Thomas J. Wang, M.D.

Faculty Appointments
Director, Division of Cardiovascular Medicine Professor of Medicine Gottlieb C. Friesinger II Chair in Cardiovascular Medicine
M.D., Harvard Medical School, Boston, MassachusettsB.S., Harvard University, Cambridge, Massachusetts
Gupta DK, Wang TJ. Looking for a Brighter Future in Heart Failure: A Role for Vitamin D Supplementation? [editorial]. J. Am. Coll. Cardiol. 2016 Jun 6/7/2016; 67(22): 2604-6. PMID: 27256831, PII: S0735-1097(16)32700-0, DOI: 10.1016/j.jacc.2016.04.012, ISSN: 1558-3597.

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction" [letter]. Circulation. 2016 Jun 6/7/2016; 133(23): e692-3. PMID: 27267541, PMCID: PMC4902166, PII: CIRCULATIONAHA.116.022835, DOI: 10.1161/CIRCULATIONAHA.116.022835, ISSN: 1524-4539.

Wu C, Arora P, Agha O, Hurst LA, Allen K, Nathan DI, Hu D, Jiramongkolchai P, Smith JG, Melander O, Trenson S, Janssens SP, Domian I, Wang TJ, Bloch KD, Buys ES, Bloch DB, Newton-Cheh C. Novel microRNA regulators of atrial natriuretic peptide production. Mol. Cell. Biol [print-electronic]. 2016 May 5/16/2016; PMID: 27185878, PII: MCB.01114-15, DOI: 10.1128/MCB.01114-15, ISSN: 1098-5549.

Ward MJ, Kripalani S, Zhu Y, Storrow AB, Wang TJ, Speroff T, Munoz D, Dittus RS, Harrell FE, Self WH. Role of Health Insurance Status in Interfacility Transfers of Patients With ST-Elevation Myocardial Infarction. Am. J. Cardiol [print-electronic]. 2016 May 5/14/2016; PMID: 27282834, PII: S0002-9149(16)30861-X, DOI: 10.1016/j.amjcard.2016.05.007, ISSN: 1879-1913.

Munro HM, Tarone RE, Wang TJ, Blot WJ. Menthol and Nonmenthol Cigarette Smoking: All-Cause Deaths, Cardiovascular Disease Deaths, and Other Causes of Death Among Blacks and Whites. Circulation [print-electronic]. 2016 May 5/10/2016; 133(19): 1861-6. PMID: 27022064, PMCID: PMC4886344, PII: CIRCULATIONAHA.115.020536, DOI: 10.1161/CIRCULATIONAHA.115.020536, ISSN: 1524-4539.

Walford GA, Ma Y, Clish C, Florez JC, Wang TJ, Gerszten RE, . Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program. Diabetes [print-electronic]. 2016 May; 65(5): 1424-33. PMID: 26861782, PMCID: PMC4839205, PII: db15-1063, DOI: 10.2337/db15-1063, ISSN: 1939-327X.

Andersson C, Enserro D, Sullivan L, Wang TJ, Januzzi JL, Benjamin EJ, Vita JA, Hamburg NM, Larson MG, Mitchell GF, Vasan RS. Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis [print-electronic]. 2016 May; 248: 245-51. PMID: 26972631, PII: S0021-9150(16)30056-9, DOI: 10.1016/j.atherosclerosis.2016.02.013, ISSN: 1879-1484.

Ferguson JF, Wang TJ. Branched-Chain Amino Acids and Cardiovascular Disease: Does Diet Matter? [editorial]. Clin. Chem [print-electronic]. 2016 Apr; 62(4): 545-7. PMID: 26883074, PII: clinchem.2016.254318, DOI: 10.1373/clinchem.2016.254318, ISSN: 1530-8561.

Santhanakrishnan R, Wang N, Larson MG, Magnani JM, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 Mar; 4(3): e002956. PMID: 27016575, PII: JAHA.115.002956, DOI: 10.1161/JAHA.115.002956, ISSN: 2047-9980.

Arora P, Wu C, Hamid T, Arora G, Agha O, Allen K, Tainsh RE, Hu D, Ryan RA, Domian IJ, Buys ES, Bloch DB, Prabhu SD, Bloch KD, Newton-Cheh C, Wang TJ. Acute Metabolic Influences on the Natriuretic Peptide System in Humans. J. Am. Coll. Cardiol. 2016 Feb 2/23/2016; 67(7): 804-12. PMID: 26892417, PII: S0735-1097(15)07792-X, DOI: 10.1016/j.jacc.2015.11.049, ISSN: 1558-3597.

Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, DeCarli C, Vasan RS, Wang TJ, Himali JJ, Annweiler C, Seshadri S. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. J. Alzheimers Dis. 2016 Feb 2/6/2016; 51(2): 451-61. PMID: 26890771, PII: JAD150991, DOI: 10.3233/JAD-150991, ISSN: 1875-8908.

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation [print-electronic]. 2016 Feb 2/2/2016; 133(5): 484-92. PMID: 26746177, PMCID: PMC4738087, PII: CIRCULATIONAHA.115.018614, DOI: 10.1161/CIRCULATIONAHA.115.018614, ISSN: 1524-4539.

Konijeti GG, Arora P, Boylan MR, Song Y, Huang S, Harrell F, Newton-Cheh C, O'Neill D, Korzenik J, Wang TJ, Chan AT. Vitamin D Supplementation Modulates T Cell-Mediated Immunity in Humans: Results from a Randomized Control Trial. J. Clin. Endocrinol. Metab [print-electronic]. 2016 Feb; 101(2): 533-8. PMID: 26653112, PMCID: PMC4880125, DOI: 10.1210/jc.2015-3599, ISSN: 1945-7197.

Zhang H, Thoonen R, Yao V, Buys ES, Popovich J, Su YR, Wang TJ, Scherrer-Crosbie M. Regulation of B-type natriuretic peptide synthesis by insulin in obesity in male mice. Exp. Physiol [print-electronic]. 2016 Jan; 101(1): 113-23. PMID: 26446173, DOI: 10.1113/EP085091, ISSN: 1469-445X.

Wang TJ. Vitamin D and Cardiovascular Disease. Annu. Rev. Med. 2016; 67: 261-72. PMID: 26768241, DOI: 10.1146/annurev-med-051214-025146, ISSN: 1545-326X.

Ho JE, Larson MG, Ghorbani A, Cheng S, Chen MH, Keyes M, Rhee EP, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes. PLoS ONE. 2016; 11(2): e0148361. PMID: 26863521, PMCID: PMC4749349, PII: PONE-D-15-48168, DOI: 10.1371/journal.pone.0148361, ISSN: 1932-6203.

Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL, Vasan RS, Seshadri S. Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke. Stroke [print-electronic]. 2015 Sep; 46(9): 2568-75. PMID: 26219649, PMCID: PMC4550531, PII: STROKEAHA.115.009026, DOI: 10.1161/STROKEAHA.115.009026, ISSN: 1524-4628.

Magnusson M, Wang TJ, Clish C, Engström G, Nilsson P, Gerszten RE, Melander O. Dimethylglycine Deficiency and the Development of Diabetes. Diabetes [print-electronic]. 2015 Aug; 64(8): 3010-6. PMID: 25795213, PMCID: PMC4512219, PII: db14-1863, DOI: 10.2337/db14-1863, ISSN: 1939-327X.

Gupta DK, de Lemos JA, Ayers CR, Berry JD, Wang TJ. Racial Differences in Natriuretic Peptide Levels: The Dallas Heart Study. JACC Heart Fail [print-electronic]. 2015 Jul; 3(7): 513-9. PMID: 26071618, PMCID: PMC4498971, PII: S2213-1779(15)00213-9, DOI: 10.1016/j.jchf.2015.02.008, ISSN: 2213-1787.

Wang TJ, Wells QS. Vitamin D Deficiency and Heart Failure Risk: Not so Black and White? [editorial]. JACC Heart Fail [print-electronic]. 2015 May; 3(5): 357-9. PMID: 25863974, PII: S2213-1779(15)00090-6, DOI: 10.1016/j.jchf.2015.02.005, ISSN: 2213-1787.

Wang TJ, Gupta DK. Metabolite profiles in heart failure: looking for unique signatures in a heterogeneous syndrome [editorial]. J. Am. Coll. Cardiol. 2015 Apr 4/21/2015; 65(15): 1521-4. PMID: 25881933, PII: S0735-1097(15)00606-3, DOI: 10.1016/j.jacc.2015.02.019, ISSN: 1558-3597.

Ho JE, Sritara P, deFilippi CR, Wang TJ. Soluble ST2 testing in the general population. Am. J. Cardiol [print-electronic]. 2015 Apr 4/2/2015; 115(7 Suppl): 22B-5B. PMID: 25665763, PII: S0002-9149(15)00119-8, DOI: 10.1016/j.amjcard.2015.01.036, ISSN: 1879-1913.

Gupta DK, Wang TJ. Biomarker discovery: searching for quality in quantity [editorial]. Circ Cardiovasc Genet. 2015 Feb; 8(1): 8-10. PMID: 25691685, PII: CIRCGENETICS.115.000973, DOI: 10.1161/CIRCGENETICS.115.000973, ISSN: 1942-3268.

Arora P, Song Y, Dusek J, Plotnikoff G, Sabatine MS, Cheng S, Valcour A, Swales H, Taylor B, Carney E, Guanaga D, Young JR, Karol C, Torre M, Azzahir A, Strachan SM, O'Neill DC, Wolf M, Harrell F, Newton-Cheh C, Wang TJ. Vitamin D therapy in individuals with prehypertension or hypertension: the DAYLIGHT trial. Circulation [print-electronic]. 2015 Jan 1/20/2015; 131(3): 254-62. PMID: 25359163, PII: CIRCULATIONAHA.114.011732, DOI: 10.1161/CIRCULATIONAHA.114.011732, ISSN: 1524-4539.

Gupta DK, Wang TJ. Natriuretic Peptides and Cardiometabolic Health. Circ. J [print-electronic]. 2015; 79(8): 1647-55. PMID: 26103984, PMCID: PMC4893202, DOI: 10.1253/circj.CJ-15-0589, ISSN: 1347-4820.

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6: 6791. PMID: 25864806, PMCID: PMC4396657, PII: ncomms7791, DOI: 10.1038/ncomms7791, ISSN: 2041-1723.

Arora P, Reingold J, Baggish A, Guanaga DP, Wu C, Ghorbani A, Song Y, Chen-Tournaux A, Khan AM, Tainsh LT, Buys ES, Williams JS, Heublein DM, Burnett JC, Semigran MJ, Bloch KD, Scherrer-Crosbie M, Newton-Cheh C, Kaplan LM, Wang TJ. Weight loss, saline loading, and the natriuretic peptide system. J Am Heart Assoc. 2015 Jan; 4(1): e001265. PMID: 25595796, PMCID: PMC4330054, PII: jah3794, DOI: 10.1161/JAHA.114.001265, ISSN: 2047-9980.

Wang TJ. The obesity paradox in heart failure: weighing the evidence [editorial]. J. Am. Coll. Cardiol. 2014 Dec 12/30/2014; 64(25): 2750-2. PMID: 25541127, PII: S0735-1097(14)06687-X, DOI: 10.1016/j.jacc.2014.09.068, ISSN: 1558-3597.

Dashti HS, Shea MK, Smith CE, Tanaka T, Hruby A, Richardson K, Wang TJ, Nalls MA, Guo X, Liu Y, Yao J, Li D, Johnson WC, Benjamin EJ, Kritchevsky SB, Siscovick DS, Ordovás JM, Booth SL. Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. Am. J. Clin. Nutr [print-electronic]. 2014 Dec; 100(6): 1462-9. PMID: 25411281, PMCID: PMC4232014, PII: ajcn.114.093146, DOI: 10.3945/ajcn.114.093146, ISSN: 1938-3207.

Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur. Heart J [print-electronic]. 2014 Nov 11/7/2014; 35(42): 2972-9. PMID: 24742886, PMCID: PMC4223610, PII: ehu153, DOI: 10.1093/eurheartj/ehu153, ISSN: 1522-9645.

Xanthakis V, Enserro DM, Murabito JM, Polak JF, Wollert KC, Januzzi JL, Wang TJ, Tofler G, Vasan RS. Ideal cardiovascular health: associations with biomarkers and subclinical disease and impact on incidence of cardiovascular disease in the Framingham Offspring Study. Circulation [print-electronic]. 2014 Nov 11/4/2014; 130(19): 1676-83. PMID: 25274000, PII: CIRCULATIONAHA.114.009273, DOI: 10.1161/CIRCULATIONAHA.114.009273, ISSN: 1524-4539.

Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community. Clin. Chem [print-electronic]. 2014 Nov; 60(11): 1402-8. PMID: 25237063, PMCID: PMC4376479, PII: clinchem.2014.227116, DOI: 10.1373/clinchem.2014.227116, ISSN: 1530-8561.

Mayers JR, Wu C, Clish CB, Kraft P, Torrence ME, Fiske BP, Yuan C, Bao Y, Townsend MK, Tworoger SS, Davidson SM, Papagiannakopoulos T, Yang A, Dayton TL, Ogino S, Stampfer MJ, Giovannucci EL, Qian ZR, Rubinson DA, Ma J, Sesso HD, Gaziano JM, Cochrane BB, Liu S, Wactawski-Wende J, Manson JE, Pollak MN, Kimmelman AC, Souza A, Pierce K, Wang TJ, Gerszten RE, Fuchs CS, Vander Heiden MG, Wolpin BM. Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development. Nat. Med [print-electronic]. 2014 Oct; 20(10): 1193-8. PMID: 25261994, PMCID: PMC4191991, PII: nm.3686, DOI: 10.1038/nm.3686, ISSN: 1546-170X.

Ho JE, Arora P, Walford GA, Ghorbani A, Guanaga DP, Dhakal BP, Nathan DI, Buys ES, Florez JC, Newton-Cheh C, Lewis GD, Wang TJ. Effect of phosphodiesterase inhibition on insulin resistance in obese individuals. J Am Heart Assoc. 2014 Oct; 3(5): e001001. PMID: 25213566, PMCID: PMC4323801, PII: jah3640, DOI: 10.1161/JAHA.114.001001, ISSN: 2047-9980.

Luther JM, Byrne LM, Yu C, Wang TJ, Brown NJ. Dietary sodium restriction decreases insulin secretion without affecting insulin sensitivity in humans. J. Clin. Endocrinol. Metab [print-electronic]. 2014 Oct; 99(10): E1895-902. PMID: 25029426, PMCID: PMC4184066, DOI: 10.1210/jc.2014-2122, ISSN: 1945-7197.

Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2014 Sep; 34(9): 2100-5. PMID: 25060794, PMCID: PMC4142677, PII: ATVBAHA.114.303579, DOI: 10.1161/ATVBAHA.114.303579, ISSN: 1524-4636.

Vimaleswaran KS, Cavadino A, Berry DJ, , Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D, Zgaga L, Thiering E, Vitart V, Fraser RM, Huffman JE, de Boer RA, Schöttker B, Saum KU, McCarthy MI, Dupuis J, Herzig KH, Sebert S, Pouta A, Laitinen J, Kleber ME, Navis G, Lorentzon M, Jameson K, Arden N, Cooper JA, Acharya J, Hardy R, Raitakari O, Ripatti S, Billings LK, Lahti J, Osmond C, Penninx BW, Rejnmark L, Lohman KK, Paternoster L, Stolk RP, Hernandez DG, Byberg L, Hagström E, Melhus H, Ingelsson E, Mellström D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Tiesler CM, Jula A, Navarro P, Wright AF, Polasek O, , , , , Wilson JF, Rudan I, Salomaa V, Heinrich J, Campbell H, Price JF, Karlsson M, Lind L, Michaëlsson K, Bandinelli S, Frayling TM, Hartman CA, Sørensen TI, Kritchevsky SB, Langdahl BL, Eriksson JG, Florez JC, Spector TD, Lehtimäki T, Kuh D, Humphries SE, Cooper C, Ohlsson C, März W, de Borst MH, Kumari M, Kivimaki M, Wang TJ, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Hingorani AD, Pilz S, Whittaker JC, Järvelin MR, Hyppönen E. Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. Lancet Diabetes Endocrinol [print-electronic]. 2014 Sep; 2(9): 719-29. PMID: 24974252, PMCID: PMC4582411, PII: S2213-8587(14)70113-5, DOI: 10.1016/S2213-8587(14)70113-5, ISSN: 2213-8595.

Walford GA, Porneala BC, Dauriz M, Vassy JL, Cheng S, Rhee EP, Wang TJ, Meigs JB, Gerszten RE, Florez JC. Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes. Diabetes Care [print-electronic]. 2014 Sep; 37(9): 2508-14. PMID: 24947790, PMCID: PMC4140156, PII: dc14-0560, DOI: 10.2337/dc14-0560, ISSN: 1935-5548.

Patel DK, Green KD, Fudim M, Harrell FE, Wang TJ, Robbins MA. Racial differences in the prevalence of severe aortic stenosis. J Am Heart Assoc. 2014 Jun; 3(3): e000879. PMID: 24870936, PMCID: PMC4309086, PII: jah3540, DOI: 10.1161/JAHA.114.000879, ISSN: 2047-9980.

Mahmood SS, Levy D, Vasan RS, Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet [print-electronic]. 2014 Mar 3/15/2014; 383(9921): 999-1008. PMID: 24084292, PMCID: PMC4159698, PII: S0140-6736(13)61752-3, DOI: 10.1016/S0140-6736(13)61752-3, ISSN: 1474-547X.

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 1/7/2014; 19(1): 96-108. PMID: 24411942, PMCID: PMC4017355, PII: S1550-4131(13)00497-X, DOI: 10.1016/j.cmet.2013.12.003, ISSN: 1932-7420.

Velagaleti RS, Gona P, Pencina MJ, Aragam J, Wang TJ, Levy D, D'Agostino RB, Lee DS, Kannel WB, Benjamin EJ, Vasan RS. Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction. Am. J. Cardiol [print-electronic]. 2014 Jan 1/1/2014; 113(1): 117-22. PMID: 24210333, PMCID: PMC3881171, PII: S0002-9149(13)01954-1, DOI: 10.1016/j.amjcard.2013.09.028, ISSN: 1879-1913.

Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am. Heart J [print-electronic]. 2014 Jan; 167(1): 109-115.e2. PMID: 24332149, PMCID: PMC3884900, PII: S0002-8703(13)00672-8, DOI: 10.1016/j.ahj.2013.10.003, ISSN: 1097-6744.

Soslow JH, Kavanaugh-McHugh A, Wang L, Saurers DL, Kaushik N, Killen SA, Parra DA. A clinical prediction model to estimate the risk for coarctation of the aorta in the presence of a patent ductus arteriosus. J Am Soc Echocardiogr [print-electronic]. 2013 Dec; 26(12): 1379-87. PMID: 24070640, PMCID: PMC3915292, PII: S0894-7317(13)00658-5, DOI: 10.1016/j.echo.2013.08.016, ISSN: 1097-6795.

Walford GA, Davis J, Warner AS, Ackerman RJ, Billings LK, Chamarthi B, Fanelli RR, Hernandez AM, Huang C, Khan SQ, Littleton KR, Lo J, McCarthy RM, Rhee EP, Deik A, Stolerman E, Taylor A, Hudson MS, Wang TJ, Altshuler D, Grant RW, Clish CB, Gerszten RE, Florez JC. Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus. Metab. Clin. Exp [print-electronic]. 2013 Dec; 62(12): 1772-8. PMID: 23953891, PMCID: PMC3833885, PII: S0026-0495(13)00220-5, DOI: 10.1016/j.metabol.2013.07.003, ISSN: 1532-8600.

Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS. Biomarkers of cardiovascular stress and incident chronic kidney disease. Clin. Chem [print-electronic]. 2013 Nov; 59(11): 1613-20. PMID: 23873716, PMCID: PMC3972213, PII: clinchem.2013.205716, DOI: 10.1373/clinchem.2013.205716, ISSN: 1530-8561.

Mak GS, Sawaya H, Khan AM, Arora P, Martinez A, Ryan A, Ernande L, Newton-Cheh C, Wang TJ, Scherrer-Crosbie M. Effects of subacute dietary salt intake and acute volume expansion on diastolic function in young normotensive individuals. Eur Heart J Cardiovasc Imaging [print-electronic]. 2013 Nov; 14(11): 1092-8. PMID: 23515219, PMCID: PMC3806580, PII: jet036, DOI: 10.1093/ehjci/jet036, ISSN: 2047-2412.

Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. 2-Aminoadipic acid is a biomarker for diabetes risk. J. Clin. Invest [print-electronic]. 2013 Oct; 123(10): 4309-17. PMID: 24091325, PMCID: PMC3784523, PII: 64801, DOI: 10.1172/JCI64801, ISSN: 1558-8238.

Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, , , Dehghan A, Lu C, Levy D, Newton-Cheh C, , Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J. Clin. Invest [print-electronic]. 2013 Oct; 123(10): 4208-18. PMID: 23999434, PMCID: PMC3784527, PII: 67119, DOI: 10.1172/JCI67119, ISSN: 1558-8238.

Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ. Atrial natriuretic peptide is negatively regulated by microRNA-425. J. Clin. Invest [print-electronic]. 2013 Aug; 123(8): 3378-82. PMID: 23867623, PMCID: PMC3726159, PII: 67383, DOI: 10.1172/JCI67383, ISSN: 1558-8238.

Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D, Pencina MJ, Fontes JD, Magnani JW, McManus DD, Lubitz SA, Tadros TM, Wang TJ, Ellinor PT, Vasan RS, Benjamin EJ. Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur. J. Heart Fail [print-electronic]. 2013 Aug; 15(8): 843-9. PMID: 23594831, PMCID: PMC3858114, PII: hft041, DOI: 10.1093/eurjhf/hft041, ISSN: 1879-0844.

Ho JE, Larson MG, Vasan RS, Ghorbani A, Cheng S, Rhee EP, Florez JC, Clish CB, Gerszten RE, Wang TJ. Metabolite profiles during oral glucose challenge. Diabetes [print-electronic]. 2013 Aug; 62(8): 2689-98. PMID: 23382451, PMCID: PMC3717862, PII: db12-0754, DOI: 10.2337/db12-0754, ISSN: 1939-327X.

Weiner RB, Wang F, Isaacs SK, Malhotra R, Berkstresser B, Kim JH, Hutter AM, Picard MH, Wang TJ, Baggish AL. Blood pressure and left ventricular hypertrophy during American-style football participation. Circulation. 2013 Jul 7/30/2013; 128(5): 524-31. PMID: 23897848, PII: 128/5/524, DOI: 10.1161/CIRCULATIONAHA.113.003522, ISSN: 1524-4539.

Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 7/2/2013; 18(1): 130-43. PMID: 23823483, PMCID: PMC3973158, PII: S1550-4131(13)00257-X, DOI: 10.1016/j.cmet.2013.06.013, ISSN: 1932-7420.

Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS. Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis [print-electronic]. 2013 Jul; 229(1): 228-33. PMID: 23701996, PMCID: PMC3984590, PII: S0021-9150(13)00257-8, DOI: 10.1016/j.atherosclerosis.2013.04.017, ISSN: 1879-1484.

Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. A combined epidemiologic and metabolomic approach improves CKD prediction. J. Am. Soc. Nephrol [print-electronic]. 2013 Jul; 24(8): 1330-8. PMID: 23687356, PMCID: PMC3736702, PII: ASN.2012101006, DOI: 10.1681/ASN.2012101006, ISSN: 1533-3450.

Schnabel RB, Yin X, Larson MG, Yamamoto JF, Fontes JD, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Murabito JM, Vasan RS, Benjamin EJ. Multiple inflammatory biomarkers in relation to cardiovascular events and mortality in the community. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2013 Jul; 33(7): 1728-33. PMID: 23640499, PMCID: PMC3753537, PII: ATVBAHA.112.301174, DOI: 10.1161/ATVBAHA.112.301174, ISSN: 1524-4636.

Ho JE, Larson MG, Ghorbani A, Cheng S, Vasan RS, Wang TJ, Januzzi JL. Soluble ST2 predicts elevated SBP in the community. J. Hypertens. 2013 Jul; 31(7): 1431-6; discussion 1436. PMID: 23615326, PMCID: PMC3986262, DOI: 10.1097/HJH.0b013e3283611bdf, ISSN: 1473-5598.

Ganda A, Magnusson M, Yvan-Charvet L, Hedblad B, Engström G, Ai D, Wang TJ, Gerszten RE, Melander O, Tall AR. Mild renal dysfunction and metabolites tied to low HDL cholesterol are associated with monocytosis and atherosclerosis. Circulation [print-electronic]. 2013 Mar 3/5/2013; 127(9): 988-96. PMID: 23378299, PMCID: PMC4074592, PII: CIRCULATIONAHA.112.000682, DOI: 10.1161/CIRCULATIONAHA.112.000682, ISSN: 1524-4539.

Mahmood SS, Wang TJ. The epidemiology of congestive heart failure: the Framingham Heart Study perspective. Glob Heart. 2013 Mar 3/1/2013; 8(1): 77-82. PMID: 23998000, PMCID: PMC3756692, DOI: 10.1016/j.gheart.2012.12.006, ISSN: 2211-8179.

Xanthakis V, Larson MG, Wollert KC, Aragam J, Cheng S, Ho J, Coglianese E, Levy D, Colucci WS, Michael Felker G, Benjamin EJ, Januzzi JL, Wang TJ, Vasan RS. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. J Am Heart Assoc. 2013; 2(6): e000399. PMID: 24200688, PMCID: PMC3886765, PII: jah3364, DOI: 10.1161/JAHA.113.000399, ISSN: 2047-9980.

Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL, , Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med [print-electronic]. 2013; 10(2): e1001383. PMID: 23393431, PMCID: PMC3564800, PII: PMEDICINE-D-12-01552, DOI: 10.1371/journal.pmed.1001383, ISSN: 1549-1676.

Thomas JC, Oottamasathien S, Makari JH, Honea L, Sharif-Afshar AR, Wang Y, Adams C, Wills ML, Bhowmick NA, Adams MC, Brock JW, Hayward SW, Matusik RJ, Pope JC. Temporal-spatial protein expression in bladder tissue derived from embryonic stem cells. J. Urol [print-electronic]. 2008 Oct; 180(4 Suppl): 1784-9. PMID: 18721943, PII: S0022-5347(08)00693-9, DOI: 10.1016/j.juro.2008.03.098, ISSN: 1527-3792.

Stein S, Thomas EK, Herzog B, Westfall MD, Rocheleau JV, Jackson RS, Wang M, Liang P. NDRG1 is necessary for p53-dependent apoptosis. J. Biol. Chem [print-electronic]. 2004 Nov 11/19/2004; 279(47): 48930-40. PMID: 15377670, PII: M400386200, DOI: 10.1074/jbc.M400386200, ISSN: 0021-9258.