Haley Elizabeth Ramsey, Ph.D.

Research Assistant Professor

Faculty Appointments
Research Assistant Professor of Medicine
Ph.D., Inflammation and Immunology, University of Vienna, Vienna, AustriaM.Sc., Biomedicine, Universit├Ąt Bonn, Bonn, GermanyB.Sc., Ecology and Evolutionary Biology, University of Tennessee, Knoxville, Tennessee
Lee T, Christov PP, Shaw S, Tarr JC, Zhao B, Veerasamy N, Jeon KO, Mills JJ, Bian Z, Sensintaffar JL, Arnold AL, Fogarty SA, Perry E, Ramsey HE, Cook RS, Hollingshead M, Davis Millin M, Lee KM, Koss B, Budhraja A, Opferman JT, Kim K, Arteaga CL, Moore WJ, Olejniczak ET, Savona MR, Fesik SW. Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer. J. Med. Chem [print-electronic]. 2019 Apr 4/16/2019; PMID: 30929420, DOI: 10.1021/acs.jmedchem.8b01991, ISSN: 1520-4804.

Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML. J. Cell. Biochem [print-electronic]. 2018 Nov 11/11/2018; PMID: 30417424, DOI: 10.1002/jcb.28005, ISSN: 1097-4644.

Ramsey HE, Fischer MA, Lee T, Gorska AE, Arrate MP, Fuller L, Boyd KL, Strickland SA, Sensintaffar J, Hogdal LJ, Ayers GD, Olejniczak ET, Fesik SW, Savona MR. A Novel MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistant Acute Myelogenous Leukemia. Cancer Discov [print-electronic]. 2018 Sep 9/5/2018; PMID: 30185627, PII: 2159-8290.CD-18-0140, DOI: 10.1158/2159-8290.CD-18-0140, ISSN: 2159-8290.

Lorenz V, Ramsey H, Liu ZJ, Italiano J, Hoffmeister K, Bihorel S, Mager D, Hu Z, Slayton WB, Kile BT, Sola-Visner M, Ferrer-Marin F. Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice. Thromb. Haemost [print-electronic]. 2017 Dec; 117(12): 2322-33. PMID: 29212120, PMCID: PMC5911346, DOI: 10.1160/TH17-06-0433, ISSN: 2567-689X.

Sparger KA, Ramsey H, Lorenz V, Liu ZJ, Feldman HA, Li N, Laforest T, Sola-Visner MC. Developmental differences between newborn and adult mice in response to romiplostim. Platelets [print-electronic]. 2017 May 5/26/2017; 1-8. PMID: 28548028, DOI: 10.1080/09537104.2017.1316481, ISSN: 1369-1635.

Shahid M, Javed AA, Chandra D, Ramsey HE, Shah D, Khan MF, Zhao L, Wu MX. IEX-1 deficiency induces browning of white adipose tissue and resists diet-induced obesity. Sci Rep. 2016 Apr 4/11/2016; 6: 24135. PMID: 27063893, PMCID: PMC4827096, PII: srep24135, DOI: 10.1038/srep24135, ISSN: 2045-2322.

Gattringer M, Baranyi U, Pilat N, Hock K, Klaus C, Ramsey HE, Wrba F, Valenta R, Wekerle T. Anti-OX40L alone or in combination with anti-CD40L and CTLA4Ig does not inhibit the humoral and cellular response to a major grass pollen allergen. Clin. Exp. Allergy. 2016 Feb; 46(2): 354-64. PMID: 26464312, DOI: 10.1111/cea.12661, ISSN: 1365-2222.

Pilat N, Klaus C, Schwarz C, Hock K, Oberhuber R, Schwaiger E, Gattringer M, Ramsey H, Baranyi U, Zelger B, Brandacher G, Wrba F, Wekerle T. Rapamycin and CTLA4Ig synergize to induce stable mixed chimerism without the need for CD40 blockade. Am. J. Transplant [print-electronic]. 2015 Jun; 15(6): 1568-79. PMID: 25783859, DOI: 10.1111/ajt.13154, ISSN: 1600-6143.

Ramsey H, Zhang Q, Wu MX. Mitoquinone restores platelet production in irradiation-induced thrombocytopenia. Platelets [print-electronic]. 2015; 26(5): 459-66. PMID: 25025394, PMCID: PMC4382457, DOI: 10.3109/09537104.2014.935315, ISSN: 1369-1635.

Ramsey H, Wu MX. Mitochondrial anti-oxidant protects IEX-1 deficient mice from organ damage during endotoxemia. Int. Immunopharmacol. 2014 Dec; 23(2): 658-63. PMID: 25466275, PMCID: PMC4394602, PII: S1567-5769(14)00401-9, DOI: 10.1016/j.intimp.2014.10.019, ISSN: 1878-1705.

Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M. Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan. Blood [print-electronic]. 2014 May 5/29/2014; 123(22): 3381-9. PMID: 24599546, PMCID: PMC4041172, PII: blood-2013-06-508200, DOI: 10.1182/blood-2013-06-508200, ISSN: 1528-0020.

Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX. Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3). Haematologica [print-electronic]. 2014 Feb; 99(2): 282-91. PMID: 24056813, PMCID: PMC3912958, PII: haematol.2013.092452, DOI: 10.3324/haematol.2013.092452, ISSN: 1592-8721.

Gattringer M, Baranyi U, Pilat N, Hock K, Klaus C, Buchberger E, Ramsey H, Iacomini J, Valenta R, Wekerle T. Engraftment of retrovirally transduced Bet v 1-GFP expressing bone marrow cells leads to allergen-specific tolerance. Immunobiology [print-electronic]. 2013 Sep; 218(9): 1139-46. PMID: 23623394, PII: S0171-2985(13)00058-2, DOI: 10.1016/j.imbio.2013.03.007, ISSN: 1878-3279.

Ramsey H, Pilat N, Hock K, Klaus C, Unger L, Schwarz C, Baranyi U, Gattringer M, Schwaiger E, Wrba F, Wekerle T. Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients. Transpl. Int [print-electronic]. 2013 Feb; 26(2): 206-18. PMID: 23240587, DOI: 10.1111/tri.12021, ISSN: 1432-2277.

Schwaiger E, Klaus C, Matheeussen V, Baranyi U, Pilat N, Ramsey H, Korom S, De Meester I, Wekerle T. Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning. Exp. Hematol [print-electronic]. 2012 Feb; 40(2): 97-106. PMID: 22085453, PMCID: PMC3265670, PII: S0301-472X(11)00543-1, DOI: 10.1016/j.exphem.2011.10.010, ISSN: 1873-2399.

Damrauer SM, Studer P, da Silva CG, Longo CR, Ramsey HE, Csizmadia E, Shrikhande GV, Scali ST, Libermann TA, Bhasin MK, Ferran C. A20 modulates lipid metabolism and energy production to promote liver regeneration. PLoS ONE. 2011 Mar 3/17/2011; 6(3): e17715. PMID: 21437236, PMCID: PMC3060102, DOI: 10.1371/journal.pone.0017715, ISSN: 1932-6203.

Ramsey HE, Da Silva CG, Longo CR, Csizmadia E, Studer P, Patel VI, Damrauer SM, Siracuse JJ, Daniel S, Ferran C. A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression. Liver Transpl. 2009 Nov; 15(11): 1613-21. PMID: 19877201, PMCID: PMC2976064, DOI: 10.1002/lt.21879, ISSN: 1527-6473.

Daniel S, Patel VI, Shrikhande GV, Scali ST, Ramsey HE, Csizmadia E, Benhaga N, Fisher MD, Arvelo MB, Ferran C. The universal NF-kappaB inhibitor a20 protects from transplant vasculopathy by differentially affecting apoptosis in endothelial and smooth muscle cells. Transplant. Proc. 2006 Dec; 38(10): 3225-7. PMID: 17175229, PMCID: PMC2866740, PII: S0041-1345(06)01415-1, DOI: 10.1016/j.transproceed.2006.10.167, ISSN: 0041-1345.

Patel VI, Daniel S, Longo CR, Shrikhande GV, Scali ST, Czismadia E, Groft CM, Shukri T, Motley-Dore C, Ramsey HE, Fisher MD, Grey ST, Arvelo MB, Ferran C. A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. FASEB J. 2006 Jul; 20(9): 1418-30. PMID: 16816117, PII: 20/9/1418, DOI: 10.1096/fj.05-4981com, ISSN: 1530-6860.