Rainelli B. Koumangoye, Ph.D.

Research Instructor

Faculty Appointments
Research Instructor in Anesthesiology
Ph.D., Meharry Medical College, Nashville, TennesseeB.S., University of Quebec, Montreal, CanadaM.S., Laval University Faculty of Medicine, Quebec, Canada
Koumangoye R, Omer S, Delpire E. Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells. Am. J. Physiol., Cell Physiol [print-electronic]. 2018 May 5/2/2018; PMID: 29719172, DOI: 10.1152/ajpcell.00130.2018, ISSN: 1522-1563.

Koumangoye R, Delpire E. DNPEP is not the only peptidase that produces SPAK fragments in kidney. Physiol Rep. 2017 Nov; 5(21): PMID: 29122955, PMCID: PMC5688775, PII: 5/21/e13479, DOI: 10.14814/phy2.13479, ISSN: 2051-817X.

Delpire E, Wolfe L, Flores B, Koumangoye R, Schornak CC, Omer S, Pusey B, Lau C, Markello T, Adams DR. A patient with multisystem dysfunction carries a truncation mutation in human SLC12A2, the gene encoding the Na-K-2Cl cotransporter, NKCC1. Cold Spring Harb Mol Case Stud. 2016 Nov; 2(6): a001289. PMID: 27900370, PMCID: PMC5111002, PII: DelpireMCS001289, DOI: 10.1101/mcs.a001289, ISSN: 2373-2873.

Koumangoye R, Delpire E. The Ste20 kinases SPAK and OSR1 travel between cells through exosomes. Am. J. Physiol., Cell Physiol [print-electronic]. 2016 Jul 7/1/2016; 311(1): C43-53. PMID: 27122160, PMCID: PMC4967142, PII: ajpcell.00080.2016, DOI: 10.1152/ajpcell.00080.2016, ISSN: 1522-1563.

Taylor C, Loomans HA, Le Bras GF, Koumangoye RB, Romero-Morales AI, Quast LL, Zaika AI, El-Rifai W, Andl T, Andl CD. Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma. Oncotarget. 2015 Oct 10/27/2015; 6(33): 34228-44. PMID: 26447543, PMCID: PMC4741448, PII: 5349, DOI: 10.18632/oncotarget.5349, ISSN: 1949-2553.

Koumangoye RB, Andl T, Taubenslag KJ, Zilberman ST, Taylor CJ, Loomans HA, Andl CD. SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells. Mol. Cancer. 2015 Feb 2/3/2015; 14: 24. PMID: 25644061, PMCID: PMC4374188, PII: s12943-014-0284-y, DOI: 10.1186/s12943-014-0284-y, ISSN: 1476-4598.

Le Bras GF, Taylor C, Koumangoye RB, Revetta F, Loomans HA, Andl CD. TGFß loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion. Exp. Cell Res [print-electronic]. 2015 Jan 1/1/2015; 330(1): 29-42. PMID: 25064463, PMCID: PMC4267897, PII: S0014-4827(14)00301-2, DOI: 10.1016/j.yexcr.2014.07.021, ISSN: 1090-2422.

Thompson PD, Sakwe A, Koumangoye R, Yarbrough WG, Ochieng J, Marshall DR. Alpha-2 Heremans Schmid Glycoprotein (AHSG) modulates signaling pathways in head and neck squamous cell carcinoma cell line SQ20B. Exp. Cell Res [print-electronic]. 2014 Feb 2/15/2014; 321(2): 123-32. PMID: 24332981, PMCID: PMC4096485, PII: S0014-4827(13)00520-X, DOI: 10.1016/j.yexcr.2013.12.003, ISSN: 1090-2422.

Koumangoye RB, Nangami GN, Thompson PD, Agboto VK, Ochieng J, Sakwe AM. Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors. Mol. Cancer. 2013 Dec 12/19/2013; 12(1): 167. PMID: 24354805, PMCID: PMC3922904, PII: 1476-4598-12-167, DOI: 10.1186/1476-4598-12-167, ISSN: 1476-4598.

Watson K, Koumangoye R, Thompson P, Sakwe AM, Patel T, Pratap S, Ochieng J. Fetuin-A triggers the secretion of a novel set of exosomes in detached tumor cells that mediate their adhesion and spreading. FEBS Lett [print-electronic]. 2012 Sep 9/21/2012; 586(19): 3458-63. PMID: 22980907, PMCID: PMC3455109, PII: S0014-5793(12)00650-3, DOI: 10.1016/j.febslet.2012.07.071, ISSN: 1873-3468.

Sakwe AM, Koumangoye R, Guillory B, Ochieng J. Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions. Exp. Cell Res [print-electronic]. 2011 Apr 4/1/2011; 317(6): 823-37. PMID: 21185831, PMCID: PMC3049817, PII: S0014-4827(10)00566-5, DOI: 10.1016/j.yexcr.2010.12.008, ISSN: 1090-2422.

Koumangoye RB, Sakwe AM, Goodwin JS, Patel T, Ochieng J. Detachment of breast tumor cells induces rapid secretion of exosomes which subsequently mediate cellular adhesion and spreading. PLoS ONE [print-electronic]. 2011; 6(9): e24234. PMID: 21915303, PMCID: PMC3167827, PII: PONE-D-11-07366, DOI: 10.1371/journal.pone.0024234, ISSN: 1932-6203.

Sakwe AM, Koumangoye R, Goodwin SJ, Ochieng J. Fetuin-A ({alpha}2HS-glycoprotein) is a major serum adhesive protein that mediates growth signaling in breast tumor cells. J. Biol. Chem [print-electronic]. 2010 Dec 12/31/2010; 285(53): 41827-35. PMID: 20956534, PMCID: PMC3009910, PII: M110.128926, DOI: 10.1074/jbc.M110.128926, ISSN: 1083-351X.

Guillory B, Sakwe AM, Saria M, Thompson P, Adhiambo C, Koumangoye R, Ballard B, Binhazim A, Cone C, Jahanen-Dechent W, Ochieng J. Lack of fetuin-A (alpha2-HS-glycoprotein) reduces mammary tumor incidence and prolongs tumor latency via the transforming growth factor-beta signaling pathway in a mouse model of breast cancer. Am. J. Pathol [print-electronic]. 2010 Nov; 177(5): 2635-44. PMID: 20847285, PMCID: PMC2966818, PII: S0002-9440(10)60312-4, DOI: 10.2353/ajpath.2010.100177, ISSN: 1525-2191.