Krystle A. Lang Kuhs, Ph.D.

Assistant Professor

krystle.kuhs@vanderbilt.edu
Faculty Appointments
Assistant Professor of Medicine Assistant Professor of Otolaryngology
Education
M.P.H., Epidemiology and Biostatistics, Johns Hopkins University, Baltimore, MarylandPh.D., Pharmacology, University of Pennsylvania, Philadelphia, PennsylvaniaB.S., Biology, University of Rhode Island, Kingston, Rhode Island
Office Address
2525 West End Ave
Suite 800
Nashville, TN 37203
Publications
Lang Kuhs KA, Pawlita M, Gibson SP, Schmitt NC, Trivedi S, Argiris A, Kreimer AR, Ferris RL, Waterboer T. Characterization of human papillomavirus antibodies in individuals with head and neck cancer. Cancer Epidemiol [print-electronic]. 2016 Jun; 42: 46-52. PMID: 27010729, PMCID: PMC4910878, PII: S1877-7821(16)30028-5, DOI: 10.1016/j.canep.2016.03.003, ISSN: 1877-783X.

Finnberg NK, Gokare P, Navaraj A, Lang Kuhs KA, Cerniglia G, Yagita H, Takeda K, Motoyama N, El-Deiry WS. Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity. Cancer Res [print-electronic]. 2016 Feb 2/1/2016; 76(3): 700-12. PMID: 26609054, PII: 0008-5472.CAN-15-2759, DOI: 10.1158/0008-5472.CAN-15-2759, ISSN: 1538-7445.

O'Brien TR, Pfeiffer RM, Paquin A, Lang Kuhs KA, Chen S, Bonkovsky HL, Edlin BR, Howell CD, Kirk GD, Kuniholm MH, Morgan TR, Strickler HD, Thomas DL, Prokunina-Olsson L. Comparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance. J. Hepatol [print-electronic]. 2015 Nov; 63(5): 1103-10. PMID: 26186989, PMCID: PMC4615534, PII: S0168-8278(15)00465-1, DOI: 10.1016/j.jhep.2015.06.035, ISSN: 1600-0641.

Lang Kuhs KA, Hildesheim A, Trabert B, Kemp TJ, Purdue MP, Wentzensen N, Katki HA, Pinto LA, Loftfield E, Safaeian M, Chaturvedi AK, Shiels MS. Association between Regular Aspirin Use and Circulating Markers of Inflammation: A Study within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2015 May; 24(5): 825-32. PMID: 25713025, PMCID: PMC4417370, PII: 1055-9965.EPI-14-1363, DOI: 10.1158/1055-9965.EPI-14-1363, ISSN: 1538-7755.

Lang Kuhs KA, Anantharaman D, Waterboer T, Johansson M, Brennan P, Michel A, Willhauck-Fleckenstein M, Purdue MP, Holcátová I, Ahrens W, Lagiou P, Polesel J, Simonato L, Merletti F, Healy CM, Kjaerheim K, Conway DI, Macfarlane TV, Thomson P, Castellsagué X, Znaor A, Black A, Huang WY, Krogh V, Trichopoulou A, Bueno-de-Mesquita HB, Clavel-Chapelon F, Weiderpass E, Ekström J, Riboli E, Tjønneland A, Sánchez MJ, Travis RC, Hildesheim A, Pawlita M, Kreimer AR. Human Papillomavirus 16 E6 Antibodies in Individuals without Diagnosed Cancer: A Pooled Analysis. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2015 Apr; 24(4): 683-9. PMID: 25623733, PMCID: PMC4383678, PII: 1055-9965.EPI-14-1217, DOI: 10.1158/1055-9965.EPI-14-1217, ISSN: 1538-7755.

Kreimer AR, Brennan P, Lang Kuhs KA, Waterboer T, Clifford G, Franceschi S, Michel A, Willhauck-Fleckenstein M, Riboli E, Castellsagué X, Hildesheim A, Fortner RT, Kaaks R, Palli D, Ljuslinder I, Panico S, Clavel-Chapelon F, Boutron-Ruault MC, Mesrine S, Trichopoulou A, Lagiou P, Trichopoulos D, Peeters PH, Cross AJ, Bueno-de-Mesquita HB, Vineis P, Larrañaga N, Pala V, Sánchez MJ, Navarro C, Barricarte A, Tumino R, Khaw KT, Wareham N, Boeing H, Steffen A, Travis RC, Quirós JR, Weiderpass E, Pawlita M, Johansson M. Human papillomavirus antibodies and future risk of anogenital cancer: a nested case-control study in the European prospective investigation into cancer and nutrition study. J. Clin. Oncol [print-electronic]. 2015 Mar 3/10/2015; 33(8): 877-84. PMID: 25667279, PMCID: PMC4348636, PII: JCO.2014.57.8435, DOI: 10.1200/JCO.2014.57.8435, ISSN: 1527-7755.

Lang Kuhs KA, Kuniholm MH, Pfeiffer RM, Chen S, Desai S, Edlin BR, Peters MG, Plankey M, Sharp GB, Strickler HD, Villacres MC, Quinn TC, Gange SJ, Prokunina-Olsson L, Greenblatt RM, O'Brien TR. Interferon Lambda 4 Genotype Is Not Associated with Recurrence of Oral or Genital Herpes. PLoS ONE. 2015; 10(10): e0138827. PMID: 26431156, PMCID: PMC4592222, PII: PONE-D-15-15666, DOI: 10.1371/journal.pone.0138827, ISSN: 1932-6203.

Lang Kuhs KA, Gonzalez P, Rodriguez AC, van Doorn LJ, Schiffman M, Struijk L, Chen S, Quint W, Lowy DR, Porras C, DelVecchio C, Jimenez S, Safaeian M, Schiller JT, Wacholder S, Herrero R, Hildesheim A, Kreimer AR, . Reduced prevalence of vulvar HPV16/18 infection among women who received the HPV16/18 bivalent vaccine: a nested analysis within the Costa Rica Vaccine Trial. J. Infect. Dis [print-electronic]. 2014 Dec 12/15/2014; 210(12): 1890-9. PMID: 24958910, PMCID: PMC4271025, PII: jiu357, DOI: 10.1093/infdis/jiu357, ISSN: 1537-6613.

O'Brien TR, Lang Kuhs KA, Pfeiffer RM. Subgroup differences in response to 8 weeks of ledipasvir/sofosbuvir for chronic hepatitis C. Open Forum Infect Dis. 2014 Dec; 1(3): ofu110. PMID: 25734178, PMCID: PMC4324232, PII: ofu110, DOI: 10.1093/ofid/ofu110, ISSN: 2328-8957.

Lang Kuhs KA, Porras C, Schiller JT, Rodriguez AC, Schiffman M, Gonzalez P, Wacholder S, Ghosh A, Li Y, Lowy DR, Kreimer AR, Poncelet S, Schussler J, Quint W, van Doorn LJ, Sherman ME, Sidawy M, Herrero R, Hildesheim A, Safaeian M, . Effect of different human papillomavirus serological and DNA criteria on vaccine efficacy estimates. Am. J. Epidemiol [print-electronic]. 2014 Sep 9/15/2014; 180(6): 599-607. PMID: 25139208, PMCID: PMC4157699, PII: kwu168, DOI: 10.1093/aje/kwu168, ISSN: 1476-6256.

Lang Kuhs KA, Gonzalez P, Struijk L, Castro F, Hildesheim A, van Doorn LJ, Rodriguez AC, Schiffman M, Quint W, Lowy DR, Porras C, Delvecchio C, Katki HA, Jimenez S, Safaeian M, Schiller J, Solomon D, Wacholder S, Herrero R, Kreimer AR, . Prevalence of and risk factors for oral human papillomavirus among young women in Costa Rica. J. Infect. Dis [print-electronic]. 2013 Nov 11/15/2013; 208(10): 1643-52. PMID: 24014882, PMCID: PMC3805238, PII: jit369, DOI: 10.1093/infdis/jit369, ISSN: 1537-6613.

Lang Kuhs KA, Ginsberg AA, Yan J, Wiseman RW, Khan AS, Sardesai NY, O'Connor DH, Weiner DB. Hepatitis C virus NS3/NS4A DNA vaccine induces multiepitope T cell responses in rhesus macaques mimicking human immune responses [corrected]. Mol. Ther [print-electronic]. 2012 Mar; 20(3): 669-78. PMID: 21952169, PMCID: PMC3293616, PII: mt2011188, DOI: 10.1038/mt.2011.188, ISSN: 1525-0024.

Lang Kuhs KA, Toporovski R, Yan J, Ginsberg AA, Shedlock DJ, Weiner DB. Induction of intrahepatic HCV NS4B, NS5A and NS5B-specific cellular immune responses following peripheral immunization. PLoS ONE [print-electronic]. 2012; 7(12): e52165. PMID: 23284919, PMCID: PMC3528776, PII: PONE-D-12-24679, DOI: 10.1371/journal.pone.0052165, ISSN: 1932-6203.

Kang DW, Kim YS, Lim KS, Kim MS, Pearce LV, Pavlyukovets VA, Tao AK, Lang-Kuhs KA, Blumberg PM, Lee J. Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicin. Bioorg. Med. Chem [print-electronic]. 2010 Nov 11/15/2010; 18(22): 8092-105. PMID: 20937561, PMCID: PMC3420354, PII: S0968-0896(10)00816-3, DOI: 10.1016/j.bmc.2010.09.001, ISSN: 1464-3391.

Lang KA, Yan J, Draghia-Akli R, Khan A, Weiner DB. Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Vaccine [print-electronic]. 2008 Nov 11/18/2008; 26(49): 6225-31. PMID: 18692108, PMCID: PMC4477808, PII: S0264-410X(08)00954-7, DOI: 10.1016/j.vaccine.2008.07.052, ISSN: 0264-410X.

Lang K, Weiner DB. Immunotherapy for HCV infection: next steps. Expert Rev Vaccines. 2008 Sep; 7(7): 915-23. PMID: 18767942, DOI: 10.1586/14760584.7.7.915, ISSN: 1744-8395.