Michael T Byrne, D.O.

Assistant Professor

Faculty Appointments
Assistant Professor of Medicine
D.O., Lake Erie College of Osteopathic Medicine, Erie, PennsylvaniaB.S., Biology, Duquesne University, Pittsburgh, PennsylvaniaB.A., Psychology, Duquesne University, Pittsburgh, Pennsylvania
Tsirigotis P, Byrne M, Schmid C, Baron F, Ciceri F, Esteve J, Gorin NC, Giebel S, Mohty M, Savani BN, Nagler A. Relapse of AML after hematopoietic stem cell transplantation: methods of monitoring and preventive strategies. A review from the ALWP of the EBMT. Bone Marrow Transplant [print-electronic]. 2016 Jun 6/13/2016; PMID: 27295272, PII: bmt2016167, DOI: 10.1038/bmt.2016.167, ISSN: 1476-5365.

Katragadda L, McCullough LM, Dai Y, Hsu J, Byrne M, Hiemenz J, May S, Cogle CR, Norkin M, Brown RA, Wingard JR, Chang M, Moreb JS. Effect of Melphalan 140 mg/m(2) versus 200 mg/m(2) on Toxicities and Outcomes in Multiple Myeloma Patients Undergoing Single Autologous Stem Cell Transplantation - A single center experience. Clin Transplant [print-electronic]. 2016 May 5/24/2016; PMID: 27219740, DOI: 10.1111/ctr.12762, ISSN: 1399-0012.

Byrne M, Savani BN, Mohty M, Nagler A. Peripheral blood stem cell versus bone marrow transplantation: A perspective from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Exp. Hematol [print-electronic]. 2016 Apr 4/19/2016; PMID: 27106798, PII: S0301-472X(16)30077-7, DOI: 10.1016/j.exphem.2016.04.005, ISSN: 1873-2399.

Byrne M, Savani BN. The devil is in the T cells: relapsing after haploidentical hematopoietic cell transplantation. Bone Marrow Transplant [print-electronic]. 2016 Apr 4/18/2016; PMID: 27088377, PII: bmt2016106, DOI: 10.1038/bmt.2016.106, ISSN: 1476-5365.

Byrne M, Savani BN. Hosting an Unruly Guest: The Impact of Late Acute and Chronic Graft-versus-Host Disease. Biol. Blood Marrow Transplant [print-electronic]. 2016 Feb 2/20/2016; PMID: 26903379, PII: S1083-8791(16)00119-1, DOI: 10.1016/j.bbmt.2016.02.014, ISSN: 1523-6536.

Byrne M, Mannis GN, Nair J, Andreadis C. Inferior vena cava filter thrombosis. Clin Case Rep. 2016 Feb; 4(2): 162-4. PMID: 26862415, PMCID: PMC4736520, PII: CCR3418, DOI: 10.1002/ccr3.418, ISSN: 2050-0904.

Byrne J, Byrne M. Hope Is Palliative. Oncologist [print-electronic]. 2015 Nov; 20(11): 1342-3. PMID: 26446237, PII: theoncologist.2015-0274, DOI: 10.1634/theoncologist.2015-0274, ISSN: 1549-490X.

Cheng X, Byrne M, Brown KD, Konopleva MY, Kornblau SM, Bennett RL, May WS. PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice. Blood [print-electronic]. 2015 Sep 9/24/2015; 126(13): 1585-94. PMID: 26202421, PMCID: PMC4582335, PII: blood-2015-03-635227, DOI: 10.1182/blood-2015-03-635227, ISSN: 1528-0020.

Byrne M, Bennett RL, Cheng X, May WS. Progressive genomic instability in the Nup98-HoxD13 model of MDS correlates with loss of the PIG-A gene product. Neoplasia. 2014 Aug; 16(8): 627-33. PMID: 25220590, PMCID: PMC4234872, PII: S1476-5586(14)00091-8, DOI: 10.1016/j.neo.2014.07.004, ISSN: 1476-5586.

Byrne M, Wray J, Reinert B, Wu Y, Nickoloff J, Lee SH, Hromas R, Williamson E. Mechanisms of oncogenic chromosomal translocations. Ann. N. Y. Acad. Sci [print-electronic]. 2014 Mar; 1310: 89-97. PMID: 24528169, DOI: 10.1111/nyas.12370, ISSN: 1749-6632.

Byrne M, Liu X, Carter CM, Zumberg MS. Myelodysplastic syndrome and associated coagulopathy: a case report and review. Blood Coagul. Fibrinolysis. 2014 Mar; 25(2): 172-5. PMID: 23867346, DOI: 10.1097/MBC.0b013e32836419a7, ISSN: 1473-5733.

Byrne M, Salmasinia D, Leather H, Cogle CR, Davis A, Hsu JW, Wiggins L, Chang MN, An Q, Wingard JR, Moreb JS. Tandem Autologous Stem Cell Transplantation for Multiple Myeloma Patients Based on Response to Their First Transplant-A Prospective Phase II Study. Clin Med Insights Oncol. 2014; 8: 101-5. PMID: 25232286, PMCID: PMC4159376, PII: cmo-8-2014-101, DOI: 10.4137/CMO.S16835, ISSN: 1179-5549.

Williamson EA, Wu Y, Singh S, Byrne M, Wray J, Lee SH, Nickoloff JA, Hromas R. The DNA repair component Metnase regulates Chk1 stability. Cell Div. 2014; 9: 1. PMID: 25024738, PMCID: PMC4094783, PII: 1747-1028-9-1, DOI: 10.1186/1747-1028-9-1, ISSN: 1747-1028.

Byrne M, Wingard JR, Moreb JS. Continuous infusion cyclophosphamide and low-dose total body irradiation is a safe and effective conditioning regimen for autologous transplant in multiple myeloma. Transplant. Proc. 2013 Nov; 45(9): 3361-5. PMID: 24182816, PII: S0041-1345(13)00749-5, DOI: 10.1016/j.transproceed.2013.03.054, ISSN: 1873-2623.

Estfan B, Byrne M, Kim R. Sorafenib in advanced hepatocellular carcinoma: hypertension as a potential surrogate marker for efficacy. Am. J. Clin. Oncol. 2013 Aug; 36(4): 319-24. PMID: 22547010, DOI: 10.1097/COC.0b013e3182468039, ISSN: 1537-453X.

Wirk B, Byrne M, Dai Y, Moreb JS. Outcomes of salvage autologous versus allogeneic hematopoietic cell transplantation for relapsed multiple myeloma after initial autologous hematopoietic cell transplantation. J Clin Med Res [print-electronic]. 2013 Jun; 5(3): 174-84. PMID: 23671543, PMCID: PMC3651068, DOI: 10.4021/jocmr1274w, ISSN: 1918-3003.

Liu X, Bennett RL, Cheng X, Byrne M, Reinhard MK, May WS. PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood [print-electronic]. 2013 Apr 4/25/2013; 121(17): 3364-74. PMID: 23403623, PMCID: PMC3637012, PII: blood-2012-09-456400, DOI: 10.1182/blood-2012-09-456400, ISSN: 1528-0020.

Byrne M. Experts among us. J. Clin. Oncol [print-electronic]. 2013 Mar 3/1/2013; 31(7): 966-8. PMID: 23295804, PII: JCO.2012.47.0641, DOI: 10.1200/JCO.2012.47.0641, ISSN: 1527-7755.

Cheng X, Bennett RL, Liu X, Byrne M, Stratford May W. PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis. Blood Cancer J. 2013; 3: e144. PMID: 24013665, PMCID: PMC3789206, PII: bcj201342, DOI: 10.1038/bcj.2013.42, ISSN: 2044-5385.

Byrne M, Zumberg M. Intentional low-molecular-weight heparin overdose: a case report and review. Blood Coagul. Fibrinolysis. 2012 Dec; 23(8): 772-4. PMID: 23135382, PII: 00001721-201212000-00017, DOI: 10.1097/MBC.0b013e328358e8af, ISSN: 1473-5733.

Liu X, Jiang W, Aucejo F, Kim R, Miller C, Byrne M, Lopez R, Yerian L. Insulin-like growth factor I receptor ß expression in hepatocellular carcinoma. Hum. Pathol [print-electronic]. 2011 Jun; 42(6): 882-91. PMID: 21292299, PII: S0046-8177(10)00387-4, DOI: 10.1016/j.humpath.2010.10.007, ISSN: 1532-8392.

Kim R, Byrne MT, Tan A, Aucejo F. What is the indication for sorafenib in hepatocellular carcinoma? A clinical challenge. Oncology (Williston Park, N.Y.). 2011 Mar; 25(3): 283-91, 295. PMID: 21548473, PII: 167493, ISSN: 0890-9091.

Kim R, Tsao R, Tan A, Byrne M, Almhanna K, Lazaryan A, Elson P, Pelley RJ. A single institution review of adjuvant therapy outcomes for resectable pancreatic adenocarcinoma: outcome and prognostic indicators. J. Gastrointest. Surg [print-electronic]. 2010 Jul; 14(7): 1159-69. PMID: 20446118, DOI: 10.1007/s11605-010-1213-z, ISSN: 1873-4626.

Kim R, El-Gazzaz G, Tan A, Elson P, Byrne M, Chang YD, Aucejo F. Safety and feasibility of using sorafenib in recurrent hepatocellular carcinoma after orthotopic liver transplantation. Oncology [print-electronic]. 2010; 79(1-2): 62-6. PMID: 21071991, PII: 000319548, DOI: 10.1159/000319548, ISSN: 1423-0232.

Byrne MT, Bergman AK, Ruiz AI, Silver BJ, Maciejewski JP, Tiu RV. Postsplenectomy thromboembolic disease in congenital sideroblastic anaemia. BMJ Case Rep. 2010; 2010: PMID: 22778251, PMCID: PMC3027374, PII: 2010/sep16_1/bcr1220092514, DOI: 10.1136/bcr.12.2009.2514, ISSN: 1757-790X.