SM, Phillips JA, Fogo AB, Tiller GE. Nephrotic syndrome complicating alpha-glucosidase replacement therapy for Pompe disease. Pediatrics. 2004 Oct; 114(4): e532-5. PMID: 15466083, PII: 114/4/e532, DOI: 10.1542/peds.2003-0988-L, ISSN: 1098-4275.

Hunley TE, Kon V. Update on endothelins - biology and clinical implications. Pediatr. Nephrol. 2001 Sep; 16(9): 752-62. PMID: 11511995, DOI: 10.1007/s0046710160752, ISSN: 0931-041X.

Hunley TE, Tamura M, Stoneking BJ, Nishimura H, Ichiki T, Inagami T, Kon V. The angiotensin type II receptor tonically inhibits angiotensin- converting enzyme in AT2 null mutant mice. Kidney Int. 2000 Feb; 57(2): 570-7. PMID: 10652034, PII: kid877, DOI: 10.1046/j.1523-1755.2000.00877.x, ISSN: 0085-2538.

Hohenfellner K, Hunley TE, Brezinska R, Brodhag P, Shyr Y, Brenner W, Habermehl P, Kon V. ACE I/D gene polymorphism predicts renal damage in congenital uropathies. Pediatr. Nephrol. 1999 Aug; 13(6): 514-8. PMID: 10452281, DOI: 10.1007/s004670050649, ISSN: 0931-041X.

Tsuchida S, Miyazaki Y, Matsusaka T, Hunley TE, Inagami T, Fogo A, Ichikawa I. Potent antihypertrophic effect of the bradykinin B2 receptor system on the renal vasculature. Kidney Int. 1999 Aug; 56(2): 509-16. PMID: 10432390, PII: kid574, DOI: 10.1046/j.1523-1755.1999.00574.x, ISSN: 0085-2538.

Hohenfellner K, Hunley TE, Schloemer C, Brenner W, Yerkes E, Zepp F, Brock JW, Kon V. Angiotensin type 2 receptor is important in the normal development of the ureter. Pediatr. Nephrol. 1999 Apr; 13(3): 187-91. PMID: 10353402, ISSN: 0931-041X.

Hunley TE, Kon V. IgA nephropathy. Curr. Opin. Pediatr. 1999 Apr; 11(2): 152-7. PMID: 10202625, ISSN: 1040-8703.

Hohenfellner K, Hunley TE, Yerkes E, Habermehl P, Hohenfellner R, Kon V. Angiotensin II, type 2 receptor in the development of vesico-ureteric reflux. BJU Int. 1999 Feb; 83(3): 318-22. PMID: 10233502, ISSN: 1464-4096.

Paueksakon P, Hunley TE, Lee SM, Fogo AB. A 12-year-old girl with pulmonary hemorrhage, skin lesions, and hematuria. Am. J. Kidney Dis. 1999 Feb; 33(2): 404-9. PMID: 10023658, PII: S0272-6386(99)70321-5, ISSN: 1523-6838.

Nishimura H, Yerkes E, Hohenfellner K, Miyazaki Y, Ma J, Hunley TE, Yoshida H, Ichiki T, Threadgill D, Phillips JA, Hogan BM, Fogo A, Brock JW, Inagami T, Ichikawa I. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. Mol. Cell. 1999 Jan; 3(1): 1-10. PMID: 10024874, PII: S1097-2765(00)80169-0, ISSN: 1097-2765.

Brock JW, Hunley TE, Adams MC, Kon V. Role of the renin-angiotensin system in disorders of the urinary tract. J. Urol. 1998 Nov; 160(5): 1812-9. PMID: 9783965, PII: S0022-5347(01)62423-6, ISSN: 0022-5347.

Stoneking BJ, Hunley TE, Nishimura H, Ma J, Fogo A, Inagami T, Tamura M, Adams MC, Brock JW, Kon V. Renal angiotensin converting enzyme promotes renal damage during ureteral obstruction. J. Urol. 1998 Sep; 160(3 Pt 2): 1070-4. PMID: 9719278, ISSN: 0022-5347.

Hunley TE, Yared A, Fogo A, MacDonell RC. Nephrotic syndrome in an adolescent: the cry of the wolf. Am. J. Kidney Dis. 1998 Jan; 31(1): 155-60. PMID: 9428468, PII: S0272638698000249, ISSN: 1523-6838.

Gainer JV, Hunley TE, Kon V, Nadeau JH, Muldowney JA, Brown NJ. Angiotensin II type I receptor polymorphism in African Americans lower frequency of the C1166 variant. Biochem. Mol. Biol. Int. 1997 Sep; 43(1): 227-31. PMID: 9315301, ISSN: 1039-9712.

Brock JW, Adams M, Hunley T, Wada A, Trusler L, Kon V. Potential risk factors associated with progressive renal damage in childhood urological diseases: the role of angiotensin-converting enzyme gene polymorphism. J. Urol. 1997 Sep; 158(3 Pt 2): 1308-11. PMID: 9258202, PII: S0022-5347(01)64463-X, ISSN: 0022-5347.

Hunley TE, Kon V. Endothelin in ischemic acute renal failure. Curr. Opin. Nephrol. Hypertens. 1997 Jul; 6(4): 394-400. PMID: 9263691, ISSN: 1062-4821.

Brock JW 3rd. Adams M. Hunley T. Wada A. Trusler L. Kon V. Potential risk factors associated with progressive renal damage in childhood urological diseases: the role of angiotensin-converting enzyme gene polymorphism. Journal of Urology. 1997; 158((3 Pt 2)): 1308-11.

Hunley TE, Julian BA, Phillips JA, Summar ML, Yoshida H, Horn RG, Brown NJ, Fogo A, Ichikawa I, Kon V. Angiotensin converting enzyme gene polymorphism: potential silencer motif and impact on progression in IgA nephropathy. Kidney Int. 1996 Feb; 49(2): 571-7. PMID: 8821846, ISSN: 0085-2538.

Kon V, Hunley TE, Fogo A. Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Studies in chronic cyclosporine nephrotoxicity in rats. Transplantation. 1995 Jul 7/15/1995; 60(1): 89-95. PMID: 7624949, ISSN: 0041-1337.

Hunley TE, Iwasaki S, Homma T, Kon V. Nitric oxide and endothelin in pathophysiological settings. Pediatr. Nephrol. 1995 Apr; 9(2): 235-44. PMID: 7794725, ISSN: 0931-041X.

Hunley TE, Fogo A, Iwasaki S, Kon V. Endothelin A receptor mediates functional but not structural damage in chronic cyclosporine nephrotoxicity. J. Am. Soc. Nephrol. 1995 Mar; 5(9): 1718-23. PMID: 7780063, ISSN: 1046-6673.