Faculty Appointments
Research Assistant Professor of Medicine
Education
Ph.D., University of Kansas, Kansas City, KansasM.Sc., University of Bucharest, Bucharest, RomaniaB.Sc., University of Bucharest, Bucharest, Romania
Publications
Borza CM, Su Y, Chen X, Yu L, Mont S, Chetyrkin S, Voziyan P, Hudson BG, Billings PC, Jo H, Bennett JS, Degrado WF, Eckes B, Zent R, Pozzi A. Inhibition of integrin a2ß1 ameliorates glomerular injury. J. Am. Soc. Nephrol [print-electronic]. 2012 Jun; 23(6): 1027-38. PMID: 22440900, PMCID: PMC3358756, PII: ASN.2011040367, DOI: 10.1681/ASN.2011040367, ISSN: 1533-3450.
Borza CM, Pozzi A. The role of cell-extracellular matrix interactions in glomerular injury. Exp. Cell Res [print-electronic]. 2012 May 5/15/2012; 318(9): 1001-10. PMID: 22417893, PMCID: PMC3770307, PII: S0014-4827(12)00109-7, DOI: 10.1016/j.yexcr.2012.02.033, ISSN: 1090-2422.
Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J. Biol. Chem [print-electronic]. 2010 Dec 12/17/2010; 285(51): 40114-24. PMID: 20940300, PMCID: PMC3000994, PII: M110.156729, DOI: 10.1074/jbc.M110.156729, ISSN: 1083-351X.
Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Mol. Cell. Biol [print-electronic]. 2010 Jun; 30(12): 3048-58. PMID: 20368353, PMCID: PMC2876688, PII: MCB.00892-09, DOI: 10.1128/MCB.00892-09, ISSN: 1098-5549.
Pozzi A, Zent R, Chetyrkin S, Borza C, Bulus N, Chuang P, Chen D, Hudson B, Voziyan P. Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. J. Am. Soc. Nephrol [print-electronic]. 2009 Oct; 20(10): 2119-25. PMID: 19608705, PMCID: PMC2754111, PII: ASN.2008080900, DOI: 10.1681/ASN.2008080900, ISSN: 1533-3450.
Abair TD, Bulus N, Borza C, Sundaramoorthy M, Zent R, Pozzi A. Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells. Blood [print-electronic]. 2008 Oct 10/15/2008; 112(8): 3242-54. PMID: 18647959, PMCID: PMC2569176, PII: blood-2007-12-126433, DOI: 10.1182/blood-2007-12-126433, ISSN: 1528-0020.
Macias-Perez I, Borza C, Chen X, Yan X, Ibanez R, Mernaugh G, Matrisian LM, Zent R, Pozzi A. Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer. Cancer Res. 2008 Aug 8/1/2008; 68(15): 6127-35. PMID: 18676835, PMCID: PMC2801028, PII: 68/15/6127, DOI: 10.1158/0008-5472.CAN-08-1395, ISSN: 1538-7445.
Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG. Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J. Am. Soc. Nephrol [print-electronic]. 2008 Apr; 19(4): 677-84. PMID: 18235087, PMCID: PMC2390958, PII: ASN.2007070793, DOI: 10.1681/ASN.2007070793, ISSN: 1533-3450.
Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R. Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. J. Biol. Chem [print-electronic]. 2006 Jul 7/28/2006; 281(30): 20932-9. PMID: 16731529, PII: M601147200, DOI: 10.1074/jbc.M601147200, ISSN: 0021-9258.
Wu L, Borza CM, Hutt-Fletcher LM. Mutations of Epstein-Barr virus gH that are differentially able to support fusion with B cells or epithelial cells. J. Virol. 2005 Sep; 79(17): 10923-30. PMID: 16103144, PMCID: PMC1193614, PII: 79/17/10923, DOI: 10.1128/JVI.79.17.10923-10930.2005, ISSN: 0022-538X.
Nechifor M, Vaideanu C, Palamaru I, Borza C, Mindreci I. The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia. J Am Coll Nutr. 2004 Oct; 23(5): 549S-551S. PMID: 15466963, PII: 23/5/549S, ISSN: 0731-5724.
Borza CM, Morgan AJ, Turk SM, Hutt-Fletcher LM. Use of gHgL for attachment of Epstein-Barr virus to epithelial cells compromises infection. J. Virol. 2004 May; 78(10): 5007-14. PMID: 15113881, PMCID: PMC400351, ISSN: 0022-538X.
Butcovan D, Grigoriu C, Omete G, Borza C, Cîmpeanu L, Cîmpeanu C, Georgescu GI. [Primary pulmonary hypertension--morphologic study]. Rev Med Chir Soc Med Nat Iasi. 2004 Apr; 108(2): 369-73. PMID: 15688817, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Georgescu GI, Borza C, Tinica G, Sandica E, Diaconescu V. Morphological evaluation of the surgically removed aortic and mitral valves. Rev Med Chir Soc Med Nat Iasi. 2004 Jan; 108(1): 66-73. PMID: 15688759, ISSN: 0048-7848.
Butcovan D, Tinica G, Sandica E, Diaconescu V, Ivan L, Borza C, Pacuraru L, Pacuraru M, Georgescu GI. [Morphologic and clinical correlations in medullar thymoma]. Rev Med Chir Soc Med Nat Iasi. 2003 Oct; 107(4): 881-5. PMID: 14756039, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Borza C, Omete R, Balasanian M, Georgescu GI. Cardiac leiomyosarcoma. Case report. Rev Med Chir Soc Med Nat Iasi. 2003 Apr; 107(2): 453-8. PMID: 14755960, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Tinica G, Sandica E, Borza C, Neamtu M, Georgescu GI. Two cases of Marfan syndrome. Rev Med Chir Soc Med Nat Iasi. 2002 Oct; 106(4): 829-35. PMID: 14974239, ISSN: 0048-7848.
Borza CM, Hutt-Fletcher LM. Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus. Nat. Med. 2002 Jun; 8(6): 594-9. PMID: 12042810, PII: nm0602-594, DOI: 10.1038/nm0602-594, ISSN: 1078-8956.
Butcovan D, Borza C, Chisalita I, Mihaescu T, Grigoras C, Mihailovici MS. [The histopathological study of the bronchopulmonary carcinoma]. Rev Med Chir Soc Med Nat Iasi. 2001 Jul; 105(3): 509-13. PMID: 12092183, ISSN: 0048-7848.
Ruf IK, Rhyne PW, Yang H, Borza CM, Hutt-Fletcher LM, Cleveland JL, Sample JT. EBV regulates c-MYC, apoptosis, and tumorigenicity in Burkitt's lymphoma. Curr. Top. Microbiol. Immunol. 2001; 258: 153-60. PMID: 11443860, ISSN: 0070-217X.
Borza CM, Pozzi A. The role of cell-extracellular matrix interactions in glomerular injury. Exp. Cell Res [print-electronic]. 2012 May 5/15/2012; 318(9): 1001-10. PMID: 22417893, PMCID: PMC3770307, PII: S0014-4827(12)00109-7, DOI: 10.1016/j.yexcr.2012.02.033, ISSN: 1090-2422.
Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J. Biol. Chem [print-electronic]. 2010 Dec 12/17/2010; 285(51): 40114-24. PMID: 20940300, PMCID: PMC3000994, PII: M110.156729, DOI: 10.1074/jbc.M110.156729, ISSN: 1083-351X.
Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Mol. Cell. Biol [print-electronic]. 2010 Jun; 30(12): 3048-58. PMID: 20368353, PMCID: PMC2876688, PII: MCB.00892-09, DOI: 10.1128/MCB.00892-09, ISSN: 1098-5549.
Pozzi A, Zent R, Chetyrkin S, Borza C, Bulus N, Chuang P, Chen D, Hudson B, Voziyan P. Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. J. Am. Soc. Nephrol [print-electronic]. 2009 Oct; 20(10): 2119-25. PMID: 19608705, PMCID: PMC2754111, PII: ASN.2008080900, DOI: 10.1681/ASN.2008080900, ISSN: 1533-3450.
Abair TD, Bulus N, Borza C, Sundaramoorthy M, Zent R, Pozzi A. Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells. Blood [print-electronic]. 2008 Oct 10/15/2008; 112(8): 3242-54. PMID: 18647959, PMCID: PMC2569176, PII: blood-2007-12-126433, DOI: 10.1182/blood-2007-12-126433, ISSN: 1528-0020.
Macias-Perez I, Borza C, Chen X, Yan X, Ibanez R, Mernaugh G, Matrisian LM, Zent R, Pozzi A. Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer. Cancer Res. 2008 Aug 8/1/2008; 68(15): 6127-35. PMID: 18676835, PMCID: PMC2801028, PII: 68/15/6127, DOI: 10.1158/0008-5472.CAN-08-1395, ISSN: 1538-7445.
Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG. Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J. Am. Soc. Nephrol [print-electronic]. 2008 Apr; 19(4): 677-84. PMID: 18235087, PMCID: PMC2390958, PII: ASN.2007070793, DOI: 10.1681/ASN.2007070793, ISSN: 1533-3450.
Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R. Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. J. Biol. Chem [print-electronic]. 2006 Jul 7/28/2006; 281(30): 20932-9. PMID: 16731529, PII: M601147200, DOI: 10.1074/jbc.M601147200, ISSN: 0021-9258.
Wu L, Borza CM, Hutt-Fletcher LM. Mutations of Epstein-Barr virus gH that are differentially able to support fusion with B cells or epithelial cells. J. Virol. 2005 Sep; 79(17): 10923-30. PMID: 16103144, PMCID: PMC1193614, PII: 79/17/10923, DOI: 10.1128/JVI.79.17.10923-10930.2005, ISSN: 0022-538X.
Nechifor M, Vaideanu C, Palamaru I, Borza C, Mindreci I. The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia. J Am Coll Nutr. 2004 Oct; 23(5): 549S-551S. PMID: 15466963, PII: 23/5/549S, ISSN: 0731-5724.
Borza CM, Morgan AJ, Turk SM, Hutt-Fletcher LM. Use of gHgL for attachment of Epstein-Barr virus to epithelial cells compromises infection. J. Virol. 2004 May; 78(10): 5007-14. PMID: 15113881, PMCID: PMC400351, ISSN: 0022-538X.
Butcovan D, Grigoriu C, Omete G, Borza C, Cîmpeanu L, Cîmpeanu C, Georgescu GI. [Primary pulmonary hypertension--morphologic study]. Rev Med Chir Soc Med Nat Iasi. 2004 Apr; 108(2): 369-73. PMID: 15688817, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Georgescu GI, Borza C, Tinica G, Sandica E, Diaconescu V. Morphological evaluation of the surgically removed aortic and mitral valves. Rev Med Chir Soc Med Nat Iasi. 2004 Jan; 108(1): 66-73. PMID: 15688759, ISSN: 0048-7848.
Butcovan D, Tinica G, Sandica E, Diaconescu V, Ivan L, Borza C, Pacuraru L, Pacuraru M, Georgescu GI. [Morphologic and clinical correlations in medullar thymoma]. Rev Med Chir Soc Med Nat Iasi. 2003 Oct; 107(4): 881-5. PMID: 14756039, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Borza C, Omete R, Balasanian M, Georgescu GI. Cardiac leiomyosarcoma. Case report. Rev Med Chir Soc Med Nat Iasi. 2003 Apr; 107(2): 453-8. PMID: 14755960, ISSN: 0048-7848.
Butcovan D, Arsenescu C, Tinica G, Sandica E, Borza C, Neamtu M, Georgescu GI. Two cases of Marfan syndrome. Rev Med Chir Soc Med Nat Iasi. 2002 Oct; 106(4): 829-35. PMID: 14974239, ISSN: 0048-7848.
Borza CM, Hutt-Fletcher LM. Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virus. Nat. Med. 2002 Jun; 8(6): 594-9. PMID: 12042810, PII: nm0602-594, DOI: 10.1038/nm0602-594, ISSN: 1078-8956.
Butcovan D, Borza C, Chisalita I, Mihaescu T, Grigoras C, Mihailovici MS. [The histopathological study of the bronchopulmonary carcinoma]. Rev Med Chir Soc Med Nat Iasi. 2001 Jul; 105(3): 509-13. PMID: 12092183, ISSN: 0048-7848.
Ruf IK, Rhyne PW, Yang H, Borza CM, Hutt-Fletcher LM, Cleveland JL, Sample JT. EBV regulates c-MYC, apoptosis, and tumorigenicity in Burkitt's lymphoma. Curr. Top. Microbiol. Immunol. 2001; 258: 153-60. PMID: 11443860, ISSN: 0070-217X.