Mark E. Frisse, M.D., M.B.A.


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Faculty Appointments
Professor of Biomedical Informatics Accenture Chair in the Vanderbilt Center for Better Health
M.B.A., Business Administration, Washington University, Saint Louis, MissouriM.S., Computer Science, Stanford University, Stanford, CaliforniaM.D., Medicine, Washington University, Saint Louis, MissouriB.S., Preprofessional Studies, University of Notre Dame, South Bend, Indiana
Office Address
Vanderbilt Center for Better Health
3401 West End Blvd, Suite 290
Nashville, TN 37203-6866
Research Description
Primary research is directed toward an understanding of economic sustainability and toward the development of technical and administrative measures to ensure the integrity of security and privacy efforts. His work is funded through the SHARP research program of the Office of the National Coordinator for Health Information Technology.
Research Keywords
Focused on the intersections among health care informatics, economics, policy, and health care transformation.
Gadd CS, Ho YX, Cala CM, Blakemore D, Chen Q, Frisse ME, Johnson KB. User perspectives on the usability of a regional health information exchange. J Am Med Inform Assoc [print-electronic]. 2011 Sep; 18(5): 711-6. PMID: 21622933, PMCID: PMC3168324, PII: amiajnl-2011-000281, DOI: 10.1136/amiajnl-2011-000281, ISSN: 1527-974X.

Frisse ME, Tang L, Belsito A, Overhage JM. Development and use of a medication history service associated with a health information exchange: architecture and preliminary findings. AMIA Annu Symp Proc. 2010; 2010: 242-5. PMID: 21346977, PMCID: PMC3041403, ISSN: 1942-597X.

Frisse ME. Health information exchange in Memphis: impact on the physician-patient relationship. J Law Med Ethics. 2010; 38(1): 50-7. PMID: 20446983, PII: JLME465, DOI: 10.1111/j.1748-720X.2010.00465.x, ISSN: 1748-720X.

Frisse ME. Health information technology: one step at a time. Health Aff (Millwood) [print-electronic]. 2009 Mar; 28(2): w379-84. PMID: 19273814, PII: hlthaff.28.2.w379, DOI: 10.1377/hlthaff.28.2.w379, ISSN: 1544-5208.

Coffman T, Porter JP, Frisse ME. Reducing HIE costs through real-time data feed visualizations. AMIA Annu Symp Proc. 2008; 913. PMID: 18999214, ISSN: 1942-597X.

Frisse ME, King JK, Rice WB, Tang L, Porter JP, Coffman TA, Assink M, Yang K, Wesley M, Holmes RL, Gadd C, Johnson KB, Estrin VY. A regional health information exchange: architecture and implementation. AMIA Annu Symp Proc. 2008; 212-6. PMID: 18999138, PMCID: PMC2655967, ISSN: 1942-597X.

Frisse ME, Holmes RL. Estimated financial savings associated with health information exchange and ambulatory care referral. J Biomed Inform [print-electronic]. 2007 Dec; 40(6 Suppl): S27-32. PMID: 17942374, PII: S1532-0464(07)00088-3, DOI: 10.1016/j.jbi.2007.08.004, ISSN: 1532-0480.

Hripcsak G, Kaushal R, Johnson KB, Ash JS, Bates DW, Block R, Frisse ME, Kern LM, Marchibroda J, Overhage JM, Wilcox AB. The United Hospital Fund meeting on evaluating health information exchange. J Biomed Inform [print-electronic]. 2007 Dec; 40(6 Suppl): S3-10. PMID: 17919986, PMCID: PMC2140082, PII: S1532-0464(07)00083-4, DOI: 10.1016/j.jbi.2007.08.002, ISSN: 1532-0480.

Porter JP, Starmer J, King J, Frisse ME. Mapping laboratory test codes to LOINC for a regional health information exchange. AMIA Annu Symp Proc. 2007; 1081. PMID: 18694179, ISSN: 1942-597X.

Frisse ME. Comments on return on investment (ROI) as it applies to clinical systems [editorial]. J Am Med Inform Assoc. 2006 May; 13(3): 365-7. PMID: 16501173, PMCID: PMC1513655, PII: M2072, DOI: 10.1197/jamia.M2072, ISSN: 1067-5027.

Frisse ME. State and community-based efforts to foster interoperability. Health Aff (Millwood). 2005 Sep; 24(5): 1190-6. PMID: 16162562, PII: 24/5/1190, DOI: 10.1377/hlthaff.24.5.1190, ISSN: 0278-2715.

Frisse M, Marchibroda J, Welebob E. HIE takes shape in the states. J AHIMA. 2005 Sep; 76(8): 24-8, 30. PMID: 16245576, ISSN: 1060-5487.

Frisse M. Giving more than a nod to the wave of the future. Manag Care. 2005 Jun; 14(6): 39-40, 42, 45. PMID: 16044887, ISSN: 1062-3388.

Cox ER, Frisse M, Behm A, Fairman KA. Over-the-counter pain reliever and aspirin use within a sample of long-term cyclooxygenase 2 users. Arch. Intern. Med. 2004 Jun 6/14/2004; 164(11): 1243-6. PMID: 15197053, PII: 164/11/1243, DOI: 10.1001/archinte.164.11.1243, ISSN: 0003-9926.

Cox ER, Motheral B, Frisse M, Behm A, Mager D. Prescribing COX-2s for patients new to cyclo-oxygenase inhibition therapy. Am J Manag Care. 2003 Nov; 9(11): 735-42. PMID: 14626471, PII: 2487, ISSN: 1088-0224.

Piccirillo JF, Mager DE, Frisse ME, Brophy RH, Goggin A. Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. JAMA. 2001 Oct 10/17/2001; 286(15): 1849-56. PMID: 11597286, PII: joc10674, ISSN: 0098-7484.

McMullin ST, Reichley RM, Watson LA, Steib SA, Frisse ME, Bailey TC. Impact of a Web-based clinical information system on cisapride drug interactions and patient safety. Arch. Intern. Med. 1999 Sep 9/27/1999; 159(17): 2077-82. PMID: 10510994, ISSN: 0003-9926.

Frisse MC. The business value of health care information technology. J Am Med Inform Assoc. 1999 Sep; 6(5): 361-7. PMID: 10495096, PMCID: PMC61379, ISSN: 1067-5027.

Frisse ME. Healthcare in a networked world. J Am Coll Dent. 1999; 66(2): 51-6. PMID: 10506808, ISSN: 0002-7979.

Frisse ME. Technology and physician responsibility. MD Comput. 1998 Jul; 15(4): 212-3. PMID: 9673083, ISSN: 0724-6811.

Frisse ME, Musen MA, Slack WV, Stead WW. How should we organize to do informatics? Report of the ACMI Debate at the 1997 AMIA Fall Symposium. J Am Med Inform Assoc. 1998 May; 5(3): 293-304. PMID: 9609499, PMCID: PMC61303, ISSN: 1067-5027.

McNamee LA, Launsby BD, Frisse ME, Lehmann R, Ebker K. Scaling an expert system data mart: more facilities in real-time. Proc AMIA Symp. 1998; 498-502. PMID: 9929269, PMCID: PMC2232322, ISSN: 1531-605X.

Frisse ME. Computers and productivity: is it time for a reality check?. Acad Med. 1998 Jan; 73(1): 59-64. PMID: 9447203, ISSN: 1040-2446.

Frisse ME, Florance V. A library for internists IX. Recommendations from the American College of Physicians. Ann. Intern. Med. 1997 May 5/15/1997; 126(10): 836-46. PMID: 9148677, ISSN: 0003-4819.

Frisse ME. Re-imagining the medical informatics curriculum. Acad Med. 1997 Jan; 72(1): 36-41. PMID: 9008566, ISSN: 1040-2446.

Frisse ME. What is the Internet learning about you while you are learning about the Internet?. Acad Med. 1996 Oct; 71(10): 1064-7. PMID: 9177639, ISSN: 1040-2446.

Frisse ME. The commerce of ideas: Internets and Intranets. Acad Med. 1996 Jul; 71(7): 749-53. PMID: 9158343, ISSN: 1040-2446.

Frisse ME. Digital libraries & information retrieval. Proc AMIA Annu Fall Symp. 1996; 320-2. PMID: 8947680, PMCID: PMC2233055, ISSN: 1091-8280.

Frisse ME, Tolva JN. The commerce of ideas: copyright in the digital era. Acad Med. 1996 Jan; 71(1): 45-53. PMID: 8540964, ISSN: 1040-2446.

Fuller S, Braude RM, Florance V, Frisse ME. Managing information in the academic medical center: building an integrated information environment. Acad Med. 1995 Oct; 70(10): 887-91. PMID: 7575920, ISSN: 1040-2446.

Florance V, Braude RM, Frisse ME, Fuller S. Educating physicians to use the digital library. Acad Med. 1995 Jul; 70(7): 597-602. PMID: 7612126, ISSN: 1040-2446.

Braude RM, Florance V, Frisse M, Fuller S. The organization of the digital library. Acad Med. 1995 Apr; 70(4): 286-91. PMID: 7718061, ISSN: 1040-2446.

Frisse ME, Braude RM, Florance V, Fuller S. Informatics and medical libraries: changing needs and changing roles. Acad Med. 1995 Jan; 70(1): 30-5. PMID: 7826440, ISSN: 1040-2446.

Frisse ME. Acquiring information management skills. Acad Med. 1994 Oct; 69(10): 803-6. PMID: 7916791, ISSN: 1040-2446.

Frisse ME, Schnase JL, Metcalfe ES. Models for patient records. Acad Med. 1994 Jul; 69(7): 546-50. PMID: 8018260, ISSN: 1040-2446.

Frisse M. Artificial intelligence: boon to practice or threat to autonomy?. Interview by Diana Madden. Internist. 1994 May; 35(5): 11-5. PMID: 10134159, ISSN: 0020-9546.

Metcalfe ES, Frisse ME, Hassan SW, Schnase JL. Academic networks: mosaic and world wide web. Acad Med. 1994 Apr; 69(4): 270-3. PMID: 8155229, ISSN: 1040-2446.

Frisse ME, Kelly EA, Metcalfe ES. An Internet primer: resources and responsibilities. Acad Med. 1994 Jan; 69(1): 20-4. PMID: 8285991, ISSN: 1040-2446.

Jain NL, Murphy JF, Hassan SW, Cunnius EL, Metcalfe ES, Schnase JL, Schoening PA, Spooner SA, Frisse ME. Interactive electronic whiteboards in the medical classroom. Proc Annu Symp Comput Appl Med Care. 1994; 54-8. PMID: 7949986, PMCID: PMC2247856, ISSN: 0195-4210.

Frisse ME. Making networks work. Acad Med. 1993 Oct; 68(10): 764-6. PMID: 8397602, ISSN: 1040-2446.

Cousins SB, Chen W, Frisse ME. A tutorial introduction to stochastic simulation algorithms for belief networks. Artif Intell Med. 1993 Aug; 5(4): 315-40. PMID: 8220686, ISSN: 0933-3657.

Frisse ME. Ubiquitous computing. Acad Med. 1992 Oct; 67(10): 642-4. PMID: 1388524, ISSN: 1040-2446.

Frisse ME. The health of the computer-based patient record. Acad Med. 1992 Jul; 67(7): 441-3. PMID: 1616556, ISSN: 1040-2446.

Frisse ME. Medical informatics in academic health science centers. Acad Med. 1992 Apr; 67(4): 238-41. PMID: 1558592, ISSN: 1040-2446.

Frisse ME, Marrs K, Schoening P. A method for publishing genomic maps. Proc Annu Symp Comput Appl Med Care. 1992; 376-9. PMID: 1482901, PMCID: PMC2247983, ISSN: 0195-4210.

Cousins SB, Frisse ME, Chen W, Mead CN. Stochastic simulation algorithms for query networks. Proc Annu Symp Comput Appl Med Care. 1991; 696-700. PMID: 1807693, PMCID: PMC2247620, ISSN: 0195-4210.

Frisse ME, Cousins SB, Hassan SW. Information retrieval using a "digital book shelf". Proc Annu Symp Comput Appl Med Care. 1991; 803-7. PMID: 1807717, PMCID: PMC2247641, ISSN: 0195-4210.

Frisse ME. The case for hypermedia. Acad Med. 1990 Jan; 65(1): 17-9. PMID: 2403800, ISSN: 1040-2446.

Zimmerman JB, Cousins SB, Hartzell KM, Frisse ME, Kahn MG. A psychophysical comparison of two methods for adaptive histogram equalization. J Digit Imaging. 1989 May; 2(2): 82-91. PMID: 2488161, ISSN: 0897-1889.

Mill WB, Frisse ME. Herpes zoster in Hodgkin's disease. Mo Med. 1978 Oct; 75(10): 515-8. PMID: 703748, ISSN: 0026-6620.

Scheidt WR, Frisse ME. Nitrosylmetalloporphyrins. II. Synthesis and molecular stereochemistry of mitrosyl-alpha, beta, gamma, delta,-tetraphenylporphinatoiron (ii). J. Am. Chem. Soc. 1975 Jan 1/8/1975; 97(1): 17-21. PMID: 1133330, ISSN: 0002-7863.