Ruth Ann Veach

Research Instructor

ruth.ann.veach@vanderbilt.edu
Faculty Appointments
Research Instructor in Medicine
Education
B.S., Wake Forest University, Winston-Salem, North Carolina
Office Address
A-5301 MCN
TN 2363
Publications
Hawiger J, Veach RA, Zienkiewicz J. New paradigms in sepsis: from prevention to protection of failing microcirculation. J. Thromb. Haemost [print-electronic]. 2015 Oct; 13(10): 1743-56. PMID: 26190521, DOI: 10.1111/jth.13061, ISSN: 1538-7836.

Qiao H, Liu Y, Veach RA, Wylezinski L, Hawiger J. The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli. J. Biol. Chem [print-electronic]. 2014 Aug 8/8/2014; 289(32): 21973-83. PMID: 24958727, PMCID: PMC4139214, PII: M114.588723, DOI: 10.1074/jbc.M114.588723, ISSN: 1083-351X.

DiGiandomenico A, Veach RA, Zienkiewicz J, Moore DJ, Wylezinski LS, Hutchens MA, Hawiger J. The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation. PLoS ONE. 2014; 9(10): e110183. PMID: 25329889, PMCID: PMC4203769, PII: PONE-D-14-26863, DOI: 10.1371/journal.pone.0110183, ISSN: 1932-6203.

Liu Y, Major AS, Zienkiewicz J, Gabriel CL, Veach RA, Moore DJ, Collins RD, Hawiger J. Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver. J Am Heart Assoc. 2013 Apr; 2(2): e000093. PMID: 23563994, PMCID: PMC3647260, PII: 2/2/e000093, DOI: 10.1161/JAHA.113.000093, ISSN: 2047-9980.

Lin Q, Liu Y, Moore DJ, Elizer SK, Veach RA, Hawiger J, Ruley HE. Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. J. Immunol [print-electronic]. 2012 Mar 3/15/2012; 188(6): 2493-7. PMID: 22323537, PMCID: PMC3294148, PII: jimmunol.1101502, DOI: 10.4049/jimmunol.1101502, ISSN: 1550-6606.

Veach RA, Zienkiewicz J, Collins RD, Hawiger J. Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy. PLoS ONE [print-electronic]. 2012; 7(1): e30527. PMID: 22291977, PMCID: PMC3266913, PII: PONE-D-11-13071, DOI: 10.1371/journal.pone.0030527, ISSN: 1932-6203.

Moore DJ, Zienkiewicz J, Kendall PL, Liu D, Liu X, Veach RA, Collins RD, Hawiger J. In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. PLoS ONE. 2010; 5(10): e13235. PMID: 20949090, PMCID: PMC2950856, DOI: 10.1371/journal.pone.0013235, ISSN: 1932-6203.

Liu D, Liu XY, Robinson D, Burnett C, Jackson C, Seele L, Veach RA, Downs S, Collins RD, Ballard DW, Hawiger J. Suppression of Staphylococcal Enterotoxin B-induced Toxicity by a Nuclear Import Inhibitor. J. Biol. Chem [print-electronic]. 2004 Apr 4/30/2004; 279(18): 19239-46. PMID: 14732709, PII: M313442200, DOI: 10.1074/jbc.M313442200, ISSN: 0021-9258.

Veach RA, Liu D, Yao S, Chen Y, Liu XY, Downs S, Hawiger J. Receptor/transporter-independent targeting of functional peptides across the plasma membrane. J. Biol. Chem [print-electronic]. 2004 Mar 3/19/2004; 279(12): 11425-31. PMID: 14699109, PII: M311089200, DOI: 10.1074/jbc.M311089200, ISSN: 0021-9258.

Liu XY, Robinson D, Veach RA, Liu D, Timmons S, Collins RD, Hawiger J. Peptide-directed suppression of a pro-inflammatory cytokine response. J. Biol. Chem. 2000 Jun 6/2/2000; 275(22): 16774-8. PMID: 10751381, PII: C000083200, DOI: 10.1074/jbc.C000083200, ISSN: 0021-9258.

Hawiger J, Veach RA, Liu XY, Timmons S, Ballard DW. IkappaB kinase complex is an intracellular target for endotoxic lipopolysaccharide in human monocytic cells. Blood. 1999 Sep 9/1/1999; 94(5): 1711-6. PMID: 10477696, ISSN: 0006-4971.

Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 1995 Jun 6/16/1995; 270(24): 14255-8. PMID: 7782278, ISSN: 0021-9258.

Lin, Y.Z., Yao, S.Y., Veach, R.A., and Hawiger, J.. A novel method for delivering synthetic peptides into living cells to regulate intracellular signal transduction. Peptides: Chemistry, Structure, and Biology (Eds. Pravin T.P. Kaumaya and Hodges, R.S.) Mayflower Scientific Ltd. 1995; 160-2.

Read MA, Cordle SR, Veach RA, Carlisle CD, Hawiger J. Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 1993 Nov 11/1/1993; 90(21): 9887-91. PMID: 7694295, PMCID: PMC47677, ISSN: 0027-8424.

Rall GF, Kupershmidt S, Sugg N, Veach RA, Ben-Porat T. Functions of the sequences at the ends of the inverted repeats of pseudorabies virus. J. Virol. 1992 Mar; 66(3): 1506-19. PMID: 1310762, PMCID: PMC240876, ISSN: 0022-538X.

Rall GF, Lu ZQ, Sugg N, Veach RA, Ben-Porat T. Acquisition of an additional internal cleavage site differentially affects the ability of pseudorabies virus to multiply in different host cells. J. Virol. 1991 Dec; 65(12): 6604-11. PMID: 1658364, PMCID: PMC250723, ISSN: 0022-538X.

Ben-Porat T, DeMarchi J, Pendrys J, Veach RA, Kaplan AS. Proteins specified by the short unique region of the genome of pseudorabies virus play a role in the release of virions from certain cells. J. Virol. 1986 Jan; 57(1): 191-6. PMID: 3001344, PMCID: PMC252714, ISSN: 0022-538X.

Ben-Porat T, Veach RA, Blankenship ML, Kaplan AS. Differential association with cellular substructures of pseudorabies virus DNA during early and late phases of replication. Virology. 1984 Dec; 139(2): 205-22. PMID: 6097024, ISSN: 0042-6822.

Ben-Porat T, Deatly A, Veach RA, Blankenship ML. Equalization of the inverted repeat sequences of the pseudorabies virus genome by intermolecular recombination. Virology. 1984 Jan 1/30/1984; 132(2): 303-14. PMID: 6322414, ISSN: 0042-6822.

Ben-Porat T, Veach RA, Ihara S. Localization of the regions of homology between the genomes of herpes simplex virus, type 1, and pseudorabies virus. Virology. 1983 May; 127(1): 194-204. PMID: 6305015, ISSN: 0042-6822.

Ben-Porat T, Veach RA, Hampl H. Functions of the major nonstructural DNA binding protein of a herpesvirus (pseudorabies). Virology. 1983 Jan 1/30/1983; 124(2): 411-24. PMID: 6297164, ISSN: 0042-6822.

Ben-Porat T, Brown L, Veach RA. Recombination occurs mainly between parental genomes and precedes DNA replication in pseudorabies virus-infected cells. J. Virol. 1982 Oct; 44(1): 134-43. PMID: 6292481, PMCID: PMC256247, ISSN: 0022-538X.

Ben-Porat T, Veach RA, Ladin BF. Replication of herpesvirus DNA. VI. Virions containing either isomer of pseudorabies virus DNA are infectious. Virology. 1980 Apr 4/30/1980; 102(2): 370-80. PMID: 6245515, ISSN: 0042-6822.

Ben-Porat T, Veach RA. Origin of replication of the DNA of a herpesvirus (pseudorabies). Proc. Natl. Acad. Sci. U.S.A. 1980 Jan; 77(1): 172-5. PMID: 6244541, PMCID: PMC348230, ISSN: 0027-8424.

Ben-Porat, T., Ladin, N., and Veach, R.A.. Replication of herpesvirus DNA. Microbiology. 1980; 270-4.