Faculty Appointments
Associate Professor of Pediatrics
Associate Professor of Pathology, Microbiology and Immunology
Education
M.D., MEDICINE, University of Pennsylvania, Philadelphia, PennsylvaniaPh.D., IMMUNOLOGY, University of Pennsylvania, Philadelphia, PennsylvaniaA.B., Harvard University, Cambridge, Massachusetts
Office Address
11136 DOT
2200 Children's Way
Nashville, TN 37232
2200 Children's Way
Nashville, TN 37232
Research Description
Our research seeks to understand the cellular and molecular mechanisms that govern immune tolerance in order to prevent and reverse Type 1 Diabetes, enhance the success of organ transplantation, and limit immune-mediated tissue injury. My graduate research as an MSTP student at Penn contributed to the understanding of the role played by B lymphocytes in the development of autoimmune disease. This research formed part of the foundation for current efforts to use B cell directed therapies to prevent diabetes, studies in which Vanderbilt is participating through the Type 1 Diabetes TrialNet and for which I participate as a co-investigator. We also previously demonstrated that B lymphocytes are absolutely required for some forms of transplantation tolerance induction in murine models. These studies suggest the presence of regulatory B cells which have yet to be defined. A main present focus of the lab is to understand how B lymphocytes and other regulatory immune cells control immune tolerance to transplants and how these cells are involved in broken tolerance in autoimmune disease such as Type 1 diabetes.
My research has been funded by the National Institutes of Health, the American Diabetes Association, and the Juvenile Diabetes Research Foundation. I serve as a reviewer for the Journal of Immunology, Diabetes, and the American Journal of Transplantation, among others. Our research has been presented at the Scientific Sessions of the American Diabetes Association, the annual meeting of the Pediatric Academic Societies, the Immunology of Diabetes Society, and the American Transplant Congress. We have published in the Journal of Immunology, Diabetes, Transplantation International, the Journal of Autoimmunity, Nature Medicine, PNAS, and other top journals. Our research program has also been recognized by the Society for Pediatric Research with the 2007 House Officer Research Award and by Vanderbilt University with the David Karzon, Joe M. Strayhorn, Elliot V. Newman, and Vanderbilt Scholar in Diabetes Awards.
My research has been funded by the National Institutes of Health, the American Diabetes Association, and the Juvenile Diabetes Research Foundation. I serve as a reviewer for the Journal of Immunology, Diabetes, and the American Journal of Transplantation, among others. Our research has been presented at the Scientific Sessions of the American Diabetes Association, the annual meeting of the Pediatric Academic Societies, the Immunology of Diabetes Society, and the American Transplant Congress. We have published in the Journal of Immunology, Diabetes, Transplantation International, the Journal of Autoimmunity, Nature Medicine, PNAS, and other top journals. Our research program has also been recognized by the Society for Pediatric Research with the 2007 House Officer Research Award and by Vanderbilt University with the David Karzon, Joe M. Strayhorn, Elliot V. Newman, and Vanderbilt Scholar in Diabetes Awards.
Research Keywords
Immune tolerance, Type 1 diabetes, T lymphocytes, B lymphocytes, Tregs, Bergs, immune metabolism, autoimmunity, transplantation, immune therapy
Clinical Research Keywords
Type 1 diabetes
Immune Tolerance
Transplantation Immunology
Immune Therapy
Publications
Wright JJ, Dulaney A, Williams JM, Hilmes MA, Du L, Kang H, Powers AC, Moore DJ, Virostko J. Longitudinal MRI Shows Progressive Decline in Pancreas Size and Altered Pancreas Shape in Type 1 Diabetes. J Clin Endocrinol Metab [print-electronic]. 2023 Mar 3/20/2023; PMID: 36938587, PII: 7080799, DOI: 10.1210/clinem/dgad150, ISSN: 1945-7197.
Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, . Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care [print-electronic]. 2023 Mar 3/15/2023; PMID: 36920087, PII: 148547, DOI: 10.2337/dc22-2200, ISSN: 1935-5548.
Wright JJ, Williams JM, Letourneau-Freiberg LR, Kandasamy B, Reyes D, Kanegusuku AG, Philipson L, Greeley SAW, Hilmes MA, Powers AC, Virostko J, Moore DJ. Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas. Diabetes Care [print-electronic]. 2023 Feb 2/1/2023; PMID: 36724370, PII: 148385, DOI: 10.2337/dc22-2082, ISSN: 1935-5548.
Duffus SH, Slaughter JC, Cooley W, Sharif N, Rainer K, Coate KC, Jaser SS, Moore DJ, Niswender KD, Gregory JM. A pragmatic low carbohydrate diet intervention changes neither carbohydrate consumption nor glycemia in adolescents and young adults with type 1 diabetes in a randomized trial. Pediatr Diabetes [print-electronic]. 2022 Nov; 23(7): 1088-100. PMID: 36004391, DOI: 10.1111/pedi.13407, ISSN: 1399-5448.
Keiner ES, Slaughter JC, Datye KA, Cherrington AD, Moore DJ, Gregory JM. COVID-19 Exacerbates Insulin Resistance During Diabetic Ketoacidosis in Pediatric Patients With Type 1 Diabetes. Diabetes Care [print-electronic]. 2022 Aug 8/9/2022; PMID: 35944264, PII: 147406, DOI: 10.2337/dc22-0396, ISSN: 1935-5548.
Wilson CS, Hoopes EM, Falk AC, Moore DJ. A human IgM enriched immunoglobulin preparation, Pentaglobin, reverses autoimmune diabetes without immune suppression in NOD mice. Sci Rep. 2022 Jul 7/11/2022; 12(1): 11731. PMID: 35821261, PMCID: PMC9274958, PII: 10.1038/s41598-022-15676-8, DOI: 10.1038/s41598-022-15676-8, ISSN: 2045-2322.
McNew KL, Abraham A, Sack DE, Smart CD, Pettway YD, Falk AC, Lister RL, Faucon AB, Bejan CA, Capra JA, Aronoff DM, Boyd KL, Moore DJ. Vascular alterations impede fragile tolerance to pregnancy in type 1 diabetes. F S Sci [print-electronic]. 2022 May; 3(2): 148-58. PMID: 35560012, PII: S2666-335X(22)00014-3, DOI: 10.1016/j.xfss.2022.02.001, ISSN: 2666-335X.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. Erratum. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care 2021;44:526-532. Diabetes Care [print-electronic]. 2022 Mar 3/2/2022; PMID: 35235947, PII: 144623, DOI: 10.2337/dc22-er05c, ISSN: 1935-5548.
Roger R, Hilmes MA, Williams JM, Moore DJ, Powers AC, Craddock RC, Virostko J. Deep learning-based pancreas volume assessment in individuals with type 1 diabetes. BMC Med Imaging. 2022 Jan 1/5/2022; 22(1): 5. PMID: 34986790, PMCID: PMC8734282, PII: 10.1186/s12880-021-00729-7, DOI: 10.1186/s12880-021-00729-7, ISSN: 1471-2342.
Gregory JM, Moore DJ. Letter to the Editor from Justin M. Gregory: Age and Hospitalization Risk in People With Type 1 Diabetes and COVID-19: Data From the T1D Exchange Surveillance Study. J Clin Endocrinol Metab [print-electronic]. 2021 Dec 12/6/2021; PMID: 34871421, PII: 6454284, DOI: 10.1210/clinem/dgab871, ISSN: 1945-7197.
Nguyen LM, Omage JI, Noble K, McNew KL, Moore DJ, Aronoff DM, Doster RS. Group B streptococcal infection of the genitourinary tract in pregnant and non-pregnant patients with diabetes mellitus: An immunocompromised host or something more?. Am J Reprod Immunol [print-electronic]. 2021 Dec; 86(6): e13501. PMID: 34570418, PMCID: PMC8668237, DOI: 10.1111/aji.13501, ISSN: 1600-0897.
Wilson CS, Stocks BT, Hoopes EM, Rhoads JP, McNew KL, Major AS, Moore DJ. Metabolic pre-conditioning in CD4 T cells restores inducible immune tolerance in lupus prone mice. JCI Insight [print-electronic]. 2021 Aug 8/17/2021; PMID: 34403367, PII: e143245, DOI: 10.1172/jci.insight.143245, ISSN: 2379-3708.
Burns AM, Moore DJ, Forster CS, Powell W, Thammasitboon S, Hostetter MK, Weiss P, Boyer D, Ward MA, Blankenburg R, Heyman MB, Rassbach CE, McPhillips H, French A, Nguyen S, Byrne BJ, Parsons DW, Gonzalez F, Nowalk AJ, Ho J, Kumar S, Orange JS, Ackerman KG. Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey [editorial]. J Pediatr [print-electronic]. 2021 Jul 7/16/2021; PMID: 34280401, PII: S0022-3476(21)00679-X, DOI: 10.1016/j.jpeds.2021.07.014, ISSN: 1097-6833.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. Response to Comment on Gregory et al. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care 2021;44:526-532 [letter]. Diabetes Care. 2021 May; 44(5): e103-e104. PMID: 33972321, PMCID: PMC8132332, PII: dci21-0005, DOI: 10.2337/dci21-0005, ISSN: 1935-5548.
Tilden DR, Datye KA, Moore DJ, French B, Jaser SS. The Rapid Transition to Telemedicine and Its Effect on Access to Care for Patients With Type 1 Diabetes During the COVID-19 Pandemic. Diabetes Care [print-electronic]. 2021 Apr 4/13/2021; PMID: 33849938, PMCID: PMC8247503, PII: dc20-2712, DOI: 10.2337/dc20-2712, ISSN: 1935-5548.
Gregory JM, Moore DJ. The Dual Burden of Type 1 Diabetes and COVID-19 [editorial]. Ann Intern Med [print-electronic]. 2021 Jan 1/26/2021; PMID: 33497267, DOI: 10.7326/M21-0367, ISSN: 1539-3704.
Forster CS, Nguyen ST, Powell WT, Moore DJ, Ho J, Heyman MB, Wenger TL, Gonzalez F, Hostetter M, Nowalk A, Rassbach CE, Boyer D, Weiss P, Blankenburg RL, Orange JS, Ackerman KG, Burns AM, . Perspectives from the Society for Pediatric Research: advice on sustaining science and mentoring during COVID-19. Pediatr Res [print-electronic]. 2021 Jan 1/19/2021; PMID: 33469179, PMCID: PMC7814517, PII: 10.1038/s41390-020-01321-5, DOI: 10.1038/s41390-020-01321-5, ISSN: 1530-0447.
Virostko J, Craddock RC, Williams JM, Triolo TM, Hilmes MA, Kang H, Du L, Wright JJ, Kinney M, Maki JH, Medved M, Waibel M, Kay TWH, Thomas HE, Greeley SAW, Steck AK, Moore DJ, Powers AC. Development of a standardized MRI protocol for pancreas assessment in humans. PLoS One. 2021; 16(8): e0256029. PMID: 34428220, PMCID: PMC8384163, PII: PONE-D-21-07115, DOI: 10.1371/journal.pone.0256029, ISSN: 1932-6203.
Joosse BA, Jackson JH, Cisneros A, Santhin AB, Smith SA, Moore DJ, Crofford LJ, Wilfong EM, Bonami RH. High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors. Front Immunol. 2021; 12: 685718. PMID: 34234784, PMCID: PMC8256427, DOI: 10.3389/fimmu.2021.685718, ISSN: 1664-3224.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care [print-electronic]. 2020 Dec 12/2/2020; PMID: 33268335, PII: dc20-2260, DOI: 10.2337/dc20-2260, ISSN: 1935-5548.
Gregory JM, Cherrington AD, Moore DJ. The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes. Diabetes. 2020 May; 69(5): 837-47. PMID: 32312900, PII: 69/5/837, DOI: 10.2337/dbi19-0026, ISSN: 1939-327X.
Williams JM, Hilmes MA, Archer B, Dulaney A, Du L, Kang H, Russell WE, Powers AC, Moore DJ, Virostko J. Repeatability and Reproducibility of Pancreas Volume Measurements Using MRI. Sci Rep. 2020 Mar 3/16/2020; 10(1): 4767. PMID: 32179809, PII: 10.1038/s41598-020-61759-9, DOI: 10.1038/s41598-020-61759-9, ISSN: 2045-2322.
Burns AM, Ackerman K, Thammasitboon S, Rassbach C, Ward MA, Blankenburg R, Forster CS, McPhillips H, Wenger T, Powell W, Heyman MB, Hogarty M, Boyer D, Hostetter M, Weiss P, Nguyen S, Parsons DW, Moore DJ, Byrne B, French A, Orange JS. Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency. Pediatr. Res [print-electronic]. 2020 Mar 3/16/2020; PMID: 32179872, PII: 10.1038/s41390-020-0837-2, DOI: 10.1038/s41390-020-0837-2, ISSN: 1530-0447.
Dei-Tutu SA, Manful A, Heimburger DC, Malechi H, Moore DJ, Oppong SA, Russell WE, Aliyu MH. Correlating maternal iodine status with neonatal thyroid function in two hospital populations in Ghana: a multicenter cross-sectional pilot study. BMC Pediatr. 2020 Jan 1/21/2020; 20(1): 26. PMID: 31964362, PII: 10.1186/s12887-020-1932-6, DOI: 10.1186/s12887-020-1932-6, ISSN: 1471-2431.
Stocks BT, Wilson CS, Marshall AF, Hoopes EM, Moore DJ. Regulation of Diabetogenic Immunity by IL15-Activated Regulatory CD8 T Cells in Type 1 Diabetes. J. Immunol [print-electronic]. 2019 May 5/24/2019; PMID: 31127035, PII: jimmunol.1800976, DOI: 10.4049/jimmunol.1800976, ISSN: 1550-6606.
Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison to GCK-MODY (MODY2). Diabetes [print-electronic]. 2019 May 5/15/2019; PMID: 31092478, PII: db19-0324, DOI: 10.2337/db19-0324, ISSN: 1939-327X.
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ. B lymphocytes protect islet ß cells in diabetes prone NOD mice treated with imatinib. JCI Insight. 2019 Apr 4/9/2019; 5: PMID: 30964447, PII: 125317, DOI: 10.1172/jci.insight.125317, ISSN: 2379-3708.
Virostko J, Williams J, Hilmes M, Bowman C, Wright JJ, Du L, Kang H, Russell WE, Powers AC, Moore DJ. Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset. Diabetes Care [print-electronic]. 2019 Feb; 42(2): 248-57. PMID: 30552135, PMCID: PMC6341292, PII: dc18-1507, DOI: 10.2337/dc18-1507, ISSN: 1935-5548.
Benjamin JT, Moore DJ, Bennett C, van der Meer R, Royce A, Loveland R, Wynn JL. Cutting Edge: IL-1a and Not IL-1ß Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality. J. Immunol [print-electronic]. 2018 Oct 10/10/2018; PMID: 30305325, PII: jimmunol.1801089, DOI: 10.4049/jimmunol.1801089, ISSN: 1550-6606.
Wilson CS, Chhabra P, Marshall AF, Morr CV, Stocks BT, Bonami RH, Poffenberger G, Brayman KL, Moore DJ. Healthy Donor Polyclonal IgM's Diminish B Lymphocyte Autoreactivity, Enhance Treg Generation, and Reverse T1D in NOD Mice. Diabetes [print-electronic]. 2018 Aug 8/21/2018; PMID: 30131391, PII: db18-0456, DOI: 10.2337/db18-0456, ISSN: 1939-327X.
Chhabra P, Spano AJ, Bowers D, Ren T, Moore DJ, Timko MP, Wu M, Brayman KL. Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis. Ann. Surg [print-electronic]. 2018 Jul 7/9/2018; PMID: 29994931, DOI: 10.1097/SLA.0000000000002930, ISSN: 1528-1140.
Good M, McElroy SJ, Berger JN, Moore DJ, Wynn JL. Limited achievement of NIH research independence by pediatric K award recipients. Pediatr. Res [print-electronic]. 2018 Jun 6/14/2018; PMID: 29904137, PII: 10.1038/s41390-018-0056-2, DOI: 10.1038/s41390-018-0056-2, ISSN: 1530-0447.
Shen X, Liu L, Peek RM, Acra SA, Moore DJ, Wilson KT, He F, Polk DB, Yan F. Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes. Mucosal Immunol [print-electronic]. 2018 Jun 6/6/2018; PMID: 29875401, PII: 10.1038/s41385-018-0034-3, DOI: 10.1038/s41385-018-0034-3, ISSN: 1935-3456.
Martinez KA, Romano-Keeler J, Zackular JP, Moore DJ, Brucker RM, Hooper C, Meng S, Brown N, Mallal S, Reese J, Aronoff DM, Shin H, Dominguez-Bello MG, Weitkamp JH. Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice. PLoS ONE. 2018; 13(5): e0197439. PMID: 29771989, PII: PONE-D-17-43953, DOI: 10.1371/journal.pone.0197439, ISSN: 1932-6203.
Ding Y, Li H, He X, Liao W, Yi Z, Yi J, Chen Z, Moore DJ, Yi Y, Xiang W. Identification of a gene-expression predictor for diagnosis and personalized stratification of lupus patients. PLoS ONE. 2018; 13(7): e0198325. PMID: 29975701, PII: PONE-D-17-43250, DOI: 10.1371/journal.pone.0198325, ISSN: 1932-6203.
Romano-Keeler J, Shilts MH, Tovchigrechko A, Wang C, Brucker RM, Moore DJ, Fonnesbeck C, Meng S, Correa H, Lovvorn HN, Tang YW, Hooper L, Bordenstein SR, Das SR, Weitkamp JH. Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure. PLoS ONE. 2018; 13(10): e0206366. PMID: 30365522, PII: PONE-D-18-22175, DOI: 10.1371/journal.pone.0206366, ISSN: 1932-6203.
Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp JH. In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes. J. Immunol [print-electronic]. 2017 Sep 9/25/2017; PMID: 28947540, PII: jimmunol.1601880, DOI: 10.4049/jimmunol.1601880, ISSN: 1550-6606.
Stocks BT, Wilson CS, Marshall AF, Brewer LA, Moore DJ. Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance. Sci Rep. 2017 Sep 9/11/2017; 7(1): 11181. PMID: 28894277, PII: 10.1038/s41598-017-11780-2, DOI: 10.1038/s41598-017-11780-2, ISSN: 2045-2322.
Datye KA, Boyle CT, Simmons J, Moore DJ, Jaser SS, Sheanon N, Kittelsrud JM, Woerner SE, Miller KM, . Timing of Meal Insulin and Its Relation to Adherence to Therapy in Type 1 Diabetes. J Diabetes Sci Technol [print-electronic]. 2017 Sep 9/1/2017; 1932296817728525. PMID: 28895431, DOI: 10.1177/1932296817728525, ISSN: 1932-2968.
Moyo TK, Wilson CS, Moore DJ, Eischen CM. Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition. Oncogene [print-electronic]. 2017 Apr 4/3/2017; PMID: 28368423, PII: onc201795, DOI: 10.1038/onc.2017.95, ISSN: 1476-5594.
Moore DJ. ERAD-icating mutant insulin promotes functional insulin secretion. Sci Transl Med. 2017 Jan 1/18/2017; 9(373): PMID: 28100837, PII: 9/373/eaal4995, DOI: 10.1126/scitranslmed.aal4995, ISSN: 1946-6242.
Moore DJ. Grave effects of a specific immune therapy. Sci Transl Med. 2016 Nov 11/30/2016; 8(367): 367ec192. PMID: 27903860, PII: 8/367/367ec192, DOI: 10.1126/scitranslmed.aal2801, ISSN: 1946-6242.
Moore DJ. New onset diabetes mellitus after heart transplantation in children is a common but potentially modifiable burden [editorial]. Pediatr Transplant [print-electronic]. 2016 Nov; 20(7): 886-7. PMID: 27726266, DOI: 10.1111/petr.12785, ISSN: 1399-3046.
Scalea JR, Hickman JB, Moore DJ, Brayman KL. An overview of the necessary thymic contributions to tolerance in transplantation. Clin. Immunol [print-electronic]. 2016 Oct 10/27/2016; PMID: 27989896, PII: S1521-6616(16)30382-5, DOI: 10.1016/j.clim.2016.10.010, ISSN: 1521-7035.
Stocks BT, Thomas AB, Elizer SK, Zhu Y, Marshall AF, Wilson CS, Moore DJ. Hematopoietic Stem Cell Mobilization is Necessary but not Sufficient for Tolerance in Islet Transplantation. Diabetes [print-electronic]. 2016 Oct 10/26/2016; PMID: 27797908, PII: db16-0444, DOI: 10.2337/db16-0444, ISSN: 1939-327X.
Moore DJ. New onset diabetes mellitus after heart transplantation in children is a common but potentially modifiable burden. Pediatr Transplant [print-electronic]. 2016 Oct 10/10/2016; PMID: 27726266, DOI: 10.1111/petr.12785, ISSN: 1399-3046.
Wang Y, Liu L, Moore DJ, Shen X, Peek RM, Acra SA, Li H, Ren X, Polk DB, Yan F. An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells. Mucosal Immunol [print-electronic]. 2016 Jun 6/29/2016; PMID: 27353252, PII: mi201657, DOI: 10.1038/mi.2016.57, ISSN: 1935-3456.
Itani HA, McMaster WG, Saleh MA, Nazarewicz RR, Mikolajczyk TP, Kaszuba A, Konior A, Prejbisz A, Januszewicz A, Norlander AE, Chen W, Bonami RH, Marshall AF, Poffenberger G, Weyand CM, Madhur MS, Moore DJ, Harrison DG, Guzik TJ. Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension [print-electronic]. 2016 May 5/23/2016; PMID: 27217403, PII: HYPERTENSIONAHA.116.07237, DOI: 10.1161/HYPERTENSIONAHA.116.07237, ISSN: 1524-4563.
Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ. Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2016 Apr 4/25/2016; PMID: 27114524, PII: 1515793113, DOI: 10.1073/pnas.1515793113, ISSN: 1091-6490.
Yan F, Liu L, Cao H, Moore DJ, Washington MK, Wang B, Peek RM, Acra SA, Polk DB. Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood. Mucosal Immunol [print-electronic]. 2016 Apr 4/20/2016; PMID: 27095077, PII: mi201643, DOI: 10.1038/mi.2016.43, ISSN: 1935-3456.
Virostko J, Hilmes M, Eitel K, Moore DJ, Powers AC. Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes. PLoS ONE. 2016; 11(7): e0158825. PMID: 27391588, PII: PONE-D-15-41788, DOI: 10.1371/journal.pone.0158825, ISSN: 1932-6203.
Stocks BT, Wilhelm AJ, Wilson CS, Marshall AF, Putnam NE, Major AS, Moore DJ. Lupus-Prone Mice Resist Immune Regulation and Transplant Tolerance Induction. Am. J. Transplant [print-electronic]. 2015 Sep 9/15/2015; PMID: 26372909, DOI: 10.1111/ajt.13449, ISSN: 1600-6143.
Datye KA, Moore DJ, Russell WE, Jaser SS. A review of adolescent adherence in type 1 diabetes and the untapped potential of diabetes providers to improve outcomes. Curr. Diab. Rep. 2015 Aug; 15(8): 621. PMID: 26084580, DOI: 10.1007/s11892-015-0621-6, ISSN: 1539-0829.
Wynn JL, Scumpia PO, Stocks BT, Romano-Keeler J, Alrifai MW, Liu JH, Kim AS, Alford CE, Matta P, Weitkamp JH, Moore DJ. Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality. J. Immunol [print-electronic]. 2015 Aug 8/1/2015; 195(3): 1064-70. PMID: 26101326, PMCID: PMC4506905, PII: jimmunol.1500771, DOI: 10.4049/jimmunol.1500771, ISSN: 1550-6606.
Sosenko JM, Skyler JS, DiMeglio LA, Beam CA, Krischer JP, Greenbaum CJ, Boulware D, Rafkin LE, Matheson D, Herold KC, Mahon J, Palmer JP, , . A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history. Diabetes Care [print-electronic]. 2015 Feb; 38(2): 271-6. PMID: 25519451, PMCID: PMC4302258, PII: dc14-1813, DOI: 10.2337/dc14-1813, ISSN: 1935-5548.
Wilson CS, Elizer SK, Marshall AF, Stocks BT, Moore DJ. Regulation of B lymphocyte responses to Toll-like receptor ligand binding during diabetes prevention in non-obese diabetic (NOD) mice. J Diabetes [print-electronic]. 2015 Jan 1/7/2015; PMID: 25564999, PMCID: PMC4598313, DOI: 10.1111/1753-0407.12263, ISSN: 1753-0407.
Zhao G, Moore DJ, Kim JI, Lee KM, O'Connor M, Yang M, Marshall AF, Lei J, Schuetz C, Markmann JF, Deng S. An immunosufficient murine model for the study of human islets. Xenotransplantation [print-electronic]. 2014 Nov; 21(6): 567-73. PMID: 25041432, PMCID: PMC4262653, DOI: 10.1111/xen.12126, ISSN: 1399-3089.
Mouledoux JH, Albers EL, Lu Z, Saville BR, Moore DJ, Dodd DA. Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients. Pediatr Transplant [print-electronic]. 2014 Mar; 18(2): 197-203. PMID: 24372990, PMCID: PMC3988248, DOI: 10.1111/petr.12205, ISSN: 1399-3046.
Romano-Keeler J, Moore DJ, Wang C, Brucker RM, Fonnesbeck C, Slaughter JC, Li H, Curran DP, Meng S, Correa H, Lovvorn HN, Tang YW, Bordenstein S, George AL, Weitkamp JH. Early life establishment of site-specific microbial communities in the gut. Gut Microbes [print-electronic]. 2014 Mar; 5(2): 192-201. PMID: 24637795, PMCID: PMC4063844, PII: 28442, DOI: 10.4161/gmic.28442, ISSN: 1949-0984.
Weitkamp JH, Rosen MJ, Zhao Z, Koyama T, Geem D, Denning TL, Rock MT, Moore DJ, Halpern MD, Matta P, Denning PW. Small intestinal intraepithelial TCR¿d+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis. PLoS ONE. 2014; 9(6): e99042. PMID: 24905458, PMCID: PMC4048281, PII: PONE-D-14-10885, DOI: 10.1371/journal.pone.0099042, ISSN: 1932-6203.
Elizer SK, Marshall AF, Moore DJ. Dysregulation of T lymphocyte proliferative responses in autoimmunity. PLoS ONE. 2014; 9(8): e106347. PMID: 25171173, PMCID: PMC4149551, PII: PONE-D-13-30311, DOI: 10.1371/journal.pone.0106347, ISSN: 1932-6203.
DiGiandomenico A, Veach RA, Zienkiewicz J, Moore DJ, Wylezinski LS, Hutchens MA, Hawiger J. The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation. PLoS ONE. 2014; 9(10): e110183. PMID: 25329889, PMCID: PMC4203769, PII: PONE-D-14-26863, DOI: 10.1371/journal.pone.0110183, ISSN: 1932-6203.
Sosenko JM, Skyler JS, Beam CA, Krischer JP, Greenbaum CJ, Mahon J, Rafkin LE, Matheson D, Herold KC, Palmer JP, . Acceleration of the loss of the first-phase insulin response during the progression to type 1 diabetes in diabetes prevention trial-type 1 participants. Diabetes [print-electronic]. 2013 Dec; 62(12): 4179-83. PMID: 23863814, PMCID: PMC3837047, PII: db13-0656, DOI: 10.2337/db13-0656, ISSN: 1939-327X.
Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Yu L, Mahon J, Beam CA, Boulware DC, Rafkin L, Schatz D, Eisenbarth G, , . The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients. Diabetes Care [print-electronic]. 2013 Sep; 36(9): 2615-20. PMID: 23818528, PMCID: PMC3747899, PII: dc13-0425, DOI: 10.2337/dc13-0425, ISSN: 1935-5548.
Gregory JM, Moore DJ, Simmons JH. Type 1 diabetes mellitus. Pediatr Rev. 2013 May; 34(5): 203-15. PMID: 23637249, PII: 34/5/203, DOI: 10.1542/pir.34-5-203, ISSN: 1526-3347.
, , Buckingham BA, Beck RW, Ruedy KJ, Cheng P, Kollman C, Weinzimer SA, DiMeglio LA, Bremer AA, Slover R, Cantwell M. The effects of inpatient hybrid closed-loop therapy initiated within 1 week of type 1 diabetes diagnosis. Diabetes Technol. Ther [print-electronic]. 2013 May; 15(5): 401-8. PMID: 23570538, PMCID: PMC3643224, DOI: 10.1089/dia.2013.0002, ISSN: 1557-8593.
Yeh H, Moore DJ, Markmann JF, Kim JI. Mechanisms of regulatory T cell counter-regulation by innate immunity. Transplant Rev (Orlando) [print-electronic]. 2013 Apr; 27(2): 61-4. PMID: 23474287, PMCID: PMC3637936, PII: S0955-470X(13)00021-9, DOI: 10.1016/j.trre.2013.02.001, ISSN: 1557-9816.
Liu Y, Major AS, Zienkiewicz J, Gabriel CL, Veach RA, Moore DJ, Collins RD, Hawiger J. Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver. J Am Heart Assoc. 2013 Apr; 2(2): e000093. PMID: 23563994, PMCID: PMC3647260, PII: 2/2/e000093, DOI: 10.1161/JAHA.113.000093, ISSN: 2047-9980.
Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB. Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios. Gut [print-electronic]. 2013 Jan; 62(1): 73-82. PMID: 22267598, PMCID: PMC3606820, PII: gutjnl-2011-301551, DOI: 10.1136/gutjnl-2011-301551, ISSN: 1468-3288.
Virostko J, Radhika A, Poffenberger G, Dula AN, Moore DJ, Powers AC. Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model. PLoS ONE [print-electronic]. 2013; 8(3): e57784. PMID: 23483929, PMCID: PMC3590285, PII: PONE-D-12-38112, DOI: 10.1371/journal.pone.0057784, ISSN: 1932-6203.
Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL, . Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care [print-electronic]. 2012 Jun; 35(6): 1213-8. PMID: 22446173, PMCID: PMC3357246, PII: dc11-2081, DOI: 10.2337/dc11-2081, ISSN: 1935-5548.
Shoemaker AH, Zienkiewicz J, Moore DJ. Clinical assessment of HNF1A and GCK variants and identification of a novel mutation causing MODY2. Diabetes Res. Clin. Pract [print-electronic]. 2012 May; 96(2): e36-9. PMID: 22341299, PMCID: PMC3560353, PII: S0168-8227(12)00058-7, DOI: 10.1016/j.diabres.2012.01.032, ISSN: 1872-8227.
Romano-Keeler J, Weitkamp JH, Moore DJ. Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes. Curr Opin Endocrinol Diabetes Obes. 2012 Apr; 19(2): 73-80. PMID: 22357099, PMCID: PMC3560352, DOI: 10.1097/MED.0b013e3283514d43, ISSN: 1752-2978.
Lin Q, Liu Y, Moore DJ, Elizer SK, Veach RA, Hawiger J, Ruley HE. Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. J. Immunol [print-electronic]. 2012 Mar 3/15/2012; 188(6): 2493-7. PMID: 22323537, PMCID: PMC3294148, PII: jimmunol.1101502, DOI: 10.4049/jimmunol.1101502, ISSN: 1550-6606.
Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore DJ, Yoder SM, Rock MT, Jagasia M. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood [print-electronic]. 2012 Mar 3/8/2012; 119(10): 2417-21. PMID: 22262764, PMCID: PMC3311262, PII: blood-2011-10-384750, DOI: 10.1182/blood-2011-10-384750, ISSN: 1528-0020.
Buscariollo DL, Davidson MA, Black M, Russell WE, Rothman RL, Moore DJ. Factors that influence parental attitudes toward enrollment in type 1 diabetes trials. PLoS ONE [print-electronic]. 2012; 7(8): e44341. PMID: 22937171, PMCID: PMC3429434, PII: PONE-D-11-21531, DOI: 10.1371/journal.pone.0044341, ISSN: 1932-6203.
Mathew RP, Moore DJ. Autoimmune alternating hypo- and hyperthyroidism in children. Clin Pediatr (Phila) [print-electronic]. 2011 Nov; 50(11): 1040-4. PMID: 21700620, PMCID: PMC3556509, PII: 0009922811412583, DOI: 10.1177/0009922811412583, ISSN: 1938-2707.
Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, Skyler JS, . Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet [print-electronic]. 2011 Jul 7/30/2011; 378(9789): 412-9. PMID: 21719096, PMCID: PMC3462593, PII: S0140-6736(11)60886-6, DOI: 10.1016/S0140-6736(11)60886-6, ISSN: 1474-547X.
Zhao G, Moore DJ, Kim JI, Lee KM, O'Connor MR, Duff PE, Yang M, Lei J, Markmann JF, Deng S. Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation. Sci Transl Med. 2011 Jun 6/15/2011; 3(87): 87ra52. PMID: 21677198, PMCID: PMC3767303, PII: 3/87/87ra52, DOI: 10.1126/scitranslmed.3002270, ISSN: 1946-6242.
Gregory JM, Moore DJ. Can technological solutions for diabetes replace islet cell function?. Organogenesis [print-electronic]. 2011 Jan; 7(1): 32-41. PMID: 21289480, PMCID: PMC3082032, PII: 14028, ISSN: 1555-8592.
Kim JI, Sonawane SB, Lee MK, Lee SH, Duff PE, Moore DJ, O'Connor MR, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival. Eur. J. Immunol. 2010 May; 40(5): 1369-74. PMID: 20148423, PMCID: PMC2935584, DOI: 10.1002/eji.200940046, ISSN: 1521-4141.
Zhao G, Moore DJ, Lee KM, Kim JI, Duff PE, O'Connor MR, Hirohashi T, Lei J, Yang M, Markmann JF, Deng S. An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance. Am. J. Transplant [print-electronic]. 2010 Apr; 10(4): 796-801. PMID: 20199511, PMCID: PMC2934759, PII: AJT3027, DOI: 10.1111/j.1600-6143.2010.03027.x, ISSN: 1600-6143.
Moore DJ. Accounting for chance in the calculus of autoimmune disease. Med. Hypotheses [print-electronic]. 2010 Feb; 74(2): 289-93. PMID: 19800177, PMCID: PMC2815044, PII: S0306-9877(09)00614-8, DOI: 10.1016/j.mehy.2009.09.009, ISSN: 1532-2777.
Moore DJ, Zienkiewicz J, Kendall PL, Liu D, Liu X, Veach RA, Collins RD, Hawiger J. In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. PLoS ONE. 2010; 5(10): e13235. PMID: 20949090, PMCID: PMC2950856, DOI: 10.1371/journal.pone.0013235, ISSN: 1932-6203.
Kim JI, Lee MK, Moore DJ, Sonawane SB, Duff PE, O'Connor MR, Yeh H, Lian MM, Deng S, Caton AJ, Markmann JF. Regulatory T-cell counter-regulation by innate immunity is a barrier to transplantation tolerance. Am. J. Transplant [print-electronic]. 2009 Dec; 9(12): 2736-44. PMID: 19845585, PMCID: PMC2796697, PII: AJT2847, DOI: 10.1111/j.1600-6143.2009.02847.x, ISSN: 1600-6143.
Sonawane SB, Kim JI, Lee MK, Lee SH, Duff PE, Moore DJ, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. GITR Blockade Facilitates Treg Mediated Allograft Survival. Transplantation. 2009 Nov 11/27/2009; 88(10): 1169-77. PMID: 19935370, PMCID: PMC2803064, PII: 00007890-200911270-00005, DOI: 10.1097/TP.0b013e3181ba6f85, ISSN: 1534-6080.
Kendall PL, Moore DJ, Hulbert C, Hoek KL, Khan WN, Thomas JW. Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene. J. Immunol [print-electronic]. 2009 Nov 11/15/2009; 183(10): 6403-12. PMID: 19841184, PMCID: PMC2970569, PII: jimmunol.0900367, DOI: 10.4049/jimmunol.0900367, ISSN: 1550-6606.
Moore DJ, Gregory JM, Kumah-Crystal YA, Simmons JH. Mitigating micro-and macro-vascular complications of diabetes beginning in adolescence. Vasc Health Risk Manag [print-electronic]. 2009; 5: 1015-31. PMID: 19997571, PMCID: PMC2788594, ISSN: 1178-2048.
Huang X, Moore DJ, Ketchum RJ, Nunemaker CS, Kovatchev B, McCall AL, Brayman KL. Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation. Endocr. Rev [print-electronic]. 2008 Aug; 29(5): 603-30. PMID: 18664617, PMCID: PMC2819735, PII: er.2008-0006, DOI: 10.1210/er.2008-0006, ISSN: 0163-769X.
Porrett PM, Lee MK, Lian MM, Wang J, Caton AJ, Deng S, Markmann JF, Moore DJ. A direct comparison of rejection by CD8 and CD4 T cells in a transgenic model of allotransplantation. Arch. Immunol. Ther. Exp. (Warsz.) [print-electronic]. 2008 May; 56(3): 193-200. PMID: 18512028, PMCID: PMC2766493, DOI: 10.1007/s00005-008-0019-0, ISSN: 0004-069X.
Huang X, Moore DJ, Mohiuddin M, Lian MM, Kim JI, Sonawane S, Wang J, Gu Y, Yeh H, Markmann JF, Deng S. Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance. Transplantation. 2008 Mar 3/15/2008; 85(5): 675-80. PMID: 18337659, PMCID: PMC2934773, PII: 00007890-200803150-00005, DOI: 10.1097/TP.0b013e3181663422, ISSN: 0041-1337.
Deng S, Moore DJ, Huang X, Lian MM, Mohiuddin M, Velededeoglu E, Lee MK, Sonawane S, Kim J, Wang J, Chen H, Corfe SA, Paige C, Shlomchik M, Caton A, Markmann JF. Cutting edge: transplant tolerance induced by anti-CD45RB requires B lymphocytes. J. Immunol. 2007 May 5/15/2007; 178(10): 6028-32. PMID: 17475825, PII: 178/10/6028, ISSN: 0022-1767.
Moore DJ, Kim JI, Sonawane S, Yeh H, Deng S, Lee K, Markmann JF. Progress toward antibody-induced transplantation tolerance. Crit. Rev. Immunol. 2007; 27(2): 167-218. PMID: 17725502, PII: 04b273632c9e9613,2f614a3f72acaf13, ISSN: 1040-8401.
Moore DJ, Markmann JF, Deng S. Avenues for immunomodulation and graft protection by gene therapy in transplantation. Transpl. Int. 2006 Jun; 19(6): 435-45. PMID: 16771864, PII: TRI314, DOI: 10.1111/j.1432-2277.2006.00314.x, ISSN: 0934-0874.
Lee MK, Moore DJ, Chiaccio M, Lian MM, Deng S, Mohiuddin M, Huang X, Koeberlein B, Zakheim A, Porrett PM, Barker CF, Caton AJ, Markmann JF. T-reg mediated suppression of the allograft response in the draining lymph node. Transplantation. 2006 Apr 4/15/2006; 81(7): 1063-6. PMID: 16612285, PII: 00007890-200604150-00022, DOI: 10.1097/01.tp.0000168365.80771.5a, ISSN: 0041-1337.
Deng S, Moore DJ, Huang X, Mohiuddin M, Lee MK, Velidedeoglu E, Lian MM, Chiaccio M, Sonawane S, Orlin A, Wang J, Chen H, Caton A, Zhong R, Markmann JF. Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cells. J. Immunol. 2006 Mar 3/1/2006; 176(5): 2799-807. PMID: 16493036, PII: 176/5/2799, ISSN: 0022-1767.
Wilde GE, Moore DJ, Bellah RD. Posttransplantation lymphoproliferative disorder in pediatric recipients of solid organ transplants: timing and location of disease. AJR Am J Roentgenol. 2005 Nov; 185(5): 1335-41. PMID: 16247159, PII: 185/5/1335, DOI: 10.2214/AJR.04.1546, ISSN: 0361-803X.
Moore DJ, Noorchashm H, Lin TH, Greeley SA, Naji A. NOD B-cells are insufficient to incite T-cell-mediated anti-islet autoimmunity. Diabetes. 2005 Jul; 54(7): 2019-25. PMID: 15983202, PII: 54/7/2019, ISSN: 0012-1797.
Lee MK, Moore DJ, Jarrett BP, Lian MM, Deng S, Huang X, Markmann JW, Chiaccio M, Barker CF, Caton AJ, Markmann JF. Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation. J. Immunol. 2004 Jun 6/1/2004; 172(11): 6539-44. PMID: 15153467, ISSN: 0022-1767.
Moore DJ, Huang X, Lee MK, Lian MM, Chiaccio M, Chen H, Koeberlein B, Zhong R, Markmann JF, Deng S. Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved. Transpl. Int [print-electronic]. 2004 Jun; 17(5): 261-9. PMID: 15138669, DOI: 10.1007/s00147-004-0698-3, ISSN: 0934-0874.
Song HK, Noorchashm H, Lin TH, Moore DJ, Greeley SA, Caton AJ, Naji A. Specialized CC-chemokine secretion by Th1 cells in destructive autoimmune myocarditis. J. Autoimmun. 2003 Dec; 21(4): 295-303. PMID: 14624753, PII: S0896841103001100, ISSN: 0896-8411.
Lee MK, Moore DJ, Markmann JF. Regulatory CD4+CD25+T cells in prevention of allograft rejection. Front. Biosci. 2003 Sep 9/1/2003; 8: s968-81. PMID: 12957865, ISSN: 1093-9946.
Lee MK, Huang X, Jarrett BP, Moore DJ, Desai NM, Moh Lian M, Markmann JW, Deng S, Frank A, Singer A, Velidedeoglu E, Caton AJ, Markmann AJ. Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice. Transplantation. 2003 Apr 4/27/2003; 75(8): 1415-22. PMID: 12717241, DOI: 10.1097/01.TP.0000064296.65628.6C, ISSN: 0041-1337.
Trani J, Moore DJ, Jarrett BP, Markmann JW, Lee MK, Singer A, Lian MM, Tran B, Caton AJ, Markmann JF. CD25+ immunoregulatory CD4 T cells mediate acquired central transplantation tolerance. J. Immunol. 2003 Jan 1/1/2003; 170(1): 279-86. PMID: 12496410, ISSN: 0022-1767.
Velidedeoglu E, Jarret B, Lee K, Moore D, Huang X, Deng S, Lian MM, Caton A, Markmann JF. Transgenic T cells persist in an adoptive transfer model of mouse liver transplantation tolerance. Transplant. Proc. 2002 Dec; 34(8): 3342-4. PMID: 12493468, PII: S0041134502036965, ISSN: 0041-1345.
Greeley SA, Katsumata M, Yu L, Eisenbarth GS, Moore DJ, Goodarzi H, Barker CF, Naji A, Noorchashm H. Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat. Med. 2002 Apr; 8(4): 399-402. PMID: 11927947, PII: nm0402-399, DOI: 10.1038/nm0402-399, ISSN: 1078-8956.
Greeley SA, Moore DJ, Noorchashm H, Noto LE, Rostami SY, Schlachterman A, Song HK, Koeberlein B, Barker CF, Naji A. Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice. J. Immunol. 2001 Oct 10/15/2001; 167(8): 4351-7. PMID: 11591759, ISSN: 0022-1767.
Kline JB, Moore DJ, Clevenger CV. Activation and association of the Tec tyrosine kinase with the human prolactin receptor: mapping of a Tec/Vav1-receptor binding site. Mol. Endocrinol. 2001 May; 15(5): 832-41. PMID: 11328862, DOI: 10.1210/mend.15.5.0631, ISSN: 0888-8809.
Noorchashm H, Moore DJ, Noto LE, Noorchashm N, Reed AJ, Reed AL, Song HK, Mozaffari R, Jevnikar AM, Barker CF, Naji A. Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice. J. Immunol. 2000 Oct 10/15/2000; 165(8): 4685-96. PMID: 11035112, ISSN: 0022-1767.
Shimada H, Germana S, Sonntag KC, Banerjee P, Moore D, Sachs DH, LeGuern C. MHC class II alpha/beta heterodimeric cell surface molecules expressed from a single proviral genome. Hum. Gene Ther. 1999 Sep 9/20/1999; 10(14): 2397-405. PMID: 10515459, DOI: 10.1089/10430349950017040, ISSN: 1043-0342.
Noorchashm H, Moore DJ, Lieu YK, Noorchashm N, Schlachterman A, Song HK, Barker CF, Naji A. Contribution of the innate immune system to autoimmune diabetes: a role for the CR1/CR2 complement receptors. Cell. Immunol. 1999 Jul 7/10/1999; 195(1): 75-9. PMID: 10433799, PII: S0008874999915228, DOI: 10.1006/cimm.1999.1522, ISSN: 0008-8749.
Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, . Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care [print-electronic]. 2023 Mar 3/15/2023; PMID: 36920087, PII: 148547, DOI: 10.2337/dc22-2200, ISSN: 1935-5548.
Wright JJ, Williams JM, Letourneau-Freiberg LR, Kandasamy B, Reyes D, Kanegusuku AG, Philipson L, Greeley SAW, Hilmes MA, Powers AC, Virostko J, Moore DJ. Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas. Diabetes Care [print-electronic]. 2023 Feb 2/1/2023; PMID: 36724370, PII: 148385, DOI: 10.2337/dc22-2082, ISSN: 1935-5548.
Duffus SH, Slaughter JC, Cooley W, Sharif N, Rainer K, Coate KC, Jaser SS, Moore DJ, Niswender KD, Gregory JM. A pragmatic low carbohydrate diet intervention changes neither carbohydrate consumption nor glycemia in adolescents and young adults with type 1 diabetes in a randomized trial. Pediatr Diabetes [print-electronic]. 2022 Nov; 23(7): 1088-100. PMID: 36004391, DOI: 10.1111/pedi.13407, ISSN: 1399-5448.
Keiner ES, Slaughter JC, Datye KA, Cherrington AD, Moore DJ, Gregory JM. COVID-19 Exacerbates Insulin Resistance During Diabetic Ketoacidosis in Pediatric Patients With Type 1 Diabetes. Diabetes Care [print-electronic]. 2022 Aug 8/9/2022; PMID: 35944264, PII: 147406, DOI: 10.2337/dc22-0396, ISSN: 1935-5548.
Wilson CS, Hoopes EM, Falk AC, Moore DJ. A human IgM enriched immunoglobulin preparation, Pentaglobin, reverses autoimmune diabetes without immune suppression in NOD mice. Sci Rep. 2022 Jul 7/11/2022; 12(1): 11731. PMID: 35821261, PMCID: PMC9274958, PII: 10.1038/s41598-022-15676-8, DOI: 10.1038/s41598-022-15676-8, ISSN: 2045-2322.
McNew KL, Abraham A, Sack DE, Smart CD, Pettway YD, Falk AC, Lister RL, Faucon AB, Bejan CA, Capra JA, Aronoff DM, Boyd KL, Moore DJ. Vascular alterations impede fragile tolerance to pregnancy in type 1 diabetes. F S Sci [print-electronic]. 2022 May; 3(2): 148-58. PMID: 35560012, PII: S2666-335X(22)00014-3, DOI: 10.1016/j.xfss.2022.02.001, ISSN: 2666-335X.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. Erratum. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care 2021;44:526-532. Diabetes Care [print-electronic]. 2022 Mar 3/2/2022; PMID: 35235947, PII: 144623, DOI: 10.2337/dc22-er05c, ISSN: 1935-5548.
Roger R, Hilmes MA, Williams JM, Moore DJ, Powers AC, Craddock RC, Virostko J. Deep learning-based pancreas volume assessment in individuals with type 1 diabetes. BMC Med Imaging. 2022 Jan 1/5/2022; 22(1): 5. PMID: 34986790, PMCID: PMC8734282, PII: 10.1186/s12880-021-00729-7, DOI: 10.1186/s12880-021-00729-7, ISSN: 1471-2342.
Gregory JM, Moore DJ. Letter to the Editor from Justin M. Gregory: Age and Hospitalization Risk in People With Type 1 Diabetes and COVID-19: Data From the T1D Exchange Surveillance Study. J Clin Endocrinol Metab [print-electronic]. 2021 Dec 12/6/2021; PMID: 34871421, PII: 6454284, DOI: 10.1210/clinem/dgab871, ISSN: 1945-7197.
Nguyen LM, Omage JI, Noble K, McNew KL, Moore DJ, Aronoff DM, Doster RS. Group B streptococcal infection of the genitourinary tract in pregnant and non-pregnant patients with diabetes mellitus: An immunocompromised host or something more?. Am J Reprod Immunol [print-electronic]. 2021 Dec; 86(6): e13501. PMID: 34570418, PMCID: PMC8668237, DOI: 10.1111/aji.13501, ISSN: 1600-0897.
Wilson CS, Stocks BT, Hoopes EM, Rhoads JP, McNew KL, Major AS, Moore DJ. Metabolic pre-conditioning in CD4 T cells restores inducible immune tolerance in lupus prone mice. JCI Insight [print-electronic]. 2021 Aug 8/17/2021; PMID: 34403367, PII: e143245, DOI: 10.1172/jci.insight.143245, ISSN: 2379-3708.
Burns AM, Moore DJ, Forster CS, Powell W, Thammasitboon S, Hostetter MK, Weiss P, Boyer D, Ward MA, Blankenburg R, Heyman MB, Rassbach CE, McPhillips H, French A, Nguyen S, Byrne BJ, Parsons DW, Gonzalez F, Nowalk AJ, Ho J, Kumar S, Orange JS, Ackerman KG. Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey [editorial]. J Pediatr [print-electronic]. 2021 Jul 7/16/2021; PMID: 34280401, PII: S0022-3476(21)00679-X, DOI: 10.1016/j.jpeds.2021.07.014, ISSN: 1097-6833.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. Response to Comment on Gregory et al. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care 2021;44:526-532 [letter]. Diabetes Care. 2021 May; 44(5): e103-e104. PMID: 33972321, PMCID: PMC8132332, PII: dci21-0005, DOI: 10.2337/dci21-0005, ISSN: 1935-5548.
Tilden DR, Datye KA, Moore DJ, French B, Jaser SS. The Rapid Transition to Telemedicine and Its Effect on Access to Care for Patients With Type 1 Diabetes During the COVID-19 Pandemic. Diabetes Care [print-electronic]. 2021 Apr 4/13/2021; PMID: 33849938, PMCID: PMC8247503, PII: dc20-2712, DOI: 10.2337/dc20-2712, ISSN: 1935-5548.
Gregory JM, Moore DJ. The Dual Burden of Type 1 Diabetes and COVID-19 [editorial]. Ann Intern Med [print-electronic]. 2021 Jan 1/26/2021; PMID: 33497267, DOI: 10.7326/M21-0367, ISSN: 1539-3704.
Forster CS, Nguyen ST, Powell WT, Moore DJ, Ho J, Heyman MB, Wenger TL, Gonzalez F, Hostetter M, Nowalk A, Rassbach CE, Boyer D, Weiss P, Blankenburg RL, Orange JS, Ackerman KG, Burns AM, . Perspectives from the Society for Pediatric Research: advice on sustaining science and mentoring during COVID-19. Pediatr Res [print-electronic]. 2021 Jan 1/19/2021; PMID: 33469179, PMCID: PMC7814517, PII: 10.1038/s41390-020-01321-5, DOI: 10.1038/s41390-020-01321-5, ISSN: 1530-0447.
Virostko J, Craddock RC, Williams JM, Triolo TM, Hilmes MA, Kang H, Du L, Wright JJ, Kinney M, Maki JH, Medved M, Waibel M, Kay TWH, Thomas HE, Greeley SAW, Steck AK, Moore DJ, Powers AC. Development of a standardized MRI protocol for pancreas assessment in humans. PLoS One. 2021; 16(8): e0256029. PMID: 34428220, PMCID: PMC8384163, PII: PONE-D-21-07115, DOI: 10.1371/journal.pone.0256029, ISSN: 1932-6203.
Joosse BA, Jackson JH, Cisneros A, Santhin AB, Smith SA, Moore DJ, Crofford LJ, Wilfong EM, Bonami RH. High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors. Front Immunol. 2021; 12: 685718. PMID: 34234784, PMCID: PMC8256427, DOI: 10.3389/fimmu.2021.685718, ISSN: 1664-3224.
Gregory JM, Slaughter JC, Duffus SH, Smith TJ, LeStourgeon LM, Jaser SS, McCoy AB, Luther JM, Giovannetti ER, Boeder S, Pettus JH, Moore DJ. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes. Diabetes Care [print-electronic]. 2020 Dec 12/2/2020; PMID: 33268335, PII: dc20-2260, DOI: 10.2337/dc20-2260, ISSN: 1935-5548.
Gregory JM, Cherrington AD, Moore DJ. The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes. Diabetes. 2020 May; 69(5): 837-47. PMID: 32312900, PII: 69/5/837, DOI: 10.2337/dbi19-0026, ISSN: 1939-327X.
Williams JM, Hilmes MA, Archer B, Dulaney A, Du L, Kang H, Russell WE, Powers AC, Moore DJ, Virostko J. Repeatability and Reproducibility of Pancreas Volume Measurements Using MRI. Sci Rep. 2020 Mar 3/16/2020; 10(1): 4767. PMID: 32179809, PII: 10.1038/s41598-020-61759-9, DOI: 10.1038/s41598-020-61759-9, ISSN: 2045-2322.
Burns AM, Ackerman K, Thammasitboon S, Rassbach C, Ward MA, Blankenburg R, Forster CS, McPhillips H, Wenger T, Powell W, Heyman MB, Hogarty M, Boyer D, Hostetter M, Weiss P, Nguyen S, Parsons DW, Moore DJ, Byrne B, French A, Orange JS. Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency. Pediatr. Res [print-electronic]. 2020 Mar 3/16/2020; PMID: 32179872, PII: 10.1038/s41390-020-0837-2, DOI: 10.1038/s41390-020-0837-2, ISSN: 1530-0447.
Dei-Tutu SA, Manful A, Heimburger DC, Malechi H, Moore DJ, Oppong SA, Russell WE, Aliyu MH. Correlating maternal iodine status with neonatal thyroid function in two hospital populations in Ghana: a multicenter cross-sectional pilot study. BMC Pediatr. 2020 Jan 1/21/2020; 20(1): 26. PMID: 31964362, PII: 10.1186/s12887-020-1932-6, DOI: 10.1186/s12887-020-1932-6, ISSN: 1471-2431.
Stocks BT, Wilson CS, Marshall AF, Hoopes EM, Moore DJ. Regulation of Diabetogenic Immunity by IL15-Activated Regulatory CD8 T Cells in Type 1 Diabetes. J. Immunol [print-electronic]. 2019 May 5/24/2019; PMID: 31127035, PII: jimmunol.1800976, DOI: 10.4049/jimmunol.1800976, ISSN: 1550-6606.
Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison to GCK-MODY (MODY2). Diabetes [print-electronic]. 2019 May 5/15/2019; PMID: 31092478, PII: db19-0324, DOI: 10.2337/db19-0324, ISSN: 1939-327X.
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ. B lymphocytes protect islet ß cells in diabetes prone NOD mice treated with imatinib. JCI Insight. 2019 Apr 4/9/2019; 5: PMID: 30964447, PII: 125317, DOI: 10.1172/jci.insight.125317, ISSN: 2379-3708.
Virostko J, Williams J, Hilmes M, Bowman C, Wright JJ, Du L, Kang H, Russell WE, Powers AC, Moore DJ. Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset. Diabetes Care [print-electronic]. 2019 Feb; 42(2): 248-57. PMID: 30552135, PMCID: PMC6341292, PII: dc18-1507, DOI: 10.2337/dc18-1507, ISSN: 1935-5548.
Benjamin JT, Moore DJ, Bennett C, van der Meer R, Royce A, Loveland R, Wynn JL. Cutting Edge: IL-1a and Not IL-1ß Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality. J. Immunol [print-electronic]. 2018 Oct 10/10/2018; PMID: 30305325, PII: jimmunol.1801089, DOI: 10.4049/jimmunol.1801089, ISSN: 1550-6606.
Wilson CS, Chhabra P, Marshall AF, Morr CV, Stocks BT, Bonami RH, Poffenberger G, Brayman KL, Moore DJ. Healthy Donor Polyclonal IgM's Diminish B Lymphocyte Autoreactivity, Enhance Treg Generation, and Reverse T1D in NOD Mice. Diabetes [print-electronic]. 2018 Aug 8/21/2018; PMID: 30131391, PII: db18-0456, DOI: 10.2337/db18-0456, ISSN: 1939-327X.
Chhabra P, Spano AJ, Bowers D, Ren T, Moore DJ, Timko MP, Wu M, Brayman KL. Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis. Ann. Surg [print-electronic]. 2018 Jul 7/9/2018; PMID: 29994931, DOI: 10.1097/SLA.0000000000002930, ISSN: 1528-1140.
Good M, McElroy SJ, Berger JN, Moore DJ, Wynn JL. Limited achievement of NIH research independence by pediatric K award recipients. Pediatr. Res [print-electronic]. 2018 Jun 6/14/2018; PMID: 29904137, PII: 10.1038/s41390-018-0056-2, DOI: 10.1038/s41390-018-0056-2, ISSN: 1530-0447.
Shen X, Liu L, Peek RM, Acra SA, Moore DJ, Wilson KT, He F, Polk DB, Yan F. Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes. Mucosal Immunol [print-electronic]. 2018 Jun 6/6/2018; PMID: 29875401, PII: 10.1038/s41385-018-0034-3, DOI: 10.1038/s41385-018-0034-3, ISSN: 1935-3456.
Martinez KA, Romano-Keeler J, Zackular JP, Moore DJ, Brucker RM, Hooper C, Meng S, Brown N, Mallal S, Reese J, Aronoff DM, Shin H, Dominguez-Bello MG, Weitkamp JH. Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice. PLoS ONE. 2018; 13(5): e0197439. PMID: 29771989, PII: PONE-D-17-43953, DOI: 10.1371/journal.pone.0197439, ISSN: 1932-6203.
Ding Y, Li H, He X, Liao W, Yi Z, Yi J, Chen Z, Moore DJ, Yi Y, Xiang W. Identification of a gene-expression predictor for diagnosis and personalized stratification of lupus patients. PLoS ONE. 2018; 13(7): e0198325. PMID: 29975701, PII: PONE-D-17-43250, DOI: 10.1371/journal.pone.0198325, ISSN: 1932-6203.
Romano-Keeler J, Shilts MH, Tovchigrechko A, Wang C, Brucker RM, Moore DJ, Fonnesbeck C, Meng S, Correa H, Lovvorn HN, Tang YW, Hooper L, Bordenstein SR, Das SR, Weitkamp JH. Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure. PLoS ONE. 2018; 13(10): e0206366. PMID: 30365522, PII: PONE-D-18-22175, DOI: 10.1371/journal.pone.0206366, ISSN: 1932-6203.
Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp JH. In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes. J. Immunol [print-electronic]. 2017 Sep 9/25/2017; PMID: 28947540, PII: jimmunol.1601880, DOI: 10.4049/jimmunol.1601880, ISSN: 1550-6606.
Stocks BT, Wilson CS, Marshall AF, Brewer LA, Moore DJ. Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance. Sci Rep. 2017 Sep 9/11/2017; 7(1): 11181. PMID: 28894277, PII: 10.1038/s41598-017-11780-2, DOI: 10.1038/s41598-017-11780-2, ISSN: 2045-2322.
Datye KA, Boyle CT, Simmons J, Moore DJ, Jaser SS, Sheanon N, Kittelsrud JM, Woerner SE, Miller KM, . Timing of Meal Insulin and Its Relation to Adherence to Therapy in Type 1 Diabetes. J Diabetes Sci Technol [print-electronic]. 2017 Sep 9/1/2017; 1932296817728525. PMID: 28895431, DOI: 10.1177/1932296817728525, ISSN: 1932-2968.
Moyo TK, Wilson CS, Moore DJ, Eischen CM. Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition. Oncogene [print-electronic]. 2017 Apr 4/3/2017; PMID: 28368423, PII: onc201795, DOI: 10.1038/onc.2017.95, ISSN: 1476-5594.
Moore DJ. ERAD-icating mutant insulin promotes functional insulin secretion. Sci Transl Med. 2017 Jan 1/18/2017; 9(373): PMID: 28100837, PII: 9/373/eaal4995, DOI: 10.1126/scitranslmed.aal4995, ISSN: 1946-6242.
Moore DJ. Grave effects of a specific immune therapy. Sci Transl Med. 2016 Nov 11/30/2016; 8(367): 367ec192. PMID: 27903860, PII: 8/367/367ec192, DOI: 10.1126/scitranslmed.aal2801, ISSN: 1946-6242.
Moore DJ. New onset diabetes mellitus after heart transplantation in children is a common but potentially modifiable burden [editorial]. Pediatr Transplant [print-electronic]. 2016 Nov; 20(7): 886-7. PMID: 27726266, DOI: 10.1111/petr.12785, ISSN: 1399-3046.
Scalea JR, Hickman JB, Moore DJ, Brayman KL. An overview of the necessary thymic contributions to tolerance in transplantation. Clin. Immunol [print-electronic]. 2016 Oct 10/27/2016; PMID: 27989896, PII: S1521-6616(16)30382-5, DOI: 10.1016/j.clim.2016.10.010, ISSN: 1521-7035.
Stocks BT, Thomas AB, Elizer SK, Zhu Y, Marshall AF, Wilson CS, Moore DJ. Hematopoietic Stem Cell Mobilization is Necessary but not Sufficient for Tolerance in Islet Transplantation. Diabetes [print-electronic]. 2016 Oct 10/26/2016; PMID: 27797908, PII: db16-0444, DOI: 10.2337/db16-0444, ISSN: 1939-327X.
Moore DJ. New onset diabetes mellitus after heart transplantation in children is a common but potentially modifiable burden. Pediatr Transplant [print-electronic]. 2016 Oct 10/10/2016; PMID: 27726266, DOI: 10.1111/petr.12785, ISSN: 1399-3046.
Wang Y, Liu L, Moore DJ, Shen X, Peek RM, Acra SA, Li H, Ren X, Polk DB, Yan F. An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells. Mucosal Immunol [print-electronic]. 2016 Jun 6/29/2016; PMID: 27353252, PII: mi201657, DOI: 10.1038/mi.2016.57, ISSN: 1935-3456.
Itani HA, McMaster WG, Saleh MA, Nazarewicz RR, Mikolajczyk TP, Kaszuba A, Konior A, Prejbisz A, Januszewicz A, Norlander AE, Chen W, Bonami RH, Marshall AF, Poffenberger G, Weyand CM, Madhur MS, Moore DJ, Harrison DG, Guzik TJ. Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension [print-electronic]. 2016 May 5/23/2016; PMID: 27217403, PII: HYPERTENSIONAHA.116.07237, DOI: 10.1161/HYPERTENSIONAHA.116.07237, ISSN: 1524-4563.
Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ. Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2016 Apr 4/25/2016; PMID: 27114524, PII: 1515793113, DOI: 10.1073/pnas.1515793113, ISSN: 1091-6490.
Yan F, Liu L, Cao H, Moore DJ, Washington MK, Wang B, Peek RM, Acra SA, Polk DB. Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood. Mucosal Immunol [print-electronic]. 2016 Apr 4/20/2016; PMID: 27095077, PII: mi201643, DOI: 10.1038/mi.2016.43, ISSN: 1935-3456.
Virostko J, Hilmes M, Eitel K, Moore DJ, Powers AC. Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes. PLoS ONE. 2016; 11(7): e0158825. PMID: 27391588, PII: PONE-D-15-41788, DOI: 10.1371/journal.pone.0158825, ISSN: 1932-6203.
Stocks BT, Wilhelm AJ, Wilson CS, Marshall AF, Putnam NE, Major AS, Moore DJ. Lupus-Prone Mice Resist Immune Regulation and Transplant Tolerance Induction. Am. J. Transplant [print-electronic]. 2015 Sep 9/15/2015; PMID: 26372909, DOI: 10.1111/ajt.13449, ISSN: 1600-6143.
Datye KA, Moore DJ, Russell WE, Jaser SS. A review of adolescent adherence in type 1 diabetes and the untapped potential of diabetes providers to improve outcomes. Curr. Diab. Rep. 2015 Aug; 15(8): 621. PMID: 26084580, DOI: 10.1007/s11892-015-0621-6, ISSN: 1539-0829.
Wynn JL, Scumpia PO, Stocks BT, Romano-Keeler J, Alrifai MW, Liu JH, Kim AS, Alford CE, Matta P, Weitkamp JH, Moore DJ. Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality. J. Immunol [print-electronic]. 2015 Aug 8/1/2015; 195(3): 1064-70. PMID: 26101326, PMCID: PMC4506905, PII: jimmunol.1500771, DOI: 10.4049/jimmunol.1500771, ISSN: 1550-6606.
Sosenko JM, Skyler JS, DiMeglio LA, Beam CA, Krischer JP, Greenbaum CJ, Boulware D, Rafkin LE, Matheson D, Herold KC, Mahon J, Palmer JP, , . A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history. Diabetes Care [print-electronic]. 2015 Feb; 38(2): 271-6. PMID: 25519451, PMCID: PMC4302258, PII: dc14-1813, DOI: 10.2337/dc14-1813, ISSN: 1935-5548.
Wilson CS, Elizer SK, Marshall AF, Stocks BT, Moore DJ. Regulation of B lymphocyte responses to Toll-like receptor ligand binding during diabetes prevention in non-obese diabetic (NOD) mice. J Diabetes [print-electronic]. 2015 Jan 1/7/2015; PMID: 25564999, PMCID: PMC4598313, DOI: 10.1111/1753-0407.12263, ISSN: 1753-0407.
Zhao G, Moore DJ, Kim JI, Lee KM, O'Connor M, Yang M, Marshall AF, Lei J, Schuetz C, Markmann JF, Deng S. An immunosufficient murine model for the study of human islets. Xenotransplantation [print-electronic]. 2014 Nov; 21(6): 567-73. PMID: 25041432, PMCID: PMC4262653, DOI: 10.1111/xen.12126, ISSN: 1399-3089.
Mouledoux JH, Albers EL, Lu Z, Saville BR, Moore DJ, Dodd DA. Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients. Pediatr Transplant [print-electronic]. 2014 Mar; 18(2): 197-203. PMID: 24372990, PMCID: PMC3988248, DOI: 10.1111/petr.12205, ISSN: 1399-3046.
Romano-Keeler J, Moore DJ, Wang C, Brucker RM, Fonnesbeck C, Slaughter JC, Li H, Curran DP, Meng S, Correa H, Lovvorn HN, Tang YW, Bordenstein S, George AL, Weitkamp JH. Early life establishment of site-specific microbial communities in the gut. Gut Microbes [print-electronic]. 2014 Mar; 5(2): 192-201. PMID: 24637795, PMCID: PMC4063844, PII: 28442, DOI: 10.4161/gmic.28442, ISSN: 1949-0984.
Weitkamp JH, Rosen MJ, Zhao Z, Koyama T, Geem D, Denning TL, Rock MT, Moore DJ, Halpern MD, Matta P, Denning PW. Small intestinal intraepithelial TCR¿d+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis. PLoS ONE. 2014; 9(6): e99042. PMID: 24905458, PMCID: PMC4048281, PII: PONE-D-14-10885, DOI: 10.1371/journal.pone.0099042, ISSN: 1932-6203.
Elizer SK, Marshall AF, Moore DJ. Dysregulation of T lymphocyte proliferative responses in autoimmunity. PLoS ONE. 2014; 9(8): e106347. PMID: 25171173, PMCID: PMC4149551, PII: PONE-D-13-30311, DOI: 10.1371/journal.pone.0106347, ISSN: 1932-6203.
DiGiandomenico A, Veach RA, Zienkiewicz J, Moore DJ, Wylezinski LS, Hutchens MA, Hawiger J. The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation. PLoS ONE. 2014; 9(10): e110183. PMID: 25329889, PMCID: PMC4203769, PII: PONE-D-14-26863, DOI: 10.1371/journal.pone.0110183, ISSN: 1932-6203.
Sosenko JM, Skyler JS, Beam CA, Krischer JP, Greenbaum CJ, Mahon J, Rafkin LE, Matheson D, Herold KC, Palmer JP, . Acceleration of the loss of the first-phase insulin response during the progression to type 1 diabetes in diabetes prevention trial-type 1 participants. Diabetes [print-electronic]. 2013 Dec; 62(12): 4179-83. PMID: 23863814, PMCID: PMC3837047, PII: db13-0656, DOI: 10.2337/db13-0656, ISSN: 1939-327X.
Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Yu L, Mahon J, Beam CA, Boulware DC, Rafkin L, Schatz D, Eisenbarth G, , . The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients. Diabetes Care [print-electronic]. 2013 Sep; 36(9): 2615-20. PMID: 23818528, PMCID: PMC3747899, PII: dc13-0425, DOI: 10.2337/dc13-0425, ISSN: 1935-5548.
Gregory JM, Moore DJ, Simmons JH. Type 1 diabetes mellitus. Pediatr Rev. 2013 May; 34(5): 203-15. PMID: 23637249, PII: 34/5/203, DOI: 10.1542/pir.34-5-203, ISSN: 1526-3347.
, , Buckingham BA, Beck RW, Ruedy KJ, Cheng P, Kollman C, Weinzimer SA, DiMeglio LA, Bremer AA, Slover R, Cantwell M. The effects of inpatient hybrid closed-loop therapy initiated within 1 week of type 1 diabetes diagnosis. Diabetes Technol. Ther [print-electronic]. 2013 May; 15(5): 401-8. PMID: 23570538, PMCID: PMC3643224, DOI: 10.1089/dia.2013.0002, ISSN: 1557-8593.
Yeh H, Moore DJ, Markmann JF, Kim JI. Mechanisms of regulatory T cell counter-regulation by innate immunity. Transplant Rev (Orlando) [print-electronic]. 2013 Apr; 27(2): 61-4. PMID: 23474287, PMCID: PMC3637936, PII: S0955-470X(13)00021-9, DOI: 10.1016/j.trre.2013.02.001, ISSN: 1557-9816.
Liu Y, Major AS, Zienkiewicz J, Gabriel CL, Veach RA, Moore DJ, Collins RD, Hawiger J. Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver. J Am Heart Assoc. 2013 Apr; 2(2): e000093. PMID: 23563994, PMCID: PMC3647260, PII: 2/2/e000093, DOI: 10.1161/JAHA.113.000093, ISSN: 2047-9980.
Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB. Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios. Gut [print-electronic]. 2013 Jan; 62(1): 73-82. PMID: 22267598, PMCID: PMC3606820, PII: gutjnl-2011-301551, DOI: 10.1136/gutjnl-2011-301551, ISSN: 1468-3288.
Virostko J, Radhika A, Poffenberger G, Dula AN, Moore DJ, Powers AC. Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model. PLoS ONE [print-electronic]. 2013; 8(3): e57784. PMID: 23483929, PMCID: PMC3590285, PII: PONE-D-12-38112, DOI: 10.1371/journal.pone.0057784, ISSN: 1932-6203.
Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL, . Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care [print-electronic]. 2012 Jun; 35(6): 1213-8. PMID: 22446173, PMCID: PMC3357246, PII: dc11-2081, DOI: 10.2337/dc11-2081, ISSN: 1935-5548.
Shoemaker AH, Zienkiewicz J, Moore DJ. Clinical assessment of HNF1A and GCK variants and identification of a novel mutation causing MODY2. Diabetes Res. Clin. Pract [print-electronic]. 2012 May; 96(2): e36-9. PMID: 22341299, PMCID: PMC3560353, PII: S0168-8227(12)00058-7, DOI: 10.1016/j.diabres.2012.01.032, ISSN: 1872-8227.
Romano-Keeler J, Weitkamp JH, Moore DJ. Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes. Curr Opin Endocrinol Diabetes Obes. 2012 Apr; 19(2): 73-80. PMID: 22357099, PMCID: PMC3560352, DOI: 10.1097/MED.0b013e3283514d43, ISSN: 1752-2978.
Lin Q, Liu Y, Moore DJ, Elizer SK, Veach RA, Hawiger J, Ruley HE. Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. J. Immunol [print-electronic]. 2012 Mar 3/15/2012; 188(6): 2493-7. PMID: 22323537, PMCID: PMC3294148, PII: jimmunol.1101502, DOI: 10.4049/jimmunol.1101502, ISSN: 1550-6606.
Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore DJ, Yoder SM, Rock MT, Jagasia M. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood [print-electronic]. 2012 Mar 3/8/2012; 119(10): 2417-21. PMID: 22262764, PMCID: PMC3311262, PII: blood-2011-10-384750, DOI: 10.1182/blood-2011-10-384750, ISSN: 1528-0020.
Buscariollo DL, Davidson MA, Black M, Russell WE, Rothman RL, Moore DJ. Factors that influence parental attitudes toward enrollment in type 1 diabetes trials. PLoS ONE [print-electronic]. 2012; 7(8): e44341. PMID: 22937171, PMCID: PMC3429434, PII: PONE-D-11-21531, DOI: 10.1371/journal.pone.0044341, ISSN: 1932-6203.
Mathew RP, Moore DJ. Autoimmune alternating hypo- and hyperthyroidism in children. Clin Pediatr (Phila) [print-electronic]. 2011 Nov; 50(11): 1040-4. PMID: 21700620, PMCID: PMC3556509, PII: 0009922811412583, DOI: 10.1177/0009922811412583, ISSN: 1938-2707.
Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, Skyler JS, . Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet [print-electronic]. 2011 Jul 7/30/2011; 378(9789): 412-9. PMID: 21719096, PMCID: PMC3462593, PII: S0140-6736(11)60886-6, DOI: 10.1016/S0140-6736(11)60886-6, ISSN: 1474-547X.
Zhao G, Moore DJ, Kim JI, Lee KM, O'Connor MR, Duff PE, Yang M, Lei J, Markmann JF, Deng S. Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation. Sci Transl Med. 2011 Jun 6/15/2011; 3(87): 87ra52. PMID: 21677198, PMCID: PMC3767303, PII: 3/87/87ra52, DOI: 10.1126/scitranslmed.3002270, ISSN: 1946-6242.
Gregory JM, Moore DJ. Can technological solutions for diabetes replace islet cell function?. Organogenesis [print-electronic]. 2011 Jan; 7(1): 32-41. PMID: 21289480, PMCID: PMC3082032, PII: 14028, ISSN: 1555-8592.
Kim JI, Sonawane SB, Lee MK, Lee SH, Duff PE, Moore DJ, O'Connor MR, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival. Eur. J. Immunol. 2010 May; 40(5): 1369-74. PMID: 20148423, PMCID: PMC2935584, DOI: 10.1002/eji.200940046, ISSN: 1521-4141.
Zhao G, Moore DJ, Lee KM, Kim JI, Duff PE, O'Connor MR, Hirohashi T, Lei J, Yang M, Markmann JF, Deng S. An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance. Am. J. Transplant [print-electronic]. 2010 Apr; 10(4): 796-801. PMID: 20199511, PMCID: PMC2934759, PII: AJT3027, DOI: 10.1111/j.1600-6143.2010.03027.x, ISSN: 1600-6143.
Moore DJ. Accounting for chance in the calculus of autoimmune disease. Med. Hypotheses [print-electronic]. 2010 Feb; 74(2): 289-93. PMID: 19800177, PMCID: PMC2815044, PII: S0306-9877(09)00614-8, DOI: 10.1016/j.mehy.2009.09.009, ISSN: 1532-2777.
Moore DJ, Zienkiewicz J, Kendall PL, Liu D, Liu X, Veach RA, Collins RD, Hawiger J. In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. PLoS ONE. 2010; 5(10): e13235. PMID: 20949090, PMCID: PMC2950856, DOI: 10.1371/journal.pone.0013235, ISSN: 1932-6203.
Kim JI, Lee MK, Moore DJ, Sonawane SB, Duff PE, O'Connor MR, Yeh H, Lian MM, Deng S, Caton AJ, Markmann JF. Regulatory T-cell counter-regulation by innate immunity is a barrier to transplantation tolerance. Am. J. Transplant [print-electronic]. 2009 Dec; 9(12): 2736-44. PMID: 19845585, PMCID: PMC2796697, PII: AJT2847, DOI: 10.1111/j.1600-6143.2009.02847.x, ISSN: 1600-6143.
Sonawane SB, Kim JI, Lee MK, Lee SH, Duff PE, Moore DJ, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. GITR Blockade Facilitates Treg Mediated Allograft Survival. Transplantation. 2009 Nov 11/27/2009; 88(10): 1169-77. PMID: 19935370, PMCID: PMC2803064, PII: 00007890-200911270-00005, DOI: 10.1097/TP.0b013e3181ba6f85, ISSN: 1534-6080.
Kendall PL, Moore DJ, Hulbert C, Hoek KL, Khan WN, Thomas JW. Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene. J. Immunol [print-electronic]. 2009 Nov 11/15/2009; 183(10): 6403-12. PMID: 19841184, PMCID: PMC2970569, PII: jimmunol.0900367, DOI: 10.4049/jimmunol.0900367, ISSN: 1550-6606.
Moore DJ, Gregory JM, Kumah-Crystal YA, Simmons JH. Mitigating micro-and macro-vascular complications of diabetes beginning in adolescence. Vasc Health Risk Manag [print-electronic]. 2009; 5: 1015-31. PMID: 19997571, PMCID: PMC2788594, ISSN: 1178-2048.
Huang X, Moore DJ, Ketchum RJ, Nunemaker CS, Kovatchev B, McCall AL, Brayman KL. Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation. Endocr. Rev [print-electronic]. 2008 Aug; 29(5): 603-30. PMID: 18664617, PMCID: PMC2819735, PII: er.2008-0006, DOI: 10.1210/er.2008-0006, ISSN: 0163-769X.
Porrett PM, Lee MK, Lian MM, Wang J, Caton AJ, Deng S, Markmann JF, Moore DJ. A direct comparison of rejection by CD8 and CD4 T cells in a transgenic model of allotransplantation. Arch. Immunol. Ther. Exp. (Warsz.) [print-electronic]. 2008 May; 56(3): 193-200. PMID: 18512028, PMCID: PMC2766493, DOI: 10.1007/s00005-008-0019-0, ISSN: 0004-069X.
Huang X, Moore DJ, Mohiuddin M, Lian MM, Kim JI, Sonawane S, Wang J, Gu Y, Yeh H, Markmann JF, Deng S. Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance. Transplantation. 2008 Mar 3/15/2008; 85(5): 675-80. PMID: 18337659, PMCID: PMC2934773, PII: 00007890-200803150-00005, DOI: 10.1097/TP.0b013e3181663422, ISSN: 0041-1337.
Deng S, Moore DJ, Huang X, Lian MM, Mohiuddin M, Velededeoglu E, Lee MK, Sonawane S, Kim J, Wang J, Chen H, Corfe SA, Paige C, Shlomchik M, Caton A, Markmann JF. Cutting edge: transplant tolerance induced by anti-CD45RB requires B lymphocytes. J. Immunol. 2007 May 5/15/2007; 178(10): 6028-32. PMID: 17475825, PII: 178/10/6028, ISSN: 0022-1767.
Moore DJ, Kim JI, Sonawane S, Yeh H, Deng S, Lee K, Markmann JF. Progress toward antibody-induced transplantation tolerance. Crit. Rev. Immunol. 2007; 27(2): 167-218. PMID: 17725502, PII: 04b273632c9e9613,2f614a3f72acaf13, ISSN: 1040-8401.
Moore DJ, Markmann JF, Deng S. Avenues for immunomodulation and graft protection by gene therapy in transplantation. Transpl. Int. 2006 Jun; 19(6): 435-45. PMID: 16771864, PII: TRI314, DOI: 10.1111/j.1432-2277.2006.00314.x, ISSN: 0934-0874.
Lee MK, Moore DJ, Chiaccio M, Lian MM, Deng S, Mohiuddin M, Huang X, Koeberlein B, Zakheim A, Porrett PM, Barker CF, Caton AJ, Markmann JF. T-reg mediated suppression of the allograft response in the draining lymph node. Transplantation. 2006 Apr 4/15/2006; 81(7): 1063-6. PMID: 16612285, PII: 00007890-200604150-00022, DOI: 10.1097/01.tp.0000168365.80771.5a, ISSN: 0041-1337.
Deng S, Moore DJ, Huang X, Mohiuddin M, Lee MK, Velidedeoglu E, Lian MM, Chiaccio M, Sonawane S, Orlin A, Wang J, Chen H, Caton A, Zhong R, Markmann JF. Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cells. J. Immunol. 2006 Mar 3/1/2006; 176(5): 2799-807. PMID: 16493036, PII: 176/5/2799, ISSN: 0022-1767.
Wilde GE, Moore DJ, Bellah RD. Posttransplantation lymphoproliferative disorder in pediatric recipients of solid organ transplants: timing and location of disease. AJR Am J Roentgenol. 2005 Nov; 185(5): 1335-41. PMID: 16247159, PII: 185/5/1335, DOI: 10.2214/AJR.04.1546, ISSN: 0361-803X.
Moore DJ, Noorchashm H, Lin TH, Greeley SA, Naji A. NOD B-cells are insufficient to incite T-cell-mediated anti-islet autoimmunity. Diabetes. 2005 Jul; 54(7): 2019-25. PMID: 15983202, PII: 54/7/2019, ISSN: 0012-1797.
Lee MK, Moore DJ, Jarrett BP, Lian MM, Deng S, Huang X, Markmann JW, Chiaccio M, Barker CF, Caton AJ, Markmann JF. Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation. J. Immunol. 2004 Jun 6/1/2004; 172(11): 6539-44. PMID: 15153467, ISSN: 0022-1767.
Moore DJ, Huang X, Lee MK, Lian MM, Chiaccio M, Chen H, Koeberlein B, Zhong R, Markmann JF, Deng S. Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved. Transpl. Int [print-electronic]. 2004 Jun; 17(5): 261-9. PMID: 15138669, DOI: 10.1007/s00147-004-0698-3, ISSN: 0934-0874.
Song HK, Noorchashm H, Lin TH, Moore DJ, Greeley SA, Caton AJ, Naji A. Specialized CC-chemokine secretion by Th1 cells in destructive autoimmune myocarditis. J. Autoimmun. 2003 Dec; 21(4): 295-303. PMID: 14624753, PII: S0896841103001100, ISSN: 0896-8411.
Lee MK, Moore DJ, Markmann JF. Regulatory CD4+CD25+T cells in prevention of allograft rejection. Front. Biosci. 2003 Sep 9/1/2003; 8: s968-81. PMID: 12957865, ISSN: 1093-9946.
Lee MK, Huang X, Jarrett BP, Moore DJ, Desai NM, Moh Lian M, Markmann JW, Deng S, Frank A, Singer A, Velidedeoglu E, Caton AJ, Markmann AJ. Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice. Transplantation. 2003 Apr 4/27/2003; 75(8): 1415-22. PMID: 12717241, DOI: 10.1097/01.TP.0000064296.65628.6C, ISSN: 0041-1337.
Trani J, Moore DJ, Jarrett BP, Markmann JW, Lee MK, Singer A, Lian MM, Tran B, Caton AJ, Markmann JF. CD25+ immunoregulatory CD4 T cells mediate acquired central transplantation tolerance. J. Immunol. 2003 Jan 1/1/2003; 170(1): 279-86. PMID: 12496410, ISSN: 0022-1767.
Velidedeoglu E, Jarret B, Lee K, Moore D, Huang X, Deng S, Lian MM, Caton A, Markmann JF. Transgenic T cells persist in an adoptive transfer model of mouse liver transplantation tolerance. Transplant. Proc. 2002 Dec; 34(8): 3342-4. PMID: 12493468, PII: S0041134502036965, ISSN: 0041-1345.
Greeley SA, Katsumata M, Yu L, Eisenbarth GS, Moore DJ, Goodarzi H, Barker CF, Naji A, Noorchashm H. Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat. Med. 2002 Apr; 8(4): 399-402. PMID: 11927947, PII: nm0402-399, DOI: 10.1038/nm0402-399, ISSN: 1078-8956.
Greeley SA, Moore DJ, Noorchashm H, Noto LE, Rostami SY, Schlachterman A, Song HK, Koeberlein B, Barker CF, Naji A. Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice. J. Immunol. 2001 Oct 10/15/2001; 167(8): 4351-7. PMID: 11591759, ISSN: 0022-1767.
Kline JB, Moore DJ, Clevenger CV. Activation and association of the Tec tyrosine kinase with the human prolactin receptor: mapping of a Tec/Vav1-receptor binding site. Mol. Endocrinol. 2001 May; 15(5): 832-41. PMID: 11328862, DOI: 10.1210/mend.15.5.0631, ISSN: 0888-8809.
Noorchashm H, Moore DJ, Noto LE, Noorchashm N, Reed AJ, Reed AL, Song HK, Mozaffari R, Jevnikar AM, Barker CF, Naji A. Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice. J. Immunol. 2000 Oct 10/15/2000; 165(8): 4685-96. PMID: 11035112, ISSN: 0022-1767.
Shimada H, Germana S, Sonntag KC, Banerjee P, Moore D, Sachs DH, LeGuern C. MHC class II alpha/beta heterodimeric cell surface molecules expressed from a single proviral genome. Hum. Gene Ther. 1999 Sep 9/20/1999; 10(14): 2397-405. PMID: 10515459, DOI: 10.1089/10430349950017040, ISSN: 1043-0342.
Noorchashm H, Moore DJ, Lieu YK, Noorchashm N, Schlachterman A, Song HK, Barker CF, Naji A. Contribution of the innate immune system to autoimmune diabetes: a role for the CR1/CR2 complement receptors. Cell. Immunol. 1999 Jul 7/10/1999; 195(1): 75-9. PMID: 10433799, PII: S0008874999915228, DOI: 10.1006/cimm.1999.1522, ISSN: 0008-8749.
Available Postdoctoral Position Details
Posted: 12/30/2015
We would welcome a highly motivated, energetic investigator to join our team studying mechanisms of immune regulation in transplantation and autoimmunity. Experience in mouse models of autoimmunity, and methods in cellular and molecular immunology is highly desirable. Please send a CV and also review our recent publications relating to transplantation, autoimmunity, and diabetes and provide a specific aims page (up to 1 page) describing what you would propose to work on in the lab.
We would welcome a highly motivated, energetic investigator to join our team studying mechanisms of immune regulation in transplantation and autoimmunity. Experience in mouse models of autoimmunity, and methods in cellular and molecular immunology is highly desirable. Please send a CV and also review our recent publications relating to transplantation, autoimmunity, and diabetes and provide a specific aims page (up to 1 page) describing what you would propose to work on in the lab.