Xingyi Guo, Ph.D.

Assistant Professor

xingyi.guo@vanderbilt.edu
Faculty Appointments
Assistant Professor of Medicine
Education
Ph.D., Zhejiang University, Hangzhou, ChinaB.S., Anhui Science and Technology University, Anhui, Foreign, China
Office Address
2525 West End Suite 600
Nashville, TN 37203
Research Keywords
Bioinformatics, functional genomics, epigenetics, genetic epidemiology, cancer research
Publications
Wang S, Beeghly-Fadiel A, Cai Q, Cai H, Guo X, Shi L, Wu J, Ye F, Qiu Q, Zheng Y, Zheng W, Bao PP, Shu XO. Gene expression in triple-negative breast cancer in relation to survival. Breast Cancer Res. Treat [print-electronic]. 2018 May 5/10/2018; PMID: 29748761, PII: 10.1007/s10549-018-4816-9, DOI: 10.1007/s10549-018-4816-9, ISSN: 1573-7217.

Guo X, Lin W, Bao J, Cai Q, Pan X, Bai M, Yuan Y, Shi J, Sun Y, Han MR, Wang J, Liu Q, Wen W, Li B, Long J, Chen J, Zheng W. A Comprehensive cis-eQTL Analysis Revealed Target Genes in Breast Cancer Susceptibility Loci Identified in Genome-wide Association Studies. Am. J. Hum. Genet. 2018 May 5/3/2018; 102(5): 890-903. PMID: 29727689, PII: S0002-9297(18)30105-8, DOI: 10.1016/j.ajhg.2018.03.016, ISSN: 1537-6605.

Liu M, Zhu J, Wu S, Wang C, Guo X, Wu J, Zhou M. De novo assembly and analysis of the Artemisia argyi transcriptome and identification of genes involved in terpenoid biosynthesis. Sci Rep. 2018 Apr 4/11/2018; 8(1): 5824. PMID: 29643397, PMCID: PMC5895812, PII: 10.1038/s41598-018-24201-9, DOI: 10.1038/s41598-018-24201-9, ISSN: 2045-2322.

Guo X, Shi J, Cai Q, Shu XO, He J, Wen W, Allen J, Pharoah P, Dunning A, Hunter DJ, Kraft P, Easton DF, Zheng W, Long J. Use of deep whole-genome sequencing data to identify structure risk variants in breast cancer susceptibility genes. Hum. Mol. Genet. 2018 Mar 3/1/2018; 27(5): 853-9. PMID: 29325031, PII: 4793000, DOI: 10.1093/hmg/ddy005, ISSN: 1460-2083.

Seki Y, Suzuki M, Guo X, Glenn AS, Vuguin PM, Fiallo A, Du Q, Ko YA, Yu Y, Susztak K, Zheng D, Greally JM, Katz EB, Charron MJ. In Utero Exposure to a High-Fat Diet Programs Hepatic Hypermethylation and Gene Dysregulation and Development of Metabolic Syndrome in Male Mice. Endocrinology. 2017 Sep 9/1/2017; 158(9): 2860-72. PMID: 28911167, PMCID: PMC5659663, PII: 3882533, DOI: 10.1210/en.2017-00334, ISSN: 1945-7170.

Wen W, Shu XO, Guo X, Cai Q, Long J, Bolla MK, Michailidou K, Dennis J, Wang Q, Gao YT, Zheng Y, Dunning AM, García-Closas M, Brennan P, Chen ST, Choi JY, Hartman M, Ito H, Lophatananon A, Matsuo K, Miao H, Muir K, Sangrajrang S, Shen CY, Teo SH, Tseng CC, Wu AH, Yip CH, Simard J, Pharoah PD, Hall P, Kang D, Xiang Y, Easton DF, Zheng W. Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry. Breast Cancer Res. 2016 Dec 12/8/2016; 18(1): 124. PMID: 27931260, PMCID: PMC5146840, PII: 10.1186/s13058-016-0786-1, DOI: 10.1186/s13058-016-0786-1, ISSN: 1465-542X.

Zhang Y, Wagner EK, Guo X, May I, Cai Q, Zheng W, He C, Long J. Long intergenic non-coding RNA expression signature in human breast cancer. Sci Rep. 2016 Nov 11/29/2016; 6: 37821. PMID: 27897201, PMCID: PMC5126689, PII: srep37821, DOI: 10.1038/srep37821, ISSN: 2045-2322.

Johnson DB, Frampton GM, Rioth MJ, Yusko E, Xu Y, Guo X, Ennis RC, Fabrizio D, Chalmers ZR, Greenbowe J, Ali SM, Balasubramanian S, Sun JX, He Y, Frederick DT, Puzanov I, Balko JM, Cates JM, Ross JS, Sanders C, Robins H, Shyr Y, Miller VA, Stephens PJ, Sullivan RJ, Sosman JA, Lovly CM. Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade. Cancer Immunol Res [print-electronic]. 2016 Nov; 4(11): 959-67. PMID: 27671167, PMCID: PMC5134329, PII: 2326-6066.CIR-16-0143, DOI: 10.1158/2326-6066.CIR-16-0143, ISSN: 2326-6074.

Shi J, Zhang Y, Zheng W, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Dennis J, Lush M, Milne RL, Shu XO, Beesley J, Kar S, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Zhao Z, Guo X, Benitez J, Beeghly-Fadiel A, Blot W, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Brinton L, Broeks A, Brüning T, Burwinkel B, Cai H, Canisius S, Chang-Claude J, Choi JY, Couch FJ, Cox A, Cross SS, Czene K, Darabi H, Devilee P, Droit A, Dork T, Fasching PA, Fletcher O, Flyger H, Fostira F, Gaborieau V, García-Closas M, Giles GG, Grip M, Guenel P, Haiman CA, Hamann U, Hartman M, Miao H, Hollestelle A, Hopper JL, Hsiung CN, , Ito H, Jakubowska A, Johnson N, Torres D, Kabisch M, Kang D, Khan S, Knight JA, Kosma VM, Lambrechts D, Li J, Lindblom A, Lophatananon A, Lubinski J, Mannermaa A, Manoukian S, Le Marchand L, Margolin S, Marme F, Matsuo K, McLean C, Meindl A, Muir K, Neuhausen SL, Nevanlinna H, Nord S, Børresen-Dale AL, Olson JE, Orr N, van den Ouweland AM, Peterlongo P, Choudary Putti T, Rudolph A, Sangrajrang S, Sawyer EJ, Schmidt MK, Schmutzler RK, Shen CY, Hou MF, Shrubsole MJ, Southey MC, Swerdlow A, Hwang Teo S, Thienpont B, Toland AE, Tollenaar RA, Tomlinson I, Truong T, Tseng CC, Wen W, Winqvist R, Wu AH, Har Yip C, Zamora PM, Zheng Y, Floris G, Cheng CY, Hooning MJ, Martens JW, Seynaeve C, Kristensen VN, Hall P, Pharoah PD, Simard J, Chenevix-Trench G, Dunning AM, Antoniou AC, Easton DF, Cai Q, Long J. Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer. Int. J. Cancer [print-electronic]. 2016 Sep 9/15/2016; 139(6): 1303-17. PMID: 27087578, PMCID: PMC5110427, DOI: 10.1002/ijc.30150, ISSN: 1097-0215.

Guo X, Delio M, Haque N, Castellanos R, Hestand MS, Vermeesch JR, Morrow BE, Zheng D. Variant discovery and breakpoint region prediction for studying the human 22q11.2 deletion using BAC clone and whole genome sequencing analysis. Hum. Mol. Genet [print-electronic]. 2016 Sep 9/1/2016; 25(17): 3754-67. PMID: 27436579, PMCID: PMC5216616, PII: ddw221, DOI: 10.1093/hmg/ddw221, ISSN: 1460-2083.

Wang Y, Guo X, Bray MJ, Ding Z, Zhao Z. An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC). BMC Genomics. 2016 Aug 8/22/2016; 17 Suppl 7: 515. PMID: 27556922, PMCID: PMC5001239, PII: 10.1186/s12864-016-2906-9, DOI: 10.1186/s12864-016-2906-9, ISSN: 1471-2164.

Guo X, Cai Q, Bao P, Wu J, Wen W, Ye F, Zheng W, Zheng Y, Shu XO. Long-term soy consumption and tumor tissue MicroRNA and gene expression in triple-negative breast cancer. Cancer [print-electronic]. 2016 Aug 8/15/2016; 122(16): 2544-51. PMID: 27183356, PMCID: PMC4974138, DOI: 10.1002/cncr.29981, ISSN: 1097-0142.

Han MR, Long J, Choi JY, Low SK, Kweon SS, Zheng Y, Cai Q, Shi J, Guo X, Matsuo K, Iwasaki M, Shen CY, Kim MK, Wen W, Li B, Takahashi A, Shin MH, Xiang YB, Ito H, Kasuga Y, Noh DY, Matsuda K, Park MH, Gao YT, Iwata H, Tsugane S, Park SK, Kubo M, Shu XO, Kang D, Zheng W. Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci. Hum. Mol. Genet [print-electronic]. 2016 Aug 8/1/2016; 25(15): 3361-71. PMID: 27354352, PMCID: PMC5179918, PII: ddw164, DOI: 10.1093/hmg/ddw164, ISSN: 1460-2083.

Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL, Milne RL, Bolla MK, Wang Q, Dennis J, Agata S, Ahmed S, Aittomäki K, Andrulis IL, Anton-Culver H, Antonenkova NN, Arason A, Arndt V, Arun BK, Arver B, Bacot F, Barrowdale D, Baynes C, Beeghly-Fadiel A, Benitez J, Bermisheva M, Blomqvist C, Blot WJ, Bogdanova NV, Bojesen SE, Bonanni B, Borresen-Dale AL, Brand JS, Brauch H, Brennan P, Brenner H, Broeks A, Brüning T, Burwinkel B, Buys SS, Cai Q, Caldes T, Campbell I, Carpenter J, Chang-Claude J, Choi JY, Claes KB, Clarke C, Cox A, Cross SS, Czene K, Daly MB, de la Hoya M, De Leeneer K, Devilee P, Diez O, Domchek SM, Doody M, Dorfling CM, Dörk T, Dos-Santos-Silva I, Dumont M, Dwek M, Dworniczak B, Egan K, Eilber U, Einbeigi Z, Ejlertsen B, Ellis S, Frost D, Lalloo F, , Fasching PA, Figueroa J, Flyger H, Friedlander M, Friedman E, Gambino G, Gao YT, Garber J, García-Closas M, Gehrig A, Damiola F, Lesueur F, Mazoyer S, Stoppa-Lyonnet D, , Giles GG, Godwin AK, Goldgar DE, González-Neira A, Greene MH, Guénel P, Haeberle L, Haiman CA, Hallberg E, Hamann U, Hansen TV, Hart S, Hartikainen JM, Hartman M, Hassan N, Healey S, Hogervorst FB, Verhoef S, , Hendricks CB, Hillemanns P, Hollestelle A, Hulick PJ, Hunter DJ, Imyanitov EN, Isaacs C, Ito H, Jakubowska A, Janavicius R, Jaworska-Bieniek K, Jensen UB, John EM, Joly Beauparlant C, Jones M, Kabisch M, Kang D, Karlan BY, Kauppila S, Kerin MJ, Khan S, Khusnutdinova E, Knight JA, Konstantopoulou I, Kraft P, Kwong A, Laitman Y, Lambrechts D, Lazaro C, Le Marchand L, Lee CN, Lee MH, Lester J, Li J, Liljegren A, Lindblom A, Lophatananon A, Lubinski J, Mai PL, Mannermaa A, Manoukian S, Margolin S, Marme F, Matsuo K, McGuffog L, Meindl A, Menegaux F, Montagna M, Muir K, Mulligan AM, Nathanson KL, Neuhausen SL, Nevanlinna H, Newcomb PA, Nord S, Nussbaum RL, Offit K, Olah E, Olopade OI, Olswold C, Osorio A, Papi L, Park-Simon TW, Paulsson-Karlsson Y, Peeters S, Peissel B, Peterlongo P, Peto J, Pfeiler G, Phelan CM, Presneau N, Radice P, Rahman N, Ramus SJ, Rashid MU, Rennert G, Rhiem K, Rudolph A, Salani R, Sangrajrang S, Sawyer EJ, Schmidt MK, Schmutzler RK, Schoemaker MJ, Schürmann P, Seynaeve C, Shen CY, Shrubsole MJ, Shu XO, Sigurdson A, Singer CF, Slager S, Soucy P, Southey M, Steinemann D, Swerdlow A, Szabo CI, Tchatchou S, Teixeira MR, Teo SH, Terry MB, Tessier DC, Teulé A, Thomassen M, Tihomirova L, Tischkowitz M, Toland AE, Tung N, Turnbull C, van den Ouweland AM, van Rensburg EJ, Ven den Berg D, Vijai J, Wang-Gohrke S, Weitzel JN, Whittemore AS, Winqvist R, Wong TY, Wu AH, Yannoukakos D, Yu JC, Pharoah PD, Hall P, Chenevix-Trench G, , , Dunning AM, Simard J, Couch FJ, Antoniou AC, Easton DF, Zheng W. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Res. 2016 Jun 6/21/2016; 18(1): 64. PMID: 27459855, PMCID: PMC4962376, PII: 10.1186/s13058-016-0718-0, DOI: 10.1186/s13058-016-0718-0, ISSN: 1465-542X.

Zeng C, Matsuda K, Jia WH, Chang J, Kweon SS, Xiang YB, Shin A, Jee SH, Kim DH, Zhang B, Cai Q, Guo X, Long J, Wang N, Courtney R, Pan ZZ, Wu C, Takahashi A, Shin MH, Matsuo K, Matsuda F, Gao YT, Oh JH, Kim S, Jung KJ, Ahn YO, Ren Z, Li HL, Wu J, Shi J, Wen W, Yang G, Li B, Ji BT, , Brenner H, Schoen RE, Küry S, , Gruber SB, Schumacher FR, Stenzel SL, , Casey G, Hopper JL, Jenkins MA, Kim HR, Jeong JY, Park JW, Tajima K, Cho SH, Kubo M, Shu XO, Lin D, Zeng YX, Zheng W. Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. Gastroenterology [print-electronic]. 2016 Jun; 150(7): 1633-45. PMID: 26965516, PMCID: PMC4909543, PII: S0016-5085(16)00299-7, DOI: 10.1053/j.gastro.2016.02.076, ISSN: 1528-0012.

Sun Y, Ye C, Guo X, Wen W, Long J, Gao YT, Shu XO, Zheng W, Cai Q. Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1. Carcinogenesis [print-electronic]. 2016 Feb; 37(2): 163-8. PMID: 26645718, PMCID: PMC5006208, PII: bgv170, DOI: 10.1093/carcin/bgv170, ISSN: 1460-2180.

Wen W, Kato N, Hwang JY, Guo X, Tabara Y, Li H, Dorajoo R, Yang X, Tsai FJ, Li S, Wu Y, Wu T, Kim S, Guo X, Liang J, Shungin D, Adair LS, Akiyama K, Allison M, Cai Q, Chang LC, Chen CH, Chen YT, Cho YS, Choi BY, Gao Y, Go MJ, Gu D, Han BG, He M, Hixson JE, Hu Y, Huang T, Isono M, Jung KJ, Kang D, Kim YJ, Kita Y, Lee J, Lee NR, Lee J, Wang Y, Liu JJ, Long J, Moon S, Nakamura Y, Nakatochi M, Ohnaka K, Rao D, Shi J, Sull JW, Tan A, Ueshima H, Wu C, Xiang YB, Yamamoto K, Yao J, Ye X, Yokota M, Zhang X, Zheng Y, Qi L, Rotter JI, Jee SH, Lin D, Mohlke KL, He J, Mo Z, Wu JY, Tai ES, Lin X, Miki T, Kim BJ, Takeuchi F, Zheng W, Shu XO. Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Sci Rep. 2016 Jan 1/20/2016; 6: 17958. PMID: 26785701, PMCID: PMC4726286, PII: srep17958, DOI: 10.1038/srep17958, ISSN: 2045-2322.

Zhang Y, Delahanty R, Guo X, Zheng W, Long J. Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer. Hum. Genomics. 2015 Dec 12/18/2015; 9: 34. PMID: 26682542, PMCID: PMC4684623, PII: 10.1186/s40246-015-0056-9, DOI: 10.1186/s40246-015-0056-9, ISSN: 1479-7364.

Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Milne RL, Shu XO, Cai Q, Beesley J, Kar SP, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Blot W, Bogdanova N, Bojesen SE, Brauch H, Brenner H, Brinton L, Broeks A, Brüning T, Burwinkel B, Cai H, Canisius S, Chang-Claude J, Choi JY, Couch FJ, Cox A, Cross SS, Czene K, Darabi H, Devilee P, Droit A, Dörk T, Fasching PA, Fletcher O, Flyger H, Fostira F, Gaborieau V, García-Closas M, Giles GG, Grip M, Guénel P, Haiman CA, Hamann U, Hartman M, Hollestelle A, Hopper JL, Hsiung CN, Ito H, Jakubowska A, Johnson N, Kabisch M, Kang D, Khan S, Knight JA, Kosma VM, Lambrechts D, Le Marchand L, Li J, Lindblom A, Lophatananon A, Lubinski J, Mannermaa A, Manoukian S, Margolin S, Marme F, Matsuo K, McLean CA, Meindl A, Muir K, Neuhausen SL, Nevanlinna H, Nord S, Olson JE, Orr N, Peterlongo P, Putti TC, Rudolph A, Sangrajrang S, Sawyer EJ, Schmidt MK, Schmutzler RK, Shen CY, Shi J, Shrubsole MJ, Southey MC, Swerdlow A, Teo SH, Thienpont B, Toland AE, Tollenaar RA, Tomlinson IP, Truong T, Tseng CC, van den Ouweland A, Wen W, Winqvist R, Wu A, Yip CH, Zamora MP, Zheng Y, Hall P, Pharoah PD, Simard J, Chenevix-Trench G, , Dunning AM, Easton DF, Zheng W. Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2015 Nov; 24(11): 1680-91. PMID: 26354892, PMCID: PMC4633342, PII: 1055-9965.EPI-15-0363, DOI: 10.1158/1055-9965.EPI-15-0363, ISSN: 1538-7755.

Liu Y, Cai Q, Bao PP, Su Y, Cai H, Wu J, Ye F, Guo X, Zheng W, Zheng Y, Shu XO. Tumor tissue microRNA expression in association with triple-negative breast cancer outcomes. Breast Cancer Res. Treat [print-electronic]. 2015 Jul; 152(1): 183-91. PMID: 26062749, PMCID: PMC4484742, DOI: 10.1007/s10549-015-3460-x, ISSN: 1573-7217.

Guo X, Xu Y, Zhao Z. In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAFV600E in melanoma. Mol. Cancer. 2015 Mar 3/14/2015; 14: 60. PMID: 25890285, PMCID: PMC4373107, PII: 10.1186/s12943-015-0328-y, DOI: 10.1186/s12943-015-0328-y, ISSN: 1476-4598.

Caescu CI, Guo X, Tesfa L, Bhagat TD, Verma A, Zheng D, Stanley ER. Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21. Blood [print-electronic]. 2015 Feb 2/19/2015; 125(8): e1-13. PMID: 25573988, PMCID: PMC4335087, PII: blood-2014-10-608000, DOI: 10.1182/blood-2014-10-608000, ISSN: 1528-0020.

Xu Y, Guo X, Sun J, Zhao Z. Snowball: resampling combined with distance-based regression to discover transcriptional consequences of a driver mutation. Bioinformatics [print-electronic]. 2015 Jan 1/1/2015; 31(1): 84-93. PMID: 25192743, PMCID: PMC4271146, PII: btu603, DOI: 10.1093/bioinformatics/btu603, ISSN: 1367-4811.

Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Hum. Mol. Genet [print-electronic]. 2014 Oct 10/15/2014; 23(20): 5492-504. PMID: 24861553, PMCID: PMC4168820, PII: ddu248, DOI: 10.1093/hmg/ddu248, ISSN: 1460-2083.

Guo X, Lin M, Rockowitz S, Lachman HM, Zheng D. Characterization of human pseudogene-derived non-coding RNAs for functional potential. PLoS ONE. 2014; 9(4): e93972. PMID: 24699680, PMCID: PMC3974860, PII: PONE-D-14-03187, DOI: 10.1371/journal.pone.0093972, ISSN: 1932-6203.

Keyes BE, Segal JP, Heller E, Lien WH, Chang CY, Guo X, Oristian DS, Zheng D, Fuchs E. Nfatc1 orchestrates aging in hair follicle stem cells. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2013 Dec 12/17/2013; 110(51): E4950-9. PMID: 24282298, PMCID: PMC3870727, PII: 1320301110, DOI: 10.1073/pnas.1320301110, ISSN: 1091-6490.

Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E. Architectural niche organization by LHX2 is linked to hair follicle stem cell function. Cell Stem Cell. 2013 Sep 9/5/2013; 13(3): 314-27. PMID: 24012369, PMCID: PMC3856689, PII: S1934-5909(13)00306-8, DOI: 10.1016/j.stem.2013.06.018, ISSN: 1875-9777.

Wontakal SN, Guo X, Smith C, MacCarthy T, Bresnick EH, Bergman A, Snyder MP, Weissman SM, Zheng D, Skoultchi AI. A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2012 Mar 3/6/2012; 109(10): 3832-7. PMID: 22357756, PMCID: PMC3309740, PII: 1121019109, DOI: 10.1073/pnas.1121019109, ISSN: 1091-6490.

Pedrosa E, Sandler V, Shah A, Carroll R, Chang C, Rockowitz S, Guo X, Zheng D, Lachman HM. Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells. J. Neurogenet [print-electronic]. 2011 Oct; 25(3): 88-103. PMID: 21797804, DOI: 10.3109/01677063.2011.597908, ISSN: 1563-5260.

Lien WH, Guo X, Polak L, Lawton LN, Young RA, Zheng D, Fuchs E. Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell. 2011 Sep 9/2/2011; 9(3): 219-32. PMID: 21885018, PMCID: PMC3166618, PII: S1934-5909(11)00378-X, DOI: 10.1016/j.stem.2011.07.015, ISSN: 1875-9777.

Wontakal SN, Guo X, Will B, Shi M, Raha D, Mahajan MC, Weissman S, Snyder M, Steidl U, Zheng D, Skoultchi AI. A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1. PLoS Genet [print-electronic]. 2011 Jun; 7(6): e1001392. PMID: 21695229, PMCID: PMC3111485, PII: 10-PLGE-RA-3770R3, DOI: 10.1371/journal.pgen.1001392, ISSN: 1553-7404.

Guo X, Freyer L, Morrow B, Zheng D. Characterization of the past and current duplication activities in the human 22q11.2 region. BMC Genomics. 2011 Jan 1/26/2011; 12: 71. PMID: 21269513, PMCID: PMC3040729, PII: 1471-2164-12-71, DOI: 10.1186/1471-2164-12-71, ISSN: 1471-2164.

Pedrosa E, Shah A, Tenore C, Capogna M, Villa C, Guo X, Zheng D, Lachman HM. ß-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network. J. Neurogenet [print-electronic]. 2010 Dec; 24(4): 182-93. PMID: 20615089, DOI: 10.3109/01677063.2010.495182, ISSN: 1563-5260.

Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL. ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature [print-electronic]. 2010 Oct 10/14/2010; 467(7317): 849-53. PMID: 20927104, PMCID: PMC2955195, PII: nature09409, DOI: 10.1038/nature09409, ISSN: 1476-4687.

Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons RJ, Higgs DR, Cristea IM, Urnov FD, Zheng D, Allis CD. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell. 2010 Mar 3/5/2010; 140(5): 678-91. PMID: 20211137, PMCID: PMC2885838, PII: S0092-8674(10)00004-8, DOI: 10.1016/j.cell.2010.01.003, ISSN: 1097-4172.

Guo X, Zhang Z, Gerstein MB, Zheng D. Small RNAs originated from pseudogenes: cis- or trans-acting?. PLoS Comput. Biol [print-electronic]. 2009 Jul; 5(7): e1000449. PMID: 19649160, PMCID: PMC2708354, DOI: 10.1371/journal.pcbi.1000449, ISSN: 1553-7358.

Wu B, Melcher U, Guo X, Wang X, Fan L, Zhou G. Assessment of codivergence of mastreviruses with their plant hosts. BMC Evol. Biol. 2008 Dec 12/18/2008; 8: 335. PMID: 19094195, PMCID: PMC2630985, PII: 1471-2148-8-335, DOI: 10.1186/1471-2148-8-335, ISSN: 1471-2148.

Guo X, Gui Y, Wang Y, Zhu QH, Helliwell C, Fan L. Selection and mutation on microRNA target sequences during rice evolution. BMC Genomics. 2008 Oct 10/2/2008; 9: 454. PMID: 18831738, PMCID: PMC2567346, PII: 1471-2164-9-454, DOI: 10.1186/1471-2164-9-454, ISSN: 1471-2164.

Guo X, Ruan S, Hu W, Cai D, Fan L. Chloroplast DNA insertions into the nuclear genome of rice: the genes, sites and ages of insertion involved. Funct. Integr. Genomics [print-electronic]. 2008 May; 8(2): 101-8. PMID: 17994302, DOI: 10.1007/s10142-007-0067-2, ISSN: 1438-793X.

Guo X, Wang Y, Keightley PD, Fan L. Patterns of selective constraints in noncoding DNA of rice. BMC Evol. Biol. 2007 Nov 11/1/2007; 7: 208. PMID: 17976238, PMCID: PMC2174951, PII: 1471-2148-7-208, DOI: 10.1186/1471-2148-7-208, ISSN: 1471-2148.

Wang S, Zhu QH, Guo X, Gui Y, Bao J, Helliwell C, Fan L. Molecular evolution and selection of a gene encoding two tandem microRNAs in rice. FEBS Lett [print-electronic]. 2007 Oct 10/2/2007; 581(24): 4789-93. PMID: 17884044, PII: S0014-5793(07)00967-2, DOI: 10.1016/j.febslet.2007.09.002, ISSN: 0014-5793.

Guo X, Bao J, Fan L. Evidence of selectively driven codon usage in rice: implications for GC content evolution of Gramineae genes. FEBS Lett [print-electronic]. 2007 Mar 3/6/2007; 581(5): 1015-21. PMID: 17306258, PII: S0014-5793(07)00138-X, DOI: 10.1016/j.febslet.2007.01.088, ISSN: 0014-5793.