Vadim K. Pedchenko, Ph.D.

Research Associate Professor

vadim.pedchenko@vanderbilt.edu
Faculty Appointments
Research Associate Professor of Medicine
Education
Ph.D., Palladin Institute of Biochemistry, Kiev, UkraineM.S., Kiev State University, Kiev, UkraineB.S., Kiev State University, Kiev, Ukraine
Office Address
B-3115 MCN
1161 21st Ave South
Nashville, TN 37232-2372
Publications
Fidler AL, Darris CE, Chetyrkin SV, Pedchenko VK, Boudko SP, Brown KL, Gray Jerome W, Hudson JK, Rokas A, Hudson BG. Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues. Elife. 2017 Apr 4/18/2017; 6: PMID: 28418331, PMCID: PMC5395295, DOI: 10.7554/eLife.24176, ISSN: 2050-084X.

Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT, , Hudson JK, Hudson BG. A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2014 Jan 1/7/2014; 111(1): 331-6. PMID: 24344311, PMCID: PMC3890831, PII: 1318499111, DOI: 10.1073/pnas.1318499111, ISSN: 1091-6490.

Pedchenko VK, Chetyrkin SV, Chuang P, Ham AJ, Saleem MA, Mathieson PW, Hudson BG, Voziyan PA. Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Diabetes. 2005 Oct; 54(10): 2952-60. PMID: 16186398, PII: 54/10/2952, ISSN: 0012-1797.

Imagawa W, Pedchenko VK, Helber J, Zhang H. Hormone/growth factor interactions mediating epithelial/stromal communication in mammary gland development and carcinogenesis. J. Steroid Biochem. Mol. Biol. 2002 Feb; 80(2): 213-30. PMID: 11897505, PII: S0960076001001881, ISSN: 0960-0760.

Imagawa W, Pedchenko VK. In vivo inhibition of keratinocyte growth factor receptor expression by estrogen and antagonism by progesterone in the mouse mammary gland. J. Endocrinol. 2001 Nov; 171(2): 319-27. PMID: 11691652, PII: JOE04146, ISSN: 0022-0795.

Pedchenko VK, Imagawa W. Pattern of expression of the KGF receptor and its ligands KGF and FGF-10 during postnatal mouse mammary gland development. Mol. Reprod. Dev. 2000 Aug; 56(4): 441-7. PMID: 10911393, PII: 10.1002/1098-2795(200008)56:4<441::AID-MRD1>3.0.CO;2-C, DOI: 10.1002/1098-2795(200008)56:4<441::AID-MRD1>3.0.CO;2-C, ISSN: 1040-452X.

Imagawa W, Pedchenko VK, Helber J, Xing C. Attenuation and loss of hormonal modulation of KGF (FGF-7)/KGF receptor expression and mitogenesis during mammary tumor progression. J. Cell. Physiol. 2000 Aug; 184(2): 222-8. PMID: 10867647, PII: 10.1002/1097-4652(200008)184:2<222::AID-JCP10>3.0.CO;2-6, DOI: 10.1002/1097-4652(200008)184:2<222::AID-JCP10>3.0.CO;2-6, ISSN: 0021-9541.

Pedchenko VK, Imagawa W. Estrogen treatment in vivo increases keratinocyte growth factor expression in the mammary gland. J. Endocrinol. 2000 Apr; 165(1): 39-49. PMID: 10750034, PII: JOE03558, ISSN: 0022-0795.

Pedchenko VK, Imagawa WT. Mammogenic hormones differentially modulate keratinocyte growth factor (KGF)-induced proliferation and KGF receptor expression in cultured mouse mammary gland epithelium. Endocrinology. 1998 May; 139(5): 2519-26. PMID: 9564867, DOI: 10.1210/endo.139.5.6007, ISSN: 0013-7227.

Pedchenko VK, Nasirova GF, Palladina TA. Lysophosphatidylcholine specifically stimulates plasma membrane H(+)-ATPase from corn roots. FEBS Lett. 1990 Nov 11/26/1990; 275(1-2): 205-8. PMID: 2148158, PII: 0014-5793(90)81472-Z, ISSN: 0014-5793.