Sarika Saraswati, Ph.D.

Research Assistant Professor

sarika.saraswati@vanderbilt.edu
Faculty Appointments
Research Assistant Professor of Pathology, Microbiology and Immunology
Education
Ph.D., Biochemistry and Molecular Bioplogy, University of Arkansas, Little Rock, ArkansasM.S., Botany, University of Allahabad, Allahabad, IndiaB.S., Biological Sciences, University of Allahabad, Allahabad, India
Publications
Bastakoty D, Saraswati S, Joshi P, Atkinson J, Feoktistov I, Liu J, Harris JL, Young PP. Temporary, Systemic Inhibition of the WNT/ß-Catenin Pathway promotes Regenerative Cardiac Repair following Myocardial Infarct. Cell Stem Cells Regen Med [print-electronic]. 2016 Nov; 2(2): PMID: 28042617, PMCID: PMC5193163, ISSN: 2472-6990.

Bastakoty D, Saraswati S, Cates J, Lee E, Nanney LB, Young PP. Inhibition of Wnt/ß-catenin pathway promotes regenerative repair of cutaneous and cartilage injury. FASEB J [print-electronic]. 2015 Dec; 29(12): 4881-92. PMID: 26268926, PMCID: PMC4653050, PII: fj.15-275941, DOI: 10.1096/fj.15-275941, ISSN: 1530-6860.

Saraswati S, Guo Y, Atkinson J, Young PP. Prolonged hypoxia induces monocarboxylate transporter-4 expression in mesenchymal stem cells resulting in a secretome that is deleterious to cardiovascular repair. Stem Cells. 2015 Apr; 33(4): 1333-44. PMID: 25537659, PMCID: PMC4376598, DOI: 10.1002/stem.1935, ISSN: 1549-4918.

Deskins DL, Bastakoty D, Saraswati S, Shinar A, Holt GE, Young PP. Human mesenchymal stromal cells: identifying assays to predict potency for therapeutic selection. Stem Cells Transl Med [print-electronic]. 2013 Feb; 2(2): 151-8. PMID: 23362238, PMCID: PMC3659751, PII: sctm.2012-0099, DOI: 10.5966/sctm.2012-0099, ISSN: 2157-6564.

Saraswati S, Deskins DL, Holt GE, Young PP. Pyrvinium, a potent small molecule Wnt inhibitor, increases engraftment and inhibits lineage commitment of mesenchymal stem cells (MSCs). Wound Repair Regen [print-electronic]. 2012 Mar; 20(2): 185-93. PMID: 22332749, PMCID: PMC3303160, DOI: 10.1111/j.1524-475X.2012.00767.x, ISSN: 1524-475X.

Alfaro MP, Saraswati S, Young PP. Molecular mediators of mesenchymal stem cell biology. Vitam. Horm. 2011; 87: 39-59. PMID: 22127236, PMCID: PMC5766260, PII: B978-0-12-386015-6.00023-8, DOI: 10.1016/B978-0-12-386015-6.00023-8, ISSN: 0083-6729.

Saraswati S, Alfaro MP, Thorne CA, Atkinson J, Lee E, Young PP. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling. PLoS ONE. 2010 Nov 11/29/2010; 5(11): e15521. PMID: 21170416, PMCID: PMC2993965, DOI: 10.1371/journal.pone.0015521, ISSN: 1932-6203.

Alfaro MP, Vincent A, Saraswati S, Thorne CA, Hong CC, Lee E, Young PP. SFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair. J. Biol. Chem [print-electronic]. 2010 Nov 11/12/2010; 285(46): 35645-53. PMID: 20826809, PMCID: PMC2975189, PII: M110.135335, DOI: 10.1074/jbc.M110.135335, ISSN: 1083-351X.