Faculty Appointments
Associate Professor of Anesthesiology
Associate Professor of Biomedical Informatics
Education
M.D., Baylor College of Medicine, Houston, TexasM.S., Biotechnology, Johns Hopkins University, Baltimore, MarylandB.A., German Literature, Johns Hopkins University, Baltimore, Maryland
Publications
Bellomy ML, Freundlich RE. Hyperglycemia and Elevated Lactate in Trauma: Where Do We Go From Here?. Anesth. Analg. 2018 Mar; 126(3): 748-9. PMID: 29461323, PII: 00000539-201803000-00009, DOI: 10.1213/ANE.0000000000002757, ISSN: 1526-7598.
Freundlich RE, Lopez MG, Kingeter AJ. Not All Calcium Formulations Are Alike. Anesth. Analg. 2018 Feb; 126(2): 728. PMID: 29189270, DOI: 10.1213/ANE.0000000000002651, ISSN: 1526-7598.
Freundlich RE, Maile MD, Sferra JJ, Jewell ES, Kheterpal S, Engoren M. Complications Associated With Mortality in the National Surgical Quality Improvement Program Database. Anesth. Analg [print-electronic]. 2018 Jan 1/9/2018; PMID: 29324497, DOI: 10.1213/ANE.0000000000002799, ISSN: 1526-7598.
Freundlich RE, Ehrenfeld JM. Anesthesia information management: clinical decision support. Curr Opin Anaesthesiol. 2017 Dec; 30(6): 705-9. PMID: 28938302, DOI: 10.1097/ACO.0000000000000526, ISSN: 1473-6500.
Freundlich RE, Freundlich KL, Drolet BC. Pagers, Smartphones, and HIPAA: Finding the Best Solution for Electronic Communication of Protected Health Information. J Med Syst. 2017 Nov 11/25/2017; 42(1): 9. PMID: 29177600, PII: 10.1007/s10916-017-0870-9, DOI: 10.1007/s10916-017-0870-9, ISSN: 1573-689X.
Freundlich RE, Ehrenfeld JM. Perioperative Information Systems: Opportunities to Improve Delivery of Care and Clinical Outcomes in Cardiac and Vascular Surgery. J. Cardiothorac. Vasc. Anesth [print-electronic]. 2017 Nov 11/4/2017; PMID: 29229258, PII: S1053-0770(17)30880-7, DOI: 10.1053/j.jvca.2017.11.002, ISSN: 1532-8422.
Freundlich RE, Kingeter AJ. When Managing Patients with Left Ventricular Assist Devices Undergoing Noncardiac Surgery, Less Is Not More [letter]. Anesthesiology. 2017 Nov; 127(5): 901-2. PMID: 29040105, PII: 00000542-201711000-00040, DOI: 10.1097/ALN.0000000000001852, ISSN: 1528-1175.
Berman MF, Iyer N, Freudzon L, Wang S, Freundlich RE, Housey M, Kheterpal S, . Alarm Limits for Intraoperative Drug Infusions: A Report From the Multicenter Perioperative Outcomes Group. Anesth. Analg. 2017 Oct; 125(4): 1203-11. PMID: 28759483, DOI: 10.1213/ANE.0000000000002305, ISSN: 1526-7598.
Kruger GH, Shanks A, Kheterpal S, Tremper T, Chiang CJ, Freundlich RE, Blum JM, Shih AJ, Tremper KK. Influence of non-invasive blood pressure measurement intervals on the occurrence of intra-operative hypotension. J Clin Monit Comput [print-electronic]. 2017 Sep 9/30/2017; PMID: 28965158, PII: 10.1007/s10877-017-0065-4, DOI: 10.1007/s10877-017-0065-4, ISSN: 1573-2614.
Kiefer J, Freundlich RE. Confounding variables impacting the association between duration of veno-arterial extracorporeal life support and mortality [letter]. Crit Care. 2017 Aug 8/1/2017; 21(1): 203. PMID: 28764805, PMCID: PMC5539615, PII: 10.1186/s13054-017-1773-3, DOI: 10.1186/s13054-017-1773-3, ISSN: 1466-609X.
Freundlich RE, Ehrenfeld JM. Quality metrics: hard to develop, hard to validate. Br J Anaesth. 2017 Jul 7/1/2017; 119(1): 10-1. PMID: 28974060, PII: S0007-0912(17)33730-3, DOI: 10.1093/bja/aex084, ISSN: 1471-6771.
Freundlich RE, Maile MD, Hajjar MM, Habib JR, Jewell ES, Schwann T, Habib RH, Engoren M. Years of Life Lost After Complications of Coronary Artery Bypass Operations. Ann. Thorac. Surg [print-electronic]. 2017 Jun; 103(6): 1893-9. PMID: 27938887, PII: S0003-4975(16)31300-5, DOI: 10.1016/j.athoracsur.2016.09.048, ISSN: 1552-6259.
Freundlich RE, Wanderer JP, Ehrenfeld JM. Building Big Datasets: Do Not Forget the EMR [letter]. Anesth. Analg. 2017 Apr; 124(4): 1367. PMID: 28212218, DOI: 10.1213/ANE.0000000000001809, ISSN: 1526-7598.
Freundlich RE, Duggal NM, Housey M, Tremper TT, Engoren MC, Kheterpal S. Intraoperative medications associated with hemodynamically significant anaphylaxis. J Clin Anesth [print-electronic]. 2016 Dec; 35: 415-23. PMID: 27871567, PII: S0952-8180(16)30716-4, DOI: 10.1016/j.jclinane.2016.09.023, ISSN: 1873-4529.
Joseph JR, Freundlich RE, Abir M. Ruptured subcapsular liver haematoma following mechanically-assisted cardiopulmonary resuscitation. BMJ Case Rep. 2016 Feb 2/2/2016; 2016: PMID: 26838302, PMCID: PMC4746549, PII: bcr-2015-213951, DOI: 10.1136/bcr-2015-213951, ISSN: 1757-790X.
Freundlich RE, Newman JW, Tremper KK, Mhyre JM, Kheterpal S, Sanford TJ, Tait AR. The impact of a dedicated research education month for anesthesiology residents. Anesthesiol Res Pract [print-electronic]. 2015; 2015: 623959. PMID: 25653678, PMCID: PMC4309211, DOI: 10.1155/2015/623959, ISSN: 1687-6962.
Mathis MR, Naughton NN, Shanks AM, Freundlich RE, Pannucci CJ, Chu Y, Haus J, Morris M, Kheterpal S. Patient selection for day case-eligible surgery: identifying those at high risk for major complications. Anesthesiology. 2013 Dec; 119(6): 1310-21. PMID: 24108100, DOI: 10.1097/ALN.0000000000000005, ISSN: 1528-1175.
Kheterpal S, Healy D, Aziz MF, Shanks AM, Freundlich RE, Linton F, Martin LD, Linton J, Epps JL, Fernandez-Bustamante A, Jameson LC, Tremper T, Tremper KK, . Incidence, predictors, and outcome of difficult mask ventilation combined with difficult laryngoscopy: a report from the multicenter perioperative outcomes group. Anesthesiology. 2013 Dec; 119(6): 1360-9. PMID: 24071617, DOI: 10.1097/ALN.0000435832.39353.20, ISSN: 1528-1175.
Mashour GA, Sharifpour M, Freundlich RE, Tremper KK, Shanks A, Nallamothu BK, Vlisides PE, Weightman A, Matlen L, Merte J, Kheterpal S. Perioperative metoprolol and risk of stroke after noncardiac surgery. Anesthesiology. 2013 Dec; 119(6): 1340-6. PMID: 23612244, DOI: 10.1097/ALN.0b013e318295a25f, ISSN: 1528-1175.
Freundlich RE, Barnet CS, Mathis MR, Shanks AM, Tremper KK, Kheterpal S. A randomized trial of automated electronic alerts demonstrating improved reimbursable anesthesia time documentation. J Clin Anesth [print-electronic]. 2013 Mar; 25(2): 110-4. PMID: 23333782, PII: S0952-8180(12)00416-3, DOI: 10.1016/j.jclinane.2012.06.020, ISSN: 1873-4529.
Freundlich RE, Grondin L, Tremper KK, Saran KA, Kheterpal S. Automated electronic reminders to prevent miscommunication among primary medical, surgical and anaesthesia providers: a root cause analysis. BMJ Qual Saf [print-electronic]. 2012 Oct; 21(10): 850-4. PMID: 22773892, PII: bmjqs-2011-000666, DOI: 10.1136/bmjqs-2011-000666, ISSN: 2044-5423.
Moskovic DJ, Freundlich RE, Yazdani P, Lipshultz LI, Khera M. Subcutaneous implantable testosterone pellets overcome noncompliance in adolescents with Klinefelter syndrome. J. Androl [print-electronic]. 2012 Jul; 33(4): 570-3. PMID: 21940986, PII: jandrol.111.013979, DOI: 10.2164/jandrol.111.013979, ISSN: 1939-4640.
Freundlich RE, Kheterpal S. Perioperative effectiveness research using large databases. Best Pract Res Clin Anaesthesiol. 2011 Dec; 25(4): 489-98. PMID: 22099915, PII: S1521-6896(11)00081-4, DOI: 10.1016/j.bpa.2011.08.008, ISSN: 1521-6896.
Freundlich RE, Hawes LT, Weldon SA, Brunicardi FC. Laparoscopic repair of an incarcerated right indirect sliding inguinal hernia involving a retroperitoneal ileum. Hernia [print-electronic]. 2011 Apr; 15(2): 225-7. PMID: 20165969, DOI: 10.1007/s10029-010-0638-3, ISSN: 1248-9204.
Mohamed O, Freundlich RE, Dakik HK, Grober ED, Najari B, Lipshultz LI, Khera M. The quantitative ADAM questionnaire: a new tool in quantifying the severity of hypogonadism. Int. J. Impot. Res [print-electronic]. 2010 Jan; 22(1): 20-4. PMID: 19657348, PMCID: PMC2834355, PII: ijir200935, DOI: 10.1038/ijir.2009.35, ISSN: 1476-5489.
Marton A, Clark CC, Srinivasan R, Freundlich RE, Narducci Sarjeant AA, Meyer GJ. Static and dynamic quenching of Ru(II) polypyridyl excited states by iodide. Inorg Chem. 2006 Jan 1/9/2006; 45(1): 362-9. PMID: 16390077, DOI: 10.1021/ic051467j, ISSN: 0020-1669.
Freundlich RE, Lopez MG, Kingeter AJ. Not All Calcium Formulations Are Alike. Anesth. Analg. 2018 Feb; 126(2): 728. PMID: 29189270, DOI: 10.1213/ANE.0000000000002651, ISSN: 1526-7598.
Freundlich RE, Maile MD, Sferra JJ, Jewell ES, Kheterpal S, Engoren M. Complications Associated With Mortality in the National Surgical Quality Improvement Program Database. Anesth. Analg [print-electronic]. 2018 Jan 1/9/2018; PMID: 29324497, DOI: 10.1213/ANE.0000000000002799, ISSN: 1526-7598.
Freundlich RE, Ehrenfeld JM. Anesthesia information management: clinical decision support. Curr Opin Anaesthesiol. 2017 Dec; 30(6): 705-9. PMID: 28938302, DOI: 10.1097/ACO.0000000000000526, ISSN: 1473-6500.
Freundlich RE, Freundlich KL, Drolet BC. Pagers, Smartphones, and HIPAA: Finding the Best Solution for Electronic Communication of Protected Health Information. J Med Syst. 2017 Nov 11/25/2017; 42(1): 9. PMID: 29177600, PII: 10.1007/s10916-017-0870-9, DOI: 10.1007/s10916-017-0870-9, ISSN: 1573-689X.
Freundlich RE, Ehrenfeld JM. Perioperative Information Systems: Opportunities to Improve Delivery of Care and Clinical Outcomes in Cardiac and Vascular Surgery. J. Cardiothorac. Vasc. Anesth [print-electronic]. 2017 Nov 11/4/2017; PMID: 29229258, PII: S1053-0770(17)30880-7, DOI: 10.1053/j.jvca.2017.11.002, ISSN: 1532-8422.
Freundlich RE, Kingeter AJ. When Managing Patients with Left Ventricular Assist Devices Undergoing Noncardiac Surgery, Less Is Not More [letter]. Anesthesiology. 2017 Nov; 127(5): 901-2. PMID: 29040105, PII: 00000542-201711000-00040, DOI: 10.1097/ALN.0000000000001852, ISSN: 1528-1175.
Berman MF, Iyer N, Freudzon L, Wang S, Freundlich RE, Housey M, Kheterpal S, . Alarm Limits for Intraoperative Drug Infusions: A Report From the Multicenter Perioperative Outcomes Group. Anesth. Analg. 2017 Oct; 125(4): 1203-11. PMID: 28759483, DOI: 10.1213/ANE.0000000000002305, ISSN: 1526-7598.
Kruger GH, Shanks A, Kheterpal S, Tremper T, Chiang CJ, Freundlich RE, Blum JM, Shih AJ, Tremper KK. Influence of non-invasive blood pressure measurement intervals on the occurrence of intra-operative hypotension. J Clin Monit Comput [print-electronic]. 2017 Sep 9/30/2017; PMID: 28965158, PII: 10.1007/s10877-017-0065-4, DOI: 10.1007/s10877-017-0065-4, ISSN: 1573-2614.
Kiefer J, Freundlich RE. Confounding variables impacting the association between duration of veno-arterial extracorporeal life support and mortality [letter]. Crit Care. 2017 Aug 8/1/2017; 21(1): 203. PMID: 28764805, PMCID: PMC5539615, PII: 10.1186/s13054-017-1773-3, DOI: 10.1186/s13054-017-1773-3, ISSN: 1466-609X.
Freundlich RE, Ehrenfeld JM. Quality metrics: hard to develop, hard to validate. Br J Anaesth. 2017 Jul 7/1/2017; 119(1): 10-1. PMID: 28974060, PII: S0007-0912(17)33730-3, DOI: 10.1093/bja/aex084, ISSN: 1471-6771.
Freundlich RE, Maile MD, Hajjar MM, Habib JR, Jewell ES, Schwann T, Habib RH, Engoren M. Years of Life Lost After Complications of Coronary Artery Bypass Operations. Ann. Thorac. Surg [print-electronic]. 2017 Jun; 103(6): 1893-9. PMID: 27938887, PII: S0003-4975(16)31300-5, DOI: 10.1016/j.athoracsur.2016.09.048, ISSN: 1552-6259.
Freundlich RE, Wanderer JP, Ehrenfeld JM. Building Big Datasets: Do Not Forget the EMR [letter]. Anesth. Analg. 2017 Apr; 124(4): 1367. PMID: 28212218, DOI: 10.1213/ANE.0000000000001809, ISSN: 1526-7598.
Freundlich RE, Duggal NM, Housey M, Tremper TT, Engoren MC, Kheterpal S. Intraoperative medications associated with hemodynamically significant anaphylaxis. J Clin Anesth [print-electronic]. 2016 Dec; 35: 415-23. PMID: 27871567, PII: S0952-8180(16)30716-4, DOI: 10.1016/j.jclinane.2016.09.023, ISSN: 1873-4529.
Joseph JR, Freundlich RE, Abir M. Ruptured subcapsular liver haematoma following mechanically-assisted cardiopulmonary resuscitation. BMJ Case Rep. 2016 Feb 2/2/2016; 2016: PMID: 26838302, PMCID: PMC4746549, PII: bcr-2015-213951, DOI: 10.1136/bcr-2015-213951, ISSN: 1757-790X.
Freundlich RE, Newman JW, Tremper KK, Mhyre JM, Kheterpal S, Sanford TJ, Tait AR. The impact of a dedicated research education month for anesthesiology residents. Anesthesiol Res Pract [print-electronic]. 2015; 2015: 623959. PMID: 25653678, PMCID: PMC4309211, DOI: 10.1155/2015/623959, ISSN: 1687-6962.
Mathis MR, Naughton NN, Shanks AM, Freundlich RE, Pannucci CJ, Chu Y, Haus J, Morris M, Kheterpal S. Patient selection for day case-eligible surgery: identifying those at high risk for major complications. Anesthesiology. 2013 Dec; 119(6): 1310-21. PMID: 24108100, DOI: 10.1097/ALN.0000000000000005, ISSN: 1528-1175.
Kheterpal S, Healy D, Aziz MF, Shanks AM, Freundlich RE, Linton F, Martin LD, Linton J, Epps JL, Fernandez-Bustamante A, Jameson LC, Tremper T, Tremper KK, . Incidence, predictors, and outcome of difficult mask ventilation combined with difficult laryngoscopy: a report from the multicenter perioperative outcomes group. Anesthesiology. 2013 Dec; 119(6): 1360-9. PMID: 24071617, DOI: 10.1097/ALN.0000435832.39353.20, ISSN: 1528-1175.
Mashour GA, Sharifpour M, Freundlich RE, Tremper KK, Shanks A, Nallamothu BK, Vlisides PE, Weightman A, Matlen L, Merte J, Kheterpal S. Perioperative metoprolol and risk of stroke after noncardiac surgery. Anesthesiology. 2013 Dec; 119(6): 1340-6. PMID: 23612244, DOI: 10.1097/ALN.0b013e318295a25f, ISSN: 1528-1175.
Freundlich RE, Barnet CS, Mathis MR, Shanks AM, Tremper KK, Kheterpal S. A randomized trial of automated electronic alerts demonstrating improved reimbursable anesthesia time documentation. J Clin Anesth [print-electronic]. 2013 Mar; 25(2): 110-4. PMID: 23333782, PII: S0952-8180(12)00416-3, DOI: 10.1016/j.jclinane.2012.06.020, ISSN: 1873-4529.
Freundlich RE, Grondin L, Tremper KK, Saran KA, Kheterpal S. Automated electronic reminders to prevent miscommunication among primary medical, surgical and anaesthesia providers: a root cause analysis. BMJ Qual Saf [print-electronic]. 2012 Oct; 21(10): 850-4. PMID: 22773892, PII: bmjqs-2011-000666, DOI: 10.1136/bmjqs-2011-000666, ISSN: 2044-5423.
Moskovic DJ, Freundlich RE, Yazdani P, Lipshultz LI, Khera M. Subcutaneous implantable testosterone pellets overcome noncompliance in adolescents with Klinefelter syndrome. J. Androl [print-electronic]. 2012 Jul; 33(4): 570-3. PMID: 21940986, PII: jandrol.111.013979, DOI: 10.2164/jandrol.111.013979, ISSN: 1939-4640.
Freundlich RE, Kheterpal S. Perioperative effectiveness research using large databases. Best Pract Res Clin Anaesthesiol. 2011 Dec; 25(4): 489-98. PMID: 22099915, PII: S1521-6896(11)00081-4, DOI: 10.1016/j.bpa.2011.08.008, ISSN: 1521-6896.
Freundlich RE, Hawes LT, Weldon SA, Brunicardi FC. Laparoscopic repair of an incarcerated right indirect sliding inguinal hernia involving a retroperitoneal ileum. Hernia [print-electronic]. 2011 Apr; 15(2): 225-7. PMID: 20165969, DOI: 10.1007/s10029-010-0638-3, ISSN: 1248-9204.
Mohamed O, Freundlich RE, Dakik HK, Grober ED, Najari B, Lipshultz LI, Khera M. The quantitative ADAM questionnaire: a new tool in quantifying the severity of hypogonadism. Int. J. Impot. Res [print-electronic]. 2010 Jan; 22(1): 20-4. PMID: 19657348, PMCID: PMC2834355, PII: ijir200935, DOI: 10.1038/ijir.2009.35, ISSN: 1476-5489.
Marton A, Clark CC, Srinivasan R, Freundlich RE, Narducci Sarjeant AA, Meyer GJ. Static and dynamic quenching of Ru(II) polypyridyl excited states by iodide. Inorg Chem. 2006 Jan 1/9/2006; 45(1): 362-9. PMID: 16390077, DOI: 10.1021/ic051467j, ISSN: 0020-1669.