Elizabeth J. Phillips, M.D.

Professor

elizabeth.j.phillips@vanderbilt.edu
Faculty Appointments
Professor of Medicine John A. Oates Chair in Clinical ResearchProfessor of Pathology, Microbiology and ImmunologyProfessor of Pharmacology
Education
M.D., University of Alberta, Alberta, CanadaB.Sc., University of Alberta, Alberta, Canada
Research Description
The Phillips lab has a research and clinical program in drug Hypersensitivity that specifically focuses on the tissue specificity, genetic basis and immunopathogenesis of severe T-cell mediated adverse drug reactions such as Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and drug reaction with eosiniophiia and systemic symptoms. Her lab studies the development of genetic, molecular and cellular signals to predict and prevent these severe life-threatening adverse drug reactions using novel single cell technologies and mass cytometry . Her impact has been national and international and she has forged collaborations with groups in Australia, Africa and Southeast Asia to guide in the implementation of scientific programs to study the expansive and genetically diverse drug hypersensitivity syndromes. This research program is paired with an outpatient clinical drug allergy service which occurs weekly at VASAP (2611 West End Ave).
Clinical Description
Dr. Phillips is a specialist in Infectious Diseases, Clinical Pharmacology, Drug Safety and immunologically mediated adverse drug reactions and has over 25 years of expertise in this area. She runs a specialized drug hypersensitivity clinic that assesses patients with suspected immunologically mediated adverse drug reactions and occurs once weekly at the VASAP site (2611 West End). The clinic provides specialized testing, management and advice to patients and their families including drug skin and patch testing, desensitization and genetic testing.
Research Keywords
HLA, T-cell immunology, immunogenomics, single cell, pharmacogenomics, drug hypersensitivity, SJS/TEN, Adverse drug reactions
Clinical Research Keywords
Drug allergy, hypersensitivity, SJS/TEN, DRESS, de-labeling, skin testing, ELISpot, flow cytometry, pharmacogenomics, pharmacogenetics, HLA, PheWAS, whole genome.
Publications
Coleman DT, Stone CA, Wei WQ, Phillips EJ. Penicillin allergy labels drive perioperative prophylactic antibiotic selection in orthopedic procedures. J Allergy Clin Immunol Pract [print-electronic]. 2020 Jul 7/18/2020; PMID: 32693215, PII: S2213-2198(20)30712-1, DOI: 10.1016/j.jaip.2020.07.007, ISSN: 2213-2201.

Trubiano JA, Gordon CL, Castellucci C, Christo SN, Park SL, Mouhtouris E, Konvinse K, Rose M, Goh M, Boyd AS, Phillips EJ, Mackay LK. Analysis of Skin-Resident Memory T Cells Following Drug Hypersensitivity Reactions. J. Invest. Dermatol [print-electronic]. 2020 Jul; 140(7): 1442-1445.e4. PMID: 31883960, PMCID: PMC7369252, PII: S0022-202X(19)33566-3, DOI: 10.1016/j.jid.2019.11.020, ISSN: 1523-1747.

Mangan BL, McAlister RK, Balko JM, Johnson DB, Moslehi JJ, Gibson A, Phillips EJ. Evolving Insights into the Mechanisms of Toxicity Associated with Immune Checkpoint Inhibitor Therapy. Br J Clin Pharmacol [print-electronic]. 2020 Jun 6/16/2020; PMID: 32543711, DOI: 10.1111/bcp.14433, ISSN: 1365-2125.

Stone CA, Stollings JL, Lindsell CJ, Dear ML, Buie RB, Rice TW, Phillips EJ. Risk-stratified Management to Remove Low-Risk Penicillin Allergy Labels in the ICU [letter]. Am. J. Respir. Crit. Care Med. 2020 Jun 6/15/2020; 201(12): 1572-5. PMID: 32083961, PMCID: PMC7301733, DOI: 10.1164/rccm.202001-0089LE, ISSN: 1535-4970.

Khan DA, Phillips EJ. Pharmacogenomic biomarkers in allergy and immunology practice [editorial]. J. Allergy Clin. Immunol [print-electronic]. 2020 Jun 6/10/2020; PMID: 32533972, PII: S0091-6749(20)30827-7, DOI: 10.1016/j.jaci.2020.05.050, ISSN: 1097-6825.

Vyles D, Antoon JW, Norton A, Stone CA, Trubiano J, Radowicz A, Phillips EJ. Children with reported penicillin allergy: Public health impact and safety of delabeling. Ann. Allergy Asthma Immunol [print-electronic]. 2020 Jun; 124(6): 558-65. PMID: 32224207, PMCID: PMC7255916, PII: S1081-1206(20)30156-3, DOI: 10.1016/j.anai.2020.03.012, ISSN: 1534-4436.

Pavlos R, Deshpande P, Chopra A, Leary S, Strautins K, Nolan D, Thorborn D, Shaefer M, Rauch A, Dunn D, Montaner J, Rachlis A, Almeida CA, Choo L, James I, Redwood AJ, Li Y, Gaudieri S, Mallal SA, Phillips EJ. New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals. Hum. Immunol [print-electronic]. 2020 Jun; 81(6): 300-4. PMID: 32173028, PMCID: PMC7266722, PII: S0198-8859(19)31410-7, DOI: 10.1016/j.humimm.2020.02.011, ISSN: 1879-1166.

Nakkam N, Gibson A, Mouhtouris E, Konvinse KC, Holmes N, Chua KY, Deshpande P, Li D, Ostrov DA, Trubiano J, Phillips EJ. Cross-reactivity between vancomycin, teicoplanin, and telavancin in patients with HLA-A*32:01-positive vancomycin-induced DRESS sharing an HLA class II haplotype. J. Allergy Clin. Immunol [print-electronic]. 2020 May 5/19/2020; PMID: 32439433, PII: S0091-6749(20)30687-4, DOI: 10.1016/j.jaci.2020.04.056, ISSN: 1097-6825.

Copaescu A, Rose M, Mouhtouris E, Chua KY, Holmes NE, Phillips EJ, Trubiano JA. Delayed hypersensitivity associated with amoxicillin-clavulanate [letter]. Allergy [print-electronic]. 2020 May 5/10/2020; PMID: 32390163, DOI: 10.1111/all.14359, ISSN: 1398-9995.

Stone CA, Choudhary S, Patterson MF, Rukasin CRF, Coleman DT, Phillips EJ, Commins SP. Tolerance of porcine pancreatic enzymes despite positive skin testing in alpha-gal allergy. J Allergy Clin Immunol Pract [print-electronic]. 2020 May; 8(5): 1728-1732.e1. PMID: 31846796, PMCID: PMC7217730, PII: S2213-2198(19)31024-4, DOI: 10.1016/j.jaip.2019.12.004, ISSN: 2213-2201.

Coleman DT, Stone CA, Wei WQ, Phillips EJ. Readiness for PENicillin allergy testing: Perception of Allergy Label (PEN-PAL) survey. J Allergy Clin Immunol Pract [print-electronic]. 2020 Apr 4/15/2020; PMID: 32304843, PII: S2213-2198(20)30357-3, DOI: 10.1016/j.jaip.2020.03.049, ISSN: 2213-2201.

Castells M, Khan DA, Phillips EJ. Penicillin Allergy. Reply [letter]. N. Engl. J. Med. 2020 Apr 4/2/2020; 382(14): 1380. PMID: 32242379, PII: 10.1056/NEJMc2000115#sa3, DOI: 10.1056/NEJMc2000115, ISSN: 1533-4406.

Chang WC, Abe R, Anderson P, Anderson W, Ardern-Jones MR, Beachkofsky TM, Bellón T, Biala AK, Bouchard C, Cavalleri GL, Chapman N, Chodosh J, Choi HK, Cibotti RR, Divito SJ, Dewar K, Dehaeck U, Etminan M, Forbes D, Fuchs E, Goldman JL, Holmes JH, Hope EA, Hung SI, Hsieh CL, Iovieno A, Jagdeo J, Kim MK, Koelle DM, Lacouture ME, Le Pallec S, Lehloenya RJ, Lim R, Lowe A, McCawley J, McCawley J, Micheletti RG, Mockenhaupt M, Niemeyer K, Norcross MA, Oboh D, Olteanu C, Pasieka HB, Peter J, Pirmohamed M, Rieder M, Saeed HN, Shear NH, Shieh C, Straus S, Sukasem C, Sung C, Trubiano JA, Tsou SY, Ueta M, Volpi S, Wan C, Wang H, Wang ZQ, Weintraub J, Whale C, Wheatley LM, Whyte-Croasdaile S, Williams KB, Wright G, Yeung SN, Zhou L, Chung WH, Phillips EJ, Carleton BC. SJS/TEN 2019: From science to translation. J. Dermatol. Sci [print-electronic]. 2020 Apr; 98(1): 2-12. PMID: 32192826, PMCID: PMC7261636, PII: S0923-1811(20)30064-5, DOI: 10.1016/j.jdermsci.2020.02.003, ISSN: 1873-569X.

Krantz MS, Liu Y, Phillips EJ, Stone CA. Anaphylaxis to PEGylated liposomal echocardiogram contrast in a patient with IgE-mediated macrogol allergy. J Allergy Clin Immunol Pract [print-electronic]. 2020 Apr; 8(4): 1416-1419.e3. PMID: 31954852, PMCID: PMC7263401, PII: S2213-2198(20)30045-3, DOI: 10.1016/j.jaip.2019.12.041, ISSN: 2213-2201.

Trubiano JA, Vogrin S, Chua KYL, Bourke J, Yun J, Douglas A, Stone CA, Yu R, Groenendijk L, Holmes NE, Phillips EJ. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med [print-electronic]. 2020 Mar 3/16/2020; PMID: 32176248, PMCID: PMC7076536, PII: 2762878, DOI: 10.1001/jamainternmed.2020.0403, ISSN: 2168-6114.

Trubiano JA, Chua KYL, Holmes NE, Douglas AP, Mouhtouris E, Goh M, Phillips EJ. Safety of cephalosporins in penicillin class severe delayed hypersensitivity reactions. J Allergy Clin Immunol Pract [print-electronic]. 2020 Mar; 8(3): 1142-1146.e4. PMID: 31678298, PMCID: PMC7064395, PII: S2213-2198(19)30894-3, DOI: 10.1016/j.jaip.2019.10.005, ISSN: 2213-2201.

Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Visotcky A, Fraser R, Pezzin L, Brousseau DC. Oral amoxicillin challenges in low-risk children during a pediatric emergency department visit. J Allergy Clin Immunol Pract [print-electronic]. 2020 Mar; 8(3): 1126-1128.e1. PMID: 31586667, PMCID: PMC7332348, PII: S2213-2198(19)30848-7, DOI: 10.1016/j.jaip.2019.09.022, ISSN: 2213-2201.

Rukasin CRF, Henderlight S, Bosen T, Nelson SD, Phillips EJ. Implications of electronic health record transition on drug allergy labels. J Allergy Clin Immunol Pract [print-electronic]. 2020 Feb; 8(2): 764-6. PMID: 31351188, PMCID: PMC6981006, PII: S2213-2198(19)30634-8, DOI: 10.1016/j.jaip.2019.07.017, ISSN: 2213-2201.

Krantz MS, Stone CA, Abreo A, Phillips EJ. Oral challenge with trimethoprim-sulfamethoxazole in patients with "sulfa" antibiotic allergy. J Allergy Clin Immunol Pract [print-electronic]. 2020 Feb; 8(2): 757-760.e4. PMID: 31319222, PMCID: PMC6960372, PII: S2213-2198(19)30619-1, DOI: 10.1016/j.jaip.2019.07.003, ISSN: 2213-2201.

Stone CA, Trubiano J, Coleman DT, Rukasin CRF, Phillips EJ. The challenge of de-labeling penicillin allergy. Allergy [print-electronic]. 2020 Feb; 75(2): 273-88. PMID: 31049971, PMCID: PMC6824919, DOI: 10.1111/all.13848, ISSN: 1398-9995.

Castells M, Khan DA, Phillips EJ. Penicillin Allergy. N. Engl. J. Med. 2019 Dec 12/12/2019; 381(24): 2338-51. PMID: 31826341, DOI: 10.1056/NEJMra1807761, ISSN: 1533-4406.

Stone CA, Rukasin CRF, Beachkofsky TM, Phillips EJ. Immune-mediated adverse reactions to vaccines. Br J Clin Pharmacol [print-electronic]. 2019 Dec; 85(12): 2694-706. PMID: 31472022, PMCID: PMC6955412, DOI: 10.1111/bcp.14112, ISSN: 1365-2125.

Meher-Homji Z, Tam CS, Siderov J, Seymour JF, Holmes NE, Chua KYL, Phillips EJ, Slavin MA, Trubiano JA. High prevalence of antibiotic allergies in cladribine-treated patients with hairy cell leukemia - lessons for immunopathogenesis and prescribing. Leuk. Lymphoma [print-electronic]. 2019 Dec; 60(14): 3455-60. PMID: 31256738, PMCID: PMC6928424, DOI: 10.1080/10428194.2019.1633640, ISSN: 1029-2403.

Trubiano JA, Ostrov DA, Phillips EJ. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Associated with Carbonic Anhydrase Inhibitors: Epidemiology, Genetics, and Insights into Mechanisms [editorial]. J Allergy Clin Immunol Pract. 2019 Nov; 7(8): 2854-6. PMID: 31706497, PMCID: PMC7255914, PII: S2213-2198(19)30630-0, DOI: 10.1016/j.jaip.2019.07.013, ISSN: 2213-2201.

Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips EJ. Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results. J. Allergy Clin. Immunol [print-electronic]. 2019 Nov; 144(5): 1413-1416.e7. PMID: 31574267, PMCID: PMC7051072, PII: S0091-6749(19)31249-7, DOI: 10.1016/j.jaci.2019.09.013, ISSN: 1097-6825.

Rukasin CRF, Phillips EJ, Norton AE. Slow graded reintroduction of oxcarbazepine for delayed maculopapular eruption. Ann. Allergy Asthma Immunol [print-electronic]. 2019 Oct; 123(4): 411-2. PMID: 31201862, PMCID: PMC6778716, PII: S1081-1206(19)30425-9, DOI: 10.1016/j.anai.2019.06.001, ISSN: 1534-4436.

Trubiano JA, Slavin MA, Thursky KA, Grayson ML, Phillips EJ. Beta-Lactam and Sulfonamide Allergy Testing Should Be a Standard of Care in Immunocompromised Hosts. J Allergy Clin Immunol Pract [print-electronic]. 2019 Sep; 7(7): 2151-3. PMID: 31253580, PMCID: PMC6733665, PII: S2213-2198(19)30547-1, DOI: 10.1016/j.jaip.2019.05.051, ISSN: 2213-2201.

Somogyi AA, Barratt DT, Phillips EJ, Moore K, Ilyas F, Gabb GM. High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms. Br J Clin Pharmacol [print-electronic]. 2019 Sep; 85(9): 2163-9. PMID: 31206740, PMCID: PMC6710506, DOI: 10.1111/bcp.14025, ISSN: 1365-2125.

Rwandamuriye FX, Chopra A, Konvinse KC, Choo L, Trubiano JA, Shaffer CM, Watson M, Mallal SA, Phillips EJ. A Rapid Allele-Specific Assay for HLA-A*32:01 to Identify Patients at Risk for Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms. J Mol Diagn [print-electronic]. 2019 Sep; 21(5): 782-9. PMID: 31158526, PMCID: PMC6734857, PII: S1525-1578(19)30076-5, DOI: 10.1016/j.jmoldx.2019.04.006, ISSN: 1943-7811.

Pan RY, Chu MT, Wang CW, Lee YS, Lemonnier F, Michels AW, Schutte R, Ostrov DA, Chen CB, Phillips EJ, Mallal SA, Mockenhaupt M, Bellón T, Tassaneeyakul W, White KD, Roujeau JC, Chung WH, Hung SI. Identification of drug-specific public TCR driving severe cutaneous adverse reactions. Nat Commun. 2019 Aug 8/8/2019; 10(1): 3569. PMID: 31395875, PMCID: PMC6687717, PII: 10.1038/s41467-019-11396-2, DOI: 10.1038/s41467-019-11396-2, ISSN: 2041-1723.

Trubiano JA, Devchand M, Phillips EJ. Reply [letter]. J Allergy Clin Immunol Pract. 2019 Jul; 7(6): 2095-6. PMID: 31279472, PII: S2213-2198(19)30312-5, DOI: 10.1016/j.jaip.2019.02.047, ISSN: 2213-2201.

Lindestam Arlehamn CS, Pham J, Alcalay RN, Frazier A, Shorr E, Carpenter C, Sidney J, Dhanwani R, Agin-Liebes J, Garretti F, Amara AW, Standaert DG, Phillips EJ, Mallal SA, Peters B, Sulzer D, Sette A. Widespread Tau-Specific CD4 T Cell Reactivity in the General Population. J. Immunol [print-electronic]. 2019 Jul 7/1/2019; 203(1): 84-92. PMID: 31085590, PMCID: PMC6581570, PII: jimmunol.1801506, DOI: 10.4049/jimmunol.1801506, ISSN: 1550-6606.

Konvinse KC, Trubiano JA, Pavlos R, James I, Shaffer CM, Bejan CA, Schutte RJ, Ostrov DA, Pilkinton MA, Rosenbach M, Zwerner JP, Williams KB, Bourke J, Martinez P, Rwandamuriye F, Chopra A, Watson M, Redwood AJ, White KD, Mallal SA, Phillips EJ. HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms. J. Allergy Clin. Immunol [print-electronic]. 2019 Jul; 144(1): 183-92. PMID: 30776417, PMCID: PMC6612297, PII: S0091-6749(19)30210-6, DOI: 10.1016/j.jaci.2019.01.045, ISSN: 1097-6825.

Cook KM, Gillon J, Grisso AG, Banerjee R, Jimenez-Truque N, Phillips EJ, Van Driest SL. Incidence of Nephrotoxicity Among Pediatric Patients Receiving Vancomycin With Either Piperacillin-Tazobactam or Cefepime: A Cohort Study. J Pediatric Infect Dis Soc. 2019 Jul 7/1/2019; 8(3): 221-7. PMID: 29590376, PMCID: PMC6601383, PII: 4953693, DOI: 10.1093/jpids/piy030, ISSN: 2048-7207.

Lammert C, McKinnon EJ, Chalasani N, Phillips EJ. Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis. Clin Transl Gastroenterol. 2019 Jun; 10(6): e00032. PMID: 31211758, PMCID: PMC6613860, DOI: 10.14309/ctg.0000000000000032, ISSN: 2155-384X.

Stone CA, Liu Y, Relling MV, Krantz MS, Pratt AL, Abreo A, Hemler JA, Phillips EJ. Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized. J Allergy Clin Immunol Pract [print-electronic]. 2019 May; 7(5): 1533-1540.e8. PMID: 30557713, PMCID: PMC6706272, PII: S2213-2198(18)30823-7, DOI: 10.1016/j.jaip.2018.12.003, ISSN: 2213-2201.

Trubiano JA, Douglas AP, Goh M, Slavin MA, Phillips EJ. The safety of antibiotic skin testing in severe T-cell-mediated hypersensitivity of immunocompetent and immunocompromised hosts [letter]. J Allergy Clin Immunol Pract [print-electronic]. 2019 Apr; 7(4): 1341-1343.e1. PMID: 30266590, PMCID: PMC6435428, PII: S2213-2198(18)30590-7, DOI: 10.1016/j.jaip.2018.09.014, ISSN: 2213-2201.

Tian Y, Babor M, Lane J, Seumois G, Liang S, Goonawardhana NDS, De Silva AD, Phillips EJ, Mallal SA, da Silva Antunes R, Grifoni A, Vijayanand P, Weiskopf D, Peters B, Sette A. Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles. J. Clin. Invest. 2019 Mar 3/18/2019; 129(4): 1727-41. PMID: 30882366, PMCID: PMC6436856, PII: 123726, DOI: 10.1172/JCI123726, ISSN: 1558-8238.

Devchand M, Urbancic KF, Khumra S, Douglas AP, Smibert O, Cohen E, Sutherland M, Phillips EJ, Trubiano JA. Pathways to improved antibiotic allergy and antimicrobial stewardship practice: The validation of a beta-lactam antibiotic allergy assessment tool. J Allergy Clin Immunol Pract [print-electronic]. 2019 Mar; 7(3): 1063-1065.e5. PMID: 30172019, PMCID: PMC6395557, PII: S2213-2198(18)30528-2, DOI: 10.1016/j.jaip.2018.07.048, ISSN: 2213-2201.

Blumenthal KG, Peter JG, Trubiano JA, Phillips EJ. Antibiotic allergy. Lancet [print-electronic]. 2019 Jan 1/12/2019; 393(10167): 183-98. PMID: 30558872, PMCID: PMC6563335, PII: S0140-6736(18)32218-9, DOI: 10.1016/S0140-6736(18)32218-9, ISSN: 1474-547X.

Karnes JH, Miller MA, White KD, Konvinse KC, Pavlos RK, Redwood AJ, Peter JG, Lehloenya R, Mallal SA, Phillips EJ. Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions. Annu. Rev. Pharmacol. Toxicol [print-electronic]. 2019 Jan 1/6/2019; 59: 463-86. PMID: 30134124, PMCID: PMC6409210, DOI: 10.1146/annurev-pharmtox-010818-021818, ISSN: 1545-4304.

Redwood A, Trubiano J, Phillips EJ. Prevention and Diagnosis of Severe T-Cell-Mediated Adverse Drug Reactions: Are We There Yet? [editorial]. J Allergy Clin Immunol Pract. 2019 Jan; 7(1): 228-30. PMID: 30598178, PMCID: PMC6440535, PII: S2213-2198(18)30445-8, DOI: 10.1016/j.jaip.2018.07.011, ISSN: 2213-2201.

Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, Lehloenya R, Mockenhaupt M, Peter J, Pirmohamed M, Roujeau JC, Shear NH, Tanno LK, Trubiano J, Valluzzi R, Barbaud A. Controversies in drug allergy: Testing for delayed reactions. J. Allergy Clin. Immunol [print-electronic]. 2019 Jan; 143(1): 66-73. PMID: 30573342, PMCID: PMC6429556, PII: S0091-6749(18)31569-0, DOI: 10.1016/j.jaci.2018.10.030, ISSN: 1097-6825.

Phillips EJ. Defining Regional Differences in Drug-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Tool to Improve Drug Safety?. Clin. Pharmacol. Ther [print-electronic]. 2019 Jan; 105(1): 22-5. PMID: 30120778, PMCID: PMC6312457, DOI: 10.1002/cpt.1175, ISSN: 1532-6535.

Stone CA, Commins SP, Choudhary S, Vethody C, Heavrin JL, Wingerter J, Hemler JA, Babe K, Phillips EJ, Norton AE. Anaphylaxis after vaccination in a pediatric patient: further implicating alpha-gal allergy. J Allergy Clin Immunol Pract [print-electronic]. 2019 Jan; 7(1): 322-324.e2. PMID: 29913263, PMCID: PMC6295282, PII: S2213-2198(18)30393-3, DOI: 10.1016/j.jaip.2018.06.005, ISSN: 2213-2201.

Trubiano JA, Smibert O, Douglas A, Devchand M, Lambros B, Holmes NE, Chua KY, Phillips EJ, Slavin MA. The Safety and Efficacy of an Oral Penicillin Challenge Program in Cancer Patients: A Multicenter Pilot Study. Open Forum Infect Dis. 2018 Dec; 5(12): ofy306. PMID: 30547046, PMCID: PMC6287673, PII: ofy306, DOI: 10.1093/ofid/ofy306, ISSN: 2328-8957.

Kim WB, Worley B, Holmes J, Phillips EJ, Beecker J. Minimal clinically important differences for measures of treatment efficacy in Stevens-Johnson syndrome and toxic epidermal necrolysis. J. Am. Acad. Dermatol [print-electronic]. 2018 Dec; 79(6): 1150-2. PMID: 29890189, PMCID: PMC6234072, PII: S0190-9622(18)32057-7, DOI: 10.1016/j.jaad.2018.06.002, ISSN: 1097-6787.

Hulgan T, Dash C, Haas DW, Phillips EJ. Precision HIV care: responding to old questions and meeting new challenges [editorial]. Pharmacogenomics [print-electronic]. 2018 Nov; 19(17): 1299-302. PMID: 30325267, DOI: 10.2217/pgs-2018-0126, ISSN: 1744-8042.

Trubiano JA, Grayson ML, Phillips EJ, Stewardson AJ, Thursky KA, Slavin MA. Antibiotic allergy testing improves antibiotic appropriateness in patients with cancer [letter]. J. Antimicrob. Chemother. 2018 Nov 11/1/2018; 73(11): 3209-11. PMID: 30060208, PMCID: PMC6198745, PII: 5060705, DOI: 10.1093/jac/dky307, ISSN: 1460-2091.

Trubiano JA, Strautins K, Redwood AJ, Pavlos R, Konvinse KC, Aung AK, Slavin MA, Thursky KA, Grayson ML, Phillips EJ. The Combined Utility of Ex Vivo IFN-¿ Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions. J Allergy Clin Immunol Pract [print-electronic]. 2018 Jul; 6(4): 1287-1296.e1. PMID: 29100867, PMCID: PMC5930120, PII: S2213-2198(17)30728-6, DOI: 10.1016/j.jaip.2017.09.004, ISSN: 2213-2201.

Stone CA, Hemler JA, Commins SP, Schuyler AJ, Phillips EJ, Peebles RS, Fahrenholz JM. Reply [letter]. J. Allergy Clin. Immunol [print-electronic]. 2018 May; 141(5): 1957-8. PMID: 29370925, PMCID: PMC6298749, PII: S0091-6749(17)31891-2, DOI: 10.1016/j.jaci.2017.08.048, ISSN: 1097-6825.

Norton AE, Konvinse K, Phillips EJ, Broyles AD. Antibiotic Allergy in Pediatrics. Pediatrics. 2018 May; 141(5): PMID: 29700201, PMCID: PMC5914499, PII: peds.2017-2497, DOI: 10.1542/peds.2017-2497, ISSN: 1098-4275.

Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Kibicho J, Brousseau DC. Antibiotic Use After Removal of Penicillin Allergy Label. Pediatrics. 2018 May; 141(5): PMID: 29678929, PMCID: PMC5914488, PII: peds.2017-3466, DOI: 10.1542/peds.2017-3466, ISSN: 1098-4275.

Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL, Mushiroda T, Klein T, Gammal RS, Pirmohamed M. Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update. Clin. Pharmacol. Ther [print-electronic]. 2018 Apr; 103(4): 574-81. PMID: 29392710, PMCID: PMC5847474, DOI: 10.1002/cpt.1004.

Manolio TA, Hutter CM, Avigan M, Cibotti R, Davis RL, Denny JC, Grenade L, Wheatley LM, Carrington MN, Chantratita W, Chung WH, Dalton AD, Hung SI, Lee MTM, Leeder JS, Lertora JJL, Mahasirimongkol S, McLeod HL, Mockenhaupt M, Pacanowski M, Phillips EJ, Pinheiro S, Pirmohamed M, Sung C, Suwankesawong W, Trepanier L, Tumminia SJ, Veenstra D, Yuliwulandari R, Shear NH. Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis. Clin. Pharmacol. Ther [print-electronic]. 2018 Mar; 103(3): 390-4. PMID: 29105735, PMCID: PMC5805563, DOI: 10.1002/cpt.890, ISSN: 1532-6535.

White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ. SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. J Allergy Clin Immunol Pract. 2018 Jan; 6(1): 38-69. PMID: 29310768, PMCID: PMC5857362, PII: S2213-2198(17)30911-X, DOI: 10.1016/j.jaip.2017.11.023, ISSN: 2213-2201.

Redwood AJ, Pavlos RK, White KD, Phillips EJ. HLAs: Key regulators of T-cell-mediated drug hypersensitivity. HLA. 2018 Jan; 91(1): 3-16. PMID: 29171940, PMCID: PMC5743596, DOI: 10.1111/tan.13183, ISSN: 2059-2310.

Derrick MI, Williams KB, Shade LMP, Phillips EJ. A survey of drug allergy training opportunities in the United States. J Allergy Clin Immunol Pract [print-electronic]. 2018 Jan; 6(1): 302-4. PMID: 28958742, PMCID: PMC5760283, PII: S2213-2198(17)30612-8, DOI: 10.1016/j.jaip.2017.08.003, ISSN: 2213-2201.

Trubiano JA, Adkinson NF, Phillips EJ. Persistence of Penicillin Allergy-Reply [letter]. JAMA. 2017 Nov 11/7/2017; 318(17): 1714-5. PMID: 29114827, PII: 2661574, DOI: 10.1001/jama.2017.13763, ISSN: 1538-3598.

Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA. Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects. J. Immunol [print-electronic]. 2017 Nov 11/1/2017; 199(9): 3187-201. PMID: 28972094, PMCID: PMC5679304, PII: jimmunol.1700851, DOI: 10.4049/jimmunol.1700851, ISSN: 1550-6606.

Pavlos R, White KD, Wanjalla C, Mallal SA, Phillips EJ. Severe Delayed Drug Reactions: Role of Genetics and Viral Infections. Immunol Allergy Clin North Am. 2017 Nov; 37(4): 785-815. PMID: 28965641, PMCID: PMC5702581, PII: S0889-8561(17)30080-2, DOI: 10.1016/j.iac.2017.07.007, ISSN: 1557-8607.

Trubiano JA, Stone CA, Grayson ML, Urbancic K, Slavin MA, Thursky KA, Phillips EJ. The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration. J Allergy Clin Immunol Pract [print-electronic]. 2017 Nov; 5(6): 1532-42. PMID: 28843343, PMCID: PMC5681410, PII: S2213-2198(17)30501-9, DOI: 10.1016/j.jaip.2017.06.017, ISSN: 2213-2201.

Garon SL, Pavlos RK, White KD, Brown NJ, Stone CA, Phillips EJ. Pharmacogenomics of off-target adverse drug reactions. Br J Clin Pharmacol [print-electronic]. 2017 Sep; 83(9): 1896-911. PMID: 28345177, PMCID: PMC5555876, DOI: 10.1111/bcp.13294, ISSN: 1365-2125.

Pavlos R, McKinnon EJ, Ostrov DA, Peters B, Buus S, Koelle D, Chopra A, Schutte R, Rive C, Redwood A, Restrepo S, Bracey A, Kaever T, Myers P, Speers E, Malaker SA, Shabanowitz J, Jing Y, Gaudieri S, Hunt DF, Carrington M, Haas DW, Mallal S, Phillips EJ. Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles. Sci Rep. 2017 Aug 8/17/2017; 7(1): 8653. PMID: 28819312, PMCID: PMC5561238, PII: 10.1038/s41598-017-08876-0, DOI: 10.1038/s41598-017-08876-0, ISSN: 2045-2322.

Karnes JH, Shaffer CM, Cronin R, Bastarache L, Gaudieri S, James I, Pavlos R, Steiner H, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Influence of human leukocyte antigen (HLA) alleles and killer cell immunoglobulin-like receptors (KIR) types on heparin-induced thrombocytopenia (HIT). Pharmacotherapy [print-electronic]. 2017 Jul 7/8/2017; PMID: 28688202, DOI: 10.1002/phar.1983, ISSN: 1875-9114.

Trubiano JA, Adkinson NF, Phillips EJ. Penicillin Allergy Is Not Necessarily Forever. JAMA. 2017 Jul 7/4/2017; 318(1): 82-3. PMID: 28672303, PII: 2635615, DOI: 10.1001/jama.2017.6510, ISSN: 1538-3598.

Tseng A, Hughes CA, Wu J, Seet J, Phillips EJ. Cobicistat Versus Ritonavir: Similar Pharmacokinetic Enhancers But Some Important Differences. Ann Pharmacother [print-electronic]. 2017 Jun 6/1/2017; 1060028017717018. PMID: 28627229, DOI: 10.1177/1060028017717018, ISSN: 1542-6270.

Trubiano JA, Thursky KA, Stewardson AJ, Urbancic K, Worth LJ, Jackson C, Stevenson W, Sutherland M, Slavin MA, Grayson ML, Phillips EJ. Impact of an Integrated Antibiotic Allergy Testing Program on Antimicrobial Stewardship: A Multicenter Evaluation. Clin. Infect. Dis [print-electronic]. 2017 May 5/18/2017; PMID: 28520865, PII: 3832923, DOI: 10.1093/cid/cix244, ISSN: 1537-6591.

Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC. Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Sci Transl Med. 2017 May 5/10/2017; 9(389): PMID: 28490672, PII: 9/389/eaai8708, DOI: 10.1126/scitranslmed.aai8708, ISSN: 1946-6242.

Stone CA, Hemler JA, Commins SP, Schuyler AJ, Phillips EJ, Peebles RS, Fahrenholz JM. Anaphylaxis after zoster vaccine: Implicating alpha-gal allergy as a possible mechanism. J. Allergy Clin. Immunol [print-electronic]. 2017 May; 139(5): 1710-1713.e2. PMID: 27986511, PMCID: PMC5420485, PII: S0091-6749(16)31455-5, DOI: 10.1016/j.jaci.2016.10.037, ISSN: 1097-6825.

Peter JG, Lehloenya R, Dlamini S, Risma K, White KD, Konvinse KC, Phillips EJ. Severe Delayed Cutaneous and Systemic Reactions to Drugs: A Global Perspective on the Science and Art of Current Practice. J Allergy Clin Immunol Pract. 2017 May; 5(3): 547-63. PMID: 28483310, PMCID: PMC5424615, PII: S2213-2198(17)30046-6, DOI: 10.1016/j.jaip.2017.01.025, ISSN: 2213-2201.

Adler NR, Aung AK, Ergen EN, Trubiano J, Goh MS, Phillips EJ. Recent advances in the understanding of severe cutaneous adverse reactions. Br. J. Dermatol [print-electronic]. 2017 Mar 3/3/2017; PMID: 28256714, DOI: 10.1111/bjd.15423, ISSN: 1365-2133.

Karnes JH, Shaffer CM, Bastarache L, Gaudieri S, Glazer AM, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Comparison of HLA allelic imputation programs. PLoS ONE. 2017; 12(2): e0172444. PMID: 28207879, PMCID: PMC5312875, PII: PONE-D-16-48785, DOI: 10.1371/journal.pone.0172444, ISSN: 1932-6203.

Konvinse KC, Phillips EJ, White KD, Trubiano JA. Old dog begging for new tricks: current practices and future directions in the diagnosis of delayed antimicrobial hypersensitivity. Curr. Opin. Infect. Dis. 2016 Dec; 29(6): 561-76. PMID: 27753687, PMCID: PMC5113146, DOI: 10.1097/QCO.0000000000000323, ISSN: 1473-6527.

Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA, Anders RA, Sosman JA, Moslehi JJ. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. N. Engl. J. Med. 2016 Nov 11/3/2016; 375(18): 1749-55. PMID: 27806233, PMCID: PMC5247797, DOI: 10.1056/NEJMoa1609214, ISSN: 1533-4406.

Trubiano JA, Beekmann SE, Worth LJ, Polgreen PM, Thursky KA, Slavin MA, Grayson ML, Phillips EJ. Improving Antimicrobial Stewardship by Antibiotic Allergy Delabeling: Evaluation of Knowledge, Attitude, and Practices Throughout the Emerging Infections Network. Open Forum Infect Dis. 2016 Sep; 3(3): ofw153. PMID: 27800527, PMCID: PMC5084721, PII: ofw153, DOI: 10.1093/ofid/ofw153, ISSN: 2328-8957.

Murray TS, Rice TW, Wheeler AP, Phillips EJ, Dworski RT, Stollings JL. Medication Desensitization: Characterization of Outcomes and Risk Factors for Reactions. Ann Pharmacother [print-electronic]. 2016 Mar; 50(3): 203-8. PMID: 26783356, PII: 1060028015625660, DOI: 10.1177/1060028015625660, ISSN: 1542-6270.

Jing L, Laing KJ, Dong L, Russell RM, Barlow RS, Haas JG, Ramchandani MS, Johnston C, Buus S, Redwood AJ, White KD, Mallal SA, Phillips EJ, Posavad CM, Wald A, Koelle DM. Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses. J. Immunol [print-electronic]. 2016 Mar 3/1/2016; 196(5): 2205-18. PMID: 26810224, PMCID: PMC4761520, PII: jimmunol.1502366, DOI: 10.4049/jimmunol.1502366, ISSN: 1550-6606.

Phillips EJ. Classifying ADRs--does dose matter?. Br J Clin Pharmacol [print-electronic]. 2016 Jan; 81(1): 10-2. PMID: 26286675, PMCID: PMC4693569, DOI: 10.1111/bcp.12749, ISSN: 1365-2125.

Saito Y, Stamp LK, Caudle KE, Hershfield MS, McDonagh EM, Callaghan JT, Tassaneeyakul W, Mushiroda T, Kamatani N, Goldspiel BR, Phillips EJ, Klein TE, Lee MT, . Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update. Clin. Pharmacol. Ther [print-electronic]. 2016 Jan; 99(1): 36-7. PMID: 26094938, PMCID: PMC4675696, DOI: 10.1002/cpt.161.

Hemler JA, Phillips EJ, Mallal SA, Kendall PL. The evolving story of human leukocyte antigen and the immunogenetics of peanut allergy. Ann. Allergy Asthma Immunol [print-electronic]. 2015 Dec; 115(6): 471-6. PMID: 26522257, PII: S1081-1206(15)00693-6, DOI: 10.1016/j.anai.2015.10.008, ISSN: 1534-4436.

Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA. Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy. J. Allergy Clin. Immunol. 2015 Aug; 136(2): 262-71.e2. PMID: 26254053, PMCID: PMC4529958, PII: S0091-6749(15)00733-2, DOI: 10.1016/j.jaci.2015.05.027, ISSN: 1097-6825.

White KD, Chung WH, Hung SI, Mallal S, Phillips EJ. Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response. J. Allergy Clin. Immunol. 2015 Aug; 136(2): 219-34; quiz 235. PMID: 26254049, PMCID: PMC4577472, PII: S0091-6749(15)00869-6, DOI: 10.1016/j.jaci.2015.05.050, ISSN: 1097-6825.

Milpied-Homsi B, Moran EM, Phillips EJ. Antiviral drug allergy. Immunol Allergy Clin North Am. 2014 Aug; 34(3): 645-62, ix. PMID: 25017682, PMCID: PMC4140860, PII: S0889-8561(14)00059-9, DOI: 10.1016/j.iac.2014.04.011, ISSN: 1557-8607.

Stone SF, Phillips EJ, Wiese MD, Heddle RJ, Brown SG. Immediate-type hypersensitivity drug reactions. Br J Clin Pharmacol. 2014 Jul; 78(1): 1-13. PMID: 24286446, PMCID: PMC4168374, DOI: 10.1111/bcp.12297, ISSN: 1365-2125.

Brusch AM, Clarke RC, Platt PR, Phillips EJ. Exploring the link between pholcodine exposure and neuromuscular blocking agent anaphylaxis. Br J Clin Pharmacol. 2014 Jul; 78(1): 14-23. PMID: 24251966, PMCID: PMC4168376, DOI: 10.1111/bcp.12290, ISSN: 1365-2125.

Karlin E, Phillips E. Genotyping for severe drug hypersensitivity. Curr Allergy Asthma Rep. 2014 Mar; 14(3): 418. PMID: 24429903, PMCID: PMC4014135, DOI: 10.1007/s11882-013-0418-0, ISSN: 1534-6315.

Trubiano J, Phillips E. Antimicrobial stewardship's new weapon? A review of antibiotic allergy and pathways to 'de-labeling'. Curr. Opin. Infect. Dis. 2013 Dec; 26(6): 526-37. PMID: 24126717, PMCID: PMC3862073, DOI: 10.1097/QCO.0000000000000006, ISSN: 1473-6527.

Rive CM, Bourke J, Phillips EJ. Testing for drug hypersensitivity syndromes. Clin Biochem Rev. 2013 Feb; 34(1): 15-38. PMID: 23592889, PMCID: PMC3626363, ISSN: 0159-8090.

Phillips EJ, Mallal SA. HLA-B*5701 and flucloxacillin associated drug-induced liver disease [letter]. AIDS. 2013 Jan 1/28/2013; 27(3): 491-2. PMID: 23291545, PII: 00002030-201301280-00025, DOI: 10.1097/QAD.0b013e32835ca9d5, ISSN: 1473-5571.

Lee MH, Stocker SL, Anderson J, Phillips EJ, Nolan D, Williams KM, Graham GG, Sullivan JR, Day RO. Initiating allopurinol therapy: do we need to know the patient's human leucocyte antigen status?. Intern Med J. 2012 Apr; 42(4): 411-6. PMID: 21790926, DOI: 10.1111/j.1445-5994.2011.02567.x, ISSN: 1445-5994.

Pavlos R, Phillips EJ. Individualization of antiretroviral therapy. Pharmgenomics Pers Med [print-electronic]. 2012; 5: 1-17. PMID: 23226059, PMCID: PMC3513193, PII: pgpm-5-001, DOI: 10.2147/PGPM.S15303, ISSN: 1178-7066.

Haas DW, Kuritzkes DR, Ritchie MD, Amur S, Gage BF, Maartens G, Masys D, Fellay J, Phillips E, Ribaudo HJ, Freedberg KA, Petropoulos C, Manolio TA, Gulick RM, Haubrich R, Kim P, Dehlinger M, Abebe R, Telenti A, . Pharmacogenomics of HIV therapy: summary of a workshop sponsored by the National Institute of Allergy and Infectious Diseases. HIV Clin Trials. 2011 Sep; 12(5): 277-85. PMID: 22180526, PMCID: PMC3322423, PII: H4HV83200516XH08, DOI: 10.1310/hct1205-277, ISSN: 1528-4336.

Phillips EJ, Mallal SA. HLA-B*1502 screening and toxic effects of carbamazepine [letter]. N. Engl. J. Med. 2011 Aug 8/18/2011; 365(7): 672; author reply 673. PMID: 21848472, DOI: 10.1056/NEJMc1105467#SA1, ISSN: 1533-4406.

Phillips EJ, Chung WH, Mockenhaupt M, Roujeau JC, Mallal SA. Drug hypersensitivity: pharmacogenetics and clinical syndromes. J. Allergy Clin. Immunol. 2011 Mar; 127(3 Suppl): S60-6. PMID: 21354501, PMCID: PMC3061439, PII: S0091-6749(10)01943-3, DOI: 10.1016/j.jaci.2010.11.046, ISSN: 1097-6825.

Phillips EJ, Mallal SA. Pharmacogenetics of drug hypersensitivity. Pharmacogenomics. 2010 Jul; 11(7): 973-87. PMID: 20602616, PMCID: PMC2937181, DOI: 10.2217/pgs.10.77, ISSN: 1744-8042.

Phillips EJ, Mallal SA. HLA and drug-induced toxicity. Curr. Opin. Mol. Ther. 2009 Jun; 11(3): 231-42. PMID: 19479656, ISSN: 2040-3445.

Shear NH, Milpied B, Bruynzeel DP, Phillips EJ. A review of drug patch testing and implications for HIV clinicians. AIDS. 2008 May 5/31/2008; 22(9): 999-1007. PMID: 18520343, PII: 00002030-200805310-00001, DOI: 10.1097/QAD.0b013e3282f7cb60, ISSN: 1473-5571.

Phillips EJ, Mallal SA. Pharmacogenetics and the potential for the individualization of antiretroviral therapy. Curr. Opin. Infect. Dis. 2008 Feb; 21(1): 16-24. PMID: 18192781, PII: 00001432-200802000-00005, DOI: 10.1097/QCO.0b013e3282f42224, ISSN: 0951-7375.

Tansey CM, Louie M, Loeb M, Gold WL, Muller MP, de Jager J, Cameron JI, Tomlinson G, Mazzulli T, Walmsley SL, Rachlis AR, Mederski BD, Silverman M, Shainhouse Z, Ephtimios IE, Avendano M, Downey J, Styra R, Yamamura D, Gerson M, Stanbrook MB, Marras TK, Phillips EJ, Zamel N, Richardson SE, Slutsky AS, Herridge MS. One-year outcomes and health care utilization in survivors of severe acute respiratory syndrome. Arch. Intern. Med. 2007 Jun 6/25/2007; 167(12): 1312-20. PMID: 17592106, PII: 167/12/1312, DOI: 10.1001/archinte.167.12.1312, ISSN: 0003-9926.

Chui CK, Brumme ZL, Brumme CJ, Yip B, Phillips EJ, Montaner JS, Harrigan PR. A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase. Clin. Infect. Dis [print-electronic]. 2007 Jun 6/1/2007; 44(11): 1503-8. PMID: 17479950, PII: CID41502, DOI: 10.1086/517499, ISSN: 1537-6591.

Phillips EJ. Genetic screening to prevent abacavir hypersensitivity reaction: are we there yet? [editorial]. Clin. Infect. Dis [print-electronic]. 2006 Jul 7/1/2006; 43(1): 103-5. PMID: 16758425, PII: CID39675, DOI: 10.1086/504878, ISSN: 1537-6591.

Phillips EJ. The pharmacogenetics of antiretroviral therapy. Curr Opin HIV AIDS. 2006 May; 1(3): 249-56. PMID: 19372817, PII: 01222929-200605000-00012, DOI: 10.1097/01.COH.0000221600.64659.d3, ISSN: 1746-6318.

Tailor SA, Simor AE, Cornish W, Phillips EJ, Knowles S, Rachlis A. Glucose homeostasis abnormalities and gatifloxacin [letter]. Clin. Infect. Dis. 2006 Mar 3/15/2006; 42(6): 895. PMID: 16477578, PII: CID38665, DOI: 10.1086/500454, ISSN: 1537-6591.

Notman MJ, Phillips EJ, Knowles SR, Weber EA, Shear NH. Clindamycin skin testing has limited diagnostic potential. Contact Derm. 2005 Dec; 53(6): 335-8. PMID: 16364122, PII: COD716, DOI: 10.1111/j.0105-1873.2005.00716.x, ISSN: 0105-1873.

Antoniou T, Tseng AL, van Heeswijk RP, Walker SE, Giguere P, Phillips EJ. Steady-state pharmacokinetics and tolerability of indinavir-lopinavir/r combination therapy in antiretroviral-experienced patients. Ther Drug Monit. 2005 Dec; 27(6): 779-81. PMID: 16306854, PII: 00007691-200512000-00021, ISSN: 0163-4356.

van Heeswijk RP, Cooper CL, Foster BC, Chauhan BM, Shirazi F, Seguin I, Phillips EJ, Mills E. Effect of high-dose vitamin C on hepatic cytochrome P450 3A4 activity. Pharmacotherapy. 2005 Dec; 25(12): 1725-8. PMID: 16305291, DOI: 10.1592/phco.2005.25.12.1725, ISSN: 0277-0008.