Justin M. M. Cates, M.D., Ph.D.



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Faculty Appointments
Professor of Pathology, Microbiology and Immunology
Ph.D., Cell, Molecular and Developmental Biology, Tufts University, Medford, MassachusettsM.D., Medicine, Tufts University School of Medicine, Boston, MassachusettsB.S., Biology, Tufts University, Medford, Massachusetts
Office Address
Department of Pathology C-3322 MCN
Vanderbilt University Medical Center
1161 21st Ave S.
Nashville, TN 37232
Research Keywords
Bone and soft tissue tumors; Sarcoma
Clinical Research Keywords
Orthopedic pathology; bone and soft tissue tumors; sarcoma
Cates JMM. Modeling Continuous Prognostic Factors in Survival Analysis: Implications for Tumor Staging and Assessing Chemotherapy Effect in Osteosarcoma. Am. J. Surg. Pathol. 2018 Apr; 42(4): 485-91. PMID: 29200101, DOI: 10.1097/PAS.0000000000000995, ISSN: 1532-0979.

Wang Y, Vnencak-Jones CL, Cates JM, Shi C. Deciphering Elevated Microsatellite Alterations at Selected Tetra/Pentanucleotide Repeats, Microsatellite Instability, and Loss of Heterozygosity in Colorectal Cancers. J Mol Diagn [print-electronic]. 2018 Feb 2/20/2018; PMID: 29474982, PII: S1525-1578(17)30446-4, DOI: 10.1016/j.jmoldx.2018.02.001, ISSN: 1943-7811.

Cates JMM. The AJCC 8th Edition Staging System for Soft Tissue Sarcoma of the Extremities or Trunk: A Cohort Study of the SEER Database. J Natl Compr Canc Netw. 2018 Feb; 16(2): 144-52. PMID: 29439175, PII: 16/2/144, DOI: 10.6004/jnccn.2017.7042, ISSN: 1540-1413.

Cates JMM. Performance Analysis of the American Joint Committee on Cancer 8th Edition Staging System for Retroperitoneal Sarcoma and Development of a New Staging Algorithm for Sarcoma-Specific Survival. Ann. Surg. Oncol [print-electronic]. 2017 Dec; 24(13): 3880-7. PMID: 29058143, PII: 10.1245/s10434-017-6116-8, DOI: 10.1245/s10434-017-6116-8, ISSN: 1534-4681.

Gonzalez RS, Cates JMM, Revetta F, McMahon LA, Washington K. Gastric Carcinomas With Lymphoid Stroma: Categorization and Comparison With Solid-Type Colonic Carcinomas. Am. J. Clin. Pathol. 2017 Nov 11/20/2017; 148(6): 477-84. PMID: 29126141, PII: 4602853, DOI: 10.1093/ajcp/aqx096, ISSN: 1943-7722.

Nohr E, Lee LH, Cates JM, Perizzolo M, Itani D. Diagnostic value of histone 3 mutations in osteoclast-rich bone tumors. Hum. Pathol [print-electronic]. 2017 Oct; 68: 119-27. PMID: 28882701, PII: S0046-8177(17)30316-7, DOI: 10.1016/j.humpath.2017.08.030, ISSN: 1532-8392.

Cates JM. Reporting Surgical Resection Margin Status for Osteosarcoma: Comparison of the AJCC, MSTS, and Margin Distance Methods. Am. J. Surg. Pathol. 2017 May; 41(5): 633-42. PMID: 28125453, DOI: 10.1097/PAS.0000000000000815, ISSN: 1532-0979.

Janssen ML, van Broekhoven DL, Cates JM, Bramer WM, Nuyttens JJ, Gronchi A, Salas S, Bonvalot S, Grünhagen DJ, Verhoef C. Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis. Br J Surg. 2017 Mar; 104(4): 347-57. PMID: 28199014, DOI: 10.1002/bjs.10477, ISSN: 1365-2168.

Cates JM. Comparison of the AJCC, MSTS, and Modified Spanier Systems for Clinical and Pathologic Staging of Osteosarcoma. Am. J. Surg. Pathol. 2017 Mar; 41(3): 405-13. PMID: 28195881, PII: 00000478-201703000-00013, DOI: 10.1097/PAS.0000000000000774, ISSN: 1532-0979.

Hunter JB, O'Connell BP, Chow WN, Weaver KD, Cates JM, Wanna GB. Myopericytoma of the Internal Auditory Canal. Otol. Neurotol. 2017 Feb; 38(2): e5-e7. PMID: 27832007, DOI: 10.1097/MAO.0000000000001281, ISSN: 1537-4505.

Gonzalez RS, Huh WJ, Cates JM, Washington K, Beauchamp RD, Coffey RJ, Shi C. Micropapillary colorectal carcinoma: clinical, pathological and molecular properties, including evidence of epithelial-mesenchymal transition. Histopathology [print-electronic]. 2017 Jan; 70(2): 223-31. PMID: 27560620, DOI: 10.1111/his.13068, ISSN: 1365-2559.

Fata CR, Gonzalez RS, Liu E, Cates JM, Shi C. Mesenteric Tumor Deposits in Midgut Small Intestinal Neuroendocrine Tumors Are a Stronger Indicator Than Lymph Node Metastasis for Liver Metastasis and Poor Prognosis. Am. J. Surg. Pathol. 2017 Jan; 41(1): 128-33. PMID: 27684993, PMCID: PMC5159256, DOI: 10.1097/PAS.0000000000000751, ISSN: 1532-0979.

Cates JM, Dupont WD. Cytologic anaplasia is a prognostic factor in osteosarcoma biopsies, but mitotic rate or extent of spontaneous tumor necrosis are not: a critique of the College of American Pathologists Bone Biopsy template. Mod. Pathol [print-electronic]. 2017 Jan; 30(1): 52-9. PMID: 27658478, PII: modpathol2016163, DOI: 10.1038/modpathol.2016.163, ISSN: 1530-0285.

Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS. SIgA Deficiency in Individual Small Airways is Associated with Persistent Inflammation and Remodeling. Am. J. Respir. Crit. Care Med [print-electronic]. 2016 Dec 12/2/2016; PMID: 27911098, DOI: 10.1164/rccm.201604-0759OC, ISSN: 1535-4970.

Arnold Egloff SA, Du L, Loomans HA, Starchenko A, Su PF, Ketova T, Knoll PB, Wang J, Haddad AQ, Fadare O, Cates JM, Lotan Y, Shyr Y, Clark PE, Zijlstra A. Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer. Oncotarget [print-electronic]. 2016 Nov 11/24/2016; PMID: 27894096, PII: 13546, DOI: 10.18632/oncotarget.13546, ISSN: 1949-2553.

Johnson DB, Frampton GM, Rioth MJ, Yusko E, Xu Y, Guo X, Ennis RC, Fabrizio D, Chalmers ZR, Greenbowe J, Ali SM, Balasubramanian S, Sun JX, He Y, Frederick DT, Puzanov I, Balko JM, Cates JM, Ross JS, Sanders C, Robins H, Shyr Y, Miller VA, Stephens PJ, Sullivan RJ, Sosman JA, Lovly CM. Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade. Cancer Immunol Res [print-electronic]. 2016 Nov; 4(11): 959-67. PMID: 27671167, PMCID: PMC5134329, PII: 2326-6066.CIR-16-0143, DOI: 10.1158/2326-6066.CIR-16-0143, ISSN: 2326-6074.

Yang S, Jiang M, Grabowska MM, Li J, Connelly ZM, Zhang J, Hayward SW, Cates JM, Han G, Yu X. Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo. Oncotarget. 2016 Oct 10/25/2016; 7(43): 70404-19. PMID: 27611945, PII: 11879, DOI: 10.18632/oncotarget.11879, ISSN: 1949-2553.

Qiao J, Grabowska MM, Forestier-Roman IS, Mirosevich J, Case TC, Chung DH, Cates JM, Matusik RJ, Manning HC, Jin R. Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression. Oncotarget. 2016 Sep 9/20/2016; 7(38): 61955-69. PMID: 27542219, PII: 11326, DOI: 10.18632/oncotarget.11326, ISSN: 1949-2553.

Cates JM. Utility of Examination of Biopsy Tracts in Osteosarcoma Resection Specimens. Am. J. Clin. Pathol. 2016 Sep; 146(3): 324-7. PMID: 27543978, PII: aqw119, DOI: 10.1093/ajcp/aqw119, ISSN: 1943-7722.

Mignemi NA, Yuasa M, Baker CE, Moore SN, Ihejirika RC, Oelsner WK, Wallace CS, Yoshii T, Okawa A, Revenko AS, MacLeod AR, Bhattacharjee G, Barnett JV, Schwartz HS, Degen JL, Flick MJ, Cates JM, Schoenecker JG. Plasmin Prevents Dystrophic Calcification After Muscle Injury. J. Bone Miner. Res [print-electronic]. 2016 Aug 8/17/2016; PMID: 27530373, DOI: 10.1002/jbmr.2973, ISSN: 1523-4681.

Weiss V, Dueber J, Wright JP, Cates J, Revetta F, Parikh AA, Merchant NB, Shi C. Immunohistochemical analysis of the Wnt/ß-catenin signaling pathway in pancreatic neuroendocrine neoplasms. World J Gastrointest Oncol. 2016 Aug 8/15/2016; 8(8): 615-22. PMID: 27574554, PMCID: PMC4980652, DOI: 10.4251/wjgo.v8.i8.615.

Cates JM, Schoenecker JG. Proximal location in extremity long bones is a poor prognostic factor for osteosarcoma: A retrospective cohort study of 153 patients. Acta Oncol [print-electronic]. 2016 Aug; 55(8): 1036-9. PMID: 27145235, DOI: 10.3109/0284186X.2016.1156740, ISSN: 1651-226X.

Cates JM. Pathologic fracture a poor prognostic factor in osteosarcoma: Misleading conclusions from meta-analyses?. Eur J Surg Oncol [print-electronic]. 2016 Jun; 42(6): 883-8. PMID: 26895688, PII: S0748-7983(16)00058-5, DOI: 10.1016/j.ejso.2016.01.016, ISSN: 1532-2157.

Warrick JI, Raman JD, Kaag M, Bruggeman T, Cates J, Clark P, DeGraff DJ. Enhancer of zeste homolog 2 (EZH2) expression in bladder cancer. Urol. Oncol [print-electronic]. 2016 Jun; 34(6): 258.e1-6. PMID: 26976725, PII: S1078-1439(16)00044-2, DOI: 10.1016/j.urolonc.2016.02.011, ISSN: 1873-2496.

Lebus GF, Cates JM, Lee DH. Aneurysmal Bone Cyst of the Scaphoid: A Case Report. JBJS Case Connect. 2016 Apr; 6(2): e49. PMID: 29252681, PII: 01709767-201600620-00027, DOI: 10.2106/JBJS.CC.15.00238, ISSN: 2160-3251.

Berndt A, Ackert-Bicknell C, Silva KA, Kennedy VE, Sundberg BA, Cates JM, Schofield PN, Sundberg JP. Genetic determinants of fibro-osseous lesions in aged inbred mice. Exp. Mol. Pathol [print-electronic]. 2016 Feb; 100(1): 92-100. PMID: 26589134, PII: S0014-4800(15)00229-4, DOI: 10.1016/j.yexmp.2015.11.018, ISSN: 1096-0945.

Amato KR, Wang S, Tan L, Hastings AK, Song W, Lovly CM, Meador CB, Ye F, Lu P, Balko JM, Colvin DC, Cates JM, Pao W, Gray NS, Chen J. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res [print-electronic]. 2016 Jan 1/15/2016; 76(2): 305-18. PMID: 26744526, PMCID: PMC4715957, PII: 0008-5472.CAN-15-0717, DOI: 10.1158/0008-5472.CAN-15-0717, ISSN: 1538-7445.

Gonzalez RS, Cates JM, Washington MK, Beauchamp RD, Coffey RJ, Shi C. Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. Histopathology [print-electronic]. 2016 Jan; 68(2): 183-90. PMID: 25913616, PMCID: PMC4619179, DOI: 10.1111/his.12725, ISSN: 1365-2559.

Moore SN, Hawley GD, Smith EN, Mignemi NA, Ihejirika RC, Yuasa M, Cates JM, Liu X, Schoenecker JG. Validation of a Radiography-Based Quantification Designed to Longitudinally Monitor Soft Tissue Calcification in Skeletal Muscle. PLoS ONE. 2016; 11(7): e0159624. PMID: 27438007, PMCID: PMC4954695, PII: PONE-D-16-05659, DOI: 10.1371/journal.pone.0159624, ISSN: 1932-6203.

Grabowska MM, Kelly SM, Reese AL, Cates JM, Case TC, Zhang J, DeGraff DJ, Strand DW, Miller NL, Clark PE, Hayward SW, Gronostajski RM, Anderson PD, Matusik RJ. Nfib regulates transcriptional networks that control the development of prostatic hyperplasia. Endocrinology [print-electronic]. 2015 Dec 12/17/2015; en20151312. PMID: 26677878, DOI: 10.1210/en.2015-1312, ISSN: 1945-7170.

Du RH, Richmond BW, Blackwell TS, Cates JM, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS, Polosukhin VV. Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease. Virchows Arch [print-electronic]. 2015 Dec; 467(6): 657-65. PMID: 26432569, PII: 10.1007/s00428-015-1854-0, DOI: 10.1007/s00428-015-1854-0, ISSN: 1432-2307.

Bastakoty D, Saraswati S, Cates J, Lee E, Nanney LB, Young PP. Inhibition of Wnt/ß-catenin pathway promotes regenerative repair of cutaneous and cartilage injury. FASEB J [print-electronic]. 2015 Dec; 29(12): 4881-92. PMID: 26268926, PMCID: PMC4653050, PII: fj.15-275941, DOI: 10.1096/fj.15-275941, ISSN: 1530-6860.

Lyle PL, Bridge JA, Simpson JF, Cates JM, Sanders ME. Liposarcomatous differentiation in malignant phyllodes tumors is unassociated with MDM2 or CDK4 amplification. Histopathology [print-electronic]. 2015 Nov 11/6/2015; PMID: 26542423, DOI: 10.1111/his.12898, ISSN: 1365-2559.

Cates JM. Prognostic factors for second recurrence after surgical resection of recurrent desmoid-type fibromatosis. Pathol. Oncol. Res [print-electronic]. 2015 Sep; 21(4): 1085-90. PMID: 25916970, DOI: 10.1007/s12253-015-9939-2, ISSN: 1532-2807.

Cates JM, Troutman KA. Quality Management of the Immunohistochemistry Laboratory: A Practical Guide. Appl. Immunohistochem. Mol. Morphol. 2015 Aug; 23(7): 471-80. PMID: 25203427, DOI: 10.1097/PAI.0000000000000111, ISSN: 1533-4058.

Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM. Granular cell tumors overexpress TFE3 without corollary gene rearrangement--Reply [letter]. Hum. Pathol [print-electronic]. 2015 Aug; 46(8): 1243. PMID: 26001332, PII: S0046-8177(15)00126-4, DOI: 10.1016/j.humpath.2015.04.005, ISSN: 1532-8392.

Cates JM, Memoli VA, Gonzalez RS. Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma. Virchows Arch [print-electronic]. 2015 Aug; 467(2): 211-6. PMID: 25940995, DOI: 10.1007/s00428-015-1778-8, ISSN: 1432-2307.

Goldstein JA, Cates JM. Differential diagnostic considerations of desmoid-type fibromatosis. Adv Anat Pathol. 2015 Jul; 22(4): 260-6. PMID: 26050263, PII: 00125480-201507000-00004, DOI: 10.1097/PAP.0000000000000077, ISSN: 1533-4031.

Cates JM. Pregnancy does not increase the local recurrence rate after surgical resection of desmoid-type fibromatosis. Int. J. Clin. Oncol [print-electronic]. 2015 Jun; 20(3): 617-22. PMID: 25124238, DOI: 10.1007/s10147-014-0743-x, ISSN: 1437-7772.

Reddy OL, Cates JM, Gellert LL, Crist HS, Yang Z, Yamashita H, Taylor JA, Smith JA, Chang SS, Cookson MS, You C, Barocas DA, Grabowska MM, Ye F, Wu XR, Yi Y, Matusik RJ, Kaestner KH, Clark PE, DeGraff DJ. Loss of FOXA1 Drives Sexually Dimorphic Changes in Urothelial Differentiation and Is an Independent Predictor of Poor Prognosis in Bladder Cancer. Am. J. Pathol. 2015 May; 185(5): 1385-95. PMID: 25907831, PMCID: PMC4419202, PII: S0002-9440(15)00083-8, DOI: 10.1016/j.ajpath.2015.01.014, ISSN: 1525-2191.

Yu X, Cates JM, Morrissey C, You C, Grabowska MM, Zhang J, DeGraff DJ, Strand DW, Franco OE, Lin-Tsai O, Hayward SW, Matusik RJ. SOX2 expression in the developing, adult, as well as, diseased prostate. Prostate Cancer Prostatic Dis [print-electronic]. 2014 Dec; 17(4): 301-9. PMID: 25091041, PMCID: PMC4227931, PII: pcan201429, DOI: 10.1038/pcan.2014.29, ISSN: 1476-5608.

Cates JM, Stricker TP. Surgical resection margins in desmoid-type fibromatosis: a critical reassessment. Am. J. Surg. Pathol. 2014 Dec; 38(12): 1707-14. PMID: 25392923, PII: 00000478-201412000-00016, DOI: 10.1097/PAS.0000000000000276, ISSN: 1532-0979.

Cates JM, Stricker TP, Sturgeon D, Coffin CM. Desmoid-type fibromatosis-associated Gardner fibromas: prevalence and impact on local recurrence. Cancer Lett [print-electronic]. 2014 Oct 10/28/2014; 353(2): 176-81. PMID: 25064609, PII: S0304-3835(14)00367-X, DOI: 10.1016/j.canlet.2014.07.020, ISSN: 1872-7980.

Yuasa M, Mignemi NA, Barnett JV, Cates JM, Nyman JS, Okawa A, Yoshii T, Schwartz HS, Stutz CM, Schoenecker JG. The temporal and spatial development of vascularity in a healing displaced fracture. Bone [print-electronic]. 2014 Oct; 67: 208-21. PMID: 25016962, PII: S8756-3282(14)00253-1, DOI: 10.1016/j.bone.2014.07.002, ISSN: 1873-2763.

Ohba T, Cates JM, Cole HA, Slosky DA, Haro H, Ando T, Schwartz HS, Schoenecker JG. Autocrine VEGF/VEGFR1 signaling in a subpopulation of cells associates with aggressive osteosarcoma. Mol. Cancer Res [print-electronic]. 2014 Aug; 12(8): 1100-11. PMID: 24759089, PII: 1541-7786.MCR-14-0037, DOI: 10.1158/1541-7786.MCR-14-0037, ISSN: 1557-3125.

Cole HA, Ohba T, Nyman JS, Hirotaka H, Cates JM, Flick MJ, Degen JL, Schoenecker JG. Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis in mice. Arthritis & rheumatology (Hoboken, N.J.). 2014 Aug; 66(8): 2222-33. PMID: 24664548, PMCID: PMC4474376, DOI: 10.1002/art.38639, ISSN: 2326-5205.

Ettinger DS, Handorf CR, Agulnik M, Bowles DW, Cates JM, Cristea M, Dotan E, Eaton KD, Fidias PM, Gierada D, Gilcrease GW, Godby K, Iyer R, Lenzi R, Phay J, Rashid A, Saltz L, Schwab RB, Shulman LN, Smerage JB, Stevenson MM, Varadhachary GR, Zager JS, Zhen WK, Bergman MA, Freedman-Cass DA, . Occult primary, version 3.2014. J Natl Compr Canc Netw. 2014 Jul; 12(7): 969-74. PMID: 24994917, PII: 12/7/969.

DeGraff DJ, Grabowska MM, Case TC, Yu X, Herrick MK, Hayward WJ, Strand DW, Cates JM, Hayward SW, Gao N, Walter MA, Buttyan R, Yi Y, Kaestner KH, Matusik RJ. FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Lab. Invest [print-electronic]. 2014 Jul; 94(7): 726-39. PMID: 24840332, PMCID: PMC4451837, PII: labinvest201464, DOI: 10.1038/labinvest.2014.64, ISSN: 1530-0307.

Ohba T, Cates JM, Cole HA, Slosky DA, Haro H, Ichikawa J, Ando T, Schwartz HS, Schoenecker JG. Pleiotropic effects of bisphosphonates on osteosarcoma. Bone [print-electronic]. 2014 Jun; 63: 110-20. PMID: 24636958, PII: S8756-3282(14)00079-9, DOI: 10.1016/j.bone.2014.03.005, ISSN: 1873-2763.

Ohba T, Cole HA, Cates JM, Slosky DA, Haro H, Ando T, Schwartz HS, Schoenecker JG. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL. J. Bone Miner. Res. 2014 Jun; 29(6): 1431-45. PMID: 24443409, DOI: 10.1002/jbmr.2182, ISSN: 1523-4681.

Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM. Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study. Hum. Pathol [print-electronic]. 2014 May; 45(5): 1039-44. PMID: 24746209, PII: S0046-8177(14)00024-0, DOI: 10.1016/j.humpath.2013.12.021, ISSN: 1532-8392.

Wang XJ, Hartley K, Holt GE, Fadare O, Cates JM. Intracortical schwannoma of the femur. Skeletal Radiol [print-electronic]. 2014 May; 43(5): 687-91. PMID: 24213555, DOI: 10.1007/s00256-013-1758-5, ISSN: 1432-2161.

Cole HA, Ohba T, Ichikawa J, Nyman JS, Cates JM, Haro H, Schwartz HS, Schoenecker JG. Micro-computed tomography derived anisotropy detects tumor provoked deviations in bone in an orthotopic osteosarcoma murine model. PLoS ONE. 2014; 9(6): e97381. PMID: 24892952, PMCID: PMC4043681, PII: PONE-D-14-04672, DOI: 10.1371/journal.pone.0097381, ISSN: 1932-6203.

Xiang Y, Qiu Q, Jiang M, Jin R, Lehmann BD, Strand DW, Jovanovic B, DeGraff DJ, Zheng Y, Yousif DA, Simmons CQ, Case TC, Yi J, Cates JM, Virostko J, He X, Jin X, Hayward SW, Matusik RJ, George AL, Yi Y. SPARCL1 suppresses metastasis in prostate cancer. Mol Oncol [print-electronic]. 2013 Dec; 7(6): 1019-30. PMID: 23916135, PMCID: PMC3838491, PII: S1574-7891(13)00105-1, DOI: 10.1016/j.molonc.2013.07.008, ISSN: 1878-0261.

Weiss VL, Antonescu CR, Alaggio R, Cates JM, Gaskin D, Stefanovici C, Coffin CM. Myxoinflammatory fibroblastic sarcoma in children and adolescents: clinicopathologic aspects of a rare neoplasm. Pediatr. Dev. Pathol [print-electronic]. 2013 Nov; 16(6): 425-31. PMID: 23919754, DOI: 10.2350/13-06-1353-CR.1, ISSN: 1093-5266.

DeGraff DJ, Cates JM, Mauney JR, Clark PE, Matusik RJ, Adam RM. When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression. Urol. Oncol [print-electronic]. 2013 Aug; 31(6): 802-11. PMID: 21924649, PII: S1078-1439(11)00237-7, DOI: 10.1016/j.urolonc.2011.07.017, ISSN: 1873-2496.

McClain CM, Friedman DB, Hajri T, Coffin CM, Cates JM. Predicting dedifferentiation in liposarcoma: a proteomic approach. Virchows Arch [print-electronic]. 2013 Jul; 463(1): 85-92. PMID: 23709017, DOI: 10.1007/s00428-013-1416-2, ISSN: 1432-2307.

Gehrie EA, Cates JM, Nian H, Olson SJ, Young PP. Blood Group A antigen expression on cardiac endothelium is highly individualized: possible implications for transplantation. Cardiovasc. Pathol [print-electronic]. 2013 Jul; 22(4): 251-6. PMID: 23290353, PII: S1054-8807(12)00144-5, DOI: 10.1016/j.carpath.2012.10.007, ISSN: 1879-1336.

Pruitt FL, He Y, Franco OE, Jiang M, Cates JM, Hayward SW. Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. Prostate [print-electronic]. 2013 Apr; 73(5): 476-88. PMID: 22996917, PMCID: PMC3594371, DOI: 10.1002/pros.22589, ISSN: 1097-0045.

Strand DW, DeGraff DJ, Jiang M, Sameni M, Franco OE, Love HD, Hayward WJ, Lin-Tsai O, Wang AY, Cates JM, Sloane BF, Matusik RJ, Hayward SW. Deficiency in metabolic regulators PPAR¿ and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. Am. J. Pathol [print-electronic]. 2013 Feb; 182(2): 449-59. PMID: 23219716, PMCID: PMC3562729, PII: S0002-9440(12)00801-2, DOI: 10.1016/j.ajpath.2012.10.007, ISSN: 1525-2191.

Cole HA, Yuasa M, Hawley G, Cates JM, Nyman JS, Schoenecker JG. Differential development of the distal and proximal femoral epiphysis and physis in mice. Bone [print-electronic]. 2013 Jan; 52(1): 337-46. PMID: 23079139, PII: S8756-3282(12)01319-1, DOI: 10.1016/j.bone.2012.10.011, ISSN: 1873-2763.

Mignemi NA, Itani DM, Fasig JH, Keedy VL, Hande KR, Whited BW, Homlar KC, Correa H, Coffin CM, Black JO, Yi Y, Halpern JL, Holt GE, Schwartz HS, Schoenecker JG, Cates JM. Signal transduction pathway analysis in desmoid-type fibromatosis: transforming growth factor-ß, COX2 and sex steroid receptors. Cancer Sci [print-electronic]. 2012 Dec; 103(12): 2173-80. PMID: 23035734, PMCID: PMC4278584, DOI: 10.1111/cas.12037, ISSN: 1349-7006.

Kallen ME, Sanders ME, Gonzalez AL, Black JO, Keedy VL, Hande KR, Homlar KC, Halpern JL, Holt GE, Schwartz HS, Coffin CM, Cates JM. Nuclear p63 expression in osteoblastic tumors. Tumour Biol [print-electronic]. 2012 Oct; 33(5): 1639-44. PMID: 22623071, DOI: 10.1007/s13277-012-0419-y, ISSN: 1423-0380.

Cates JM, Black JO, Itani DM, Fasig JH, Keedy VL, Hande KR, Whited BW, Homlar KC, Halpern JL, Holt GE, Schwartz HS, Coffin CM. Signal transduction pathway analysis in fibromatosis: receptor and nonreceptor tyrosine kinases. Hum. Pathol [print-electronic]. 2012 Oct; 43(10): 1711-8. PMID: 22520949, PMCID: PMC4278590, PII: S0046-8177(11)00530-2, DOI: 10.1016/j.humpath.2011.12.021, ISSN: 1532-8392.

Cates JM, Black J, Wolfe CC, Shinohara ET, Holt GE, Keedy VL, Hande KR, Homlar KC, Halpern JL, Schwartz HS, Troutman A, Coffin CM. Morphologic and immunophenotypic analysis of desmoid-type fibromatosis after radiation therapy. Hum. Pathol [print-electronic]. 2012 Sep; 43(9): 1418-24. PMID: 22404950, PII: S0046-8177(11)00462-X, DOI: 10.1016/j.humpath.2011.11.002, ISSN: 1532-8392.

Ichikawa J, Cole HA, Magnussen RA, Mignemi NA, Butler M, Holt GE, O'Rear L, Yuasa M, Pabla B, Haro H, Cates JM, Hamm HE, Schwartz HS, Schoenecker JG. Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: procoagulant nature of osteosarcoma. Cancer [print-electronic]. 2012 May 5/1/2012; 118(9): 2494-506. PMID: 21953059, DOI: 10.1002/cncr.26518, ISSN: 1097-0142.

Rosado FG, Itani DM, Coffin CM, Cates JM. Utility of immunohistochemical staining with FLI1, D2-40, CD31, and CD34 in the diagnosis of acquired immunodeficiency syndrome-related and non-acquired immunodeficiency syndrome-related Kaposi sarcoma. Arch. Pathol. Lab. Med. 2012 Mar; 136(3): 301-4. PMID: 22372906, DOI: 10.5858/arpa.2011-0213-OA, ISSN: 1543-2165.

Gonzalez AL, Cates JM. Osteosarcoma: Differential Diagnostic Considerations. Surg Pathol Clin [print-electronic]. 2012 Mar; 5(1): 117-46. PMID: 26837918, PII: S1875-9181(11)00154-1, DOI: 10.1016/j.path.2011.07.011, ISSN: 1875-9181.

DeGraff DJ, Clark PE, Cates JM, Yamashita H, Robinson VL, Yu X, Smolkin ME, Chang SS, Cookson MS, Herrick MK, Shariat SF, Steinberg GD, Frierson HF, Wu XR, Theodorescu D, Matusik RJ. Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation. PLoS ONE [print-electronic]. 2012; 7(5): e36669. PMID: 22590586, PMCID: PMC3349679, PII: PONE-D-11-23587, DOI: 10.1371/journal.pone.0036669, ISSN: 1932-6203.

Cates JM, Coffin CM. Extraskeletal cartilaginous, osseous, and chordoid tumors in children and adolescents. Pediatr. Dev. Pathol. 2012; 15(1 Suppl): 255-66. PMID: 22420731, DOI: 10.2350/10-07-0875-PB.1, ISSN: 1093-5266.

Cates JM, Coffin CM. Neurogenic tumors of soft tissue. Pediatr. Dev. Pathol. 2012; 15(1 Suppl): 62-107. PMID: 22420725, DOI: 10.2350/11-03-1003-PB.1, ISSN: 1093-5266.

Kallen ME, Nunes Rosado FG, Gonzalez AL, Sanders ME, Cates JM. Occasional staining for p63 in malignant vascular tumors: a potential diagnostic pitfall. Pathol. Oncol. Res [print-electronic]. 2012 Jan; 18(1): 97-100. PMID: 21667345, DOI: 10.1007/s12253-011-9426-3, ISSN: 1532-2807.

Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS. Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med [print-electronic]. 2011 Aug 8/1/2011; 184(3): 317-27. PMID: 21512171, PMCID: PMC3265275, PII: 201010-1629OC, DOI: 10.1164/rccm.201010-1629OC, ISSN: 1535-4970.

Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS. Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. J. Pathol. 2011 Jun; 224(2): 203-11. PMID: 21557221, DOI: 10.1002/path.2863, ISSN: 1096-9896.

Cates JM, Friedman DB, Seeley EH, Dupont WD, Schwartz HS, Holt GE, Caprioli RM, Young PP. Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis. Int J Exp Pathol [print-electronic]. 2010 Aug; 91(4): 335-49. PMID: 20353421, PMCID: PMC2962892, PII: IEP711, DOI: 10.1111/j.1365-2613.2010.00711.x, ISSN: 1365-2613.

Tatsas AD, Keedy VL, Florell SR, Simpson JF, Coffin CM, Kelley MC, Cates JM. Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma. J. Cutan. Pathol [print-electronic]. 2010 Aug; 37(8): 901-6. PMID: 20175826, PII: CUP1512, DOI: 10.1111/j.1600-0560.2010.01512.x, ISSN: 1600-0560.

Sommer J, Itani DM, Homlar KC, Keedy VL, Halpern JL, Holt GE, Schwartz HS, Coffin CM, Kelley MJ, Cates JM. Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma. J. Pathol. 2010 Apr; 220(5): 608-17. PMID: 20140939, DOI: 10.1002/path.2679, ISSN: 1096-9896.

Tsiatis AC, Herceg ME, Keedy VL, Halpern JL, Holt GE, Schwartz HS, Cates JM. Prognostic significance of c-Myc expression in soft tissue leiomyosarcoma. Mod. Pathol [print-electronic]. 2009 Nov; 22(11): 1432-8. PMID: 19633646, PII: modpathol2009113, DOI: 10.1038/modpathol.2009.113, ISSN: 1530-0285.

Adelani MA, Schultenover SJ, Holt GE, Cates JM. Primary leiomyosarcoma of extragnathic bone: clinicopathologic features and reevaluation of prognosis. Arch. Pathol. Lab. Med. 2009 Sep; 133(9): 1448-56. PMID: 19722754, PII: 2008-0518-RAR, DOI: 10.1043/1543-2165-133.9.1448, ISSN: 1543-2165.

Herceg ME, Tsiatis AC, Halpern JL, Holt GE, Schwartz HS, Keedy VL, Cates JM. Cyclooxygenase 2 expression in soft tissue leiomyosarcoma. Anticancer Res. 2009 Aug; 29(8): 2913-7. PMID: 19661295, PII: 29/8/2913, ISSN: 1791-7530.

Li B, Vincent A, Cates J, Brantley-Sieders DM, Polk DB, Young PP. Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site. Cancer Res. 2009 Jan 1/1/2009; 69(1): 338-48. PMID: 19118019, PMCID: PMC2651676, PII: 69/1/338, DOI: 10.1158/0008-5472.CAN-08-1565, ISSN: 1538-7445.

Cates JM, Byrd RH, Fohn LE, Tatsas AD, Washington MK, Black CC. Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma. Pancreas. 2009 Jan; 38(1): e1-6. PMID: 18766116, PMCID: PMC2882851, DOI: 10.1097/MPA.0b013e3181878b7f, ISSN: 1536-4828.

Alfaro MP, Pagni M, Vincent A, Atkinson J, Hill MF, Cates J, Davidson JM, Rottman J, Lee E, Young PP. The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2008 Nov 11/25/2008; 105(47): 18366-71. PMID: 19017790, PMCID: PMC2587631, PII: 0803437105, DOI: 10.1073/pnas.0803437105, ISSN: 1091-6490.

Cates JM, Dupont WD, Barnes JW, Edmunds HS, Fasig JH, Olson SJ, Black CC. Markers of epithelial-mesenchymal transition and epithelial differentiation in sarcomatoid carcinoma: utility in the differential diagnosis with sarcoma. Appl. Immunohistochem. Mol. Morphol. 2008 May; 16(3): 251-62. PMID: 18301244, DOI: 10.1097/PAI.0b013e318156e9b4, ISSN: 1533-4058.

Hoene KA, Kaufman MR, Cates JM, Chang SS. Inflammatory myofibroblastic tumor of the urinary bladder in a 27-year-old woman with systemic lupus erythematosus. Int. J. Urol. 2008 Feb; 15(2): 182-4. PMID: 18269462, PII: IJU1967, DOI: 10.1111/j.1442-2042.2007.01967.x, ISSN: 1442-2042.

Fasig JH, Dupont WD, LaFleur BJ, Olson SJ, Cates JM. Immunohistochemical analysis of receptor tyrosine kinase signal transduction activity in chordoma. Neuropathol. Appl. Neurobiol [print-electronic]. 2008 Feb; 34(1): 95-104. PMID: 17973908, PII: NAN873, DOI: 10.1111/j.1365-2990.2007.00873.x, ISSN: 0305-1846.

Tsiatis AC, Atkinson JB, Wright JK, Cates JM. Primary hepatic myxoid leiomyosarcoma: a case report and review of the literature. Ultrastruct Pathol. 2008 Jan; 32(1): 25-8. PMID: 18300035, PII: 790903641, DOI: 10.1080/01913120701696122, ISSN: 1521-0758.

Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J. Clin. Invest. 2008 Jan; 118(1): 64-78. PMID: 18079969, PMCID: PMC2129239, DOI: 10.1172/JCI33154, ISSN: 0021-9738.

Noordzij JP, Cates JM, Cohen SM, Bennett ML, Ries WM, Russell PT, Haynes D, Garrett CG, Ossoff RH. Preparation techniques for the injection of human autologous cartilage: an ex vivo feasibility study. Laryngoscope. 2008 Jan; 118(1): 185-8. PMID: 17975513, DOI: 10.1097/MLG.0b013e318155a25b, ISSN: 0023-852X.

Fasig JH, Dupont WD, Olson SJ, Lafleur BJ, Cates JM. Steroid hormone receptor and COX-2 expression in chordoma. Am. J. Clin. Pathol. 2007 Sep; 128(3): 375-81. PMID: 17709310, PII: H2556481807H6452, DOI: 10.1309/8T2NPHLK5X5WQ3E7, ISSN: 0002-9173.

Pitchford CW, Schwartz HS, Atkinson JB, Cates JM. Soft tissue perineurioma in a patient with neurofibromatosis type 2: a tumor not previously associated with the NF2 syndrome. Am. J. Surg. Pathol. 2006 Dec; 30(12): 1624-9. PMID: 17122521, PII: 00000478-200612000-00018, DOI: 10.1097/01.pas.0000213340.70852.d4, ISSN: 0147-5185.

Cates JM, Coffing BN, Harris BT, Black CC. Calretinin expression in tumors of adipose tissue. Hum. Pathol. 2006 Mar; 37(3): 312-21. PMID: 16613326, ISSN: 0046-8177.

Pipas JM, Barth RJ, Zaki B, Tsapakos MJ, Suriawinata AA, Bettmann MA, Cates JM, Ripple GH, Sutton JE, Gordon SR, McDonnell CE, Perez RP, Redfield N, Meyer LP, Marshall JF, Cole BF, Colacchio TA. Docetaxel/Gemcitabine followed by gemcitabine and external beam radiotherapy in patients with pancreatic adenocarcinoma. Ann. Surg. Oncol [print-electronic]. 2005 Dec; 12(12): 995-1004. PMID: 16252135, DOI: 10.1245/ASO.2005.04.503, ISSN: 1068-9265.

Lin JT, Kitzmiller TJ, Cates JM, Gorham JD. MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury. Lab. Invest. 2005 Apr; 85(4): 550-61. PMID: 15696185, PII: 3700246, DOI: 10.1038/labinvest.3700246, ISSN: 0023-6837.

Cates JM, Williams TL, Suriawinata AA. Intraductal papillary mucinous adenoma that arises from pancreatic heterotopia within a meckel diverticulum. Arch. Pathol. Lab. Med. 2005 Mar; 129(3): e67-9. PMID: 15737052, PII: CR4131, DOI: 10.1043/1543-2165(2005)1292.0.CO;2, ISSN: 1543-2165.

Gutmann EJ, Cates JM. Initial diagnosis of breast cancer via cytological examination of a pleural effusion: a rare event facilitated by recognition of an unusual morphological pattern. Diagn. Cytopathol. 2005 Mar; 32(3): 177-81. PMID: 15690336, DOI: 10.1002/dc.20207, ISSN: 8755-1039.

Gardner TB, Manning HL, Beelen AP, Cimis RJ, Cates JM, Lewis LD. Ethylene glycol toxicity associated with ischemia, perforation, and colonic oxalate crystal deposition. J. Clin. Gastroenterol. 2004 May; 38(5): 435-9. PMID: 15100524, PII: 00004836-200405000-00009, ISSN: 0192-0790.

Rudner LA, Lin JT, Park IK, Cates JM, Dyer DA, Franz DM, French MA, Duncan EM, White HD, Gorham JD. Necroinflammatory liver disease in BALB/c background, TGF-beta 1-deficient mice requires CD4+ T cells. J. Immunol. 2003 May 5/1/2003; 170(9): 4785-92. PMID: 12707360, ISSN: 0022-1767.

Ramnath RR, Rosenthal DI, Cates J, Gebhardt M, Quinn RH. Intracortical chondroma simulating osteoid osteoma treated by radiofrequency. Skeletal Radiol [print-electronic]. 2002 Oct; 31(10): 597-602. PMID: 12324830, DOI: 10.1007/s00256-002-0501-4, ISSN: 0364-2348.

Tang P, Hornicek FJ, Gebhardt MC, Cates J, Mankin HJ. Surgical treatment of hemangiomas of soft tissue. Clin. Orthop. Relat. Res. 2002 Jun; (399): 205-10. PMID: 12011711, ISSN: 0009-921X.

Hau MA, Fox EJ, Cates JM, Brigman BE, Mankin HJ. Jaffe-Campanacci syndrome. A case report and review of the literature. J Bone Joint Surg Am. 2002 Apr; 84-A(4): 634-8. PMID: 11940628, ISSN: 0021-9355.

Sami S, Liu G, Hornicek F, Cates JM, Mankin HJ. Membranous lipodystrophy. A case report. J Bone Joint Surg Am. 2002 Apr; 84-A(4): 630-3. PMID: 11940627, ISSN: 0021-9355.

Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM. Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. Radiology. 2001 Nov; 221(2): 463-8. PMID: 11687691, DOI: 10.1148/radiol.2212010262, ISSN: 0033-8419.

Cates JM, Rosenberg AE, O'Connell JX, Nielsen GP. Chondroblastoma-like chondroma of soft tissue: an underrecognized variant and its differential diagnosis. Am. J. Surg. Pathol. 2001 May; 25(5): 661-6. PMID: 11342780, ISSN: 0147-5185.

Cates JM, Damassa DA. Characterization and developmental expression patterns of testicular androgen-binding protein in the Djungarian hamster (Phodopus sungorus). J. Reprod. Fertil. 1997 Nov; 111(2): 291-8. PMID: 9462298, ISSN: 0022-4251.

Cates JM, Damassa DA, Gagin GA, Dempsey RV. Hepatic expression of sex hormone-binding globulin associated with the postnatal surge of serum androgen-binding activity in the Djungarian hamster. J. Steroid Biochem. Mol. Biol. 1995 Nov; 55(2): 147-58. PMID: 7495693, PII: 096007609500166W, ISSN: 0960-0760.

Damassa DA, Cates JM. Sex hormone-binding globulin and male sexual development. Neurosci Biobehav Rev. 1995; 19(2): 165-75. PMID: 7630573, PII: 0149763495000146, ISSN: 0149-7634.

Yu M, Cates J, Leav I, Ho SM. Heterogeneity of [3H]estradiol binding sites in the rat prostate: properties and distribution of type I and type II sites. J. Steroid Biochem. 1989 Sep; 33(3): 449-57. PMID: 2779236, ISSN: 0022-4731.