Jing Zhou, Ph.D.

Research Assistant Professor

Faculty Appointments
Research Assistant Professor of Pathology, Microbiology and Immunology
Ph.D., Chinese Academy of Sciences, Beijing, ChinaB.S., Ocean University of China, Qingdao, ChinaM.S., Chinese Academy of Sciences, Beijing, China
Office Address
AA5230 MCN
TN 2363
Hill KE, Zhou J, Austin LM, Motley AK, Ham AJ, Olson GE, Atkins JF, Gesteland RF, Burk RF. The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body selenium. J. Biol. Chem [print-electronic]. 2007 Apr 4/13/2007; 282(15): 10972-80. PMID: 17311913, PII: M700436200, DOI: 10.1074/jbc.M700436200, ISSN: 0021-9258.

Zhou J, Chen CH, Aiken C. Human immunodeficiency virus type 1 resistance to the small molecule maturation inhibitor 3-O-(3',3'-dimethylsuccinyl)-betulinic acid is conferred by a variety of single amino acid substitutions at the CA-SP1 cleavage site in Gag. J. Virol [print-electronic]. 2006 Dec; 80(24): 12095-101. PMID: 17035324, PMCID: PMC1676313, PII: JVI.01626-06, DOI: 10.1128/JVI.01626-06, ISSN: 0022-538X.

Hallaq H, Yang Z, Viswanathan PC, Fukuda K, Shen W, Wang DW, Wells KS, Zhou J, Yi J, Murray KT. Quantitation of protein kinase A-mediated trafficking of cardiac sodium channels in living cells. Cardiovasc. Res [print-electronic]. 2006 Nov 11/1/2006; 72(2): 250-61. PMID: 16973141, PII: S0008-6363(06)00382-8, DOI: 10.1016/j.cardiores.2006.08.007, ISSN: 0008-6363.

Davis MR, Jiang J, Zhou J, Freed EO, Aiken C. A mutation in the human immunodeficiency virus type 1 Gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41. J. Virol. 2006 Mar; 80(5): 2405-17. PMID: 16474147, PMCID: PMC1395406, PII: 80/5/2405, DOI: 10.1128/JVI.80.5.2405-2417.2006, ISSN: 0022-538X.

Zhou J, Huang L, Hachey DL, Chen CH, Aiken C. Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles. J. Biol. Chem [print-electronic]. 2005 Dec 12/23/2005; 280(51): 42149-55. PMID: 16251182, PII: M508951200, DOI: 10.1074/jbc.M508951200, ISSN: 0021-9258.

Kar A, Kuo D, He R, Zhou J, Wu JY. Tau alternative splicing and frontotemporal dementia. Alzheimer Dis Assoc Disord. 2005 Oct; 19 Suppl 1: S29-36. PMID: 16317255, PMCID: PMC2001171, PII: 00002093-200510001-00007, ISSN: 0893-0341.

Lundquist CA, Zhou J, Aiken C. Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication. J. Virol. 2004 Jun; 78(12): 6287-96. PMID: 15163722, PMCID: PMC416500, PII: 78/12/6287, DOI: 10.1128/JVI.78.12.6287-6296.2004, ISSN: 0022-538X.

Wyma DJ, Jiang J, Shi J, Zhou J, Lineberger JE, Miller MD, Aiken C. Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tail. J. Virol. 2004 Apr; 78(7): 3429-35. PMID: 15016865, PMCID: PMC371074, ISSN: 0022-538X.

Zhou J, Chen CH, Aiken C. The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid. Retrovirology. 2004; 1: 15. PMID: 15225375, PMCID: PMC479704, PII: 1742-4690-1-15, DOI: 10.1186/1742-4690-1-15, ISSN: 1742-4690.

Hill KE, Zhou J, McMahan WJ, Motley AK, Burk RF. Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene. J. Nutr. 2004 Jan; 134(1): 157-61. PMID: 14704310, ISSN: 0022-3166.

Zhou J, Yuan X, Dismuke D, Forshey BM, Lundquist C, Lee KH, Aiken C, Chen CH. Small-molecule inhibition of human immunodeficiency virus type 1 replication by specific targeting of the final step of virion maturation. J. Virol. 2004 Jan; 78(2): 922-9. PMID: 14694123, PMCID: PMC368845, ISSN: 0022-538X.

Hill KE, Zhou J, McMahan WJ, Motley AK, Atkins JF, Gesteland RF, Burk RF. Deletion of selenoprotein P alters distribution of selenium in the mouse. J. Biol. Chem [print-electronic]. 2003 Apr 4/18/2003; 278(16): 13640-6. PMID: 12574155, PII: M300755200, DOI: 10.1074/jbc.M300755200, ISSN: 0021-9258.

Zhou J, Shin HG, Yi J, Shen W, Williams CP, Murray KT. Phosphorylation and putative ER retention signals are required for protein kinase A-mediated potentiation of cardiac sodium current. Circ. Res. 2002 Sep 9/20/2002; 91(6): 540-6. PMID: 12242273, ISSN: 1524-4571.

Lundquist CA, Tobiume M, Zhou J, Unutmaz D, Aiken C. Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. J. Virol. 2002 May; 76(9): 4625-33. PMID: 11932428, PMCID: PMC155097, ISSN: 0022-538X.

Zhou J, Aiken C. Nef enhances human immunodeficiency virus type 1 infectivity resulting from intervirion fusion: evidence supporting a role for Nef at the virion envelope. J. Virol. 2001 Jul; 75(13): 5851-9. PMID: 11390586, PMCID: PMC114300, DOI: 10.1128/JVI.75.13.5851-5859.2001, ISSN: 0022-538X.

Zhou J, Yi J, Hu N, George AL, Murray KT. Activation of protein kinase A modulates trafficking of the human cardiac sodium channel in Xenopus oocytes. Circ. Res. 2000 Jul 7/7/2000; 87(1): 33-8. PMID: 10884369, ISSN: 0009-7330.

Kotov A, Zhou J, Flicker P, Aiken C. Association of Nef with the human immunodeficiency virus type 1 core. J. Virol. 1999 Oct; 73(10): 8824-30. PMID: 10482638, PMCID: PMC112905, ISSN: 0022-538X.

Zhou J, Cribbs L, Yi J, Shirokov R, Perez-Reyes E, RĂ­os E. Molecular cloning and functional expression of a skeletal muscle dihydropyridine receptor from Rana catesbeiana. J. Biol. Chem. 1998 Sep 9/25/1998; 273(39): 25503-9. PMID: 9738021, ISSN: 0021-9258.

Montefiori DC, Graham BS, Zhou J, Zhou J, Bucco RA, Schwartz DH, Cavacini LA, Posner MR. V3-specific neutralizing antibodies in sera from HIV-1 gp160-immunized volunteers block virus fusion and act synergistically with human monoclonal antibody to the conformation-dependent CD4 binding site of gp120. NIH-NIAID AIDS Vaccine Clinical Trials Network. J. Clin. Invest. 1993 Aug; 92(2): 840-7. PMID: 8349820, PMCID: PMC294922, DOI: 10.1172/JCI116658, ISSN: 0021-9738.

Montefiori DC, Stewart K, Ahearn JM, Zhou J, Zhou J. Complement-mediated binding of naturally glycosylated and glycosylation-modified human immunodeficiency virus type 1 to human CR2 (CD21). J. Virol. 1993 May; 67(5): 2699-706. PMID: 8474169, PMCID: PMC237592, ISSN: 0022-538X.

Montefiori DC, Zhou J, Shaff DI. CD4-independent binding of HIV-1 to the B lymphocyte receptor CR2 (CD21) in the presence of complement and antibody. Clin. Exp. Immunol. 1992 Dec; 90(3): 383-9. PMID: 1360879, PMCID: PMC1554591, ISSN: 0009-9104.

Montefiori DC, Zhou JY. Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro. Antiviral Res. 1991 Jan; 15(1): 11-25. PMID: 1709802, ISSN: 0166-3542.

Montefiori DC, Modliszewski A, Shaff DI, Zhou J. Inhibition of human immunodeficiency virus type 1 replication and cytopathicity by synthetic soluble catecholamine melanins in vitro. Biochem. Biophys. Res. Commun. 1990 Apr 4/16/1990; 168(1): 200-5. PMID: 2327999, PII: 0006-291X(90)91694-N, ISSN: 0006-291X.