Anthony B. Daniels, M.D.

Assistant Professor

anthony.b.daniels@vanderbilt.edu
Faculty Appointments
Assistant Professor of Ophthalmology and Visual Sciences Assistant Professor of Radiation Oncology
Education
M.D., Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaM.S.H.S., London School of Economics, London, United KingdomB.A., Princeton University, Princeton, New Jersey
Publications
Johnson DB, Daniels AB. Continued Poor Survival in Metastatic Uveal Melanoma: Implications for Molecular Prognostication, Surveillance Imaging, Adjuvant Therapy, and Clinical Trials. JAMA Ophthalmol [print-electronic]. 2018 Jun 6/28/2018; PMID: 29955760, PII: 2686114, DOI: 10.1001/jamaophthalmol.2018.1813, ISSN: 2168-6173.

Arreola A, Payne LB, Julian MH, de Cubas AA, Daniels AB, Taylor S, Zhao H, Darden J, Bautch VL, Rathmell WK, Chappell JC. Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch. JCI Insight [print-electronic]. 2018 Feb 2/22/2018; 3(4): PMID: 29467323, PMCID: PMC5916240, PII: 92193, DOI: 10.1172/jci.insight.92193, ISSN: 2379-3708.

Braue JA, Daniels AB, Zwerner JP, Kim SJ, Zic JA. Intraocular involvement of mycosis fungoides associated with immunophenotypic switch from CD4+ to CD8 [letter]. Blood [print-electronic]. 2018 Feb 2/22/2018; 131(8): 932-5. PMID: 29298755, PMCID: PMC5824338, PII: blood-2017-11-814194, DOI: 10.1182/blood-2017-11-814194, ISSN: 1528-0020.

Daniels AB, Froehler MT, Pierce JM, Nunnally AH, Calcutt MW, Bridges TM, LaNeve DC, Williams PE, Boyd KL, Reyzer ML, Lindsley CW, Friedman DL, Richmond A. Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma. Invest. Ophthalmol. Vis. Sci. 2018 Jan 1/1/2018; 59(1): 446-54. PMID: 29368001, PMCID: PMC5783625, PII: 2670512, DOI: 10.1167/iovs.17-22302, ISSN: 1552-5783.

Scelfo C, Francis JH, Khetan V, Jenkins T, Marr B, Abramson DH, Shields CL, Pe'er J, Munier F, Berry J, Harbour JW, Yarovoy A, Lucena E, Murray TG, Bhagia P, Paysse E, Tuncer S, Chantada GL, Moll AC, Ushakova T, Plager DA, Ziyovuddin I, Leal CA, Materin MA, Ji XD, Cursino JW, Polania R, Kiratli H, All-Ericsson C, Kebudi R, Honavar SG, Vishnevskia-Dai V, Epelman S, Daniels AB, Ling JD, Traore F, Ramirez-Ortiz MA. An international survey of classification and treatment choices for group D retinoblastoma. Int J Ophthalmol. 2017; 10(6): 961-7. PMID: 28730089, PMCID: PMC5515152, PII: ijo-10-06-961, DOI: 10.18240/ijo.2017.06.20, ISSN: 2222-3959.

Daniels AB, Mukai S. Modern Surgical Techniques in the Management of Retinoblastoma. Int Ophthalmol Clin. 2017; 57(1): 195-218. PMID: 27898624, PII: 00004397-201705710-00016, DOI: 10.1097/IIO.0000000000000151, ISSN: 1536-9617.

Yuan S, Friedman DL, Daniels AB. Alternative Chemotherapeutic Agents for the Treatment of Retinoblastoma Using the Intra-Arterial and Intravitreal Routes: A Path Forward Toward Drug Discovery. Int Ophthalmol Clin. 2017; 57(1): 129-41. PMID: 27898619, PII: 00004397-201705710-00011, DOI: 10.1097/IIO.0000000000000154, ISSN: 1536-9617.

Yuan S, Friedman DL, Daniels AB. Evolution of Chemotherapy Approaches for the Treatment of Intraocular Retinoblastoma: A Comprehensive Review. Int Ophthalmol Clin. 2017; 57(1): 117-28. PMID: 27898618, PII: 00004397-201705710-00010, DOI: 10.1097/IIO.0000000000000155, ISSN: 1536-9617.

Batson SA, Breazzano MP, Milam RW, Shinohara E, Johnson DB, Daniels AB. Rationale for Harnessing the Abscopal Effect as Potential Treatment for Metastatic Uveal Melanoma. Int Ophthalmol Clin. 2017; 57(1): 41-8. PMID: 27898612, PII: 00004397-201705710-00004, DOI: 10.1097/IIO.0000000000000152, ISSN: 1536-9617.

Breazzano MP, Milam RW, Batson SA, Johnson DB, Daniels AB. Immunotherapy for Uveal Melanoma. Int Ophthalmol Clin. 2017; 57(1): 29-39. PMID: 27898611, PII: 00004397-201705710-00003, DOI: 10.1097/IIO.0000000000000148, ISSN: 1536-9617.

Milam RW, Batson SA, Breazzano MP, Ayala-Peacock DN, Daniels AB. Modern and Novel Radiotherapy Approaches for the Treatment of Uveal Melanoma. Int Ophthalmol Clin. 2017; 57(1): 11-27. PMID: 27898610, PII: 00004397-201705710-00002, DOI: 10.1097/IIO.0000000000000153, ISSN: 1536-9617.

Nichols EE, Richmond A, Daniels AB. Micrometastatic Dormancy in Uveal Melanoma: A Comprehensive Review of the Evidence, Mechanisms, and Implications for Future Adjuvant Therapies. Int Ophthalmol Clin. 2017; 57(1): 1-10. PMID: 27898609, PII: 00004397-201705710-00001, DOI: 10.1097/IIO.0000000000000160, ISSN: 1536-9617.

Ling J, Tauscher R, Mehta V, Zhang M, Daniels A, Kohanim S. The Role for Sentinel Lymph Node Biopsy in the Management of Conjunctival Melanoma. Int Ophthalmol Clin. 2017; 57(1): 87-101. PMID: 27898616, PII: 00004397-201705710-00008, DOI: 10.1097/IIO.0000000000000161, ISSN: 1536-9617.

Hollar MW, Zhang MM, Daniels A, Kohanim S. Mechanisms Underlying the Absence of Cancers of the Human Crystalline Lens. Int Ophthalmol Clin. 2017; 57(1): 49-56. PMID: 27898613, PII: 00004397-201705710-00005, DOI: 10.1097/IIO.0000000000000159, ISSN: 1536-9617.

Zhang MM, Papakostas TD, Malcolm AW, Ancell KK, Biscotti CV, Gragoudas ES, Daniels AB. Multiple simultaneous choroidal melanomas arising in the same eye: globe salvage by radiotherapy. Acta Ophthalmol [print-electronic]. 2016 Dec; 94(8): e799-e802. PMID: 27079925, DOI: 10.1111/aos.13034, ISSN: 1755-3768.

Vavvas DG, Daniels AB, Kapsala ZG, Goldfarb JW, Ganotakis E, Loewenstein JI, Young LH, Gragoudas ES, Eliott D, Kim IK, Tsilimbaris MK, Miller JW. Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment. EBioMedicine. 2016 Mar; 5: 198-203. PMID: 27077128, PMCID: PMC4816836, PII: S2352-3964(16)30029-9, DOI: 10.1016/j.ebiom.2016.01.033, ISSN: 2352-3964.

Daniels AB, Nathan NR, Kohanim S. Disparities in Eye Health and Disease: Where Are We in 2016? [editorial]. Semin Ophthalmol [print-electronic]. 2016; 31(4): 295. PMID: 27328174, DOI: 10.3109/08820538.2016.1154760, ISSN: 1744-5205.

Nichols EE, Richmond A, Daniels AB. Tumor Characteristics, Genetics, Management, and the Risk of Metastasis in Uveal Melanoma. Semin Ophthalmol [print-electronic]. 2016; 31(4): 304-9. PMID: 27128983, PMCID: PMC5526754, DOI: 10.3109/08820538.2016.1154175, ISSN: 1744-5205.

Nichols EE, Richmond A, Daniels AB. Disparities in Uveal Melanoma: Patient Characteristics. Semin Ophthalmol [print-electronic]. 2016; 31(4): 296-303. PMID: 27128153, PMCID: PMC5441550, DOI: 10.3109/08820538.2016.1154176, ISSN: 1744-5205.

Singh G, Daniels AB. Disparities in Retinoblastoma Presentation, Treatment, and Outcomes in Developed and Less-Developed Countries. Semin Ophthalmol [print-electronic]. 2016; 31(4): 310-6. PMID: 27127937, DOI: 10.3109/08820538.2016.1154177, ISSN: 1744-5205.

Abramson DH, Daniels AB, Marr BP, Francis JH, Brodie SE, Dunkel IJ, Gobin YP. Intra-Arterial Chemotherapy (Ophthalmic Artery Chemosurgery) for Group D Retinoblastoma. PLoS ONE. 2016; 11(1): e0146582. PMID: 26756643, PMCID: PMC4710506, PII: PONE-D-15-39039, DOI: 10.1371/journal.pone.0146582, ISSN: 1932-6203.

Ling JD, Mehta V, Fathy C, Rapoport Y, Zhang MM, Daniels A, Kohanim S. Racial Disparities in Corneal Transplantation Rates, Complications, and Outcomes. Semin Ophthalmol [print-electronic]. 2016; 31(4): 337-44. PMID: 27092728, DOI: 10.3109/08820538.2016.1154162, ISSN: 1744-5205.

Taubenslag KJ, Kim SJ, Attia A, Abel TW, Nickols HH, Ancell KK, Daniels AB. Retinal metastasis from unknown primary: diagnosis, management, and clinicopathologic correlation. Digit J Ophthalmol. 2015; 21(4): 1-10. PMID: 27330472, PMCID: PMC4902637, PII: djo-14-110, DOI: 10.5693/djo.02.2015.04.004, ISSN: 1542-8958.

Patel MM, Jakobiec FA, Zakka FR, Du R, Annino DJ, Borboli-Gerogiannis S, Daniels AB. Intraorbital metastasis from solitary fibrous tumor. Ophthal Plast Reconstr Surg. 2013 May; 29(3): e76-9. PMID: 23328780, DOI: 10.1097/IOP.0b013e318272f311, ISSN: 1537-2677.

Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK. High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2012 Oct; 53(11): 6991-6. PMID: 22977135, PMCID: PMC3471553, PII: iovs.12-10427, DOI: 10.1167/iovs.12-10427, ISSN: 1552-5783.

Kohanim S, Daniels AB, Huynh N, Eliott D, Chodosh J. Utility of ocular ultrasonography in diagnosing infectious endophthalmitis in patients with media opacities. Semin Ophthalmol. 2012 Sep; 27(5-6): 242-5. PMID: 23163283, DOI: 10.3109/08820538.2012.711417, ISSN: 1744-5205.

Daniels AB, Kohanim S. An introduction to advances in ocular imaging [editorial]. Semin Ophthalmol. 2012 Sep; 27(5-6): 99. PMID: 23163260, DOI: 10.3109/08820538.2012.722500, ISSN: 1744-5205.

Daniels AB, Sandberg MA, Chen J, Weigel-DiFranco C, Fielding Hejtmancic J, Berson EL. Genotype-phenotype correlations in Bardet-Biedl syndrome. Arch. Ophthalmol. 2012 Jul; 130(7): 901-7. PMID: 22410627, PII: archophthalmol.2012.89, DOI: 10.1001/archophthalmol.2012.89, ISSN: 1538-3601.

Kohanim S, Daniels AB, Huynh N, Chodosh J. Local treatment of Kaposi sarcoma of the conjunctiva. Int Ophthalmol Clin. 2011; 51(4): 183-92. PMID: 21897150, PII: 00004397-201105140-00018, DOI: 10.1097/IIO.0b013e31822d68e8, ISSN: 1536-9617.

Huynh N, Daniels AB, Kohanim S, Young LH. Medical treatment for cytomegalovirus retinitis. Int Ophthalmol Clin. 2011; 51(4): 93-103. PMID: 21897143, PII: 00004397-201105140-00011, DOI: 10.1097/IIO.0b013e31822d6834, ISSN: 1536-9617.

Daniels AB, Kohanim S, Huynh N, Durand ML, Young LH. Antiviral chemoprophylaxis for ocular viral infections in hematopoietic stem cell and bone marrow transplant patients. Int Ophthalmol Clin. 2011; 51(4): 53-66. PMID: 21897140, PII: 00004397-201105140-00008, DOI: 10.1097/IIO.0b013e31822d65e9, ISSN: 1536-9617.

Daniels AB, Jakobiec FA, Westerfeld CB, Hagiwara A, Michaud N, Mukai S. Idiopathic subfoveal choroidal neovascular membrane in a 21-month-old child: ultrastructural features and implication for membranogenesis. J AAPOS [print-electronic]. 2010 Jun; 14(3): 244-50. PMID: 20417139, PII: S1091-8531(10)00071-6, DOI: 10.1016/j.jaapos.2010.01.010, ISSN: 1528-3933.

Daniels AB, Worth RG, Dickstein RJ, Dickstein JS, Kim-Han TH, Kim MK, Schreiber AD. Analysis of FcgammaRIIA cytoplasmic tail requirements in signaling for serotonin secretion: evidence for an ITAM-dependent, PI3K-dependent pathway. Scand. J. Immunol. 2010 Apr; 71(4): 232-9. PMID: 20384866, PMCID: PMC2855141, PII: SJI2369, DOI: 10.1111/j.1365-3083.2010.02369.x, ISSN: 1365-3083.

Daniels AB, Miller ML, Kotecha A, Abramson DH. Uveal metastasis from nonsmall cell lung carcinoma with dramatic response to erlotinib. Retin Cases Brief Rep. 2010; 4(4): 390-3. PMID: 25390927, PII: 01271216-201000440-00029, DOI: 10.1097/ICB.0b013e3181e180e6, ISSN: 1935-1089.

Daniels AB, Brodie SE, Abramson DH. Spontaneous resolution of total retinal detachment in coats disease. Retin Cases Brief Rep. 2010; 4(2): 206-9. PMID: 25390404, PII: 01271216-201000420-00033, DOI: 10.1097/ICB.0b013e3181ad3927, ISSN: 1935-1089.

Mowry EM, Loguidice MJ, Daniels AB, Jacobs DA, Markowitz CE, Galetta SL, Nano-Schiavi ML, Cutter GR, Maguire MG, Balcer LJ. Vision related quality of life in multiple sclerosis: correlation with new measures of low and high contrast letter acuity. J. Neurol. Neurosurg. Psychiatr [print-electronic]. 2009 Jul; 80(7): 767-72. PMID: 19240050, PII: jnnp.2008.165449, DOI: 10.1136/jnnp.2008.165449, ISSN: 1468-330X.

Daniels AB, Abramson DH. C-KIT in uveal melanoma: big fish or red herring? [editorial]. Arch. Ophthalmol. 2009 May; 127(5): 695-7. PMID: 19433723, PII: 127/5/695, DOI: 10.1001/archophthalmol.2009.49, ISSN: 1538-3601.

Bonhomme GR, Waldman AT, Balcer LJ, Daniels AB, Tennekoon GI, Forman S, Galetta SL, Liu GT. Pediatric optic neuritis: brain MRI abnormalities and risk of multiple sclerosis. Neurology. 2009 Mar 3/10/2009; 72(10): 881-5. PMID: 19273821, PII: 72/10/881, DOI: 10.1212/01.wnl.0000344163.65326.48, ISSN: 1526-632X.

Daniels AB, Liu GT, Volpe NJ, Galetta SL, Moster ML, Newman NJ, Biousse V, Lee AG, Wall M, Kardon R, Acierno MD, Corbett JJ, Maguire MG, Balcer LJ. Profiles of obesity, weight gain, and quality of life in idiopathic intracranial hypertension (pseudotumor cerebri). Am. J. Ophthalmol. 2007 Apr; 143(4): 635-41. PMID: 17386271, PII: S0002-9394(07)00004-9, DOI: 10.1016/j.ajo.2006.12.040, ISSN: 0002-9394.

Available Postdoctoral Position Details
Posted: 7/26/2018

Two postdoctoral positions are available immediately in the laboratory of Dr. Anthony Daniels in the Department of Ophthalmology and the Vanderbilt-Ingram Cancer Center at Vanderbilt University Medical Center in Nashville, Tennessee. The laboratory is nurturing, hard working and fast-paced, and the successful postdocs will find flexibility to pursue their exciting ideas with quite a bit of independence. Both positions already have full funding and are available immediately.

Postdoctoral Position #1: We are seeking a highly motivated scientist with extensive experience working with mouse models, and in particular, experience with injection or microdissection of mouse eyes. The successful candidate would balance two projects using mouse models of disease and treatment. One project is related to the intrinsic biology of ocular cancers and the other project is related to drug discovery for the treatment of ocular cancer.

Postdoctoral Position #2: We are seeking a highly motivated scientist with experience in molecular, cell, or developmental biology. The project involves utilizing extensive multi-institutional data on genotype-phenotype correlations in eye cancers as well as data on proteomic networks. The successful candidate will design and implement experiments that assess the effect of specific cellular pathways on tumor cell behavior.

Both successful candidates must have a PhD in Biological Sciences or the equivalent with at least one first-author publication from their graduate work and strong research background in molecular, cell or developmental biology. Candidates with less than 2 years of postgraduate work are specifically encouraged to apply. To apply, email a brief cover letter describing research accomplishments and future research goals, current CV with list of publications, and contact information for 3 professional references to: anthony.b.daniels@vanderbilt.edu. Please specify which one of the two positions you are applying for.

Due to restrictions related to federal funding, applicants must either be U.S. citizens or permanent residents (green card holders) at the time they apply. Please confirm this in your application email.