Faculty Appointments
Associate Professor of Anesthesiology
Associate Professor of Pathology, Microbiology and Immunology
Education
Ph.D., University of Texas Medical Branch, Galveston, TexasB.S., Eastern Kentucky University, Richmond, Kentucky
Office Address
1161 21st Ave S
Nashville, TN 37232-2520
Nashville, TN 37232-2520
Research Description
The Bohannon Laboratory studies innate immune responses to infection in immunocompromised hosts. Specifically, our research is aimed at investigating immunomodulatory therapies for the prevention of infection and sepsis following a severe burn injury. Infection is the leading cause of death and prolonged hospitalization in severely burned patients that survive the acute phase of injury. Loss of the skin barrier, impaired innate immunity and the prevalence of antibiotic resistant bacteria increase the susceptibility of burn patients to serious infection, leading to a great need for immunomodulation strategies aimed at priming the host response in these patients. Little is known regarding how leukocyte function is altered by burn injury. A major objective our the Bohannon Lab is to study the functional and metabolic consequences on innate immune cells following traumatic burn injury and subsequent infection. Another objective is to assess whether immunomodulation can reverse or enhance innate immune function and restore immune competence after burn. Priming with Toll-like receptor 4 agonists have been shown to augment macrophage and neutrophil antimicrobial responses and enhance resistance against infection after severe burn injury in mice through the induction of trained immunity. However, the role of the classical MyD88- and TRIF-dependent TLR signaling cascades in mediating this protection, are not fully understood. Our studies support a primary role for MyD88-signaling in mediating antimicrobial responses, potentially through augmentation of leukocyte metabolism, but the cellular and molecular mechanisms involved are unclear. The Bohannon lab utilizes multiple post-burn murine infection models, including a Pseudomonas aeruginosa burn wound infection as well as Staphylococcal aureus and Candida albicans systemic infections, to assess the effect of various TLR agonists on mediating protection against infection. In addition, leukocyte samples from human burn patients in the Vanderbilt Burn Unit are being assessed to evaluate immune cell dysfunction and how stimulation with immunomodulating agonists affect leukocyte function. The information gained from this project will advance current knowledge by elucidating the role played by the two primary TLR signaling pathways in mediating resistance to infection in burn patients, and by investigating the potential of harnessing these pathways for therapeutic benefit in these patients. These studies will also fill important gaps in knowledge by improving our understanding of how TLR agonists modulate innate immune responses.
Research Keywords
immunomodulation, toll-like receptor, agonist, endotoxin, burn injury, sepsis, burn wound infection
Publications
Bolden M, Davis XD, Kapadia M, Nguyen E, Sherwood ER, Bohannon JK, Caslin HL. WEIGHT LOSS-INDUCED ADIPOSE MACROPHAGE MEMORY CORRESPONDS WITH LOWER ADIPOSE BACTERIAL BURDEN IN MURINE SYSTEMIC STAPHYLOCOCCUS AUREUS INFECTION. Shock [print-electronic]. 2025 Jun 6/1/2025; 63(6): 919-28. PMID: 40101956, PII: 00024382-202506000-00016, DOI: 10.1097/SHK.0000000000002575, ISSN: 1540-0514.
Hao D, McBride MA, Bohannon JK, Hernandez A, Klein B, Williams DL, Sherwood ER. Metabolic adaptations driving innate immune memory: mechanisms and therapeutic implications. J Leukoc Biol. 2025 May 5/7/2025; 117(5): PMID: 40138361, PMCID: PMC12094284, PII: 8095364, DOI: 10.1093/jleuko/qiaf037, ISSN: 1938-3673.
Hao D, Caja KR, McBride MA, Owen AM, Bohannon JK, Hernandez A, Ali S, Dalal S, Williams DL, Sherwood ER. Trained immunity enhances host resistance to infection in aged mice. J Leukoc Biol. 2025 Apr 4/23/2025; 117(4): PMID: 39722231, PMCID: PMC12022634, PII: 7932571, DOI: 10.1093/jleuko/qiae259, ISSN: 1938-3673.
McBride MA, Caja KR, Patil TK, Owen AM, Luan L, Bohannon JK, Hernandez A, Stothers CL, Trenary IA, Rahim M, Young JD, Calcutt MW, Stephens VR, Davis X, Oliver MA, Hao D, Si C, McRae M, Nguyen KK, Davis NS, Wang J, Patil NK, Sherwood ER. Immunoresponsive gene 1 facilitates TLR4 agonist-induced augmentation of innate antimicrobial immunity. J Leukoc Biol. 2025 Feb 2/13/2025; 117(2): PMID: 39351765, PMCID: PMC11879002, PII: 7798214, DOI: 10.1093/jleuko/qiae198, ISSN: 1938-3673.
Nabukhotna K, Kordus SL, Shupe JA, Cano Rodríguez R, Smith A, Bohannon JK, Washington MK, Lacy DB. Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection. PLoS Pathog. 2024 Sep; 20(9): e1012568. PMID: 39298531, PMCID: PMC11444381, PII: PPATHOGENS-D-24-01481, DOI: 10.1371/journal.ppat.1012568, ISSN: 1553-7374.
Oliver MA, Davis XD, Bohannon JK. TGFß macrophage reprogramming: a new dimension of macrophage plasticity. J Leukoc Biol. 2024 Feb 2/23/2024; 115(3): 411-4. PMID: 38197509, PMCID: PMC11423798, PII: 7513893, DOI: 10.1093/jleuko/qiae001, ISSN: 1938-3673.
McBride MA, Stothers CL, Fensterheim BA, Caja KR, Owen AM, Hernandez A, Bohannon JK, Patil NK, Ali S, Dalal S, Rahim M, Trenary IA, Young JD, Williams DL, Sherwood ER. Bacteria- and fungus-derived PAMPs induce innate immune memory via similar functional, metabolic, and transcriptional adaptations. J Leukoc Biol. 2024 Jan 1/19/2024; 115(2): 358-73. PMID: 37793181, PMCID: PMC10872320, PII: 7289224, DOI: 10.1093/jleuko/qiad120, ISSN: 1938-3673.
Schaaf KR, Landstreet SR, Pugazenthi S, Qian EY, Putz ND, Siderova T, Owen AM, Bohannon JK, Ware LB, Bastarache JA, Shaver CM. Cell-free hemoglobin triggers macrophage cytokine production via TLR4 and MyD88. Am J Physiol Lung Cell Mol Physiol [print-electronic]. 2024 Jan 1/1/2024; 326(1): L29-L38-L38. PMID: 37991487, PMCID: PMC11279742, DOI: 10.1152/ajplung.00123.2023, ISSN: 1522-1504.
Hernandez A, Patil NK, Brewer M, Delgado R, Himmel L, Lopez LN, Bohannon JK, Owen AM, Sherwood ER, de Caestecker MP. Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol [print-electronic]. 2023 May 5/1/2023; 324(5): F472-F482-F482. PMID: 36995924, PMCID: PMC10151043, DOI: 10.1152/ajprenal.00248.2022, ISSN: 1522-1466.
Hernandez A, Zhou J, Bohannon JK, McBride MA, Gibson-Corley KN, Patil NK, Owen AM, Burelbach KR, Sherwood ER. INTRAPULMONARY TREATMENT WITH A NOVEL TLR4 AGONIST CONFERS PROTECTION AGAINST KLEBSIELLA PNEUMONIA. Shock [print-electronic]. 2022 Oct 10/1/2022; 58(4): 295-303. PMID: 36018281, PII: 00024382-202210000-00007, DOI: 10.1097/SHK.0000000000001977, ISSN: 1540-0514.
Hernandez A, Zhou J, Bohannon JK, McBride MA, Gibson-Corley KN, Patil NK, Owen AM, Burelbach KR, Sherwood ER. INTRAPULMONARY TREATMENT WITH A NOVEL TLR4 AGONIST CONFERS PROTECTION AGAINST KLEBSIELLA PNEUMONIA. Shock [print-electronic]. 2022 Oct 10/1/2022; 58(4): 295-303. PMID: 36018281, PMCID: PMC9647733, PII: 00024382-202210000-00007, DOI: 10.1097/SHK.0000000000001977, ISSN: 1540-0514.
Burmeister DM, Supp DM, Clark RA, Tredget EE, Powell HM, Enkhbaatar P, Bohannon JK, Cancio LC, Hill DM, Nygaard RM. Advantages and Disadvantages of Using Small and Large Animals in Burn Research: Proceedings of the 2021 Research Special Interest Group. J Burn Care Res. 2022 Sep 9/1/2022; 43(5): 1032-41. PMID: 35778269, PII: 6626055, DOI: 10.1093/jbcr/irac091, ISSN: 1559-0488.
Burmeister DM, Supp DM, Clark RA, Tredget EE, Powell HM, Enkhbaatar P, Bohannon JK, Cancio LC, Hill DM, Nygaard RM. Advantages and Disadvantages of Using Small and Large Animals in Burn Research: Proceedings of the 2021 Research Special Interest Group. J Burn Care Res. 2022 Sep 9/1/2022; 43(5): 1032-41. PMID: 35778269, PII: 6626055, DOI: 10.1093/jbcr/irac091, ISSN: 1559-0488.
Sherwood ER, Burelbach KR, McBride MA, Stothers CL, Owen AM, Hernandez A, Patil NK, Williams DL, Bohannon JK. Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 Feb 2/15/2022; 208(4): 785-92. PMID: 35115374, PMCID: PMC8982914, PII: jimmunol.2101058, DOI: 10.4049/jimmunol.2101058, ISSN: 1550-6606.
Sherwood ER, Burelbach KR, McBride MA, Stothers CL, Owen AM, Hernandez A, Patil NK, Williams DL, Bohannon JK. Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 Feb 2/15/2022; 208(4): 785-92. PMID: 35115374, PMCID: PMC8982914, PII: jimmunol.2101058, DOI: 10.4049/jimmunol.2101058, ISSN: 1550-6606.
Patil NK, Bohannon JK, Vachharajani V, McCall CE. Editorial: The Roles of Mitochondria in Immunity [editorial]. Front Immunol. 2022; 13: 914639. PMID: 35651600, PMCID: PMC9149419, DOI: 10.3389/fimmu.2022.914639, ISSN: 1664-3224.
Patil NK, Bohannon JK, Vachharajani V, McCall CE. Editorial: The Roles of Mitochondria in Immunity [editorial]. Front Immunol. 2022; 13: 914639. PMID: 35651600, PMCID: PMC9149419, DOI: 10.3389/fimmu.2022.914639, ISSN: 1664-3224.
Owen AM, Luan L, Burelbach KR, McBride MA, Stothers CL, Boykin OA, Sivanesam K, Schaedel JF, Patil TK, Wang J, Hernandez A, Patil NK, Sherwood ER, Bohannon JK. MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages. Front Immunol. 2022; 13: 1044662. PMID: 36439136, PMCID: PMC9692127, DOI: 10.3389/fimmu.2022.1044662, ISSN: 1664-3224.
Stothers CL, Burelbach KR, Owen AM, Patil NK, McBride MA, Bohannon JK, Luan L, Hernandez A, Patil TK, Williams DL, Sherwood ER. ß-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages. J Immunol [print-electronic]. 2021 Dec 12/1/2021; 207(11): 2785-98. PMID: 34740960, PMCID: PMC8612974, PII: jimmunol.2100107, DOI: 10.4049/jimmunol.2100107, ISSN: 1550-6606.
Stothers CL, Burelbach KR, Owen AM, Patil NK, McBride MA, Bohannon JK, Luan L, Hernandez A, Patil TK, Williams DL, Sherwood ER. ß-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages. J Immunol [print-electronic]. 2021 Dec 12/1/2021; 207(11): 2785-98. PMID: 34740960, PMCID: PMC8612974, PII: jimmunol.2100107, DOI: 10.4049/jimmunol.2100107, ISSN: 1550-6606.
Bohannon JK, Sherwood ER. What's New in Shock, April 2021?. Shock. 2021 Apr 4/1/2021; 55(4): 419-22. PMID: 33730006, PII: 00024382-202104000-00001, DOI: 10.1097/SHK.0000000000001760, ISSN: 1540-0514.
Bohannon JK, Sherwood ER. What's New in Shock, April 2021?. Shock. 2021 Apr 4/1/2021; 55(4): 419-22. PMID: 33730006, PII: 00024382-202104000-00001, DOI: 10.1097/SHK.0000000000001760, ISSN: 1540-0514.
Hernandez A, Patil NK, Bohannon JK. A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection. Methods Mol Biol. 2021; 2321: 111-20. PMID: 34048011, PMCID: PMC9057493, DOI: 10.1007/978-1-0716-1488-4_10, ISSN: 1940-6029.
Hernandez A, Patil NK, Bohannon JK. A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection. Methods Mol Biol. 2021; 2321: 111-20. PMID: 34048011, PMCID: PMC9057493, DOI: 10.1007/978-1-0716-1488-4_10, ISSN: 1940-6029.
Fukuda S, Ihara K, Bohannon JK, Hernandez A, Patil NK, Luan L, Stothers C, Stark R, Prough DS, Herndon DN, Sherwood ER, Enkhbaatar P. Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep. Shock. 2020 Mar; 53(3): 307-16. PMID: 31045990, PMCID: PMC6937402, PII: 00024382-202003000-00008, DOI: 10.1097/SHK.0000000000001364, ISSN: 1540-0514.
Fukuda S, Ihara K, Bohannon JK, Hernandez A, Patil NK, Luan L, Stothers C, Stark R, Prough DS, Herndon DN, Sherwood ER, Enkhbaatar P. Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep. Shock. 2020 Mar; 53(3): 307-16. PMID: 31045990, PMCID: PMC6937402, PII: 00024382-202003000-00008, DOI: 10.1097/SHK.0000000000001364, ISSN: 1540-0514.
Owen AM, Fults JB, Patil NK, Hernandez A, Bohannon JK. TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection. Front Immunol. 2020; 11: 622614. PMID: 33679711, PMCID: PMC7930332, DOI: 10.3389/fimmu.2020.622614, ISSN: 1664-3224.
McBride MA, Patil TK, Bohannon JK, Hernandez A, Sherwood ER, Patil NK. Immune Checkpoints: Novel Therapeutic Targets to Attenuate Sepsis-Induced Immunosuppression. Front Immunol. 2020; 11: 624272. PMID: 33613563, PMCID: PMC7886986, DOI: 10.3389/fimmu.2020.624272, ISSN: 1664-3224.
McBride MA, Owen AM, Stothers CL, Hernandez A, Luan L, Burelbach KR, Patil TK, Bohannon JK, Sherwood ER, Patil NK. The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma. Front Immunol. 2020; 11: 1043. PMID: 32547553, PMCID: PMC7273750, DOI: 10.3389/fimmu.2020.01043, ISSN: 1664-3224.
McBride MA, Owen AM, Stothers CL, Hernandez A, Luan L, Burelbach KR, Patil TK, Bohannon JK, Sherwood ER, Patil NK. The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma. Front Immunol. 2020; 11: 1043. PMID: 32547553, PMCID: PMC7273750, DOI: 10.3389/fimmu.2020.01043, ISSN: 1664-3224.
McBride MA, Patil TK, Bohannon JK, Hernandez A, Sherwood ER, Patil NK. Immune Checkpoints: Novel Therapeutic Targets to Attenuate Sepsis-Induced Immunosuppression. Front Immunol. 2020; 11: 624272. PMID: 33613563, PMCID: PMC7886986, DOI: 10.3389/fimmu.2020.624272, ISSN: 1664-3224.
Owen AM, Fults JB, Patil NK, Hernandez A, Bohannon JK. TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection. Front Immunol. 2020; 11: 622614. PMID: 33679711, PMCID: PMC7930332, DOI: 10.3389/fimmu.2020.622614, ISSN: 1664-3224.
Hernandez A, Patil NK, Stothers CL, Luan L, McBride MA, Owen AM, Burelbach KR, Williams DL, Sherwood ER, Bohannon JK. Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection. Pharmacol Res [print-electronic]. 2019 Dec; 150: 104502. PMID: 31689522, PMCID: PMC6884699, PII: S1043-6618(19)32006-7, DOI: 10.1016/j.phrs.2019.104502, ISSN: 1096-1186.
Hernandez A, Patil NK, Stothers CL, Luan L, McBride MA, Owen AM, Burelbach KR, Williams DL, Sherwood ER, Bohannon JK. Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection. Pharmacol Res [print-electronic]. 2019 Dec; 150: 104502. PMID: 31689522, PMCID: PMC6884699, PII: S1043-6618(19)32006-7, DOI: 10.1016/j.phrs.2019.104502, ISSN: 1096-1186.
Hernandez A, Luan L, Stothers CL, Patil NK, Fults JB, Fensterheim BA, Guo Y, Wang J, Sherwood ER, Bohannon JK. Phosphorylated Hexa-Acyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens. Crit Care Med. 2019 Nov; 47(11): e930-e938. PMID: 31567352, PMCID: PMC6791756, DOI: 10.1097/CCM.0000000000003967, ISSN: 1530-0293.
Hernandez A, Luan L, Stothers CL, Patil NK, Fults JB, Fensterheim BA, Guo Y, Wang J, Sherwood ER, Bohannon JK. Phosphorylated Hexa-Acyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens. Crit Care Med. 2019 Nov; 47(11): e930-e938-e938. PMID: 31567352, PMCID: PMC6791756, DOI: 10.1097/CCM.0000000000003967, ISSN: 1530-0293.
Patil NK, Bohannon JK, Hernandez A, Patil TK, Sherwood ER. Regulation of leukocyte function by citric acid cycle intermediates. J Leukoc Biol [print-electronic]. 2019 Jul; 106(1): 105-17. PMID: 30791134, PMCID: PMC6597293, DOI: 10.1002/JLB.3MIR1118-415R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Hernandez A, Patil TK, Sherwood ER. Regulation of leukocyte function by citric acid cycle intermediates. J Leukoc Biol [print-electronic]. 2019 Jul; 106(1): 105-17. PMID: 30791134, PMCID: PMC6597293, DOI: 10.1002/JLB.3MIR1118-415R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Metabolism drives monocytes during inflammation: What we do and do not know [editorial]. J Leukoc Biol [print-electronic]. 2019 Feb; 105(2): 211-3. PMID: 30618209, DOI: 10.1002/JLB.3CE1118-448R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Metabolism drives monocytes during inflammation: What we do and do not know [editorial]. J Leukoc Biol [print-electronic]. 2019 Feb; 105(2): 211-3. PMID: 30618209, DOI: 10.1002/JLB.3CE1118-448R, ISSN: 1938-3673.
Stothers CL, Luan L, Fensterheim BA, Bohannon JK. Hypoxia-inducible factor-1a regulation of myeloid cells. J. Mol. Med [print-electronic]. 2018 Dec; 96(12): 1293-306. PMID: 30386909, PMCID: PMC6292431, PII: 10.1007/s00109-018-1710-1, DOI: 10.1007/s00109-018-1710-1, ISSN: 1432-1440.
Bohannon JK, Sherwood ER. What's New in Shock, July 2018?. Shock. 2018 Jul; 50(1): 1-4. PMID: 29889806, PII: 00024382-201807000-00001, DOI: 10.1097/SHK.0000000000001153, ISSN: 1540-0514.
Fensterheim BA, Young JD, Luan L, Kleinbard RR, Stothers CL, Patil NK, McAtee-Pereira AG, Guo Y, Trenary I, Hernandez A, Fults JB, Williams DL, Sherwood ER, Bohannon JK. The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. J. Immunol [print-electronic]. 2018 Jun 6/1/2018; 200(11): 3777-89. PMID: 29686054, PMCID: PMC5964009, PII: jimmunol.1800085, DOI: 10.4049/jimmunol.1800085, ISSN: 1550-6606.
Guo Y, Patil NK, Luan L, Bohannon JK, Sherwood ER. The biology of natural killer cells during sepsis. Immunology [print-electronic]. 2018 Feb; 153(2): 190-202. PMID: 29064085, PMCID: PMC5765373, DOI: 10.1111/imm.12854, ISSN: 1365-2567.
Patil NK, Luan L, Bohannon JK, Hernandez A, Guo Y, Sherwood ER. Frontline Science: Anti-PD-L1 protects against infection with common bacterial pathogens after burn injury. J. Leukoc. Biol [print-electronic]. 2018 Jan; 103(1): 23-33. PMID: 29345058, DOI: 10.1002/JLB.5HI0917-360R, ISSN: 1938-3673.
Fensterheim BA, Guo Y, Sherwood ER, Bohannon JK. The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection. J. Immunol [print-electronic]. 2017 Apr 4/15/2017; 198(8): 3264-73. PMID: 28275139, PMCID: PMC5380530, PII: jimmunol.1602106, DOI: 10.4049/jimmunol.1602106, ISSN: 1550-6606.
Bae L, Bohannon JK, Cui W, Vinish M, Toliver-Kinsky T. Fms-like tyrosine kinase-3 ligand increases resistance to burn wound infection through effects on plasmacytoid dendritic cells. BMC Immunol. 2017 Feb 2/22/2017; 18(1): 9. PMID: 28228109, PMCID: PMC5322596, PII: 10.1186/s12865-016-0188-2, DOI: 10.1186/s12865-016-0188-2, ISSN: 1471-2172.
Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W, Fensterheim BA, Hernandez A, Sherwood ER. IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function. J. Immunol [print-electronic]. 2017 Feb 2/1/2017; 198(3): 1320-33. PMID: 28031340, PMCID: PMC5263185, PII: jimmunol.1601486, DOI: 10.4049/jimmunol.1601486, ISSN: 1550-6606.
Luan L, Patil NK, Guo Y, Hernandez A, Bohannon JK, Fensterheim BA, Wang J, Xu Y, Enkhbaatar P, Stark R, Sherwood ER. Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A. Sci Rep. 2017 Jan 1/5/2017; 7: 40050. PMID: 28053314, PMCID: PMC5215261, PII: srep40050, DOI: 10.1038/srep40050, ISSN: 2045-2322.
Patil NK, Bohannon JK, Luan L, Guo Y, Fensterheim B, Hernandez A, Wang J, Sherwood ER. Flt3 Ligand Treatment Attenuates T Cell Dysfunction and Improves Survival in a Murine Model of Burn Wound Sepsis. Shock. 2017 Jan; 47(1): 40-51. PMID: 27454384, PMCID: PMC5167662, DOI: 10.1097/SHK.0000000000000688, ISSN: 1540-0514.
Bohannon JK, Sherwood ER. Editorial: Feeling the burn: sphingolipids and infection risk after thermal injury [editorial]. J. Leukoc. Biol. 2016 Dec; 100(6): 1227-8. PMID: 27909176, PII: 100/6/1227, DOI: 10.1189/jlb.4CE0716-299R, ISSN: 1938-3673.
Hernandez A, Bohannon JK, Luan L, Fensterheim BA, Guo Y, Patil NK, McAdams C, Wang J, Sherwood ER. The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. J. Leukoc. Biol [print-electronic]. 2016 Dec; 100(6): 1311-22. PMID: 27354411, PMCID: PMC5109999, PII: jlb.1A0216-072R, DOI: 10.1189/jlb.1A0216-072R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Immunotherapy: A promising approach to reverse sepsis-induced immunosuppression. Pharmacol. Res [print-electronic]. 2016 Sep; 111: 688-702. PMID: 27468649, PMCID: PMC5026606, PII: S1043-6618(16)30685-5, DOI: 10.1016/j.phrs.2016.07.019, ISSN: 1096-1186.
Bohannon JK, Luan L, Hernandez A, Afzal A, Guo Y, Patil NK, Fensterheim B, Sherwood ER. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. J. Leukoc. Biol [print-electronic]. 2016 Apr; 99(4): 629-40. PMID: 26538529, PMCID: PMC4787290, PII: jlb.4A0815-362R, DOI: 10.1189/jlb.4A0815-362R, ISSN: 1938-3673.
Patil NK, Luan L, Bohannon JK, Guo Y, Hernandez A, Fensterheim B, Sherwood ER. IL-15 Superagonist Expands mCD8+ T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection. PLoS ONE. 2016; 11(2): e0148452. PMID: 26859674, PMCID: PMC4747596, PII: PONE-D-15-47311, DOI: 10.1371/journal.pone.0148452, ISSN: 1932-6203.
Guo Y, Luan L, Rabacal W, Bohannon JK, Fensterheim BA, Hernandez A, Sherwood ER. IL-15 Superagonist-Mediated Immunotoxicity: Role of NK Cells and IFN-¿. J. Immunol [print-electronic]. 2015 Sep 9/1/2015; 195(5): 2353-64. PMID: 26216888, PMCID: PMC4543906, PII: jimmunol.1500300, DOI: 10.4049/jimmunol.1500300, ISSN: 1550-6606.
Bohannon JK, Hernandez A, Enkhbaatar P, Adams WL, Sherwood ER. The immunobiology of toll-like receptor 4 agonists: from endotoxin tolerance to immunoadjuvants. Shock. 2013 Dec; 40(6): 451-62. PMID: 23989337, PMCID: PMC3919163, DOI: 10.1097/SHK.0000000000000042, ISSN: 1540-0514.
Hao D, McBride MA, Bohannon JK, Hernandez A, Klein B, Williams DL, Sherwood ER. Metabolic adaptations driving innate immune memory: mechanisms and therapeutic implications. J Leukoc Biol. 2025 May 5/7/2025; 117(5): PMID: 40138361, PMCID: PMC12094284, PII: 8095364, DOI: 10.1093/jleuko/qiaf037, ISSN: 1938-3673.
Hao D, Caja KR, McBride MA, Owen AM, Bohannon JK, Hernandez A, Ali S, Dalal S, Williams DL, Sherwood ER. Trained immunity enhances host resistance to infection in aged mice. J Leukoc Biol. 2025 Apr 4/23/2025; 117(4): PMID: 39722231, PMCID: PMC12022634, PII: 7932571, DOI: 10.1093/jleuko/qiae259, ISSN: 1938-3673.
McBride MA, Caja KR, Patil TK, Owen AM, Luan L, Bohannon JK, Hernandez A, Stothers CL, Trenary IA, Rahim M, Young JD, Calcutt MW, Stephens VR, Davis X, Oliver MA, Hao D, Si C, McRae M, Nguyen KK, Davis NS, Wang J, Patil NK, Sherwood ER. Immunoresponsive gene 1 facilitates TLR4 agonist-induced augmentation of innate antimicrobial immunity. J Leukoc Biol. 2025 Feb 2/13/2025; 117(2): PMID: 39351765, PMCID: PMC11879002, PII: 7798214, DOI: 10.1093/jleuko/qiae198, ISSN: 1938-3673.
Nabukhotna K, Kordus SL, Shupe JA, Cano Rodríguez R, Smith A, Bohannon JK, Washington MK, Lacy DB. Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection. PLoS Pathog. 2024 Sep; 20(9): e1012568. PMID: 39298531, PMCID: PMC11444381, PII: PPATHOGENS-D-24-01481, DOI: 10.1371/journal.ppat.1012568, ISSN: 1553-7374.
Oliver MA, Davis XD, Bohannon JK. TGFß macrophage reprogramming: a new dimension of macrophage plasticity. J Leukoc Biol. 2024 Feb 2/23/2024; 115(3): 411-4. PMID: 38197509, PMCID: PMC11423798, PII: 7513893, DOI: 10.1093/jleuko/qiae001, ISSN: 1938-3673.
McBride MA, Stothers CL, Fensterheim BA, Caja KR, Owen AM, Hernandez A, Bohannon JK, Patil NK, Ali S, Dalal S, Rahim M, Trenary IA, Young JD, Williams DL, Sherwood ER. Bacteria- and fungus-derived PAMPs induce innate immune memory via similar functional, metabolic, and transcriptional adaptations. J Leukoc Biol. 2024 Jan 1/19/2024; 115(2): 358-73. PMID: 37793181, PMCID: PMC10872320, PII: 7289224, DOI: 10.1093/jleuko/qiad120, ISSN: 1938-3673.
Schaaf KR, Landstreet SR, Pugazenthi S, Qian EY, Putz ND, Siderova T, Owen AM, Bohannon JK, Ware LB, Bastarache JA, Shaver CM. Cell-free hemoglobin triggers macrophage cytokine production via TLR4 and MyD88. Am J Physiol Lung Cell Mol Physiol [print-electronic]. 2024 Jan 1/1/2024; 326(1): L29-L38-L38. PMID: 37991487, PMCID: PMC11279742, DOI: 10.1152/ajplung.00123.2023, ISSN: 1522-1504.
Hernandez A, Patil NK, Brewer M, Delgado R, Himmel L, Lopez LN, Bohannon JK, Owen AM, Sherwood ER, de Caestecker MP. Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol [print-electronic]. 2023 May 5/1/2023; 324(5): F472-F482-F482. PMID: 36995924, PMCID: PMC10151043, DOI: 10.1152/ajprenal.00248.2022, ISSN: 1522-1466.
Hernandez A, Zhou J, Bohannon JK, McBride MA, Gibson-Corley KN, Patil NK, Owen AM, Burelbach KR, Sherwood ER. INTRAPULMONARY TREATMENT WITH A NOVEL TLR4 AGONIST CONFERS PROTECTION AGAINST KLEBSIELLA PNEUMONIA. Shock [print-electronic]. 2022 Oct 10/1/2022; 58(4): 295-303. PMID: 36018281, PII: 00024382-202210000-00007, DOI: 10.1097/SHK.0000000000001977, ISSN: 1540-0514.
Hernandez A, Zhou J, Bohannon JK, McBride MA, Gibson-Corley KN, Patil NK, Owen AM, Burelbach KR, Sherwood ER. INTRAPULMONARY TREATMENT WITH A NOVEL TLR4 AGONIST CONFERS PROTECTION AGAINST KLEBSIELLA PNEUMONIA. Shock [print-electronic]. 2022 Oct 10/1/2022; 58(4): 295-303. PMID: 36018281, PMCID: PMC9647733, PII: 00024382-202210000-00007, DOI: 10.1097/SHK.0000000000001977, ISSN: 1540-0514.
Burmeister DM, Supp DM, Clark RA, Tredget EE, Powell HM, Enkhbaatar P, Bohannon JK, Cancio LC, Hill DM, Nygaard RM. Advantages and Disadvantages of Using Small and Large Animals in Burn Research: Proceedings of the 2021 Research Special Interest Group. J Burn Care Res. 2022 Sep 9/1/2022; 43(5): 1032-41. PMID: 35778269, PII: 6626055, DOI: 10.1093/jbcr/irac091, ISSN: 1559-0488.
Burmeister DM, Supp DM, Clark RA, Tredget EE, Powell HM, Enkhbaatar P, Bohannon JK, Cancio LC, Hill DM, Nygaard RM. Advantages and Disadvantages of Using Small and Large Animals in Burn Research: Proceedings of the 2021 Research Special Interest Group. J Burn Care Res. 2022 Sep 9/1/2022; 43(5): 1032-41. PMID: 35778269, PII: 6626055, DOI: 10.1093/jbcr/irac091, ISSN: 1559-0488.
Sherwood ER, Burelbach KR, McBride MA, Stothers CL, Owen AM, Hernandez A, Patil NK, Williams DL, Bohannon JK. Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 Feb 2/15/2022; 208(4): 785-92. PMID: 35115374, PMCID: PMC8982914, PII: jimmunol.2101058, DOI: 10.4049/jimmunol.2101058, ISSN: 1550-6606.
Sherwood ER, Burelbach KR, McBride MA, Stothers CL, Owen AM, Hernandez A, Patil NK, Williams DL, Bohannon JK. Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 Feb 2/15/2022; 208(4): 785-92. PMID: 35115374, PMCID: PMC8982914, PII: jimmunol.2101058, DOI: 10.4049/jimmunol.2101058, ISSN: 1550-6606.
Patil NK, Bohannon JK, Vachharajani V, McCall CE. Editorial: The Roles of Mitochondria in Immunity [editorial]. Front Immunol. 2022; 13: 914639. PMID: 35651600, PMCID: PMC9149419, DOI: 10.3389/fimmu.2022.914639, ISSN: 1664-3224.
Patil NK, Bohannon JK, Vachharajani V, McCall CE. Editorial: The Roles of Mitochondria in Immunity [editorial]. Front Immunol. 2022; 13: 914639. PMID: 35651600, PMCID: PMC9149419, DOI: 10.3389/fimmu.2022.914639, ISSN: 1664-3224.
Owen AM, Luan L, Burelbach KR, McBride MA, Stothers CL, Boykin OA, Sivanesam K, Schaedel JF, Patil TK, Wang J, Hernandez A, Patil NK, Sherwood ER, Bohannon JK. MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages. Front Immunol. 2022; 13: 1044662. PMID: 36439136, PMCID: PMC9692127, DOI: 10.3389/fimmu.2022.1044662, ISSN: 1664-3224.
Stothers CL, Burelbach KR, Owen AM, Patil NK, McBride MA, Bohannon JK, Luan L, Hernandez A, Patil TK, Williams DL, Sherwood ER. ß-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages. J Immunol [print-electronic]. 2021 Dec 12/1/2021; 207(11): 2785-98. PMID: 34740960, PMCID: PMC8612974, PII: jimmunol.2100107, DOI: 10.4049/jimmunol.2100107, ISSN: 1550-6606.
Stothers CL, Burelbach KR, Owen AM, Patil NK, McBride MA, Bohannon JK, Luan L, Hernandez A, Patil TK, Williams DL, Sherwood ER. ß-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages. J Immunol [print-electronic]. 2021 Dec 12/1/2021; 207(11): 2785-98. PMID: 34740960, PMCID: PMC8612974, PII: jimmunol.2100107, DOI: 10.4049/jimmunol.2100107, ISSN: 1550-6606.
Bohannon JK, Sherwood ER. What's New in Shock, April 2021?. Shock. 2021 Apr 4/1/2021; 55(4): 419-22. PMID: 33730006, PII: 00024382-202104000-00001, DOI: 10.1097/SHK.0000000000001760, ISSN: 1540-0514.
Bohannon JK, Sherwood ER. What's New in Shock, April 2021?. Shock. 2021 Apr 4/1/2021; 55(4): 419-22. PMID: 33730006, PII: 00024382-202104000-00001, DOI: 10.1097/SHK.0000000000001760, ISSN: 1540-0514.
Hernandez A, Patil NK, Bohannon JK. A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection. Methods Mol Biol. 2021; 2321: 111-20. PMID: 34048011, PMCID: PMC9057493, DOI: 10.1007/978-1-0716-1488-4_10, ISSN: 1940-6029.
Hernandez A, Patil NK, Bohannon JK. A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection. Methods Mol Biol. 2021; 2321: 111-20. PMID: 34048011, PMCID: PMC9057493, DOI: 10.1007/978-1-0716-1488-4_10, ISSN: 1940-6029.
Fukuda S, Ihara K, Bohannon JK, Hernandez A, Patil NK, Luan L, Stothers C, Stark R, Prough DS, Herndon DN, Sherwood ER, Enkhbaatar P. Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep. Shock. 2020 Mar; 53(3): 307-16. PMID: 31045990, PMCID: PMC6937402, PII: 00024382-202003000-00008, DOI: 10.1097/SHK.0000000000001364, ISSN: 1540-0514.
Fukuda S, Ihara K, Bohannon JK, Hernandez A, Patil NK, Luan L, Stothers C, Stark R, Prough DS, Herndon DN, Sherwood ER, Enkhbaatar P. Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep. Shock. 2020 Mar; 53(3): 307-16. PMID: 31045990, PMCID: PMC6937402, PII: 00024382-202003000-00008, DOI: 10.1097/SHK.0000000000001364, ISSN: 1540-0514.
Owen AM, Fults JB, Patil NK, Hernandez A, Bohannon JK. TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection. Front Immunol. 2020; 11: 622614. PMID: 33679711, PMCID: PMC7930332, DOI: 10.3389/fimmu.2020.622614, ISSN: 1664-3224.
McBride MA, Patil TK, Bohannon JK, Hernandez A, Sherwood ER, Patil NK. Immune Checkpoints: Novel Therapeutic Targets to Attenuate Sepsis-Induced Immunosuppression. Front Immunol. 2020; 11: 624272. PMID: 33613563, PMCID: PMC7886986, DOI: 10.3389/fimmu.2020.624272, ISSN: 1664-3224.
McBride MA, Owen AM, Stothers CL, Hernandez A, Luan L, Burelbach KR, Patil TK, Bohannon JK, Sherwood ER, Patil NK. The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma. Front Immunol. 2020; 11: 1043. PMID: 32547553, PMCID: PMC7273750, DOI: 10.3389/fimmu.2020.01043, ISSN: 1664-3224.
McBride MA, Owen AM, Stothers CL, Hernandez A, Luan L, Burelbach KR, Patil TK, Bohannon JK, Sherwood ER, Patil NK. The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma. Front Immunol. 2020; 11: 1043. PMID: 32547553, PMCID: PMC7273750, DOI: 10.3389/fimmu.2020.01043, ISSN: 1664-3224.
McBride MA, Patil TK, Bohannon JK, Hernandez A, Sherwood ER, Patil NK. Immune Checkpoints: Novel Therapeutic Targets to Attenuate Sepsis-Induced Immunosuppression. Front Immunol. 2020; 11: 624272. PMID: 33613563, PMCID: PMC7886986, DOI: 10.3389/fimmu.2020.624272, ISSN: 1664-3224.
Owen AM, Fults JB, Patil NK, Hernandez A, Bohannon JK. TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection. Front Immunol. 2020; 11: 622614. PMID: 33679711, PMCID: PMC7930332, DOI: 10.3389/fimmu.2020.622614, ISSN: 1664-3224.
Hernandez A, Patil NK, Stothers CL, Luan L, McBride MA, Owen AM, Burelbach KR, Williams DL, Sherwood ER, Bohannon JK. Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection. Pharmacol Res [print-electronic]. 2019 Dec; 150: 104502. PMID: 31689522, PMCID: PMC6884699, PII: S1043-6618(19)32006-7, DOI: 10.1016/j.phrs.2019.104502, ISSN: 1096-1186.
Hernandez A, Patil NK, Stothers CL, Luan L, McBride MA, Owen AM, Burelbach KR, Williams DL, Sherwood ER, Bohannon JK. Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection. Pharmacol Res [print-electronic]. 2019 Dec; 150: 104502. PMID: 31689522, PMCID: PMC6884699, PII: S1043-6618(19)32006-7, DOI: 10.1016/j.phrs.2019.104502, ISSN: 1096-1186.
Hernandez A, Luan L, Stothers CL, Patil NK, Fults JB, Fensterheim BA, Guo Y, Wang J, Sherwood ER, Bohannon JK. Phosphorylated Hexa-Acyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens. Crit Care Med. 2019 Nov; 47(11): e930-e938. PMID: 31567352, PMCID: PMC6791756, DOI: 10.1097/CCM.0000000000003967, ISSN: 1530-0293.
Hernandez A, Luan L, Stothers CL, Patil NK, Fults JB, Fensterheim BA, Guo Y, Wang J, Sherwood ER, Bohannon JK. Phosphorylated Hexa-Acyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens. Crit Care Med. 2019 Nov; 47(11): e930-e938-e938. PMID: 31567352, PMCID: PMC6791756, DOI: 10.1097/CCM.0000000000003967, ISSN: 1530-0293.
Patil NK, Bohannon JK, Hernandez A, Patil TK, Sherwood ER. Regulation of leukocyte function by citric acid cycle intermediates. J Leukoc Biol [print-electronic]. 2019 Jul; 106(1): 105-17. PMID: 30791134, PMCID: PMC6597293, DOI: 10.1002/JLB.3MIR1118-415R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Hernandez A, Patil TK, Sherwood ER. Regulation of leukocyte function by citric acid cycle intermediates. J Leukoc Biol [print-electronic]. 2019 Jul; 106(1): 105-17. PMID: 30791134, PMCID: PMC6597293, DOI: 10.1002/JLB.3MIR1118-415R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Metabolism drives monocytes during inflammation: What we do and do not know [editorial]. J Leukoc Biol [print-electronic]. 2019 Feb; 105(2): 211-3. PMID: 30618209, DOI: 10.1002/JLB.3CE1118-448R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Metabolism drives monocytes during inflammation: What we do and do not know [editorial]. J Leukoc Biol [print-electronic]. 2019 Feb; 105(2): 211-3. PMID: 30618209, DOI: 10.1002/JLB.3CE1118-448R, ISSN: 1938-3673.
Stothers CL, Luan L, Fensterheim BA, Bohannon JK. Hypoxia-inducible factor-1a regulation of myeloid cells. J. Mol. Med [print-electronic]. 2018 Dec; 96(12): 1293-306. PMID: 30386909, PMCID: PMC6292431, PII: 10.1007/s00109-018-1710-1, DOI: 10.1007/s00109-018-1710-1, ISSN: 1432-1440.
Bohannon JK, Sherwood ER. What's New in Shock, July 2018?. Shock. 2018 Jul; 50(1): 1-4. PMID: 29889806, PII: 00024382-201807000-00001, DOI: 10.1097/SHK.0000000000001153, ISSN: 1540-0514.
Fensterheim BA, Young JD, Luan L, Kleinbard RR, Stothers CL, Patil NK, McAtee-Pereira AG, Guo Y, Trenary I, Hernandez A, Fults JB, Williams DL, Sherwood ER, Bohannon JK. The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. J. Immunol [print-electronic]. 2018 Jun 6/1/2018; 200(11): 3777-89. PMID: 29686054, PMCID: PMC5964009, PII: jimmunol.1800085, DOI: 10.4049/jimmunol.1800085, ISSN: 1550-6606.
Guo Y, Patil NK, Luan L, Bohannon JK, Sherwood ER. The biology of natural killer cells during sepsis. Immunology [print-electronic]. 2018 Feb; 153(2): 190-202. PMID: 29064085, PMCID: PMC5765373, DOI: 10.1111/imm.12854, ISSN: 1365-2567.
Patil NK, Luan L, Bohannon JK, Hernandez A, Guo Y, Sherwood ER. Frontline Science: Anti-PD-L1 protects against infection with common bacterial pathogens after burn injury. J. Leukoc. Biol [print-electronic]. 2018 Jan; 103(1): 23-33. PMID: 29345058, DOI: 10.1002/JLB.5HI0917-360R, ISSN: 1938-3673.
Fensterheim BA, Guo Y, Sherwood ER, Bohannon JK. The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection. J. Immunol [print-electronic]. 2017 Apr 4/15/2017; 198(8): 3264-73. PMID: 28275139, PMCID: PMC5380530, PII: jimmunol.1602106, DOI: 10.4049/jimmunol.1602106, ISSN: 1550-6606.
Bae L, Bohannon JK, Cui W, Vinish M, Toliver-Kinsky T. Fms-like tyrosine kinase-3 ligand increases resistance to burn wound infection through effects on plasmacytoid dendritic cells. BMC Immunol. 2017 Feb 2/22/2017; 18(1): 9. PMID: 28228109, PMCID: PMC5322596, PII: 10.1186/s12865-016-0188-2, DOI: 10.1186/s12865-016-0188-2, ISSN: 1471-2172.
Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W, Fensterheim BA, Hernandez A, Sherwood ER. IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function. J. Immunol [print-electronic]. 2017 Feb 2/1/2017; 198(3): 1320-33. PMID: 28031340, PMCID: PMC5263185, PII: jimmunol.1601486, DOI: 10.4049/jimmunol.1601486, ISSN: 1550-6606.
Luan L, Patil NK, Guo Y, Hernandez A, Bohannon JK, Fensterheim BA, Wang J, Xu Y, Enkhbaatar P, Stark R, Sherwood ER. Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A. Sci Rep. 2017 Jan 1/5/2017; 7: 40050. PMID: 28053314, PMCID: PMC5215261, PII: srep40050, DOI: 10.1038/srep40050, ISSN: 2045-2322.
Patil NK, Bohannon JK, Luan L, Guo Y, Fensterheim B, Hernandez A, Wang J, Sherwood ER. Flt3 Ligand Treatment Attenuates T Cell Dysfunction and Improves Survival in a Murine Model of Burn Wound Sepsis. Shock. 2017 Jan; 47(1): 40-51. PMID: 27454384, PMCID: PMC5167662, DOI: 10.1097/SHK.0000000000000688, ISSN: 1540-0514.
Bohannon JK, Sherwood ER. Editorial: Feeling the burn: sphingolipids and infection risk after thermal injury [editorial]. J. Leukoc. Biol. 2016 Dec; 100(6): 1227-8. PMID: 27909176, PII: 100/6/1227, DOI: 10.1189/jlb.4CE0716-299R, ISSN: 1938-3673.
Hernandez A, Bohannon JK, Luan L, Fensterheim BA, Guo Y, Patil NK, McAdams C, Wang J, Sherwood ER. The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. J. Leukoc. Biol [print-electronic]. 2016 Dec; 100(6): 1311-22. PMID: 27354411, PMCID: PMC5109999, PII: jlb.1A0216-072R, DOI: 10.1189/jlb.1A0216-072R, ISSN: 1938-3673.
Patil NK, Bohannon JK, Sherwood ER. Immunotherapy: A promising approach to reverse sepsis-induced immunosuppression. Pharmacol. Res [print-electronic]. 2016 Sep; 111: 688-702. PMID: 27468649, PMCID: PMC5026606, PII: S1043-6618(16)30685-5, DOI: 10.1016/j.phrs.2016.07.019, ISSN: 1096-1186.
Bohannon JK, Luan L, Hernandez A, Afzal A, Guo Y, Patil NK, Fensterheim B, Sherwood ER. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. J. Leukoc. Biol [print-electronic]. 2016 Apr; 99(4): 629-40. PMID: 26538529, PMCID: PMC4787290, PII: jlb.4A0815-362R, DOI: 10.1189/jlb.4A0815-362R, ISSN: 1938-3673.
Patil NK, Luan L, Bohannon JK, Guo Y, Hernandez A, Fensterheim B, Sherwood ER. IL-15 Superagonist Expands mCD8+ T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection. PLoS ONE. 2016; 11(2): e0148452. PMID: 26859674, PMCID: PMC4747596, PII: PONE-D-15-47311, DOI: 10.1371/journal.pone.0148452, ISSN: 1932-6203.
Guo Y, Luan L, Rabacal W, Bohannon JK, Fensterheim BA, Hernandez A, Sherwood ER. IL-15 Superagonist-Mediated Immunotoxicity: Role of NK Cells and IFN-¿. J. Immunol [print-electronic]. 2015 Sep 9/1/2015; 195(5): 2353-64. PMID: 26216888, PMCID: PMC4543906, PII: jimmunol.1500300, DOI: 10.4049/jimmunol.1500300, ISSN: 1550-6606.
Bohannon JK, Hernandez A, Enkhbaatar P, Adams WL, Sherwood ER. The immunobiology of toll-like receptor 4 agonists: from endotoxin tolerance to immunoadjuvants. Shock. 2013 Dec; 40(6): 451-62. PMID: 23989337, PMCID: PMC3919163, DOI: 10.1097/SHK.0000000000000042, ISSN: 1540-0514.