Haichun Yang, M.D., Ph.D.

Research Assistant Professor

haichun.yang@vanderbilt.edu
Faculty Appointments
Research Assistant Professor of Pathology, Microbiology and Immunology Research Assistant Professor of Pediatrics
Education
Ph.D., Fudan University, Shanghai, ChinaM.D., Shanghai Medical University, Shanghai, ChinaB.S., Shanghai Medical University, Shanghai, China
Office Address
S4305B MCN, Vanderbilt University Medical Center
Nashville, TN 37232
Publications
Al Tuhaifi T, Zhong J, Yang HC, Fogo AB. Effects of Dipeptidyl Peptidase-4 Inhibitor and Angiotensin-Converting Enzyme Inhibitor on Experimental Diabetic Kidney Disease. Lab Invest [print-electronic]. 2024 Feb; 104(2): 100305. PMID: 38109999, PMCID: PMC10922867, PII: S0023-6837(23)00248-9, DOI: 10.1016/j.labinv.2023.100305, ISSN: 1530-0307.

Zhong J, Kirabo A, Yang HC, Fogo AB, Shelton EL, Kon V. Intestinal Lymphatic Dysfunction in Kidney Disease. Circ Res [print-electronic]. 2023 Apr 4/28/2023; 132(9): 1226-45. PMID: 37104557, PMCID: PMC10144305, DOI: 10.1161/CIRCRESAHA.122.321671, ISSN: 1524-4571.

Wang J, Matsushita K, Zhong J, Ma LJ, Yang HC, Fogo AB. Low-Dose Erythropoietin Amplifies Beneficial Effects of Angiotensin II Blockade on Glomerulosclerosis. Lab Invest [print-electronic]. 2023 Feb; 103(2): 100015. PMID: 37039147, PII: S0023-6837(22)00015-0, DOI: 10.1016/j.labinv.2022.100015, ISSN: 1530-0307.

Zhong J, Yang HC, Shelton EL, Matsusaka T, Clark AJ, Yermalitsky V, Mashhadi Z, May-Zhang LS, Linton MF, Fogo AB, Kirabo A, Davies SS, Kon V. Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury. JCI Insight. 2022 Nov 11/8/2022; 7(21): PMID: 36125905, PMCID: PMC9675465, PII: 161878, DOI: 10.1172/jci.insight.161878, ISSN: 2379-3708.

Kon V, Shelton EL, Pitzer A, Yang HC, Kirabo A. Inflammation, Lymphatics, and Cardiovascular Disease: Amplification by Chronic Kidney Disease. Curr Hypertens Rep [print-electronic]. 2022 Oct; 24(10): 455-63. PMID: 35727522, PMCID: PMC9615424, PII: 10.1007/s11906-022-01206-4, DOI: 10.1007/s11906-022-01206-4, ISSN: 1534-3111.

Tang X, VanBeek C, Haas M, Cook HT, Zou J, Yang H, Fogo AB. Cell-Mediated Glomerulonephritis Without Immune Complexes in Native Kidney Biopsies: A Report of 7 Cases. Am J Kidney Dis [print-electronic]. 2022 Sep; 80(3): 416-21. PMID: 34974034, PII: S0272-6386(21)01050-7, DOI: 10.1053/j.ajkd.2021.11.009, ISSN: 1523-6838.

Badal SS, Al Tuhaifi T, Yu YF, Lopez D, Plato CT, Joly K, Breckenridge DG, Yang HC, Liles JT, Fogo AB. Selonsertib Enhances Kidney Protection Beyond Standard of Care in a Hypertensive, Secondary Glomerulosclerosis CKD Model. Kidney360. 2022 Jul 7/28/2022; 3(7): 1169-82. PMID: 35919527, PMCID: PMC9337896, PII: 02200512-202207000-00010, DOI: 10.34067/KID.0001032022, ISSN: 2641-7650.

Zhu X, Gao D, Albertazzi V, Zhong J, Ma LJ, Du L, Shyr Y, Kon V, Yang HC, Fogo AB. Podocyte-Related Mechanisms Underlying Survival Benefit of Long-Term Angiotensin Receptor Blocker. Int J Mol Sci. 2022 May 5/27/2022; 23(11): PMID: 35682697, PMCID: PMC9181646, PII: ijms23116018, DOI: 10.3390/ijms23116018, ISSN: 1422-0067.

McLarnon SR, Wilson K, Patel B, Sun J, Sartain CL, Mejias CD, Musall JB, Sullivan JC, Wei Q, Chen JK, Hyndman KA, Marshall B, Yang H, Fogo AB, O'Connor PM. Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation. J Am Soc Nephrol [print-electronic]. 2022 Apr; 33(4): 769-85. PMID: 35115326, PMCID: PMC8970460, PII: 00001751-202204000-00013, DOI: 10.1681/ASN.2021081089, ISSN: 1533-3450.

Borza CM, Bolas G, Bock F, Zhang X, Akabogu FC, Zhang MZ, de Caestecker M, Yang M, Yang H, Lee E, Gewin L, Fogo AB, McDonald WH, Zent R, Pozzi A. DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3. JCI Insight. 2022 Feb 2/8/2022; 7(3): PMID: 34941574, PMCID: PMC8855801, PII: 150887, DOI: 10.1172/jci.insight.150887, ISSN: 2379-3708.

Liu J, Shelton EL, Crescenzi R, Colvin DC, Kirabo A, Zhong J, Delpire EJ, Yang HC, Kon V. Kidney Injury Causes Accumulation of Renal Sodium That Modulates Renal Lymphatic Dynamics. Int J Mol Sci. 2022 Jan 1/27/2022; 23(3): PMID: 35163352, PMCID: PMC8836121, PII: ijms23031428, DOI: 10.3390/ijms23031428, ISSN: 1422-0067.

Lu Y, Yang H, Asad Z, Zhu Z, Yao T, Xu J, Fogo AB, Huo Y. Holistic fine-grained global glomerulosclerosis characterization: from detection to unbalanced classification. J Med Imaging (Bellingham) [print-electronic]. 2022 Jan; 9(1): 14005. PMID: 35237706, PMCID: PMC8853712, PII: 21239RR, DOI: 10.1117/1.JMI.9.1.014005, ISSN: 2329-4302.

Liu J, Zhong J, Yang H, Wang D, Zhang Y, Yang Y, Xing G, Kon V. Biotic Supplements in Patients With Chronic Kidney Disease: Meta-Analysis of Randomized Controlled Trials. J Ren Nutr [print-electronic]. 2022 Jan; 32(1): 10-21. PMID: 34666930, PMCID: PMC9793596, PII: S1051-2276(21)00219-3, DOI: 10.1053/j.jrn.2021.08.005, ISSN: 1532-8503.

Taguchi K, Elias BC, Krystofiak E, Qian S, Sant S, Yang H, Fogo AB, Brooks CR. Quantitative super-resolution microscopy reveals promoting mitochondrial interconnectivity protects against AKI. Kidney360 [print-electronic]. 2021 Dec; 2(12): 1892-907. PMID: 35342885, PMCID: PMC8953106, PII: 02200512-202112000-00007, DOI: 10.34067/KID.0001602021, ISSN: 2641-7650.

Neumann EK, Patterson NH, Allen JL, Migas LG, Yang H, Brewer M, Anderson DM, Harvey J, Gutierrez DB, Harris RC, deCaestecker MP, Fogo AB, Van de Plas R, Caprioli RM, Spraggins JM. Protocol for multimodal analysis of human kidney tissue by imaging mass spectrometry and CODEX multiplexed immunofluorescence. STAR Protoc. 2021 Sep 9/17/2021; 2(3): 100747. PMID: 34430920, PMCID: PMC8371244, PII: S2666-1667(21)00454-8, DOI: 10.1016/j.xpro.2021.100747, ISSN: 2666-1667.

Zhong J, Yang HC, Yermalitsky V, Shelton EL, Otsuka T, Wiese CB, May-Zhang LS, Banan B, Abumrad N, Huang J, Cavnar AB, Kirabo A, Yancey PG, Fogo AB, Vickers KC, Linton MF, Davies SS, Kon V. Kidney injury-mediated disruption of intestinal lymphatics involves dicarbonyl-modified lipoproteins. Kidney Int [print-electronic]. 2021 Sep; 100(3): 585-96. PMID: 34102217, PMCID: PMC8447488, PII: S0085-2538(21)00577-9, DOI: 10.1016/j.kint.2021.05.028, ISSN: 1523-1755.

Yang H, Chen R, Li D, Wang Z. Subtype-GAN: a deep learning approach for integrative cancer subtyping of multi-omics data. Bioinformatics. 2021 Aug 8/25/2021; 37(16): 2231-7. PMID: 33599254, PII: 6143031, DOI: 10.1093/bioinformatics/btab109, ISSN: 1367-4811.

De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation chemistry for the development of prodrugs capable of in vivo delivery of carbon monoxide utilizing sweeteners as carrier molecules. Chem Sci. 2021 Aug 8/11/2021; 12(31): 10649-54. PMID: 34447558, PMCID: PMC8356820, PII: d1sc02711e, DOI: 10.1039/d1sc02711e, ISSN: 2041-6520.

Kon V, Yang HC, Smith LE, Vickers KC, Linton MF. High-Density Lipoproteins in Kidney Disease. Int J Mol Sci. 2021 Jul 7/30/2021; 22(15): PMID: 34360965, PMCID: PMC8348850, PII: ijms22158201, DOI: 10.3390/ijms22158201, ISSN: 1422-0067.

Huo Y, Deng R, Liu Q, Fogo AB, Yang H. AI applications in renal pathology. Kidney Int [print-electronic]. 2021 Jun; 99(6): 1309-20. PMID: 33581198, PMCID: PMC8154730, PII: S0085-2538(21)00181-2, DOI: 10.1016/j.kint.2021.01.015, ISSN: 1523-1755.

Qi C, Alsomali F, Zhong J, Harris RC, Kon V, Yang H, Fogo AB. Increased dishevelled associated activator of morphogenesis 2, a new podocyte-associated protein, in diabetic nephropathy. Nephrol Dial Transplant. 2021 May 5/27/2021; 36(6): 1006-16. PMID: 33544843, PMCID: PMC8599908, PII: 6129267, DOI: 10.1093/ndt/gfab014, ISSN: 1460-2385.

Zou J, Yang J, Zhu X, Zhong J, Elshaer A, Matsusaka T, Pastan I, Haase VH, Yang HC, Fogo AB. Stabilization of hypoxia-inducible factor ameliorates glomerular injury sensitization after tubulointerstitial injury. Kidney Int [print-electronic]. 2021 Mar; 99(3): 620-31. PMID: 33137336, PMCID: PMC7914150, PII: S0085-2538(20)31240-0, DOI: 10.1016/j.kint.2020.09.031, ISSN: 1523-1755.

Jha A, Yang H, Deng R, Kapp ME, Fogo AB, Huo Y. Instance segmentation for whole slide imaging: end-to-end or detect-then-segment. J Med Imaging (Bellingham) [print-electronic]. 2021 Jan; 8(1): 14001. PMID: 33426152, PMCID: PMC7790159, PII: 20175R, DOI: 10.1117/1.JMI.8.1.014001, ISSN: 2329-4302.

Su H, Yang M, Wan C, Yi LX, Tang F, Zhu HY, Yi F, Yang HC, Fogo AB, Nie X, Zhang C. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney Int [print-electronic]. 2020 Jul; 98(1): 219-27. PMID: 32327202, PMCID: PMC7194105, PII: S0085-2538(20)30369-0, DOI: 10.1016/j.kint.2020.04.003, ISSN: 1523-1755.

Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. Tubular ß-catenin and FoxO3 interactions protect in chronic kidney disease. JCI Insight. 2020 May 5/21/2020; 5(10): PMID: 32369448, PMCID: PMC7259539, PII: 135454, DOI: 10.1172/jci.insight.135454, ISSN: 2379-3708.

Skrypnyk NI, Gist KM, Okamura K, Montford JR, You Z, Yang H, Moldovan R, Bodoni E, Blaine JT, Edelstein CL, Soranno DE, Kirkbride-Romeo LA, Griffin BR, Altmann C, Faubel S. IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury. Kidney Int [print-electronic]. 2020 May; 97(5): 966-79. PMID: 32081304, PMCID: PMC8409721, PII: S0085-2538(19)31154-8, DOI: 10.1016/j.kint.2019.11.013, ISSN: 1523-1755.

Yang H, Deng R, Lu Y, Zhu Z, Chen Y, Roland JT, Lu L, Landman BA, Fogo AB, Huo Y. CircleNet: Anchor-free Glomerulus Detection with Circle Representation. Med Image Comput Comput Assist Interv [print-electronic]. 2020; 2020: 35-44. PMID: 34414404, PMCID: PMC8372751, DOI: 10.1007/978-3-030-59719-1_4.

Yao L, Wright MF, Farmer BC, Peterson LS, Khan AM, Zhong J, Gewin L, Hao CM, Yang HC, Fogo AB. Fibroblast-specific plasminogen activator inhibitor-1 depletion ameliorates renal interstitial fibrosis after unilateral ureteral obstruction. Nephrol Dial Transplant. 2019 Dec 12/1/2019; 34(12): 2042-50. PMID: 31071225, PMCID: PMC6887698, PII: 5443269, DOI: 10.1093/ndt/gfz050, ISSN: 1460-2385.

Clark AJ, Yang H, Kon V. Urinary apoAl: novel marker of renal disease? [letter]. Pediatr Nephrol [print-electronic]. 2019 Nov; 34(11): 2425-6. PMID: 31402404, PMCID: PMC6801088, PII: 10.1007/s00467-019-04328-1, DOI: 10.1007/s00467-019-04328-1, ISSN: 1432-198X.

Clark AJ, Jabs K, Hunley TE, Jones DP, VanDeVoorde RG, Anderson C, Du L, Zhong J, Fogo AB, Yang H, Kon V. Urinary apolipoprotein AI in children with kidney disease. Pediatr Nephrol [print-electronic]. 2019 Nov; 34(11): 2351-60. PMID: 31230128, PMCID: PMC6801060, PII: 10.1007/s00467-019-04289-5, DOI: 10.1007/s00467-019-04289-5, ISSN: 1432-198X.

Menshikh A, Scarfe L, Delgado R, Finney C, Zhu Y, Yang H, de Caestecker MP. Capillary rarefaction is more closely associated with CKD progression after cisplatin, rhabdomyolysis, and ischemia-reperfusion-induced AKI than renal fibrosis. Am J Physiol Renal Physiol [print-electronic]. 2019 Nov 11/1/2019; 317(5): F1383-F1397-F1397. PMID: 31509009, PMCID: PMC6879932, DOI: 10.1152/ajprenal.00366.2019, ISSN: 1522-1466.

Zhong J, Yang H, Kon V. Kidney as modulator and target of "good/bad" HDL. Pediatr Nephrol [print-electronic]. 2019 Oct; 34(10): 1683-95. PMID: 30291429, PMCID: PMC6450786, PII: 10.1007/s00467-018-4104-2, DOI: 10.1007/s00467-018-4104-2, ISSN: 1432-198X.

Shaver CM, Paul MG, Putz ND, Landstreet SR, Kuck JL, Scarfe L, Skrypnyk N, Yang H, Harrison FE, de Caestecker MP, Bastarache JA, Ware LB. Cell-free hemoglobin augments acute kidney injury during experimental sepsis. Am J Physiol Renal Physiol [print-electronic]. 2019 Oct 10/1/2019; 317(4): F922-F929-F929. PMID: 31364379, PMCID: PMC6843044, DOI: 10.1152/ajprenal.00375.2018, ISSN: 1522-1466.

Zhang MZ, Sasaki K, Li Y, Li Z, Pan Y, Jin GN, Wang Y, Niu A, Wang S, Fan X, Chen JC, Borza C, Yang H, Pozzi A, Fogo AB, Harris RC. The Role of the EGF Receptor in Sex Differences in Kidney Injury. J Am Soc Nephrol [print-electronic]. 2019 Sep; 30(9): 1659-73. PMID: 31292196, PMCID: PMC6727256, PII: ASN.2018121244, DOI: 10.1681/ASN.2018121244, ISSN: 1533-3450.

Zhong J, Whitman JB, Yang HC, Fogo AB. Mechanisms of Scarring in Focal Segmental Glomerulosclerosis. J Histochem Cytochem [print-electronic]. 2019 Sep; 67(9): 623-32. PMID: 31116068, PMCID: PMC6713971, DOI: 10.1369/0022155419850170, ISSN: 1551-5044.

Tsuchida Y, Zhong J, Otsuka T, Dikalova A, Pastan I, Anantharamaiah GM, Linton MF, Yancey PG, Ikizler TA, Fogo AB, Yang H, Kon V. Lipoprotein modulation of proteinuric renal injury. Lab Invest [print-electronic]. 2019 Jul; 99(8): 1107-16. PMID: 31019291, PMCID: PMC6658349, PII: S0023-6837(22)00691-2, DOI: 10.1038/s41374-019-0253-6, ISSN: 1530-0307.

Soranno DE, Gil HW, Kirkbride-Romeo L, Altmann C, Montford JR, Yang H, Levine A, Buchanan J, Faubel S. Matching Human Unilateral AKI, a Reverse Translational Approach to Investigate Kidney Recovery after Ischemia. J Am Soc Nephrol [print-electronic]. 2019 Jun; 30(6): 990-1005. PMID: 31072827, PMCID: PMC6551779, PII: ASN.2018080808, DOI: 10.1681/ASN.2018080808, ISSN: 1533-3450.

Nickel NP, de Jesus Perez VA, Zamanian RT, Fessel JP, Cogan JD, Hamid R, West JD, de Caestecker MP, Yang H, Austin ED. Low-grade albuminuria in pulmonary arterial hypertension. Pulm Circ. 2019; 9(2): 2045894018824564. PMID: 30632900, PMCID: PMC6557031, DOI: 10.1177/2045894018824564, ISSN: 2045-8932.

Wang J, Zhong J, Yang HC, Fogo AB. Cross Talk from Tubules to Glomeruli. Toxicol Pathol [print-electronic]. 2018 Dec; 46(8): 944-8. PMID: 30157700, PMCID: PMC6693660, DOI: 10.1177/0192623318796784, ISSN: 1533-1601.

Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG. ASK1 contributes to fibrosis and dysfunction in models of kidney disease. J Clin Invest [print-electronic]. 2018 Oct 10/1/2018; 128(10): 4485-500. PMID: 30024858, PMCID: PMC6159961, PII: 99768, DOI: 10.1172/JCI99768, ISSN: 1558-8238.

Kaseda R, Tsuchida Y, Gamboa JL, Zhong J, Zhang L, Yang H, Dikalova A, Bian A, Davies S, Fogo AF, Linton MF, Brown NJ, Ikizler TA, Kon V. Angiotensin receptor blocker vs ACE inhibitor effects on HDL functionality in patients on maintenance hemodialysis. Nutr Metab Cardiovasc Dis [print-electronic]. 2018 Jun; 28(6): 582-91. PMID: 29691148, PMCID: PMC5959764, PII: S0939-4753(18)30090-5, DOI: 10.1016/j.numecd.2018.02.020, ISSN: 1590-3729.

Kaseda R, Tsuchida Y, Yang HC, Yancey PG, Zhong J, Tao H, Bian A, Fogo AB, Linton MRF, Fazio S, Ikizler TA, Kon V. Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism. BMC Nephrol. 2018 Jan 1/27/2018; 19(1): 17. PMID: 29374468, PMCID: PMC5787279, PII: 10.1186/s12882-018-0814-8, DOI: 10.1186/s12882-018-0814-8, ISSN: 1471-2369.

Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS. Blocking TGF-ß and ß-Catenin Epithelial Crosstalk Exacerbates CKD. J Am Soc Nephrol [print-electronic]. 2017 Dec; 28(12): 3490-503. PMID: 28701516, PMCID: PMC5698068, PII: ASN.2016121351, DOI: 10.1681/ASN.2016121351, ISSN: 1533-3450.

Lim BJ, Yang JW, Zou J, Zhong J, Matsusaka T, Pastan I, Zhang MZ, Harris RC, Yang HC, Fogo AB. Tubulointerstitial fibrosis can sensitize the kidney to subsequent glomerular injury. Kidney Int [print-electronic]. 2017 Dec; 92(6): 1395-403. PMID: 28709637, PMCID: PMC5696028, PII: S0085-2538(17)30283-1, DOI: 10.1016/j.kint.2017.04.010, ISSN: 1523-1755.

Zhang MZ, Wang X, Yang H, Fogo AB, Murphy BJ, Kaltenbach R, Cheng P, Zinker B, Harris RC. Lysophosphatidic Acid Receptor Antagonism Protects against Diabetic Nephropathy in a Type 2 Diabetic Model. J Am Soc Nephrol [print-electronic]. 2017 Nov; 28(11): 3300-11. PMID: 28739650, PMCID: PMC5661289, PII: ASN.2017010107, DOI: 10.1681/ASN.2017010107, ISSN: 1533-3450.

Zhong J, Yang HC, Fogo AB. A perspective on chronic kidney disease progression. Am J Physiol Renal Physiol [print-electronic]. 2017 Mar 3/1/2017; 312(3): F375-F384-F384. PMID: 27974318, PMCID: PMC5374308, PII: ajprenal.00266.2016, DOI: 10.1152/ajprenal.00266.2016, ISSN: 1522-1466.

Hunt R, Yalamanoglu A, Tumlin J, Schiller T, Baek JH, Wu A, Fogo AB, Yang H, Wong E, Miller P, Buehler PW, Kimchi-Sarfaty C. A mechanistic investigation of thrombotic microangiopathy associated with IV abuse of Opana ER. Blood [print-electronic]. 2017 Feb 2/16/2017; 129(7): 896-905. PMID: 27864296, PMCID: PMC5314814, PII: S0006-4971(20)33694-6, DOI: 10.1182/blood-2016-08-736579, ISSN: 1528-0020.

Wang X, Yao B, Wang Y, Fan X, Wang S, Niu A, Yang H, Fogo A, Zhang MZ, Harris RC. Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy. Diabetes [print-electronic]. 2017 Feb; 66(2): 494-504. PMID: 27815317, PMCID: PMC5248989, PII: db16-0773, DOI: 10.2337/db16-0773, ISSN: 1939-327X.

Skrypnyk NI, Voziyan P, Yang H, de Caestecker CR, Theberge MC, Drouin M, Hudson B, Harris RC, de Caestecker MP. Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. Am. J. Physiol. Renal Physiol [print-electronic]. 2016 Aug 8/1/2016; 311(2): F268-77. PMID: 27194713, PMCID: PMC5008672, PII: ajprenal.00056.2016, DOI: 10.1152/ajprenal.00056.2016, ISSN: 1522-1466.

Matsushita K, Yang HC, Mysore MM, Zhong J, Shyr Y, Ma LJ, Fogo AB. Effects of combination PPAR¿ agonist and angiotensin receptor blocker on glomerulosclerosis. Lab. Invest [print-electronic]. 2016 Jun; 96(6): 602-9. PMID: 26999660, PII: labinvest201642, DOI: 10.1038/labinvest.2016.42, ISSN: 1530-0307.

Yang H, Fogo AB, Kon V. Kidneys: key modulators of high-density lipoprotein levels and function. Curr. Opin. Nephrol. Hypertens. 2016 May; 25(3): 174-9. PMID: 27008596, PMCID: PMC4899840, DOI: 10.1097/MNH.0000000000000217, ISSN: 1473-6543.

Chiba T, Skrypnyk NI, Skvarca LB, Penchev R, Zhang KX, Rochon ER, Fall JL, Paueksakon P, Yang H, Alford CE, Roman BL, Zhang MZ, Harris R, Hukriede NA, de Caestecker MP. Retinoic Acid Signaling Coordinates Macrophage-Dependent Injury and Repair after AKI. J. Am. Soc. Nephrol [print-electronic]. 2016 Feb; 27(2): 495-508. PMID: 26109319, PMCID: PMC4731115, PII: ASN.2014111108, DOI: 10.1681/ASN.2014111108, ISSN: 1533-3450.

Qian HS, Weldon SM, Matera D, Lee C, Yang H, Fryer RM, Fogo AB, Reinhart GA. Quantification and Comparison of Anti-Fibrotic Therapies by Polarized SRM and SHG-Based Morphometry in Rat UUO Model. PLoS ONE. 2016; 11(6): e0156734. PMID: 27257917, PMCID: PMC4892485, PII: PONE-D-15-48960, DOI: 10.1371/journal.pone.0156734, ISSN: 1932-6203.

Yamamoto S, Zhong J, Yancey PG, Zuo Y, Linton MF, Fazio S, Yang H, Narita I, Kon V. Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype. Atherosclerosis [print-electronic]. 2015 Sep; 242(1): 56-64. PMID: 26184694, PMCID: PMC4850906, PII: S0021-9150(15)30016-2, DOI: 10.1016/j.atherosclerosis.2015.06.055, ISSN: 1879-1484.

Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L. Renal fibrosis is not reduced by blocking transforming growth factor-ß signaling in matrix-producing interstitial cells. Kidney Int [print-electronic]. 2015 Sep; 88(3): 503-14. PMID: 25760325, PMCID: PMC4556568, PII: S2157-1716(15)32233-4, DOI: 10.1038/ki.2015.51, ISSN: 1523-1755.

Kon V, Yang H, Fazio S. Residual Cardiovascular Risk in Chronic Kidney Disease: Role of High-density Lipoprotein. Arch. Med. Res [print-electronic]. 2015 Jul; 46(5): 379-91. PMID: 26009251, PMCID: PMC4805367, PII: S0188-4409(15)00129-0, DOI: 10.1016/j.arcmed.2015.05.009, ISSN: 1873-5487.

Yang HC, Fogo AB. Fibrosis and renal aging. Kidney Int Suppl (2011). 2014 Nov; 4(1): 75-8. PMID: 26312154, PMCID: PMC4536965, PII: S2157-1716(15)31196-5, DOI: 10.1038/kisup.2014.14, ISSN: 2157-1724.

Yang HC, Fogo AB. Mechanisms of disease reversal in focal and segmental glomerulosclerosis. Adv Chronic Kidney Dis. 2014 Sep; 21(5): 442-7. PMID: 25168834, PMCID: PMC4151242, PII: S1548-5595(14)00076-7, DOI: 10.1053/j.ackd.2014.04.001, ISSN: 1548-5609.

Zhong J, Yang HC, Kon V, Fogo AB, Lawrence DA, Ma J. Vitronectin-binding PAI-1 protects against the development of cardiac fibrosis through interaction with fibroblasts. Lab. Invest [print-electronic]. 2014 Jun; 94(6): 633-44. PMID: 24687120, PMCID: PMC4361016, PII: labinvest201451, DOI: 10.1038/labinvest.2014.51, ISSN: 1530-0307.

Lim BJ, Yang HC, Fogo AB. Animal models of regression/progression of kidney disease. Drug Discov Today Dis Models. 2014; 11: 45-51. PMID: 25722733, PMCID: PMC4337226, DOI: 10.1016/j.ddmod.2014.06.003, ISSN: 1740-6757.

Yang HC, Liu SJ, Fogo AB. Kidney regeneration in mammals. Nephron Exp. Nephrol [print-electronic]. 2014; 126(2): 50. PMID: 24854640, PMCID: PMC4337834, PII: 000360661, DOI: 10.1159/000360661, ISSN: 1660-2129.

Miyazawa T, Zeng F, Wang S, Fan X, Cheng H, Yang H, Bian A, Fogo AB, Harris RC. Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression. Kidney Int [print-electronic]. 2013 Dec; 84(6): 1176-88. PMID: 23760291, PMCID: PMC3796048, PII: S0085-2538(15)56105-X, DOI: 10.1038/ki.2013.214, ISSN: 1523-1755.

Zuo Y, Chun B, Potthoff SA, Kazi N, Brolin TJ, Orhan D, Yang HC, Ma LJ, Kon V, Myöhänen T, Rhaleb NE, Carretero OA, Fogo AB. Thymosin ß4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int [print-electronic]. 2013 Dec; 84(6): 1166-75. PMID: 23739235, PMCID: PMC3830708, PII: S0085-2538(15)56103-6, DOI: 10.1038/ki.2013.209, ISSN: 1523-1755.

Fatima H, Moeller MJ, Smeets B, Yang HC, D'Agati VD, Alpers CE, Fogo AB. Parietal epithelial cell activation marker in early recurrence of FSGS in the transplant. Clin J Am Soc Nephrol [print-electronic]. 2012 Nov; 7(11): 1852-8. PMID: 22917699, PMCID: PMC3488951, PII: CJN.10571011, DOI: 10.2215/CJN.10571011, ISSN: 1555-905X.

Howard C, Tao S, Yang HC, Fogo AB, Woodgett JR, Harris RC, Rao R. Specific deletion of glycogen synthase kinase-3ß in the renal proximal tubule protects against acute nephrotoxic injury in mice. Kidney Int [print-electronic]. 2012 Nov; 82(9): 1000-9. PMID: 22785175, PMCID: PMC3472082, PII: S0085-2538(15)55668-8, DOI: 10.1038/ki.2012.239, ISSN: 1523-1755.

Zhang MZ, Yao B, Yang S, Yang H, Wang S, Fan X, Yin H, Fogo AB, Moeckel GW, Harris RC. Intrarenal dopamine inhibits progression of diabetic nephropathy. Diabetes [print-electronic]. 2012 Oct; 61(10): 2575-84. PMID: 22688335, PMCID: PMC3447896, PII: db12-0046, DOI: 10.2337/db12-0046, ISSN: 1939-327X.

Zuo Y, Yang HC, Potthoff SA, Najafian B, Kon V, Ma LJ, Fogo AB. Protective effects of PPAR¿ agonist in acute nephrotic syndrome. Nephrol. Dial. Transplant [print-electronic]. 2012 Jan; 27(1): 174-81. PMID: 21565943, PMCID: PMC3276311, PII: gfr240, DOI: 10.1093/ndt/gfr240, ISSN: 1460-2385.

Yang HC, Rossini M, Ma LJ, Zuo Y, Ma J, Fogo AB. Cells derived from young bone marrow alleviate renal aging. J. Am. Soc. Nephrol [print-electronic]. 2011 Nov; 22(11): 2028-36. PMID: 21965376, PMCID: PMC3231782, PII: ASN.2010090982, DOI: 10.1681/ASN.2010090982, ISSN: 1533-3450.

Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC. Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J. Clin. Invest [print-electronic]. 2011 Jul; 121(7): 2845-54. PMID: 21701066, PMCID: PMC3223841, PII: 57324, DOI: 10.1172/JCI57324, ISSN: 1558-8238.

Ma J, Matsusaka T, Yang HC, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I. Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside. Pediatr. Res. 2011 Jul; 70(1): 83-9. PMID: 21451433, PMCID: PMC3113658, DOI: 10.1203/PDR.0b013e31821bdf1c, ISSN: 1530-0447.

Ma LJ, Corsa BA, Zhou J, Yang H, Li H, Tang YW, Babaev VR, Major AS, Linton MF, Fazio S, Hunley TE, Kon V, Fogo AB. Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity. Am. J. Physiol. Renal Physiol [print-electronic]. 2011 May; 300(5): F1203-13. PMID: 21367915, PMCID: PMC3094053, PII: ajprenal.00468.2010, DOI: 10.1152/ajprenal.00468.2010, ISSN: 1522-1466.

Yang H, Fogo AB. Cell senescence in the aging kidney. J. Am. Soc. Nephrol [print-electronic]. 2010 Sep; 21(9): 1436-9. PMID: 20705707, PII: ASN.2010020205, DOI: 10.1681/ASN.2010020205, ISSN: 1533-3450.

Rossini M, Naito T, Yang H, Freeman M, Donnert E, Ma LJ, Dunn SR, Sharma K, Fogo AB. Sulodexide ameliorates early but not late kidney disease in models of radiation nephropathy and diabetic nephropathy. Nephrol. Dial. Transplant [print-electronic]. 2010 Jun; 25(6): 1803-10. PMID: 20061322, PMCID: PMC2902889, PII: gfp724, DOI: 10.1093/ndt/gfp724, ISSN: 1460-2385.

He W, Wang Y, Zhang MZ, You L, Davis LS, Fan H, Yang HC, Fogo AB, Zent R, Harris RC, Breyer MD, Hao CM. Sirt1 activation protects the mouse renal medulla from oxidative injury. J. Clin. Invest [print-electronic]. 2010 Apr; 120(4): 1056-68. PMID: 20335659, PMCID: PMC2846063, PII: 41563, DOI: 10.1172/JCI41563, ISSN: 1558-8238.

Naito T, Ma LJ, Yang H, Zuo Y, Tang Y, Han JY, Kon V, Fogo AB. Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis. Am. J. Physiol. Renal Physiol [print-electronic]. 2010 Mar; 298(3): F683-91. PMID: 20042458, PMCID: PMC2838584, PII: 00503.2009, DOI: 10.1152/ajprenal.00503.2009, ISSN: 1522-1466.

Yang HC, Zuo Y, Fogo AB. Models of chronic kidney disease. Drug Discov Today Dis Models. 2010; 7(1-2): 13-9. PMID: 21286234, PMCID: PMC3030258, DOI: 10.1016/j.ddmod.2010.08.002, ISSN: 1740-6757.

Giannico G, Yang H, Neilson EG, Fogo AB. Dystroglycan in the diagnosis of FSGS. Clin J Am Soc Nephrol [print-electronic]. 2009 Nov; 4(11): 1747-53. PMID: 19808230, PMCID: PMC2774958, PII: CJN.01510209, DOI: 10.2215/CJN.01510209, ISSN: 1555-905X.

Yang HC, Deleuze S, Zuo Y, Potthoff SA, Ma LJ, Fogo AB. The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury. J. Am. Soc. Nephrol [print-electronic]. 2009 Nov; 20(11): 2380-8. PMID: 19797472, PMCID: PMC2799181, PII: ASN.2008111138, DOI: 10.1681/ASN.2008111138, ISSN: 1533-3450.

Ma J, Rossini M, Yang HC, Zuo Y, Fogo AB, Ichikawa I. Effects of podocyte injury on glomerular development. Pediatr. Res. 2007 Oct; 62(4): 417-21. PMID: 17667850, PII: 00006450-200710000-00007, DOI: 10.1203/PDR.0b013e31813cbed1, ISSN: 0031-3998.

Yang HC, Ma LJ, Ma J, Fogo AB. Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis. Kidney Int. 2006 May; 69(10): 1756-64. PMID: 16598202, PII: S0085-2538(15)51354-9, DOI: 10.1038/sj.ki.5000336, ISSN: 0085-2538.

Ma LJ, Nakamura S, Aldigier JC, Rossini M, Yang H, Liang X, Nakamura I, Marcantoni C, Fogo AB. Regression of glomerulosclerosis with high-dose angiotensin inhibition is linked to decreased plasminogen activator inhibitor-1. J. Am. Soc. Nephrol [print-electronic]. 2005 Apr; 16(4): 966-76. PMID: 15728787, PII: ASN.2004060492, DOI: 10.1681/ASN.2004060492, ISSN: 1046-6673.

Ma J, Matsusaka T, Yang H, Kawachi H, Shimizu F, Isaka Y, Imai E, Kon V, Ichikawa I. Local actions of endogenous angiotensin II in injured glomeruli. J. Am. Soc. Nephrol. 2004 May; 15(5): 1268-76. PMID: 15100367, ISSN: 1046-6673.

Ma LJ, Yang H, Gaspert A, Carlesso G, Barty MM, Davidson JM, Sheppard D, Fogo AB. Transforming growth factor-beta-dependent and -independent pathways of induction of tubulointerstitial fibrosis in beta6(-/-) mice. Am. J. Pathol. 2003 Oct; 163(4): 1261-73. PMID: 14507636, PMCID: PMC1868298, PII: S0002-9440(10)63486-4, ISSN: 0002-9440.