Nicholas Ferrell, Ph.D.

Assistant Professor
Faculty Appointments
Assistant Professor of Medicine Assistant Professor of Biomedical Engineering
Ph.D., BIOMEDICAL ENGINEERING, Ohio State University, Columbus, OhioB.S., MECHANICAL ENGINEERING, Ohio State University, Columbus, Ohio
Office Address
1161 21st Avenue South
Nashville , TN 37232
Howard AM, LaFever KS, Fenix AM, Scurrah CR, Lau KS, Burnette DT, Bhave G, Ferrell N, Page-McCaw A. DSS-induced damage to basement membranes is repaired by matrix replacement and crosslinking. J. Cell. Sci [print-electronic]. 2019 Mar 3/5/2019; PMID: 30837285, PII: jcs.226860, DOI: 10.1242/jcs.226860, ISSN: 1477-9137.

Love HD, Ao M, Jorgensen S, Swearingen L, Ferrell NJ, Evans RC, Gewin L, Harris RC, Zent R, Roy S, Fissell WH. Substrate Elasticity Governs Differentiation of Renal Tubule Cells in Prolonged Culture. Tissue Eng Part A [print-electronic]. 2018 Nov 11/28/2018; PMID: 30484388, DOI: 10.1089/ten.TEA.2018.0182, ISSN: 1937-335X.

Ferrell N, Cheng J, Miao S, Roy S, Fissell WH. Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells. ASAIO J. 2017 Dec; 64(6): 766-72. PMID: 29240625, PMCID: PMC5995603, DOI: 10.1097/MAT.0000000000000723, ISSN: 1538-943X.

Bhave G, Colon S, Ferrell N. The sulfilimine cross-link of collagen IV contributes to kidney tubular basement membrane stiffness. Am. J. Physiol. Renal Physiol [print-electronic]. 2017 Sep 9/1/2017; 313(3): F596-F602. PMID: 28424209, PMCID: PMC5625101, PII: ajprenal.00096.2017, DOI: 10.1152/ajprenal.00096.2017, ISSN: 1522-1466.

Brakeman P, Miao S, Cheng J, Lee CZ, Roy S, Fissell WH, Ferrell N. A modular microfluidic bioreactor with improved throughput for evaluation of polarized renal epithelial cells. Biomicrofluidics. 2016 Nov; 10(6): 64106. PMID: 27917253, PMCID: PMC5116024, PII: 003606BMF, PII: 1.4966986, DOI: 10.1063/1.4966986, ISSN: 1932-1058.

Ferrell N, Sandoval RM, Bian A, Campos-Bilderback SB, Molitoris BA, Fissell WH. Shear stress is normalized in glomerular capillaries following ¿ nephrectomy. Am. J. Physiol. Renal Physiol [print-electronic]. 2015 Mar 3/15/2015; 308(6): F588-93. PMID: 25587117, PMCID: PMC4360039, PII: ajprenal.00290.2014, DOI: 10.1152/ajprenal.00290.2014, ISSN: 1522-1466.

Ferrell N, Cameron KO, Groszek JJ, Hofmann CL, Li L, Smith RA, Bian A, Shintani A, Zydney AL, Fissell WH. Effects of pressure and electrical charge on macromolecular transport across bovine lens basement membrane. Biophys. J. 2013 Apr 4/2/2013; 104(7): 1476-84. PMID: 23561524, PMCID: PMC3617438, PII: S0006-3495(13)00261-0, DOI: 10.1016/j.bpj.2013.01.062, ISSN: 1542-0086.

Zhang B, Romaker D, Ferrell N, Wessely O. Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros. Dev. Biol [print-electronic]. 2013 Apr 4/1/2013; 376(1): 31-42. PMID: 23352791, PMCID: PMC3767149, PII: S0012-1606(13)00035-3, DOI: 10.1016/j.ydbio.2013.01.017, ISSN: 1095-564X.

Ferrell N, Ricci KB, Groszek J, Marmerstein JT, Fissell WH. Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor. Biotechnol. Bioeng [print-electronic]. 2012 Mar; 109(3): 797-803. PMID: 22012446, PMCID: PMC3285552, DOI: 10.1002/bit.24339, ISSN: 1097-0290.

Ferrell N, Groszek J, Li L, Smith R, Butler RS, Zorman CA, Roy S, Fissell WH. Basal lamina secreted by MDCK cells has size- and charge-selective properties. Am. J. Physiol. Renal Physiol [print-electronic]. 2011 Jan; 300(1): F86-90. PMID: 20980405, PMCID: PMC3023222, PII: ajprenal.00484.2010, DOI: 10.1152/ajprenal.00484.2010, ISSN: 1522-1466.

Pelaez-Vargas A, Gallego-Perez D, Ferrell N, Fernandes MH, Hansford D, Monteiro FJ. Early spreading and propagation of human bone marrow stem cells on isotropic and anisotropic topographies of silica thin films produced via microstamping. Microsc. Microanal [print-electronic]. 2010 Dec; 16(6): 670-6. PMID: 20964878, PII: S1431927610094158, DOI: 10.1017/S1431927610094158, ISSN: 1435-8115.

Gallego-Perez D, Ferrell NJ, Higuita-Castro N, Hansford DJ. Versatile methods for the fabrication of polyvinylidene fluoride microstructures. Biomed Microdevices. 2010 Dec; 12(6): 1009-17. PMID: 20700656, DOI: 10.1007/s10544-010-9455-9, ISSN: 1572-8781.

Ferrell N, Desai RR, Fleischman AJ, Roy S, Humes HD, Fissell WH. A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells. Biotechnol. Bioeng. 2010 Nov 11/1/2010; 107(4): 707-16. PMID: 20552673, PMCID: PMC3903011, DOI: 10.1002/bit.22835, ISSN: 1097-0290.

Groszek J, Li L, Ferrell N, Smith R, Zorman CA, Hofmann CL, Roy S, Fissell WH. Molecular conformation and filtration properties of anionic Ficoll. Am. J. Physiol. Renal Physiol [print-electronic]. 2010 Oct; 299(4): F752-7. PMID: 20668097, PII: ajprenal.00324.2010, DOI: 10.1152/ajprenal.00324.2010, ISSN: 1522-1466.

Ferrell N, Gallego-Perez D, Higuita-Castro N, Butler RT, Reen RK, Gooch KJ, Hansford DJ. Vacuum-assisted cell seeding in a microwell cell culture system. Anal. Chem. 2010 Mar 3/15/2010; 82(6): 2380-6. PMID: 20180539, DOI: 10.1021/ac902596b, ISSN: 1520-6882.

Fissell WH, Hofmann CL, Ferrell N, Schnell L, Dubnisheva A, Zydney AL, Yurchenco PD, Roy S. Solute partitioning and filtration by extracellular matrices. Am. J. Physiol. Renal Physiol [print-electronic]. 2009 Oct; 297(4): F1092-100. PMID: 19587146, PMCID: PMC2775571, PII: 00162.2009, DOI: 10.1152/ajprenal.00162.2009, ISSN: 1522-1466.

Schwan S, Ferrell N, Hansford D, Spohn U, Heilmann A. Measurement of mechanical forces generated by plant P-protein aggregates (forisomes). Eur. Biophys. J [print-electronic]. 2009 Apr; 38(4): 533-6. PMID: 19002454, DOI: 10.1007/s00249-008-0382-0, ISSN: 1432-1017.

Ferrell N, Woodard J, Hansford D. Fabrication of polymer microstructures for MEMS: sacrificial layer micromolding and patterned substrate micromolding. Biomed Microdevices. 2007 Dec; 9(6): 815-21. PMID: 17564840, DOI: 10.1007/s10544-007-9094-y, ISSN: 1387-2176.