Jane F. Ferguson, Ph.D.

My research focuses on the genetics of cardiometabolic diseases, with a particular focus on functional genomics and clinical translation. I am interested in the interactions between genetic and environmental factors in disease development, and in the use of evoked phenotypes as a tool for genomic discovery. My current research projects include: 1) Understanding the determinants of alpha-aminoadipic acid and its relationship to cardiometabolic disease; 2) Novel metabolomic biomarkers of disease; 3) The interaction between diet and the microbiome in cardiometabolic risk.

Bagheri M, Tanriverdi K, Iafrati MD, Mosley JD, Freedman JE, Ferguson JF. Characterization of the plasma metabolome and lipidome in response to sleeve gastrectomy and gastric bypass surgeries reveals molecular patterns of surgical weight loss. Metabolism [print-electronic]. 2024 Sep; 158: 155955. PMID: 38906372, PII: S0026-0495(24)00182-3, DOI: 10.1016/j.metabol.2024.155955, ISSN: 1532-8600.

Antonetti OR, Desine S, Smith HM, Robles ME, McDonald E, Ovide G, Wang C, Dean ED, Doran AC, Calcutt MW, Huang S, Brown JD, Silver HJ, Ferguson JF. The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA). Nutr Metab Cardiovasc Dis [print-electronic]. 2024 Jul; 34(7): 1712-20. PMID: 38658223, PMCID: PMC11188583, PII: S0939-4753(24)00111-X, DOI: 10.1016/j.numecd.2024.03.009, ISSN: 1590-3729.

Mosley JD, Shi M, Agamasu D, Vaitinadin NS, Murthy VL, Shah RV, Bagheri M, Ferguson JF. Branched-chain amino acids and type 2 diabetes: a bidirectional Mendelian randomization analysis. Obesity (Silver Spring). 2024 Feb; 32(2): 423-35. PMID: 38269471, PMCID: PMC10827349, DOI: 10.1002/oby.23951, ISSN: 1930-739X.

Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ, Ferguson JF, Wells QS, Mosley JD. Identification of Clinical Drivers of Left Atrial Enlargement Through Genomics of Left Atrial Size. Circ Heart Fail [print-electronic]. 2024 Jan; 17(1): e010557. PMID: 38126226, PMCID: PMC10842187, DOI: 10.1161/CIRCHEARTFAILURE.123.010557, ISSN: 1941-3297.

Bagheri M, Bombin A, Shi M, Murthy VL, Shah R, Mosley JD, Ferguson JF. Genotype-based "virtual" metabolomics in a clinical biobank identifies novel metabolite-disease associations. Front Genet. 2024; 15: 1392622. PMID: 38812968, PMCID: PMC11133605, PII: 1392622, DOI: 10.3389/fgene.2024.1392622, ISSN: 1664-8021.

Bagheri M, Bombin A, Shi M, Murthy VL, Shah R, Mosley JD, Ferguson JF. Genotype-based "virtual" metabolomics in a clinical biobank identifies novel metabolite-disease associations. Res Sq. 2023 Oct 10/11/2023; PMID: 37790512, PMCID: PMC10543429, PII: rs.3.rs-3222588, DOI: 10.21203/rs.3.rs-3222588/v2, ISSN: 2693-5015.

Bagheri M, Agrawal V, Annis J, Shi M, Ferguson JF, Freiberg MS, Mosley JD, Brittain EL. Genetics of Pulmonary Pressure and Right Ventricle Stress Identify Diabetes as a Causal Risk Factor. J Am Heart Assoc [print-electronic]. 2023 Aug; 12(15): e029190. PMID: 37522172, PMCID: PMC10492967, DOI: 10.1161/JAHA.122.029190, ISSN: 2047-9980.

Gabriel CL, Ferguson JF. Gut Microbiota and Microbial Metabolism in Early Risk of Cardiometabolic Disease. Circ Res [print-electronic]. 2023 Jun 6/9/2023; 132(12): 1674-91. PMID: 37289901, PMCID: PMC10254080, DOI: 10.1161/CIRCRESAHA.123.322055, ISSN: 1524-4571.

Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals. MedRxiv. 2023 Jun 6/6/2023; PMID: 37333170, PMCID: PMC10274998, PII: 2023.06.05.23290990, DOI: 10.1101/2023.06.05.23290990.

Ishimwe JA, Ferguson JF, Kirabo A. Sex Differences in Fatty Acid Metabolism and Blood Pressure Response to Dietary Salt in Humans. Cardiogenetics [print-electronic]. 2023 Mar; 13(1): 33-46. PMID: 38605973, PMCID: PMC11008634, DOI: 10.3390/cardiogenetics13010005, ISSN: 2035-8253.

Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals. Front Endocrinol (Lausanne). 2023; 14: 1122391. PMID: 37745703, PMCID: PMC10513411, DOI: 10.3389/fendo.2023.1122391, ISSN: 1664-2392.

Li J, George Markowitz RH, Brooks AW, Mallott EK, Leigh BA, Olszewski T, Zare H, Bagheri M, Smith HM, Friese KA, Habibi I, Lawrence WM, Rost CL, Lédeczi Á, Eeds AM, Ferguson JF, Silver HJ, Bordenstein SR. Individuality and ethnicity eclipse a short-term dietary intervention in shaping microbiomes and viromes. PLoS Biol. 2022 Aug; 20(8): e3001758. PMID: 35998206, PMCID: PMC9397868, PII: PBIOLOGY-D-21-02097, DOI: 10.1371/journal.pbio.3001758, ISSN: 1545-7885.

Markowitz RHG, LaBella AL, Shi M, Rokas A, Capra JA, Ferguson JF, Mosley JD, Bordenstein SR. Microbiome-associated human genetic variants impact phenome-wide disease risk. Proc Natl Acad Sci U S A [print-electronic]. 2022 Jun 6/28/2022; 119(26): e2200551119. PMID: 35749358, PMCID: PMC9245617, DOI: 10.1073/pnas.2200551119, ISSN: 1091-6490.

Shi M, Wang C, Mei H, Temprosa M, Florez JC, Tripputi M, Merino J, Lipworth L, Shu XO, Gerszten RE, Wang TJ, Beckman JA, Gamboa JL, Mosley JD, Ferguson JF, . Genetic Architecture of Plasma Alpha-Aminoadipic Acid Reveals a Relationship With High-Density Lipoprotein Cholesterol. J Am Heart Assoc [print-electronic]. 2022 Jun 6/7/2022; 11(11): e024388. PMID: 35621206, PMCID: PMC9238724, DOI: 10.1161/JAHA.121.024388, ISSN: 2047-9980.

Bailin SS, Gabriel CL, Fan R, Ye F, Nair S, Terry JG, Carr JJ, Silver H, Wanjalla CN, Mashayekhi M, Lima M, Woodward B, Hannah L, Fuseini H, Ferguson JF, Kropski JA, Koethe JR. Relationship of Subcutaneous Adipose Tissue Inflammation-Related Gene Expression With Ectopic Lipid Deposition in Persons With HIV. J Acquir Immune Defic Syndr. 2022 Jun 6/1/2022; 90(2): 175-83. PMID: 35125474, PMCID: PMC9203874, PII: 00126334-202206010-00009, DOI: 10.1097/QAI.0000000000002926, ISSN: 1944-7884.

Bombin A, Yan S, Bombin S, Mosley JD, Ferguson JF. Obesity influences composition of salivary and fecal microbiota and impacts the interactions between bacterial taxa. Physiol Rep. 2022 Apr; 10(7): e15254. PMID: 35384379, PMCID: PMC8980904, DOI: 10.14814/phy2.15254, ISSN: 2051-817X.

Bagheri M, Shah RD, Mosley JD, Ferguson JF. A metabolome and microbiome wide association study of healthy eating index points to the mechanisms linking dietary pattern and metabolic status. Eur J Nutr [print-electronic]. 2021 Dec; 60(8): 4413-27. PMID: 34057579, PMCID: PMC8572162, PII: 10.1007/s00394-021-02599-9, DOI: 10.1007/s00394-021-02599-9, ISSN: 1436-6215.

Ferguson JF. A microbial metabolite linked to fat accumulation. Nat Metab. 2021 Dec; 3(12): 1594-5. PMID: 34931083, PII: 10.1038/s42255-021-00495-4, DOI: 10.1038/s42255-021-00495-4, ISSN: 2522-5812.

Bagheri M, Wang C, Shi M, Manouchehri A, Murray KT, Murphy MB, Shaffer CM, Singh K, Davis LK, Jarvik GP, Stanaway IB, Hebbring S, Reilly MP, Gerszten RE, Wang TJ, Mosley JD, Ferguson JF. The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene. Sci Rep. 2021 Aug 8/2/2021; 11(1): 15652. PMID: 34341450, PMCID: PMC8329184, PII: 10.1038/s41598-021-95154-9, DOI: 10.1038/s41598-021-95154-9, ISSN: 2045-2322.

Wang NC, Bagheri M, Olszewski T, Friese KA, Smith HM, Robles ME, Wang C, Brooks A, Bordenstein SR, Ferguson JF, Silver HJ. New-onset vegetarian diet shows differences in fatty acid metabolites in European American and African American women. Nutr Metab Cardiovasc Dis [print-electronic]. 2021 Jul 7/22/2021; 31(8): 2436-48. PMID: 34176710, PMCID: PMC10317312, PII: S0939-4753(21)00236-2, DOI: 10.1016/j.numecd.2021.05.013, ISSN: 1590-3729.

Gabriel CL, Ye F, Fan R, Nair S, Terry JG, Carr JJ, Silver H, Baker P, Hannah L, Wanjalla C, Mashayekhi M, Bailin S, Lima M, Woodward B, Izzy M, Ferguson JF, Koethe JR. Hepatic Steatosis and Ectopic Fat Are Associated With Differences in Subcutaneous Adipose Tissue Gene Expression in People With HIV. Hepatol Commun. 2021 Jul; 5(7): 1224-37. PMID: 34278171, PMCID: PMC8279464, PII: 02009842-202107000-00010, DOI: 10.1002/hep4.1695, ISSN: 2471-254X.

Shi M, Manouchehri AM, Shaffer CM, Vaitinadin NS, Hellwege JN, Salem JE, Davis LK, Simmons JH, Roden DM, Shoemaker MB, Ferguson JF, Mosley JD. Genetic Thyrotropin Regulation of Atrial Fibrillation Risk Is Mediated Through an Effect on Height. J Clin Endocrinol Metab. 2021 Jun 6/16/2021; 106(7): 2124-32. PMID: 33895829, PMCID: PMC8208678, PII: 6250092, DOI: 10.1210/clinem/dgab272, ISSN: 1945-7197.

Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS, Cai Z, Biswas S, Trégouët DA, Smith NL, , , , Seldin M, Pan C, Mehrabian M, Lusis AJ, Bazeley P, Sun YV, Liu C, Quyyumi AA, Scholz M, Thiery J, Delgado GE, Kleber ME, März W, Howe LJ, Asselbergs FW, van Vugt M, Vlachojannis GJ, Patel RS, Lyytikäinen LP, Kähönen M, Lehtimäki T, Nieminen TVM, Kuukasjärvi P, Laurikka JO, Chang X, Heng CK, Jiang R, Kraus WE, Hauser ER, Ferguson JF, Reilly MP, Ito K, Koyama S, Kamatani Y, Komuro I, , Stolze LK, Romanoski CE, Khan MD, Turner AW, Miller CL, Aherrahrou R, Civelek M, Ma L, Björkegren JLM, Kumar SR, Tang WHW, Hazen SL, Allayee H. Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Eur Heart J. 2021 Mar 3/1/2021; 42(9): 919-33. PMID: 33532862, PMCID: PMC7936531, PII: 6126843, DOI: 10.1093/eurheartj/ehaa1040, ISSN: 1522-9645.

Overby HB, Ferguson JF. Gut Microbiota-Derived Short-Chain Fatty Acids Facilitate Microbiota:Host Cross talk and Modulate Obesity and Hypertension. Curr Hypertens Rep. 2021 Feb 2/3/2021; 23(2): 8. PMID: 33537923, PMCID: PMC7992370, PII: 10.1007/s11906-020-01125-2, DOI: 10.1007/s11906-020-01125-2, ISSN: 1534-3111.

Wang C, Calcutt MW, Ferguson JF. Knock-Out of DHTKD1 Alters Mitochondrial Respiration and Function, and May Represent a Novel Pathway in Cardiometabolic Disease Risk. Front Endocrinol (Lausanne). 2021; 12: 710698. PMID: 34484123, PMCID: PMC8414881, DOI: 10.3389/fendo.2021.710698, ISSN: 1664-2392.

Beckman JA, Hu JR, Huang S, Farber-Eger E, Wells QS, Wang TJ, Gerszten RE, Ferguson JF. Metabolomics reveals the impact of Type 2 diabetes on local muscle and vascular responses to ischemic stress. Clin Sci (Lond). 2020 Sep 9/18/2020; 134(17): 2369-79. PMID: 32880388, PMCID: PMC8176641, PII: 226294, DOI: 10.1042/CS20191227, ISSN: 1470-8736.

Elijovich F, Laffer CL, Sahinoz M, Pitzer A, Ferguson JF, Kirabo A. The Gut Microbiome, Inflammation, and Salt-Sensitive Hypertension. Curr Hypertens Rep. 2020 Sep 9/3/2020; 22(10): 79. PMID: 32880753, PMCID: PMC7471100, PII: 10.1007/s11906-020-01091-9, DOI: 10.1007/s11906-020-01091-9, ISSN: 1534-3111.

Shah RD, Tang ZZ, Chen G, Huang S, Ferguson JF. Soy food intake associates with changes in the metabolome and reduced blood pressure in a gut microbiota dependent manner. Nutr Metab Cardiovasc Dis [print-electronic]. 2020 Aug 8/28/2020; 30(9): 1500-11. PMID: 32620337, PMCID: PMC7483644, PII: S0939-4753(20)30155-1, DOI: 10.1016/j.numecd.2020.05.001, ISSN: 1590-3729.

Fish-Trotter H, Ferguson JF, Patel N, Arora P, Allen NB, Bachmann KN, Daniels LB, Reilly MP, Lima JAC, Wang TJ, Gupta DK. Inflammation and Circulating Natriuretic Peptide Levels. Circ Heart Fail [print-electronic]. 2020 Jul; 13(7): e006570. PMID: 32507024, PMCID: PMC7375923, DOI: 10.1161/CIRCHEARTFAILURE.119.006570, ISSN: 1941-3297.

Ferguson J. Maternal microbial molecules affect offspring health. Science. 2020 Feb 2/28/2020; 367(6481): 978-9. PMID: 32108100, PII: 367/6481/978, DOI: 10.1126/science.aba7673, ISSN: 1095-9203.

Chen ZZ, Liu J, Morningstar J, Heckman-Stoddard BM, Lee CG, Dagogo-Jack S, Ferguson JF, Hamman RF, Knowler WC, Mather KJ, Perreault L, Florez JC, Wang TJ, Clish C, Temprosa M, Gerszten RE, . Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program. Diabetes [print-electronic]. 2019 Oct 10/3/2019; PMID: 31582408, PII: db19-0236, DOI: 10.2337/db19-0236, ISSN: 1939-327X.

Tuteja S, Ferguson JF. Gut Microbiome and Response to Cardiovascular Drugs. Circ Genom Precis Med [print-electronic]. 2019 Sep; 12(9): 421-9. PMID: 31462078, PMCID: PMC6751004, DOI: 10.1161/CIRCGEN.119.002314, ISSN: 2574-8300.

Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, Chen G, Reilly MP, Kirabo A. High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension. JCI Insight. 2019 Jun 6/4/2019; 5: PMID: 31162138, PMCID: PMC6629246, PII: 126241, DOI: 10.1172/jci.insight.126241, ISSN: 2379-3708.

Wells QS, Gupta DK, Smith JG, Collins SP, Storrow AB, Ferguson J, Smith ML, Pulley JM, Collier S, Wang X, Roden DM, Gerszten RE, Wang TJ. Accelerating Biomarker Discovery Through Electronic Health Records, Automated Biobanking, and Proteomics. J. Am. Coll. Cardiol. 2019 May 5/7/2019; 73(17): 2195-205. PMID: 31047008, PMCID: PMC6501811, PII: S0735-1097(19)33945-2, DOI: 10.1016/j.jacc.2019.01.074, ISSN: 1558-3597.

Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, O'Flaherty M, Pandey A, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Spartano NL, Stokes A, Tirschwell DL, Tsao CW, Turakhia MP, VanWagner LB, Wilkins JT, Wong SS, Virani SS, . Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019 Mar 3/5/2019; 139(10): e56-e528. PMID: 30700139, DOI: 10.1161/CIR.0000000000000659, ISSN: 1524-4539.

Tang ZZ, Chen G, Hong Q, Huang S, Smith HM, Shah RD, Scholz M, Ferguson JF. Multi-Omic Analysis of the Microbiome and Metabolome in Healthy Subjects Reveals Microbiome-Dependent Relationships Between Diet and Metabolites. Front Genet. 2019; 10: 454. PMID: 31164901, PMCID: PMC6534069, DOI: 10.3389/fgene.2019.00454, ISSN: 1664-8021.

Mohammadkhah AI, Simpson EB, Patterson SG, Ferguson JF. Development of the Gut Microbiome in Children, and Lifetime Implications for Obesity and Cardiometabolic Disease. Children (Basel). 2018 Nov 11/27/2018; 5(12): PMID: 30486462, PMCID: PMC6306821, PII: children5120160, DOI: 10.3390/children5120160, ISSN: 2227-9067.

Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Kitchner TE, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Kiryluk K, Mentch FD, Sleiman PM, Karlson EW, Verma SS, Zhu Y, Vasan RS, Yang Q, Denny JC, Roden DM, Gerszten RE, Wang TJ. Probing the Virtual Proteome to Identify Novel Disease Biomarkers. Circulation. 2018 Nov 11/27/2018; 138(22): 2469-81. PMID: 30571344, DOI: 10.1161/CIRCULATIONAHA.118.036063, ISSN: 1524-4539.

Ferguson JF, Xue C, Gao Y, Tian T, Shi J, Zhang X, Wang Y, Li YD, Wei Z, Li M, Zhang H, Reilly MP. Tissue-Specific Differential Expression of Novel Genes and Long Intergenic Noncoding RNAs in Humans With Extreme Response to Evoked Endotoxemia. Circ Genom Precis Med. 2018 Nov; 11(11): e001907. PMID: 30571184, PMCID: PMC6309423, DOI: 10.1161/CIRCGEN.117.001907, ISSN: 2574-8300.

Ferguson JF, Roberts-Lee K, Borcea C, Smith HM, Midgette Y, Shah R. Omega-3 polyunsaturated fatty acids attenuate inflammatory activation and alter differentiation in human adipocytes. J. Nutr. Biochem [print-electronic]. 2018 Oct 10/11/2018; 64: 45-9. PMID: 30428424, PII: S0955-2863(18)30295-X, DOI: 10.1016/j.jnutbio.2018.09.027, ISSN: 1873-4847.

Feng Q, Wei WQ, Chung CP, Levinson RT, Sundermann AC, Mosley JD, Bastarache L, Ferguson JF, Cox NJ, Roden DM, Denny JC, Linton MF, Edwards DRV, Stein CM. Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. PLoS Med. 2018 Aug; 15(8): e1002642. PMID: 30153257, PMCID: PMC6112635, PII: PMEDICINE-D-17-03325, DOI: 10.1371/journal.pmed.1002642, ISSN: 1549-1676.

Zhang X, Xue C, Lin J, Ferguson JF, Weiner A, Liu W, Han Y, Hinkle C, Li W, Jiang H, Gosai S, Hachet M, Garcia BA, Gregory BD, Soccio RE, Hogenesch JB, Seale P, Li M, Reilly MP. Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism. Sci Transl Med. 2018 Jun 6/20/2018; 10(446): PMID: 29925637, PII: 10/446/eaar5987, DOI: 10.1126/scitranslmed.aar5987, ISSN: 1946-6242.

Musunuru K, Arora P, Cooke JP, Ferguson JF, Hershberger RE, Hickey KT, Lee JM, Lima JAC, Loscalzo J, Pereira NL, Russell MW, Shah SH, Sheikh F, Wang TJ, MacRae CA, . Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2018 Jun; 11(6): e000046. PMID: 29844141, PII: HCG.0000000000000046, DOI: 10.1161/HCG.0000000000000046, ISSN: 2574-8300.

Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jiménez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O'Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P, . Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. Circulation [print-electronic]. 2018 Mar 3/20/2018; 137(12): e67-e492. PMID: 29386200, PII: CIR.0000000000000558, DOI: 10.1161/CIR.0000000000000558, ISSN: 1524-4539.

Bachmann KN, Deger SM, Alsouqi A, Huang S, Xu M, Ferguson JF, Su YR, Niswender KD, Ikizler TA, Wang TJ. Acute effects of insulin on circulating natriuretic peptide levels in humans. PLoS ONE. 2018; 13(5): e0196869. PMID: 29758041, PMCID: PMC5951576, PII: PONE-D-17-42749, DOI: 10.1371/journal.pone.0196869, ISSN: 1932-6203.

Zhang H, Hinkle CC, O'Neill SM, Shi J, Caughey J, Lynch E, Lynch G, Gerelus M, Tsai ASD, Shah R, Ferguson JF, Ahima RS, Reilly MP. Synergistic modulation of inflammatory but not metabolic effects of high-fat feeding by CCR2 and CX3CR1. Obesity (Silver Spring) [print-electronic]. 2017 Jun 6/26/2017; PMID: 28650582, DOI: 10.1002/oby.21900, ISSN: 1930-739X.

Saleheen D, Zhao W, Young R, Nelson CP, Ho W, Ferguson JF, Rasheed A, Ou K, Nurnberg ST, Bauer RC, Goel A, Do R, Stewart AFR, Hartiala J, Zhang W, Thorleifsson G, Strawbridge RJ, Sinisalo J, Kanoni S, Sedaghat S, Marouli E, Kristiansson K, Hua Zhao J, Scott R, Gauguier D, Shah SH, Smith AV, van Zuydam N, Cox AJ, Willenborg C, Kessler T, Zeng L, Province MA, Ganna A, Lind L, Pedersen NL, White CC, Joensuu A, Edi Kleber M, Hall AS, März W, Salomaa V, O'Donnell C, Ingelsson E, Feitosa MF, Erdmann J, Bowden DW, Palmer CNA, Gudnason V, Faire U, Zalloua P, Wareham N, Thompson JR, Kuulasmaa K, Dedoussis G, Perola M, Dehghan A, Chambers JC, Kooner J, Allayee H, Deloukas P, McPherson R, Stefansson K, Schunkert H, Kathiresan S, Farrall M, Marcel Frossard P, Rader DJ, Samani NJ, Reilly MP. Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation [print-electronic]. 2017 Jun 6/13/2017; 135(24): 2336-53. PMID: 28461624, PII: CIRCULATIONAHA.116.022069, DOI: 10.1161/CIRCULATIONAHA.116.022069, ISSN: 1524-4539.

Xue C, Zhang X, Zhang H, Ferguson JF, Wang Y, Hinkle CC, Li M, Reilly MP. De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14(+) monocytes and in adipose tissue. Physiol. Genomics [print-electronic]. 2017 Jun 6/1/2017; 49(6): 287-305. PMID: 28389524, PMCID: PMC5495909, PII: physiolgenomics.00001.2017, DOI: 10.1152/physiolgenomics.00001.2017, ISSN: 1531-2267.

Shah RD, Xue C, Zhang H, Tuteja S, Li M, Reilly MP, Ferguson JF. Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells. PLoS ONE. 2017; 12(1): e0169614. PMID: 28125622, PMCID: PMC5268473, PII: PONE-D-16-19159, DOI: 10.1371/journal.pone.0169614, ISSN: 1932-6203.

, Young DR, Hivert MF, Alhassan S, Camhi SM, Ferguson JF, Katzmarzyk PT, Lewis CE, Owen N, Perry CK, Siddique J, Yong CM, . Sedentary Behavior and Cardiovascular Morbidity and Mortality: A Science Advisory From the American Heart Association. Circulation [print-electronic]. 2016 Sep 9/27/2016; 134(13): e262-79. PMID: 27528691, PII: CIR.0000000000000440, DOI: 10.1161/CIR.0000000000000440, ISSN: 1524-4539.

Ferguson JF, Allayee H, Gerszten RE, Ideraabdullah F, Kris-Etherton PM, Ordovás JM, Rimm EB, Wang TJ, Bennett BJ, . Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association. Circ Cardiovasc Genet [print-electronic]. 2016 Jun; 9(3): 291-313. PMID: 27095829, PII: HCG.0000000000000030, DOI: 10.1161/HCG.0000000000000030, ISSN: 1942-3268.

Ferguson JF, Xue C, Hu Y, Li M, Reilly MP. Adipose tissue RNASeq reveals novel gene-nutrient interactions following n-3 PUFA supplementation and evoked inflammation in humans. J. Nutr. Biochem [print-electronic]. 2016 Apr; 30: 126-32. PMID: 27012629, PMCID: PMC4808243, PII: S0955-2863(16)00008-5, DOI: 10.1016/j.jnutbio.2015.12.010, ISSN: 1873-4847.

Ferguson JF, Wang TJ. Branched-Chain Amino Acids and Cardiovascular Disease: Does Diet Matter? [editorial]. Clin. Chem [print-electronic]. 2016 Apr; 62(4): 545-7. PMID: 26883074, PII: clinchem.2016.254318, DOI: 10.1373/clinchem.2016.254318, ISSN: 1530-8561.

Skarke C, Alamuddin N, Lawson JA, Li X, Ferguson JF, Reilly MP, FitzGerald GA. Bioactive products formed in humans from fish oils. J. Lipid Res [print-electronic]. 2015 Sep; 56(9): 1808-20. PMID: 26180051, PMCID: PMC4548785, PII: jlr.M060392, DOI: 10.1194/jlr.M060392, ISSN: 1539-7262.

Ferguson JF, Shah RY, Shah R, Mehta NN, Rickels MR, Reilly MP. Activation of innate immunity modulates insulin sensitivity, glucose effectiveness and pancreatic ß-cell function in both African ancestry and European ancestry healthy humans. Metab. Clin. Exp [print-electronic]. 2015 Apr; 64(4): 513-20. PMID: 25579865, PMCID: PMC4346476, PII: S0026-0495(14)00395-3, DOI: 10.1016/j.metabol.2014.12.007, ISSN: 1532-8600.

Ferguson JF, Shah RY, Shah R, Mehta NN, Rickels MR, Reilly MP. Activation of innate immunity modulates insulin sensitivity, glucose effectiveness and pancreatic ß-cell function in both African ancestry and European ancestry healthy humans. Metab. Clin. Exp [print-electronic]. 2015 Apr; 64(4): 513-20. PMID: 25579865, PMCID: PMC4346476, PII: S0026-0495(14)00395-3, DOI: 10.1016/j.metabol.2014.12.007, ISSN: 1532-8600.

Ferguson JF, Meyer NJ, Qu L, Xue C, Liu Y, DerOhannessian SL, Rushefski M, Paschos GK, Tang S, Schadt EE, Li M, Christie JD, Reilly MP. Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans. Hum. Mol. Genet [print-electronic]. 2015 Mar 3/15/2015; 24(6): 1801-12. PMID: 25416278, PMCID: PMC4351381, PII: ddu589, DOI: 10.1093/hmg/ddu589, ISSN: 1460-2083.

Ferguson JF, Meyer NJ, Qu L, Xue C, Liu Y, DerOhannessian SL, Rushefski M, Paschos GK, Tang S, Schadt EE, Li M, Christie JD, Reilly MP. Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans. Hum. Mol. Genet [print-electronic]. 2015 Mar 3/15/2015; 24(6): 1801-12. PMID: 25416278, PMCID: PMC4351381, PII: ddu589, DOI: 10.1093/hmg/ddu589, ISSN: 1460-2083.

Patel PN, Shah RY, Ferguson JF, Reilly MP. Human experimental endotoxemia in modeling the pathophysiology, genomics, and therapeutics of innate immunity in complex cardiometabolic diseases. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2015 Mar; 35(3): 525-34. PMID: 25550206, PMCID: PMC4344396, PII: ATVBAHA.114.304455, DOI: 10.1161/ATVBAHA.114.304455, ISSN: 1524-4636.

Walley KR, Thain KR, Russell JA, Reilly MP, Meyer NJ, Ferguson JF, Christie JD, Nakada TA, Fjell CD, Thair SA, Cirstea MS, Boyd JH. PCSK9 is a critical regulator of the innate immune response and septic shock outcome. Sci Transl Med. 2014 Oct 10/15/2014; 6(258): 258ra143. PMID: 25320235, PMCID: PMC4342147, PII: 6/258/258ra143, DOI: 10.1126/scitranslmed.3008782, ISSN: 1946-6242.

Prenner SB, Mulvey CK, Ferguson JF, Rickels MR, Bhatt AB, Reilly MP. Very low density lipoprotein cholesterol associates with coronary artery calcification in type 2 diabetes beyond circulating levels of triglycerides. Atherosclerosis [print-electronic]. 2014 Oct; 236(2): 244-50. PMID: 25105581, PMCID: PMC4209900, PII: S0021-9150(14)01284-2, DOI: 10.1016/j.atherosclerosis.2014.07.008, ISSN: 1879-1484.

Meyer NJ, Ferguson JF, Feng R, Wang F, Patel PN, Li M, Xue C, Qu L, Liu Y, Boyd JH, Russell JA, Christie JD, Walley KR, Reilly MP. A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock. Am. J. Respir. Crit. Care Med. 2014 Sep 9/15/2014; 190(6): 656-64. PMID: 25089931, PMCID: PMC4214110, DOI: 10.1164/rccm.201403-0586OC, ISSN: 1535-4970.

Ferguson JF, Ryan MF, Gibney ER, Brennan L, Roche HM, Reilly MP. Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers. Nutr Metab Cardiovasc Dis [print-electronic]. 2014 Sep; 24(9): 996-1003. PMID: 24875672, PMCID: PMC4130742, PII: S0939-4753(14)00130-6, DOI: 10.1016/j.numecd.2014.03.010, ISSN: 1590-3729.

Rickels MR, Kong SM, Fuller C, Dalton-Bakes C, Ferguson JF, Reilly MP, Teff KL, Naji A. Insulin sensitivity index in type 1 diabetes and following human islet transplantation: comparison of the minimal model to euglycemic clamp measures. Am. J. Physiol. Endocrinol. Metab [print-electronic]. 2014 May 5/15/2014; 306(10): E1217-24. PMID: 24691031, PMCID: PMC4025062, PII: ajpendo.00667.2013, DOI: 10.1152/ajpendo.00667.2013, ISSN: 1522-1555.

Liu Y, Ferguson JF, Xue C, Ballantyne RL, Silverman IM, Gosai SJ, Serfecz J, Morley MP, Gregory BD, Li M, Reilly MP. Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2014 Apr; 34(4): 902-12. PMID: 24504737, PMCID: PMC3966947, PII: ATVBAHA.113.303123, DOI: 10.1161/ATVBAHA.113.303123, ISSN: 1524-4636.

Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert KJ, Song WL, Reilly MP. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol Nutr Food Res [print-electronic]. 2014 Mar; 58(3): 601-13. PMID: 24190860, PMCID: PMC3947472, DOI: 10.1002/mnfr.201300368, ISSN: 1613-4133.

Hu Y, Liu Y, Mao X, Jia C, Ferguson JF, Xue C, Reilly MP, Li H, Li M. PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution. Nucleic Acids Res [print-electronic]. 2014 Feb; 42(3): e20. PMID: 24362841, PMCID: PMC3919567, PII: gkt1304, DOI: 10.1093/nar/gkt1304, ISSN: 1362-4962.

Walsh MC, McLoughlin GA, Roche HM, Ferguson JF, Drevon CA, Saris WH, Lovegrove JA, Risérus U, López-Miranda J, Defoort C, Kiec-Wilk B, Brennan L, Gibney MJ. Impact of geographical region on urinary metabolomic and plasma fatty acid profiles in subjects with the metabolic syndrome across Europe: the LIPGENE study. Br. J. Nutr [print-electronic]. 2014 Feb; 111(3): 424-31. PMID: 24047691, PII: S0007114513002602, DOI: 10.1017/S0007114513002602, ISSN: 1475-2662.

Mulvey CK, McNeill AM, Girman CJ, Churchill TW, Terembula K, Ferguson JF, Shah R, Mehta NN, Qasim AN, Rickels MR, Reilly MP. Differential associations of oral glucose tolerance test-derived measures of insulin sensitivity and pancreatic ß-cell function with coronary artery calcification and microalbuminuria in type 2 diabetes. Diabetes Care [print-electronic]. 2014; 37(1): 124-33. PMID: 23949560, PMCID: PMC3867998, PII: dc12-1880, DOI: 10.2337/dc12-1880, ISSN: 1935-5548.

Rickels MR, Kong SM, Fuller C, Dalton-Bakes C, Ferguson JF, Reilly MP, Teff KL, Naji A. Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes. J. Clin. Endocrinol. Metab [print-electronic]. 2013 Nov; 98(11): E1780-5. PMID: 24085506, PMCID: PMC3816271, PII: jc.2013-1764, DOI: 10.1210/jc.2013-1764, ISSN: 1945-7197.

Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN, Shen H, Mitchell BD, O'Connell JR, Shuldiner AR, Ho WK, Young R, Rasheed A, Danesh J, He J, Kusek JW, Ojo AO, Flack J, Go AS, Gadegbeku CA, Wright JT, Saleheen D, Feldman HI, Rader DJ, Foulkes AS, Reilly MP, . Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort). J. Am. Coll. Cardiol [print-electronic]. 2013 Aug 8/27/2013; 62(9): 789-98. PMID: 23727086, PMCID: PMC3953823, PII: S0735-1097(13)02075-5, DOI: 10.1016/j.jacc.2013.01.103, ISSN: 1558-3597.

Ferguson JF. Meat-loving microbes: do steak-eating bacteria promote atherosclerosis?. Circ Cardiovasc Genet. 2013 Jun; 6(3): 308-9. PMID: 23778590, PII: CIRCGENETICS.113.000213, DOI: 10.1161/CIRCGENETICS.113.000213, ISSN: 1942-3268.

Wojczynski MK, Li M, Bielak LF, Kerr KF, Reiner AP, Wong ND, Yanek LR, Qu L, White CC, Lange LA, Ferguson JF, He J, Young T, Mosley TH, Smith JA, Kral BG, Guo X, Wong Q, Ganesh SK, Heckbert SR, Griswold ME, O'Leary DH, Budoff M, Carr JJ, Taylor HA, Bluemke DA, Demissie S, Hwang SJ, Paltoo DN, Polak JF, Psaty BM, Becker DM, Province MA, Post WS, O'Donnell CJ, Wilson JG, Harris TB, Kavousi M, Cupples LA, Rotter JI, Fornage M, Becker LC, Peyser PA, Borecki IB, Reilly MP. Genetics of coronary artery calcification among African Americans, a meta-analysis. BMC Med. Genet. 2013; 14: 75. PMID: 23870195, PMCID: PMC3733595, PII: 1471-2350-14-75, DOI: 10.1186/1471-2350-14-75, ISSN: 1471-2350.

Liu Y, Ferguson JF, Xue C, Silverman IM, Gregory B, Reilly MP, Li M. Evaluating the impact of sequencing depth on transcriptome profiling in human adipose. PLoS ONE [electronic-print]. 2013; 8(6): e66883. PMID: 23826166, PMCID: PMC3691247, PII: PONE-D-13-06298, DOI: 10.1371/journal.pone.0066883, ISSN: 1932-6203.

Ferguson JF, Patel PN, Shah RY, Mulvey CK, Gadi R, Nijjar PS, Usman HM, Mehta NN, Shah R, Master SR, Propert KJ, Reilly MP. Race and gender variation in response to evoked inflammation. J Transl Med. 2013; 11: 63. PMID: 23497455, PMCID: PMC3636014, PII: 1479-5876-11-63, DOI: 10.1186/1479-5876-11-63, ISSN: 1479-5876.

Foulkes AS, Matthews GJ, Das U, Ferguson JF, Lin R, Reilly MP. Mixed modeling of meta-analysis P-values (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol. PLoS ONE [print-electronic]. 2013; 8(2): e54812. PMID: 23405096, PMCID: PMC3566142, PII: PONE-D-12-18267, DOI: 10.1371/journal.pone.0054812, ISSN: 1932-6203.

Ferguson JF. Increasing power: multivariate analysis of metabolic networks reveals novel atherosclerosis loci. Circ Cardiovasc Genet. 2012 Oct 10/1/2012; 5(5): 595-6. PMID: 23074341, PII: 5/5/595, DOI: 10.1161/CIRCGENETICS.112.964882, ISSN: 1942-3268.

Oliver E, McGillicuddy FC, Harford KA, Reynolds CM, Phillips CM, Ferguson JF, Roche HM. Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. J. Nutr. Biochem [print-electronic]. 2012 Sep; 23(9): 1192-200. PMID: 22137266, PII: S0955-2863(11)00210-5, DOI: 10.1016/j.jnutbio.2011.06.014, ISSN: 1873-4847.

Mulvey CK, Ferguson JF, Tabita-Martinez J, Kong S, Shah RY, Patel PN, Master SR, Usman MH, Propert KJ, Shah R, Mehta NN, Reilly MP. Peroxisome Proliferator-Activated Receptor-a Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia. J Am Heart Assoc [print-electronic]. 2012 Aug; 1(4): e002923. PMID: 23130172, PMCID: PMC3487364, PII: jah362, DOI: 10.1161/JAHA.112.002923, ISSN: 2047-9980.

Ferguson JF. Omics gets personal: integrative profiling of health and disease. Circ Cardiovasc Genet. 2012 Jun; 5(3): 381-2. PMID: 22715285, PII: 5/3/381, DOI: 10.1161/CIRCGENETICS.112.963801, ISSN: 1942-3268.

Wassel CL, Lamina C, Nambi V, Coassin S, Mukamal KJ, Ganesh SK, Jacobs DR, Franceschini N, Papanicolaou GJ, Gibson Q, Yanek LR, van der Harst P, Ferguson JF, Crawford DC, Waite LL, Allison MA, Criqui MH, McDermott MM, Mehra R, Cupples LA, Hwang SJ, Redline S, Kaplan RC, Heiss G, Rotter JI, Boerwinkle E, Taylor HA, Eraso LH, Haun M, Li M, Meisinger C, O'Connell JR, Shuldiner AR, Tybjærg-Hansen A, Frikke-Schmidt R, Kollerits B, Rantner B, Dieplinger B, Stadler M, Mueller T, Haltmayer M, Klein-Weigel P, Summerer M, Wichmann HE, Asselbergs FW, Navis G, Mateo Leach I, Brown-Gentry K, Goodloe R, Assimes TL, Becker DM, Cooke JP, Absher DM, Olin JW, Mitchell BD, Reilly MP, Mohler ER, North KE, Reiner AP, Kronenberg F, Murabito JM. Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. Atherosclerosis [print-electronic]. 2012 May; 222(1): 138-47. PMID: 22361517, PMCID: PMC3596171, PII: S0021-9150(12)00072-X, DOI: 10.1016/j.atherosclerosis.2012.01.039, ISSN: 1879-1484.

Davies RW, Wells GA, Stewart AF, Erdmann J, Shah SH, Ferguson JF, Hall AS, Anand SS, Burnett MS, Epstein SE, Dandona S, Chen L, Nahrstaedt J, Loley C, König IR, Kraus WE, Granger CB, Engert JC, Hengstenberg C, Wichmann HE, Schreiber S, Tang WH, Ellis SG, Rader DJ, Hazen SL, Reilly MP, Samani NJ, Schunkert H, Roberts R, McPherson R. A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. Circ Cardiovasc Genet [print-electronic]. 2012 Apr 4/1/2012; 5(2): 217-25. PMID: 22319020, PMCID: PMC3335297, PII: CIRCGENETICS.111.961243, DOI: 10.1161/CIRCGENETICS.111.961243, ISSN: 1942-3268.

Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM, , , Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am. J. Hum. Genet [print-electronic]. 2012 Mar 3/9/2012; 90(3): 410-25. PMID: 22325160, PMCID: PMC3309185, PII: S0002-9297(12)00031-6, DOI: 10.1016/j.ajhg.2011.12.022, ISSN: 1537-6605.

Ferguson JF, Hinkle CC, Mehta NN, Bagheri R, Derohannessian SL, Shah R, Mucksavage MI, Bradfield JP, Hakonarson H, Wang X, Master SR, Rader DJ, Li M, Reilly MP. Translational studies of lipoprotein-associated phospholipase A2 in inflammation and atherosclerosis. J. Am. Coll. Cardiol. 2012 Feb 2/21/2012; 59(8): 764-72. PMID: 22340269, PMCID: PMC3285416, PII: S0735-1097(11)05099-6, DOI: 10.1016/j.jacc.2011.11.019, ISSN: 1558-3597.

Barth AS, Ferguson JF, Musunuru K. Top advances in functional genomics and translational biology for 2011. Circ Cardiovasc Genet. 2012 Feb 2/1/2012; 5(1): 143-5. PMID: 22337927, PII: 5/1/143, DOI: 10.1161/CIRCGENETICS.111.962621, ISSN: 1942-3268.

Mehta NN, Heffron SP, Patel PN, Ferguson J, Shah RD, Hinkle CC, Krishnamoorthy P, Shah R, Tabita-Martinez J, Terembula K, Master SR, Rickels MR, Reilly MP. A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial. J Transl Med. 2012; 10: 124. PMID: 22709547, PMCID: PMC3477112, PII: 1479-5876-10-124, DOI: 10.1186/1479-5876-10-124, ISSN: 1479-5876.

Garcia-Rios A, Delgado-Lista J, Perez-Martinez P, Phillips CM, Ferguson JF, Gjelstad IM, Williams CM, Karlström B, Kiec-Wilk B, Blaak EE, Lairon D, Planells R, Malczewska-Malec M, Defoort C, Riserus U, Saris WH, Lovegrove JA, Drevon CA, Roche HM, Lopez-Miranda J. Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism. Atherosclerosis [print-electronic]. 2011 Oct; 218(2): 416-22. PMID: 21840003, PII: S0021-9150(11)00713-1, DOI: 10.1016/j.atherosclerosis.2011.07.092, ISSN: 1879-1484.

. Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet [print-electronic]. 2011 Sep; 7(9): e1002260. PMID: 21966275, PMCID: PMC3178591, PII: PGENETICS-D-11-00460, DOI: 10.1371/journal.pgen.1002260, ISSN: 1553-7404.

Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, Ferguson JF, Gulseth HL, Williams CM, Karlström B, Kiec-Wilk B, Blaak EE, Helal O, Malczewska-Malec M, Defoort C, Risérus U, Saris WH, Lovegrove JA, Drevon CA, Roche HM, Lopez-Miranda J. Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome. Am. J. Clin. Nutr [print-electronic]. 2011 May; 93(5): 1136-41. PMID: 21389182, PII: ajcn.110.010512, DOI: 10.3945/ajcn.110.010512, ISSN: 1938-3207.

Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS, Reilly MP. Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes. 2011 May; 60(5): 1512-8. PMID: 21525510, PMCID: PMC3292325, PII: 60/5/1512, DOI: 10.2337/db10-0956, ISSN: 1939-327X.

Mehta NN, Li M, William D, Khera AV, DerOhannessian S, Qu L, Ferguson JF, McLaughlin C, Shaikh LH, Shah R, Patel PN, Bradfield JP, He J, Stylianou IM, Hakonarson H, Rader DJ, Reilly MP. The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels. Eur. Heart J [print-electronic]. 2011 Apr; 32(8): 963-71. PMID: 21415067, PMCID: PMC3076669, PII: ehr091, DOI: 10.1093/eurheartj/ehr091, ISSN: 1522-9645.

Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, , , Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet [print-electronic]. 2011 Jan 1/29/2011; 377(9763): 383-92. PMID: 21239051, PMCID: PMC3297116, PII: S0140-6736(10)61996-4, DOI: 10.1016/S0140-6736(10)61996-4, ISSN: 1474-547X.

Eliot M, Ferguson J, Reilly MP, Foulkes AS. Ridge regression for longitudinal biomarker data. Int J Biostat [print-electronic]. 2011; 7(1): Article 37. PMID: 22049265, PMCID: PMC3202941, DOI: 10.2202/1557-4679.1353, ISSN: 1557-4679.

Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, Liu J, Post W, O'Connell JR, Hixson JE, Kardia SL, Sun YV, Jhun MA, Wang X, Mehta NN, Li M, Koller DL, Hakonarson H, Keating BJ, Rader DJ, Shuldiner AR, Peyser PA, Reilly MP, Mitchell BD. Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2010 Dec; 30(12): 2648-54. PMID: 20847308, PMCID: PMC2988112, PII: ATVBAHA.110.211805, DOI: 10.1161/ATVBAHA.110.211805, ISSN: 1524-4636.

Ferguson JF, Phillips CM, McMonagle J, Pérez-Martínez P, Shaw DI, Lovegrove JA, Helal O, Defoort C, Gjelstad IM, Drevon CA, Blaak EE, Saris WH, Leszczynska-Golabek I, Kiec-Wilk B, Risérus U, Karlström B, Lopez-Miranda J, Roche HM. NOS3 gene polymorphisms are associated with risk markers of cardiovascular disease, and interact with omega-3 polyunsaturated fatty acids. Atherosclerosis [print-electronic]. 2010 Aug; 211(2): 539-44. PMID: 20409549, PII: S0021-9150(10)00243-1, DOI: 10.1016/j.atherosclerosis.2010.03.027, ISSN: 1879-1484.

Ferguson JF, Phillips CM, Tierney AC, Pérez-Martínez P, Defoort C, Helal O, Lairon D, Planells R, Shaw DI, Lovegrove JA, Gjelstad IM, Drevon CA, Blaak EE, Saris WH, Leszczynska-Golabek I, Kiec-Wilk B, Risérus U, Karlström B, Miranda JL, Roche HM. Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance. Am. J. Clin. Nutr [print-electronic]. 2010 Mar; 91(3): 794-801. PMID: 20032495, PII: ajcn.2009.28255, DOI: 10.3945/ajcn.2009.28255, ISSN: 1938-3207.

Phillips CM, Goumidi L, Bertrais S, Ferguson JF, Field MR, Kelly ED, Mehegan J, Peloso GM, Cupples LA, Shen J, Ordovas JM, McManus R, Hercberg S, Portugal H, Lairon D, Planells R, Roche HM. Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. J. Clin. Endocrinol. Metab [print-electronic]. 2010 Mar; 95(3): 1386-94. PMID: 20080841, PII: jc.2009-1081, DOI: 10.1210/jc.2009-1081, ISSN: 1945-7197.

Phillips CM, Goumidi L, Bertrais S, Ferguson JF, Field MR, Kelly ED, Peloso GM, Cupples LA, Shen J, Ordovas JM, McManus R, Hercberg S, Portugal H, Lairon D, Planells R, Roche HM. Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome. Am. J. Clin. Nutr [print-electronic]. 2009 Dec; 90(6): 1665-73. PMID: 19828715, PII: ajcn.2009.28101, DOI: 10.3945/ajcn.2009.28101, ISSN: 1938-3207.