Talat Alp Ikizler, M.D.



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Faculty Appointments
Professor of Medicine Catherine McLaughlin Hakim Chair in Vascular Biology
M.D., Medicine, Istanbul Universitesi, Istanbul, Turkey
Office Address
S-3223 MCN
TN 2372
Research Description
Clinical Research Keywords
Nephrology, Nutrition, Metabolism, Acute Renal Failure, Hemodialysis, Vascular Access
Malhotra R, Lipworth L, Cavanaugh KL, Young BA, Tucker KL, Carithers TC, Taylor HA, Correa A, Kabagambe EK, Ikizler TA. Protein Intake and Long-term Change in Glomerular Filtration Rate in the Jackson Heart Study. J Ren Nutr [print-electronic]. 2018 Jul; 28(4): 245-50. PMID: 29452887, PII: S1051-2276(17)30284-4, DOI: 10.1053/j.jrn.2017.11.008, ISSN: 1532-8503.

Deger SM, Hewlett JR, Gamboa J, Ellis CD, Hung AM, Siew ED, Mamnungu C, Sha F, Bian A, Stewart TG, Abumrad NN, Ikizler TA. Insulin Resistance is a Significant Determinant of Sarcopenia in Advanced Kidney Disease. Am. J. Physiol. Endocrinol. Metab [print-electronic]. 2018 Jun 6/12/2018; PMID: 29894202, DOI: 10.1152/ajpendo.00070.2018, ISSN: 1522-1555.

Kaseda R, Tsuchida Y, Gamboa JL, Zhong J, Zhang L, Yang H, Dikalova A, Bian A, Davies S, Fogo AF, Linton MF, Brown NJ, Ikizler TA, Kon V. Angiotensin receptor blocker vs ACE inhibitor effects on HDL functionality in patients on maintenance hemodialysis. Nutr Metab Cardiovasc Dis [print-electronic]. 2018 Jun; 28(6): 582-91. PMID: 29691148, PMCID: PMC5959764, PII: S0939-4753(18)30090-5, DOI: 10.1016/j.numecd.2018.02.020, ISSN: 1590-3729.

Wyatt CM, Ikizler TA. Isotonic fluids for volume resuscitation: is it really 6 liters of one, half a dozen of another?. Kidney Int. 2018 Jun; 93(6): 1262-4. PMID: 29792267, PII: S0085-2538(18)30279-5, DOI: 10.1016/j.kint.2018.04.003, ISSN: 1523-1755.

Abdel-Kader K, Girard TD, Brummel NE, Saunders CT, Blume JD, Clark AJ, Vincz AJ, Ely EW, Jackson JC, Bell SP, Archer KR, Ikizler TA, Pandharipande PP, Siew ED. Acute Kidney Injury and Subsequent Frailty Status in Survivors of Critical Illness: A Secondary Analysis. Crit. Care Med. 2018 May; 46(5): e380-e388. PMID: 29373362, PMCID: PMC5899022, DOI: 10.1097/CCM.0000000000003003, ISSN: 1530-0293.

Ikizler TA. Safety of Low-Protein Diets and Ketoanalogue Supplementation in CKD [editorial]. Kidney Int Rep. 2018 May; 3(3): 510-2. PMID: 29854957, PMCID: PMC5976811, PII: S2468-0249(18)30035-4, DOI: 10.1016/j.ekir.2018.02.004, ISSN: 2468-0249.

Hung AM, Siew ED, Wilson OD, Perkins AM, Greevy RA, Horner J, Abdel-Kader K, Parr SK, Roumie CL, Griffin MR, Ikizler TA, Speroff T, Matheny ME. Risk of Hypoglycemia Following Hospital Discharge in Patients With Diabetes and Acute Kidney Injury. Diabetes Care [print-electronic]. 2018 Mar; 41(3): 503-12. PMID: 29326106, PMCID: PMC5829959, PII: dc17-1237, DOI: 10.2337/dc17-1237, ISSN: 1935-5548.

Parr SK, Matheny ME, Abdel-Kader K, Greevy RA, Bian A, Fly J, Chen G, Speroff T, Hung AM, Ikizler TA, Siew ED. Acute kidney injury is a risk factor for subsequent proteinuria. Kidney Int [print-electronic]. 2018 Feb; 93(2): 460-9. PMID: 28927644, PMCID: PMC5796522, PII: S0085-2538(17)30537-9, DOI: 10.1016/j.kint.2017.07.007, ISSN: 1523-1755.

Bansal N, Matheny ME, Greevy RA, Eden SK, Perkins AM, Parr SK, Fly J, Abdel-Kader K, Himmelfarb J, Hung AM, Speroff T, Ikizler TA, Siew ED. Acute Kidney Injury and Risk of Incident Heart Failure Among US Veterans. Am. J. Kidney Dis [print-electronic]. 2018 Feb; 71(2): 236-45. PMID: 29162339, PII: S0272-6386(17)30977-0, DOI: 10.1053/j.ajkd.2017.08.027, ISSN: 1523-6838.

Pandey AK, Singhi EK, Arroyo JP, Ikizler TA, Gould ER, Brown J, Beckman JA, Harrison DG, Moslehi J. Mechanisms of VEGF (Vascular Endothelial Growth Factor) Inhibitor-Associated Hypertension and Vascular Disease. Hypertension [print-electronic]. 2018 Feb; 71(2): e1-e8. PMID: 29279311, PMCID: PMC5825002, PII: HYPERTENSIONAHA.117.10271, DOI: 10.1161/HYPERTENSIONAHA.117.10271, ISSN: 1524-4563.

Kaseda R, Tsuchida Y, Yang HC, Yancey PG, Zhong J, Tao H, Bian A, Fogo AB, Linton MRF, Fazio S, Ikizler TA, Kon V. Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism. BMC Nephrol. 2018 Jan 1/27/2018; 19(1): 17. PMID: 29374468, PMCID: PMC5787279, PII: 10.1186/s12882-018-0814-8, DOI: 10.1186/s12882-018-0814-8, ISSN: 1471-2369.

Ikizler TA, Berns JS. Transformation of ABIM and What the Changes Mean to Nephrologists. Clin J Am Soc Nephrol [print-electronic]. 2018 Jan 1/6/2018; 13(1): 164-6. PMID: 29018102, PMCID: PMC5753312, PII: CJN.05700517, DOI: 10.2215/CJN.05700517, ISSN: 1555-905X.

Ikizler TA, Robinson-Cohen C, Ellis C, Headley SAE, Tuttle K, Wood RJ, Evans EE, Milch CM, Moody KA, Germain M, Limkunakul C, Bian A, Stewart TG, Himmelfarb J. Metabolic Effects of Diet and Exercise in Patients with Moderate to Severe CKD: A Randomized Clinical Trial. J. Am. Soc. Nephrol [print-electronic]. 2018 Jan; 29(1): 250-9. PMID: 29038285, PMCID: PMC5748901, PII: ASN.2017010020, DOI: 10.1681/ASN.2017010020, ISSN: 1533-3450.

Bachmann KN, Deger SM, Alsouqi A, Huang S, Xu M, Ferguson JF, Su YR, Niswender KD, Ikizler TA, Wang TJ. Acute effects of insulin on circulating natriuretic peptide levels in humans. PLoS ONE. 2018; 13(5): e0196869. PMID: 29758041, PMCID: PMC5951576, PII: PONE-D-17-42749, DOI: 10.1371/journal.pone.0196869, ISSN: 1932-6203.

Deger SM, Hung AM, Gamboa JL, Siew ED, Ellis CD, Booker C, Sha F, Li H, Bian A, Stewart TG, Zent R, Mitch WE, Abumrad NN, Ikizler TA. Systemic inflammation is associated with exaggerated skeletal muscle protein catabolism in maintenance hemodialysis patients. JCI Insight [print-electronic]. 2017 Nov 11/16/2017; 2(22): PMID: 29202452, PMCID: PMC5752392, PII: 95185, DOI: 10.1172/jci.insight.95185, ISSN: 2379-3708.

Salat H, Javier A, Siew ED, Figueroa R, Lipworth L, Kabagambe E, Bian A, Stewart TG, El-Sourady MH, Karlekar M, Cardona CY, Ikizler TA, Abdel-Kader K. Nephrology Provider Prognostic Perceptions and Care Delivered to Older Adults with Advanced Kidney Disease. Clin J Am Soc Nephrol [print-electronic]. 2017 Nov 11/7/2017; 12(11): 1762-70. PMID: 28923833, PMCID: PMC5672972, PII: CJN.03830417, DOI: 10.2215/CJN.03830417, ISSN: 1555-905X.

Wild MG, Wallston KA, Green JA, Beach LB, Umeukeje E, Wright Nunes JA, Ikizler TA, Steed J, Cavanaugh KL. The Perceived Medical Condition Self-Management Scale can be applied to patients with chronic kidney disease. Kidney Int [print-electronic]. 2017 Oct; 92(4): 972-8. PMID: 28528132, PMCID: PMC5610608, PII: S0085-2538(17)30213-2, DOI: 10.1016/j.kint.2017.03.018, ISSN: 1523-1755.

Javier AD, Figueroa R, Siew ED, Salat H, Morse J, Stewart TG, Malhotra R, Jhamb M, Schell JO, Cardona CY, Maxwell CA, Ikizler TA, Abdel-Kader K. Reliability and Utility of the Surprise Question in CKD Stages 4 to 5. Am. J. Kidney Dis [print-electronic]. 2017 Jul; 70(1): 93-101. PMID: 28215946, PMCID: PMC5771496, PII: S0272-6386(17)30006-9, DOI: 10.1053/j.ajkd.2016.11.025, ISSN: 1523-6838.

Deger SM, Wang P, Fissell R, Ellis CD, Booker C, Sha F, Morse JL, Stewart TG, Gore JC, Siew ED, Titze J, Ikizler TA. Tissue sodium accumulation and peripheral insulin sensitivity in maintenance hemodialysis patients. J Cachexia Sarcopenia Muscle [print-electronic]. 2017 Jun; 8(3): 500-7. PMID: 28150400, PMCID: PMC5476848, DOI: 10.1002/jcsm.12179, ISSN: 2190-6009.

Janak JC, Stewart IJ, Sosnov JA, Howard JT, Siew ED, Chan MM, Wickersham N, Ikizler TA, Chung KK. Urinary Biomarkers are Associated with Severity and Mechanism of Injury. Shock. 2017 May; 47(5): 593-8. PMID: 27798535, PMCID: PMC5392149, DOI: 10.1097/SHK.0000000000000784, ISSN: 1540-0514.

Rivara MB, Yeung CK, Robinson-Cohen C, Phillips BR, Ruzinski J, Rock D, Linke L, Shen DD, Ikizler TA, Himmelfarb J. Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial. Am. J. Kidney Dis [print-electronic]. 2017 Mar; 69(3): 389-99. PMID: 27927588, PMCID: PMC5616172, PII: S0272-6386(16)30573-X, DOI: 10.1053/j.ajkd.2016.08.041, ISSN: 1523-6838.

Malhotra R, Deger SM, Salat H, Bian A, Stewart TG, Booker C, Vincz A, Pouliot B, Ikizler TA. Sarcopenic Obesity Definitions by Body Composition and Mortality in the Hemodialysis Patients. J Ren Nutr [print-electronic]. 2017 Mar; 27(2): 84-90. PMID: 27876469, PMCID: PMC5318243, PII: S1051-2276(16)30143-1, DOI: 10.1053/j.jrn.2016.09.010, ISSN: 1532-8503.

Nowak KL, Chonchol M, Ikizler TA, Farmer-Bailey H, Salas N, Chaudhry R, Wang W, Smits G, Tengesdal I, Dinarello CA, Hung AM. IL-1 Inhibition and Vascular Function in CKD. J. Am. Soc. Nephrol [print-electronic]. 2017 Mar; 28(3): 971-80. PMID: 27647856, PMCID: PMC5328163, PII: ASN.2016040453, DOI: 10.1681/ASN.2016040453, ISSN: 1533-3450.

Pratt RD, Swinkels DW, Ikizler TA, Gupta A. Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers. J Clin Pharmacol [print-electronic]. 2017 Mar; 57(3): 312-20. PMID: 27557937, PMCID: PMC5324677, DOI: 10.1002/jcph.819, ISSN: 1552-4604.

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR, . A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury. Am. J. Respir. Crit. Care Med. 2017 Feb 2/15/2017; 195(4): 482-90. PMID: 27576016, PMCID: PMC5378420, DOI: 10.1164/rccm.201603-0518OC, ISSN: 1535-4970.

Wang P, Deger MS, Kang H, Ikizler TA, Titze J, Gore JC. Sex differences in sodium deposition in human muscle and skin. Magn Reson Imaging [print-electronic]. 2017 Feb; 36: 93-7. PMID: 27989912, PMCID: PMC5222810, PII: S0730-725X(16)30190-4, DOI: 10.1016/j.mri.2016.10.023, ISSN: 1873-5894.

Kensinger C, Hernandez A, Bian A, Fairchild M, Chen G, Lipworth L, Ikizler TA, Birdwell KA. Longitudinal assessment of cardiac morphology and function following kidney transplantation. Clin Transplant [print-electronic]. 2017 Jan; 31(1): PMID: 27801526, PMCID: PMC5215632, DOI: 10.1111/ctr.12864, ISSN: 1399-0012.

Hung AM, Roumie CL, Greevy RA, Grijalva CG, Liu X, Murff HJ, Ikizler TA, Griffin MR. Comparative Effectiveness of Second-Line Agents for the Treatment of Diabetes Type 2 in Preventing Kidney Function Decline. Clin J Am Soc Nephrol [print-electronic]. 2016 Dec 12/7/2016; 11(12): 2177-85. PMID: 27827311, PMCID: PMC5142060, PII: CJN.02630316, DOI: 10.2215/CJN.02630316, ISSN: 1555-905X.

Malhotra R, Cavanaugh KL, Blot WJ, Ikizler TA, Lipworth L, Kabagambe EK. Higher protein intake is associated with increased risk for incident end-stage renal disease among blacks with diabetes in the Southern Community Cohort Study. Nutr Metab Cardiovasc Dis [print-electronic]. 2016 Dec; 26(12): 1079-87. PMID: 27562875, PMCID: PMC5147554, PII: S0939-4753(16)30116-8, DOI: 10.1016/j.numecd.2016.07.009, ISSN: 1590-3729.

Lipworth L, Abdel-Kader K, Morse J, Stewart TG, Kabagambe EK, Parr SK, Birdwell KA, Matheny ME, Hung AM, Blot WJ, Ikizler TA, Siew ED. High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study. BMC Nephrol. 2016 Nov 11/24/2016; 17(1): 189. PMID: 27881100, PMCID: PMC5122006, PII: 10.1186/s12882-016-0411-7, DOI: 10.1186/s12882-016-0411-7, ISSN: 1471-2369.

Kensinger C, Bian A, Fairchild M, Chen G, Lipworth L, Ikizler TA, Birdwell KA. Long term evolution of endothelial function during kidney transplantation. BMC Nephrol. 2016 Oct 10/22/2016; 17(1): 160. PMID: 27770793, PMCID: PMC5075412, PII: 10.1186/s12882-016-0369-5, DOI: 10.1186/s12882-016-0369-5, ISSN: 1471-2369.

Malhotra R, Cavanaugh KL, Blot WJ, Ikizler TA, Lipworth L, Kabagambe EK. Dietary polyunsaturated fatty acids and incidence of end-stage renal disease in the Southern Community Cohort Study. BMC Nephrol. 2016 Oct 10/18/2016; 17(1): 152. PMID: 27756237, PMCID: PMC5070154, PII: 10.1186/s12882-016-0371-y, DOI: 10.1186/s12882-016-0371-y, ISSN: 1471-2369.

Sarkar S, Terry JG, Ikizler TA, Crouse JR, Carr JJ, Hung AM. The effect of high intensity statin use on liver density: A post hoc analysis of the coronary artery calcification treatment with zocor [CATZ] study [letter]. Obes Res Clin Pract [print-electronic]. 2016 Sep; 10(5): 613-5. PMID: 27670349, PII: S1871-403X(16)30082-5, DOI: 10.1016/j.orcp.2016.09.001, ISSN: 1871-403X.

Deger SM, Hung AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA. High Dose Omega-3 Fatty Acid Administration and Skeletal Muscle Protein Turnover in Maintenance Hemodialysis Patients. Clin J Am Soc Nephrol [print-electronic]. 2016 Jul 7/7/2016; 11(7): 1227-35. PMID: 27281699, PMCID: PMC4934832, PII: CJN.04150415, DOI: 10.2215/CJN.04150415, ISSN: 1555-905X.

Gamboa JL, Billings FT, Bojanowski MT, Gilliam LA, Yu C, Roshanravan B, Roberts LJ, Himmelfarb J, Ikizler TA, Brown NJ. Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. Physiol Rep. 2016 May; 4(9): PMID: 27162261, PMCID: PMC4873632, PII: 4/9/e12780, DOI: 10.14814/phy2.12780, ISSN: 2051-817X.

Siew ED, Parr SK, Abdel-Kader K, Eden SK, Peterson JF, Bansal N, Hung AM, Fly J, Speroff T, Ikizler TA, Matheny ME. Predictors of Recurrent AKI. J. Am. Soc. Nephrol [print-electronic]. 2016 Apr; 27(4): 1190-200. PMID: 26264853, PMCID: PMC4814177, PII: ASN.2014121218, DOI: 10.1681/ASN.2014121218, ISSN: 1533-3450.

Leaf DE, Christov M, Jüppner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Cai X, Wolf M, Waikar SS. Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery. Kidney Int [print-electronic]. 2016 Apr; 89(4): 939-48. PMID: 26924052, PMCID: PMC4801748, PII: S0085-2538(16)00224-6, DOI: 10.1016/j.kint.2015.12.035, ISSN: 1523-1755.

Morrell GR, Ikizler TA, Chen X, Heilbrun ME, Wei G, Boucher R, Beddhu S. Psoas Muscle Cross-sectional Area as a Measure of Whole-body Lean Muscle Mass in Maintenance Hemodialysis Patients. J Ren Nutr [print-electronic]. 2016 Mar 3/16/2016; PMID: 26994780, PII: S1051-2276(16)00041-8, DOI: 10.1053/j.jrn.2016.02.002, ISSN: 1532-8503.

de Boer IH, Zelnick L, Afkarian M, Ayers E, Curtin L, Himmelfarb J, Ikizler TA, Kahn SE, Kestenbaum B, Utzschneider K. Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD. J. Am. Soc. Nephrol [print-electronic]. 2016 Jan 1/28/2016; PMID: 26823551, PII: ASN.2015070756, DOI: 10.1681/ASN.2015070756, ISSN: 1533-3450.

Liu KD, Siew ED, Reeves WB, Himmelfarb J, Go AS, Hsu CY, Bennett MR, Devarajan P, Ikizler TA, Kaufman JS, Kimmel PL, Chinchilli VM, Parikh CR, . Storage Time and Urine Biomarker Levels in the ASSESS-AKI Study. PLoS ONE. 2016; 11(10): e0164832. PMID: 27788160, PMCID: PMC5082822, PII: PONE-D-16-05176, DOI: 10.1371/journal.pone.0164832, ISSN: 1932-6203.

Denny GB, Deger SM, Chen G, Bian A, Sha F, Booker C, Kesler JT, David S, Ellis CD, Ikizler TA. Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients. BMC Nutr [print-electronic]. 2016; 2: PMID: 27413537, PMCID: PMC4939826, DOI: 10.1186/s40795-016-0071-9, ISSN: 2055-0928.

Dong J, Li YJ, Xu R, Ikizler TA, Wang HY. Ketoacid Supplementation Partially Improves Metabolic Parameters in Patients on Peritoneal Dialysis. Perit Dial Int [print-electronic]. 2015 Dec; 35(7): 736-42. PMID: 26374833, PII: pdi.2014.00151, DOI: 10.3747/pdi.2014.00151, ISSN: 1718-4304.

Jhamb M, Cavanaugh KL, Bian A, Chen G, Ikizler TA, Unruh ML, Abdel-Kader K. Disparities in Electronic Health Record Patient Portal Use in Nephrology Clinics. Clin J Am Soc Nephrol [print-electronic]. 2015 Nov 11/6/2015; 10(11): 2013-22. PMID: 26493242, PMCID: PMC4633780, PII: CJN.01640215, DOI: 10.2215/CJN.01640215, ISSN: 1555-905X.

King-Morris KR, Deger SM, Hung AM, Egbert PA, Ellis CD, Graves A, Shintani A, Ikizler TA. MEASUREMENT AND CORRELATION OF INDICES OF INSULIN RESISTANCE IN PATIENTS ON PERITONEAL DIALYSIS. Perit Dial Int [print-electronic]. 2015 Nov 11/2/2015; PMID: 26526047, PMCID: PMC4853288, PII: pdi.2013.00296, DOI: 10.3747/pdi.2013.00296, ISSN: 1718-4304.

Gupta A, Lin V, Guss C, Pratt R, Ikizler TA, Besarab A. Ferric pyrophosphate citrate administered via dialysate reduces erythropoiesis-stimulating agent use and maintains hemoglobin in hemodialysis patients. Kidney Int [print-electronic]. 2015 Nov; 88(5): 1187-94. PMID: 26154926, PMCID: PMC4653585, PII: S0085-2538(15)60995-4, DOI: 10.1038/ki.2015.203, ISSN: 1523-1755.

Cronin RM, VanHouten JP, Siew ED, Eden SK, Fihn SD, Nielson CD, Peterson JF, Baker CR, Ikizler TA, Speroff T, Matheny ME. National Veterans Health Administration inpatient risk stratification models for hospital-acquired acute kidney injury. J Am Med Inform Assoc [print-electronic]. 2015 Sep; 22(5): 1054-71. PMID: 26104740, PII: ocv051, DOI: 10.1093/jamia/ocv051, ISSN: 1527-974X.

Umeukeje EM, Merighi JR, Browne T, Victoroff JN, Umanath K, Lewis JB, Ikizler TA, Wallston KA, Cavanaugh K. Self-Motivation Is Associated With Phosphorus Control in End-Stage Renal Disease. J Ren Nutr [print-electronic]. 2015 Sep; 25(5): 433-9. PMID: 25912398, PMCID: PMC4546917, PII: S1051-2276(15)00068-0, DOI: 10.1053/j.jrn.2015.03.001, ISSN: 1532-8503.

Birdee GS, Rothman RL, Sohl SJ, Wertenbaker D, Wheeler A, Bossart C, Balasire O, Ikizler TA. Feasibility and Safety of Intradialysis Yoga and Education in Maintenance Hemodialysis Patients. J Ren Nutr [print-electronic]. 2015 Sep; 25(5): 445-53. PMID: 25869658, PII: S1051-2276(15)00063-1, DOI: 10.1053/j.jrn.2015.02.004, ISSN: 1532-8503.

Cavanaugh KL, Osborn CY, Tentori F, Rothman RL, Ikizler TA, Wallston KA. Performance of a brief survey to assess health literacy in patients receiving hemodialysis. Clin Kidney J [print-electronic]. 2015 Aug; 8(4): 462-8. PMID: 26251719, PMCID: PMC4515892, PII: sfv037, DOI: 10.1093/ckj/sfv037, ISSN: 2048-8505.

Berns JS, Ikizler TA. Quality training, quality board examinations, quality nephrologists [editorial]. Am. J. Kidney Dis. 2015 Jul; 66(1): 7-8. PMID: 26111903, PII: S0272-6386(15)00746-5, DOI: 10.1053/j.ajkd.2015.05.002, ISSN: 1523-6838.

Marcus RL, LaStayo PC, Ikizler TA, Wei G, Giri A, Chen X, Morrell G, Painter P, Beddhu S. Low Physical Function in Maintenance Hemodialysis Patients Is Independent of Muscle Mass and Comorbidity. J Ren Nutr [print-electronic]. 2015 Jul; 25(4): 371-5. PMID: 25836339, PMCID: PMC4469499, PII: S1051-2276(15)00043-6, DOI: 10.1053/j.jrn.2015.01.020, ISSN: 1532-8503.

Sanders ML, Karnes JH, Denny JC, Roden DM, Ikizler TA, Birdwell KA. Clinical and Genetic Factors Associated with Cutaneous Squamous Cell Carcinoma in Kidney and Heart Transplant Recipients. Transplant Direct. 2015 May; 1(4): PMID: 26146661, PMCID: PMC4486315, ISSN: 2373-8731.

Heegard KD, Stewart IJ, Cap AP, Sosnov JA, Kwan HK, Glass KR, Morrow BD, Latack W, Henderson AT, Saenz KK, Siew ED, Ikizler TA, Chung KK. Early acute kidney injury in military casualties. J Trauma Acute Care Surg. 2015 May; 78(5): 988-93. PMID: 25909420, PII: 01586154-201505000-00014, DOI: 10.1097/TA.0000000000000607, ISSN: 2163-0763.

Stenvinkel P, Carrero JJ, von Walden F, Ikizler TA, Nader GA. Muscle wasting in end-stage renal disease promulgates premature death: established, emerging and potential novel treatment strategies. Nephrol. Dial. Transplant [print-electronic]. 2015 Apr 4/24/2015; PMID: 25910496, PII: gfv122, DOI: 10.1093/ndt/gfv122, ISSN: 1460-2385.

Ikizler TA, Lovett DH, Chertow GM, Mitch WE, Schiller B. Navigating toward research success in times of uncertainty: funding opportunities for early career investigators in nephrology. Am. J. Kidney Dis [print-electronic]. 2015 Mar; 65(3): 381-3. PMID: 25542413, PII: S0272-6386(14)01444-9, DOI: 10.1053/j.ajkd.2014.11.008, ISSN: 1523-6838.

Kistler BM, Fitschen PJ, Ikizler TA, Wilund KR. Rethinking the restriction on nutrition during hemodialysis treatment. J Ren Nutr [print-electronic]. 2015 Mar; 25(2): 81-7. PMID: 25443693, PII: S1051-2276(14)00160-5, DOI: 10.1053/j.jrn.2014.08.008, ISSN: 1532-8503.

Parr SK, Clark AJ, Bian A, Shintani AK, Wickersham NE, Ware LB, Ikizler TA, Siew ED. Urinary L-FABP predicts poor outcomes in critically ill patients with early acute kidney injury. Kidney Int [print-electronic]. 2015 Mar; 87(3): 640-8. PMID: 25229339, PMCID: PMC4344867, PII: S0085-2538(15)30159-9, DOI: 10.1038/ki.2014.301, ISSN: 1523-1755.

Hung AM, Booker C, Ellis CD, Siew ED, Graves AJ, Shintani A, Abumrad NN, Himmelfarb J, Ikizler TA. Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients. Nephrol. Dial. Transplant [print-electronic]. 2015 Feb; 30(2): 266-74. PMID: 25204316, PMCID: PMC4309191, PII: gfu283, DOI: 10.1093/ndt/gfu283, ISSN: 1460-2385.

Jia T, Risérus U, Xu H, Lindholm B, Ärnlöv J, Sjögren P, Cederholm T, Larsson TE, Ikizler TA, Carrero JJ. Kidney function, ß-cell function and glucose tolerance in older men. J. Clin. Endocrinol. Metab [print-electronic]. 2015 Feb; 100(2): 587-93. PMID: 25429626, PMCID: PMC4318901, DOI: 10.1210/jc.2014-3313, ISSN: 1945-7197.

Gamboa JL, Pretorius M, Sprinkel KC, Brown NJ, Ikizler TA. Angiotensin converting enzyme inhibition increases ADMA concentration in patients on maintenance hemodialysis--a randomized cross-over study. BMC Nephrol. 2015; 16: 167. PMID: 26494370, PMCID: PMC4618919, PII: 10.1186/s12882-015-0162-x, DOI: 10.1186/s12882-015-0162-x, ISSN: 1471-2369.

Birdwell KA, Jaffe G, Bian A, Wu P, Ikizler TA. Assessment of arterial stiffness using pulse wave velocity in tacrolimus users the first year post kidney transplantation: a prospective cohort study. BMC Nephrol. 2015; 16: 93. PMID: 26133166, PMCID: PMC4489361, PII: 10.1186/s12882-015-0092-7, DOI: 10.1186/s12882-015-0092-7, ISSN: 1471-2369.

Stewart IJ, Glass KR, Howard JT, Morrow BD, Sosnov JA, Siew ED, Wickersham N, Latack W, Kwan HK, Heegard KD, Diaz C, Henderson AT, Saenz KK, Ikizler TA, Chung KK. The potential utility of urinary biomarkers for risk prediction in combat casualties: a prospective observational cohort study. Crit Care. 2015; 19: 252. PMID: 26077788, PMCID: PMC4487799, PII: 10.1186/s13054-015-0965-y, DOI: 10.1186/s13054-015-0965-y, ISSN: 1466-609X.

Rivara MB, Ikizler TA, Ellis CD, Mehrotra R, Himmelfarb J. Association of plasma F2-isoprostanes and isofurans concentrations with erythropoiesis-stimulating agent resistance in maintenance hemodialysis patients. BMC Nephrol. 2015; 16: 79. PMID: 26045064, PMCID: PMC4455324, PII: 10.1186/s12882-015-0074-9, DOI: 10.1186/s12882-015-0074-9, ISSN: 1471-2369.

Wright Nunes JA, Anderson CA, Greene JH, Ikizler TA, Cavanaugh KL. Results of a novel screening tool measuring dietary sodium knowledge in patients with chronic kidney disease. BMC Nephrol. 2015; 16: 42. PMID: 25880876, PMCID: PMC4387682, PII: 10.1186/s12882-015-0027-3, DOI: 10.1186/s12882-015-0027-3, ISSN: 1471-2369.

Rivara MB, Mehrotra R, Linke L, Ruzinski J, Ikizler TA, Himmelfarb J. A pilot randomized crossover trial assessing the safety and short-term effects of pomegranate supplementation in hemodialysis patients. J Ren Nutr [print-electronic]. 2015 Jan; 25(1): 40-9. PMID: 25218876, PMCID: PMC4282815, PII: S1051-2276(14)00126-5, DOI: 10.1053/j.jrn.2014.07.006, ISSN: 1532-8503.

Yeung CK, Billings FT, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J. Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. BMC Nephrol. 2015; 16: 183. PMID: 26531095, PMCID: PMC4630830, PII: 10.1186/s12882-015-0178-2, DOI: 10.1186/s12882-015-0178-2, ISSN: 1471-2369.

Shah B, Kirpalani A, Sunder S, Gupta A, Khanna U, Chafekar D, Tan LP, Sirivongs D, Pahari D, Nath G, Ikizler TA. A prospective, multi-centre, observational study to examine kidney disease progression in adults with chronic kidney disease - CKDOD - Study design and preliminary results. BMC Nephrol. 2015; 16: 215. PMID: 26696239, PMCID: PMC4687357, PII: 10.1186/s12882-015-0191-5, DOI: 10.1186/s12882-015-0191-5, ISSN: 1471-2369.

Akwo EA, Cavanaugh KL, Ikizler TA, Blot WJ, Lipworth L. Increased body mass index may be associated with greater risk of end-stage renal disease in whites compared to blacks: A nested case-control study. BMC Nutr [print-electronic]. 2015; 1: PMID: 27239330, PMCID: PMC4880028, DOI: 10.1186/s40795-015-0022-x, ISSN: 2055-0928.

Hung AM, Limkunakul C, Placido JS, Siew ED, Ellis CD, Shintani A, Ikizler TA. Administration of IL-1ra improves adiponectin levels in chronic hemodialysis patients. J. Nephrol [print-electronic]. 2014 Dec; 27(6): 681-8. PMID: 24609887, PII: 10.1007/s40620-014-0070-3, DOI: 10.1007/s40620-014-0070-3, ISSN: 1724-6059.

Ikizler TA, Wanner C. Total nutrition therapy renal: a clinical nutrition education program for nephrologists and other renal health care professionals. J Ren Nutr [print-electronic]. 2014 Nov; 24(6): 347-8. PMID: 25190486, PII: S1051-2276(14)00114-9, DOI: 10.1053/j.jrn.2014.06.006, ISSN: 1532-8503.

Ikizler TA. Using and interpreting serum albumin and prealbumin as nutritional markers in patients on chronic dialysis. Semin Dial [print-electronic]. 2014 Nov; 27(6): 590-2. PMID: 25138040, DOI: 10.1111/sdi.12288, ISSN: 1525-139X.

Martinson M, Ikizler TA, Morrell G, Wei G, Almeida N, Marcus RL, Filipowicz R, Greene TH, Beddhu S. Associations of body size and body composition with functional ability and quality of life in hemodialysis patients. Clin J Am Soc Nephrol [print-electronic]. 2014 Jun 6/6/2014; 9(6): 1082-90. PMID: 24763868, PMCID: PMC4046730, PII: CJN.09200913, DOI: 10.2215/CJN.09200913, ISSN: 1555-905X.

Limkunakul C, Sundell MB, Pouliot B, Graves AJ, Shintani A, Ikizler TA. Glycemic load is associated with oxidative stress among prevalent maintenance hemodialysis patients. Nephrol. Dial. Transplant [print-electronic]. 2014 May; 29(5): 1047-53. PMID: 24353320, PMCID: PMC4055829, PII: gft489, DOI: 10.1093/ndt/gft489, ISSN: 1460-2385.

Deger SM, Ellis CD, Bian A, Shintani A, Ikizler TA, Hung AM. Obesity, diabetes and survival in maintenance hemodialysis patients. Ren Fail [print-electronic]. 2014 May; 36(4): 546-51. PMID: 24467439, DOI: 10.3109/0886022X.2013.876351, ISSN: 1525-6049.

Ikizler TA, Franch HA, Kalantar-Zadeh K, ter Wee PM, Wanner C. Time to revisit the role of renal dietitian in the dialysis unit. J Ren Nutr. 2014 Jan; 24(1): 58-60. PMID: 24355820, PII: S1051-2276(13)00195-7, DOI: 10.1053/j.jrn.2013.10.006, ISSN: 1532-8503.

Byham-Gray L, Parrott JS, Ho WY, Sundell MB, Ikizler TA. Development of a predictive energy equation for maintenance hemodialysis patients: a pilot study. J Ren Nutr. 2014 Jan; 24(1): 32-41. PMID: 24355819, PMCID: PMC3883673, PII: S1051-2276(13)00194-5, DOI: 10.1053/j.jrn.2013.10.005, ISSN: 1532-8503.

Matheny ME, Peterson JF, Eden SK, Hung AM, Speroff T, Abdel-Kader K, Parr SK, Ikizler TA, Siew ED. Laboratory test surveillance following acute kidney injury. PLoS ONE. 2014; 9(8): e103746. PMID: 25117447, PMCID: PMC4130516, PII: PONE-D-14-10168, DOI: 10.1371/journal.pone.0103746, ISSN: 1932-6203.

Ikizler TA. A patient with CKD and poor nutritional status. Clin J Am Soc Nephrol [print-electronic]. 2013 Dec; 8(12): 2174-82. PMID: 23970134, PMCID: PMC3848406, PII: CJN.04630513, DOI: 10.2215/CJN.04630513, ISSN: 1555-905X.

Ikizler TA, Cano NJ, Franch H, Fouque D, Himmelfarb J, Kalantar-Zadeh K, Kuhlmann MK, Stenvinkel P, TerWee P, Teta D, Wang AY, Wanner C, . Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism. Kidney Int [print-electronic]. 2013 Dec; 84(6): 1096-107. PMID: 23698226, PII: S0085-2538(15)56097-3, DOI: 10.1038/ki.2013.147.

Tentori F, Karaboyas A, Robinson BM, Morgenstern H, Zhang J, Sen A, Ikizler TA, Rayner H, Fissell RB, Vanholder R, Tomo T, Port FK. Association of dialysate bicarbonate concentration with mortality in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am. J. Kidney Dis [print-electronic]. 2013 Oct; 62(4): 738-46. PMID: 23707043, PMCID: PMC3832240, PII: S0272-6386(13)00780-4, DOI: 10.1053/j.ajkd.2013.03.035, ISSN: 1523-6838.

Siew ED, Ware LB, Bian A, Shintani A, Eden SK, Wickersham N, Cripps B, Ikizler TA. Distinct injury markers for the early detection and prognosis of incident acute kidney injury in critically ill adults with preserved kidney function. Kidney Int [print-electronic]. 2013 Oct; 84(4): 786-94. PMID: 23698227, PMCID: PMC3788840, PII: S0085-2538(15)56029-8, DOI: 10.1038/ki.2013.174, ISSN: 1523-1755.

Cox ZL, McCoy AB, Matheny ME, Bhave G, Peterson NB, Siew ED, Lewis J, Danciu I, Bian A, Shintani A, Ikizler TA, Neal EB, Peterson JF. Adverse drug events during AKI and its recovery. Clin J Am Soc Nephrol [print-electronic]. 2013 Jul; 8(7): 1070-8. PMID: 23539228, PMCID: PMC3700703, PII: CJN.11921112, DOI: 10.2215/CJN.11921112, ISSN: 1555-905X.

Deger SM, Sundell MB, Siew ED, Egbert P, Ellis CD, Sha F, Ikizler TA, Hung AM. Insulin resistance and protein metabolism in chronic hemodialysis patients. J Ren Nutr [print-electronic]. 2013 May; 23(3): e59-66. PMID: 23194840, PMCID: PMC3852904, PII: S1051-2276(12)00198-7, DOI: 10.1053/j.jrn.2012.08.013, ISSN: 1532-8503.

Hung AM, Sundell MB, Plotnikova NE, Bian A, Shintani A, Ellis CD, Siew ED, Ikizler TA. A pilot study of active vitamin D administration and insulin resistance in African American patients undergoing chronic hemodialysis. J Ren Nutr [print-electronic]. 2013 May; 23(3): 185-93. PMID: 22959781, PMCID: PMC3519966, PII: S1051-2276(12)00143-4, DOI: 10.1053/j.jrn.2012.06.005, ISSN: 1532-8503.

Kon V, Ikizler TA, Fazio S. Importance of high-density lipoprotein quality: evidence from chronic kidney disease. Curr. Opin. Nephrol. Hypertens. 2013 May; 22(3): 259-65. PMID: 23470818, DOI: 10.1097/MNH.0b013e32835fe47f, ISSN: 1473-6543.

Cavanaugh KL, Ikizler TA. Acknowledging kidney disease: is ignorance salubrious? [editorial]. Am. J. Kidney Dis [print-electronic]. 2013 Apr; 61(4): 536-9. PMID: 23312722, PII: S0272-6386(12)01514-4, DOI: 10.1053/j.ajkd.2012.12.005, ISSN: 1523-6838.

Ikizler TA. Optimal nutrition in hemodialysis patients. Adv Chronic Kidney Dis. 2013 Mar; 20(2): 181-9. PMID: 23439378, PMCID: PMC3582995, PII: S1548-5595(12)00222-4, DOI: 10.1053/j.ackd.2012.12.002, ISSN: 1548-5609.

Buchowski MS, Simmons SF, Whitaker LE, Powers J, Beuscher L, Choi L, Ikizler TA, Chen K, Shnelle JF. Fatigability as a function of physical activity energy expenditure in older adults. Age (Dordr) [print-electronic]. 2013 Feb; 35(1): 179-87. PMID: 22113348, PMCID: PMC3543733, DOI: 10.1007/s11357-011-9338-x, ISSN: 1574-4647.

Siew ED, Peterson JF, Eden SK, Moons KG, Ikizler TA, Matheny ME. Use of multiple imputation method to improve estimation of missing baseline serum creatinine in acute kidney injury research. Clin J Am Soc Nephrol [print-electronic]. 2013 Jan; 8(1): 10-8. PMID: 23037980, PMCID: PMC3531649, PII: CJN.00200112, DOI: 10.2215/CJN.00200112, ISSN: 1555-905X.

Maripuri S, Ikizler TA, Cavanaugh KL. Prevalence of pre-end-stage renal disease care and associated outcomes among urban, micropolitan, and rural dialysis patients. Am. J. Nephrol [print-electronic]. 2013; 37(3): 274-80. PMID: 23548738, PMCID: PMC3787839, PII: 000348377, DOI: 10.1159/000348377, ISSN: 1421-9670.

Yamamoto S, Yancey PG, Ikizler TA, Jerome WG, Kaseda R, Cox B, Bian A, Shintani A, Fogo AB, Linton MF, Fazio S, Kon V. Dysfunctional high-density lipoprotein in patients on chronic hemodialysis. J. Am. Coll. Cardiol [print-electronic]. 2012 Dec 12/11/2012; 60(23): 2372-9. PMID: 23141484, PII: S0735-1097(12)04651-7, DOI: 10.1016/j.jacc.2012.09.013, ISSN: 1558-3597.

King-Morris K, Ikizler TA. Insulin resistance in patients undergoing peritoneal dialysis: can we improve it? : editorial to: "the effect of HM-CoA reductase inhibitor on insulin resistance in patients undergoing peritoneal dialysis" by Fa Mee Doh et al [editorial]. Cardiovasc Drugs Ther. 2012 Dec; 26(6): 441-3. PMID: 23161070, PMCID: PMC4118763, DOI: 10.1007/s10557-012-6423-z, ISSN: 1573-7241.

Schnelle JF, Buchowski MS, Ikizler TA, Durkin DW, Beuscher L, Simmons SF. Evaluation of two fatigability severity measures in elderly adults. J Am Geriatr Soc [print-electronic]. 2012 Aug; 60(8): 1527-33. PMID: 22860899, PMCID: PMC3419324, DOI: 10.1111/j.1532-5415.2012.04062.x, ISSN: 1532-5415.

Billings FT, Pretorius M, Schildcrout JS, Mercaldo ND, Byrne JG, Ikizler TA, Brown NJ. Obesity and oxidative stress predict AKI after cardiac surgery. J. Am. Soc. Nephrol [print-electronic]. 2012 Jul; 23(7): 1221-8. PMID: 22626819, PMCID: PMC3380645, PII: ASN.2011090940, DOI: 10.1681/ASN.2011090940, ISSN: 1533-3450.

Maripuri S, Arbogast P, Ikizler TA, Cavanaugh KL. Rural and micropolitan residence and mortality in patients on dialysis. Clin J Am Soc Nephrol [print-electronic]. 2012 Jul; 7(7): 1121-9. PMID: 22516293, PMCID: PMC3386672, PII: CJN.10831011, DOI: 10.2215/CJN.10831011, ISSN: 1555-905X.

Siew ED, Ikizler TA, Matheny ME, Shi Y, Schildcrout JS, Danciu I, Dwyer JP, Srichai M, Hung AM, Smith JP, Peterson JF. Estimating baseline kidney function in hospitalized patients with impaired kidney function. Clin J Am Soc Nephrol [print-electronic]. 2012 May; 7(5): 712-9. PMID: 22422536, PMCID: PMC3338282, PII: CJN.10821011, DOI: 10.2215/CJN.10821011, ISSN: 1555-905X.

Hung AM, Roumie CL, Greevy RA, Liu X, Grijalva CG, Murff HJ, Ikizler TA, Griffin MR. Comparative effectiveness of incident oral antidiabetic drugs on kidney function. Kidney Int [print-electronic]. 2012 Apr; 81(7): 698-706. PMID: 22258320, PMCID: PMC3306005, PII: ki2011444, DOI: 10.1038/ki.2011.444, ISSN: 1523-1755.

Siew ED, Peterson JF, Eden SK, Hung AM, Speroff T, Ikizler TA, Matheny ME. Outpatient nephrology referral rates after acute kidney injury. J. Am. Soc. Nephrol [print-electronic]. 2012 Feb; 23(2): 305-12. PMID: 22158435, PMCID: PMC3269178, PII: ASN.2011030315, DOI: 10.1681/ASN.2011030315, ISSN: 1533-3450.

Gamboa JL, Pretorius M, Todd-Tzanetos DR, Luther JM, Yu C, Ikizler TA, Brown NJ. Comparative effects of angiotensin-converting enzyme inhibition and angiotensin-receptor blockade on inflammation during hemodialysis. J. Am. Soc. Nephrol [print-electronic]. 2012 Feb; 23(2): 334-42. PMID: 22158433, PMCID: PMC3269170, PII: ASN.2011030287, DOI: 10.1681/ASN.2011030287, ISSN: 1533-3450.

Lipworth L, Mumma MT, Cavanaugh KL, Edwards TL, Ikizler TA, Tarone RE, McLaughlin JK, Blot WJ. Incidence and predictors of end stage renal disease among low-income blacks and whites. PLoS ONE [print-electronic]. 2012; 7(10): e48407. PMID: 23110237, PMCID: PMC3480508, PII: PONE-D-12-23038, DOI: 10.1371/journal.pone.0048407, ISSN: 1932-6203.

Birdwell KA, Ikizler MR, Wang L, Byrne DW, Sannella EC, Wright PF, Ikizler TA. Seasonal maintenance of influenza vaccine-induced antibody response in kidney transplant recipients. Am. J. Nephrol [print-electronic]. 2012; 36(3): 201-7. PMID: 22906930, PMCID: PMC3482977, PII: 000341653, DOI: 10.1159/000341653, ISSN: 1421-9670.

Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenet. Genomics. 2012 Jan; 22(1): 32-42. PMID: 22108237, PMCID: PMC3237759, DOI: 10.1097/FPC.0b013e32834e1641, ISSN: 1744-6880.

Wright Nunes JA, Wallston KA, Eden SK, Shintani AK, Ikizler TA, Cavanaugh KL. Associations among perceived and objective disease knowledge and satisfaction with physician communication in patients with chronic kidney disease. Kidney Int [print-electronic]. 2011 Dec; 80(12): 1344-51. PMID: 21832984, PMCID: PMC3712792, PII: ki2011240, DOI: 10.1038/ki.2011.240, ISSN: 1523-1755.

Chan KE, Ikizler TA, Gamboa JL, Yu C, Hakim RM, Brown NJ. Combined angiotensin-converting enzyme inhibition and receptor blockade associate with increased risk of cardiovascular death in hemodialysis patients. Kidney Int [print-electronic]. 2011 Nov; 80(9): 978-85. PMID: 21775975, PMCID: PMC3656595, PII: S0085-2538(15)55155-7, DOI: 10.1038/ki.2011.228, ISSN: 1523-1755.

Ikizler TA. Common nutritional misconceptions in dialysis patients. Semin Dial. 2011 Sep; 24(5): 510-2. PMID: 21999739, DOI: 10.1111/j.1525-139X.2011.00988.x, ISSN: 1525-139X.

Siew ED, Ware LB, Ikizler TA. Biological markers of acute kidney injury. J. Am. Soc. Nephrol [print-electronic]. 2011 May; 22(5): 810-20. PMID: 21493774, PII: ASN.2010080796, DOI: 10.1681/ASN.2010080796, ISSN: 1533-3450.

Ramos LF, Kane J, McMonagle E, Le P, Wu P, Shintani A, Ikizler TA, Himmelfarb J. Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease. J Ren Nutr [print-electronic]. 2011 May; 21(3): 211-8. PMID: 21185738, PMCID: PMC3078529, PII: S1051-2276(10)00227-X, DOI: 10.1053/j.jrn.2010.08.003, ISSN: 1532-8503.

Wright JA, Wallston KA, Elasy TA, Ikizler TA, Cavanaugh KL. Development and results of a kidney disease knowledge survey given to patients with CKD. Am. J. Kidney Dis [print-electronic]. 2011 Mar; 57(3): 387-95. PMID: 21168943, PMCID: PMC3053083, PII: S0272-6386(10)01440-X, DOI: 10.1053/j.ajkd.2010.09.018, ISSN: 1523-6838.

Hung AM, Ellis CD, Shintani A, Booker C, Ikizler TA. IL-1ß receptor antagonist reduces inflammation in hemodialysis patients. J. Am. Soc. Nephrol [print-electronic]. 2011 Mar; 22(3): 437-42. PMID: 21310819, PMCID: PMC3060437, PII: ASN.2010070760, DOI: 10.1681/ASN.2010070760, ISSN: 1533-3450.

Dong J, Sundell MB, Pupim LB, Wu P, Shintani A, Ikizler TA. The effect of resistance exercise to augment long-term benefits of intradialytic oral nutritional supplementation in chronic hemodialysis patients. J Ren Nutr [print-electronic]. 2011 Mar; 21(2): 149-59. PMID: 20580251, PMCID: PMC2947559, PII: S1051-2276(10)00075-0, DOI: 10.1053/j.jrn.2010.03.004, ISSN: 1532-8503.

Maripuri S, Penson DF, Ikizler TA, Cavanaugh KL. Outpatient versus inpatient observation after percutaneous native kidney biopsy: a cost minimization study. Am. J. Nephrol [print-electronic]. 2011; 34(1): 64-70. PMID: 21677428, PMCID: PMC3123742, PII: 000328901, DOI: 10.1159/000328901, ISSN: 1421-9670.

Hung AM, Ikizler TA, Griffin MR, Glenn K, Greevy RA, Grijalva CG, Siew ED, Crawford DC. CRP polymorphisms and chronic kidney disease in the third national health and nutrition examination survey. BMC Med. Genet. 2011; 12: 65. PMID: 21569369, PMCID: PMC3119179, PII: 1471-2350-12-65, DOI: 10.1186/1471-2350-12-65, ISSN: 1471-2350.

Ikizler TA. Exercise as an anabolic intervention in patients with end-stage renal disease. J Ren Nutr. 2011 Jan; 21(1): 52-6. PMID: 21195920, PMCID: PMC3061820, PII: S1051-2276(10)00287-6, DOI: 10.1053/j.jrn.2010.10.012, ISSN: 1532-8503.

Alves TP, Hulgan T, Wu P, Sterling TR, Stinnette SE, Rebeiro PF, Vincz AJ, Bruce M, Ikizler TA. Race, kidney disease progression, and mortality risk in HIV-infected persons. Clin J Am Soc Nephrol [print-electronic]. 2010 Dec; 5(12): 2269-75. PMID: 20876679, PMCID: PMC2994089, PII: CJN.00520110, DOI: 10.2215/CJN.00520110, ISSN: 1555-905X.

Cavanaugh KL, Wingard RL, Hakim RM, Eden S, Shintani A, Wallston KA, Huizinga MM, Elasy TA, Rothman RL, Ikizler TA. Low health literacy associates with increased mortality in ESRD. J. Am. Soc. Nephrol [print-electronic]. 2010 Nov; 21(11): 1979-85. PMID: 20671215, PMCID: PMC3014012, PII: ASN.2009111163, DOI: 10.1681/ASN.2009111163, ISSN: 1533-3450.

Matheny ME, Miller RA, Ikizler TA, Waitman LR, Denny JC, Schildcrout JS, Dittus RS, Peterson JF. Development of inpatient risk stratification models of acute kidney injury for use in electronic health records. Med Decis Making [print-electronic]. 2010 Nov; 30(6): 639-50. PMID: 20354229, PMCID: PMC4850549, PII: 0272989X10364246, DOI: 10.1177/0272989X10364246, ISSN: 1552-681X.

Smith K, Coston M, Glock K, Elasy TA, Wallston KA, Ikizler TA, Cavanaugh KL. Patient perspectives on fluid management in chronic hemodialysis. J Ren Nutr [print-electronic]. 2010 Sep; 20(5): 334-41. PMID: 19913443, PMCID: PMC2888683, PII: S1051-2276(09)00241-6, DOI: 10.1053/j.jrn.2009.09.001, ISSN: 1532-8503.

Siew ED, Ikizler TA, Gebretsadik T, Shintani A, Wickersham N, Bossert F, Peterson JF, Parikh CR, May AK, Ware LB. Elevated urinary IL-18 levels at the time of ICU admission predict adverse clinical outcomes. Clin J Am Soc Nephrol [print-electronic]. 2010 Aug; 5(8): 1497-505. PMID: 20558561, PMCID: PMC2924408, PII: CJN.09061209, DOI: 10.2215/CJN.09061209, ISSN: 1555-905X.

Siew ED, Ikizler TA. Insulin resistance and protein energy metabolism in patients with advanced chronic kidney disease. Semin Dial. 2010 Jul; 23(4): 378-82. PMID: 20701717, PII: SDI763, DOI: 10.1111/j.1525-139X.2010.00763.x, ISSN: 1525-139X.

Siew ED, Matheny ME, Ikizler TA, Lewis JB, Miller RA, Waitman LR, Go AS, Parikh CR, Peterson JF. Commonly used surrogates for baseline renal function affect the classification and prognosis of acute kidney injury. Kidney Int [print-electronic]. 2010 Mar; 77(6): 536-42. PMID: 20042998, PMCID: PMC2929703, PII: S0085-2538(15)54290-7, DOI: 10.1038/ki.2009.479, ISSN: 1523-1755.

Hung AM, Crawford DC, Griffin MR, Brown-Gentry K, Lipkowitz MS, Siew ED, Cavanaugh K, Lewis JB, Ikizler TA, . CRP polymorphisms and progression of chronic kidney disease in African Americans. Clin J Am Soc Nephrol [print-electronic]. 2010 Jan; 5(1): 24-33. PMID: 19965533, PMCID: PMC2801650, PII: CJN.01900309, DOI: 10.2215/CJN.01900309, ISSN: 1555-905X.

da Costa JA, Ikizler TA. Inflammation and insulin resistance as novel mechanisms of wasting in chronic dialysis patients. Semin Dial. 2009 Nov; 22(6): 652-7. PMID: 20017836, PII: SDI664, DOI: 10.1111/j.1525-139X.2009.00664.x, ISSN: 1525-139X.

Dong J, Ikizler TA. New insights into the role of anabolic interventions in dialysis patients with protein energy wasting. Curr. Opin. Nephrol. Hypertens. 2009 Nov; 18(6): 469-75. PMID: 19713839, PMCID: PMC2891019, DOI: 10.1097/MNH.0b013e328331489d, ISSN: 1473-6543.

Marney AM, Ma J, Luther JM, Ikizler TA, Brown NJ. Endogenous bradykinin contributes to increased plasminogen activator inhibitor 1 antigen following hemodialysis. J. Am. Soc. Nephrol [print-electronic]. 2009 Oct; 20(10): 2246-52. PMID: 19628666, PMCID: PMC2754101, PII: ASN.2009050505, DOI: 10.1681/ASN.2009050505, ISSN: 1533-3450.

Sundell MB, Cavanaugh KL, Wu P, Shintani A, Hakim RM, Ikizler TA. Oral protein supplementation alone improves anabolism in a dose-dependent manner in chronic hemodialysis patients. J Ren Nutr [print-electronic]. 2009 Sep; 19(5): 412-21. PMID: 19500999, PMCID: PMC2758490, PII: S1051-2276(09)00041-7, DOI: 10.1053/j.jrn.2009.01.019, ISSN: 1532-8503.

Siew ED, Ware LB, Gebretsadik T, Shintani A, Moons KG, Wickersham N, Bossert F, Ikizler TA. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J. Am. Soc. Nephrol [print-electronic]. 2009 Aug; 20(8): 1823-32. PMID: 19628673, PMCID: PMC2723988, PII: ASN.2008070673, DOI: 10.1681/ASN.2008070673, ISSN: 1533-3450.

Birdwell KA, Ikizler MR, Sannella EC, Wang L, Byrne DW, Ikizler TA, Wright PF. Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study. Am. J. Kidney Dis [print-electronic]. 2009 Jul; 54(1): 112-21. PMID: 19185404, PMCID: PMC3772511, PII: S0272-6386(08)01608-9, DOI: 10.1053/j.ajkd.2008.09.023, ISSN: 1523-6838.

Brunelli SM, Thadhani R, Ikizler TA, Feldman HI. Thiazolidinedione use is associated with better survival in hemodialysis patients with non-insulin dependent diabetes. Kidney Int [print-electronic]. 2009 May; 75(9): 961-8. PMID: 19190679, PMCID: PMC2864092, PII: ki20094, DOI: 10.1038/ki.2009.4, ISSN: 1523-1755.

Ramos LF, Shintani A, Himmelfarb J, Ikizler TA. Determinants of plasma adiponectin levels in nondiabetic subjects with moderate to severe chronic kidney disease. J Ren Nutr. 2009 May; 19(3): 197-203. PMID: 19393918, PII: S1051-2276(09)00050-8, DOI: 10.1053/j.jrn.2009.01.028, ISSN: 1532-8503.

Cavanaugh KL, Wingard RL, Hakim RM, Elasy TA, Ikizler TA. Patient dialysis knowledge is associated with permanent arteriovenous access use in chronic hemodialysis. Clin J Am Soc Nephrol [print-electronic]. 2009 May; 4(5): 950-6. PMID: 19389825, PMCID: PMC2676183, PII: CJN.04580908, DOI: 10.2215/CJN.04580908, ISSN: 1555-905X.

Ikizler TA. Dietary protein restriction in CKD: the debate continues [editorial]. Am. J. Kidney Dis. 2009 Feb; 53(2): 189-91. PMID: 19166797, PII: S0272-6386(08)01749-6, DOI: 10.1053/j.ajkd.2008.12.014, ISSN: 1523-6838.

Ikizler TA. Nutrition support for the chronically wasted or acutely catabolic chronic kidney disease patient. Semin. Nephrol. 2009 Jan; 29(1): 75-84. PMID: 19121477, PMCID: PMC3788638, PII: S0270-9295(08)00173-3, DOI: 10.1016/j.semnephrol.2008.10.011, ISSN: 0270-9295.

Kopple JD, Cheung AK, Christiansen JS, Djurhuus CB, El Nahas M, Feldt-Rasmussen B, Lange M, Mitch WE, Wanner C, Wiedemann J, Ikizler TA. OPPORTUNITY: a randomized clinical trial of growth hormone on outcome in hemodialysis patients. Clin J Am Soc Nephrol. 2008 Nov; 3(6): 1741-51. PMID: 18945992, PMCID: PMC2572295, PII: CJN.02760608, DOI: 10.2215/CJN.02760608, ISSN: 1555-905X.

Mehrotra R, Martin KJ, Fishbane S, Sprague SM, Zeig S, Anger M, . Higher strength lanthanum carbonate provides serum phosphorus control with a low tablet burden and is preferred by patients and physicians: a multicenter study. Clin J Am Soc Nephrol [print-electronic]. 2008 Sep; 3(5): 1437-45. PMID: 18579668, PMCID: PMC2518797, PII: CJN.04741107, DOI: 10.2215/CJN.04741107, ISSN: 1555-905X.

Hung AM, Ikizler TA. Hemodialysis central venous catheters as a source of inflammation and its implications [editorial]. Semin Dial [print-electronic]. 2008 Sep; 21(5): 401-4. PMID: 18573135, PII: SDI444, DOI: 10.1111/j.1525-139X.2008.00444.x, ISSN: 1525-139X.

Crowley ST, Chertow GM, Vitale J, O'Connor T, Zhang J, Schein RM, Choudhury D, Finkel K, Vijayan A, Paganini E, Palevsky PM, . Lessons for successful study enrollment from the Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study. Clin J Am Soc Nephrol [print-electronic]. 2008 Jul; 3(4): 955-61. PMID: 18385390, PMCID: PMC2440269, PII: CJN.05621207, DOI: 10.2215/CJN.05621207, ISSN: 1555-905X.

Ikizler TA. Resolved: being fat is good for dialysis patients: the Godzilla effect: pro. J. Am. Soc. Nephrol [print-electronic]. 2008 Jun; 19(6): 1059-62. PMID: 18256355, PII: ASN.2007090983, DOI: 10.1681/ASN.2007090983, ISSN: 1533-3450.

Dember LM, Beck GJ, Allon M, Delmez JA, Dixon BS, Greenberg A, Himmelfarb J, Vazquez MA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI, . Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial. JAMA. 2008 May 5/14/2008; 299(18): 2164-71. PMID: 18477783, PII: 299/18/2164, DOI: 10.1001/jama.299.18.2164, ISSN: 1538-3598.

Majchrzak KM, Pupim LB, Flakoll PJ, Ikizler TA. Resistance exercise augments the acute anabolic effects of intradialytic oral nutritional supplementation. Nephrol. Dial. Transplant [print-electronic]. 2008 Apr; 23(4): 1362-9. PMID: 18065829, PII: gfm773, DOI: 10.1093/ndt/gfm773, ISSN: 1460-2385.

Hung A, Pupim L, Yu C, Shintani A, Siew E, Ayus C, Hakim RM, Ikizler TA. Determinants of C-reactive protein in chronic hemodialysis patients: relevance of dialysis catheter utilization. Hemodial Int. 2008 Apr; 12(2): 236-43. PMID: 18394058, PII: HDI260, DOI: 10.1111/j.1542-4758.2008.00260.x, ISSN: 1492-7535.

Ikizler TA. Nutrition, inflammation and chronic kidney disease. Curr. Opin. Nephrol. Hypertens. 2008 Mar; 17(2): 162-7. PMID: 18277149, PII: 00041552-200803000-00008, DOI: 10.1097/MNH.0b013e3282f5dbce, ISSN: 1062-4821.

Ramos LF, Shintani A, Ikizler TA, Himmelfarb J. Oxidative stress and inflammation are associated with adiposity in moderate to severe CKD. J. Am. Soc. Nephrol [print-electronic]. 2008 Mar; 19(3): 593-9. PMID: 18256365, PMCID: PMC2391046, PII: ASN.2007030355, DOI: 10.1681/ASN.2007030355, ISSN: 1533-3450.

Fouque D, Kalantar-Zadeh K, Kopple J, Cano N, Chauveau P, Cuppari L, Franch H, Guarnieri G, Ikizler TA, Kaysen G, Lindholm B, Massy Z, Mitch W, Pineda E, Stenvinkel P, Treviño-Becerra A, Wanner C. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int [print-electronic]. 2008 Feb; 73(4): 391-8. PMID: 18094682, PII: 5002585, DOI: 10.1038/sj.ki.5002585, ISSN: 1523-1755.

Ikizler TA. Parenteral nutrition offers no benefit over oral supplementation in malnourished hemodialysis patients. Nat Clin Pract Nephrol [print-electronic]. 2008 Feb; 4(2): 76-7. PMID: 17998928, PII: ncpneph0675, DOI: 10.1038/ncpneph0675, ISSN: 1745-8331.

Caglar K, Yilmaz MI, Saglam M, Cakir E, Kilic S, Sonmez A, Eyileten T, Yenicesu M, Oguz Y, Tasar M, Vural A, Ikizler TA, Stenvinkel P, Lindholm B. Serum fetuin-a concentration and endothelial dysfunction in chronic kidney disease. Nephron Clin Pract [print-electronic]. 2008; 108(3): c233-40. PMID: 18334823, PII: 000120209, DOI: 10.1159/000120209, ISSN: 1660-2110.

Siew ED, Ikizler TA. Determinants of insulin resistance and its effects on protein metabolism in patients with advanced chronic kidney disease. Contrib Nephrol. 2008; 161: 138-44. PMID: 18451670, PII: 130659, DOI: 10.1159/000130659, ISSN: 0302-5144.

Trirogoff ML, Shintani A, Himmelfarb J, Ikizler TA. Body mass index and fat mass are the primary correlates of insulin resistance in nondiabetic stage 3-4 chronic kidney disease patients. Am. J. Clin. Nutr. 2007 Dec; 86(6): 1642-8. PMID: 18065581, PII: 86/6/1642, ISSN: 0002-9165.

Lacson E, Ikizler TA, Lazarus JM, Teng M, Hakim RM. Potential impact of nutritional intervention on end-stage renal disease hospitalization, death, and treatment costs. J Ren Nutr. 2007 Nov; 17(6): 363-71. PMID: 17971308, PII: S1051-2276(07)00177-X, DOI: 10.1053/j.jrn.2007.08.009, ISSN: 1532-8503.

Wingard RL, Pupim LB, Krishnan M, Shintani A, Ikizler TA, Hakim RM. Early intervention improves mortality and hospitalization rates in incident hemodialysis patients: RightStart program. Clin J Am Soc Nephrol [print-electronic]. 2007 Nov; 2(6): 1170-5. PMID: 17942761, PII: CJN.04261206, DOI: 10.2215/CJN.04261206, ISSN: 1555-905X.

Lacson E, Lazarus JM, Himmelfarb J, Ikizler TA, Hakim RM. Balancing Fistula First with Catheters Last. Am. J. Kidney Dis. 2007 Sep; 50(3): 379-95. PMID: 17720517, PII: S0272-6386(07)00926-2, DOI: 10.1053/j.ajkd.2007.06.006, ISSN: 1523-6838.

Himmelfarb J, Phinney S, Ikizler TA, Kane J, McMonagle E, Miller G. Gamma-tocopherol and docosahexaenoic acid decrease inflammation in dialysis patients. J Ren Nutr. 2007 Sep; 17(5): 296-304. PMID: 17720098, PII: S1051-2276(07)00112-4, DOI: 10.1053/j.jrn.2007.05.011, ISSN: 1532-8503.

Majchrzak KM, Pupim LB, Sundell M, Ikizler TA. Body composition and physical activity in end-stage renal disease. J Ren Nutr. 2007 May; 17(3): 196-204. PMID: 17462552, PMCID: PMC2746570, PII: S1051-2276(07)00002-7, DOI: 10.1053/j.jrn.2007.01.003, ISSN: 1532-8503.

Himmelfarb J, Ikizler TA. Acute kidney injury: changing lexicography, definitions, and epidemiology. Kidney Int [print-electronic]. 2007 May; 71(10): 971-6. PMID: 17396117, PII: 5002224, DOI: 10.1038/sj.ki.5002224, ISSN: 0085-2538.

Pupim LB, Flakoll PJ, Ikizler TA. Exercise improves albumin fractional synthetic rate in chronic hemodialysis patients. Eur J Clin Nutr [print-electronic]. 2007 May; 61(5): 686-9. PMID: 17180156, PII: 1602578, DOI: 10.1038/sj.ejcn.1602578, ISSN: 0954-3007.

Ikizler TA. Effects of glucose homeostasis on protein metabolism in patients with advanced chronic kidney disease. J Ren Nutr. 2007 Jan; 17(1): 13-6. PMID: 17198926, PII: S1051-2276(06)00230-5, DOI: 10.1053/j.jrn.2006.10.004, ISSN: 1532-8503.

Siew ED, Pupim LB, Majchrzak KM, Shintani A, Flakoll PJ, Ikizler TA. Insulin resistance is associated with skeletal muscle protein breakdown in non-diabetic chronic hemodialysis patients. Kidney Int [print-electronic]. 2007 Jan; 71(2): 146-52. PMID: 17063174, PII: 5001984, DOI: 10.1038/sj.ki.5001984, ISSN: 0085-2538.

Ikizler TA. Protein and energy intake in advanced chronic kidney disease: how much is too much? [editorial]. Semin Dial. 2007 Jan; 20(1): 5-11. PMID: 17244111, PII: SDI231, DOI: 10.1111/j.1525-139X.2007.00231.x, ISSN: 0894-0959.

Ikizler TA, Himmelfarb J. Trials and trade-offs in haemodialysis vascular access monitoring [editorial]. Nephrol. Dial. Transplant [print-electronic]. 2006 Dec; 21(12): 3362-3. PMID: 17005532, PII: gfl562, DOI: 10.1093/ndt/gfl562, ISSN: 0931-0509.

Pupim LB, Majchrzak KM, Flakoll PJ, Ikizler TA. Intradialytic oral nutrition improves protein homeostasis in chronic hemodialysis patients with deranged nutritional status. J. Am. Soc. Nephrol [print-electronic]. 2006 Nov; 17(11): 3149-57. PMID: 17021267, PII: ASN.2006040413, DOI: 10.1681/ASN.2006040413, ISSN: 1046-6673.

Cho KC, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM. Survival by dialysis modality in critically ill patients with acute kidney injury. J. Am. Soc. Nephrol [print-electronic]. 2006 Nov; 17(11): 3132-8. PMID: 17021268, PII: ASN.2006030268, DOI: 10.1681/ASN.2006030268, ISSN: 1046-6673.

Liu KD, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM. Timing of initiation of dialysis in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol [print-electronic]. 2006 Sep; 1(5): 915-9. PMID: 17699307, PII: CJN.01430406, DOI: 10.2215/CJN.01430406, ISSN: 1555-905X.

Chertow GM, Soroko SH, Paganini EP, Cho KC, Himmelfarb J, Ikizler TA, Mehta RL. Mortality after acute renal failure: models for prognostic stratification and risk adjustment. Kidney Int [print-electronic]. 2006 Sep; 70(6): 1120-6. PMID: 16850028, PII: 5001579, DOI: 10.1038/sj.ki.5001579, ISSN: 0085-2538.

Ikizler TA, Himmelfarb J. Muscle wasting in kidney disease: Let's get physical [editorial]. J. Am. Soc. Nephrol [print-electronic]. 2006 Aug; 17(8): 2097-8. PMID: 16837638, PII: ASN.2006060629, DOI: 10.1681/ASN.2006060629, ISSN: 1046-6673.

Pupim LB, Cuppari L, Ikizler TA. Nutrition and metabolism in kidney disease. Semin. Nephrol. 2006 Mar; 26(2): 134-57. PMID: 16530606, PII: S0270-9295(05)00187-7, DOI: 10.1016/j.semnephrol.2005.09.010, ISSN: 0270-9295.

Yilmaz MI, Korkmaz A, Kaya A, Sonmez A, Caglar K, Topal T, Eyileten T, Yenicesu M, Acikel C, Oter S, Yaman H, Aktug H, Oguz Y, Vural A, Ikizler TA. Hyperbaric oxygen treatment augments the efficacy of a losartan regime in an experimental nephrotic syndrome model. Nephron Exp. Nephrol [print-electronic]. 2006; 104(1): e15-22. PMID: 16699289, PII: 93260, DOI: 10.1159/000093260, ISSN: 1660-2129.

Pupim LB, Flakoll PJ, Yu C, Ikizler TA. Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients. Am. J. Clin. Nutr. 2005 Dec; 82(6): 1235-43. PMID: 16332656, PII: 82/6/1235, ISSN: 0002-9165.

Ikizler TA, Schulman G. Hemodialysis: techniques and prescription. Am. J. Kidney Dis. 2005 Nov; 46(5): 976-81. PMID: 16253743, PII: S0272-6386(05)01048-6, DOI: 10.1053/j.ajkd.2005.07.037, ISSN: 1523-6838.

Pupim LB, Heimbürger O, Qureshi AR, Ikizler TA, Stenvinkel P. Accelerated lean body mass loss in incident chronic dialysis patients with diabetes mellitus. Kidney Int. 2005 Nov; 68(5): 2368-74. PMID: 16221242, PII: KID699, DOI: 10.1111/j.1523-1755.2005.00699.x, ISSN: 0085-2538.

Pupim LB, Flakoll PJ, Majchrzak KM, Aftab Guy DL, Stenvinkel P, Ikizler TA. Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus. Kidney Int. 2005 Oct; 68(4): 1857-65. PMID: 16164664, PII: KID605, DOI: 10.1111/j.1523-1755.2005.00605.x, ISSN: 0085-2538.

Basi S, Pupim LB, Simmons EM, Sezer MT, Shyr Y, Freedman S, Chertow GM, Mehta RL, Paganini E, Himmelfarb J, Ikizler TA. Insulin resistance in critically ill patients with acute renal failure. Am. J. Physiol. Renal Physiol [print-electronic]. 2005 Aug; 289(2): F259-64. PMID: 15840772, PII: 00002.2005, DOI: 10.1152/ajprenal.00002.2005, ISSN: 1931-857X.

Yenicesu M, Yilmaz MI, Caglar K, Sonmez A, Eyileten T, Kir T, Acikel C, Bingol N, Oguz Y, Ikizler TA, Vural A. Adiponectin level is reduced and inversely correlated with the degree of proteinuria in type 2 diabetic patients. Clin. Nephrol. 2005 Jul; 64(1): 12-9. PMID: 16047640, ISSN: 0301-0430.

Simmons EM, Langone A, Sezer MT, Vella JP, Recupero P, Morrow JD, Ikizler TA, Himmelfarb J. Effect of renal transplantation on biomarkers of inflammation and oxidative stress in end-stage renal disease patients. Transplantation. 2005 Apr 4/27/2005; 79(8): 914-9. PMID: 15849543, PII: 00007890-200504270-00008, ISSN: 0041-1337.

Majchrzak KM, Pupim LB, Chen K, Martin CJ, Gaffney S, Greene JH, Ikizler TA. Physical activity patterns in chronic hemodialysis patients: comparison of dialysis and nondialysis days. J Ren Nutr. 2005 Apr; 15(2): 217-24. PMID: 15827895, PII: S1051227604001372, ISSN: 1532-8503.

Lim VS, Ikizler TA, Raj DS, Flanigan MJ. Does hemodialysis increase protein breakdown? Dissociation between whole-body amino acid turnover and regional muscle kinetics. J. Am. Soc. Nephrol [print-electronic]. 2005 Apr; 16(4): 862-8. PMID: 15716333, PII: ASN.2004080624, DOI: 10.1681/ASN.2004080624, ISSN: 1046-6673.

Ikizler TA. Effects of hemodialysis on protein metabolism. J Ren Nutr. 2005 Jan; 15(1): 39-43. PMID: 15648005, PII: S1051227604001761, ISSN: 1532-8503.

Himmelfarb J, Le P, Klenzak J, Freedman S, McMenamin ME, Ikizler TA, . Impaired monocyte cytokine production in critically ill patients with acute renal failure. Kidney Int. 2004 Dec; 66(6): 2354-60. PMID: 15569326, PII: KID66023, DOI: 10.1111/j.1523-1755.2004.66023.x, ISSN: 0085-2538.

Ikizler TA. Protein and energy: recommended intake and nutrient supplementation in chronic dialysis patients. Semin Dial. 2004 Nov; 17(6): 471-8. PMID: 15660578, PII: SDI17608, DOI: 10.1111/j.0894-0959.2004.17608.x, ISSN: 0894-0959.

Pupim LB, Caglar K, Hakim RM, Shyr Y, Ikizler TA. Uremic malnutrition is a predictor of death independent of inflammatory status. Kidney Int. 2004 Nov; 66(5): 2054-60. PMID: 15496179, PII: KID978, DOI: 10.1111/j.1523-1755.2004.00978.x, ISSN: 0085-2538.

Mehta RL, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler TA, Paganini EP, Chertow GM, . Spectrum of acute renal failure in the intensive care unit: the PICARD experience. Kidney Int. 2004 Oct; 66(4): 1613-21. PMID: 15458458, PII: KID927, DOI: 10.1111/j.1523-1755.2004.00927.x, ISSN: 0085-2538.

Himmelfarb J, McMonagle E, Freedman S, Klenzak J, McMenamin E, Le P, Pupim LB, Ikizler TA, The PICARD Group. Oxidative stress is increased in critically ill patients with acute renal failure. J. Am. Soc. Nephrol. 2004 Sep; 15(9): 2449-56. PMID: 15339994, PII: 15/9/2449, DOI: 10.1097/01.ASN.0000138232.68452.3B, ISSN: 1046-6673.

Pupim LB, Flakoll PJ, Ikizler TA. Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients. J. Am. Soc. Nephrol. 2004 Jul; 15(7): 1920-6. PMID: 15213282, ISSN: 1046-6673.

Pupim LB, Himmelfarb J, McMonagle E, Shyr Y, Ikizler TA. Influence of initiation of maintenance hemodialysis on biomarkers of inflammation and oxidative stress. Kidney Int. 2004 Jun; 65(6): 2371-9. PMID: 15149350, PII: KID656, DOI: 10.1111/j.1523-1755.2004.00656.x, ISSN: 0085-2538.

Pupim LB, Flakoll PJ, Levenhagen DK, Ikizler TA. Exercise augments the acute anabolic effects of intradialytic parenteral nutrition in chronic hemodialysis patients. Am. J. Physiol. Endocrinol. Metab [print-electronic]. 2004 Apr; 286(4): E589-97. PMID: 14678952, PII: 00384.2003, DOI: 10.1152/ajpendo.00384.2003, ISSN: 0193-1849.

Ikizler TA. Role of nutrition for cardiovascular risk reduction in chronic kidney disease patients. Adv Chronic Kidney Dis. 2004 Apr; 11(2): 162-71. PMID: 15216487, PII: S1548559504000096, ISSN: 1548-5595.

Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, Soroko S, Freedman S, Becker K, Spratt D, Shyr Y, Ikizler TA, . Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int. 2004 Apr; 65(4): 1357-65. PMID: 15086475, DOI: 10.1111/j.1523-1755.2004.00512.x, ISSN: 0085-2538.

Eustace JA, Astor B, Muntner PM, Ikizler TA, Coresh J. Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease. Kidney Int. 2004 Mar; 65(3): 1031-40. PMID: 14871424, DOI: 10.1111/j.1523-1755.2004.00481.x, ISSN: 0085-2538.

Oberg BP, McMenamin E, Lucas FL, McMonagle E, Morrow J, Ikizler TA, Himmelfarb J. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int. 2004 Mar; 65(3): 1009-16. PMID: 14871421, DOI: 10.1111/j.1523-1755.2004.00465.x, ISSN: 0085-2538.

Ikizler TA, Sezer MT, Flakoll PJ, Hariachar S, Kanagasundaram NS, Gritter N, Knights S, Shyr Y, Paganini E, Hakim RM, Himmelfarb J, . Urea space and total body water measurements by stable isotopes in patients with acute renal failure. Kidney Int. 2004 Feb; 65(2): 725-32. PMID: 14717948, DOI: 10.1111/j.1523-1755.2004.00439.x, ISSN: 0085-2538.

Flakoll PJ, Kent P, Neyra R, Levenhagen D, Chen KY, Ikizler TA. Bioelectrical impedance vs air displacement plethysmography and dual-energy X-ray absorptiometry to determine body composition in patients with end-stage renal disease. JPEN J Parenter Enteral Nutr. 2004 Jan; 28(1): 13-21. PMID: 14763788, ISSN: 0148-6071.

Pupim LB, Ikizler TA. Assessment and monitoring of uremic malnutrition. J Ren Nutr. 2004 Jan; 14(1): 6-19. PMID: 14740325, PII: S1051227603001808, ISSN: 1532-8503.

Pupim LB, Flakoll PJ, Ikizler TA. Protein homeostasis in chronic hemodialysis patients. Curr Opin Clin Nutr Metab Care. 2004 Jan; 7(1): 89-95. PMID: 15090908, PII: 00075197-200401000-00014, ISSN: 1363-1950.

Kalantar-Zadeh K, Ikizler TA, Block G, Avram MM, Kopple JD. Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences. Am. J. Kidney Dis. 2003 Nov; 42(5): 864-81. PMID: 14582032, PII: S0272638603010059, ISSN: 1523-6838.

Pupim LB, Evanson JA, Hakim RM, Ikizler TA. The extent of uremic malnutrition at the time of initiation of maintenance hemodialysis is associated with subsequent hospitalization. J Ren Nutr. 2003 Oct; 13(4): 259-66. PMID: 14566762, PII: S1051227603001043, ISSN: 1532-8503.

Chertow GM, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL, . Reasons for non-enrollment in a cohort study of ARF: the Program to Improve Care in Acute Renal Disease (PICARD) experience and implications for a clinical trials network. Am. J. Kidney Dis. 2003 Sep; 42(3): 507-12. PMID: 12955678, PII: S0272638603007455, ISSN: 1523-6838.

Danielski M, Ikizler TA, McMonagle E, Kane JC, Pupim L, Morrow J, Himmelfarb J. Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy. Am. J. Kidney Dis. 2003 Aug; 42(2): 286-94. PMID: 12900810, PII: S027263860300653X, ISSN: 1523-6838.

Pupim LB, Ikizler TA. Uremic malnutrition: new insights into an old problem. Semin Dial. 2003 May; 16(3): 224-32. PMID: 12753685, PII: 16046, ISSN: 0894-0959.

Yildiz A, Oflaz H, Pusuroglu H, Mercanoglu F, Genchallac H, Akkaya V, Ikizler TA, Sever MS. Left ventricular hypertrophy and endothelial dysfunction in chronic hemodialysis patients. Am. J. Kidney Dis. 2003 Mar; 41(3): 616-23. PMID: 12612985, PII: S0272638602692303, DOI: 10.1053/ajkd.2003.50123, ISSN: 1523-6838.

Neyra R, Chen KY, Sun M, Shyr Y, Hakim RM, Ikizler TA. Increased resting energy expenditure in patients with end-stage renal disease. JPEN J Parenter Enteral Nutr. 2003 Jan; 27(1): 36-42. PMID: 12549596, ISSN: 0148-6071.

Caglar K, Hakim RM, Ikizler TA. Approaches to the reversal of malnutrition, inflammation, and atherosclerosis in end-stage renal disease. Nutr. Rev. 2002 Nov; 60(11): 378-87. PMID: 12462522, ISSN: 0029-6643.

Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int. 2002 Nov; 62(5): 1524-38. PMID: 12371953, PII: kid600, DOI: 10.1046/j.1523-1755.2002.00600.x, ISSN: 0085-2538.

Caglar K, Peng Y, Pupim LB, Flakoll PJ, Levenhagen D, Hakim RM, Ikizler TA. Inflammatory signals associated with hemodialysis. Kidney Int. 2002 Oct; 62(4): 1408-16. PMID: 12234313, PII: kid556, DOI: 10.1111/j.1523-1755.2002.kid556.x, ISSN: 0085-2538.

Ikizler TA, Morrow JD, Roberts LJ, Evanson JA, Becker B, Hakim RM, Shyr Y, Himmelfarb J. Plasma F2-isoprostane levels are elevated in chronic hemodialysis patients. Clin. Nephrol. 2002 Sep; 58(3): 190-7. PMID: 12356187, ISSN: 0301-0430.

Caglar K, Fedje L, Dimmitt R, Hakim RM, Shyr Y, Ikizler TA. Therapeutic effects of oral nutritional supplementation during hemodialysis. Kidney Int. 2002 Sep; 62(3): 1054-9. PMID: 12164890, PII: kid530, DOI: 10.1046/j.1523-1755.2002.00530.x, ISSN: 0085-2538.

Pupim LB, Flakoll PJ, Brouillette JR, Levenhagen DK, Hakim RM, Ikizler TA. Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients. J. Clin. Invest. 2002 Aug; 110(4): 483-92. PMID: 12189242, PMCID: PMC150418, DOI: 10.1172/JCI15449, ISSN: 0021-9738.

Pupim LB, Kent P, Caglar K, Shyr Y, Hakim RM, Ikizler TA. Improvement in nutritional parameters after initiation of chronic hemodialysis. Am. J. Kidney Dis. 2002 Jul; 40(1): 143-51. PMID: 12087572, PII: S0272-6386(02)00018-5, DOI: 10.1053/ajkd.2002.33923, ISSN: 1523-6838.

Ikizler TA. Epidemiology of vascular disease in renal failure. Blood Purif. 2002; 20(1): 6-10. PMID: 11803153, PII: bpu20006, ISSN: 0253-5068.

Himmelfarb J, Evanson J, Hakim RM, Freedman S, Shyr Y, Ikizler TA. Urea volume of distribution exceeds total body water in patients with acute renal failure. Kidney Int. 2002 Jan; 61(1): 317-23. PMID: 11786114, PII: kid118, DOI: 10.1046/j.1523-1755.2002.00118.x, ISSN: 0085-2538.

Ikizler TA, Pupim LB, Brouillette JR, Levenhagen DK, Farmer K, Hakim RM, Flakoll PJ. Hemodialysis stimulates muscle and whole body protein loss and alters substrate oxidation. Am. J. Physiol. Endocrinol. Metab. 2002 Jan; 282(1): E107-16. PMID: 11739090, ISSN: 0193-1849.

Saadeh E, Ikizler TA, Shyr Y, Hakim RM, Himmelfarb J. Recombinant human growth hormone in patients with acute renal failure. J Ren Nutr. 2001 Oct; 11(4): 212-9. PMID: 11680002, PII: S1051227601815582, ISSN: 1051-2276.

McCarley P, Wingard RL, Shyr Y, Pettus W, Hakim RM, Ikizler TA. Vascular access blood flow monitoring reduces access morbidity and costs. Kidney Int. 2001 Sep; 60(3): 1164-72. PMID: 11532113, PII: kid914, DOI: 10.1046/j.1523-1755.2001.0600031164.x, ISSN: 0085-2538.

Hakim RM, Ikizler TA. Use of vascular access blood flow to evaluate vascular access [letter]. Am. J. Kidney Dis. 2001 Feb; 37(2): 451-2. PMID: 11157393, PII: S0272638601620973, ISSN: 1523-6838.

T. Alp Ikizler. Nutrition and Renal Failure. Primer in Kidney Diseases 3rd edition Greenberg Editor. 2001; 3rd Ed.: 420-5.

Neyra NR, Hakim RM, Shyr Y, Ikizler TA. Serum transferrin and serum prealbumin are early predictors of serum albumin in chronic hemodialysis patients. J Ren Nutr. 2000 Oct; 10(4): 184-90. PMID: 11070145, PII: S1051227600471487, ISSN: 1051-2276.

Bergström J, Lindholm B, Lacson E, Owen W, Lowrie EG, Glassock RJ, Ikizler TA, Wessels FJ, Moldawer LL, Wanner C, Zimmermann J. What are the causes and consequences of the chronic inflammatory state in chronic dialysis patients?. Semin Dial. 2000 May; 13(3): 163-75. PMID: 10833777, ISSN: 0894-0959.

Himmelfarb J, Ikizler TA. Quantitating urea removal in patients with acute renal failure: lost art or forgotten science?. Semin Dial. 2000 May; 13(3): 147-9. PMID: 10833772, ISSN: 0894-0959.

Matsuo K, Ikizler TA, Hoover RL, Nakamoto M, Yasunaga C, Pupim LB, Hakim RM. Transforming growth factor-beta is involved in the pathogenesis of dialysis-related amyloidosis. Kidney Int. 2000 Feb; 57(2): 697-708. PMID: 10652049, PII: kid892, DOI: 10.1046/j.1523-1755.2000.00892.x, ISSN: 0085-2538.

T. Alp Ikizler and Jonathan Himmelfarb. Nutritional Complications in Chronic Hemo- and Peritoneal Dialysis Patients In Complications of Dialysis. Mehta & Lamiere Editors. 2000.

T. Alp Ikizler and Raymond M. Hakim. Parenteral Nutrition and Renal failure. Clinical Nutrition: Parenteral Nutrition Rombeau and Rolandelli Editors. 2000; 3rd Ed.

Rehman SU, Pupim LB, Shyr Y, Hakim R, Ikizler TA. Intradialytic serial vascular access flow measurements. Am. J. Kidney Dis. 1999 Sep; 34(3): 471-7. PMID: 10469857, PII: S0272-6386(99)70074-0, DOI: 10.1053/AJKD03400471, ISSN: 1523-6838.

Pupim LB, Kent P, Ikizler TA. Bioelectrical impedance analysis in dialysis patients. Miner Electrolyte Metab. 1999 Jul; 25(4-6): 400-6. PMID: 10681674, PII: 57482, DOI: 57482, ISSN: 0378-0392.

Ikizler TA, Wingard RL, Harvell J, Shyr Y, Hakim RM. Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: a prospective study. Kidney Int. 1999 May; 55(5): 1945-51. PMID: 10231458, DOI: 10.1046/j.1523-1755.1999.00410.x, ISSN: 0085-2538.

Evanson JA, Ikizler TA, Wingard R, Knights S, Shyr Y, Schulman G, Himmelfarb J, Hakim RM. Measurement of the delivery of dialysis in acute renal failure. Kidney Int. 1999 Apr; 55(4): 1501-8. PMID: 10201016, DOI: 10.1046/j.1523-1755.1999.00355.x, ISSN: 0085-2538.

Neyra NR, Ikizler TA, May RE, Himmelfarb J, Schulman G, Shyr Y, Hakim RM. Change in access blood flow over time predicts vascular access thrombosis. Kidney Int. 1998 Nov; 54(5): 1714-9. PMID: 9844149, DOI: 10.1046/j.1523-1755.1998.00145.x, ISSN: 0085-2538.

Evanson JA, Himmelfarb J, Wingard R, Knights S, Shyr Y, Schulman G, Ikizler TA, Hakim RM. Prescribed versus delivered dialysis in acute renal failure patients. Am. J. Kidney Dis. 1998 Nov; 32(5): 731-8. PMID: 9820441, PII: S0272638698003102, ISSN: 1523-6838.

May RE, Himmelfarb J, Yenicesu M, Knights S, Ikizler TA, Schulman G, Hernanz-Schulman M, Shyr Y, Hakim RM. Predictive measures of vascular access thrombosis: a prospective study. Kidney Int. 1997 Dec; 52(6): 1656-62. PMID: 9407514, ISSN: 0085-2538.

Ikizler TA, Schulman G. Adequacy of dialysis. Kidney Int. Suppl. 1997 Nov; 62: S96-100. PMID: 9350693, ISSN: 0098-6577.

Ikizler TA, Himmelfarb J. Nutrition in acute renal failure patients. Adv Ren Replace Ther. 1997 Apr; 4(2 Suppl 1): 54-63. PMID: 9113241, ISSN: 1073-4449.

Ismail N, Ikizler TA. Erythropoietin-induced hypertension. J Med Liban. 1997; 45(1): 25-30. PMID: 9421942, ISSN: 0023-9852.

Ikizler TA, Wingard RL, Sun M, Harvell J, Parker RA, Hakim RM. Increased energy expenditure in hemodialysis patients. J. Am. Soc. Nephrol. 1996 Dec; 7(12): 2646-53. PMID: 8989743, ISSN: 1046-6673.

Ikizler TA, Greene JH, Yenicesu M, Schulman G, Wingard RL, Hakim RM. Nitrogen balance in hospitalized chronic hemodialysis patients. Kidney Int. Suppl. 1996 Dec; 57: S53-6. PMID: 8941922, ISSN: 0098-6577.

Ikizler TA, Hakim RM. Nutrition in end-stage renal disease. Kidney Int. 1996 Aug; 50(2): 343-57. PMID: 8840260, ISSN: 0085-2538.

Ikizler TA, Wingard RL, Flakoll PJ, Schulman G, Parker RA, Hakim RM. Effects of recombinant human growth hormone on plasma and dialysate amino acid profiles in CAPD patients. Kidney Int. 1996 Jul; 50(1): 229-34. PMID: 8807592, ISSN: 0085-2538.

Parker TF, Wingard RL, Husni L, Ikizler TA, Parker RA, Hakim RM. Effect of the membrane biocompatibility on nutritional parameters in chronic hemodialysis patients. Kidney Int. 1996 Feb; 49(2): 551-6. PMID: 8821843, ISSN: 0085-2538.

Ikizler TA, Greene JH, Wingard RL, Parker RA, Hakim RM. Spontaneous dietary protein intake during progression of chronic renal failure. J. Am. Soc. Nephrol. 1995 Nov; 6(5): 1386-91. PMID: 8589313, ISSN: 1046-6673.

Ikizler TA, Wingard RL, Hakim RM. Interventions to treat malnutrition in dialysis patients: the role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone. Am. J. Kidney Dis. 1995 Jul; 26(1): 256-65. PMID: 7611260, PII: 0272-6386(95)90181-7, ISSN: 0272-6386.

Ikizler TA, Wingard RL, Hakim RM. Malnutrition in peritoneal dialysis patients: etiologic factors and treatment options. Perit Dial Int. 1995; 15(5 Suppl): S63-6. PMID: 7578490, ISSN: 0896-8608.

Ikizler TA, Wingard RL, Breyer JA, Schulman G, Parker RA, Hakim RM. Short-term effects of recombinant human growth hormone in CAPD patients. Kidney Int. 1994 Oct; 46(4): 1178-83. PMID: 7861714, ISSN: 0085-2538.

Ikizler TA, Flakoll PJ, Parker RA, Hakim RM. Amino acid and albumin losses during hemodialysis. Kidney Int. 1994 Sep; 46(3): 830-7. PMID: 7996804, ISSN: 0085-2538.

Ikizler, A. Eran, A. Obek. Effects of intravenous amino acid treatment in patients with chronic renal failure. Sisli Etfal Medical Bulletin. 1992; 92/1((Vol.26)): 40-4.