Tatsuki Koyama, Ph.D.



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Faculty Appointments
Professor of Biostatistics
Ph.D., Statistics, University of Pittsburgh, Pittsburgh, PennsylvaniaM.A., Statistics, University of Pittsburgh, Pittsburgh, PennsylvaniaB.A., Statistics, University of California, Berkeley, California
Office Address
571 Preston Research Building
Nashville, TN 37232-6848
Research Description
Research interests include: group sequential methods; two-stage adaptive procedures (phase II / phase III); noninferiority / superiority / equivalence trials; statistics in basic science; statistical graphics
Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Am J Gastroenterol. 2022 Feb 2/1/2022; 117(2): 272-9. PMID: 34932022, PMCID: PMC8858426, PII: 00000434-202202000-00018, DOI: 10.14309/ajg.0000000000001587, ISSN: 1572-0241.

Wallis CJD, Huang LC, Zhao Z, Penson DF, Koyama T, Conwill R, Tallman JE, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Barocas DA, Hoffman KE. Association between pelvic nodal radiotherapy and patient-reported functional outcomes through 5 years among men undergoing external-beam radiotherapy for prostate cancer: An assessment of the comparative effectiveness analysis of surgery and radiation (CEASAR) cohort. Urol Oncol [print-electronic]. 2022 Feb; 40(2): 56.e1-56.e8. PMID: 34154899, PII: S1078-1439(21)00191-5, DOI: 10.1016/j.urolonc.2021.04.035, ISSN: 1873-2496.

Luckenbaugh AN, Wallis CJD, Huang LC, Wittmann D, Klaassen Z, Zhao Z, Koyama T, Laviana AA, Conwill R, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Hoffman KE, Penson DF, Barocas DA. Association Between Treatment for Localized Prostate Cancer and Mental Health Outcomes. J Urol [print-electronic]. 2022 Jan 1/3/2022; 101097JU0000000000002370. PMID: 34978488, DOI: 10.1097/JU.0000000000002370, ISSN: 1527-3792.

Wallis CJD, Zhao Z, Huang LC, Penson DF, Koyama T, Kaplan SH, Greenfield S, Luckenbaugh AN, Klaassen Z, Conwill R, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Hoffman KE, Barocas DA. Association of Treatment Modality, Functional Outcomes, and Baseline Characteristics With Treatment-Related Regret Among Men With Localized Prostate Cancer. JAMA Oncol. 2022 Jan 1/1/2022; 8(1): 50-9. PMID: 34792527, PMCID: PMC8603232, PII: 2786406, DOI: 10.1001/jamaoncol.2021.5160, ISSN: 2374-2445.

Pal T, Hull PC, Koyama T, Lammers P, Martinez D, McArthy J, Schremp E, Tezak A, Washburn A, Whisenant JG, Friedman DL. Enhancing Cancer care of rural dwellers through telehealth and engagement (ENCORE): protocol to evaluate effectiveness of a multi-level telehealth-based intervention to improve rural cancer care delivery. BMC Cancer. 2021 Nov 11/23/2021; 21(1): 1262. PMID: 34814868, PMCID: PMC8609269, PII: 10.1186/s12885-021-08949-4, DOI: 10.1186/s12885-021-08949-4, ISSN: 1471-2407.

Cheng AC, Wen L, Li Y, Koyama T, Berry LD, Pal T, Friedman DL, Osterman TJ. Follow-up Interactive Long-Term Expert Ranking (FILTER): a crowdsourcing platform to adjudicate risk for survivorship care. JAMIA Open. 2021 Oct; 4(4): ooab090. PMID: 34755049, PMCID: PMC8571913, PII: ooab090, DOI: 10.1093/jamiaopen/ooab090, ISSN: 2574-2531.

Harvey ML, Lin AS, Sun L, Koyama T, Shuman JHB, Loh JT, Algood HMS, Scholz MB, McClain MS, Cover TL. Enhanced Fitness of a Helicobacter pylori babA Mutant in a Murine Model. Infect Immun [print-electronic]. 2021 Sep 9/16/2021; 89(10): e0072520. PMID: 34310886, PMCID: PMC8445181, DOI: 10.1128/IAI.00725-20, ISSN: 1098-5522.

Daniels AB, Froehler MT, Kaczmarek JV, Bogan CM, Santapuram PR, Pierce JM, Chen SC, Schremp EA, Boyd KL, Tao YK, Calcutt MW, Koyama T, Richmond A, Friedman DL. Efficacy, Toxicity, and Pharmacokinetics of Intra-Arterial Chemotherapy Versus Intravenous Chemotherapy for Retinoblastoma in Animal Models and Patients. Transl Vis Sci Technol. 2021 Sep 9/1/2021; 10(11): 10. PMID: 34495330, PMCID: PMC8431978, PII: 2777880, DOI: 10.1167/tvst.10.11.10, ISSN: 2164-2591.

Kerchberger VE, Brown RM, Semler MW, Zhao Z, Koyama T, Janz DR, Bastarache JA, Ware LB. Impact of Clinician Recognition of Acute Respiratory Distress Syndrome on Evidenced-Based Interventions in the Medical ICU. Crit Care Explor. 2021 Jul; 3(7): e0457. PMID: 34250497, PMCID: PMC8263322, DOI: 10.1097/CCE.0000000000000457, ISSN: 2639-8028.

Joyce DD, Wallis CJD, Luckenbaugh AN, Huelster HL, Zhao Z, Hoffman KE, Huang LC, Koyama T, Conwill R, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, Neil BBO, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Sexual function outcomes of radiation and androgen deprivation therapy for localized prostate cancer in men with good baseline function. Prostate Cancer Prostatic Dis [print-electronic]. 2021 Jun 6/9/2021; PMID: 34108648, PII: 10.1038/s41391-021-00405-5, DOI: 10.1038/s41391-021-00405-5, ISSN: 1476-5608.

Pasalic D, Barocas DA, Huang LC, Zhao Z, Koyama T, Tang C, Conwill R, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup AM, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Hoffman KE. Five-year outcomes from a prospective comparative effectiveness study evaluating external-beam radiotherapy with or without low-dose-rate brachytherapy boost for localized prostate cancer. Cancer [print-electronic]. 2021 Jun 6/1/2021; 127(11): 1912-25. PMID: 33595853, DOI: 10.1002/cncr.33388, ISSN: 1097-0142.

Daniels AB, Patel SN, Milam RW, Kohanim S, Friedman DL, Koyama T. Effect of Intravenous Chemotherapy Regimen on Globe Salvage Success Rates for Retinoblastoma Based on Disease Class-A Meta-Analysis. Cancers (Basel). 2021 May 5/6/2021; 13(9): PMID: 34066325, PMCID: PMC8125212, PII: cancers13092216, DOI: 10.3390/cancers13092216, ISSN: 2072-6694.

Stone BV, Laviana AA, Luckenbaugh AN, Huang LC, Zhao Z, Koyama T, Conwill R, Hoffman K, Joyce DD, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Patient-Reported Financial Toxicity Associated with Contemporary Treatment for Localized Prostate Cancer. J Urol [print-electronic]. 2021 Mar; 205(3): 761-8. PMID: 33252300, DOI: 10.1097/JU.0000000000001423, ISSN: 1527-3792.

Santapuram PR, Schremp EA, Friedman DL, Koyama T, Froehler MT, Daniels AB. Adverse Events, Treatment Burden, and Outcomes of Intravenous versus Intra-arterial Chemotherapy for Retinoblastoma. Ophthalmol Retina [print-electronic]. 2021 Mar; 5(3): 309-12. PMID: 32920208, PII: S2468-6530(20)30370-5, DOI: 10.1016/j.oret.2020.09.006, ISSN: 2468-6530.

Huelster HL, Laviana AA, Joyce DD, Huang LC, Zhao Z, Koyama T, Hoffman KE, Conwill R, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg M, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Radiotherapy after radical prostatectomy: Effect of timing of postprostatectomy radiation on functional outcomes. Urol Oncol [print-electronic]. 2020 Dec; 38(12): 930.e23-930.e32. PMID: 32736934, PMCID: PMC8095316, PII: S1078-1439(20)30290-8, DOI: 10.1016/j.urolonc.2020.06.022, ISSN: 1873-2496.

Reisz PA, Laviana AA, Zhao Z, Huang LC, Koyama T, Conwill R, Hoffman K, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Assessing the Quality of Surgical Care for Clinically Localized Prostate Cancer: Results from the CEASAR Study. J Urol [print-electronic]. 2020 Dec; 204(6): 1236-41. PMID: 32568605, DOI: 10.1097/JU.0000000000001198, ISSN: 1527-3792.

Coronado RA, Ehde DM, Pennings JS, Vanston SW, Koyama T, Phillips SE, Mathis SL, McGirt MJ, Spengler DM, Aaronson OS, Cheng JS, Devin CJ, Wegener ST, Archer KR. Psychosocial Mechanisms of Cognitive-Behavioral-Based Physical Therapy Outcomes After Spine Surgery: Preliminary Findings From Mediation Analyses. Phys Ther. 2020 Sep 9/28/2020; 100(10): 1793-804. PMID: 32556249, PMCID: PMC7530577, PII: 5859493, DOI: 10.1093/ptj/pzaa112, ISSN: 1538-6724.

Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Urology [print-electronic]. 2020 Aug; 142: 1-13. PMID: 32446805, PMCID: PMC7387170, PII: S0090-4295(20)30526-4, DOI: 10.1016/j.urology.2020.05.002, ISSN: 1527-9995.

Wang C, Wolters PJ, Calfee CS, Liu S, Balmes JR, Zhao Z, Koyama T, Ware LB. Long-term ozone exposure is positively associated with telomere length in critically ill patients. Environ Int [print-electronic]. 2020 Aug; 141: 105780. PMID: 32417614, PMCID: PMC7535086, PII: S0160-4120(19)34845-7, DOI: 10.1016/j.envint.2020.105780, ISSN: 1873-6750.

Laviana AA, Zhao Z, Huang LC, Koyama T, Conwill R, Hoffman K, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Development and Internal Validation of a Web-based Tool to Predict Sexual, Urinary, and Bowel Function Longitudinally After Radiation Therapy, Surgery, or Observation. Eur Urol [print-electronic]. 2020 Aug; 78(2): 248-55. PMID: 32098731, PMCID: PMC7384934, PII: S0302-2838(20)30104-4, DOI: 10.1016/j.eururo.2020.02.007, ISSN: 1873-7560.

Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology [letter]. BJU Int [print-electronic]. 2020 Jul; 126(1): 14-25. PMID: 32542947, DOI: 10.1111/bju.15102, ISSN: 1464-410X.

Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Eur Urol [print-electronic]. 2020 Jul; 78(1): 97-109. PMID: 32451178, PII: S0302-2838(20)30316-X, DOI: 10.1016/j.eururo.2020.04.048, ISSN: 1873-7560.

Vickers AJ, Assel MJ, Sjoberg DD, Qin R, Zhao Z, Koyama T, Botchway A, Wang X, Huo D, Kattan M, Zabor EC, Harrell F. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. J Urol [print-electronic]. 2020 Jul; 204(1): 121-33. PMID: 32441187, DOI: 10.1097/JU.0000000000001096, ISSN: 1527-3792.

Hoffman KE, Penson DF, Zhao Z, Huang LC, Conwill R, Laviana AA, Joyce DD, Luckenbaugh AN, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Koyama T, Barocas DA. Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer. JAMA. 2020 Jan 1/14/2020; 323(2): 149-63. PMID: 31935027, PMCID: PMC6990712, PII: 2758599, DOI: 10.1001/jama.2019.20675, ISSN: 1538-3598.

Kerchberger VE, Huang Y, Koyama T, Shoemaker MB, Darbar D, Bastarache JA, Ware LB, Shaver CM. Clinical and Genetic Contributors to New-Onset Atrial Fibrillation in Critically Ill Adults. Crit Care Med. 2020 Jan; 48(1): 22-30. PMID: 31599812, PMCID: PMC6910934, DOI: 10.1097/CCM.0000000000004034, ISSN: 1530-0293.

Laviana AA, Hernandez A, Huang LC, Zhao Z, Koyama T, Conwill R, Hoffman K, Feurer ID, Goodman M, Hamilton AS, Wu XC, Paddock LE, Stroup A, Cooperberg MR, Hashibe M, O'Neil BB, Kaplan SH, Greenfield S, Penson DF, Barocas DA. Interpretation of Domain Scores on the EPIC-How Does the Domain Score Translate into Functional Outcomes?. J Urol [print-electronic]. 2019 Dec; 202(6): 1150-8. PMID: 31216252, PMCID: PMC8627681, DOI: 10.1097/JU.0000000000000392, ISSN: 1527-3792.

Dallmer JR, Robles J, Wile GE, Koyama T, Barocas DA. The Harms of Hematuria Evaluation: Modeling the Risk-Benefit of Using Split Bolus Computerized Tomography Urography to Reduce Radiation Exposure in a Theoretical Cohort. J Urol [print-electronic]. 2019 Nov; 202(5): 899-904. PMID: 31188730, DOI: 10.1097/JU.0000000000000387, ISSN: 1527-3792.

Duffy C, Hall L, Godown J, Koyama T, Borinstein SC. Steroid-induced Bradycardia During Induction Chemotherapy in Children and Young Adults Diagnosed With Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma. J Pediatr Hematol Oncol. 2019 Oct; 41(7): 537-41. PMID: 30994505, DOI: 10.1097/MPH.0000000000001483, ISSN: 1536-3678.

Cunningham-Erves J, Koyama T, Huang Y, Jones J, Wilkins CH, Harnack L, McAfee C, Hull PC. Providers' Perceptions of Parental Human Papillomavirus Vaccine Hesitancy: Cross-Sectional Study. JMIR Cancer. 2019 Jul 7/2/2019; 5(2): e13832. PMID: 31267976, PMCID: PMC6632100, PII: v5i2e13832, DOI: 10.2196/13832, ISSN: 2369-1999.

de la Fuente J, Dhedin N, Koyama T, Bernaudin F, Kuentz M, Karnik L, Socié G, Culos KA, Brodsky RA, DeBaun MR, Kassim AA. Haploidentical Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide Plus Thiotepa Improves Donor Engraftment in Patients with Sickle Cell Anemia: Results of an International Learning Collaborative. Biol Blood Marrow Transplant [print-electronic]. 2019 Jun; 25(6): 1197-209. PMID: 30500440, PII: S1083-8791(18)30772-9, DOI: 10.1016/j.bbmt.2018.11.027, ISSN: 1523-6536.

Fowke JH, Koyama T, Dai Q, Zheng SL, Xu J, Howard LE, Freedland SJ. Blood and dietary magnesium levels are not linked with lower prostate cancer risk in black or white men. Cancer Lett [print-electronic]. 2019 May 5/1/2019; 449: 99-105. PMID: 30776477, PMCID: PMC6954048, PII: S0304-3835(19)30101-6, DOI: 10.1016/j.canlet.2019.02.023, ISSN: 1872-7980.

Goff LW, Azad NS, Stein S, Whisenant JG, Koyama T, Vaishampayan U, Hochster H, Connolly R, Weise A, LoRusso PM, Salaria SN, El-Rifai W, Berlin JD. Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer. Invest New Drugs [print-electronic]. 2019 Apr; 37(2): 315-22. PMID: 30191522, PMCID: PMC6401337, PII: 10.1007/s10637-018-0663-0, DOI: 10.1007/s10637-018-0663-0, ISSN: 1573-0646.

Assel M, Sjoberg D, Elders A, Wang X, Huo D, Botchway A, Delfino K, Fan Y, Zhao Z, Koyama T, Hollenbeck B, Qin R, Zahnd W, Zabor EC, Kattan MW, Vickers AJ. Guidelines for Reporting of Statistics for Clinical Research in Urology. J Urol. 2019 Mar; 201(3): 595-604. PMID: 30633111, PMCID: PMC6600813, DOI: 10.1097/JU.0000000000000001, ISSN: 1527-3792.

Assel M, Sjoberg D, Elders A, Wang X, Huo D, Botchway A, Delfino K, Fan Y, Zhao Z, Koyama T, Hollenbeck B, Qin R, Zahnd W, Zabor EC, Kattan MW, Vickers AJ. Guidelines for Reporting of Statistics for Clinical Research in Urology [editorial]. Eur Urol [print-electronic]. 2019 Mar; 75(3): 358-67. PMID: 30580902, PMCID: PMC6391870, PII: S0302-2838(18)31002-9, DOI: 10.1016/j.eururo.2018.12.014, ISSN: 1873-7560.

Assel M, Sjoberg D, Elders A, Wang X, Huo D, Botchway A, Delfino K, Fan Y, Zhao Z, Koyama T, Hollenbeck B, Qin R, Zahnd W, Zabor EC, Kattan MW, Vickers AJ. Guidelines for reporting of statistics for clinical research in urology. BJU Int [print-electronic]. 2019 Mar; 123(3): 401-10. PMID: 30537407, PMCID: PMC6397060, DOI: 10.1111/bju.14640.

Maseda D, Zackular JP, Trindade B, Kirk L, Roxas JL, Rogers LM, Washington MK, Du L, Koyama T, Viswanathan VK, Vedantam G, Schloss PD, Crofford LJ, Skaar EP, Aronoff DM. Nonsteroidal Anti-inflammatory Drugs Alter the Microbiota and Exacerbate Clostridium difficile Colitis while Dysregulating the Inflammatory Response. MBio. 2019 Jan 1/8/2019; 10(1): PMID: 30622186, PMCID: PMC6325247, PII: mBio.02282-18, DOI: 10.1128/mBio.02282-18, ISSN: 2150-7511.

Das S, Shi C, Koyama T, Huang Y, Gonzalez R, Idrees K, Bailey CE, Berlin J. Peritoneal Carcinomatosis in Well-Differentiated Small-Intestinal Neuroendocrine Tumors with Mesenteric Tumor Deposits. J Med Surg Pathol [print-electronic]. 2019; 4(1): 1-10. PMID: 32322781, PMCID: PMC7175957, ISSN: 2472-4971.

Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB. Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. Am J Respir Crit Care Med. 2019 Jan 1/1/2019; 199(1): 62-70. PMID: 30067389, PMCID: PMC6353017, DOI: 10.1164/rccm.201803-0435OC, ISSN: 1535-4970.

Goff LW, Azad NS, Stein S, Whisenant JG, Koyama T, Vaishampayan U, Hochster H, Connolly R, Weise A, LoRusso PM, Salaria SN, El-Rifai W, Berlin JD. Correction to: Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer. Invest New Drugs. 2018 Dec; 36(6): 1158. PMID: 30334109, PII: 10.1007/s10637-018-0679-5, DOI: 10.1007/s10637-018-0679-5, ISSN: 1573-0646.

Hull PC, Buchowski M, Canedo JR, Beech BM, Du L, Koyama T, Zoorob R. Childhood obesity prevention cluster randomized trial for Hispanic families: outcomes of the healthy families study. Pediatr Obes [print-electronic]. 2018 Nov; 13(11): 686-96. PMID: 27884047, PMCID: PMC5443700, DOI: 10.1111/ijpo.12197, ISSN: 2047-6310.

Lee DJ, Barocas DA, Zhao Z, Huang LC, Koyama T, Resnick MJ, Conwill R, McCollum D, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hashibe M, Kaplan SH, Paddock LE, Stroup AM, Wu XC, Penson DF, Hoffman KE. Contemporary prostate cancer radiation therapy in the United States: Patterns of care and compliance with quality measures. Pract Radiat Oncol. 2018 Sep; 8(5): 307-16. PMID: 30177030, PMCID: PMC7492101, PII: S1879-8500(18)30139-5, DOI: 10.1016/j.prro.2018.04.009, ISSN: 1879-8519.

Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. Thorax [print-electronic]. 2018 Sep; 73(9): 840-6. PMID: 29903755, PMCID: PMC6410734, PII: thoraxjnl-2017-211280, DOI: 10.1136/thoraxjnl-2017-211280, ISSN: 1468-3296.

Tyson MD, Koyama T, Lee D, Hoffman KE, Resnick MJ, Wu XC, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hashibe M, Paddock LE, Stroup A, Chen V, Conwill R, McCollum D, Penson DF, Barocas DA. Effect of Prostate Cancer Severity on Functional Outcomes After Localized Treatment: Comparative Effectiveness Analysis of Surgery and Radiation Study Results. Eur Urol [print-electronic]. 2018 Jul; 74(1): 26-33. PMID: 29501451, PMCID: PMC7643873, PII: S0302-2838(18)30119-2, DOI: 10.1016/j.eururo.2018.02.012, ISSN: 1873-7560.

McAlister RK, Aston J, Pollack M, Du L, Koyama T, Chism DD. Effect of Concomitant pH-Elevating Medications with Pazopanib on Progression-Free Survival and Overall Survival in Patients with Metastatic Renal Cell Carcinoma. Oncologist [print-electronic]. 2018 Jun; 23(6): 686-92. PMID: 29487220, PMCID: PMC6067930, PII: theoncologist.2017-0578, DOI: 10.1634/theoncologist.2017-0578, ISSN: 1549-490X.

Avulova S, Zhao Z, Lee D, Huang LC, Koyama T, Hoffman KE, Conwill RM, Wu XC, Chen V, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hashibe M, Paddock LE, Stroup A, Resnick MJ, Penson DF, Barocas DA. The Effect of Nerve Sparing Status on Sexual and Urinary Function: 3-Year Results from the CEASAR Study. J Urol [print-electronic]. 2018 May; 199(5): 1202-9. PMID: 29253578, PII: S0022-5347(17)78114-1, DOI: 10.1016/j.juro.2017.12.037, ISSN: 1527-3792.

Scoville EA, Allaman MM, Brown CT, Motley AK, Horst SN, Williams CS, Koyama T, Zhao Z, Adams DW, Beaulieu DB, Schwartz DA, Wilson KT, Coburn LA. Alterations in Lipid, Amino Acid, and Energy Metabolism Distinguish Crohn's Disease from Ulcerative Colitis and Control Subjects by Serum Metabolomic Profiling. Metabolomics [print-electronic]. 2018 Jan; 14(1): 17. PMID: 29681789, PMCID: PMC5907923, PII: 10.1007/s11306-017-1311-y, DOI: 10.1007/s11306-017-1311-y, ISSN: 1573-3882.

Tyagi P, Motley SS, Koyama T, Kashyap M, Gingrich J, Yoshimura N, Fowke JH. Molecular correlates in urine for the obesity and prostatic inflammation of BPH/LUTS patients. Prostate [print-electronic]. 2018 Jan; 78(1): 17-24. PMID: 29080225, PMCID: PMC5716834, DOI: 10.1002/pros.23439, ISSN: 1097-0045.

Ark JT, Alvarez JR, Koyama T, Bassett JC, Blot WJ, Mumma MT, Resnick MJ, You C, Penson DF, Barocas DA. Variation in the Diagnostic Evaluation among Persons with Hematuria: Influence of Gender, Race and Risk Factors for Bladder Cancer. J Urol [print-electronic]. 2017 Nov; 198(5): 1033-8. PMID: 28655530, PMCID: PMC5827951, PII: S0022-5347(17)76746-8, DOI: 10.1016/j.juro.2017.06.083, ISSN: 1527-3792.

Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB. External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome. Intensive Care Med [print-electronic]. 2017 Aug; 43(8): 1123-31. PMID: 28593401, PMCID: PMC5978765, PII: 10.1007/s00134-017-4854-5, DOI: 10.1007/s00134-017-4854-5, ISSN: 1432-1238.

Tyson MD, Alvarez J, Koyama T, Hoffman KE, Resnick MJ, Wu XC, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hashibe M, Paddock LE, Stroup A, Chen VW, Penson DF, Barocas DA. Racial Variation in Patient-Reported Outcomes Following Treatment for Localized Prostate Cancer: Results from the CEASAR Study. Eur Urol [print-electronic]. 2017 Aug; 72(2): 307-14. PMID: 27816300, PMCID: PMC5413424, PII: S0302-2838(16)30750-3, DOI: 10.1016/j.eururo.2016.10.036, ISSN: 1873-7560.

Charoenpitakchai M, Liu E, Zhao Z, Koyama T, Huh WJ, Berlin J, Hande K, Walker R, Shi C. In liver metastases from small intestinal neuroendocrine tumors, SSTR2A expression is heterogeneous. Virchows Arch [print-electronic]. 2017 May; 470(5): 545-52. PMID: 28213807, PMCID: PMC5623953, PII: 10.1007/s00428-017-2093-3, DOI: 10.1007/s00428-017-2093-3, ISSN: 1432-2307.

Lang MF, Tyson MD, Alvarez JR, Koyama T, Hoffman KE, Resnick MJ, Cooperberg MR, Wu XC, Chen V, Paddock LE, Hamilton AS, Hashibe M, Goodman M, Greenfield S, Kaplan SH, Stroup A, Penson DF, Barocas DA. The Influence of Psychosocial Constructs on the Adherence to Active Surveillance for Localized Prostate Cancer in a Prospective, Population-based Cohort. Urology [print-electronic]. 2017 May; 103: 173-8. PMID: 28189554, PMCID: PMC5410889, PII: S0090-4295(17)30123-1, DOI: 10.1016/j.urology.2016.12.063, ISSN: 1527-9995.

Luo L, Shaver CM, Zhao Z, Koyama T, Calfee CS, Bastarache JA, Ware LB. Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS. Chest [print-electronic]. 2017 Apr; 151(4): 755-63. PMID: 27663180, PMCID: PMC5472517, PII: S0012-3692(16)59167-3, DOI: 10.1016/j.chest.2016.09.004, ISSN: 1931-3543.

Barocas DA, Alvarez J, Resnick MJ, Koyama T, Hoffman KE, Tyson MD, Conwill R, McCollum D, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hashibe M, Kaplan SH, Paddock LE, Stroup AM, Wu XC, Penson DF. Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. JAMA. 2017 Mar 3/21/2017; 317(11): 1126-40. PMID: 28324093, PMCID: PMC5782813, PII: 2612618, DOI: 10.1001/jama.2017.1704, ISSN: 1538-3598.

Eifler JB, Alvarez J, Koyama T, Conwill RM, Ritch CR, Hoffman KE, Resnick MJ, Penson DF, Barocas DA, . More Judicious Use of Expectant Management for Localized Prostate Cancer during the Last 2 Decades. J Urol [print-electronic]. 2017 Mar; 197(3 Pt 1): 614-20. PMID: 27984110, PMCID: PMC5315642, PII: S0022-5347(16)31611-1, DOI: 10.1016/j.juro.2016.10.067, ISSN: 1527-3792.

Russell DW, Janz DR, Emerson WL, May AK, Bernard GR, Zhao Z, Koyama T, Ware LB. Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries. BMC Pulm Med. 2017 Feb 2/3/2017; 17(1): 29. PMID: 28158980, PMCID: PMC5291954, PII: 10.1186/s12890-017-0370-1, DOI: 10.1186/s12890-017-0370-1, ISSN: 1471-2466.

Rapoport Y, Freeman T, Koyama T, Engelhardt BG, Jagasia M, Savani BN, Tran U, Kassim AA. Validation of International Chronic Ocular Graft-Versus-Host Disease (GVHD) Group Diagnostic Criteria as a Chronic Ocular GVHD-Specific Metric. Cornea. 2017 Feb; 36(2): 258-63. PMID: 28060078, PII: 00003226-201702000-00022, DOI: 10.1097/ICO.0000000000001109, ISSN: 1536-4798.

Goff LW, Cardin DB, Whisenant JG, Du L, Koyama T, Dahlman KB, Salaria SN, Young RT, Ciombor KK, Gilbert J, Smith SJ, Chan E, Berlin J. A phase I trial investigating pulsatile erlotinib in combination with gemcitabine and oxaliplatin in advanced biliary tract cancers. Invest New Drugs [print-electronic]. 2017 Feb; 35(1): 95-104. PMID: 27853997, PMCID: PMC5306261, PII: 10.1007/s10637-016-0406-z, DOI: 10.1007/s10637-016-0406-z, ISSN: 1573-0646.

Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS. Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries. Trauma Surg Acute Care Open. 2017; 2(1): e000121. PMID: 29766112, PMCID: PMC5887582, PII: tsaco-2017-000121, DOI: 10.1136/tsaco-2017-000121, ISSN: 2397-5776.

Abana CO, Bingham BS, Cho JH, Graves AJ, Koyama T, Pilarski RT, Chakravarthy AB, Xia F. IL-6 variant is associated with metastasis in breast cancer patients. PLoS One. 2017; 12(7): e0181725. PMID: 28732081, PMCID: PMC5521838, PII: PONE-D-17-05837, DOI: 10.1371/journal.pone.0181725, ISSN: 1932-6203.

Sohn W, Resnick MJ, Greenfield S, Kaplan SH, Phillips S, Koyama T, Goodman M, Hamilton AS, Hashibe M, Hoffman KE, Paddock LE, Stroup AM, Wu XC, Penson DF, Barocas DA. Impact of Adherence to Quality Measures for Localized Prostate Cancer on Patient-reported Health-related Quality of Life Outcomes, Patient Satisfaction, and Treatment-related Complications. Med Care. 2016 Aug; 54(8): 738-44. PMID: 27219634, PMCID: PMC4945364, DOI: 10.1097/MLR.0000000000000562, ISSN: 1537-1948.

Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 May 5/15/2016; 193(10): 1143-50. PMID: 26681363, PMCID: PMC4872663, DOI: 10.1164/rccm.201507-1418OC, ISSN: 1535-4970.

O'Neil B, Koyama T, Alvarez J, Conwill RM, Albertsen PC, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hoffman KE, Hoffman RM, Kaplan SH, Stanford JL, Stroup AM, Paddock LE, Wu XC, Stephenson RA, Resnick MJ, Barocas DA, Penson DF. The Comparative Harms of Open and Robotic Prostatectomy in Population Based Samples. J Urol [print-electronic]. 2016 Feb; 195(2): 321-9. PMID: 26343985, PMCID: PMC4916911, PII: S0022-5347(15)04712-6, DOI: 10.1016/j.juro.2015.08.092, ISSN: 1527-3792.

Fowke JH, Koyama T, Fadare O, Clark PE. Does Inflammation Mediate the Obesity and BPH Relationship? An Epidemiologic Analysis of Body Composition and Inflammatory Markers in Blood, Urine, and Prostate Tissue, and the Relationship with Prostate Enlargement and Lower Urinary Tract Symptoms. PLoS One. 2016; 11(6): e0156918. PMID: 27336586, PMCID: PMC4918934, PII: PONE-D-16-08801, DOI: 10.1371/journal.pone.0156918, ISSN: 1932-6203.

Archer KR, Devin CJ, Vanston SW, Koyama T, Phillips SE, Mathis SL, George SZ, McGirt MJ, Spengler DM, Aaronson OS, Cheng JS, Wegener ST. Cognitive-Behavioral-Based Physical Therapy for Patients With Chronic Pain Undergoing Lumbar Spine Surgery: A Randomized Controlled Trial. J Pain [print-electronic]. 2016 Jan; 17(1): 76-89. PMID: 26476267, PMCID: PMC4709178, PII: S1526-5900(15)00906-2, DOI: 10.1016/j.jpain.2015.09.013, ISSN: 1528-8447.

Lindell RB, Koh SJ, Alvarez JM, Koyama T, Esbenshade AJ, Simmons JH, Friedman DL. Knowledge of diagnosis, treatment history, and risk of late effects among childhood cancer survivors and parents: The impact of a survivorship clinic. Pediatr Blood Cancer [print-electronic]. 2015 Aug; 62(8): 1444-51. PMID: 25894324, DOI: 10.1002/pbc.25509, ISSN: 1545-5017.

Resnick MJ, Barocas DA, Morgans AK, Phillips SE, Koyama T, Albertsen PC, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hoffman KE, Hoffman RM, Kaplan SH, McCollum D, Paddock LE, Stanford JL, Stroup AM, Wu XC, Penson DF. The Evolution of Self-Reported Urinary and Sexual Dysfunction over the Last Two Decades: Implications for Comparative Effectiveness Research. Eur Urol [print-electronic]. 2015 Jun; 67(6): 1019-25. PMID: 25174325, PMCID: PMC4412750, PII: S0302-2838(14)00788-X, DOI: 10.1016/j.eururo.2014.08.035, ISSN: 1873-7560.

Simon SD, Koyama T, Zacharia BE, Schirmer CM, Cheng JS. Impact of clinical trials on neurosurgical practice: an assessment of case volume. World Neurosurg [print-electronic]. 2015 Apr; 83(4): 431-7. PMID: 25655690, PII: S1878-8750(15)00033-9, DOI: 10.1016/j.wneu.2015.01.011, ISSN: 1878-8769.

Bassett JC, Alvarez J, Koyama T, Resnick M, You C, Ni S, Penson DF, Barocas DA. Gender, race, and variation in the evaluation of microscopic hematuria among Medicare beneficiaries. J Gen Intern Med [print-electronic]. 2015 Apr; 30(4): 440-7. PMID: 25451992, PMCID: PMC4371014, DOI: 10.1007/s11606-014-3116-2, ISSN: 1525-1497.

Morgans AK, Fan KH, Koyama T, Albertsen PC, Goodman M, Hamilton AS, Hoffman RM, Stanford JL, Stroup AM, Resnick MJ, Barocas DA, Penson DF. Influence of age on incident diabetes and cardiovascular disease in prostate cancer survivors receiving androgen deprivation therapy. J Urol [print-electronic]. 2015 Apr; 193(4): 1226-31. PMID: 25451829, PMCID: PMC4542148, PII: S0022-5347(14)04835-6, DOI: 10.1016/j.juro.2014.11.006, ISSN: 1527-3792.

Tsugawa D, Fukumoto T, Kido M, Takebe A, Tanaka M, Kuramitsu K, Matsumoto I, Ajiki T, Koyama T, Ku Y. The Predictive Power of Serum a-Fetoprotein and Des-¿-Carboxy Prothrombin for Survival Varies by Tumor Size in Hepatocellular Carcinoma. Kobe J Med Sci. 2015 Mar 3/7/2015; 61(5): E124-31. PMID: 27363395, ISSN: 1883-0498.

Samuelson LE, Scherer RL, VanSaun MN, Fan KH, Dozier EA, Carter KJ, Koyama T, Shyr Y, Aschner M, Stanwood GD, Bornhop DJ, Matrisian LM, McIntyre JO. New tools for the quantitative assessment of prodrug delivery and neurotoxicity. Neurotoxicology [print-electronic]. 2015 Mar; 47: 88-98. PMID: 25732874, PMCID: PMC4501381, PII: S0161-813X(15)00023-6, DOI: 10.1016/j.neuro.2015.02.005, ISSN: 1872-9711.

Shi C, Gonzalez RS, Zhao Z, Koyama T, Cornish TC, Hande KR, Walker R, Sandler M, Berlin J, Liu EH. Liver metastases of small intestine neuroendocrine tumors: Ki-67 heterogeneity and World Health Organization grade discordance with primary tumors. Am J Clin Pathol. 2015 Mar; 143(3): 398-404. PMID: 25696798, PMCID: PMC4354931, PII: 143/3/398, DOI: 10.1309/AJCPQ55SKOCYFZHN, ISSN: 1943-7722.

Daskivich TJ, Fan KH, Koyama T, Albertsen PC, Goodman M, Hamilton AS, Hoffman RM, Stanford JL, Stroup AM, Litwin MS, Penson DF. Prediction of long-term other-cause mortality in men with early-stage prostate cancer: results from the Prostate Cancer Outcomes Study. Urology [print-electronic]. 2015 Jan; 85(1): 92-100. PMID: 25261048, PMCID: PMC4275422, PII: S0090-4295(14)00703-1, DOI: 10.1016/j.urology.2014.07.003, ISSN: 1527-9995.

Morgans AK, Fan KH, Koyama T, Albertsen PC, Goodman M, Hamilton AS, Hoffman RM, Stanford JL, Stroup AM, Penson DF. Bone complications among prostate cancer survivors: long-term follow-up from the prostate cancer outcomes study. Prostate Cancer Prostatic Dis [print-electronic]. 2014 Dec; 17(4): 338-42. PMID: 25134939, PMCID: PMC4227957, PII: pcan201431, DOI: 10.1038/pcan.2014.31, ISSN: 1476-5608.

Snyder RA, Penson DF, Ni S, Koyama T, Merchant NB. Trends in the use of evidence-based therapy for resectable gastric cancer. J Surg Oncol [print-electronic]. 2014 Sep; 110(3): 285-90. PMID: 24891231, PMCID: PMC4260801, DOI: 10.1002/jso.23635, ISSN: 1096-9098.

Bastarache JA, Koyama T, Wickersham NE, Ware LB. Validation of a multiplex electrochemiluminescent immunoassay platform in human and mouse samples. J Immunol Methods [print-electronic]. 2014 Jun; 408: 13-23. PMID: 24768796, PMCID: PMC4120713, PII: S0022-1759(14)00123-9, DOI: 10.1016/j.jim.2014.04.006, ISSN: 1872-7905.

Jin R, Yi Y, Yull FE, Blackwell TS, Clark PE, Koyama T, Smith JA, Matusik RJ. NF-¿B gene signature predicts prostate cancer progression. Cancer Res [print-electronic]. 2014 May 5/15/2014; 74(10): 2763-72. PMID: 24686169, PMCID: PMC4024337, PII: 0008-5472.CAN-13-2543, DOI: 10.1158/0008-5472.CAN-13-2543, ISSN: 1538-7445.

Resnick MJ, Barocas DA, Morgans AK, Phillips SE, Chen VW, Cooperberg MR, Goodman M, Greenfield S, Hamilton AS, Hoffman KE, Kaplan SH, Paddock LE, Stroup AM, Wu XC, Koyama T, Penson DF. Contemporary prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction: Defining the population at risk for harms of prostate cancer treatment. Cancer [print-electronic]. 2014 Apr 4/15/2014; 120(8): 1263-71. PMID: 24510400, PMCID: PMC4930672, DOI: 10.1002/cncr.28563, ISSN: 1097-0142.

Barocas DA, Alvarez J, Koyama T, Anderson CB, Gray DT, Fowke JH, You C, Chang SS, Cookson MS, Smith JA, Penson DF. Racial variation in the quality of surgical care for bladder cancer. Cancer [print-electronic]. 2014 Apr 4/1/2014; 120(7): 1018-25. PMID: 24339051, PMCID: PMC3961490, DOI: 10.1002/cncr.28520, ISSN: 1097-0142.

Barnett N, Zhao Z, Koyama T, Janz DR, Wang CY, May AK, Bernard GR, Ware LB. Vitamin D deficiency and risk of acute lung injury in severe sepsis and severe trauma: a case-control study. Ann Intensive Care. 2014 Feb 2/24/2014; 4(1): 5. PMID: 24559079, PMCID: PMC3944729, PII: 2110-5820-4-5, DOI: 10.1186/2110-5820-4-5, ISSN: 2110-5820.

Chen Q, Wu H, Ware LB, Koyama T. A Bayesian Approach for the Cox Proportional Hazards Model with Covariates Subject to Detection Limit. Int J Stat Med Res. 2014 Jan 1/31/2014; 3(1): 32-43. PMID: 24772198, PMCID: PMC3998726, DOI: 10.6000/1929-6029.2014.03.01.5, ISSN: 1929-6029.

Weitkamp JH, Rosen MJ, Zhao Z, Koyama T, Geem D, Denning TL, Rock MT, Moore DJ, Halpern MD, Matta P, Denning PW. Small intestinal intraepithelial TCR¿d+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis. PLoS One. 2014; 9(6): e99042. PMID: 24905458, PMCID: PMC4048281, PII: PONE-D-14-10885, DOI: 10.1371/journal.pone.0099042, ISSN: 1932-6203.

Pallavaram S, Phibbs FT, Tolleson C, Davis TL, Fang J, Hedera P, Li R, Koyama T, Dawant BM, D'Haese PF. Neurologist consistency in interpreting information provided by an interactive visualization software for deep brain stimulation postoperative programming assistance. Neuromodulation [print-electronic]. 2014 Jan; 17(1): 11-5; discussion 15. PMID: 23647701, PMCID: PMC4039015, PII: S1094-7159(14)60026-X, DOI: 10.1111/ner.12061, ISSN: 1525-1403.

Simmons J, Sheedy C, Lee H, Koh S, Alvarez J, Koyama T, Friedman D. Prevalence of 25-hydroxyvitamin D deficiency in child and adolescent patients undergoing hematopoietic cell transplantation compared to a healthy population. Pediatr Blood Cancer [print-electronic]. 2013 Dec; 60(12): 2025-30. PMID: 23868793, DOI: 10.1002/pbc.24684, ISSN: 1545-5017.

Parikh AA, Ni S, Koyama T, Pawlik TM, Penson D. Trends in the multimodality treatment of resectable colorectal liver metastases: an underutilized strategy. J Gastrointest Surg [print-electronic]. 2013 Nov; 17(11): 1938-46. PMID: 24018590, DOI: 10.1007/s11605-013-2325-z, ISSN: 1873-4626.

Janz DR, Zhao Z, Koyama T, May AK, Bernard GR, Bastarache JA, Young PP, Ware LB. Longer storage duration of red blood cells is associated with an increased risk of acute lung injury in patients with sepsis. Ann Intensive Care. 2013 Sep 9/24/2013; 3(1): 33. PMID: 24059842, PMCID: PMC3848804, PII: 2110-5820-3-33, DOI: 10.1186/2110-5820-3-33, ISSN: 2110-5820.

Esbenshade AJ, Simmons JH, Koyama T, Lindell RB, Friedman DL. Obesity and insulin resistance in pediatric acute lymphoblastic leukemia worsens during maintenance therapy. Pediatr Blood Cancer [print-electronic]. 2013 Aug; 60(8): 1287-91. PMID: 23444342, PMCID: PMC3881979, DOI: 10.1002/pbc.24489, ISSN: 1545-5017.

Barocas DA, Chen V, Cooperberg M, Goodman M, Graff JJ, Greenfield S, Hamilton A, Hoffman K, Kaplan S, Koyama T, Morgans A, Paddock LE, Phillips S, Resnick MJ, Stroup A, Wu XC, Penson DF. Using a population-based observational cohort study to address difficult comparative effectiveness research questions: the CEASAR study. J Comp Eff Res. 2013 Jul; 2(4): 445-60. PMID: 24236685, PMCID: PMC4920086, DOI: 10.2217/cer.13.34, ISSN: 2042-6313.

Edwards HD, Oakley F, Koyama T, Hameed O. The impact of tumor size in breast needle biopsy material on final pathologic size and tumor stage: a detailed analysis of 222 consecutive cases. Am J Surg Pathol. 2013 May; 37(5): 739-44. PMID: 23552386, DOI: 10.1097/PAS.0b013e31828c63d0, ISSN: 1532-0979.

Resnick MJ, Koyama T, Fan KH, Albertsen PC, Goodman M, Hamilton AS, Hoffman RM, Potosky AL, Stanford JL, Stroup AM, Van Horn RL, Penson DF. Long-term functional outcomes after treatment for localized prostate cancer. N Engl J Med. 2013 Jan 1/31/2013; 368(5): 436-45. PMID: 23363497, PMCID: PMC3742365, DOI: 10.1056/NEJMoa1209978, ISSN: 1533-4406.

Fowke JH, Phillips S, Koyama T, Byerly S, Concepcion R, Motley SS, Clark PE. Association between physical activity, lower urinary tract symptoms (LUTS) and prostate volume. BJU Int [print-electronic]. 2013 Jan; 111(1): 122-8. PMID: 22726636, PMCID: PMC3460041, DOI: 10.1111/j.1464-410X.2012.11287.x, ISSN: 1464-410X.

Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB. Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios. Gut [print-electronic]. 2013 Jan; 62(1): 73-82. PMID: 22267598, PMCID: PMC3606820, PII: gutjnl-2011-301551, DOI: 10.1136/gutjnl-2011-301551, ISSN: 1468-3288.

Martinez JA, Koyama T, Acra S, Mascarenhas MR, Shulman RJ. Nutrition education for pediatric gastroenterology, hepatology, and nutrition fellows: survey of NASPGHAN fellowship training programs. J Pediatr Gastroenterol Nutr. 2012 Aug; 55(2): 131-5. PMID: 22343911, PMCID: PMC3395733, DOI: 10.1097/MPG.0b013e31824ee535, ISSN: 1536-4801.

Korhonen K, Lovvorn HN, Koyama T, Koehler E, Calder C, Manes B, Evans M, Bruce K, Ho RH, Domm J, Frangoul H. Incidence, risk factors, and outcome of pneumatosis intestinalis in pediatric stem cell transplant recipients. Pediatr Blood Cancer [print-electronic]. 2012 Apr; 58(4): 616-20. PMID: 21721114, DOI: 10.1002/pbc.23242, ISSN: 1545-5017.

Wu H, Chen Q, Ware LB, Koyama T. A Bayesian Approach for Generalized Linear Models with Explanatory Biomarker Measurement Variables Subject to Detection Limit - an Application to Acute Lung Injury. J Appl Stat [print-electronic]. 2012; 39(8): 1733-47. PMID: 23049157, PMCID: PMC3463110, DOI: 10.1080/02664763.2012.681362, ISSN: 0266-4763.

Smith DS, Welch EB, Li X, Arlinghaus LR, Loveless ME, Koyama T, Gore JC, Yankeelov TE. Quantitative effects of using compressed sensing in dynamic contrast enhanced MRI. Phys Med Biol [print-electronic]. 2011 Aug 8/7/2011; 56(15): 4933-46. PMID: 21772079, PMCID: PMC3192434, PII: S0031-9155(11)83500-1, DOI: 10.1088/0031-9155/56/15/018, ISSN: 1361-6560.

Deeley MA, Chen A, Datteri R, Noble JH, Cmelak AJ, Donnelly EF, Malcolm AW, Moretti L, Jaboin J, Niermann K, Yang ES, Yu DS, Yei F, Koyama T, Ding GX, Dawant BM. Comparison of manual and automatic segmentation methods for brain structures in the presence of space-occupying lesions: a multi-expert study. Phys Med Biol [print-electronic]. 2011 Jul 7/21/2011; 56(14): 4557-77. PMID: 21725140, PMCID: PMC3153124, PII: S0031-9155(11)85448-5, DOI: 10.1088/0031-9155/56/14/021, ISSN: 1361-6560.

Ware LB, Koyama T, Billheimer D, Landeck M, Johnson E, Brady S, Bernard GR, Matthay MA, . Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial. Ann Intensive Care. 2011 Jun 6/14/2011; 1(1): 20. PMID: 21906362, PMCID: PMC3224478, PII: 2110-5820-1-20, DOI: 10.1186/2110-5820-1-20, ISSN: 2110-5820.

Williams K, Koyama T, Schulz D, Kaluza GL, Pautler RG, Weisbrodt N, Conner ME. Use of fluoroscopy to study in vivo motility in mouse pups. J Pediatr Gastroenterol Nutr. 2011 Jun; 52(6): 679-85. PMID: 21593642, PMCID: PMC3098421, PII: 00005176-201106000-00007, DOI: 10.1097/MPG.0b013e31820a0e86, ISSN: 1536-4801.

Bastarache JA, Koyama T, Wickersham NE, Mitchell DB, Mernaugh RL, Ware LB. Accuracy and reproducibility of a multiplex immunoassay platform: a validation study. J Immunol Methods [print-electronic]. 2011 Mar 3/31/2011; 367(1-2): 33-9. PMID: 21277854, PMCID: PMC3108329, PII: S0022-1759(11)00008-1, DOI: 10.1016/j.jim.2011.01.005, ISSN: 1872-7905.

Esbenshade AJ, Simmons JH, Koyama T, Koehler E, Whitlock JA, Friedman DL. Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer. 2011 Mar; 56(3): 372-8. PMID: 20860019, PMCID: PMC3713225, DOI: 10.1002/pbc.22782, ISSN: 1545-5017.

Mukherjee K, Peng D, Brifkani Z, Belkhiri A, Pera M, Koyama T, Koehler EA, Revetta FL, Washington MK, El-Rifai W. Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis. Surgery [print-electronic]. 2010 Aug; 148(2): 354-63. PMID: 20580047, PMCID: PMC2919779, PII: S0039-6060(10)00274-6, DOI: 10.1016/j.surg.2010.05.011, ISSN: 1532-7361.

Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, May AK, Ware LB. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma. 2010 May; 68(5): 1121-7. PMID: 20038857, PMCID: PMC3347639, DOI: 10.1097/TA.0b013e3181c40728, ISSN: 1529-8809.

Rosen MJ, Moulton DE, Koyama T, Morgan WM, Morrow SE, Herline AJ, Muldoon RL, Wise PE, Polk DB, Schwartz DA. Endoscopic ultrasound to guide the combined medical and surgical management of pediatric perianal Crohn's disease. Inflamm Bowel Dis. 2010 Mar; 16(3): 461-8. PMID: 19637325, PMCID: PMC2871764, DOI: 10.1002/ibd.21067, ISSN: 1536-4844.

Ware LB, Koyama T, Billheimer DD, Wu W, Bernard GR, Thompson BT, Brower RG, Standiford TJ, Martin TR, Matthay MA, . Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest [print-electronic]. 2010 Feb; 137(2): 288-96. PMID: 19858233, PMCID: PMC2816641, PII: S0012-3692(10)60070-0, DOI: 10.1378/chest.09-1484, ISSN: 1931-3543.

Love HD, Booton SE, Boone BE, Breyer JP, Koyama T, Revelo MP, Shappell SB, Smith JR, Hayward SW. Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer. PLoS One. 2009 Dec 12/21/2009; 4(12): e8384. PMID: 20027305, PMCID: PMC2793011, DOI: 10.1371/journal.pone.0008384, ISSN: 1932-6203.

Sisler IY, Koehler E, Koyama T, Domm JA, Ryan R, Levine JE, Pulsipher MA, Haut PR, Schultz KR, Taylor DS, Frangoul HA. Impact of conditioning regimen in allogeneic hematopoetic stem cell transplantation for children with acute myelogenous leukemia beyond first complete remission: a pediatric blood and marrow transplant consortium (PBMTC) study. Biol Blood Marrow Transplant [print-electronic]. 2009 Dec; 15(12): 1620-7. PMID: 19896086, PII: S1083-8791(09)00394-2, DOI: 10.1016/j.bbmt.2009.08.014, ISSN: 1523-6536.

Weitkamp JH, Rudzinski E, Koyama T, Correa H, Matta P, Alberty B, Polk DB. Ontogeny of FOXP3(+) regulatory T cells in the postnatal human small intestinal and large intestinal lamina propria. Pediatr Dev Pathol. 2009 Nov; 12(6): 443-9. PMID: 19203136, PMCID: PMC2844857, PII: 08-09-0533, DOI: 10.2350/08-09-0533.1, ISSN: 1093-5266.

Pallavaram S, Dawant BM, Koyama T, Yu H, Neimat J, Konrad PE, D'Haese PF. Validation of a fully automatic method for the routine selection of the anterior and posterior commissures in magnetic resonance images. Stereotact Funct Neurosurg [print-electronic]. 2009; 87(3): 148-54. PMID: 19321967, PMCID: PMC2835380, PII: 000209295, DOI: 10.1159/000209295, ISSN: 1423-0372.

Piro CC, Crossno CL, Collier A, Ho R, Koyama T, Frangoul H. Initial vancomycin dosing in pediatric oncology and stem cell transplant patients. J Pediatr Hematol Oncol. 2009 Jan; 31(1): 3-7. PMID: 19125078, PII: 00043426-200901000-00002, DOI: 10.1097/MPH.0b013e31818b3520, ISSN: 1536-3678.

Blum DL, Koyama T, M'Koma AE, Iturregui JM, Martinez-Ferrer M, Uwamariya C, Smith JA, Clark PE, Bhowmick NA. Chemokine markers predict biochemical recurrence of prostate cancer following prostatectomy. Clin Cancer Res. 2008 Dec 12/1/2008; 14(23): 7790-7. PMID: 19047106, PMCID: PMC3050736, PII: 14/23/7790, DOI: 10.1158/1078-0432.CCR-08-1716, ISSN: 1078-0432.

Li X, Placencio V, Iturregui JM, Uwamariya C, Sharif-Afshar AR, Koyama T, Hayward SW, Bhowmick NA. Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis. Oncogene [print-electronic]. 2008 Nov 11/27/2008; 27(56): 7118-30. PMID: 18724388, PMCID: PMC3222150, PII: onc2008293, DOI: 10.1038/onc.2008.293, ISSN: 1476-5594.

Edelblum KL, Goettel JA, Koyama T, McElroy SJ, Yan F, Polk DB. TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. J Biol Chem [print-electronic]. 2008 Oct 10/24/2008; 283(43): 29485-94. PMID: 18713739, PMCID: PMC2570867, PII: S0021-9258(20)64178-3, DOI: 10.1074/jbc.M801269200, ISSN: 0021-9258.

Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB. Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB. Gastroenterology [print-electronic]. 2008 Aug; 135(2): 539-51. PMID: 18598699, PMCID: PMC2640938, PII: S0016-5085(08)00720-8, DOI: 10.1053/j.gastro.2008.04.025, ISSN: 1528-0012.

Koyama T, Chen H. Proper inference from Simon's two-stage designs. Stat Med. 2008 Jul 7/20/2008; 27(16): 3145-54. PMID: 17960777, PMCID: PMC6047527, DOI: 10.1002/sim.3123, ISSN: 0277-6715.

Kawaguchi M, Hager HA, Wada A, Koyama T, Chang MS, Bader DM. Identification of a novel intracellular interaction domain essential for Bves function. PLoS One. 2008 May 5/21/2008; 3(5): e2261. PMID: 18493308, PMCID: PMC2373926, DOI: 10.1371/journal.pone.0002261, ISSN: 1932-6203.

Dar AA, Zaika A, Piazuelo MB, Correa P, Koyama T, Belkhiri A, Washington K, Castells A, Pera M, El-Rifai W. Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions. Cancer. 2008 Apr 4/15/2008; 112(8): 1688-98. PMID: 18311783, PMCID: PMC4030394, DOI: 10.1002/cncr.23371, ISSN: 0008-543X.

Branner CM, Koyama T, Jensen GL. Racial and ethnic differences in pediatric obesity-prevention counseling: national prevalence of clinician practices. Obesity (Silver Spring) [print-electronic]. 2008 Mar; 16(3): 690-4. PMID: 18239563, PII: oby200778, DOI: 10.1038/oby.2007.78, ISSN: 1930-7381.

Koyama T. Flexible design of two-stage adaptive procedures for phase III clinical trials. Contemp Clin Trials [print-electronic]. 2007 Jul; 28(4): 500-13. PMID: 17307399, PII: S1551-7144(07)00009-2, DOI: 10.1016/j.cct.2007.01.007, ISSN: 1551-7144.

Sepmeyer JA, Greer JP, Koyama T, Zic JA. Open-label pilot study of combination therapy with rosiglitazone and bexarotene in the treatment of cutaneous T-cell lymphoma. J Am Acad Dermatol [print-electronic]. 2007 Apr; 56(4): 584-7. PMID: 17184879, PII: S0190-9622(06)02865-9, DOI: 10.1016/j.jaad.2006.10.033, ISSN: 1097-6787.

Jones E, Koyama T, Ho RH, Kuttesch J, Shankar S, Whitlock JA, Cartwright J, Frangoul H. Safety and efficacy of a continuous infusion, patient-controlled antiemetic pump for children receiving emetogenic chemotherapy. Pediatr Blood Cancer. 2007 Mar; 48(3): 330-2. PMID: 16304666, DOI: 10.1002/pbc.20711, ISSN: 1545-5009.

M'Koma AE, Blum DL, Norris JL, Koyama T, Billheimer D, Motley S, Ghiassi M, Ferdowsi N, Bhowmick I, Chang SS, Fowke JH, Caprioli RM, Bhowmick NA. Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine. Biochem Biophys Res Commun [print-electronic]. 2007 Feb 2/16/2007; 353(3): 829-34. PMID: 17194448, PMCID: PMC2562600, PII: S0006-291X(06)02787-2, DOI: 10.1016/j.bbrc.2006.12.111, ISSN: 0006-291X.

Keates-Baleeiro J, Moore P, Koyama T, Manes B, Calder C, Frangoul H. Incidence and outcome of idiopathic pneumonia syndrome in pediatric stem cell transplant recipients. Bone Marrow Transplant [print-electronic]. 2006 Aug; 38(4): 285-9. PMID: 16819436, PII: 1705436, DOI: 10.1038/sj.bmt.1705436, ISSN: 0268-3369.

Koyama T, Sampson AR, Gleser LJ. A framework for two-stage adaptive procedures to simultaneously test non-inferiority and superiority. Stat Med. 2005 Aug 8/30/2005; 24(16): 2439-56. PMID: 15977285, DOI: 10.1002/sim.2118, ISSN: 0277-6715.

Schwartz DA, Connolley CD, Koyama T, Wise PE, Herline AJ. Calcaneal ultrasound bone densitometry is not a useful tool to screen patients with inflammatory bowel disease at high risk for metabolic bone disease. Inflamm Bowel Dis. 2005 Aug; 11(8): 749-54. PMID: 16043991, PII: 00054725-200508000-00008, DOI: 10.1097/01.mib.0000172809.11501.f4, ISSN: 1078-0998.

Rhodes M, Lautz T, Kavanaugh-Mchugh A, Manes B, Calder C, Koyama T, Liske M, Parra D, Frangoul H. Pericardial effusion and cardiac tamponade in pediatric stem cell transplant recipients. Bone Marrow Transplant. 2005 Jul; 36(2): 139-44. PMID: 15908968, PII: 1705023, DOI: 10.1038/sj.bmt.1705023, ISSN: 0268-3369.

Koyama T, Westfall PH. Decision-theoretic views on simultaneous testing of superiority and noninferiority. J Biopharm Stat. 2005; 15(6): 943-55. PMID: 16279353, DOI: 10.1080/10543400500265694, ISSN: 1054-3406.

Layman W, Koyama T. A clinical comparison of LED and halogen curing units. J Clin Orthod. 2004 Jul; 38(7): 385-7. PMID: 15304953, ISSN: 0022-3875.