Faculty Appointments
Research Assistant Professor of Pharmacology
Education
Ph.D., Zoology, University of Madras, Chennai, India
Office Address
454 PRB
2200 Pierce Ave
Department of Pharmacology
Nashville, TN 37232
2200 Pierce Ave
Department of Pharmacology
Nashville, TN 37232
Publications
Ahmed MR, Zhan X, Song X, Kook S, Gurevich VV, Gurevich EV. Ubiquitin ligase parkin promotes Mdm2-arrestin interaction but inhibits arrestin ubiquitination. Biochemistry [print-electronic]. 2011 May 5/10/2011; 50(18): 3749-63. PMID: 21466165, PMCID: PMC3091828, DOI: 10.1021/bi200175q, ISSN: 1520-4995.
Bychkov E, Ahmed MR, Gurevich EV. Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia. Int. J. Neuropsychopharmacol [print-electronic]. 2011 Feb; 14(1): 1-15. PMID: 20158934, PMCID: PMC2992801, PII: S1461145710000118, DOI: 10.1017/S1461145710000118, ISSN: 1469-5111.
Ahmed MR, Berthet A, Bychkov E, Porras G, Li Q, Bioulac BH, Carl YT, Bloch B, Kook S, Aubert I, Dovero S, Doudnikoff E, Gurevich VV, Gurevich EV, Bezard E. Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease. Sci Transl Med. 2010 Apr 4/21/2010; 2(28): 28ra28. PMID: 20410529, PMCID: PMC2933751, PII: 2/28/28ra28, DOI: 10.1126/scitranslmed.3000664, ISSN: 1946-6242.
Ahmed MR, Gurevich VV, Dalby KN, Benovic JL, Gurevich EV. Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation. J. Pharmacol. Exp. Ther [print-electronic]. 2008 Apr; 325(1): 276-83. PMID: 18178904, PMCID: PMC2629350, PII: jpet.107.131987, DOI: 10.1124/jpet.107.131987, ISSN: 1521-0103.
Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment. J. Neurochem [print-electronic]. 2008 Mar; 104(6): 1622-36. PMID: 17996024, PMCID: PMC2628845, PII: JNC5104, DOI: 10.1111/j.1471-4159.2007.05104.x, ISSN: 1471-4159.
Bychkov E, Ahmed MR, Dalby KN, Gurevich EV. Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum. J. Neurochem. 2007 Aug; 102(3): 699-711. PMID: 17630981, PII: JNC4586, DOI: 10.1111/j.1471-4159.2007.04586.x, ISSN: 0022-3042.
Hanson SM, Gurevich EV, Vishnivetskiy SA, Ahmed MR, Song X, Gurevich VV. Each rhodopsin molecule binds its own arrestin. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2007 Feb 2/27/2007; 104(9): 3125-8. PMID: 17360618, PMCID: PMC1805568, PII: 0610886104, DOI: 10.1073/pnas.0610886104, ISSN: 0027-8424.
Sripriya R, Kumar MS, Ahmed MR, Sehgal PK. Collagen bilayer dressing with ciprofloxacin, an effective system for infected wound healing. J Biomater Sci Polym Ed. 2007; 18(3): 335-51. PMID: 17471769, ISSN: 0920-5063.
Dhanaraju MD, Gopinath D, Ahmed MR, Jayakumar R, Vamsadhara C. Characterization of polymeric poly(epsilon-caprolactone) injectable implant delivery system for the controlled delivery of contraceptive steroids. J Biomed Mater Res A. 2006 Jan; 76(1): 63-72. PMID: 16108044, DOI: 10.1002/jbm.a.30458, ISSN: 1549-3296.
Ahmed MR, Jayakumar R. Peripheral nerve regeneration in cell adhesive peptide incorporated collagen tubes in rat sciatic nerve -- early and better functional regain [letter]. J. Peripher. Nerv. Syst. 2005 Dec; 10(4): 390-1. PMID: 16279992, PII: JNS055, DOI: 10.1111/j.1085-9489.2005.00055.x, ISSN: 1085-9489.
Ahmed MR, Vairamuthu S, Shafiuzama M, Basha SH, Jayakumar R. Microwave irradiated collagen tubes as a better matrix for peripheral nerve regeneration. Brain Res. 2005 Jun 6/7/2005; 1046(1-2): 55-67. PMID: 15927550, PII: S0006-8993(05)00444-0, DOI: 10.1016/j.brainres.2005.03.022, ISSN: 0006-8993.
Ahmed MR, Basha SH, Gopinath D, Muthusamy R, Jayakumar R. Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. J. Peripher. Nerv. Syst. 2005 Mar; 10(1): 17-30. PMID: 15703015, PII: JNS10105, DOI: 10.1111/j.1085-9489.2005.10105.x, ISSN: 1085-9489.
Ahmed MR, Venkateshwarlu U, Jayakumar R. Multilayered peptide incorporated collagen tubules for peripheral nerve repair. Biomaterials. 2004 Jun; 25(13): 2585-94. PMID: 14751744, PII: S0142961203007683, ISSN: 0142-9612.
Ahmed MR, Gopinath D, Gomathi K, Sehgal PK, Jayakumar R. Alpha-crystallin-incorporated collagen matrices as an aid for dermal wound healing. J. Biomed. Mater. Res. Part B Appl. Biomater. 2004 May 5/15/2004; 69(2): 241-8. PMID: 15116414, DOI: 10.1002/jbm.b.30003, ISSN: 1552-4973.
Gopinath D, Ahmed MR, Gomathi K, Chitra K, Sehgal PK, Jayakumar R. Dermal wound healing processes with curcumin incorporated collagen films. Biomaterials. 2004 May; 25(10): 1911-7. PMID: 14738855, PII: S0142961203006252, ISSN: 0142-9612.
Rafiuddin Ahmed M, Jayakumar R. Peripheral nerve regeneration in RGD peptide incorporated collagen tubes. Brain Res. 2003 Dec 12/12/2003; 993(1-2): 208-16. PMID: 14642848, PII: S0006899303036394, ISSN: 0006-8993.
Gomathi K, Gopinath D, Rafiuddin Ahmed M, Jayakumar R. Quercetin incorporated collagen matrices for dermal wound healing processes in rat. Biomaterials. 2003 Jul; 24(16): 2767-72. PMID: 12711523, PII: S0142961203000590, ISSN: 0142-9612.
Jayakumar R, Murugesan M, Ahmed MR. Formation of multilamellar vesicles ('onions') in peptide based surfactant. Bioorg. Med. Chem. Lett. 2000 Jul 7/17/2000; 10(14): 1547-50. PMID: 10915047, PII: S0960-894X(00)00289-4, ISSN: 0960-894X.
Bychkov E, Ahmed MR, Gurevich EV. Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia. Int. J. Neuropsychopharmacol [print-electronic]. 2011 Feb; 14(1): 1-15. PMID: 20158934, PMCID: PMC2992801, PII: S1461145710000118, DOI: 10.1017/S1461145710000118, ISSN: 1469-5111.
Ahmed MR, Berthet A, Bychkov E, Porras G, Li Q, Bioulac BH, Carl YT, Bloch B, Kook S, Aubert I, Dovero S, Doudnikoff E, Gurevich VV, Gurevich EV, Bezard E. Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease. Sci Transl Med. 2010 Apr 4/21/2010; 2(28): 28ra28. PMID: 20410529, PMCID: PMC2933751, PII: 2/28/28ra28, DOI: 10.1126/scitranslmed.3000664, ISSN: 1946-6242.
Ahmed MR, Gurevich VV, Dalby KN, Benovic JL, Gurevich EV. Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation. J. Pharmacol. Exp. Ther [print-electronic]. 2008 Apr; 325(1): 276-83. PMID: 18178904, PMCID: PMC2629350, PII: jpet.107.131987, DOI: 10.1124/jpet.107.131987, ISSN: 1521-0103.
Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment. J. Neurochem [print-electronic]. 2008 Mar; 104(6): 1622-36. PMID: 17996024, PMCID: PMC2628845, PII: JNC5104, DOI: 10.1111/j.1471-4159.2007.05104.x, ISSN: 1471-4159.
Bychkov E, Ahmed MR, Dalby KN, Gurevich EV. Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum. J. Neurochem. 2007 Aug; 102(3): 699-711. PMID: 17630981, PII: JNC4586, DOI: 10.1111/j.1471-4159.2007.04586.x, ISSN: 0022-3042.
Hanson SM, Gurevich EV, Vishnivetskiy SA, Ahmed MR, Song X, Gurevich VV. Each rhodopsin molecule binds its own arrestin. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2007 Feb 2/27/2007; 104(9): 3125-8. PMID: 17360618, PMCID: PMC1805568, PII: 0610886104, DOI: 10.1073/pnas.0610886104, ISSN: 0027-8424.
Sripriya R, Kumar MS, Ahmed MR, Sehgal PK. Collagen bilayer dressing with ciprofloxacin, an effective system for infected wound healing. J Biomater Sci Polym Ed. 2007; 18(3): 335-51. PMID: 17471769, ISSN: 0920-5063.
Dhanaraju MD, Gopinath D, Ahmed MR, Jayakumar R, Vamsadhara C. Characterization of polymeric poly(epsilon-caprolactone) injectable implant delivery system for the controlled delivery of contraceptive steroids. J Biomed Mater Res A. 2006 Jan; 76(1): 63-72. PMID: 16108044, DOI: 10.1002/jbm.a.30458, ISSN: 1549-3296.
Ahmed MR, Jayakumar R. Peripheral nerve regeneration in cell adhesive peptide incorporated collagen tubes in rat sciatic nerve -- early and better functional regain [letter]. J. Peripher. Nerv. Syst. 2005 Dec; 10(4): 390-1. PMID: 16279992, PII: JNS055, DOI: 10.1111/j.1085-9489.2005.00055.x, ISSN: 1085-9489.
Ahmed MR, Vairamuthu S, Shafiuzama M, Basha SH, Jayakumar R. Microwave irradiated collagen tubes as a better matrix for peripheral nerve regeneration. Brain Res. 2005 Jun 6/7/2005; 1046(1-2): 55-67. PMID: 15927550, PII: S0006-8993(05)00444-0, DOI: 10.1016/j.brainres.2005.03.022, ISSN: 0006-8993.
Ahmed MR, Basha SH, Gopinath D, Muthusamy R, Jayakumar R. Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. J. Peripher. Nerv. Syst. 2005 Mar; 10(1): 17-30. PMID: 15703015, PII: JNS10105, DOI: 10.1111/j.1085-9489.2005.10105.x, ISSN: 1085-9489.
Ahmed MR, Venkateshwarlu U, Jayakumar R. Multilayered peptide incorporated collagen tubules for peripheral nerve repair. Biomaterials. 2004 Jun; 25(13): 2585-94. PMID: 14751744, PII: S0142961203007683, ISSN: 0142-9612.
Ahmed MR, Gopinath D, Gomathi K, Sehgal PK, Jayakumar R. Alpha-crystallin-incorporated collagen matrices as an aid for dermal wound healing. J. Biomed. Mater. Res. Part B Appl. Biomater. 2004 May 5/15/2004; 69(2): 241-8. PMID: 15116414, DOI: 10.1002/jbm.b.30003, ISSN: 1552-4973.
Gopinath D, Ahmed MR, Gomathi K, Chitra K, Sehgal PK, Jayakumar R. Dermal wound healing processes with curcumin incorporated collagen films. Biomaterials. 2004 May; 25(10): 1911-7. PMID: 14738855, PII: S0142961203006252, ISSN: 0142-9612.
Rafiuddin Ahmed M, Jayakumar R. Peripheral nerve regeneration in RGD peptide incorporated collagen tubes. Brain Res. 2003 Dec 12/12/2003; 993(1-2): 208-16. PMID: 14642848, PII: S0006899303036394, ISSN: 0006-8993.
Gomathi K, Gopinath D, Rafiuddin Ahmed M, Jayakumar R. Quercetin incorporated collagen matrices for dermal wound healing processes in rat. Biomaterials. 2003 Jul; 24(16): 2767-72. PMID: 12711523, PII: S0142961203000590, ISSN: 0142-9612.
Jayakumar R, Murugesan M, Ahmed MR. Formation of multilamellar vesicles ('onions') in peptide based surfactant. Bioorg. Med. Chem. Lett. 2000 Jul 7/17/2000; 10(14): 1547-50. PMID: 10915047, PII: S0960-894X(00)00289-4, ISSN: 0960-894X.