Faculty Appointments
Associate Professor of Medicine
Education
M.D., Loma Linda University, Loma Linda, CaliforniaB.Sc., Southern Adventist University , Collegedale, Tennessee
Publications
Tadros J, Chastain C, Tkaczyk E. Diffuse painful plaques in the setting of chronic lymphocytic leukemia. Cutis. 2020 Aug; 106(2): E18-E20. PMID: 32941567, DOI: 10.12788/cutis.0075, ISSN: 2326-6929.
Tadros J, Chastain CA, Tkaczyk E. Colonic and perianal ulceration exhibiting vacuolar interface dermatitis in the setting of HIV. Clin Case Rep. 2019 Aug; 7(8): 1478-80. PMID: 31428371, PMCID: PMC6692980, PII: CCR32222, DOI: 10.1002/ccr3.2222, ISSN: 2050-0904.
Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi C, Xu Y, Moslehi JJ, Sanders ME, Sosman JA, Balko JM. A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis. Nat Med [print-electronic]. 2019 Aug; 25(8): 1243-50. PMID: 31332390, PMCID: PMC6689251, PII: 10.1038/s41591-019-0523-2, DOI: 10.1038/s41591-019-0523-2, ISSN: 1546-170X.
Chastain CA, Klopfenstein N, Serezani CH, Aronoff DM. A Clinical Review of Diabetic Foot Infections. Clin Podiatr Med Surg [print-electronic]. 2019 Jul; 36(3): 381-95. PMID: 31079605, PII: S0891-8422(19)30016-3, DOI: 10.1016/j.cpm.2019.02.004, ISSN: 1558-2302.
Zuckerman AD, Douglas A, Whelchel K, Choi L, DeClercq J, Chastain CA. Pharmacologic management of HCV treatment in patients with HCV monoinfection vs. HIV/HCV coinfection: Does coinfection really matter?. PLoS One. 2019; 14(11): e0225434. PMID: 31751399, PMCID: PMC6872158, PII: PONE-D-19-23601, DOI: 10.1371/journal.pone.0225434, ISSN: 1932-6203.
Lucas M, Deshpande P, James I, Rauch A, Pfafferott K, Gaylard E, Merani S, Plauzolles A, Lucas A, McDonnell W, Kalams S, Pilkinton M, Chastain C, Barnett L, Prosser A, Mallal S, Fitzmaurice K, Drummer H, Ansari MA, Pedergnana V, Barnes E, John M, Kelleher D, Klenerman P, Gaudieri S. Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome. Sci Rep. 2018 May 5/8/2018; 8(1): 7224. PMID: 29740042, PMCID: PMC5940905, PII: 10.1038/s41598-018-25559-6, DOI: 10.1038/s41598-018-25559-6, ISSN: 2045-2322.
Zuckerman A, Douglas A, Nwosu S, Choi L, Chastain C. Increasing success and evolving barriers in the hepatitis C cascade of care during the direct acting antiviral era. PLoS One. 2018; 13(6): e0199174. PMID: 29912944, PMCID: PMC6005558, PII: PONE-D-18-09237, DOI: 10.1371/journal.pone.0199174, ISSN: 1932-6203.
Zuckerman A, Carver A, Chastain CA. Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes. Curr Treat Options Infect Dis [print-electronic]. 2018; 10(4): 431-46. PMID: 30524209, PMCID: PMC6244618, PII: 177, DOI: 10.1007/s40506-018-0177-5, ISSN: 1523-3820.
Chastain CA, Beekmann SE, Wallender EK, Hulgan T, Stapleton JT, Polgreen PM. Hepatitis C Management and the Infectious Diseases Physician: A Survey of Current and Anticipated Practice Patterns. Clin. Infect. Dis [print-electronic]. 2015 Sep 9/1/2015; 61(5): 792-4. PMID: 25979310, PII: civ384, DOI: 10.1093/cid/civ384, ISSN: 1537-6591.
Jones W, Chastain CA, Wright PW. Iatrogenic cushing syndrome secondary to a probable interaction between voriconazole and budesonide. Pharmacotherapy [print-electronic]. 2014 Jul; 34(7): e116-9. PMID: 24757038, DOI: 10.1002/phar.1432, ISSN: 1875-9114.
Chastain CA, Naggie S. Treatment of genotype 1 HCV infection in the HIV coinfected patient in 2014. Curr HIV/AIDS Rep. 2013 Dec; 10(4): 408-19. PMID: 24272069, PMCID: PMC4892376, DOI: 10.1007/s11904-013-0182-8, ISSN: 1548-3576.
Bratton EW, El Husseini N, Chastain CA, Lee MS, Poole C, Stürmer T, Weber DJ, Juliano JJ, Perfect JR. Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis. Antimicrob. Agents Chemother [print-electronic]. 2013 Jun; 57(6): 2485-95. PMID: 23478968, PMCID: PMC3716133, PII: AAC.01800-12, DOI: 10.1128/AAC.01800-12, ISSN: 1098-6596.
Chastain CA, Cox GM, Powers MA. Dyspnea and hypoxia in a 64-year-old male traveler. Chest. 2012 Aug; 142(2): 532-5. PMID: 22871766, PII: S0012-3692(12)60471-1, DOI: 10.1378/chest.11-2654, ISSN: 1931-3543.
Bratton EW, El Husseini N, Chastain CA, Lee MS, Poole C, Stürmer T, Juliano JJ, Weber DJ, Perfect JR. Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative/non-transplant. PLoS ONE [print-electronic]. 2012; 7(8): e43582. PMID: 22937064, PMCID: PMC3427358, PII: PONE-D-12-08841, DOI: 10.1371/journal.pone.0043582, ISSN: 1932-6203.
Chen LF, Chastain C, Anderson DJ. Community-Acquired Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: Management and Prevention. Curr Infect Dis Rep. 2011 Oct; 13(5): 442-50. PMID: 21773687, DOI: 10.1007/s11908-011-0198-4, ISSN: 1534-3146.
Chastain CA, Oyoyo UE, Zipperman M, Joo E, Ashwal S, Shutter LA, Tong KA. Predicting outcomes of traumatic brain injury by imaging modality and injury distribution. J. Neurotrauma. 2009 Aug; 26(8): 1183-96. PMID: 19317591, DOI: 10.1089/neu.2008.0650, ISSN: 1557-9042.
Chastain CA, Eck JC, Hodges SD, Humphreys SC, Levi P. Transforaminal lumbar interbody fusion: a retrospective study of long-term pain relief and fusion outcomes. Orthopedics. 2007 May; 30(5): 389-92. PMID: 17539212, ISSN: 0147-7447.
Tadros J, Chastain CA, Tkaczyk E. Colonic and perianal ulceration exhibiting vacuolar interface dermatitis in the setting of HIV. Clin Case Rep. 2019 Aug; 7(8): 1478-80. PMID: 31428371, PMCID: PMC6692980, PII: CCR32222, DOI: 10.1002/ccr3.2222, ISSN: 2050-0904.
Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi C, Xu Y, Moslehi JJ, Sanders ME, Sosman JA, Balko JM. A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis. Nat Med [print-electronic]. 2019 Aug; 25(8): 1243-50. PMID: 31332390, PMCID: PMC6689251, PII: 10.1038/s41591-019-0523-2, DOI: 10.1038/s41591-019-0523-2, ISSN: 1546-170X.
Chastain CA, Klopfenstein N, Serezani CH, Aronoff DM. A Clinical Review of Diabetic Foot Infections. Clin Podiatr Med Surg [print-electronic]. 2019 Jul; 36(3): 381-95. PMID: 31079605, PII: S0891-8422(19)30016-3, DOI: 10.1016/j.cpm.2019.02.004, ISSN: 1558-2302.
Zuckerman AD, Douglas A, Whelchel K, Choi L, DeClercq J, Chastain CA. Pharmacologic management of HCV treatment in patients with HCV monoinfection vs. HIV/HCV coinfection: Does coinfection really matter?. PLoS One. 2019; 14(11): e0225434. PMID: 31751399, PMCID: PMC6872158, PII: PONE-D-19-23601, DOI: 10.1371/journal.pone.0225434, ISSN: 1932-6203.
Lucas M, Deshpande P, James I, Rauch A, Pfafferott K, Gaylard E, Merani S, Plauzolles A, Lucas A, McDonnell W, Kalams S, Pilkinton M, Chastain C, Barnett L, Prosser A, Mallal S, Fitzmaurice K, Drummer H, Ansari MA, Pedergnana V, Barnes E, John M, Kelleher D, Klenerman P, Gaudieri S. Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome. Sci Rep. 2018 May 5/8/2018; 8(1): 7224. PMID: 29740042, PMCID: PMC5940905, PII: 10.1038/s41598-018-25559-6, DOI: 10.1038/s41598-018-25559-6, ISSN: 2045-2322.
Zuckerman A, Douglas A, Nwosu S, Choi L, Chastain C. Increasing success and evolving barriers in the hepatitis C cascade of care during the direct acting antiviral era. PLoS One. 2018; 13(6): e0199174. PMID: 29912944, PMCID: PMC6005558, PII: PONE-D-18-09237, DOI: 10.1371/journal.pone.0199174, ISSN: 1932-6203.
Zuckerman A, Carver A, Chastain CA. Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes. Curr Treat Options Infect Dis [print-electronic]. 2018; 10(4): 431-46. PMID: 30524209, PMCID: PMC6244618, PII: 177, DOI: 10.1007/s40506-018-0177-5, ISSN: 1523-3820.
Chastain CA, Beekmann SE, Wallender EK, Hulgan T, Stapleton JT, Polgreen PM. Hepatitis C Management and the Infectious Diseases Physician: A Survey of Current and Anticipated Practice Patterns. Clin. Infect. Dis [print-electronic]. 2015 Sep 9/1/2015; 61(5): 792-4. PMID: 25979310, PII: civ384, DOI: 10.1093/cid/civ384, ISSN: 1537-6591.
Jones W, Chastain CA, Wright PW. Iatrogenic cushing syndrome secondary to a probable interaction between voriconazole and budesonide. Pharmacotherapy [print-electronic]. 2014 Jul; 34(7): e116-9. PMID: 24757038, DOI: 10.1002/phar.1432, ISSN: 1875-9114.
Chastain CA, Naggie S. Treatment of genotype 1 HCV infection in the HIV coinfected patient in 2014. Curr HIV/AIDS Rep. 2013 Dec; 10(4): 408-19. PMID: 24272069, PMCID: PMC4892376, DOI: 10.1007/s11904-013-0182-8, ISSN: 1548-3576.
Bratton EW, El Husseini N, Chastain CA, Lee MS, Poole C, Stürmer T, Weber DJ, Juliano JJ, Perfect JR. Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis. Antimicrob. Agents Chemother [print-electronic]. 2013 Jun; 57(6): 2485-95. PMID: 23478968, PMCID: PMC3716133, PII: AAC.01800-12, DOI: 10.1128/AAC.01800-12, ISSN: 1098-6596.
Chastain CA, Cox GM, Powers MA. Dyspnea and hypoxia in a 64-year-old male traveler. Chest. 2012 Aug; 142(2): 532-5. PMID: 22871766, PII: S0012-3692(12)60471-1, DOI: 10.1378/chest.11-2654, ISSN: 1931-3543.
Bratton EW, El Husseini N, Chastain CA, Lee MS, Poole C, Stürmer T, Juliano JJ, Weber DJ, Perfect JR. Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative/non-transplant. PLoS ONE [print-electronic]. 2012; 7(8): e43582. PMID: 22937064, PMCID: PMC3427358, PII: PONE-D-12-08841, DOI: 10.1371/journal.pone.0043582, ISSN: 1932-6203.
Chen LF, Chastain C, Anderson DJ. Community-Acquired Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: Management and Prevention. Curr Infect Dis Rep. 2011 Oct; 13(5): 442-50. PMID: 21773687, DOI: 10.1007/s11908-011-0198-4, ISSN: 1534-3146.
Chastain CA, Oyoyo UE, Zipperman M, Joo E, Ashwal S, Shutter LA, Tong KA. Predicting outcomes of traumatic brain injury by imaging modality and injury distribution. J. Neurotrauma. 2009 Aug; 26(8): 1183-96. PMID: 19317591, DOI: 10.1089/neu.2008.0650, ISSN: 1557-9042.
Chastain CA, Eck JC, Hodges SD, Humphreys SC, Levi P. Transforaminal lumbar interbody fusion: a retrospective study of long-term pain relief and fusion outcomes. Orthopedics. 2007 May; 30(5): 389-92. PMID: 17539212, ISSN: 0147-7447.