Peter D. Donofrio, M.D.

Faculty Appointments
Professor of Neurology
M.D., Medicine, Ohio State University, Columbus, OhioB.S., University of Notre Dame, South Bend, Indiana
Office Address
Medical Center North, AA0204B
1161 21st Street South
Nashville, TN 37232
Research Keywords
Peripheral Neuropathy and in Motor Neuron Disorders
Cartwright MS, Moore PS, Donofrio PD, Iskandar SS, Stratta RJ. Acute sensory neuropathy associated with rabbit antithymocyte globulin. Am. J. Transplant. 2007 Feb; 7(2): 484-6. PMID: 17283492, ISSN: 1600-6135.

Hobson-Webb LD, Roach ES, Donofrio PD. Metronidazole: newly recognized cause of autonomic neuropathy. J. Child Neurol. 2006 May; 21(5): 429-31. PMID: 16901452, ISSN: 0883-0738.

Hobson-Webb LD, Donofrio PD. Inflammatory neuropathies: an update on evaluation and treatment. Curr Rheumatol Rep. 2005 Oct; 7(5): 348-55. PMID: 16174482, ISSN: 1523-3774.

Donofrio PD, Raskin P, Rosenthal NR, Hewitt DJ, Jordan DM, Xiang J, Vinik AI, . Safety and effectiveness of topiramate for the management of painful diabetic peripheral neuropathy in an open-label extension study. Clin Ther. 2005 Sep; 27(9): 1420-31. PMID: 16291415, PII: S0149-2918(05)00176-1, DOI: 10.1016/j.clinthera.2005.09.011, ISSN: 0149-2918.

Donofrio PD. Chronic inflammatory demyelinating polyradiculoneuropathy: new views and guidelines [editorial]. J. Peripher. Nerv. Syst. 2005 Sep; 10(3): 217-9. PMID: 16221282, PII: JNS10301, DOI: 10.1111/j.1085-9489.2005.10301.x, ISSN: 1085-9489.

Cartwright MS, Donofrio PD, Ybema KD, Walker FO. Detection of a brachial artery pseudoaneurysm using ultrasonography and EMG. Neurology. 2005 Aug 8/23/2005; 65(4): 649. PMID: 16116140, PII: 65/4/649, DOI: 10.1212/, ISSN: 1526-632X.

Cartwright MS, Jeffery DR, Nuss GR, Donofrio PD. Statin-associated exacerbation of myasthenia gravis. Neurology. 2004 Dec 12/14/2004; 63(11): 2188. PMID: 15596782, PII: 63/11/2188, ISSN: 1526-632X.

Raskin P, Donofrio PD, Rosenthal NR, Hewitt DJ, Jordan DM, Xiang J, Vinik AI, . Topiramate vs placebo in painful diabetic neuropathy: analgesic and metabolic effects. Neurology. 2004 Sep 9/14/2004; 63(5): 865-73. PMID: 15365138, PII: 63/5/865, ISSN: 1526-632X.

Jordan JR, Paruthi S, Pichardo RO, Challa VR, Donofrio PD, Jorizzo JL. Spontaneously remitting dermatomyositis. J Eur Acad Dermatol Venereol. 2004 Jul; 18(4): 495-8. PMID: 15196172, PII: JDV962, DOI: 10.1111/j.1468-3083.2004.00962.x, ISSN: 0926-9959.

Donofrio PD. Immunotherapy of idiopathic inflammatory neuropathies. Muscle Nerve. 2003 Sep; 28(3): 273-92. PMID: 12929187, DOI: 10.1002/mus.10402, ISSN: 0148-639X.

Cudkowicz ME, Shefner JM, Schoenfeld DA, Brown RH, Johnson H, Qureshi M, Jacobs M, Rothstein JD, Appel SH, Pascuzzi RM, Heiman-Patterson TD, Donofrio PD, David WS, Russell JA, Tandan R, Pioro EP, Felice KJ, Rosenfeld J, Mandler RN, Sachs GM, Bradley WG, Raynor EM, Baquis GD, Belsh JM, Novella S, Goldstein J, Hulihan J, . A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis. Neurology. 2003 Aug 8/26/2003; 61(4): 456-64. PMID: 12939417, ISSN: 1526-632X.

Caress JB, Cartwright MS, Donofrio PD, Peacock JE. The clinical features of 16 cases of stroke associated with administration of IVIg. Neurology. 2003 Jun 6/10/2003; 60(11): 1822-4. PMID: 12796539, ISSN: 1526-632X.

Donofrio PD, Busis NA. Regulatory and reimbursement issues in treating patients with immune-mediated neuropathies. Neurology. 2002 Dec 12/24/2002; 59(12 Suppl 6): S41-5. PMID: 12499470, ISSN: 0028-3878.

Mendell JR, Barohn RJ, Freimer ML, Kissel JT, King W, Nagaraja HN, Rice R, Campbell WW, Donofrio PD, Jackson CE, Lewis RA, Shy M, Simpson DM, Parry GJ, Rivner MH, Thornton CA, Bromberg MB, Tandan R, Harati Y, Giuliani MJ, . Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. Neurology. 2001 Feb 2/27/2001; 56(4): 445-9. PMID: 11222785, ISSN: 0028-3878.

Donofrio PD. Electrophysiologic evaluations. Neurol Clin. 2000 Aug; 18(3): 601-13. PMID: 10873233, ISSN: 0733-8619.

Donofrio PD, Bird SJ, Assimos DG, Mathes DD. Iatrogenic superior gluteal mononeuropathy. Muscle Nerve. 1998 Dec; 21(12): 1794-6. PMID: 9843087, PII: 10.1002/(SICI)1097-4598(199812)21:12<1794::AID-MUS27>3.0.CO;2-B, ISSN: 0148-639X.

Mathes DD, Assimos DG, Donofrio PD. Rhabdomyolysis and myonecrosis in a patient in the lateral decubitus position. Anesthesiology. 1996 Mar; 84(3): 727-9. PMID: 8659803, ISSN: 0003-3022.

Chen MY, Donofrio PD, Frederick MG, Ott DJ, Pikna LA. Videofluoroscopic evaluation of patients with Guillain-Barré syndrome. Dysphagia. 1996; 11(1): 11-3. PMID: 8556871, ISSN: 0179-051X.

Donofrio PD. AAEM case report #28: monomelic amyotrophy. Muscle Nerve. 1994 Oct; 17(10): 1129-34. PMID: 7935519, DOI: 10.1002/mus.880171002, ISSN: 0148-639X.

Butterworth J, Donofrio PD, Hansen LB. Transient median nerve palsy after general anesthesia: does res ipsa loquitur apply?. Anesth. Analg. 1994 Jan; 78(1): 163-4. PMID: 8267154, ISSN: 0003-2999.

Donofrio PD, Stanton C, Miller VS, Oestreich L, Lefkowitz DS, Walker FO, Ely EW. Demyelinating polyneuropathy in eosinophilia-myalgia syndrome. Muscle Nerve. 1992 Jul; 15(7): 796-805. PMID: 1323757, DOI: 10.1002/mus.880150708, ISSN: 0148-639X.

Chen MY, Peele VN, Donati D, Ott DJ, Donofrio PD, Gelfand DW. Clinical and videofluoroscopic evaluation of swallowing in 41 patients with neurologic disease. Gastrointest Radiol. 1992; 17(2): 95-8. PMID: 1551517, ISSN: 0364-2356.

Thomas TD, Donofrio PD, Angelo J. Peripheral neuropathy in cold agglutinin disease. Muscle Nerve. 1991 Apr; 14(4): 331-4. PMID: 1851246, DOI: 10.1002/mus.880140407, ISSN: 0148-639X.

Sherman HB, Walker FO, Donofrio PD. Sensitivity for detecting fibrillation potentials: a comparison between concentric and monopolar needle electrodes. Muscle Nerve. 1990 Nov; 13(11): 1023-6. PMID: 2233858, DOI: 10.1002/mus.880131104, ISSN: 0148-639X.

Donofrio PD, Albers JW. AAEM minimonograph #34: polyneuropathy: classification by nerve conduction studies and electromyography. Muscle Nerve. 1990 Oct; 13(10): 889-903. PMID: 2172810, DOI: 10.1002/mus.880131002, ISSN: 0148-639X.

Dirr LY, Elster AD, Donofrio PD, Smith M. Evolution of brain MRI abnormalities in limbic encephalitis. Neurology. 1990 Aug; 40(8): 1304-6. PMID: 2166250, ISSN: 0028-3878.

Moeser P, Donofrio PD, Karstaedt N, Bechtold R, Greiss FC. MRI findings of sciatic endometriosis. Clin Imaging. 1990 Mar; 14(1): 64-6. PMID: 2322887, ISSN: 0899-7071.

Bromberg MB, Donofrio PD, Segal BM. Steroid-responsive electromyographic abnormalities in polymyalgia rheumatica. Muscle Nerve. 1990 Feb; 13(2): 138-41. PMID: 2314416, DOI: 10.1002/mus.880130209, ISSN: 0148-639X.

Walker FO, Donofrio PD, Harpold GJ, Ferrell WG. Sonographic imaging of muscle contraction and fasciculations: a correlation with electromyography. Muscle Nerve. 1990 Jan; 13(1): 33-9. PMID: 2183044, DOI: 10.1002/mus.880130108, ISSN: 0148-639X.

McGonagle TK, Levine SR, Donofrio PD, Albers JW. Spectrum of patients with EMG features of polyradiculopathy without neuropathy. Muscle Nerve. 1990 Jan; 13(1): 63-9. PMID: 2157981, DOI: 10.1002/mus.880130112, ISSN: 0148-639X.

Dirr LY, Donofrio PD, Patton JF, Troost BT. A false-positive edrophonium test in a patient with a brainstem glioma. Neurology. 1989 Jun; 39(6): 865-7. PMID: 2725888, ISSN: 0028-3878.

Donofrio PD, Challa VR, Hackshaw BT, Mills SA, Cordell AR. Cardiac transplantation in a patient with muscular dystrophy and cardiomyopathy. Arch. Neurol. 1989 Jun; 46(6): 705-7. PMID: 2658928, ISSN: 0003-9942.

Donofrio PD, Alessi AG, Albers JW, Knapp RH, Blaivas M. Electrodiagnostic evolution of carcinomatous sensory neuronopathy. Muscle Nerve. 1989 Jun; 12(6): 508-13. PMID: 2542789, DOI: 10.1002/mus.880120612, ISSN: 0148-639X.

Castelbaum AR, Donofrio PD, Walker FO, Troost BT. Laxative abuse causing hypermagnesemia, quadriparesis, and neuromuscular junction defect. Neurology. 1989 May; 39(5): 746-7. PMID: 2710370, ISSN: 0028-3878.

Donofrio PD, Kelly JJ. AAEE case report #17: Peripheral neuropathy in monoclonal gammopathy of undetermined significance. Muscle Nerve. 1989 Jan; 12(1): 1-8. PMID: 2546074, DOI: 10.1002/mus.880120102, ISSN: 0148-639X.

Albers JW, Kallenbach LR, Fine LJ, Langolf GD, Wolfe RA, Donofrio PD, Alessi AG, Stolp-Smith KA, Bromberg MB. Neurological abnormalities associated with remote occupational elemental mercury exposure. Ann. Neurol. 1988 Nov; 24(5): 651-9. PMID: 2849369, DOI: 10.1002/ana.410240510, ISSN: 0364-5134.

Donofrio PD, Walker FO. Tabes dorsalis: electrodiagnostic features. J. Neurol. Neurosurg. Psychiatr. 1988 Aug; 51(8): 1097-9. PMID: 3216214, PMCID: PMC1033124, ISSN: 0022-3050.

Latov N, Hays AP, Donofrio PD, Liao J, Ito H, McGinnis S, Konstadoulakis M, Freddo L, Shy ME. Monoclonal IgM with unique specificity to gangliosides GM1 and GD1b and to lacto-N-tetraose associated with human motor neuron disease. Neurology. 1988 May; 38(5): 763-8. PMID: 2452383, ISSN: 0028-3878.

Donofrio PD, Wilbourn AJ, Albers JW, Rogers L, Salanga V, Greenberg HS. Acute arsenic intoxication presenting as Guillain-Barré-like syndrome. Muscle Nerve. 1987 Feb; 10(2): 114-20. PMID: 3029587, DOI: 10.1002/mus.880100203, ISSN: 0148-639X.

Berent S, Sackellares JC, Giordani B, Wagner JG, Donofrio PD, Abou-Khalil B. Zonisamide (CI-912) and cognition: results from preliminary study. Epilepsia. 1987 Jan; 28(1): 61-7. PMID: 3098556, ISSN: 0013-9580.

Beauchamp ML, Kemink JL, Donofrio PD. Myasthenia gravis: onset following neurotologic surgery. Am J Otol. 1986 Jul; 7(4): 302-4. PMID: 3740240, ISSN: 0192-9763.

Freddo L, Yu RK, Latov N, Donofrio PD, Hays AP, Greenberg HS, Albers JW, Allessi AG, Keren D. Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patient with motor neuron disease. Neurology. 1986 Apr; 36(4): 454-8. PMID: 3960319, ISSN: 0028-3878.

Donofrio PD, Sackellares C, Madsen JA, Matsuo F, Abou-Khalil B, Berent S, Wagner J, Ater SB, Mavor H, Gay PE. Pilot study of fluzinamide (N-methyl-3-[3-(trifluoromethyl)phenoxy]-1-azetidinecarboxamide) in refractory partial seizures. Neurology. 1985 Aug; 35(8): 1239-41. PMID: 4022365, ISSN: 0028-3878.

Albers JW, Donofrio PD, McGonagle TK. Sequential electrodiagnostic abnormalities in acute inflammatory demyelinating polyradiculoneuropathy. Muscle Nerve. 1985 Jul; 8(6): 528-39. PMID: 16758578, ISSN: 0148-639X.

Donofrio PD, Tandan R, Albers JW. Plasma exchange in chronic inflammatory demyelinating polyradiculoneuropathy. Muscle Nerve. 1985 May; 8(4): 321-7. PMID: 16758599, ISSN: 0148-639X.

Sackellares JC, Donofrio PD, Wagner JG, Abou-Khalil B, Berent S, Aasved-Hoyt K. Pilot study of zonisamide (1,2-benzisoxazole-3-methanesulfonamide) in patients with refractory partial seizures. Epilepsia. 1985 May; 26(3): 206-11. PMID: 3924586, ISSN: 0013-9580.

Donofrio PD, Albers JW, Greenberg HS, Mitchell BS. Peripheral neuropathy in osteosclerotic myeloma: clinical and electrodiagnostic improvement with chemotherapy. Muscle Nerve. 1984 Feb; 7(2): 137-41. PMID: 6325905, DOI: 10.1002/mus.880070209, ISSN: 0148-639X.

Wagner JG, Sackellares JC, Donofrio PD, Berent S, Sakmar E. Nonlinear pharmacokinetics of CI-912 in adult epileptic patients. Ther Drug Monit. 1984; 6(3): 277-83. PMID: 6506134, ISSN: 0163-4356.