Staci L. Sudenga, Ph.D.

Assistant Professor
Faculty Appointments
Assistant Professor of Medicine
Ph.D., Epidemiology, University of Alabama, Birmingham, AlabamaM.P.H., Epidemiology, University of Alabama, Birmingham, AlabamaB.A., Biology, Luther College, Decorah, Iowa
Research Description
My research program focuses on infections and cancer, the natural history of infections, and the synergy between infections. The goal of my research is to identify modifiable factors associated with the acquisition of infection in order to increase primary prevention and to identify biologically meaningful associations between the host and pathogen that could be translated into primary prevention efforts, early diagnosis, or treatment.
Research Keywords
Epidemiology, HPV, HIV, Cancer
Castilho JL, Bian A, Jenkins CA, Shepherd BE, Sigel K, Gill MJ, Kitahata MM, Silverberg MJ, Mayor AM, Coburn SB, Wiley D, Achenbach CJ, Marconi VC, Bosch RJ, Horberg MA, Rabkin CS, Napravnik S, Novak RM, Mathews WC, Thorne JE, Sun J, Althoff KN, Moore RD, Sterling TR, Sudenga SL, . CD4/CD8 Ratio and Cancer Risk among Adults with HIV. J Natl Cancer Inst [print-electronic]. 2022 Mar 3/16/2022; PMID: 35292820, PII: 6548163, DOI: 10.1093/jnci/djac053, ISSN: 1460-2105.

Shing JZ, Griffin MR, Chang RS, Beeghly-Fadiel A, Sudenga SL, Slaughter JC, Pemmaraju M, Mitchel EF, Hull PC. Human Papillomavirus Vaccine Impact on Cervical Precancers in a Low-Vaccination Population. Am J Prev Med [print-electronic]. 2022 Mar; 62(3): 395-403. PMID: 34756753, PMCID: PMC8863582, PII: S0749-3797(21)00497-9, DOI: 10.1016/j.amepre.2021.08.017, ISSN: 1873-2607.

Sudenga SL, Lotspeich SC, Nyitray AG, Sirak B, Shepherd BE, Messina J, Sereday KA, Silva RC, Abrahamsen M, Baggio ML, Quiterio M, Lazcano-Ponce E, Villa L, Giuliano AR. The Role of External Genital Lesions in Human Immunodeficiency Virus Seroconversion Among Men Participating in a Multinational Study. Sex Transm Dis. 2022 Jan 1/1/2022; 49(1): 55-8. PMID: 34282740, PMCID: PMC8722569, PII: 00007435-900000000-97615, DOI: 10.1097/OLQ.0000000000001516, ISSN: 1537-4521.

Shing JZ, Beeghly-Fadiel A, Griffin MR, Chang RS, Sudenga SL, Slaughter JC, Pemmaraju M, Mitchel EF, Hull PC. The Impact of the Human Papillomavirus Vaccine on High-Grade Cervical Lesions in Urban and Rural Areas: An Age-Period-Cohort Analysis. Cancers (Basel). 2021 Aug 8/21/2021; 13(16): PMID: 34439369, PMCID: PMC8391543, PII: cancers13164215, DOI: 10.3390/cancers13164215, ISSN: 2072-6694.

Muhimpundu S, Conway RBN, Warren Andersen S, Lipworth L, Steinwandel MD, Blot WJ, Shu XO, Sudenga SL. Racial Differences in Hepatocellular Carcinoma Incidence and Risk Factors among a Low Socioeconomic Population. Cancers (Basel). 2021 Jul 7/23/2021; 13(15): PMID: 34359611, PMCID: PMC8345125, PII: cancers13153710, DOI: 10.3390/cancers13153710, ISSN: 2072-6694.

Ye Y, Burkholder GA, Mukherjee A, Chu D, Bansal A, Sudenga SL, Junkins A, Al Diffalha S, Saag MS, Shrestha S. A 12-year retrospective evaluation of anal pre-cancerous lesions and cancer in people living with HIV-1 infection in the Southeastern U.S. Infect Agent Cancer. 2021 Feb 2/17/2021; 16(1): 14. PMID: 33596943, PMCID: PMC7891006, PII: 10.1186/s13027-021-00354-7, DOI: 10.1186/s13027-021-00354-7, ISSN: 1750-9378.

Jongen VW, Schim van der Loeff MF, Botha MH, Sudenga SL, Abrahamsen ME, Giuliano AR. Incidence and risk factors of C. trachomatis and N. gonorrhoeae among young women from the Western Cape, South Africa: The EVRI study. PLoS One. 2021; 16(5): e0250871. PMID: 33939747, PMCID: PMC8092667, PII: PONE-D-20-31236, DOI: 10.1371/journal.pone.0250871, ISSN: 1932-6203.

Le VQ, Nguyen VH, Nguyen VH, Nguyen TL, Sudenga SL, Trinh LH, Nguyen VT, Nguyen TTH. Epidemiological Characteristics of Advanced Hepatocellular Carcinoma in the Northern Region of Vietnam. Cancer Control. 2019 Jan; 26(1): 1073274819862793. PMID: 31290350, PMCID: PMC6620729, DOI: 10.1177/1073274819862793, ISSN: 1526-2359.

Mainali B, Schabath MB, Sudenga SL, Ye C, Wiener HW, Villa LL, Giuliano AR, Shrestha S. Variants in Immune-related Genes and Genital HPV 16 Persistence in Men. Papillomavirus Res [print-electronic]. 2018 Aug 8/6/2018; PMID: 30092369, PII: S2405-8521(18)30039-9, DOI: 10.1016/j.pvr.2018.08.001, ISSN: 2405-8521.

Pamnani SJ, Sudenga SL, Rollison DE, Ingles DJ, Abrahamsen M, Villa LL, Lazcano-Ponce E, Huang Y, Borenstein A, Giuliano AR. Recurrence of Genital Infections with Nine HPV Vaccine Types (6, 11, 16, 18, 31, 33, 45, 52, and 58) among Men in the HPV Infection in Men (HIM) Study. J. Infect. Dis [print-electronic]. 2018 May 5/24/2018; PMID: 29800222, PII: 5002064, DOI: 10.1093/infdis/jiy300, ISSN: 1537-6613.

Nunes EM, López RVM, Sudenga SL, Gheit T, Tommasino M, Baggio ML, Ferreira S, Galan L, Silva RC, Lazcano-Ponce E, Giuliano AR, Villa LL, Sichero L, . Concordance of Beta-papillomavirus across anogenital and oral anatomic sites of men: The HIM Study. Virology [print-electronic]. 2017 Oct; 510: 55-9. PMID: 28708973, PII: S0042-6822(17)30217-9, DOI: 10.1016/j.virol.2017.07.006, ISSN: 1096-0341.

Sudenga SL, Torres BN, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim Van der Loeff MF, Van der Laan LE, Kipping S, Taylor D, Giuliano AR. HPV SEROSTATUS PRE- AND POST-VACCINATION IN A RANDOMIZED PHASE II PREPAREDNESS TRIAL AMONG YOUNG WESTERN CAPE, SOUTH AFRICAN WOMEN: THE EVRI TRIAL. Papillomavirus Res [print-electronic]. 2017 Jun; 3: 50-6. PMID: 28480334, PMCID: PMC5417542, DOI: 10.1016/j.pvr.2017.02.001.

Menezes LJ, Pokharel U, Sudenga SL, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim van der Loeff MF, van der Laan LE, Kipping S, Taylor D, Giuliano AR. Patterns of prevalent HPV and STI co-infections and associated factors among HIV-negative young Western Cape, South African women: the EVRI trial. Sex Transm Infect [print-electronic]. 2017 May 5/10/2017; PMID: 28490581, PII: sextrans-2016-053046, DOI: 10.1136/sextrans-2016-053046, ISSN: 1472-3263.

Sudenga SL, Torres BN, Silva R, Villa LL, Lazcano-Ponce E, Abrahamsen M, Baggio ML, Salmeron J, Quiterio M, Giuliano AR. Comparison of the natural history of genital HPV infection among men by country: Brazil, Mexico, and the United States. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2017 Apr 4/26/2017; PMID: 28446543, PII: 1055-9965.EPI-17-0040, DOI: 10.1158/1055-9965.EPI-17-0040, ISSN: 1538-7755.

da Silva RJC, Sudenga SL, Sichero L, Baggio ML, Galan L, Cintra R, Torres BN, Stoler M, Giuliano AR, Villa LL. HPV-related external genital lesions among men residing in Brazil. Braz J Infect Dis [print-electronic]. 2017 Apr 4/8/2017; PMID: 28399426, PII: S1413-8670(16)30245-8, DOI: 10.1016/j.bjid.2017.03.004, ISSN: 1678-4391.

Sudenga SL, Nyitray AG, Torres BN, Silva R, Villa L, Lazcano-Ponce E, Abrahamsen M, Baggio ML, Salmeron J, Quiterio M, Giuliano AR. Comparison of anal HPV natural history among men by country of residence: Brazil, Mexico, and the United States. J. Infect [print-electronic]. 2017 Mar 3/28/2017; PMID: 28363585, PII: S0163-4453(17)30087-7, DOI: 10.1016/j.jinf.2017.03.010, ISSN: 1532-2742.

Rahman S, Pierce Campbell CM, Waterboer T, Rollison DE, Ingles DJ, Torres BN, Michel A, Sudenga SL, Pawlita M, Villa LL, Lazcano Ponce E, Borenstein AR, Wang W, Giuliano AR. Seroprevalence of cutaneous human papillomaviruses (HPVs) among men in the multinational HPV Infection in Men study. J. Gen. Virol [print-electronic]. 2016 Dec; 97(12): 3291-301. PMID: 27902363, DOI: 10.1099/jgv.0.000620, ISSN: 1465-2099.

Pamnani SJ, Sudenga SL, Viscidi R, Rollison DE, Torres BN, Ingles DJ, Abrahamsen M, Villa LL, Lazcano-Ponce E, Salmeron J, Quiterio M, Huang Y, Borenstein A, Giuliano AR. Impact of Serum Antibodies to HPV Serotypes 6, 11, 16, and 18 to Risks of Subsequent Genital HPV Infections in Men: The HIM Study. Cancer Res [print-electronic]. 2016 Oct 10/15/2016; 76(20): 6066-75. PMID: 27535333, PII: 0008-5472.CAN-16-0224, DOI: 10.1158/0008-5472.CAN-16-0224, ISSN: 1538-7445.

Sudenga SL, Nelson Torres B, Fulp WJ, Silva R, Villa LL, Lazcano-Ponce E, Ingles DJ, Stoler M, Messina JL, Abrahamsen M, Baggio ML, Salmeron J, Quiterio M, Giuliano AR. Country-Specific HPV-related Genital Disease Among Men Residing in Brazil, Mexico, and the United States: The HIM Study. Int. J. Cancer [print-electronic]. 2016 Sep 9/28/2016; PMID: 27681815, DOI: 10.1002/ijc.30452, ISSN: 1097-0215.

Nunes EM, Sudenga SL, Gheit T, Tommasino M, Baggio ML, Ferreira S, Galan L, Silva RC, Pierce Campbell CM, Lazcano-Ponce E, Giuliano AR, Villa LL, Sichero L, . Diversity of beta-papillomavirus at anogenital and oral anatomic sites of men: The HIM Study. Virology [print-electronic]. 2016 Aug; 495: 33-41. PMID: 27161202, PMCID: PMC4949595, PII: S0042-6822(16)30098-8, DOI: 10.1016/j.virol.2016.04.031, ISSN: 1096-0341.

Sudenga SL, Torres BN, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim Van der Loeff MF, Van der Laan LE, Kipping S, Taylor D, Giuliano AR. Cervical HPV natural history among young Western Cape, South African women: The randomized control EVRI Trial. J. Infect [print-electronic]. 2016 Jan; 72(1): 60-9. PMID: 26476151, PMCID: PMC4698060, PII: S0163-4453(15)00316-3, DOI: 10.1016/j.jinf.2015.10.001, ISSN: 1532-2742.

Sudenga SL, Ingles DJ, Pierce Campbell CM, Lin HY, Fulp WJ, Messina JL, Stoler MH, Abrahamsen M, Villa LL, Lazcano-Ponce E, Giuliano AR. Genital Human Papillomavirus Infection Progression to External Genital Lesions: The HIM Study. Eur. Urol [print-electronic]. 2016 Jan; 69(1): 166-73. PMID: 26051441, PMCID: PMC4670812, PII: S0302-2838(15)00434-0, DOI: 10.1016/j.eururo.2015.05.032, ISSN: 1873-7560.

Ingles DJ, Lin HY, Fulp WJ, Sudenga SL, Lu B, Schabath MB, Papenfuss MR, Abrahamsen ME, Salmeron J, Villa LL, Ponce EL, Giuliano AR. An analysis of HPV infection incidence and clearance by genotype and age in men: The HPV Infection in Men (HIM) Study. Papillomavirus Res [print-electronic]. 2015 Dec; 1: 126-35. PMID: 27547836, PMCID: PMC4986989, DOI: 10.1016/j.pvr.2015.09.001.

Giuliano AR, Viscidi R, Torres BN, Ingles DJ, Sudenga SL, Villa LL, Baggio ML, Abrahamsen M, Quiterio M, Salmeron J, Lazcano-Ponce E. Seroconversion Following Anal and Genital HPV Infection in Men: The HIM Study. Papillomavirus Res. 2015 Dec 12/1/2015; 1: 109-15. PMID: 26688833, PMCID: PMC4680989, DOI: 10.1016/j.pvr.2015.06.007.

Giuliano AR, Nyitray AG, Kreimer AR, Pierce Campbell CM, Goodman MT, Sudenga SL, Monsonego J, Franceschi S. EUROGIN 2014 roadmap: differences in human papillomavirus infection natural history, transmission and human papillomavirus-related cancer incidence by gender and anatomic site of infection. Int. J. Cancer [print-electronic]. 2015 Jun 6/15/2015; 136(12): 2752-60. PMID: 25043222, PMCID: PMC4297584, DOI: 10.1002/ijc.29082, ISSN: 1097-0215.

Giuliano AR, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, van der Laan LE, Papenfuss M, Engelbrecht S, Schim van der Loeff MF, Sudenga SL, Torres BN, Kipping S, Taylor D. High HIV, HPV, and STI prevalence among young Western Cape, South African women: EVRI HIV prevention preparedness trial. J. Acquir. Immune Defic. Syndr. 2015 Feb 2/1/2015; 68(2): 227-35. PMID: 25415290, PMCID: PMC4378717, DOI: 10.1097/QAI.0000000000000425, ISSN: 1944-7884.

Sudenga SL, Shrestha S, Macaluso M, Partridge EE, Johanning GL, Piyathilake CJ. Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infection. Gynecol. Oncol [print-electronic]. 2014 Dec; 135(3): 560-4. PMID: 25281494, PMCID: PMC4268049, PII: S0090-8258(14)01342-0, DOI: 10.1016/j.ygyno.2014.09.015, ISSN: 1095-6859.

Stanley MA, Sudenga SL, Giuliano AR. Alternative dosage schedules with HPV virus-like particle vaccines. Expert Rev Vaccines [print-electronic]. 2014 Aug; 13(8): 1027-38. PMID: 25001893, PMCID: PMC4147727, DOI: 10.1586/14760584.2014.935767, ISSN: 1744-8395.

Sudenga SL, Wiener HW, King CC, Rompalo AM, Cu-Uvin S, Klein RS, Shah KV, Sobel JD, Jamieson DJ, Shrestha S. Dense genotyping of immune-related loci identifies variants associated with clearance of HPV among HIV-positive women in the HIV epidemiology research study (HERS). PLoS ONE. 2014; 9(6): e99109. PMID: 24918582, PMCID: PMC4053382, PII: PONE-D-14-05335, DOI: 10.1371/journal.pone.0099109, ISSN: 1932-6203.

Sudenga SL, Wiener HW, Shendre A, Wilson CM, Tang J, Shrestha S. Variants in interleukin family of cytokines genes influence clearance of high risk HPV in HIV-1 coinfected African-American adolescents. Hum. Immunol [print-electronic]. 2013 Dec; 74(12): 1696-700. PMID: 23973891, PMCID: PMC3842375, PII: S0198-8859(13)00235-8, DOI: 10.1016/j.humimm.2013.08.010, ISSN: 1879-1166.

Sudenga SL, Rositch AF, Otieno WA, Smith JS. Knowledge, attitudes, practices, and perceived risk of cervical cancer among Kenyan women: brief report. Int. J. Gynecol. Cancer. 2013 Jun; 23(5): 895-9. PMID: 23694983, PMCID: PMC3662490, PII: 00009577-201306000-00020, DOI: 10.1097/IGC.0b013e31828e425c, ISSN: 1525-1438.

Sudenga SL, Shrestha S. Key considerations and current perspectives of epidemiological studies on human papillomavirus persistence, the intermediate phenotype to cervical cancer. Int. J. Infect. Dis [print-electronic]. 2013 Apr; 17(4): e216-20. PMID: 23453716, PMCID: PMC3602330, PII: S1201-9712(13)00047-7, DOI: 10.1016/j.ijid.2012.12.027, ISSN: 1878-3511.

Sudenga SL, Kempf MC, McGwin G, Wilson CM, Hook EW, Shrestha S. Incidence, prevalence, and epidemiology of herpes simplex virus-2 in HIV-1-positive and HIV-1-negative adolescents. Sex Transm Dis. 2012 Apr; 39(4): 300-5. PMID: 22421698, PMCID: PMC3306602, PII: 00007435-201204000-00011, DOI: 10.1097/OLQ.0b013e318244a90f, ISSN: 1537-4521.

Kravchenko J, Akushevich I, Sudenga SL, Wilson CM, Levitan EB, Shrestha S. Transitional probability-based model for HPV clearance in HIV-1-positive adolescent females. PLoS ONE [print-electronic]. 2012; 7(1): e30736. PMID: 22292027, PMCID: PMC3265500, PII: PONE-D-11-13246, DOI: 10.1371/journal.pone.0030736, ISSN: 1932-6203.

Sudenga SL, Royse KE, Shrestha S. Role and uptake of human papillomavirus vaccine in adolescent health in the United States. Adolesc Health Med Ther. 2011 Aug; 2011(2): 63-74. PMID: 24155627, PMCID: PMC3804132, DOI: 10.2147/AHMT.S15941.

Shrestha S, Sudenga SL, Smith JS, Bachmann LH, Wilson CM, Kempf MC. The impact of highly active antiretroviral therapy on prevalence and incidence of cervical human papillomavirus infections in HIV-positive adolescents. BMC Infect. Dis. 2010 Oct 10/14/2010; 10: 295. PMID: 20946655, PMCID: PMC2965148, PII: 1471-2334-10-295, DOI: 10.1186/1471-2334-10-295, ISSN: 1471-2334.