Faculty Appointments
Professor of Medicine
Associate Professor of Health PolicyProfessor of Surgery
Education
M.P.H., Public Health, Vanderbilt University, Nashville, TennesseeM.D., Duke University, Durham, North CarolinaB.S., Emory & Henry College, Emory, Virginia
Office Address
Gastroenterology
1030C MRB IV
TN 2279
1030C MRB IV
TN 2279
Research Keywords
Pharmacoepidemiology
Clinical Research Keywords
Gastroenterology;colon cancer screening; GI hemorrhage; Peptic ulcer disease; NSAIDs; pharmocepidemiology
Publications
Zhao J, Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Jiang M, Kabagambe EK, Zhang B, Hou L, Smalley WE, Edwards TL, Giovannucci EL, Zheng W, Dai Q. Interactions between calcium intake and polymorphisms in genes essential for calcium reabsorption and risk of colorectal neoplasia in a two-phase study. Mol. Carcinog [print-electronic]. 2017 Oct; 56(10): 2258-66. PMID: 28544176, PMCID: PMC5609815, DOI: 10.1002/mc.22678, ISSN: 1098-2744.
Sun P, Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Hou L, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps. J. Nutr. Biochem [print-electronic]. 2017 Sep; 47: 35-40. PMID: 28501704, PMCID: PMC5583031, PII: S0955-2863(16)30708-2, DOI: 10.1016/j.jnutbio.2017.04.016, ISSN: 1873-4847.
Rifkin SB, Shrubsole MJ, Cai Q, Smalley WE, Ness RM, Swift LL, Zheng W, Murff HJ. PUFA levels in erythrocyte membrane phospholipids are differentially associated with colorectal adenoma risk. Br. J. Nutr [print-electronic]. 2017 Jun; 117(11): 1615-22. PMID: 28660850, PII: S0007114517001490, DOI: 10.1017/S0007114517001490, ISSN: 1475-2662.
Su T, Washington MK, Ness RM, Rex DK, Smalley WE, Ulbright TM, Cai Q, Zheng W, Shrubsole MJ. Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee-Indiana Adenoma Recurrence Study. Mol. Carcinog [print-electronic]. 2017 Feb; 56(2): 761-73. PMID: 27479195, PMCID: PMC5541935, DOI: 10.1002/mc.22533, ISSN: 1098-2744.
Ray WA, Chung CP, Murray KT, Smalley WE, Daugherty JR, Dupont WD, Stein CM. Association of Proton Pump Inhibitors With Reduced Risk of Warfarin-Related Serious Upper Gastrointestinal Bleeding. Gastroenterology [print-electronic]. 2016 Dec; 151(6): 1105-1112.e10. PMID: 27639805, PMCID: PMC5124401, PII: S0016-5085(16)35034-X, DOI: 10.1053/j.gastro.2016.08.054, ISSN: 1528-0012.
Davenport JR, Su T, Zhao Z, Coleman HG, Smalley WE, Ness RM, Zheng W, Shrubsole MJ. Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps. Gut [print-electronic]. 2016 Nov 11/15/2016; PMID: 27852795, PMCID: PMC5432410, PII: gutjnl-2016-312893, DOI: 10.1136/gutjnl-2016-312893, ISSN: 1468-3288.
Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Jiang M, Hou L, Kabagambe EK, Zhang B, Smalley WE, Edwards TL, Giovannucci EL, Zheng W, Dai Q. Calcium/magnesium intake ratio, but not magnesium intake, interacts with genetic polymorphism in relation to colorectal neoplasia in a two-phase study. Mol. Carcinog [print-electronic]. 2016 Oct; 55(10): 1449-57. PMID: 26333203, PMCID: PMC4775445, DOI: 10.1002/mc.22387, ISSN: 1098-2744.
Murff HJ, Tindle HA, Shrubsole MJ, Cai Q, Smalley W, Milne GL, Swift LL, Ness RM, Zheng W. Smoking and red blood cell phospholipid membrane fatty acids. Prostaglandins Leukot. Essent. Fatty Acids [print-electronic]. 2016 Sep; 112: 24-31. PMID: 27637337, PMCID: PMC5028119, PII: S0952-3278(16)30119-3, DOI: 10.1016/j.plefa.2016.08.004, ISSN: 1532-2823.
Davenport JR, Cai Q, Ness RM, Milne G, Zhao Z, Smalley WE, Zheng W, Shrubsole MJ. Evaluation of pro-inflammatory markers plasma C-reactive protein and urinary prostaglandin-E2 metabolite in colorectal adenoma risk. Mol. Carcinog [print-electronic]. 2016 Aug; 55(8): 1251-61. PMID: 26333108, PMCID: PMC4816675, DOI: 10.1002/mc.22367, ISSN: 1098-2744.
Tarpley JL, Smalley WE. Making a Difference in Surgery Residency Programs. JAMA Surg. 2016 Feb; 151(2): 119. PMID: 26509411, PII: 2466599, DOI: 10.1001/jamasurg.2015.3653, ISSN: 2168-6262.
Nguyen GC, Smalley WE, Vege SS, Carrasco-Labra A, . American Gastroenterological Association Institute Guideline on the Medical Management of Microscopic Colitis. Gastroenterology [print-electronic]. 2016 Jan; 150(1): 242-6; quiz e17. PMID: 26584605, PII: S0016-5085(15)01625-X, DOI: 10.1053/j.gastro.2015.11.008, ISSN: 1528-0012.
Stollman N, Smalley W, Hirano I, . American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis. Gastroenterology [print-electronic]. 2015 Dec; 149(7): 1944-9. PMID: 26453777, PII: S0016-5085(15)01432-8, DOI: 10.1053/j.gastro.2015.10.003.
Imler TD, Morea J, Kahi C, Cardwell J, Johnson CS, Xu H, Ahnen D, Antaki F, Ashley C, Baffy G, Cho I, Dominitz J, Hou J, Korsten M, Nagar A, Promrat K, Robertson D, Saini S, Shergill A, Smalley W, Imperiale TF. Corrigendum: Multi-Center Colonoscopy Quality Measurement Utilizing Natural Language Processing. Am. J. Gastroenterol. 2015 Dec; 110(12): 1743. PMID: 26673514, PII: ajg2015349, DOI: 10.1038/ajg.2015.349, ISSN: 1572-0241.
Coleman HG, Ness RM, Smalley WE, Zheng W, Shrubsole MJ. Aspects of dietary carbohydrate intake are not related to risk of colorectal polyps in the Tennessee Colorectal Polyp Study. Cancer Causes Control [print-electronic]. 2015 Aug; 26(8): 1197-202. PMID: 26054912, PMCID: PMC4498977, DOI: 10.1007/s10552-015-0605-5, ISSN: 1573-7225.
Coleman HG, Ness RM, Smalley WE, Zheng W, Shrubsole MJ. Aspects of dietary carbohydrate intake are not related to risk of colorectal polyps in the Tennessee Colorectal Polyp Study. Cancer Causes Control [print-electronic]. 2015 Aug; 26(8): 1197-202. PMID: 26054912, PMCID: PMC4498977, DOI: 10.1007/s10552-015-0605-5, ISSN: 1573-7225.
Imler TD, Morea J, Kahi C, Sherer EA, Cardwell J, Johnson CS, Xu H, Ahnen D, Antaki F, Ashley C, Baffy G, Cho I, Dominitz J, Hou J, Korsten M, Nagar A, Promrat K, Robertson D, Saini S, Shergill A, Smalley W, Imperiale TF. Multi-center colonoscopy quality measurement utilizing natural language processing. Am. J. Gastroenterol [print-electronic]. 2015 Apr; 110(4): 543-52. PMID: 25756240, PII: ajg201551, DOI: 10.1038/ajg.2015.51, ISSN: 1572-0241.
Coppola JA, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Ness RM, Fazio S, Zheng W, Murff HJ. Plasma lipid levels and colorectal adenoma risk. Cancer Causes Control [print-electronic]. 2015 Apr; 26(4): 635-43. PMID: 25761410, PMCID: PMC4375726, DOI: 10.1007/s10552-015-0555-y, ISSN: 1573-7225.
Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study. J. Nutr [print-electronic]. 2014 Nov; 144(11): 1734-41. PMID: 25165391, PMCID: PMC4195417, PII: jn.114.196709, DOI: 10.3945/jn.114.196709, ISSN: 1541-6100.
Weinberg DS, Smalley W, Heidelbaugh JJ, Sultan S, . American Gastroenterological Association Institute Guideline on the pharmacological management of irritable bowel syndrome. Gastroenterology [print-electronic]. 2014 Nov; 147(5): 1146-8. PMID: 25224526, PII: S0016-5085(14)01089-0, DOI: 10.1053/j.gastro.2014.09.001.
Fu Z, Shrubsole MJ, Smalley WE, Ness RM, Zheng W. Associations between dietary fiber and colorectal polyp risk differ by polyp type and smoking status. J. Nutr [print-electronic]. 2014 May; 144(5): 592-8. PMID: 24572038, PMCID: PMC4084407, PII: jn.113.183319, DOI: 10.3945/jn.113.183319, ISSN: 1541-6100.
Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Delahanty RH, Murff HJ, Smalley W, Ness RM, Zheng W. Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2013 Jul; 22(7): 1219-26. PMID: 23677573, PMCID: PMC3716448, PII: 1055-9965.EPI-12-1437, DOI: 10.1158/1055-9965.EPI-12-1437, ISSN: 1538-7755.
Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Cai Q, Ness RM, Zheng W. Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps. Carcinogenesis [print-electronic]. 2013 Apr; 34(4): 779-86. PMID: 23299405, PMCID: PMC3616674, PII: bgs410, DOI: 10.1093/carcin/bgs410, ISSN: 1460-2180.
Zhang B, Shrubsole MJ, Li G, Cai Q, Edwards T, Smalley WE, Ness RM, Zheng W. Association of genetic variants for colorectal cancer differs by subtypes of polyps in the colorectum. Carcinogenesis [print-electronic]. 2012 Dec; 33(12): 2417-23. PMID: 23027627, PMCID: PMC3510743, PII: bgs308, DOI: 10.1093/carcin/bgs308, ISSN: 1460-2180.
Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Lifestyle factors and their combined impact on the risk of colorectal polyps. Am. J. Epidemiol [print-electronic]. 2012 Nov 11/1/2012; 176(9): 766-76. PMID: 23079606, PMCID: PMC3571253, PII: kws157, DOI: 10.1093/aje/kws157, ISSN: 1476-6256.
Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Chen Z, Shyr Y, Cai Q, Ness RM, Zheng W. Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps. Am. J. Clin. Nutr [print-electronic]. 2012 Nov; 96(5): 1119-28. PMID: 23015320, PMCID: PMC3471199, PII: ajcn.112.040345, DOI: 10.3945/ajcn.112.040345, ISSN: 1938-3207.
Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Murff HJ, Smalley W, Ness R, Zheng W. A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Jun; 5(6): 855-63. PMID: 22551900, PMCID: PMC3789595, PII: 1940-6207.CAPR-11-0459, DOI: 10.1158/1940-6207.CAPR-11-0459, ISSN: 1940-6215.
Murff HJ, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Milne GL, Ness RM, Zheng W. Dietary intake of PUFAs and colorectal polyp risk. Am. J. Clin. Nutr [print-electronic]. 2012 Mar; 95(3): 703-12. PMID: 22277551, PMCID: PMC3278245, PII: ajcn.111.024000, DOI: 10.3945/ajcn.111.024000, ISSN: 1938-3207.
Shrubsole MJ, Cai Q, Wen W, Milne G, Smalley WE, Chen Z, Ness RM, Zheng W. Urinary prostaglandin E2 metabolite and risk for colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Feb; 5(2): 336-42. PMID: 22166248, PMCID: PMC3273609, PII: 1940-6207.CAPR-11-0426, DOI: 10.1158/1940-6207.CAPR-11-0426, ISSN: 1940-6215.
Murff HJ, Shrubsole MJ, Chen Z, Smalley WE, Chen H, Shyr Y, Ness RM, Zheng W. Nonsteroidal anti-inflammatory drug use and risk of adenomatous and hyperplastic polyps. Cancer Prev Res (Phila) [print-electronic]. 2011 Nov; 4(11): 1799-807. PMID: 21764857, PMCID: PMC3203989, PII: 1940-6207.CAPR-11-0107, DOI: 10.1158/1940-6207.CAPR-11-0107, ISSN: 1940-6215.
Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. Cancer Prev Res (Phila) [print-electronic]. 2011 Oct; 4(10): 1686-97. PMID: 21803984, PMCID: PMC3188364, PII: 1940-6207.CAPR-11-0191, DOI: 10.1158/1940-6207.CAPR-11-0191, ISSN: 1940-6215.
Cunningham A, Stein CM, Chung CP, Daugherty JR, Smalley WE, Ray WA. An automated database case definition for serious bleeding related to oral anticoagulant use. Pharmacoepidemiol Drug Saf [print-electronic]. 2011 Jun; 20(6): 560-6. PMID: 21387461, PMCID: PMC3365595, DOI: 10.1002/pds.2109, ISSN: 1099-1557.
Smalley W. Administrative data and measurement of colonoscopy quality: not ready for prime time? [editorial]. Gastrointest. Endosc. 2011 Mar; 73(3): 454-5. PMID: 21353842, PII: S0016-5107(10)02404-1, DOI: 10.1016/j.gie.2010.11.042, ISSN: 1097-6779.
Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, Daugherty JR, Kaltenbach LA, Stein CM. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann. Intern. Med. 2010 Mar 3/16/2010; 152(6): 337-45. PMID: 20231564, PMCID: PMC3176584, PII: 152/6/337, DOI: 10.7326/0003-4819-152-6-201003160-00003, ISSN: 1539-3704.
Wu H, Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Smalley WE, Chen H, Li M, Shyr Y, Zheng W. Fruit and vegetable intakes are associated with lower risk of colorectal adenomas. J. Nutr [print-electronic]. 2009 Feb; 139(2): 340-4. PMID: 19091801, PMCID: PMC2646202, PII: jn.108.098889, DOI: 10.3945/jn.108.098889, ISSN: 1541-6100.
Shrubsole MJ, Wu H, Ness RM, Shyr Y, Smalley WE, Zheng W. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am. J. Epidemiol [print-electronic]. 2008 May 5/1/2008; 167(9): 1050-8. PMID: 18304959, PII: kwm400, DOI: 10.1093/aje/kwm400, ISSN: 1476-6256.
Shin A, Shrubsole MJ, Rice JM, Cai Q, Doll MA, Long J, Smalley WE, Shyr Y, Sinha R, Ness RM, Hein DW, Zheng W. Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol. Biomarkers Prev. 2008 Feb; 17(2): 320-9. PMID: 18268115, PMCID: PMC2572782, PII: 17/2/320, DOI: 10.1158/1055-9965.EPI-07-0615, ISSN: 1055-9965.
Abraham NS, Hartman C, Castillo D, Richardson P, Smalley W. Effectiveness of national provider prescription of PPI gastroprotection among elderly NSAID users. Am. J. Gastroenterol. 2008 Feb; 103(2): 323-32. PMID: 18289200, PII: AJG1595, DOI: 10.1111/j.1572-0241.2007.01595.x, ISSN: 0002-9270.
Ray WA, Chung CP, Stein CM, Smalley WE, Hall K, Arbogast PG, Griffin MR. Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Gastroenterology [print-electronic]. 2007 Sep; 133(3): 790-8. PMID: 17854591, PII: S0016-5085(07)01290-5, DOI: 10.1053/j.gastro.2007.06.058, ISSN: 0016-5085.
Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am. J. Clin. Nutr. 2007 Sep; 86(3): 743-51. PMID: 17823441, PMCID: PMC2082111, PII: 86/3/743, ISSN: 0002-9165.
Davila JA, Weston A, Smalley W, El-Serag HB. Utilization of screening for hepatocellular carcinoma in the United States. J. Clin. Gastroenterol. 2007 Sep; 41(8): 777-82. PMID: 17700427, PII: 00004836-200709000-00009, DOI: 10.1097/MCG.0b013e3180381560, ISSN: 0192-0790.
Shin A, Shrubsole MJ, Ness RM, Wu H, Sinha R, Smalley WE, Shyr Y, Zheng W. Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp Study. Int. J. Cancer. 2007 Jul 7/1/2007; 121(1): 136-42. PMID: 17354224, DOI: 10.1002/ijc.22664, ISSN: 0020-7136.
Hawkey CJ, Weinstein WM, Smalley W, Gitton X, Sallstig P, Stricker K, Krammer G, Mellein B, Richard D, Matchaba P. Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study. Gastroenterology [print-electronic]. 2007 Jul; 133(1): 57-64. PMID: 17631131, PII: S0016-5085(07)00831-1, DOI: 10.1053/j.gastro.2007.04.045, ISSN: 0016-5085.
Wall RJ, Shyr Y, Smalley W. Nonsteroidal anti-inflammatory drugs and lung cancer risk: a population-based case control study. J Thorac Oncol. 2007 Feb; 2(2): 109-14. PMID: 17410024, PII: 01243894-200702000-00003, DOI: /JTO.0b013e31802f1cc5, ISSN: 1556-1380.
Murff HJ, Shrubsole MJ, Smalley WE, Wu H, Shyr Y, Ness RM, Zheng W. The interaction of age and hormone replacement therapy on colon adenoma risk. Cancer Detect. Prev [print-electronic]. 2007; 31(2): 161-5. PMID: 17433566, PMCID: PMC1949417, PII: S0361-090X(07)00034-7, DOI: 10.1016/j.cdp.2007.03.002, ISSN: 0361-090X.
Ye C, Shrubsole MJ, Cai Q, Ness R, Grady WM, Smalley W, Cai H, Washington K, Zheng W. Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. Oncol. Rep. 2006 Aug; 16(2): 429-35. PMID: 16820927, ISSN: 1021-335X.
Schrager JJ, Tarpley JL, Smalley WE, Austin MT, Pearson AS. Endoscopic ultrasound: impact on survival in patients with esophageal cancer. Am. J. Surg. 2005 Nov; 190(5): 682-6. PMID: 16226939, PII: S0002-9610(05)00629-X, DOI: 10.1016/j.amjsurg.2005.07.002, ISSN: 0002-9610.
Abraham NS, El-Serag HB, Johnson ML, Hartman C, Richardson P, Ray WA, Smalley W. National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs. Gastroenterology. 2005 Oct; 129(4): 1171-8. PMID: 16230071, PII: S0016-5085(05)01578-7, DOI: 10.1053/j.gastro.2005.08.003, ISSN: 0016-5085.
Poulose BK, Holzman MD, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Griffin MR. National variations in morbid obesity and bariatric surgery use. J. Am. Coll. Surg. 2005 Jul; 201(1): 77-84. PMID: 15978447, PII: S1072-7515(05)00337-6, DOI: 10.1016/j.jamcollsurg.2005.03.022, ISSN: 1072-7515.
Poulose BK, Griffin MR, Moore DE, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Holzman MD. Risk factors for post-operative mortality in bariatric surgery. J. Surg. Res. 2005 Jul 7/1/2005; 127(1): 1-7. PMID: 15964300, PII: S0022-4804(04)00731-0, DOI: 10.1016/j.jss.2004.12.017, ISSN: 0022-4804.
Poulose BK, Griffin MR, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Holzman MD. National analysis of adverse patient safety for events in bariatric surgery. Am Surg. 2005 May; 71(5): 406-13. PMID: 15986971, ISSN: 0003-1348.
Petko Z, Ghiassi M, Shuber A, Gorham J, Smalley W, Washington MK, Schultenover S, Gautam S, Markowitz SD, Grady WM. Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin. Cancer Res. 2005 Feb 2/1/2005; 11(3): 1203-9. PMID: 15709190, PII: 11/3/1203, ISSN: 1078-0432.
Rogers SO, Ray WA, Smalley WE. A population-based study of survival among elderly persons diagnosed with colorectal cancer: does race matter if all are insured? (United States). Cancer Causes Control. 2004 Mar; 15(2): 193-9. PMID: 15017132, PII: 5264940, DOI: 10.1023/B:CACO.0000019511.67989.09, ISSN: 0957-5243.
Khaitan L, Ray WA, Holzman MD, Smalley WE. Health care utilization after medical and surgical therapy for gastroesophageal reflux disease: a population-based study, 1996 to 2000. Arch Surg. 2003 Dec; 138(12): 1356-61. PMID: 14662539, PII: 138/12/1356, DOI: 10.1001/archsurg.138.12.1356, ISSN: 0004-0010.
Smalley W, Stein CM, Arbogast PG, Eisen G, Ray WA, Griffin M. Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. Arthritis Rheum. 2002 Aug; 46(8): 2195-200. PMID: 12209525, DOI: 10.1002/art.10425, ISSN: 0004-3591.
Smalley W. Drug safety: can simple interventions be effective in a complex world? [editorial]. Pharmacoepidemiol Drug Saf. 2001 May; 10(3): 209-10. PMID: 11501333, DOI: 10.1002/pds.593, ISSN: 1053-8569.
Kandil HM, Tanner G, Smalley W, Halter S, Radhika A, Dubois RN. Cyclooxygenase-2 expression in Barrett's esophagus. Dig. Dis. Sci. 2001 Apr; 46(4): 785-9. PMID: 11330414, ISSN: 0163-2116.
Holzman MD, Mitchel EF, Ray WA, Smalley WE. Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: a population-based study. J. Am. Coll. Surg. 2001 Jan; 192(1): 17-24. PMID: 11192919, PII: S1072-7515(00)00746-8, ISSN: 1072-7515.
Smalley W, Shatin D, Wysowski DK, Gurwitz J, Andrade SE, Goodman M, Chan KA, Platt R, Schech SD, Ray WA. Contraindicated use of cisapride: impact of food and drug administration regulatory action. JAMA. 2000 Dec 12/20/2000; 284(23): 3036-9. PMID: 11122591, PII: joc00932, ISSN: 0098-7484.
Smalley WE, Eisen GM. Colorectal cancer screening 2000: the role of colonoscopy in average-risk individuals. Curr Gastroenterol Rep. 2000 Oct; 2(5): 406-12. PMID: 10998669, ISSN: 1522-8037.
Smalley W, Ray WA, Daugherty J, Griffin MR. Use of nonsteroidal anti-inflammatory drugs and incidence of colorectal cancer: a population-based study. Arch. Intern. Med. 1999 Jan 1/25/1999; 159(2): 161-6. PMID: 9927099, ISSN: 0003-9926.
Smalley WE, Ray WA, Daugherty JR, Griffin MR. No association between calcium channel blocker use and confirmed bleeding peptic ulcer disease. Am. J. Epidemiol. 1998 Aug 8/15/1998; 148(4): 350-4. PMID: 9717878, ISSN: 0002-9262.
Williams CS, Smalley W, DuBois RN. Aspirin use and potential mechanisms for colorectal cancer prevention. J. Clin. Invest. 1997 Sep 9/15/1997; 100(6): 1325-9. PMID: 9294096, PMCID: PMC508309, DOI: 10.1172/JCI119651, ISSN: 0021-9738.
Smalley WE, DuBois RN. Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv. Pharmacol. 1997; 39: 1-20. PMID: 9160111, ISSN: 1054-3589.
DuBois RN, Smalley WE. Cyclooxygenase, NSAIDs, and colorectal cancer. J. Gastroenterol. 1996 Dec; 31(6): 898-906. PMID: 9027660, ISSN: 0944-1174.
DuBois RN, Giardiello FM, Smalley WE. Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol. Clin. North Am. 1996 Dec; 25(4): 773-91. PMID: 8960892, ISSN: 0889-8553.
Smalley WE, Griffin MR, Fought RL, Ray WA. Excess costs from gastrointestinal disease associated with nonsteroidal anti-inflammatory drugs. J Gen Intern Med. 1996 Aug; 11(8): 461-9. PMID: 8872783, ISSN: 0884-8734.
Smalley WE, Griffin MR. The risks and costs of upper gastrointestinal disease attributable to NSAIDs. Gastroenterol. Clin. North Am. 1996 Jun; 25(2): 373-96. PMID: 9229579, ISSN: 0889-8553.
Smalley WE, Griffin MR, Fought RL, Sullivan L, Ray WA. Effect of a prior-authorization requirement on the use of nonsteroidal antiinflammatory drugs by Medicaid patients. N. Engl. J. Med. 1995 Jun 6/15/1995; 332(24): 1612-7. PMID: 7753141, DOI: 10.1056/NEJM199506153322406, ISSN: 0028-4793.
Smalley WE, Ray WA, Daugherty JR, Griffin MR. Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons. Am. J. Epidemiol. 1995 Mar 3/15/1995; 141(6): 539-45. PMID: 7900721, ISSN: 0002-9262.
Griffin MR, Smalley WE. Drugs and ulcers: clues about mucosal protection from epidemiologic studies. J. Clin. Gastroenterol. 1995; 21 Suppl 1: S113-9. PMID: 8775002, ISSN: 0192-0790.
Prazma J, Smalley WE, Covington S, Pillsbury HC. Cochlear blood flow. The effect of six hours of noise exposure. Arch. Otolaryngol. Head Neck Surg. 1988 Jun; 114(6): 657-60. PMID: 3365338, ISSN: 0886-4470.
Valenzuela GA, Smalley WE, Schain DC, Vance ML, McCallum RW. Reversibility of gastric dysmotility in cortisol deficiency. Am. J. Gastroenterol. 1987 Oct; 82(10): 1066-8. PMID: 2821798, ISSN: 0002-9270.
Sun P, Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Hou L, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps. J. Nutr. Biochem [print-electronic]. 2017 Sep; 47: 35-40. PMID: 28501704, PMCID: PMC5583031, PII: S0955-2863(16)30708-2, DOI: 10.1016/j.jnutbio.2017.04.016, ISSN: 1873-4847.
Rifkin SB, Shrubsole MJ, Cai Q, Smalley WE, Ness RM, Swift LL, Zheng W, Murff HJ. PUFA levels in erythrocyte membrane phospholipids are differentially associated with colorectal adenoma risk. Br. J. Nutr [print-electronic]. 2017 Jun; 117(11): 1615-22. PMID: 28660850, PII: S0007114517001490, DOI: 10.1017/S0007114517001490, ISSN: 1475-2662.
Su T, Washington MK, Ness RM, Rex DK, Smalley WE, Ulbright TM, Cai Q, Zheng W, Shrubsole MJ. Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee-Indiana Adenoma Recurrence Study. Mol. Carcinog [print-electronic]. 2017 Feb; 56(2): 761-73. PMID: 27479195, PMCID: PMC5541935, DOI: 10.1002/mc.22533, ISSN: 1098-2744.
Ray WA, Chung CP, Murray KT, Smalley WE, Daugherty JR, Dupont WD, Stein CM. Association of Proton Pump Inhibitors With Reduced Risk of Warfarin-Related Serious Upper Gastrointestinal Bleeding. Gastroenterology [print-electronic]. 2016 Dec; 151(6): 1105-1112.e10. PMID: 27639805, PMCID: PMC5124401, PII: S0016-5085(16)35034-X, DOI: 10.1053/j.gastro.2016.08.054, ISSN: 1528-0012.
Davenport JR, Su T, Zhao Z, Coleman HG, Smalley WE, Ness RM, Zheng W, Shrubsole MJ. Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps. Gut [print-electronic]. 2016 Nov 11/15/2016; PMID: 27852795, PMCID: PMC5432410, PII: gutjnl-2016-312893, DOI: 10.1136/gutjnl-2016-312893, ISSN: 1468-3288.
Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Jiang M, Hou L, Kabagambe EK, Zhang B, Smalley WE, Edwards TL, Giovannucci EL, Zheng W, Dai Q. Calcium/magnesium intake ratio, but not magnesium intake, interacts with genetic polymorphism in relation to colorectal neoplasia in a two-phase study. Mol. Carcinog [print-electronic]. 2016 Oct; 55(10): 1449-57. PMID: 26333203, PMCID: PMC4775445, DOI: 10.1002/mc.22387, ISSN: 1098-2744.
Murff HJ, Tindle HA, Shrubsole MJ, Cai Q, Smalley W, Milne GL, Swift LL, Ness RM, Zheng W. Smoking and red blood cell phospholipid membrane fatty acids. Prostaglandins Leukot. Essent. Fatty Acids [print-electronic]. 2016 Sep; 112: 24-31. PMID: 27637337, PMCID: PMC5028119, PII: S0952-3278(16)30119-3, DOI: 10.1016/j.plefa.2016.08.004, ISSN: 1532-2823.
Davenport JR, Cai Q, Ness RM, Milne G, Zhao Z, Smalley WE, Zheng W, Shrubsole MJ. Evaluation of pro-inflammatory markers plasma C-reactive protein and urinary prostaglandin-E2 metabolite in colorectal adenoma risk. Mol. Carcinog [print-electronic]. 2016 Aug; 55(8): 1251-61. PMID: 26333108, PMCID: PMC4816675, DOI: 10.1002/mc.22367, ISSN: 1098-2744.
Tarpley JL, Smalley WE. Making a Difference in Surgery Residency Programs. JAMA Surg. 2016 Feb; 151(2): 119. PMID: 26509411, PII: 2466599, DOI: 10.1001/jamasurg.2015.3653, ISSN: 2168-6262.
Nguyen GC, Smalley WE, Vege SS, Carrasco-Labra A, . American Gastroenterological Association Institute Guideline on the Medical Management of Microscopic Colitis. Gastroenterology [print-electronic]. 2016 Jan; 150(1): 242-6; quiz e17. PMID: 26584605, PII: S0016-5085(15)01625-X, DOI: 10.1053/j.gastro.2015.11.008, ISSN: 1528-0012.
Stollman N, Smalley W, Hirano I, . American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis. Gastroenterology [print-electronic]. 2015 Dec; 149(7): 1944-9. PMID: 26453777, PII: S0016-5085(15)01432-8, DOI: 10.1053/j.gastro.2015.10.003.
Imler TD, Morea J, Kahi C, Cardwell J, Johnson CS, Xu H, Ahnen D, Antaki F, Ashley C, Baffy G, Cho I, Dominitz J, Hou J, Korsten M, Nagar A, Promrat K, Robertson D, Saini S, Shergill A, Smalley W, Imperiale TF. Corrigendum: Multi-Center Colonoscopy Quality Measurement Utilizing Natural Language Processing. Am. J. Gastroenterol. 2015 Dec; 110(12): 1743. PMID: 26673514, PII: ajg2015349, DOI: 10.1038/ajg.2015.349, ISSN: 1572-0241.
Coleman HG, Ness RM, Smalley WE, Zheng W, Shrubsole MJ. Aspects of dietary carbohydrate intake are not related to risk of colorectal polyps in the Tennessee Colorectal Polyp Study. Cancer Causes Control [print-electronic]. 2015 Aug; 26(8): 1197-202. PMID: 26054912, PMCID: PMC4498977, DOI: 10.1007/s10552-015-0605-5, ISSN: 1573-7225.
Coleman HG, Ness RM, Smalley WE, Zheng W, Shrubsole MJ. Aspects of dietary carbohydrate intake are not related to risk of colorectal polyps in the Tennessee Colorectal Polyp Study. Cancer Causes Control [print-electronic]. 2015 Aug; 26(8): 1197-202. PMID: 26054912, PMCID: PMC4498977, DOI: 10.1007/s10552-015-0605-5, ISSN: 1573-7225.
Imler TD, Morea J, Kahi C, Sherer EA, Cardwell J, Johnson CS, Xu H, Ahnen D, Antaki F, Ashley C, Baffy G, Cho I, Dominitz J, Hou J, Korsten M, Nagar A, Promrat K, Robertson D, Saini S, Shergill A, Smalley W, Imperiale TF. Multi-center colonoscopy quality measurement utilizing natural language processing. Am. J. Gastroenterol [print-electronic]. 2015 Apr; 110(4): 543-52. PMID: 25756240, PII: ajg201551, DOI: 10.1038/ajg.2015.51, ISSN: 1572-0241.
Coppola JA, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Ness RM, Fazio S, Zheng W, Murff HJ. Plasma lipid levels and colorectal adenoma risk. Cancer Causes Control [print-electronic]. 2015 Apr; 26(4): 635-43. PMID: 25761410, PMCID: PMC4375726, DOI: 10.1007/s10552-015-0555-y, ISSN: 1573-7225.
Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study. J. Nutr [print-electronic]. 2014 Nov; 144(11): 1734-41. PMID: 25165391, PMCID: PMC4195417, PII: jn.114.196709, DOI: 10.3945/jn.114.196709, ISSN: 1541-6100.
Weinberg DS, Smalley W, Heidelbaugh JJ, Sultan S, . American Gastroenterological Association Institute Guideline on the pharmacological management of irritable bowel syndrome. Gastroenterology [print-electronic]. 2014 Nov; 147(5): 1146-8. PMID: 25224526, PII: S0016-5085(14)01089-0, DOI: 10.1053/j.gastro.2014.09.001.
Fu Z, Shrubsole MJ, Smalley WE, Ness RM, Zheng W. Associations between dietary fiber and colorectal polyp risk differ by polyp type and smoking status. J. Nutr [print-electronic]. 2014 May; 144(5): 592-8. PMID: 24572038, PMCID: PMC4084407, PII: jn.113.183319, DOI: 10.3945/jn.113.183319, ISSN: 1541-6100.
Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Delahanty RH, Murff HJ, Smalley W, Ness RM, Zheng W. Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2013 Jul; 22(7): 1219-26. PMID: 23677573, PMCID: PMC3716448, PII: 1055-9965.EPI-12-1437, DOI: 10.1158/1055-9965.EPI-12-1437, ISSN: 1538-7755.
Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Cai Q, Ness RM, Zheng W. Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps. Carcinogenesis [print-electronic]. 2013 Apr; 34(4): 779-86. PMID: 23299405, PMCID: PMC3616674, PII: bgs410, DOI: 10.1093/carcin/bgs410, ISSN: 1460-2180.
Zhang B, Shrubsole MJ, Li G, Cai Q, Edwards T, Smalley WE, Ness RM, Zheng W. Association of genetic variants for colorectal cancer differs by subtypes of polyps in the colorectum. Carcinogenesis [print-electronic]. 2012 Dec; 33(12): 2417-23. PMID: 23027627, PMCID: PMC3510743, PII: bgs308, DOI: 10.1093/carcin/bgs308, ISSN: 1460-2180.
Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Lifestyle factors and their combined impact on the risk of colorectal polyps. Am. J. Epidemiol [print-electronic]. 2012 Nov 11/1/2012; 176(9): 766-76. PMID: 23079606, PMCID: PMC3571253, PII: kws157, DOI: 10.1093/aje/kws157, ISSN: 1476-6256.
Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Chen Z, Shyr Y, Cai Q, Ness RM, Zheng W. Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps. Am. J. Clin. Nutr [print-electronic]. 2012 Nov; 96(5): 1119-28. PMID: 23015320, PMCID: PMC3471199, PII: ajcn.112.040345, DOI: 10.3945/ajcn.112.040345, ISSN: 1938-3207.
Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Murff HJ, Smalley W, Ness R, Zheng W. A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Jun; 5(6): 855-63. PMID: 22551900, PMCID: PMC3789595, PII: 1940-6207.CAPR-11-0459, DOI: 10.1158/1940-6207.CAPR-11-0459, ISSN: 1940-6215.
Murff HJ, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Milne GL, Ness RM, Zheng W. Dietary intake of PUFAs and colorectal polyp risk. Am. J. Clin. Nutr [print-electronic]. 2012 Mar; 95(3): 703-12. PMID: 22277551, PMCID: PMC3278245, PII: ajcn.111.024000, DOI: 10.3945/ajcn.111.024000, ISSN: 1938-3207.
Shrubsole MJ, Cai Q, Wen W, Milne G, Smalley WE, Chen Z, Ness RM, Zheng W. Urinary prostaglandin E2 metabolite and risk for colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Feb; 5(2): 336-42. PMID: 22166248, PMCID: PMC3273609, PII: 1940-6207.CAPR-11-0426, DOI: 10.1158/1940-6207.CAPR-11-0426, ISSN: 1940-6215.
Murff HJ, Shrubsole MJ, Chen Z, Smalley WE, Chen H, Shyr Y, Ness RM, Zheng W. Nonsteroidal anti-inflammatory drug use and risk of adenomatous and hyperplastic polyps. Cancer Prev Res (Phila) [print-electronic]. 2011 Nov; 4(11): 1799-807. PMID: 21764857, PMCID: PMC3203989, PII: 1940-6207.CAPR-11-0107, DOI: 10.1158/1940-6207.CAPR-11-0107, ISSN: 1940-6215.
Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. Cancer Prev Res (Phila) [print-electronic]. 2011 Oct; 4(10): 1686-97. PMID: 21803984, PMCID: PMC3188364, PII: 1940-6207.CAPR-11-0191, DOI: 10.1158/1940-6207.CAPR-11-0191, ISSN: 1940-6215.
Cunningham A, Stein CM, Chung CP, Daugherty JR, Smalley WE, Ray WA. An automated database case definition for serious bleeding related to oral anticoagulant use. Pharmacoepidemiol Drug Saf [print-electronic]. 2011 Jun; 20(6): 560-6. PMID: 21387461, PMCID: PMC3365595, DOI: 10.1002/pds.2109, ISSN: 1099-1557.
Smalley W. Administrative data and measurement of colonoscopy quality: not ready for prime time? [editorial]. Gastrointest. Endosc. 2011 Mar; 73(3): 454-5. PMID: 21353842, PII: S0016-5107(10)02404-1, DOI: 10.1016/j.gie.2010.11.042, ISSN: 1097-6779.
Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, Daugherty JR, Kaltenbach LA, Stein CM. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann. Intern. Med. 2010 Mar 3/16/2010; 152(6): 337-45. PMID: 20231564, PMCID: PMC3176584, PII: 152/6/337, DOI: 10.7326/0003-4819-152-6-201003160-00003, ISSN: 1539-3704.
Wu H, Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Smalley WE, Chen H, Li M, Shyr Y, Zheng W. Fruit and vegetable intakes are associated with lower risk of colorectal adenomas. J. Nutr [print-electronic]. 2009 Feb; 139(2): 340-4. PMID: 19091801, PMCID: PMC2646202, PII: jn.108.098889, DOI: 10.3945/jn.108.098889, ISSN: 1541-6100.
Shrubsole MJ, Wu H, Ness RM, Shyr Y, Smalley WE, Zheng W. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am. J. Epidemiol [print-electronic]. 2008 May 5/1/2008; 167(9): 1050-8. PMID: 18304959, PII: kwm400, DOI: 10.1093/aje/kwm400, ISSN: 1476-6256.
Shin A, Shrubsole MJ, Rice JM, Cai Q, Doll MA, Long J, Smalley WE, Shyr Y, Sinha R, Ness RM, Hein DW, Zheng W. Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol. Biomarkers Prev. 2008 Feb; 17(2): 320-9. PMID: 18268115, PMCID: PMC2572782, PII: 17/2/320, DOI: 10.1158/1055-9965.EPI-07-0615, ISSN: 1055-9965.
Abraham NS, Hartman C, Castillo D, Richardson P, Smalley W. Effectiveness of national provider prescription of PPI gastroprotection among elderly NSAID users. Am. J. Gastroenterol. 2008 Feb; 103(2): 323-32. PMID: 18289200, PII: AJG1595, DOI: 10.1111/j.1572-0241.2007.01595.x, ISSN: 0002-9270.
Ray WA, Chung CP, Stein CM, Smalley WE, Hall K, Arbogast PG, Griffin MR. Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Gastroenterology [print-electronic]. 2007 Sep; 133(3): 790-8. PMID: 17854591, PII: S0016-5085(07)01290-5, DOI: 10.1053/j.gastro.2007.06.058, ISSN: 0016-5085.
Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am. J. Clin. Nutr. 2007 Sep; 86(3): 743-51. PMID: 17823441, PMCID: PMC2082111, PII: 86/3/743, ISSN: 0002-9165.
Davila JA, Weston A, Smalley W, El-Serag HB. Utilization of screening for hepatocellular carcinoma in the United States. J. Clin. Gastroenterol. 2007 Sep; 41(8): 777-82. PMID: 17700427, PII: 00004836-200709000-00009, DOI: 10.1097/MCG.0b013e3180381560, ISSN: 0192-0790.
Shin A, Shrubsole MJ, Ness RM, Wu H, Sinha R, Smalley WE, Shyr Y, Zheng W. Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp Study. Int. J. Cancer. 2007 Jul 7/1/2007; 121(1): 136-42. PMID: 17354224, DOI: 10.1002/ijc.22664, ISSN: 0020-7136.
Hawkey CJ, Weinstein WM, Smalley W, Gitton X, Sallstig P, Stricker K, Krammer G, Mellein B, Richard D, Matchaba P. Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study. Gastroenterology [print-electronic]. 2007 Jul; 133(1): 57-64. PMID: 17631131, PII: S0016-5085(07)00831-1, DOI: 10.1053/j.gastro.2007.04.045, ISSN: 0016-5085.
Wall RJ, Shyr Y, Smalley W. Nonsteroidal anti-inflammatory drugs and lung cancer risk: a population-based case control study. J Thorac Oncol. 2007 Feb; 2(2): 109-14. PMID: 17410024, PII: 01243894-200702000-00003, DOI: /JTO.0b013e31802f1cc5, ISSN: 1556-1380.
Murff HJ, Shrubsole MJ, Smalley WE, Wu H, Shyr Y, Ness RM, Zheng W. The interaction of age and hormone replacement therapy on colon adenoma risk. Cancer Detect. Prev [print-electronic]. 2007; 31(2): 161-5. PMID: 17433566, PMCID: PMC1949417, PII: S0361-090X(07)00034-7, DOI: 10.1016/j.cdp.2007.03.002, ISSN: 0361-090X.
Ye C, Shrubsole MJ, Cai Q, Ness R, Grady WM, Smalley W, Cai H, Washington K, Zheng W. Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. Oncol. Rep. 2006 Aug; 16(2): 429-35. PMID: 16820927, ISSN: 1021-335X.
Schrager JJ, Tarpley JL, Smalley WE, Austin MT, Pearson AS. Endoscopic ultrasound: impact on survival in patients with esophageal cancer. Am. J. Surg. 2005 Nov; 190(5): 682-6. PMID: 16226939, PII: S0002-9610(05)00629-X, DOI: 10.1016/j.amjsurg.2005.07.002, ISSN: 0002-9610.
Abraham NS, El-Serag HB, Johnson ML, Hartman C, Richardson P, Ray WA, Smalley W. National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs. Gastroenterology. 2005 Oct; 129(4): 1171-8. PMID: 16230071, PII: S0016-5085(05)01578-7, DOI: 10.1053/j.gastro.2005.08.003, ISSN: 0016-5085.
Poulose BK, Holzman MD, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Griffin MR. National variations in morbid obesity and bariatric surgery use. J. Am. Coll. Surg. 2005 Jul; 201(1): 77-84. PMID: 15978447, PII: S1072-7515(05)00337-6, DOI: 10.1016/j.jamcollsurg.2005.03.022, ISSN: 1072-7515.
Poulose BK, Griffin MR, Moore DE, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Holzman MD. Risk factors for post-operative mortality in bariatric surgery. J. Surg. Res. 2005 Jul 7/1/2005; 127(1): 1-7. PMID: 15964300, PII: S0022-4804(04)00731-0, DOI: 10.1016/j.jss.2004.12.017, ISSN: 0022-4804.
Poulose BK, Griffin MR, Zhu Y, Smalley W, Richards WO, Wright JK, Melvin W, Holzman MD. National analysis of adverse patient safety for events in bariatric surgery. Am Surg. 2005 May; 71(5): 406-13. PMID: 15986971, ISSN: 0003-1348.
Petko Z, Ghiassi M, Shuber A, Gorham J, Smalley W, Washington MK, Schultenover S, Gautam S, Markowitz SD, Grady WM. Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin. Cancer Res. 2005 Feb 2/1/2005; 11(3): 1203-9. PMID: 15709190, PII: 11/3/1203, ISSN: 1078-0432.
Rogers SO, Ray WA, Smalley WE. A population-based study of survival among elderly persons diagnosed with colorectal cancer: does race matter if all are insured? (United States). Cancer Causes Control. 2004 Mar; 15(2): 193-9. PMID: 15017132, PII: 5264940, DOI: 10.1023/B:CACO.0000019511.67989.09, ISSN: 0957-5243.
Khaitan L, Ray WA, Holzman MD, Smalley WE. Health care utilization after medical and surgical therapy for gastroesophageal reflux disease: a population-based study, 1996 to 2000. Arch Surg. 2003 Dec; 138(12): 1356-61. PMID: 14662539, PII: 138/12/1356, DOI: 10.1001/archsurg.138.12.1356, ISSN: 0004-0010.
Smalley W, Stein CM, Arbogast PG, Eisen G, Ray WA, Griffin M. Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. Arthritis Rheum. 2002 Aug; 46(8): 2195-200. PMID: 12209525, DOI: 10.1002/art.10425, ISSN: 0004-3591.
Smalley W. Drug safety: can simple interventions be effective in a complex world? [editorial]. Pharmacoepidemiol Drug Saf. 2001 May; 10(3): 209-10. PMID: 11501333, DOI: 10.1002/pds.593, ISSN: 1053-8569.
Kandil HM, Tanner G, Smalley W, Halter S, Radhika A, Dubois RN. Cyclooxygenase-2 expression in Barrett's esophagus. Dig. Dis. Sci. 2001 Apr; 46(4): 785-9. PMID: 11330414, ISSN: 0163-2116.
Holzman MD, Mitchel EF, Ray WA, Smalley WE. Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: a population-based study. J. Am. Coll. Surg. 2001 Jan; 192(1): 17-24. PMID: 11192919, PII: S1072-7515(00)00746-8, ISSN: 1072-7515.
Smalley W, Shatin D, Wysowski DK, Gurwitz J, Andrade SE, Goodman M, Chan KA, Platt R, Schech SD, Ray WA. Contraindicated use of cisapride: impact of food and drug administration regulatory action. JAMA. 2000 Dec 12/20/2000; 284(23): 3036-9. PMID: 11122591, PII: joc00932, ISSN: 0098-7484.
Smalley WE, Eisen GM. Colorectal cancer screening 2000: the role of colonoscopy in average-risk individuals. Curr Gastroenterol Rep. 2000 Oct; 2(5): 406-12. PMID: 10998669, ISSN: 1522-8037.
Smalley W, Ray WA, Daugherty J, Griffin MR. Use of nonsteroidal anti-inflammatory drugs and incidence of colorectal cancer: a population-based study. Arch. Intern. Med. 1999 Jan 1/25/1999; 159(2): 161-6. PMID: 9927099, ISSN: 0003-9926.
Smalley WE, Ray WA, Daugherty JR, Griffin MR. No association between calcium channel blocker use and confirmed bleeding peptic ulcer disease. Am. J. Epidemiol. 1998 Aug 8/15/1998; 148(4): 350-4. PMID: 9717878, ISSN: 0002-9262.
Williams CS, Smalley W, DuBois RN. Aspirin use and potential mechanisms for colorectal cancer prevention. J. Clin. Invest. 1997 Sep 9/15/1997; 100(6): 1325-9. PMID: 9294096, PMCID: PMC508309, DOI: 10.1172/JCI119651, ISSN: 0021-9738.
Smalley WE, DuBois RN. Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv. Pharmacol. 1997; 39: 1-20. PMID: 9160111, ISSN: 1054-3589.
DuBois RN, Smalley WE. Cyclooxygenase, NSAIDs, and colorectal cancer. J. Gastroenterol. 1996 Dec; 31(6): 898-906. PMID: 9027660, ISSN: 0944-1174.
DuBois RN, Giardiello FM, Smalley WE. Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol. Clin. North Am. 1996 Dec; 25(4): 773-91. PMID: 8960892, ISSN: 0889-8553.
Smalley WE, Griffin MR, Fought RL, Ray WA. Excess costs from gastrointestinal disease associated with nonsteroidal anti-inflammatory drugs. J Gen Intern Med. 1996 Aug; 11(8): 461-9. PMID: 8872783, ISSN: 0884-8734.
Smalley WE, Griffin MR. The risks and costs of upper gastrointestinal disease attributable to NSAIDs. Gastroenterol. Clin. North Am. 1996 Jun; 25(2): 373-96. PMID: 9229579, ISSN: 0889-8553.
Smalley WE, Griffin MR, Fought RL, Sullivan L, Ray WA. Effect of a prior-authorization requirement on the use of nonsteroidal antiinflammatory drugs by Medicaid patients. N. Engl. J. Med. 1995 Jun 6/15/1995; 332(24): 1612-7. PMID: 7753141, DOI: 10.1056/NEJM199506153322406, ISSN: 0028-4793.
Smalley WE, Ray WA, Daugherty JR, Griffin MR. Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons. Am. J. Epidemiol. 1995 Mar 3/15/1995; 141(6): 539-45. PMID: 7900721, ISSN: 0002-9262.
Griffin MR, Smalley WE. Drugs and ulcers: clues about mucosal protection from epidemiologic studies. J. Clin. Gastroenterol. 1995; 21 Suppl 1: S113-9. PMID: 8775002, ISSN: 0192-0790.
Prazma J, Smalley WE, Covington S, Pillsbury HC. Cochlear blood flow. The effect of six hours of noise exposure. Arch. Otolaryngol. Head Neck Surg. 1988 Jun; 114(6): 657-60. PMID: 3365338, ISSN: 0886-4470.
Valenzuela GA, Smalley WE, Schain DC, Vance ML, McCallum RW. Reversibility of gastric dysmotility in cortisol deficiency. Am. J. Gastroenterol. 1987 Oct; 82(10): 1066-8. PMID: 2821798, ISSN: 0002-9270.