Robert N. Piana, M.D.

Faculty Appointments
Professor of Medicine
M.D., MEDICINE, University of Pennsylvania, Philadelphia, PennsylvaniaA.B., Harvard University, Cambridge, Massachusetts
Office Address
1215 21st Ave
5th Fl MCE Ste. 5209
TN 8802
Halliday SJ, Hemnes AR, Robbins IM, Pugh ME, Zhao DX, Piana RN, Fong PP, Brittain EL. Prognostic value of acute vasodilator response in pulmonary arterial hypertension: beyond the "classic" responders. J. Heart Lung Transplant [print-electronic]. 2015 Mar; 34(3): 312-8. PMID: 25577565, PMCID: PMC4380573, PII: S1053-2498(14)01424-7, DOI: 10.1016/j.healun.2014.10.003, ISSN: 1557-3117.

Hess CN, Peterson ED, Neely ML, Dai D, Hillegass WB, Krucoff MW, Kutcher MA, Messenger JC, Pancholy S, Piana RN, Rao SV. Response to letter regarding article, "The learning curve for transradial percutaneous coronary intervention among operators in the United States: a study from the National Cardiovascular Data Registry" [letter]. Circulation. 2015 Feb 2/24/2015; 131(8): e358. PMID: 25712065, PII: CIRCULATIONAHA.114.013278, DOI: 10.1161/CIRCULATIONAHA.114.013278, ISSN: 1524-4539.

Young MN, Hollenbeck RD, Pollock JS, McPherson JA, Fredi JL, Piana RN, Mah ML, Fish FA, Markham L. Effectiveness of mild therapeutic hypothermia following cardiac arrest in adult patients with congenital heart disease. Am. J. Cardiol [print-electronic]. 2014 Jul 7/1/2014; 114(1): 128-30. PMID: 24819894, PII: S0002-9149(14)00969-2, DOI: 10.1016/j.amjcard.2014.04.012, ISSN: 1879-1913.

Hess CN, Peterson ED, Neely ML, Dai D, Hillegass WB, Krucoff MW, Kutcher MA, Messenger JC, Pancholy S, Piana RN, Rao SV. The learning curve for transradial percutaneous coronary intervention among operators in the United States: a study from the National Cardiovascular Data Registry. Circulation [print-electronic]. 2014 Jun 6/3/2014; 129(22): 2277-86. PMID: 24756064, PMCID: PMC4048735, PII: CIRCULATIONAHA.113.006356, DOI: 10.1161/CIRCULATIONAHA.113.006356, ISSN: 1524-4539.

Hess CN, Rao SV, Dai D, Neely ML, Piana RN, Messenger JC, Peterson ED. Predicting target vessel revascularization in older patients undergoing percutaneous coronary intervention in the drug-eluting stent era. Am. Heart J [print-electronic]. 2014 Apr; 167(4): 576-584.e2. PMID: 24655708, PMCID: PMC4157635, PII: S0002-8703(14)00010-6, DOI: 10.1016/j.ahj.2013.12.017, ISSN: 1097-6744.

Robbins IM, Hemnes AR, Pugh ME, Brittain EL, Zhao DX, Piana RN, Fong PP, Newman JH. High prevalence of occult pulmonary venous hypertension revealed by fluid challenge in pulmonary hypertension. Circ Heart Fail [print-electronic]. 2014 Jan; 7(1): 116-22. PMID: 24297689, PMCID: PMC3934572, PII: CIRCHEARTFAILURE.113.000468, DOI: 10.1161/CIRCHEARTFAILURE.113.000468, ISSN: 1941-3297.

Piana RN, Kirshner HS. Closure of the patent foramen ovale: because we can, should we? And in whom? [editorial]. JACC Cardiovasc Interv. 2013 Nov; 6(11): 1184-5. PMID: 24262619, PII: S1936-8798(13)01384-8, DOI: 10.1016/j.jcin.2013.10.001, ISSN: 1876-7605.

Robbins IM, Newman JH, Johnson RF, Hemnes AR, Fremont RD, Piana RN, Zhao DX, Byrne DW. Association of the metabolic syndrome with pulmonary venous hypertension. Chest [print-electronic]. 2009 Jul; 136(1): 31-6. PMID: 19188551, PMCID: PMC2716716, PII: S0012-3692(09)60403-7, DOI: 10.1378/chest.08-2008, ISSN: 1931-3543.

Zhao DX, Leacche M, Balaguer JM, Boudoulas KD, Damp JA, Greelish JP, Byrne JG, , Ahmad RM, Ball SK, Cleator JH, Deegan RJ, Eagle SS, Fong PP, Fredi JL, Hoff SJ, Jennings HS, McPherson JA, Piana RN, Pretorius M, Robbins MA, Slosky DA, Thompson A. Routine intraoperative completion angiography after coronary artery bypass grafting and 1-stop hybrid revascularization results from a fully integrated hybrid catheterization laboratory/operating room. J. Am. Coll. Cardiol. 2009 Jan 1/20/2009; 53(3): 232-41. PMID: 19147039, PII: S0735-1097(08)03463-3, DOI: 10.1016/j.jacc.2008.10.011, ISSN: 1558-3597.

Muldowney JA, Stringham JR, Levy SE, Gleaves LA, Eren M, Piana RN, Vaughan DE. Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2007 Feb; 27(2): 400-6. PMID: 17158352, PII: 01.ATV.0000254677.12861.b8, DOI: 10.1161/01.ATV.0000254677.12861.b8, ISSN: 1524-4636.

Kumar S, Piana RN, Byrne JG. Image-guided surgical ligation of the supreme branch of left internal mammary artery: a case report. Innovations (Phila). 2006; 1(5): 279-80. PMID: 22436761, PII: 01243895-200600150-00014, DOI: 10.1097/01.IMI.0000229133.95803.6e, ISSN: 1556-9845.

Epstein AM, Weissman JS, Schneider EC, Gatsonis C, Leape LL, Piana RN. Race and gender disparities in rates of cardiac revascularization: do they reflect appropriate use of procedures or problems in quality of care?. Med Care. 2003 Nov; 41(11): 1240-55. PMID: 14583687, DOI: 10.1097/01.MLR.0000093423.38746.8C, ISSN: 0025-7079.

Resnic FS, Wainstein M, Lee MK, Behrendt D, Wainstein RV, Ohno-Machado L, Kirshenbaum JM, Rogers CD, Popma JJ, Piana R. No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention. Am. Heart J. 2003 Jan; 145(1): 42-6. PMID: 12514653, PII: S0002870302947459, DOI: 10.1067/mhj.2003.36, ISSN: 1097-6744.

Leape LL, Weissman JS, Schneider EC, Piana RN, Gatsonis C, Epstein AM. Adherence to practice guidelines: the role of specialty society guidelines. Am. Heart J. 2003 Jan; 145(1): 19-26. PMID: 12514650, PII: S0002870302947447, DOI: 10.1067/mhj.2003.35, ISSN: 1097-6744.

Piana RN, Adams MR, Orford JL, Popma JJ, Adams DH, Goldhaber SZ. Rescue percutaneous coronary intervention immediately following coronary artery bypass grafting. Chest. 2001 Oct; 120(4): 1417-20. PMID: 11591594, ISSN: 0012-3692.

Simon DI, Liu CB, Ganz P, Kirshenbaum JM, Piana RN, Rogers C, Selwyn AP, Popma JJ. A comparative study of light transmission aggregometry and automated bedside platelet function assays in patients undergoing percutaneous coronary intervention and receiving abciximab, eptifibatide, or tirofiban. Catheter Cardiovasc Interv. 2001 Apr; 52(4): 425-32. PMID: 11285593, DOI: 10.1002/ccd.1096, ISSN: 1522-1946.

Fang JC, Kinlay S, Hikita H, Suh JH, Piana RN, Selwyn AP, Frei B, Morrow JD, Ganz P. Relation of preservation of nitric oxide-dependent coronary vasomotor function to plasma vitamin C concentrations in cardiac transplant recipients. Am. J. Cardiol. 2000 Aug 8/15/2000; 86(4): 460-2. PMID: 10946045, PII: S0002-9149(00)00967-X, ISSN: 0002-9149.

Giugliano RP, McCabe CH, Sequeira RF, Frey MJ, Henry TD, Piana RN, Tamby JF, Jensen BK, Nicolas SB, Jennings LK, Wise RJ, Braunwald E. First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: results of the TIMI 15A and 15B trials. Am. Heart J. 2000 Jul; 140(1): 81-93. PMID: 10874267, PII: S0002870300911864, ISSN: 0002-8703.

Shah PB, Popma JJ, Piana RN. Bivalirudin in Percutaneous Coronary Interventions and Acute Coronary Syndromes: New Concepts, New Directions. Curr Interv Cardiol Rep. 1999 Dec; 1(4): 346-58. PMID: 11096641, ISSN: 1523-3839.

de Lemos JA, Delacretaz E, Piana RN, Smith T, Rivero J, Simon DI, Friedman PL. Images in cardiovascular medicine. Ebstein's anomaly associated with an anomalous coronary artery, 2 myocardial bridges, and a mahaim fiber. Circulation. 1999 Oct 10/19/1999; 100(16): 1757-9. PMID: 10525497, ISSN: 1524-4539.

Popma JJ, Piana RN, Prpic R. Clinical trials in interventional cardiology. Curr. Opin. Cardiol. 1999 Sep; 14(5): 412-8. PMID: 10500903, ISSN: 0268-4705.

Popma JJ, Prpic R, Lansky AJ, Piana R. Heparin dosing in patients undergoing coronary intervention. Am. J. Cardiol. 1998 Oct 10/22/1998; 82(8B): 19P-24P. PMID: 9809888, ISSN: 0002-9149.

Gibson CM, Goel M, Cohen DJ, Piana RN, Deckelbaum LI, Harris KE, King SB. Six-month angiographic and clinical follow-up of patients prospectively randomized to receive either tirofiban or placebo during angioplasty in the RESTORE trial. Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis. J. Am. Coll. Cardiol. 1998 Jul; 32(1): 28-34. PMID: 9669245, PII: S0735109798001922, ISSN: 0735-1097.

Weinfeld MS, Kartashov A, Piana R, Hauptman PJ. Bradycardia: a late complication following cardiac transplantation. Am. J. Cardiol. 1996 Oct 10/15/1996; 78(8): 969-71. PMID: 8888681, PII: S0002-9149(96)00482-1, ISSN: 0002-9149.

Piana RN, Wang SY, Friedman M, Sellke FW. Angiotensin-converting enzyme inhibition preserves endothelium-dependent coronary microvascular responses during short-term ischemia-reperfusion. Circulation. 1996 Feb 2/1/1996; 93(3): 544-51. PMID: 8565174, ISSN: 0009-7322.

Piana RN, Bittl JA. Unstable angina: the role of percutaneous coronary angioplasty. Coron. Artery Dis. 1995 Oct; 6(10): 774-9. PMID: 8789669, ISSN: 0954-6928.

Gibson CM, Cannon CP, Piana RN, Breall JA, Sharaf B, Flatley M, Alexander B, Diver DJ, McCabe CH, Flaker GC. Angiographic predictors of reocclusion after thrombolysis: results from the Thrombolysis in Myocardial Infarction (TIMI) 4 trial. J. Am. Coll. Cardiol. 1995 Mar 3/1/1995; 25(3): 582-9. PMID: 7860900, PII: 073510979400423N, ISSN: 0735-1097.

Piana RN, Banitt PF, Nunez BN, Dai HB, Sellke FW. Coronary microvascular responses after exposure to iodinated contrast media. Invest Radiol. 1994 Oct; 29(10): 877-81. PMID: 7852038, ISSN: 0020-9996.

Sellke FW, Friedman M, Wang SY, Piana RN, Dai HB, Johnson RG. Adenosine and AICA-riboside fail to enhance microvascular endothelial preservation. Ann. Thorac. Surg. 1994 Jul; 58(1): 200-6. PMID: 8037525, ISSN: 0003-4975.

Moscucci M, Piana RN, Kuntz RE, Kugelmass AD, Carrozza JP, Senerchia C, Baim DS. Effect of prior coronary restenosis on the risk of subsequent restenosis after stent placement or directional atherectomy. Am. J. Cardiol. 1994 Jun 6/15/1994; 73(16): 1147-53. PMID: 8203330, ISSN: 0002-9149.

Piana RN, Moscucci M, Cohen DJ, Kugelmass AD, Senerchia C, Kuntz RE, Baim DS, Carrozza JP. Palmaz-Schatz stenting for treatment of focal vein graft stenosis: immediate results and long-term outcome. J. Am. Coll. Cardiol. 1994 May; 23(6): 1296-304. PMID: 8176086, PII: 0735-1097(94)90370-0, ISSN: 0735-1097.

Piana RN, Shafique T, Dai HB, Sellke FW. Epicardial and endocardial coronary microvascular responses: effects of ischemia-reperfusion. J. Cardiovasc. Pharmacol. 1994 Apr; 23(4): 539-46. PMID: 7516002, ISSN: 0160-2446.

Cohen DJ, Kuntz RE, Gordon SP, Piana RN, Safian RD, McKay RG, Baim DS, Grossman W, Diver DJ. Predictors of long-term outcome after percutaneous balloon mitral valvuloplasty. N. Engl. J. Med. 1992 Nov 11/5/1992; 327(19): 1329-35. PMID: 1406834, DOI: 10.1056/NEJM199211053271901, ISSN: 0028-4793.

Kuntz RE, Piana R, Pomerantz RM, Carrozza J, Fishman R, Mansour M, Safian RD, Baim DS. Changing incidence and management of abrupt closure following coronary intervention in the new device era. Cathet Cardiovasc Diagn. 1992 Nov; 27(3): 183-90. PMID: 1423573, ISSN: 0098-6569.

Kugelmass AD, Manning WJ, Piana RN, Weintraub RM, Baim DS, Grossman W. Coronary arteriovenous fistula presenting as congestive heart failure. Cathet Cardiovasc Diagn. 1992 May; 26(1): 19-25. PMID: 1499058, ISSN: 0098-6569.

Kuntz RE, Piana R, Schnitt SJ, Johnson RG, Safian RD, Baim DS. Early ostial vein graft stenosis: management by atherectomy. Cathet Cardiovasc Diagn. 1991 Sep; 24(1): 41-4. PMID: 1913791, ISSN: 0098-6569.

Landon MB, Gabbe SG, Piana R, Mennuti MT, Main EK. Neonatal morbidity in pregnancy complicated by diabetes mellitus: predictive value of maternal glycemic profiles. Am. J. Obstet. Gynecol. 1987 May; 156(5): 1089-95. PMID: 3578417, PII: 0002-9378(87)90116-5, ISSN: 0002-9378.