Joern-Hendrik Weitkamp, M.D.

Faculty Appointments
Professor of Pediatrics
M.D., Medicine, Universität Ulm, Ulm, Germany
Office Address
Childrens Way
Nashville, TN 37232
Research Description
The focus of my research and scholarly work has been in neonatal immunology, neonatal infectious disease and necrotizing enterocolitis. I am specifically interested in the prenatal influences on the developing immune system. We use human tissue, blood and saliva samples to discover the microbial, metabolomic and immunological profiles and mechanisms of prematurity and its complications.

As the Director for Patient-Oriented Research, I oversee numerous clinical trials and translational studies in neonatology. Topics include immunological mechanisms of neurodevelopmental decline in MECP2 deletion syndrome, infectious causes of chronic lung disease, optimizing antimicrobial treatment in neonates, development of non-invasive diagnostics, aerolized surfactant, erythropoetin for brain protection and others.
Clinical Description
Attending Physician in the Division of Neonatology, DepartMonroe Carell Jr. Children’s Hospital at Vanderbilt. Supervise care of critically ill newborns inborn at the 100-bed level IV NICU or transported from referring hospitals throughout the states of Tennessee, Kentucky and Alabama. Physician Leader, Vanderbilt NICU Choosing Wisely Antimicrobial Stewardship Committee since 2015.
Research Keywords
Mucosal immune development; necrotizing enterocolitis (NEC); microbiome; immunology; infectious disease; sepsis, pharmacology, neonatology
Clinical Research Keywords
Neonatal infectious diseases, sepsis marker, health-care associated infections, quality improvement
Mara MA, Good M, Weitkamp JH. Innate and adaptive immunity in necrotizing enterocolitis. Semin Fetal Neonatal Med [print-electronic]. 2018 Dec; 23(6): 394-9. PMID: 30146477, PMCID: PMC6269198, PII: S1744-165X(18)30094-5, DOI: 10.1016/j.siny.2018.08.002, ISSN: 1878-0946.

Gopal SH, Edwards KM, Creech B, Weitkamp JH. Variability in Immunization Practices for Preterm Infants. Am J Perinatol [print-electronic]. 2018 Dec; 35(14): 1394-8. PMID: 29883982, DOI: 10.1055/s-0038-1660453, ISSN: 1098-8785.

Garinis AC, Kemph A, Tharpe AM, Weitkamp JH, McEvoy C, Steyger PS. Monitoring neonates for ototoxicity. Int J Audiol [print-electronic]. 2018 Sep; 57(sup4): S41-S48. PMID: 28949262, PMCID: PMC5741535, DOI: 10.1080/14992027.2017.1339130, ISSN: 1708-8186.

Collins A, Weitkamp JH, Wynn JL. Why are preterm newborns at increased risk of infection?. Arch. Dis. Child. Fetal Neonatal Ed [print-electronic]. 2018 Jul; 103(4): F391-F394. PMID: 29382648, PMCID: PMC6013388, PII: archdischild-2017-313595, DOI: 10.1136/archdischild-2017-313595, ISSN: 1468-2052.

Ackerman DL, Craft KM, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD. Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii. ACS Infect Dis [print-electronic]. 2018 Mar 3/9/2018; 4(3): 315-24. PMID: 29198102, PMCID: PMC6019282, DOI: 10.1021/acsinfecdis.7b00183, ISSN: 2373-8227.

Grossarth SN, Coggins SA, Tune A, Ariagno RL, Fanaroff AA, Weitkamp JH. The Marshall Klaus Research Award and Tribute to a Trailblazing Neonatologist. J Perinatol [print-electronic]. 2018 Mar; 38(3): 211-6. PMID: 29234145, PII: 10.1038/s41372-017-0004-8, DOI: 10.1038/s41372-017-0004-8, ISSN: 1476-5543.

Romano-Keeler J, Shilts MH, Tovchigrechko A, Wang C, Brucker RM, Moore DJ, Fonnesbeck C, Meng S, Correa H, Lovvorn HN, Tang YW, Hooper L, Bordenstein SR, Das SR, Weitkamp JH. Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure. PLoS ONE. 2018; 13(10): e0206366. PMID: 30365522, PMCID: PMC6203398, PII: PONE-D-18-22175, DOI: 10.1371/journal.pone.0206366, ISSN: 1932-6203.

Martinez KA, Romano-Keeler J, Zackular JP, Moore DJ, Brucker RM, Hooper C, Meng S, Brown N, Mallal S, Reese J, Aronoff DM, Shin H, Dominguez-Bello MG, Weitkamp JH. Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice. PLoS ONE. 2018; 13(5): e0197439. PMID: 29771989, PMCID: PMC5957394, PII: PONE-D-17-43953, DOI: 10.1371/journal.pone.0197439, ISSN: 1932-6203.

Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp JH. In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4+ T Lymphocytes. J. Immunol [print-electronic]. 2017 Nov 11/1/2017; 199(9): 3074-85. PMID: 28947540, PMCID: PMC5659751, PII: jimmunol.1601880, DOI: 10.4049/jimmunol.1601880, ISSN: 1550-6606.

Ackerman DL, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD. Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus. ACS Infect Dis [print-electronic]. 2017 Aug 8/11/2017; 3(8): 595-605. PMID: 28570820, PMCID: PMC5868341, DOI: 10.1021/acsinfecdis.7b00064, ISSN: 2373-8227.

Riemenschneider K, Redenius R, Reese J, Fine JD, Weitkamp JH, Tkaczyk E. Erythematous plaques and papules on a premature infant. J. Am. Acad. Dermatol. 2017 Apr; 76(4): e111-e112. PMID: 29081565, PMCID: PMC5563474, PII: S0190-9622(16)30725-3, DOI: 10.1016/j.jaad.2016.08.038, ISSN: 1097-6787.

Kaufman DA, Coggins SA, Zanelli SA, Weitkamp JH. Congenital Cutaneous Candidiasis: Prompt Systemic Treatment is Associated with Improved Outcomes in Neonates. Clin. Infect. Dis [print-electronic]. 2017 Feb 2/4/2017; PMID: 28158439, PII: 2967977, DOI: 10.1093/cid/cix119, ISSN: 1537-6591.

Robinson JR, Rellinger EJ, Hatch LD, Weitkamp JH, Speck KE, Danko M, Blakely ML. Surgical necrotizing enterocolitis. Semin. Perinatol [print-electronic]. 2017 Feb; 41(1): 70-9. PMID: 27836422, PII: S0146-0005(16)30096-9, DOI: 10.1053/j.semperi.2016.09.020, ISSN: 1558-075X.

Romano-Keeler J, Azcarate-Peril MA, Weitkamp JH, Slaughter JC, McDonald WH, Meng S, Latuga MS, Wynn JL. Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu. J Perinatol [print-electronic]. 2017 Jan; 37(1): 36-41. PMID: 27684425, PMCID: PMC5215726, PII: jp2016161, DOI: 10.1038/jp.2016.161, ISSN: 1476-5543.

Coggins SA, Weitkamp JH, Grunwald L, Stark AR, Reese J, Walsh W, Wynn JL. Heart rate characteristic index monitoring for bloodstream infection in an NICU: a 3-year experience. Arch. Dis. Child. Fetal Neonatal Ed [print-electronic]. 2016 Jul; 101(4): F329-32. PMID: 26518312, PMCID: PMC4851911, PII: archdischild-2015-309210, DOI: 10.1136/archdischild-2015-309210, ISSN: 1468-2052.

Cohran V, Managlia E, Bradford EM, Goretsky T, Li T, Katzman RB, Cheresh P, Brown JB, Hawkins J, Liu SX, De Plaen IG, Weitkamp JH, Helmrath M, Zhang Z, Barrett TA. Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection. Am. J. Pathol [print-electronic]. 2016 Jul; 186(7): 1837-46. PMID: 27157990, PMCID: PMC4929398, PII: S0002-9440(16)30070-0, DOI: 10.1016/j.ajpath.2016.03.008, ISSN: 1525-2191.

Weitkamp JH, Guthrie SO, Wong HR, Moldawer LL, Baker HV, Wynn JL. Histological chorioamnionitis shapes the neonatal transcriptomic immune response. Early Hum. Dev [print-electronic]. 2016 Jul; 98: 1-6. PMID: 27318328, PMCID: PMC4947555, PII: S0378-3782(16)30230-4, DOI: 10.1016/j.earlhumdev.2016.06.001, ISSN: 1872-6232.

Maalouf FI, Coggins SA, Phillips JA, Stefanescu BM, Weitkamp JH. A newborn with severe skeletal dysplasia. Arch Dis Child Educ Pract Ed [print-electronic]. 2016 Jun; 101(3): 147. PMID: 26307691, PII: archdischild-2015-308719, DOI: 10.1136/archdischild-2015-308719, ISSN: 1743-0593.

Maalouf FI, Coggins SA, Phillips JA, Stefanescu BM, Weitkamp JH. Answers to Epilogue questions. Arch Dis Child Educ Pract Ed. 2016 Jun; 101(3): 168. PMID: 27194776, PII: archdischild-2015-308719a, DOI: 10.1136/archdischild-2015-308719a, ISSN: 1743-0593.

Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ. Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2016 May 5/10/2016; 113(19): E2627-35. PMID: 27114524, PMCID: PMC4868456, PII: 1515793113, DOI: 10.1073/pnas.1515793113, ISSN: 1091-6490.

Fung CM, White JR, Brown AS, Gong H, Weitkamp JH, Frey MR, McElroy SJ. Intrauterine Growth Restriction Alters Mouse Intestinal Architecture during Development. PLoS ONE. 2016; 11(1): e0146542. PMID: 26745886, PMCID: PMC4706418, PII: PONE-D-15-24400, DOI: 10.1371/journal.pone.0146542, ISSN: 1932-6203.

Scheuer T, Brockmöller V, Blanco Knowlton M, Weitkamp JH, Ruhwedel T, Mueller S, Endesfelder S, Bührer C, Schmitz T. Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline. Glia [print-electronic]. 2015 Oct; 63(10): 1825-39. PMID: 25964099, PMCID: PMC4534324, DOI: 10.1002/glia.22847, ISSN: 1098-1136.

Wynn JL, Scumpia PO, Stocks BT, Romano-Keeler J, Alrifai MW, Liu JH, Kim AS, Alford CE, Matta P, Weitkamp JH, Moore DJ. Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality. J. Immunol [print-electronic]. 2015 Aug 8/1/2015; 195(3): 1064-70. PMID: 26101326, PMCID: PMC4506905, PII: jimmunol.1500771, DOI: 10.4049/jimmunol.1500771, ISSN: 1550-6606.

Coggins SA, Wynn JL, Weitkamp JH. Infectious causes of necrotizing enterocolitis. Clin Perinatol [print-electronic]. 2015 Mar; 42(1): 133-54, ix. PMID: 25678001, PMCID: PMC4328138, PII: S0095-5108(14)00121-3, DOI: 10.1016/j.clp.2014.10.012, ISSN: 1557-9840.

Romano-Keeler J, Weitkamp JH. Maternal influences on fetal microbial colonization and immune development. Pediatr. Res [print-electronic]. 2015 Jan; 77(1-2): 189-95. PMID: 25310759, PMCID: PMC4289016, PII: pr2014163, DOI: 10.1038/pr.2014.163, ISSN: 1530-0447.

Van Kaer L, Algood HM, Singh K, Parekh VV, Greer MJ, Piazuelo MB, Weitkamp JH, Matta P, Chaturvedi R, Wilson KT, Olivares-Villagómez D. CD8aa¿ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity. Immunity [print-electronic]. 2014 Sep 9/18/2014; 41(3): 451-64. PMID: 25220211, PMCID: PMC4169715, PII: S1074-7613(14)00304-5, DOI: 10.1016/j.immuni.2014.08.010, ISSN: 1097-4180.

Huang TK, Reese J, Weitkamp JH, Stancombe BB. Congenital radiocontrast agent in the neonatal gut. J. Pediatr [print-electronic]. 2014 May; 164(5): 1236-1236.e1. PMID: 24534573, PII: S0022-3476(14)00025-0, DOI: 10.1016/j.jpeds.2014.01.019, ISSN: 1097-6833.

Romano-Keeler J, Moore DJ, Wang C, Brucker RM, Fonnesbeck C, Slaughter JC, Li H, Curran DP, Meng S, Correa H, Lovvorn HN, Tang YW, Bordenstein S, George AL, Weitkamp JH. Early life establishment of site-specific microbial communities in the gut. Gut Microbes [print-electronic]. 2014 Mar; 5(2): 192-201. PMID: 24637795, PMCID: PMC4063844, PII: 28442, DOI: 10.4161/gmic.28442, ISSN: 1949-0984.

Weitkamp JH, Rosen MJ, Zhao Z, Koyama T, Geem D, Denning TL, Rock MT, Moore DJ, Halpern MD, Matta P, Denning PW. Small intestinal intraepithelial TCR¿d+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis. PLoS ONE. 2014; 9(6): e99042. PMID: 24905458, PMCID: PMC4048281, PII: PONE-D-14-10885, DOI: 10.1371/journal.pone.0099042, ISSN: 1932-6203.

Casner M, Hoesli SJ, Slaughter JC, Hill M, Weitkamp JH. Incidence of catheter-related bloodstream infections in neonates following removal of peripherally inserted central venous catheters. Pediatr Crit Care Med. 2014 Jan; 15(1): 42-8. PMID: 24141656, DOI: 10.1097/PCC.0b013e31829f5feb, ISSN: 1529-7535.

Rosen MJ, Chaturvedi R, Washington MK, Kuhnhein LA, Moore PD, Coggeshall SS, McDonough EM, Weitkamp JH, Singh AB, Coburn LA, Williams CS, Yan F, Van Kaer L, Peebles RS, Wilson KT. STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. J. Immunol [print-electronic]. 2013 Feb 2/15/2013; 190(4): 1849-58. PMID: 23303670, PMCID: PMC3563924, PII: jimmunol.1201373, DOI: 10.4049/jimmunol.1201373, ISSN: 1550-6606.

Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB. Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios. Gut [print-electronic]. 2013 Jan; 62(1): 73-82. PMID: 22267598, PMCID: PMC3606820, PII: gutjnl-2011-301551, DOI: 10.1136/gutjnl-2011-301551, ISSN: 1468-3288.

Coggins SA, Wynn JL, Hill ML, Slaughter JC, Ozdas-Weitkamp A, Jalloh O, Waitman LR, Carnevale RJ, Weitkamp JH. Use of a computerized C-reactive protein (CRP) based sepsis evaluation in very low birth weight (VLBW) infants: a five-year experience. PLoS ONE. 2013; 8(11): e78602. PMID: 24244325, PMCID: PMC3823853, PII: PONE-D-13-17677, DOI: 10.1371/journal.pone.0078602, ISSN: 1932-6203.

MohanKumar K, Kaza N, Jagadeeswaran R, Garzon SA, Bansal A, Kurundkar AR, Namachivayam K, Remon JI, Bandepalli CR, Feng X, Weitkamp JH, Maheshwari A. Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: evidence from an animal model. Am. J. Physiol. Gastrointest. Liver Physiol [print-electronic]. 2012 Jul; 303(1): G93-102. PMID: 22538401, PMCID: PMC3404576, PII: ajpgi.00016.2012, DOI: 10.1152/ajpgi.00016.2012, ISSN: 1522-1547.

Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ. Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice. Dis Model Mech [print-electronic]. 2012 Jul; 5(4): 522-32. PMID: 22328592, PMCID: PMC3380715, PII: dmm.009001, DOI: 10.1242/dmm.009001, ISSN: 1754-8411.

Plosa EJ, Esbenshade JC, Fuller MP, Weitkamp JH. Cytomegalovirus infection. Pediatr Rev. 2012 Apr; 33(4): 156-63; quiz 163. PMID: 22474112, PII: 33/4/156, DOI: 10.1542/pir.33-4-156, ISSN: 1526-3347.

Romano-Keeler J, Weitkamp JH, Moore DJ. Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes. Curr Opin Endocrinol Diabetes Obes. 2012 Apr; 19(2): 73-80. PMID: 22357099, PMCID: PMC3560352, DOI: 10.1097/MED.0b013e3283514d43, ISSN: 1752-2978.

Ullrich T, Tang YW, Correa H, Garzon SA, Maheshwari A, Hill M, Matta P, Krishnan MK, Weitkamp JH. Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis. Pediatr. Infect. Dis. J. 2012 Apr; 31(4): 413-4. PMID: 22173144, PMCID: PMC3305842, DOI: 10.1097/INF.0b013e318242534a, ISSN: 1532-0987.

Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore DJ, Yoder SM, Rock MT, Jagasia M. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood [print-electronic]. 2012 Mar 3/8/2012; 119(10): 2417-21. PMID: 22262764, PMCID: PMC3311262, PII: blood-2011-10-384750, DOI: 10.1182/blood-2011-10-384750, ISSN: 1528-0020.

McElroy SJ, Hobbs S, Kallen M, Tejera N, Rosen MJ, Grishin A, Matta P, Schneider C, Upperman J, Ford H, Polk DB, Weitkamp JH. Transactivation of EGFR by LPS induces COX-2 expression in enterocytes. PLoS ONE [print-electronic]. 2012; 7(5): e38373. PMID: 22675459, PMCID: PMC3364993, PII: PONE-D-11-25419, DOI: 10.1371/journal.pone.0038373, ISSN: 1932-6203.

Schulert GS, Walsh WF, Weitkamp JH. Polymicrogyria and congenital parvovirus b19 infection. AJP Rep [print-electronic]. 2011 Dec; 1(2): 105-10. PMID: 23705097, PMCID: PMC3653533, PII: 01105, DOI: 10.1055/s-0031-1285984, ISSN: 2157-6998.

Smith PB, Cohen-Wolkowiez M, Castro LM, Poindexter B, Bidegain M, Weitkamp JH, Schelonka RL, Ward RM, Wade K, Valencia G, Burchfield D, Arrieta A, Bhatt-Mehta V, Walsh M, Kantak A, Rasmussen M, Sullivan JE, Finer N, Brozanski BS, Sanchez P, van den Anker J, Blumer J, Kearns GL, Capparelli EV, Anand R, Benjamin DK, . Population pharmacokinetics of meropenem in plasma and cerebrospinal fluid of infants with suspected or complicated intra-abdominal infections. Pediatr. Infect. Dis. J. 2011 Oct; 30(10): 844-9. PMID: 21829139, PMCID: PMC3173561, DOI: 10.1097/INF.0b013e31822e8b0b, ISSN: 1532-0987.

McElroy SJ, Prince LS, Weitkamp JH, Reese J, Slaughter JC, Polk DB. Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis. Am. J. Physiol. Gastrointest. Liver Physiol [print-electronic]. 2011 Oct; 301(4): G656-66. PMID: 21737776, PMCID: PMC3191555, PII: ajpgi.00550.2010, DOI: 10.1152/ajpgi.00550.2010, ISSN: 1522-1547.

McElroy SJ, Weitkamp JH. Innate Immunity in the Small Intestine of the Preterm Infant. Neoreviews. 2011 Sep 9/1/2011; 12(9): e517-e526. PMID: 22639551, PMCID: PMC3359837, DOI: 10.1542/neo.12-9-e517.

Lytkin NI, McVoy L, Weitkamp JH, Aliferis CF, Statnikov A. Expanding the understanding of biases in development of clinical-grade molecular signatures: a case study in acute respiratory viral infections. PLoS ONE [print-electronic]. 2011; 6(6): e20662. PMID: 21673802, PMCID: PMC3105991, PII: PONE-D-11-01252, DOI: 10.1371/journal.pone.0020662, ISSN: 1932-6203.

Halpern MD, Weitkamp JH, Mount Patrick SK, Dobrenen HJ, Khailova L, Correa H, Dvorak B. Apical sodium-dependent bile acid transporter upregulation is associated with necrotizing enterocolitis. Am. J. Physiol. Gastrointest. Liver Physiol [print-electronic]. 2010 Sep; 299(3): G623-31. PMID: 20616306, PMCID: PMC2950692, PII: ajpgi.00242.2010, DOI: 10.1152/ajpgi.00242.2010, ISSN: 1522-1547.

Hill ML, Baldwin L, Slaughter JC, Walsh WF, Weitkamp JH. A silver-alginate-coated dressing to reduce peripherally inserted central catheter (PICC) infections in NICU patients: a pilot randomized controlled trial. J Perinatol [print-electronic]. 2010 Jul; 30(7): 469-73. PMID: 20010613, PII: jp2009190, DOI: 10.1038/jp.2009.190, ISSN: 1476-5543.

Statnikov A, Lytkin NI, McVoy L, Weitkamp JH, Aliferis CF. Using gene expression profiles from peripheral blood to identify asymptomatic responses to acute respiratory viral infections. BMC Res Notes. 2010; 3: 264. PMID: 20961438, PMCID: PMC2975649, PII: 1756-0500-3-264, DOI: 10.1186/1756-0500-3-264, ISSN: 1756-0500.

Williams JV, Weitkamp JH, Blum DL, LaFleur BJ, Crowe JE. The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol. Immunol [print-electronic]. 2009 Dec; 47(2-3): 407-14. PMID: 19804909, PMCID: PMC2788105, PII: S0161-5890(09)00701-9, DOI: 10.1016/j.molimm.2009.08.024, ISSN: 1872-9142.

Weitkamp JH, Rudzinski E, Koyama T, Correa H, Matta P, Alberty B, Polk DB. Ontogeny of FOXP3(+) regulatory T cells in the postnatal human small intestinal and large intestinal lamina propria. Pediatr. Dev. Pathol. 2009 Nov; 12(6): 443-9. PMID: 19203136, PMCID: PMC2844857, PII: 08-09-0533, DOI: 10.2350/08-09-0533.1, ISSN: 1093-5266.

Weitkamp JH, Ozdas A, LaFleur B, Potts AL. Fluconazole prophylaxis for prevention of invasive fungal infections in targeted highest risk preterm infants limits drug exposure. J Perinatol [print-electronic]. 2008 Jun; 28(6): 405-11. PMID: 18185518, PII: 7211914, DOI: 10.1038/, ISSN: 0743-8346.

Sparks JR, Recchia FM, Weitkamp JH. Endogenous group B streptococcal endophthalmitis in a preterm infant. J Perinatol. 2007 Jun; 27(6): 392-4. PMID: 17522689, PII: 7211685, DOI: 10.1038/, ISSN: 0743-8346.

Choudhury SA, Berthaud V, Weitkamp JH. Meningitis caused by Salmonella panama in infants. J Natl Med Assoc. 2006 Feb; 98(2): 219-22. PMID: 16708507, PMCID: PMC2595037, ISSN: 1943-4693.

Weitkamp JH, Lafleur BJ, Crowe JE. Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells. Hum. Immunol [print-electronic]. 2006 Jan; 67(1-2): 33-42. PMID: 16698423, PII: S0198-8859(06)00011-5, DOI: 10.1016/j.humimm.2006.02.024, ISSN: 0198-8859.

Weitkamp JH, Lafleur BJ, Greenberg HB, Crowe JE. Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes. Hum. Immunol. 2005 Jun; 66(6): 666-76. PMID: 15993712, PII: S0198-8859(05)00060-1, DOI: 10.1016/j.humimm.2005.02.008, ISSN: 0198-8859.

Weitkamp JH, Kallewaard NL, Bowen AL, Lafleur BJ, Greenberg HB, Crowe JE. VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7. J. Immunol. 2005 Mar 3/15/2005; 174(6): 3454-60. PMID: 15749880, PII: 174/6/3454, ISSN: 0022-1767.

Weitkamp JH, Spring MD, Brogan T, Moses H, Bloch KC, Wright PF. Influenza A virus-associated acute necrotizing encephalopathy in the United States. Pediatr. Infect. Dis. J. 2004 Mar; 23(3): 259-63. PMID: 15014305, PII: 00006454-200403000-00019, ISSN: 0891-3668.

Weitkamp JH, Kallewaard N, Kusuhara K, Bures E, Williams JV, LaFleur B, Greenberg HB, Crowe JE. Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J. Immunol. 2003 Nov 11/1/2003; 171(9): 4680-8. PMID: 14568943, ISSN: 0022-1767.

Weitkamp JH, Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE. Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J. Immunol. Methods. 2003 Apr 4/1/2003; 275(1-2): 223-37. PMID: 12667686, PII: S0022175903000139, ISSN: 0022-1759.

Weitkamp JH, Reinsberg J, Bartmann P. Interleukin-8 (IL-8) preferable to IL-6 as a marker for clinical infection [letter]. Clin. Diagn. Lab. Immunol. 2002 Nov; 9(6): 1401. PMID: 12414787, PMCID: PMC130121, ISSN: 1071-412X.

Weitkamp JH, Crowe JE. Blood donor leukocyte reduction filters as a source of human B lymphocytes. BioTechniques. 2001 Sep; 31(3): 464-6. PMID: 11570486, ISSN: 0736-6205.

Crowe JE, Suara RO, Brock S, Kallewaard N, House F, Weitkamp JH. Genetic and structural determinants of virus neutralizing antibodies. Immunol. Res. 2001; 23(2-3): 135-45. PMID: 11444379, PII: IR:23:2-3:135, DOI: 10.1385/IR:23:2-3:135, ISSN: 0257-277X.

Weitkamp JH, Tang YW, Haas DW, Midha NK, Crowe JE. Recurrent Achromobacter xylosoxidans bacteremia associated with persistent lymph node infection in a patient with hyper-immunoglobulin M syndrome. Clin. Infect. Dis [print-electronic]. 2000 Nov; 31(5): 1183-7. PMID: 11073750, PII: CID994327, DOI: 10.1086/317461, ISSN: 1058-4838.

Weitkamp JH, Stüber F, Bartmann P. Pilot study assessing TNF gene polymorphism as a prognostic marker for disease progression in neonates with sepsis. Infection. 2000 Mar; 28(2): 92-6. PMID: 10782394, ISSN: 0300-8126.

Weitkamp JH, Poets CF, Sievers R, Musswessels E, Groneck P, Thomas P, Bartmann P. Candida infection in very low birth-weight infants: outcome and nephrotoxicity of treatment with liposomal amphotericin B (AmBisome). Infection. 1998 Jan; 26(1): 11-5. PMID: 9505173, ISSN: 0300-8126.

Weitkamp JH, Pérez-Pérez GI, Bode G, Malfertheiner P, Blaser MJ. Identification and characterization of Helicobacter pylori phospholipase C activity. Zentralbl. Bakteriol. 1993 Sep; 280(1-2): 11-27. PMID: 8280931, ISSN: 0934-8840.