Chandramohan Natarajan, Ph.D.

Research Assistant Professor

chandramohan.natarajan@vanderbilt.edu
Faculty Appointments
Research Assistant Professor of Neurology
Education
Ph.D., Madras University, Madras, IndiaM.Sc., Annamalai University, Mumbai, IndiaB.Sc., A.V.C. College, Mayiladuthurai, India
Publications
Natarajan C, Yao SY, Sriram S. TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair. PLoS ONE. 2016; 11(3): e0152163. PMID: 27022724, PMCID: PMC4811556, PII: PONE-D-15-54991, DOI: 10.1371/journal.pone.0152163, ISSN: 1932-6203.

Natarajan C, Yao SY, Zhang F, Sriram S. Activation of NOD2/RIPK2 pathway induces mitochondrial injury to oligodendrocyte precursor cells in vitro and CNS demyelination in vivo. J. Neuroimmunol [print-electronic]. 2013 Dec 12/15/2013; 265(1-2): 51-60. PMID: 24169446, PII: S0165-5728(13)00251-8, DOI: 10.1016/j.jneuroim.2013.09.009, ISSN: 1872-8421.

Li J, Parker B, Martyn C, Natarajan C, Guo J. The PMP22 gene and its related diseases. Mol. Neurobiol [print-electronic]. 2013 Apr; 47(2): 673-98. PMID: 23224996, PMCID: PMC3594637, DOI: 10.1007/s12035-012-8370-x, ISSN: 1559-1182.

Natarajan C, Hata AN, Hamm HE, Zent R, Breyer RM. Extracellular loop II modulates GTP sensitivity of the prostaglandin EP3 receptor. Mol. Pharmacol [print-electronic]. 2013 Jan; 83(1): 206-16. PMID: 23087260, PMCID: PMC3533480, PII: mol.112.080473, DOI: 10.1124/mol.112.080473, ISSN: 1521-0111.

Yao SY, Natarajan C, Sriram S. NNOS mediated mitochondrial injury in LPS stimulated oligodendrocytes. Mitochondrion [print-electronic]. 2012 Mar; 12(2): 336-44. PMID: 22289618, PII: S1567-7249(12)00020-7, DOI: 10.1016/j.mito.2012.01.002, ISSN: 1872-8278.

Zhou W, Dowell DR, Huckabee MM, Newcomb DC, Boswell MG, Goleniewska K, Lotz MT, Toki S, Yin H, Yao S, Natarajan C, Wu P, Sriram S, Breyer RM, Fitzgerald GA, Peebles RS. Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis. PLoS ONE [print-electronic]. 2012; 7(5): e33518. PMID: 22590492, PMCID: PMC3349674, PII: PONE-D-10-03779, DOI: 10.1371/journal.pone.0033518, ISSN: 1932-6203.

Natarajan C, Sriram S, Muthian G, Bright JJ. Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia. Glia. 2004 Jan 1/15/2004; 45(2): 188-96. PMID: 14730712, DOI: 10.1002/glia.10316, ISSN: 0894-1491.

Natarajan C, Muthian G, Barak Y, Evans RM, Bright JJ. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. J. Immunol. 2003 Dec 12/1/2003; 171(11): 5743-50. PMID: 14634082, ISSN: 0022-1767.

Natarajan C, Bright JJ. Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J. Immunol. 2002 Jun 6/15/2002; 168(12): 6506-13. PMID: 12055272, ISSN: 0022-1767.

Natarajan C, Bright JJ. Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun. 2002 Apr; 3(2): 59-70. PMID: 11960303, DOI: 10.1038/sj.gene.6363832, ISSN: 1466-4879.