Georgia L. Wiesner, M.D.

Professor

georgia.wiesner@vanderbilt.edu
Faculty Appointments
Professor of Medicine Ingram Professor of Cancer Research
Education
M.D., MEDICINE M D, University of Minnesota, Minneapolis, MinnesotaM.S., GENETICS M S, University of Minnesota, Minneapolis, MinnesotaB.A., University of Northern Colorado, Greeley, Colorado
Publications
Schneider JL, Davis J, Kauffman TL, Reiss JA, McGinley C, Arnold K, Zepp J, Gilmore M, Muessig KR, Syngal S, Acheson L, Wiesner GL, Peterson SK, Goddard KA. Stakeholder perspectives on implementing a universal Lynch syndrome screening program: a qualitative study of early barriers and facilitators. Genet. Med [print-electronic]. 2016 Feb; 18(2): 152-61. PMID: 25880440, PMCID: PMC4608844, PII: gim201543, DOI: 10.1038/gim.2015.43, ISSN: 1530-0366.

Daly MB, Pilarski R, Axilbund JE, Berry M, Buys SS, Crawford B, Farmer M, Friedman S, Garber JE, Khan S, Klein C, Kohlmann W, Kurian A, Litton JK, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Rana H, Reiser G, Robson ME, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wick MJ, Wiesner GL, Dwyer M, Kumar R, Darlow S. Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015. J Natl Compr Canc Netw. 2016 Feb; 14(2): 153-62. PMID: 26850485, PII: 14/2/153, ISSN: 1540-1413.

Hunter JE, Zepp JM, Gilmore MJ, Davis JV, Esterberg EJ, Muessig KR, Peterson SK, Syngal S, Acheson LS, Wiesner GL, Reiss JA, Goddard KA. Universal tumor screening for Lynch syndrome: Assessment of the perspectives of patients with colorectal cancer regarding benefits and barriers. Cancer [print-electronic]. 2015 Sep 9/15/2015; 121(18): 3281-9. PMID: 26036338, PMCID: PMC4560979, DOI: 10.1002/cncr.29470, ISSN: 1097-0142.

Hampel H, Bennett RL, Buchanan A, Pearlman R, Wiesner GL, . A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. Genet. Med [print-electronic]. 2015 Jan; 17(1): 70-87. PMID: 25394175, PII: gim2014147, DOI: 10.1038/gim.2014.147.

Hall MJ, Forman AD, Pilarski R, Wiesner G, Giri VN. Gene panel testing for inherited cancer risk. J Natl Compr Canc Netw. 2014 Sep; 12(9): 1339-46. PMID: 25190699, PII: 12/9/1339, ISSN: 1540-1413.

Daly MB, Pilarski R, Axilbund JE, Buys SS, Crawford B, Friedman S, Garber JE, Horton C, Kaklamani V, Klein C, Kohlmann W, Kurian A, Litton J, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Pasche B, Reiser G, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wiesner GL, Dwyer MA, Kumar R, . Genetic/familial high-risk assessment: breast and ovarian, version 1.2014. J Natl Compr Canc Netw. 2014 Sep; 12(9): 1326-38. PMID: 25190698, PII: 12/9/1326.

Guda K, Fink SP, Milne GL, Molyneaux N, Ravi L, Lewis SM, Dannenberg AJ, Montgomery CG, Zhang S, Willis J, Wiesner GL, Markowitz SD. Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance. Cancer Prev Res (Phila) [print-electronic]. 2014 Aug; 7(8): 805-12. PMID: 24838973, PMCID: PMC4125515, PII: 1940-6207.CAPR-14-0108, DOI: 10.1158/1940-6207.CAPR-14-0108, ISSN: 1940-6215.

Edwards KL, Lemke AA, Trinidad SB, Lewis SM, Starks H, Snapinn KW, Griffin MQ, Wiesner GL, Burke W, . Genetics researchers' and IRB professionals' attitudes toward genetic research review: a comparative analysis. Genet. Med [print-electronic]. 2012 Feb; 14(2): 236-42. PMID: 22241102, PMCID: PMC3448270, PII: gim201157, DOI: 10.1038/gim.2011.57, ISSN: 1530-0366.

Dressler LG, Smolek S, Ponsaran R, Markey JM, Starks H, Gerson N, Lewis S, Press N, Juengst E, Wiesner GL, . IRB perspectives on the return of individual results from genomic research. Genet. Med [print-electronic]. 2012 Feb; 14(2): 215-22. PMID: 22241094, PMCID: PMC3493147, PII: gim201110, DOI: 10.1038/gim.2011.10, ISSN: 1530-0366.

Gray-McGuire C, Guda K, Adrianto I, Lin CP, Natale L, Potter JD, Newcomb P, Poole EM, Ulrich CM, Lindor N, Goode EL, Fridley BL, Jenkins R, Le Marchand L, Casey G, Haile R, Hopper J, Jenkins M, Young J, Buchanan D, Gallinger S, Adams M, Lewis S, Willis J, Elston R, Markowitz SD, Wiesner GL. Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22. Cancer Res [print-electronic]. 2010 Jul 7/1/2010; 70(13): 5409-18. PMID: 20551049, PMCID: PMC2896448, PII: 0008-5472.CAN-10-0188, DOI: 10.1158/0008-5472.CAN-10-0188, ISSN: 1538-7445.

, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J, Rao TS, Remacle J, Schafer AJ, Shibata T, Stratton MR, Vockley JG, Watanabe K, Yang H, Yuen MM, Knoppers BM, Bobrow M, Cambon-Thomsen A, Dressler LG, Dyke SO, Joly Y, Kato K, Kennedy KL, Nicolás P, Parker MJ, Rial-Sebbag E, Romeo-Casabona CM, Shaw KM, Wallace S, Wiesner GL, Zeps N, Lichter P, Biankin AV, Chabannon C, Chin L, Clément B, de Alava E, Degos F, Ferguson ML, Geary P, Hayes DN, Hudson TJ, Johns AL, Kasprzyk A, Nakagawa H, Penny R, Piris MA, Sarin R, Scarpa A, Shibata T, van de Vijver M, Futreal PA, Aburatani H, Bayés M, Botwell DD, Campbell PJ, Estivill X, Gerhard DS, Grimmond SM, Gut I, Hirst M, López-Otín C, Majumder P, Marra M, McPherson JD, Nakagawa H, Ning Z, Puente XS, Ruan Y, Shibata T, Stratton MR, Stunnenberg HG, Swerdlow H, Velculescu VE, Wilson RK, Xue HH, Yang L, Spellman PT, Bader GD, Boutros PC, Campbell PJ, Flicek P, Getz G, Guigó R, Guo G, Haussler D, Heath S, Hubbard TJ, Jiang T, Jones SM, Li Q, López-Bigas N, Luo R, Muthuswamy L, Ouellette BF, Pearson JV, Puente XS, Quesada V, Raphael BJ, Sander C, Shibata T, Speed TP, Stein LD, Stuart JM, Teague JW, Totoki Y, Tsunoda T, Valencia A, Wheeler DA, Wu H, Zhao S, Zhou G, Stein LD, Guigó R, Hubbard TJ, Joly Y, Jones SM, Kasprzyk A, Lathrop M, López-Bigas N, Ouellette BF, Spellman PT, Teague JW, Thomas G, Valencia A, Yoshida T, Kennedy KL, Axton M, Dyke SO, Futreal PA, Gerhard DS, Gunter C, Guyer M, Hudson TJ, McPherson JD, Miller LJ, Ozenberger B, Shaw KM, Kasprzyk A, Stein LD, Zhang J, Haider SA, Wang J, Yung CK, Cros A, Liang Y, Gnaneshan S, Guberman J, Hsu J, Bobrow M, Chalmers DR, Hasel KW, Joly Y, Kaan TS, Kennedy KL, Knoppers BM, Lowrance WW, Masui T, Nicolás P, Rial-Sebbag E, Rodriguez LL, Vergely C, Yoshida T, Grimmond SM, Biankin AV, Bowtell DD, Cloonan N, deFazio A, Eshleman JR, Etemadmoghadam D, Gardiner BB, Kench JG, Scarpa A, Sutherland RL, Tempero MA, Waddell NJ, Wilson PJ, McPherson JD, Gallinger S, Tsao MS, Shaw PA, Petersen GM, Mukhopadhyay D, Chin L, DePinho RA, Thayer S, Muthuswamy L, Shazand K, Beck T, Sam M, Timms L, Ballin V, Lu Y, Ji J, Zhang X, Chen F, Hu X, Zhou G, Yang Q, Tian G, Zhang L, Xing X, Li X, Zhu Z, Yu Y, Yu J, Yang H, Lathrop M, Tost J, Brennan P, Holcatova I, Zaridze D, Brazma A, Egevard L, Prokhortchouk E, Banks RE, Uhlén M, Cambon-Thomsen A, Viksna J, Ponten F, Skryabin K, Stratton MR, Futreal PA, Birney E, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Martin S, Reis-Filho JS, Richardson AL, Sotiriou C, Stunnenberg HG, Thoms G, van de Vijver M, van't Veer L, Calvo F, Birnbaum D, Blanche H, Boucher P, Boyault S, Chabannon C, Gut I, Masson-Jacquemier JD, Lathrop M, Pauporté I, Pivot X, Vincent-Salomon A, Tabone E, Theillet C, Thomas G, Tost J, Treilleux I, Calvo F, Bioulac-Sage P, Clément B, Decaens T, Degos F, Franco D, Gut I, Gut M, Heath S, Lathrop M, Samuel D, Thomas G, Zucman-Rossi J, Lichter P, Eils R, Brors B, Korbel JO, Korshunov A, Landgraf P, Lehrach H, Pfister S, Radlwimmer B, Reifenberger G, Taylor MD, von Kalle C, Majumder PP, Sarin R, Rao TS, Bhan MK, Scarpa A, Pederzoli P, Lawlor RA, Delledonne M, Bardelli A, Biankin AV, Grimmond SM, Gress T, Klimstra D, Zamboni G, Shibata T, Nakamura Y, Nakagawa H, Kusada J, Tsunoda T, Miyano S, Aburatani H, Kato K, Fujimoto A, Yoshida T, Campo E, López-Otín C, Estivill X, Guigó R, de Sanjosé S, Piris MA, Montserrat E, González-Díaz M, Puente XS, Jares P, Valencia A, Himmelbauer H, Quesada V, Bea S, Stratton MR, Futreal PA, Campbell PJ, Vincent-Salomon A, Richardson AL, Reis-Filho JS, van de Vijver M, Thomas G, Masson-Jacquemier JD, Aparicio S, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Stunnenberg HG, van't Veer L, Easton DF, Spellman PT, Martin S, Barker AD, Chin L, Collins FS, Compton CC, Ferguson ML, Gerhard DS, Getz G, Gunter C, Guttmacher A, Guyer M, Hayes DN, Lander ES, Ozenberger B, Penny R, Peterson J, Sander C, Shaw KM, Speed TP, Spellman PT, Vockley JG, Wheeler DA, Wilson RK, Hudson TJ, Chin L, Knoppers BM, Lander ES, Lichter P, Stein LD, Stratton MR, Anderson W, Barker AD, Bell C, Bobrow M, Burke W, Collins FS, Compton CC, DePinho RA, Easton DF, Futreal PA, Gerhard DS, Green AR, Guyer M, Hamilton SR, Hubbard TJ, Kallioniemi OP, Kennedy KL, Ley TJ, Liu ET, Lu Y, Majumder P, Marra M, Ozenberger B, Peterson J, Schafer AJ, Spellman PT, Stunnenberg HG, Wainwright BJ, Wilson RK, Yang H. International network of cancer genome projects. Nature. 2010 Apr 4/15/2010; 464(7291): 993-8. PMID: 20393554, PMCID: PMC2902243, PII: nature08987, DOI: 10.1038/nature08987, ISSN: 1476-4687.

Lemke AA, Trinidad SB, Edwards KL, Starks H, Wiesner GL, . Attitudes toward genetic research review: results from a national survey of professionals involved in human subjects protection. J Empir Res Hum Res Ethics. 2010 Mar; 5(1): 83-91. PMID: 20235866, PMCID: PMC2902178, DOI: 10.1525/jer.2010.5.1.83, ISSN: 1556-2646.

Slavin TP, Wiesner GL. Developmental defects and childhood cancer. Curr. Opin. Pediatr. 2009 Dec; 21(6): 717-23. PMID: 19812499, DOI: 10.1097/MOP.0b013e328332c612, ISSN: 1531-698X.

Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JK, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, Velculescu VE, Kinzler KW, Papadopoulos N, Vogelstein B, Willis J, Gerken TA, Markowitz SD. Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2009 Aug 8/4/2009; 106(31): 12921-5. PMID: 19617566, PMCID: PMC2722285, PII: 0901454106, DOI: 10.1073/pnas.0901454106, ISSN: 1091-6490.

Guda K, Natale L, Lutterbaugh J, Wiesner GL, Lewis S, Tanner SM, Tomsic J, Valle L, de la Chapelle A, Elston RC, Willis J, Markowitz SD. Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res [print-electronic]. 2009 Jun 6/15/2009; 69(12): 4959-61. PMID: 19509225, PMCID: PMC2739986, PII: 0008-5472.CAN-09-0225, DOI: 10.1158/0008-5472.CAN-09-0225, ISSN: 1538-7445.

Simon C, Acheson L, Burant C, Gerson N, Schramm S, Lewis S, Wiesner G. Patient interest in recording family histories of cancer via the Internet. Genet. Med. 2008 Dec; 10(12): 895-902. PMID: 19092442, PMCID: PMC3342847, PII: 00125817-200812000-00006, DOI: 10.1097/GIM.0b013e31818de708, ISSN: 1530-0366.

Daley D, Lewis S, Platzer P, MacMillen M, Willis J, Elston RC, Markowitz SD, Wiesner GL. Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. Am. J. Hum. Genet [print-electronic]. 2008 Mar; 82(3): 723-36. PMID: 18313025, PMCID: PMC2427227, PII: S0002-9297(08)00137-7, DOI: 10.1016/j.ajhg.2008.01.007, ISSN: 1537-6605.

Ochs-Balcom HM, Wiesner G, Elston RC. A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer. Am. J. Epidemiol [print-electronic]. 2007 Aug 8/1/2007; 166(3): 246-54. PMID: 17535831, PII: kwm066, DOI: 10.1093/aje/kwm066, ISSN: 0002-9262.

Daley D, Morgan W, Lewis S, Willis J, Elston RC, Markowitz SD, Wiesner GL. Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?. Cancer Epidemiol. Biomarkers Prev. 2007 May; 16(5): 892-4. PMID: 17507611, PII: 16/5/892, DOI: 10.1158/1055-9965.EPI-06-0965, ISSN: 1055-9965.

Nosek TM, Cohen M, Matthews A, Papp K, Wolf N, Wrenn G, Sher A, Coulter K, Martin J, Wiesner GL. A serious gaming/immersion environment to teach clinical cancer genetics. Stud Health Technol Inform. 2007; 125: 355-60. PMID: 17377303, ISSN: 0926-9630.

Acheson LS, Zyzanski SJ, Stange KC, Deptowicz A, Wiesner GL. Validation of a self-administered, computerized tool for collecting and displaying the family history of cancer. J. Clin. Oncol [print-electronic]. 2006 Dec 12/1/2006; 24(34): 5395-402. PMID: 17088568, PII: JCO.2006.07.2462, DOI: 10.1200/JCO.2006.07.2462, ISSN: 1527-7755.

Korf BR, Feldman G, Wiesner GL. Report of Banbury Summit meeting on training of physicians in medical genetics, October 20-22, 2004. Genet. Med. 2005 Jul; 7(6): 433-8. PMID: 16024976, PII: 00125817-200507000-00009, DOI: 10.109701.GIM.0000171324.58121.CF, ISSN: 1098-3600.

Chak A, Faulx A, Kinnard M, Brock W, Willis J, Wiesner GL, Parrado AR, Goddard KA. Identification of Barrett's esophagus in relatives by endoscopic screening. Am. J. Gastroenterol. 2004 Nov; 99(11): 2107-14. PMID: 15554988, PII: AJG40464, DOI: 10.1111/j.1572-0241.2004.40464.x, ISSN: 0002-9270.

Matthews AL, Grimes SJ, Wiesner GL, Acheson LS. Clinical consult: iron overload--hereditary hemochromatosis. Prim. Care. 2004 Sep; 31(3): 767-70, xii. PMID: 15331258, PII: S0095454304000508, DOI: 10.1016/j.pop.2004.04.007, ISSN: 0095-4543.

Grimes SJ, Acheson LS, Matthews AL, Wiesner GL. Clinical consult: Marfan syndrome. Prim. Care. 2004 Sep; 31(3): 739-42, xii. PMID: 15331256, PII: S009545430400048X, DOI: 10.1016/j.pop.2004.04.005, ISSN: 0095-4543.

Culler D, Grimes SJ, Acheson LS, Wiesner GL. Cancer genetics in primary care. Prim. Care. 2004 Sep; 31(3): 649-83, xi. PMID: 15331253, PII: S0095454304000612, DOI: 10.1016/j.pop.2004.05.001, ISSN: 0095-4543.

Wiesner GL, Cassidy SB, Grimes SJ, Matthews AL, Acheson LS. Clinical consult: developmental delay/fragile X syndrome. Prim. Care. 2004 Sep; 31(3): 621-5, x. PMID: 15331251, PII: S009545430400051X, DOI: 10.1016/j.pop.2004.04.008, ISSN: 0095-4543.

Acheson LS, Wiesner GL. Current and future applications of genetics in primary care medicine. Prim. Care. 2004 Sep; 31(3): 449-60, vii. PMID: 15331241, PII: S009545430400065X, DOI: 10.1016/j.pop.2004.05.002, ISSN: 0095-4543.

Wiesner GL, Daley D, Lewis S, Ticknor C, Platzer P, Lutterbaugh J, MacMillen M, Baliner B, Willis J, Elston RC, Markowitz SD. A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2003 Oct 10/28/2003; 100(22): 12961-5. PMID: 14566058, PMCID: PMC240727, PII: 2132286100, DOI: 10.1073/pnas.2132286100, ISSN: 0027-8424.

Dugan RB, Wiesner GL, Juengst ET, O'Riordan M, Matthews AL, Robin NH. Duty to warn at-risk relatives for genetic disease: genetic counselors' clinical experience. Am J Med Genet C Semin Med Genet. 2003 May 5/15/2003; 119C(1): 27-34. PMID: 12704635, DOI: 10.1002/ajmg.c.10005, ISSN: 1552-4868.

Burke W, Atkins D, Gwinn M, Guttmacher A, Haddow J, Lau J, Palomaki G, Press N, Richards CS, Wideroff L, Wiesner GL. Genetic test evaluation: information needs of clinicians, policy makers, and the public. Am. J. Epidemiol. 2002 Aug 8/15/2002; 156(4): 311-8. PMID: 12181100, ISSN: 0002-9262.