Michael L. Schulte, Ph.D.

Research Assistant Professor

michael.l.schulte@vanderbilt.edu
Faculty Appointments
Research Assistant Professor of Pharmacology
Education
Ph.D., Chemistry , Vanderbilt University, Nashville, TennesseeB.S., Chemistry, Indiana State University, Terre Haute, Indiana
Research Description
Michael Schulte, Ph.D., earned his B.S. in Chemistry from Indiana State University and his Ph.D. in Chemistry from Vanderbilt University. After completing a Postdoctoral Fellowship at Vanderbilt University Institute of Imaging Science, he joined the Vanderbilt faculty as Research Instructor. His research is focused on the design and synthesis of small molecules with the goal of translating them into precision imaging agents for cancer. He is a member of American Chemical Society, World Molecular Imaging Society, Society of Radiopharmaceutical Sciences and the Society of Nuclear Medicine.

Section: Vanderbilt University Institute of Imaging Science
Publications
Li J, Schulte ML, Nickels ML, Manning HC. New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO. Bioorg. Med. Chem. Lett [print-electronic]. 2016 Aug 8/1/2016; 26(15): 3472-7. PMID: 27353534, PII: S0960-894X(16)30652-7, DOI: 10.1016/j.bmcl.2016.06.041, ISSN: 1464-3405.

Schulte ML, Khodadadi AB, Cuthbertson ML, Smith JA, Manning HC. 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Bioorg. Med. Chem. Lett [print-electronic]. 2016 Feb 2/1/2016; 26(3): 1044-7. PMID: 26750251, PMCID: PMC4727990, PII: S0960-894X(15)30345-0, DOI: 10.1016/j.bmcl.2015.12.031, ISSN: 1464-3405.

Schulte ML, Dawson ES, Saleh SA, Cuthbertson ML, Manning HC. 2-Substituted N¿-glutamylanilides as novel probes of ASCT2 with improved potency. Bioorg. Med. Chem. Lett [print-electronic]. 2015 Jan 1/1/2015; 25(1): 113-6. PMID: 25435145, PMCID: PMC4372298, PII: S0960-894X(14)01169-X, DOI: 10.1016/j.bmcl.2014.10.098, ISSN: 1464-3405.

Wen W, Young SE, Duvernay MT, Schulte ML, Nance KD, Melancon BJ, Engers J, Locuson CW, Wood MR, Daniels JS, Wu W, Lindsley CW, Hamm HE, Stauffer SR. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorg. Med. Chem. Lett [print-electronic]. 2014 Oct 10/1/2014; 24(19): 4708-13. PMID: 25176330, PII: S0960-894X(14)00852-X, DOI: 10.1016/j.bmcl.2014.08.021, ISSN: 1464-3405.

Uddin MI, Buck JR, Schulte ML, Tang D, Saleh SA, Cheung YY, Harp J, Manning HC. Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes. Tetrahedron Lett. 2014 Jan 1/1/2014; 55(1): PMID: 24396154, PMCID: PMC3880151, DOI: 10.1016/j.tetlet.2013.10.143, ISSN: 0040-4039.