Wesley H. Self, M.D.

Professor

wesley.self@vanderbilt.edu

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Faculty Appointments
Professor of Emergency Medicine
Education
M.P.H., Public Health, Vanderbilt University, Nashville, TennesseeM.D., MEDICINE, University of Virginia, Charlottesville, VirginiaB.S., Davidson College, Davidson, North Carolina
Office Address
1313 21st Ave S
703 Oxford House
Nashville, TN 37232
Research Description
Dr. Self is a physician-scientist focusing on improving the treatment of patients with infectious diseases and critical illness in the emergency department. His research involves disease entities such as pneumonia, sepsis, influenza, and soft tissue infections. He leads emergency department-based clinical trials, epidemiologic studies, and patient safety initiatives.
Research Keywords
emergency medicine; resuscitation; infectious diseases; pragmatic clinical trials; epidemiology; patient safety
Clinical Research Keywords
Emergency Medicine, Infectious Diseases, Pneumonia, Sepsis, Epidemiology, Quality Improvement, Patient Safety
Publications
McNaughton CD, Brown NJ, Rothman RL, Liu D, Kabagambe EK, Levy PD, Self WH, Storrow AB, Collins SP, Roumie CL. Systolic Blood Pressure and Biochemical Assessment of Adherence: A Cross-Sectional Analysis in the Emergency Department. Hypertension [print-electronic]. 2017 Aug; 70(2): 307-14. PMID: 28652467, PII: HYPERTENSIONAHA.117.09659, DOI: 10.1161/HYPERTENSIONAHA.117.09659, ISSN: 1524-4563.

Thompson CM, Self WH, Barrett TW. Nonoperative Management of Appendicitis: A Paradigm Shift?: July 2017 Annals of Emergency Medicine Journal Club. Ann Emerg Med. 2017 Jul; 70(1): 101-2. PMID: 28645384, PII: S0196-0644(17)30540-1, DOI: 10.1016/j.annemergmed.2017.04.047, ISSN: 1097-6760.

Bramley AM, Reed C, Finelli L, Self WH, Ampofo K, Arnold SR, Williams DJ, Grijalva CG, Anderson EJ, Stockmann C, Trabue C, Fakhran S, Balk R, McCullers JA, Pavia AT, Edwards KM, Wunderink RG, Jain S, . Relationship between Body Mass Index and Outcomes among Hospitalized Patients with Community-acquired Pneumonia. J. Infect. Dis [print-electronic]. 2017 May 5/17/2017; PMID: 28520948, PII: 3830171, DOI: 10.1093/infdis/jix241, ISSN: 1537-6613.

Semler MW, Wanderer JP, Ehrenfeld JM, Stollings JL, Self WH, Siew ED, Wang L, Byrne DW, Shaw AD, Bernard GR, Rice TW, , . Balanced Crystalloids versus Saline in the Intensive Care Unit. The SALT Randomized Trial. Am. J. Respir. Crit. Care Med. 2017 May 5/15/2017; 195(10): 1362-72. PMID: 27749094, PMCID: PMC5443900, DOI: 10.1164/rccm.201607-1345OC, ISSN: 1535-4970.

Schuetz P, Birkhahn R, Sherwin R, Jones AE, Singer A, Kline JA, Runyon MS, Self WH, Courtney DM, Nowak RM, Gaieski DF, Ebmeyer S, Johannes S, Wiemer JC, Schwabe A, Shapiro NI. Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. Crit. Care Med. 2017 May; 45(5): 781-9. PMID: 28257335, PMCID: PMC5389588, DOI: 10.1097/CCM.0000000000002321, ISSN: 1530-0293.

Self WH, Semler MW, Wanderer JP, Ehrenfeld JM, Byrne DW, Wang L, Atchison L, Felbinger M, Jones ID, Russ S, Shaw AD, Bernard GR, Rice TW. Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial. Trials. 2017 Apr 4/13/2017; 18(1): 178. PMID: 28407811, PMCID: PMC5390477, PII: 10.1186/s13063-017-1923-6, DOI: 10.1186/s13063-017-1923-6, ISSN: 1745-6215.

Self WH, Balk RA, Grijalva CG, Williams DJ, Zhu Y, Anderson EJ, Waterer GW, Courtney DM, Bramley AM, Trabue C, Fakhran S, Blaschke AJ, Jain S, Edwards KM, Wunderink RG. Procalcitonin as a Marker of Etiology in Adults Hospitalized with Community-Acquired Pneumonia. Clin. Infect. Dis [print-electronic]. 2017 Apr 4/12/2017; PMID: 28407054, PII: 3605415, DOI: 10.1093/cid/cix317, ISSN: 1537-6591.

Semler MW, Self WH, Wang L, Byrne DW, Wanderer JP, Ehrenfeld JM, Stollings JL, Kumar AB, Hernandez A, Guillamondegui OD, May AK, Siew ED, Shaw AD, Bernard GR, Rice TW, , . Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial. Trials. 2017 Mar 3/16/2017; 18(1): 129. PMID: 28302179, PMCID: PMC5356286, PII: 10.1186/s13063-017-1871-1, DOI: 10.1186/s13063-017-1871-1, ISSN: 1745-6215.

Henning DJ, Puskarich MA, Self WH, Howell MD, Donnino MW, Yealy DM, Jones AE, Shapiro NI. An Emergency Department Validation of the SEP-3 Sepsis and Septic Shock Definitions and Comparison With 1992 Consensus Definitions. Ann Emerg Med [print-electronic]. 2017 Mar 3/2/2017; PMID: 28262318, PII: S0196-0644(17)30023-9, DOI: 10.1016/j.annemergmed.2017.01.008, ISSN: 1097-6760.

Huckins DS, Copeland K, Self W, Vance C, Hendry P, Borg K, Gogain J. Diagnostic performance of a biomarker panel as a negative predictor for acute appendicitis in adult ED patients with abdominal pain. Am J Emerg Med [print-electronic]. 2017 Mar; 35(3): 418-24. PMID: 27876541, PII: S0735-6757(16)30836-1, DOI: 10.1016/j.ajem.2016.11.027, ISSN: 1532-8171.

Stockmann C, Ampofo K, Killpack J, Williams DJ, Edwards KM, Grijalva CG, Arnold SR, McCullers JA, Anderson EJ, Wunderink RG, Self WH, Bramley A, Jain S, Pavia AT, Blaschke AJ. Procalcitonin Accurately Identifies Hospitalized Children With Low Risk of Bacterial Community-Acquired Pneumonia. J Pediatric Infect Dis Soc [print-electronic]. 2017 Feb 2/3/2017; PMID: 28158460, PII: 2966998, DOI: 10.1093/jpids/piw091, ISSN: 2048-7207.

Smith AT, Wrenn KD, Barrett TW, Jones ID, Rohde JP, Slovis CM, Russ S, Self WH. Delayed intracranial hemorrhage after head trauma in patients on direct-acting oral anticoagulants. Am J Emerg Med [print-electronic]. 2017 Feb; 35(2): 377.e1-377.e2. PMID: 27592462, PII: S0735-6757(16)30511-3, DOI: 10.1016/j.ajem.2016.08.024, ISSN: 1532-8171.

Upchurch CP, Grijalva CG, Russ S, Collins SP, Semler MW, Rice TW, Liu D, Ehrenfeld JM, High K, Barrett TW, McNaughton CD, Self WH. Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients. Ann Emerg Med. 2017 Jan; 69(1): 24-33.e2. PMID: 27993308, PMCID: PMC5180365, PII: S0196-0644(16)30467-X, DOI: 10.1016/j.annemergmed.2016.08.009, ISSN: 1097-6760.

Wolff BJ, Bramley AM, Thurman KA, Whitney CG, Whitaker B, Self WH, Arnold SR, Trabue C, Wunderink RG, McCullers J, Edwards KM, Jain S, Winchell JM. Improved Detection of Respiratory Pathogens by Use of High-Quality Sputum with TaqMan Array Card Technology. J. Clin. Microbiol [electronic-print]. 2017 Jan; 55(1): 110-21. PMID: 27795345, PMCID: PMC5228222, PII: JCM.01805-16, DOI: 10.1128/JCM.01805-16, ISSN: 1098-660X.

Zhang Y, Sakthivel SK, Bramley A, Jain S, Haynes A, Chappell JD, Hymas W, Lenny N, Patel A, Qi C, Ampofo K, Arnold SR, Self WH, Williams DJ, Hillyard D, Anderson EJ, Grijalva CG, Zhu Y, Wunderink RG, Edwards KM, Pavia AT, McCullers JA, Erdman DD. Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia. J. Clin. Microbiol [electronic-print]. 2017 Jan; 55(1): 79-89. PMID: 27795341, PMCID: PMC5228265, PII: JCM.01701-16, DOI: 10.1128/JCM.01701-16, ISSN: 1098-660X.

Wu WK, Yiadom MY, Collins SP, Self WH, Monahan K. Documentation of HEART score discordance between emergency physician and cardiologist evaluations of ED patients with chest pain. Am J Emerg Med [print-electronic]. 2017 Jan; 35(1): 132-5. PMID: 27745728, PII: S0735-6757(16)30659-3, DOI: 10.1016/j.ajem.2016.09.058, ISSN: 1532-8171.

Harris AM, Bramley AM, Jain S, Arnold SR, Ampofo K, Self WH, Williams DJ, Anderson EJ, Grijalva CG, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Winchell JM, Hicks LA. Influence of Antibiotics on the Detection of Bacteria by Culture-Based and Culture-Independent Diagnostic Tests in Patients Hospitalized With Community-Acquired Pneumonia. Open Forum Infect Dis. 2017; 4(1): ofx014. PMID: 28480285, PMCID: PMC5414111, PII: ofx014, DOI: 10.1093/ofid/ofx014, ISSN: 2328-8957.

Oboho IK, Bramley A, Finelli L, Fry A, Ampofo K, Arnold SR, Self WH, Williams DJ, Courtney DM, Zhu Y, Anderson EJ, Grijalva CG, McCullers JA, Wunderink RG, Pavia AT, Edwards KM, Jain S. Oseltamivir Use Among Children and Adults Hospitalized With Community-Acquired Pneumonia. Open Forum Infect Dis. 2017; 4(1): ofw254. PMID: 28480248, PMCID: PMC5413989, PII: ofw254, DOI: 10.1093/ofid/ofw254, ISSN: 2328-8957.

Ward MJ, Self WH, Singer A, Lazar D, Pines JM. Cost-effectiveness analysis of early point-of-care lactate testing in the emergency department. J Crit Care [print-electronic]. 2016 Dec; 36: 69-75. PMID: 27546750, PII: S0883-9441(16)30173-3, DOI: 10.1016/j.jcrc.2016.06.031, ISSN: 1557-8615.

Barrett TW, Rising KL, Bellolio MF, Hall MK, Brody A, Dodd KW, Grieser M, Levy PD, Raja AS, Self WH, Weingarten G, Hess EP, Hollander JE. The 2016 Academic Emergency Medicine Consensus Conference, "Shared Decision Making in the Emergency Department: Development of a Policy-relevant Patient-centered Research Agenda" Diagnostic Testing Breakout Session Report. Acad Emerg Med [print-electronic]. 2016 Dec; 23(12): 1354-61. PMID: 27404959, PMCID: PMC5145733, DOI: 10.1111/acem.13050, ISSN: 1553-2712.

Self WH, Wunderink RG, Williams DJ, Waterer GW, Jain S, Edwards KM, Grijalva CG. Reply to Chalmers et al [letter]. Clin. Infect. Dis [print-electronic]. 2016 Oct 10/15/2016; 63(8): 1146-7. PMID: 27402823, PMCID: PMC5036917, PII: ciw466, DOI: 10.1093/cid/ciw466, ISSN: 1537-6591.

Williams DJ, Zhu Y, Grijalva CG, Self WH, Harrell FE, Reed C, Stockmann C, Arnold SR, Ampofo KK, Anderson EJ, Bramley AM, Wunderink RG, McCullers JA, Pavia AT, Jain S, Edwards KM. Predicting Severe Pneumonia Outcomes in Children. Pediatrics. 2016 Oct; 138(4): PMID: 27688362, PMCID: PMC5051209, PII: peds.2016-1019, DOI: 10.1542/peds.2016-1019, ISSN: 1098-4275.

Heung M, Ortega LM, Chawla LS, Wunderink RG, Self WH, Koyner JL, Shi J, Kellum JA, . Common chronic conditions do not affect performance of cell cycle arrest biomarkers for risk stratification of acute kidney injury. Nephrol. Dial. Transplant [print-electronic]. 2016 Oct; 31(10): 1633-40. PMID: 27342582, PMCID: PMC5039344, PII: gfw241, DOI: 10.1093/ndt/gfw241, ISSN: 1460-2385.

Barrett TW, Wrenn KD, Slovis CM, Jones ID, Wright PW, Self WH, Russ S, Collins SP, Ward MJ, Felbinger M, Atchison L, Beckman JA. An Outpatient Management Protocol for Emergency Department Patients With a Newly Diagnosed Lower Extremity Deep Venous Thrombosis. Crit Pathw Cardiol. 2016 Sep; 15(3): 75-6. PMID: 27464999, PMCID: PMC4968588, PII: 00132577-201609000-00001, DOI: 10.1097/HPC.0000000000000089, ISSN: 1535-2811.

Ward MJ, Kripalani S, Zhu Y, Storrow AB, Wang TJ, Speroff T, Munoz D, Dittus RS, Harrell FE, Self WH. Role of Health Insurance Status in Interfacility Transfers of Patients With ST-Elevation Myocardial Infarction. Am. J. Cardiol [print-electronic]. 2016 Aug 8/1/2016; 118(3): 332-7. PMID: 27282834, PMCID: PMC4949088, PII: S0002-9149(16)30861-X, DOI: 10.1016/j.amjcard.2016.05.007, ISSN: 1879-1913.

Semler MW, Rice TW, Shaw AD, Siew ED, Self WH, Kumar AB, Byrne DW, Ehrenfeld JM, Wanderer JP. Identification of Major Adverse Kidney Events Within the Electronic Health Record. J Med Syst [print-electronic]. 2016 Jul; 40(7): 167. PMID: 27234478, PII: 10.1007/s10916-016-0528-z, DOI: 10.1007/s10916-016-0528-z, ISSN: 1573-689X.

Havers F, Bramley AM, Finelli L, Reed C, Self WH, Trabue C, Fakhran S, Balk R, Courtney DM, Girard TD, Anderson EJ, Grijalva CG, Edwards KM, Wunderink RG, Jain S. Statin Use and Hospital Length of Stay Among Adults Hospitalized With Community-acquired Pneumonia. Clin. Infect. Dis [print-electronic]. 2016 Jun 6/15/2016; 62(12): 1471-8. PMID: 27169476, PII: ciw174, DOI: 10.1093/cid/ciw174, ISSN: 1537-6591.

Self WH, Wunderink RG, Williams DJ, Zhu Y, Anderson EJ, Balk RA, Fakhran SS, Chappell JD, Casimir G, Courtney DM, Trabue C, Waterer GW, Bramley A, Magill S, Jain S, Edwards KM, Grijalva CG. Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes. Clin. Infect. Dis [print-electronic]. 2016 May 5/8/2016; PMID: 27161775, PII: ciw300, DOI: 10.1093/cid/ciw300, ISSN: 1537-6591.

Rupp JD, Ferre RM, Boyd JS, Dearing E, McNaughton CD, Liu D, Jarrell KL, McWade CM, Self WH. Extravasation Risk Using Ultrasound Guided Peripheral Intravenous Catheters for Computed Tomography Contrast Administration. Acad Emerg Med [print-electronic]. 2016 May 5/6/2016; PMID: 27151898, DOI: 10.1111/acem.13000, ISSN: 1553-2712.

Self WH, Grijalva CG, Williams DJ, Woodworth A, Balk RA, Fakhran S, Zhu Y, Courtney DM, Chappell J, Anderson EJ, Qi C, Waterer GW, Trabue C, Bramley AM, Jain S, Edwards KM, Wunderink RG. Procalcitonin as an Early Marker of the Need for Invasive Respiratory or Vasopressor Support in Adults with Community-Acquired Pneumonia. Chest [print-electronic]. 2016 Apr 4/20/2016; PMID: 27107491, PII: S0012-3692(16)48560-0, DOI: 10.1016/j.chest.2016.04.010, ISSN: 1931-3543.

Barrett TW, Self WH, Darbar D, Jenkins CA, Wasserman BS, Kassim NA, Casner M, Shoemaker MB. Association of atrial fibrillation risk alleles and response to acute rate control therapy. Am J Emerg Med [print-electronic]. 2016 Apr; 34(4): 735-40. PMID: 26920668, PMCID: PMC4801711, PII: S0735-6757(16)00044-9, DOI: 10.1016/j.ajem.2016.01.034, ISSN: 1532-8171.

Diaz MH, Cross KE, Benitez AJ, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self WH, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM. Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia. Open Forum Infect Dis. 2016 Mar; 3(2): ofw071. PMID: 27191004, PMCID: PMC4867659, PII: ofw071, DOI: 10.1093/ofid/ofw071, ISSN: 2328-8957.

Self WH, Storrow AB, Hartmann O, Barrett TW, Fermann GJ, Maisel AS, Struck J, Bergmann A, Collins SP. Plasma bioactive adrenomedullin as a prognostic biomarker in acute heart failure. Am J Emerg Med [print-electronic]. 2016 Feb; 34(2): 257-62. PMID: 26577429, PMCID: PMC4753125, PII: S0735-6757(15)00919-5, DOI: 10.1016/j.ajem.2015.10.033, ISSN: 1532-8171.

Smith KA, High K, Collins SP, Self WH. In Reply [letter]. Acad Emerg Med [print-electronic]. 2016 Feb; 23(2): 214. PMID: 26763737, DOI: 10.1111/acem.12868, ISSN: 1553-2712.

Grijalva CG, Wunderink RG, Zhu Y, Williams DJ, Balk R, Fakhran S, Courtney DM, Anderson EJ, Qi C, Trabue C, Pavia AT, Moore MR, Jain S, Edwards KM, Self WH. In-Hospital Pneumococcal Polysaccharide Vaccination Is Associated With Detection of Pneumococcal Vaccine Serotypes in Adults Hospitalized for Community-Acquired Pneumonia. Open Forum Infect Dis. 2015 Dec; 2(4): ofv135. PMID: 26512357, PMCID: PMC4621456, PII: ofv135, DOI: 10.1093/ofid/ofv135, ISSN: 2328-8957.

Hertz JT, Lescallette RD, Barrett TW, Ward MJ, Self WH. External validation of an ED protocol for reflex urine culture cancelation [letter]. Am J Emerg Med [print-electronic]. 2015 Dec; 33(12): 1838-9. PMID: 26472506, PII: S0735-6757(15)00802-5, DOI: 10.1016/j.ajem.2015.09.026, ISSN: 1532-8171.

McNaughton CD, Self WH, Zhu Y, Janke AT, Storrow AB, Levy P. Incidence of Hypertension-Related Emergency Department Visits in the United States, 2006 to 2012. Am. J. Cardiol [print-electronic]. 2015 Dec 12/1/2015; 116(11): 1717-23. PMID: 26454813, PMCID: PMC4648677, PII: S0002-9149(15)01927-X, DOI: 10.1016/j.amjcard.2015.09.007, ISSN: 1879-1913.

Migdal VL, Wu WK, Long D, McNaughton CD, Ward MJ, Self WH. Risk-benefit analysis of lumbar puncture to evaluate for nontraumatic subarachnoid hemorrhage in adult ED patients. Am J Emerg Med [print-electronic]. 2015 Nov; 33(11): 1597-601. PMID: 26189054, PMCID: PMC4628593, PII: S0735-6757(15)00534-3, DOI: 10.1016/j.ajem.2015.06.048, ISSN: 1532-8171.

Grijalva CG, Zhu Y, Williams DJ, Self WH, Ampofo K, Pavia AT, Stockmann CR, McCullers J, Arnold SR, Wunderink RG, Anderson EJ, Lindstrom S, Fry AM, Foppa IM, Finelli L, Bramley AM, Jain S, Griffin MR, Edwards KM. Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination. JAMA. 2015 Oct 10/13/2015; 314(14): 1488-97. PMID: 26436611, PMCID: PMC4688454, PII: 2450326, DOI: 10.1001/jama.2015.12160, ISSN: 1538-3598.

Lardaro T, Self WH, Barrett TW. Thirty-day mortality in ED patients with new onset atrial fibrillation and actively treated cancer. Am J Emerg Med [print-electronic]. 2015 Oct; 33(10): 1483-8. PMID: 26283615, PMCID: PMC4581961, PII: S0735-6757(15)00589-6, DOI: 10.1016/j.ajem.2015.07.033, ISSN: 1532-8171.

Ahn A, Edwards KM, Grijalva CG, Self WH, Zhu Y, Chappell JD, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Bramley AM, Jain S, Williams DJ. Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia. J. Pediatr [print-electronic]. 2015 Oct; 167(4): 869-874.e1. PMID: 26231828, PMCID: PMC4586387, PII: S0022-3476(15)00687-3, DOI: 10.1016/j.jpeds.2015.06.049, ISSN: 1097-6833.

Ward MJ, Self WH, Froehle CM. Effects of Common Data Errors in Electronic Health Records on Emergency Department Operational Performance Metrics: A Monte Carlo Simulation. Acad Emerg Med [print-electronic]. 2015 Sep; 22(9): 1085-92. PMID: 26291051, PMCID: PMC4560638, DOI: 10.1111/acem.12743, ISSN: 1553-2712.

Diaz MH, Benitez AJ, Cross KE, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self WH, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM. Molecular Detection and Characterization of Mycoplasma pneumoniae Among Patients Hospitalized With Community-Acquired Pneumonia in the United States. Open Forum Infect Dis. 2015 Sep; 2(3): ofv106. PMID: 26284257, PMCID: PMC4536330, PII: ofv106, DOI: 10.1093/ofid/ofv106, ISSN: 2328-8957.

Smith KA, High K, Collins SP, Self WH. A preprocedural checklist improves the safety of emergency department intubation of trauma patients. Acad Emerg Med [print-electronic]. 2015 Aug; 22(8): 989-92. PMID: 26194607, DOI: 10.1111/acem.12717, ISSN: 1553-2712.

Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, Bramley AM, Reed C, Grijalva CG, Anderson EJ, Courtney DM, Chappell JD, Qi C, Hart EM, Carroll F, Trabue C, Donnelly HK, Williams DJ, Zhu Y, Arnold SR, Ampofo K, Waterer GW, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, McCullers JA, Pavia AT, Edwards KM, Finelli L, . Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. N. Engl. J. Med [print-electronic]. 2015 Jul 7/30/2015; 373(5): 415-27. PMID: 26172429, DOI: 10.1056/NEJMoa1500245, ISSN: 1533-4406.

Self WH, Williams DJ, Zhu Y, Ampofo K, Pavia AT, Chappell JD, Hymas WC, Stockmann C, Bramley AM, Schneider E, Erdman D, Finelli L, Jain S, Edwards KM, Grijalva CG. Respiratory Viral Detection in Children and Adults: Comparing Asymptomatic Controls and Patients With Community-Acquired Pneumonia. J. Infect. Dis [print-electronic]. 2015 Jul 7/14/2015; PMID: 26180044, PII: jiv323, DOI: 10.1093/infdis/jiv323, ISSN: 1537-6613.

Williams DJ, Edwards KM, Self WH, Zhu Y, Ampofo K, Pavia AT, Hersh AL, Arnold SR, McCullers JA, Hicks LA, Bramley AM, Jain S, Grijalva CG. Antibiotic Choice for Children Hospitalized With Pneumonia and Adherence to National Guidelines. Pediatrics. 2015 Jul; 136(1): 44-52. PMID: 26101356, PMCID: PMC4485005, PII: peds.2014-3047, DOI: 10.1542/peds.2014-3047, ISSN: 1098-4275.

Self WH, Wunderink RG, Williams DJ, Barrett TW, Baughman AH, Grijalva CG. Comparison of clinical prediction models for resistant bacteria in community-onset pneumonia. Acad Emerg Med [print-electronic]. 2015 Jun; 22(6): 730-40. PMID: 25996620, PMCID: PMC4464985, DOI: 10.1111/acem.12672, ISSN: 1553-2712.

Wolf RB, Edwards K, Grijalva CG, Self WH, Zhu Y, Chappell J, Bramley AM, Jain S, Williams DJ. Time to clinical stability among children hospitalized with pneumonia. J Hosp Med [print-electronic]. 2015 Jun; 10(6): 380-3. PMID: 25919391, PMCID: PMC4456292, DOI: 10.1002/jhm.2370, ISSN: 1553-5606.

Barrett TW, Vermeulen MJ, Self WH, Jenkins CA, Ferreira AJ, Atzema CL. Emergency department management of atrial fibrillation in the United States versus Ontario, Canada [letter]. J. Am. Coll. Cardiol. 2015 May 5/26/2015; 65(20): 2258-60. PMID: 25998673, PMCID: PMC4519092, PII: S0735-1097(15)01583-1, DOI: 10.1016/j.jacc.2015.01.064, ISSN: 1558-3597.

Jain S, Williams DJ, Arnold SR, Ampofo K, Bramley AM, Reed C, Stockmann C, Anderson EJ, Grijalva CG, Self WH, Zhu Y, Patel A, Hymas W, Chappell JD, Kaufman RA, Kan JH, Dansie D, Lenny N, Hillyard DR, Haynes LM, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, Wunderink RG, Edwards KM, Pavia AT, McCullers JA, Finelli L, . Community-acquired pneumonia requiring hospitalization among U.S. children. N. Engl. J. Med. 2015 Feb 2/26/2015; 372(9): 835-45. PMID: 25714161, DOI: 10.1056/NEJMoa1405870, ISSN: 1533-4406.

Ward MJ, Kripalani S, Zhu Y, Storrow AB, Dittus RS, Harrell FE, Self WH. Incidence of emergency department visits for ST-elevation myocardial infarction in a recent six-year period in the United States. Am. J. Cardiol [print-electronic]. 2015 Jan 1/15/2015; 115(2): 167-70. PMID: 25465931, PMCID: PMC4276502, PII: S0002-9149(14)02008-6, DOI: 10.1016/j.amjcard.2014.10.020, ISSN: 1879-1913.

Barrett TW, Jenkins CA, Self WH. Validation of the Risk Estimator Decision Aid for Atrial Fibrillation (RED-AF) for predicting 30-day adverse events in emergency department patients with atrial fibrillation. Ann Emerg Med [print-electronic]. 2015 Jan; 65(1): 13-21.e3. PMID: 25245277, PMCID: PMC4275362, PII: S0196-0644(14)01222-0, DOI: 10.1016/j.annemergmed.2014.08.023, ISSN: 1097-6760.

Storrow AB, Jenkins CA, Self WH, Alexander PT, Barrett TW, Han JH, McNaughton CD, Heavrin BS, Gheorghiade M, Collins SP. Reply: BAG3 protein in advanced-stage heart failure [letter]. JACC Heart Fail [print-electronic]. 2014 Dec; 2(6): 675. PMID: 25262366, PII: S2213-1779(14)00322-9, DOI: 10.1016/j.jchf.2014.05.013, ISSN: 2213-1787.

Self WH, Talbot TR, Paul BR, Collins SP, Ward MJ. Cost analysis of strategies to reduce blood culture contamination in the emergency department: sterile collection kits and phlebotomy teams. Infect Control Hosp Epidemiol [print-electronic]. 2014 Aug; 35(8): 1021-8. PMID: 25026619, PMCID: PMC4100213, DOI: 10.1086/677161, ISSN: 1559-6834.

Storrow AB, Jenkins CA, Self WH, Alexander PT, Barrett TW, Han JH, McNaughton CD, Heavrin BS, Gheorghiade M, Collins SP. The burden of acute heart failure on U.S. emergency departments. JACC Heart Fail [print-electronic]. 2014 Jun; 2(3): 269-77. PMID: 24952694, PMCID: PMC4429129, PII: S2213-1779(14)00102-4, DOI: 10.1016/j.jchf.2014.01.006, ISSN: 2213-1787.

Barrett TW, Abraham RL, Self WH. Usefulness of a low CHADS2 or CHA2DS2-VASc score to predict normal diagnostic testing in emergency department patients with an acute exacerbation of previously diagnosed atrial fibrillation. Am. J. Cardiol [print-electronic]. 2014 May 5/15/2014; 113(10): 1668-73. PMID: 24666620, PMCID: PMC4160886, PII: S0002-9149(14)00715-2, DOI: 10.1016/j.amjcard.2014.02.023, ISSN: 1879-1913.

, Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC. A randomized trial of protocol-based care for early septic shock. N. Engl. J. Med [print-electronic]. 2014 May 5/1/2014; 370(18): 1683-93. PMID: 24635773, PMCID: PMC4101700, DOI: 10.1056/NEJMoa1401602, ISSN: 1533-4406.

Bihorac A, Chawla LS, Shaw AD, Al-Khafaji A, Davison DL, Demuth GE, Fitzgerald R, Gong MN, Graham DD, Gunnerson K, Heung M, Jortani S, Kleerup E, Koyner JL, Krell K, Letourneau J, Lissauer M, Miner J, Nguyen HB, Ortega LM, Self WH, Sellman R, Shi J, Straseski J, Szalados JE, Wilber ST, Walker MG, Wilson J, Wunderink R, Zimmerman J, Kellum JA. Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am. J. Respir. Crit. Care Med. 2014 Apr 4/15/2014; 189(8): 932-9. PMID: 24559465, DOI: 10.1164/rccm.201401-0077OC, ISSN: 1535-4970.

Self WH, Mickanin J, Grijalva CG, Grant FH, Henderson MC, Corley G, Blaschke Ii DG, McNaughton CD, Barrett TW, Talbot TR, Paul BR. Reducing blood culture contamination in community hospital emergency departments: a multicenter evaluation of a quality improvement intervention. Acad Emerg Med. 2014 Mar; 21(3): 274-82. PMID: 24628752, PMCID: PMC3984048, DOI: 10.1111/acem.12337, ISSN: 1553-2712.

Self WH, Griffin MR, Zhu Y, Dupont WD, Barrett TW, Grijalva CG. The high burden of pneumonia on US emergency departments during the 2009 influenza pandemic. J. Infect [print-electronic]. 2014 Feb; 68(2): 156-64. PMID: 24140066, PMCID: PMC3947237, PII: S0163-4453(13)00306-X, DOI: 10.1016/j.jinf.2013.10.005, ISSN: 1532-2742.

Serrano F, Stack LB, Thurman RJ, Phillips L, Self WH. Traumatic eye injuries: management principles for the prehospital setting. JEMS. 2013 Dec; 38(12): 56-62. PMID: 24592570, ISSN: 0197-2510.

Barrett TW, Self WH, Jenkins CA, Storrow AB, Heavrin BS, McNaughton CD, Collins SP, Goldberger JJ. Predictors of regional variations in hospitalizations following emergency department visits for atrial fibrillation. Am. J. Cardiol [print-electronic]. 2013 Nov 11/1/2013; 112(9): 1410-6. PMID: 23972347, PMCID: PMC3800489, PII: S0002-9149(13)01513-0, DOI: 10.1016/j.amjcard.2013.07.005, ISSN: 1879-1913.

McNaughton CD, Self WH, Levy PD, Barrett TW. High-Risk Patients with Hypertension: Clinical Management Options. Clin Med Rev Vasc Health. 2013 Oct 10/8/2013; 2012(4): 65-71. PMID: 23888121, PMCID: PMC3718513, DOI: 10.4137/CMRVH.S8109, ISSN: 1179-2566.

McNaughton CD, Self WH, Pines JM. Annals of Emergency Medicine Journal Club. Observational health services studies using nationwide administrative data sets: understanding strengths and limitations of the National Hospital Ambulatory Medical Care Survey: answers to the May 2013 Journal Club questions. Ann Emerg Med. 2013 Oct; 62(4): 425-30. PMID: 24054097, PMCID: PMC3870585, PII: S0196-0644(13)01177-3, DOI: 10.1016/j.annemergmed.2013.07.498, ISSN: 1097-6760.

Self WH, White SJ, McNaughton CD, Storrow AB, Slovis CM, Collins SP. Warming intravenous fluids for improved patient comfort in the emergency department: a pilot crossover randomized controlled trial. West J Emerg Med. 2013 Sep; 14(5): 542-6. PMID: 24106555, PMCID: PMC3789921, PII: wjem-14-542, DOI: 10.5811/westjem.2013.1.13303, ISSN: 1936-900X.

Self WH, Grijalva CG, Zhu Y, McNaughton CD, Barrett TW, Collins SP, Storrow AB, Griffin MR. Rates of emergency department visits due to pneumonia in the United States, July 2006-June 2009. Acad Emerg Med [print-electronic]. 2013 Sep; 20(9): 957-60. PMID: 24033659, PMCID: PMC3907184, DOI: 10.1111/acem.12203, ISSN: 1553-2712.

McNaughton CD, Self WH. Observational health services studies using nationwide administrative datasets: understanding strengths and limitations of the National Hospital Ambulatory Medical Care Survey (NHAMCS). Ann Emerg Med. 2013 May; 61(5): 593-4. PMID: 23622024, PMCID: PMC3870580, PII: S0196-0644(13)00223-0, DOI: 10.1016/j.annemergmed.2013.03.011, ISSN: 1097-6760.

Barrett TW, Self WH, Wasserman BS, McNaughton CD, Darbar D. Evaluating the HATCH score for predicting progression to sustained atrial fibrillation in ED patients with new atrial fibrillation. Am J Emerg Med [print-electronic]. 2013 May; 31(5): 792-7. PMID: 23478104, PMCID: PMC3655117, PII: S0735-6757(13)00037-5, DOI: 10.1016/j.ajem.2013.01.020, ISSN: 1532-8171.

Ford W, Self WH, Slovis C, McNaughton CD. Diabetes in the Emergency Department and Hospital: Acute Care of Diabetes Patients. Curr Emerg Hosp Med Rep. 2013 Mar 3/1/2013; 1(1): 1-9. PMID: 23997994, PMCID: PMC3756609, DOI: 10.1007/s40138-012-0007-x, ISSN: 2167-4884.

Self WH, Courtney DM, McNaughton CD, Wunderink RG, Kline JA. High discordance of chest x-ray and computed tomography for detection of pulmonary opacities in ED patients: implications for diagnosing pneumonia. Am J Emerg Med [print-electronic]. 2013 Feb; 31(2): 401-5. PMID: 23083885, PMCID: PMC3556231, PII: S0735-6757(12)00463-9, DOI: 10.1016/j.ajem.2012.08.041, ISSN: 1532-8171.

Self WH, Speroff T, Grijalva CG, McNaughton CD, Ashburn J, Liu D, Arbogast PG, Russ S, Storrow AB, Talbot TR. Reducing blood culture contamination in the emergency department: an interrupted time series quality improvement study. Acad Emerg Med. 2013 Jan; 20(1): 89-97. PMID: 23570482, PMCID: PMC3623801, DOI: 10.1111/acem.12057, ISSN: 1553-2712.

McNaughton CD, Collins SP, Kripalani S, Rothman R, Self WH, Jenkins C, Miller K, Arbogast P, Naftilan A, Dittus RS, Storrow AB. Low numeracy is associated with increased odds of 30-day emergency department or hospital recidivism for patients with acute heart failure. Circ Heart Fail [print-electronic]. 2013 Jan; 6(1): 40-6. PMID: 23230305, PMCID: PMC3663074, PII: CIRCHEARTFAILURE.112.969477, DOI: 10.1161/CIRCHEARTFAILURE.112.969477, ISSN: 1941-3297.

Hall RT, Domenico HJ, Self WH, Hain PD. Reducing the blood culture contamination rate in a pediatric emergency department and subsequent cost savings. Pediatrics [print-electronic]. 2013 Jan; 131(1): e292-7. PMID: 23209105, PII: peds.2012-1030, DOI: 10.1542/peds.2012-1030, ISSN: 1098-4275.

Self WH, Barrett TW. Is "PERC negative" adequate to rule out pulmonary embolism in the emergency department? Evaluating meta-analysis for studies of clinical prediction models: answers to the July 2012 journal club questions. Ann Emerg Med. 2012 Dec; 60(6): 803-14. PMID: 23178020, PII: S0196-0644(12)01370-4, DOI: 10.1016/j.annemergmed.2012.07.121, ISSN: 1097-6760.

Self WH, McNaughton CD, Grijalva CG, Zhu Y, Chappell JD, Williams JV, Talbot HK, Shay DK, Griffin MR. Diagnostic performance of the BinaxNow Influenza A&B rapid antigen test in ED patients. Am J Emerg Med [print-electronic]. 2012 Nov; 30(9): 1955-61. PMID: 22795995, PII: S0735-6757(12)00182-9, DOI: 10.1016/j.ajem.2012.04.018, ISSN: 1532-8171.

McNaughton C, Self WH, Jones ID, Arbogast PG, Chen N, Dittus RS, Russ S. ED crowding and the use of nontraditional beds. Am J Emerg Med [print-electronic]. 2012 Oct; 30(8): 1474-80. PMID: 22386355, PMCID: PMC3888805, PII: S0735-6757(11)00571-7, DOI: 10.1016/j.ajem.2011.12.007, ISSN: 1532-8171.

Self WH, Barrett TW. Annals of Emergency Medicine journal club. Is "PERC negative" adequate to rule out pulmonary embolism in the emergency department? Evaluating meta-analysis for studies of clinical prediction models. Ann Emerg Med. 2012 Jul; 60(1): 129-31. PMID: 22720850, PII: S0196-0644(12)00477-5, DOI: 10.1016/j.annemergmed.2012.05.006, ISSN: 1097-6760.

Self WH, Grijalva CG, Zhu Y, Talbot HK, Jules A, Widmer KE, Edwards KM, Williams JV, Shay DK, Griffin MR. Emergency department visits for influenza A(H1N1)pdm09, Davidson County, Tennessee, USA. Emerging Infect. Dis. 2012 May; 18(5): 863-5. PMID: 22516043, PMCID: PMC3358080, DOI: 10.3201/eid1805.111233, ISSN: 1080-6059.

Self WH, Speroff T, McNaughton CD, Wright PW, Miller G, Johnson JG, Daniels TL, Talbot TR. Blood culture collection through peripheral intravenous catheters increases the risk of specimen contamination among adult emergency department patients. Infect Control Hosp Epidemiol [print-electronic]. 2012 May; 33(5): 524-6. PMID: 22476282, DOI: 10.1086/665319, ISSN: 1559-6834.

McNaughton CD, Self WH, Slovis CM. Diabetes in the Emergency Department: Acute care of diabetes patients [editorial]. Clinical Diabetes. 2011; 29: 51-9.

Self WH, Barrett TW. Annals of Emergency Medicine journal club. Novel biomarkers: help or hindrance to patient care in the emergency department?: answers to the July 2010 journal club questions. Ann Emerg Med. 2010 Dec; 56(6): 692-700. PMID: 21111253, PII: S0196-0644(10)01501-5, DOI: 10.1016/j.annemergmed.2010.09.002, ISSN: 1097-6760.

Self WH, Barrett TW. Novel biomarkers: help or hindrance to patient care in the emergency department?. Ann Emerg Med. 2010 Jul; 56(1): 60-1. PMID: 20620648, PII: S0196-0644(10)00447-6, DOI: 10.1016/j.annemergmed.2010.04.026, ISSN: 1097-6760.

Self WH. Acute HIV infection: diagnosis and management in the emergency department. Emerg. Med. Clin. North Am. 2010 May; 28(2): 381-92, Table of Contents. PMID: 20413020, PII: S0733-8627(10)00003-9, DOI: 10.1016/j.emc.2010.01.002, ISSN: 1558-0539.

Lu DW, Wang EE, Self WH, Kharasch M. Patellar dislocation reduction. Acad Emerg Med. 2010 Feb; 17(2): 226. PMID: 20370752, PII: ACEM645, DOI: 10.1111/j.1553-2712.2009.00645.x, ISSN: 1553-2712.

Self WH, Wang EE, Vozenilek JA, del Castillo J, Pettineo C, Benedict L. Dynamic emergency medicine. Arthrocentesis. Acad Emerg Med. 2008 Mar; 15(3): 298. PMID: 18304064, PII: ACEM054, DOI: 10.1111/j.1553-2712.2008.00054.x, ISSN: 1553-2712.

Self WH, Pang PS. What do we really know about neurological misdiagnosis in the emergency department? [letter]. Mayo Clin. Proc. 2008 Feb; 83(2): 252; author reply 255. PMID: 18241638, PII: S0025-6196(11)60850-1, DOI: 10.4065/83.2.252, ISSN: 0025-6196.

Kyriacou DN, Yarnold PR, Soltysik RC, Self WH, Wunderink RG, Schmitt BP, Parada JP, Adams JG. Derivation of a triage algorithm for chest radiography of community-acquired pneumonia patients in the emergency department. Acad Emerg Med. 2008 Jan; 15(1): 40-4. PMID: 18211312, PII: ACEM011, DOI: 10.1111/j.1553-2712.2007.00011.x, ISSN: 1553-2712.

Self WH, Mattu A, Martin M, Holstege C, Preuss J, Brady WJ. Body surface mapping in the ED evaluation of the patient with chest pain: use of the 80-lead electrocardiogram system. Am J Emerg Med. 2006 Jan; 24(1): 87-112. PMID: 16338516, PII: S0735-6757(05)00241-X, DOI: 10.1016/j.ajem.2005.04.008, ISSN: 0735-6757.