MD Imam Uddin, Ph.D.

Research Instructor

md.i.uddin@vanderbilt.edu
Faculty Appointments
Research Instructor in Ophthalmology and Visual Sciences
Education
Ph.D., Synthetic Organic Chemistry, Kochi University, Kochi, ForeignM.S., Synthetic Organic Chemistry, Jahangirnagar University, Dacca, BangladeshB.S., Chemistry, Jahangirnagar University, Dacca, Bangladesh
Publications
Uddin MI, Jayagopal A, Wong A, McCollum GW, Wright DW, Penn JS. Real-time imaging of VCAM-1 mRNA in TNF-a activated retinal microvascular endothelial cells using antisense hairpin-DNA functionalized gold nanoparticles. Nanomedicine [print-electronic]. 2018 Jan; 14(1): 63-71. PMID: 28890107, PMCID: PMC5742066, PII: S1549-9634(17)30165-X, DOI: 10.1016/j.nano.2017.08.018, ISSN: 1549-9642.

Uddin MI, Jayagopal A, McCollum GW, Yang R, Penn JS. In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO). Invest. Ophthalmol. Vis. Sci. 2017 Jul 7/1/2017; 58(9): 3818-24. PMID: 28750413, PMCID: PMC5531786, PII: 2646756, DOI: 10.1167/iovs.16-21187, ISSN: 1552-5783.

Uddin MI, Evans SM, Craft JR, Capozzi ME, McCollum GW, Yang R, Marnett LJ, Uddin MJ, Jayagopal A, Penn JS. In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced Retinopathy. Sci Rep. 2016 Aug 8/5/2016; 6: 31011. PMID: 27491345, PMCID: PMC4974503, PII: srep31011, DOI: 10.1038/srep31011, ISSN: 2045-2322.

Gahlaut N, Suarez S, Uddin MI, Gordon AY, Evans SM, Jayagopal A. Nanoengineering of therapeutics for retinal vascular disease. Eur J Pharm Biopharm [print-electronic]. 2015 Sep; 95(Pt B): 323-30. PMID: 26022642, PMCID: PMC4604030, PII: S0939-6411(15)00219-2, DOI: 10.1016/j.ejpb.2015.05.001, ISSN: 1873-3441.

Uddin MI, Evans SM, Craft JR, Marnett LJ, Uddin MJ, Jayagopal A. Applications of azo-based probes for imaging retinal hypoxia. ACS Med Chem Lett. 2015 Apr 4/9/2015; 6(4): 445-9. PMID: 25893047, PMCID: PMC4394343, DOI: 10.1021/ml5005206.

Evans SM, Kim K, Moore CE, Uddin MI, Capozzi ME, Craft JR, Sulikowski GA, Jayagopal A. Molecular probes for imaging of hypoxia in the retina. Bioconjug. Chem [print-electronic]. 2014 Nov 11/19/2014; 25(11): 2030-7. PMID: 25250692, PMCID: PMC4240343, DOI: 10.1021/bc500400z, ISSN: 1520-4812.

Uddin MI, Buck JR, Schulte ML, Tang D, Saleh SA, Cheung YY, Harp J, Manning HC. Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes. Tetrahedron Lett. 2014 Jan 1/1/2014; 55(1): PMID: 24396154, PMCID: PMC3880151, DOI: 10.1016/j.tetlet.2013.10.143, ISSN: 0040-4039.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC. Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging. J. Med. Chem [print-electronic]. 2013 Apr 4/25/2013; 56(8): 3429-33. PMID: 23521048, PMCID: PMC3648642, DOI: 10.1021/jm4001874, ISSN: 1520-4804.

McKinley ET, Smith RA, Zhao P, Fu A, Saleh SA, Uddin MI, Washington MK, Coffey RJ, Manning HC. 3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer. J. Nucl. Med [print-electronic]. 2013 Mar; 54(3): 424-30. PMID: 23341544, PMCID: PMC3633462, PII: jnumed.112.108456, DOI: 10.2967/jnumed.112.108456, ISSN: 1535-5667.

Buck JR, Saleh S, Uddin MI, Manning HC. Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research. Tetrahedron Lett [print-electronic]. 2012 Aug 8/8/2012; 53(32): 4161-5. PMID: 23180892, PMCID: PMC3501741, DOI: 10.1016/j.tetlet.2012.05.137, ISSN: 0040-4039.