Faculty Appointments
Associate Professor of Psychology
Associate Professor of Biomedical EngineeringAssociate Professor of Biomedical Engineering
Education
Ph.D., Neuroscience, University of Arizona, Tucson, ArizonaB.A., Cognitive Science, Psychology and BIology, Rice University, Houston, Texas
Research Keywords
Neuroscience, Neuropharmacology, Cognitive neurophysiology, Computational neuroethology
Publications
Abbaspoor S, Hussin AT, Hoffman KL. Theta- and gamma-band oscillatory uncoupling in the macaque hippocampus. Elife. 2023 May 5/4/2023; 12: PMID: 37139864, PMCID: PMC10208636, PII: 86548, DOI: 10.7554/eLife.86548, ISSN: 2050-084X.
Hussin AT, Abbaspoor S, Hoffman KL. Retrosplenial and Hippocampal Synchrony during Retrieval of Old Memories in Macaques. J Neurosci [print-electronic]. 2022 Oct 10/19/2022; 42(42): 7947-56. PMID: 36261267, PMCID: PMC9617609, PII: JNEUROSCI.0001-22.2022, DOI: 10.1523/JNEUROSCI.0001-22.2022, ISSN: 1529-2401.
Liu AA, Henin S, Abbaspoor S, Bragin A, Buffalo EA, Farrell JS, Foster DJ, Frank LM, Gedankien T, Gotman J, Guidera JA, Hoffman KL, Jacobs J, Kahana MJ, Li L, Liao Z, Lin JJ, Losonczy A, Malach R, van der Meer MA, McClain K, McNaughton BL, Norman Y, Navas-Olive A, de la Prida LM, Rueckemann JW, Sakon JJ, Skelin I, Soltesz I, Staresina BP, Weiss SA, Wilson MA, Zaghloul KA, Zugaro M, Buzsáki G. A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations. Nat Commun. 2022 Oct 10/12/2022; 13(1): 6000. PMID: 36224194, PMCID: PMC9556539, PII: 10.1038/s41467-022-33536-x, DOI: 10.1038/s41467-022-33536-x, ISSN: 2041-1723.
Katz CN, Schjetnan AGP, Patel K, Barkley V, Hoffman KL, Kalia SK, Duncan KD, Valiante TA. A corollary discharge mediates saccade-related inhibition of single units in mnemonic structures of the human brain. Curr Biol [print-electronic]. 2022 Jul 7/25/2022; 32(14): 3082-3094.e4-3094.e4. PMID: 35779529, PII: S0960-9822(22)00927-7, DOI: 10.1016/j.cub.2022.06.015, ISSN: 1879-0445.
Womelsdorf T, Thomas C, Neumann A, Watson MR, Banaie Boroujeni K, Hassani SA, Parker J, Hoffman KL. A Kiosk Station for the Assessment of Multiple Cognitive Domains and Cognitive Enrichment of Monkeys. Front Behav Neurosci. 2021; 15: 721069. PMID: 34512289, PMCID: PMC8426617, DOI: 10.3389/fnbeh.2021.721069, ISSN: 1662-5153.
Katz CN, Patel K, Talakoub O, Groppe D, Hoffman K, Valiante TA. Differential Generation of Saccade, Fixation, and Image-Onset Event-Related Potentials in the Human Mesial Temporal Lobe. Cereb Cortex. 2020 Sep 9/3/2020; 30(10): 5502-16. PMID: 32494805, PMCID: PMC7472212, PII: 5850969, DOI: 10.1093/cercor/bhaa132, ISSN: 1460-2199.
Hussin AT, Leonard TK, Hoffman KL. Sharp-wave ripple features in macaques depend on behavioral state and cell-type specific firing. Hippocampus [print-electronic]. 2020 Jan; 30(1): 50-9. PMID: 30371963, PMCID: PMC7004038, DOI: 10.1002/hipo.23046, ISSN: 1098-1063.
Sayegh PF, Gorbet DJ, Hawkins KM, Hoffman KL, Sergio LE. The Contribution of Different Cortical Regions to the Control of Spatially Decoupled Eye-Hand Coordination. J Cogn Neurosci [print-electronic]. 2017 Jul; 29(7): 1194-211. PMID: 28253075, DOI: 10.1162/jocn_a_01111, ISSN: 1530-8898.
Montefusco-Siegmund R, Leonard TK, Hoffman KL. Hippocampal gamma-band Synchrony and pupillary responses index memory during visual search. Hippocampus [print-electronic]. 2017 Apr; 27(4): 425-34. PMID: 28032676, DOI: 10.1002/hipo.22702, ISSN: 1098-1063.
Dragan MC, Leonard TK, Lozano AM, McAndrews MP, Ng K, Ryan JD, Tang-Wai DF, Wynn JS, Hoffman KL. Pupillary responses and memory-guided visual search reveal age-related and Alzheimer's-related memory decline. Behav Brain Res [print-electronic]. 2017 Mar 3/30/2017; 322(Pt B): 351-61. PMID: 27616343, PII: S0166-4328(16)30597-6, DOI: 10.1016/j.bbr.2016.09.014, ISSN: 1872-7549.
Leonard TK, Hoffman KL. Sharp-Wave Ripples in Primates Are Enhanced near Remembered Visual Objects. Curr Biol [print-electronic]. 2017 Jan 1/23/2017; 27(2): 257-62. PMID: 28041797, PII: S0960-9822(16)31353-7, DOI: 10.1016/j.cub.2016.11.027, ISSN: 1879-0445.
Wynn JS, Bone MB, Dragan MC, Hoffman KL, Buchsbaum BR, Ryan JD. Selective scanpath repetition during memory-guided visual search. Vis cogn [print-electronic]. 2016 Jan 1/2/2016; 24(1): 15-37. PMID: 27570471, PMCID: PMC4975086, PII: 1175531, DOI: 10.1080/13506285.2016.1175531, ISSN: 1350-6285.
Talakoub O, Gomez Palacio Schjetnan A, Valiante TA, Popovic MR, Hoffman KL. Closed-Loop Interruption of Hippocampal Ripples through Fornix Stimulation in the Non-Human Primate. Brain Stimul [print-electronic]. 2016; 9(6): 911-8. PMID: 27576185, PII: S1935-861X(16)30202-9, DOI: 10.1016/j.brs.2016.07.010, ISSN: 1876-4754.
Leonard TK, Mikkila JM, Eskandar EN, Gerrard JL, Kaping D, Patel SR, Womelsdorf T, Hoffman KL. Sharp Wave Ripples during Visual Exploration in the Primate Hippocampus. J Neurosci. 2015 Nov 11/4/2015; 35(44): 14771-82. PMID: 26538648, PMCID: PMC4635128, PII: 35/44/14771, DOI: 10.1523/JNEUROSCI.0864-15.2015, ISSN: 1529-2401.
Sayegh PF, Hawkins KM, Neagu B, Crawford JD, Hoffman KL, Sergio LE. Decoupling the actions of the eyes from the hand alters beta and gamma synchrony within SPL. J Neurophysiol [print-electronic]. 2014 Jun 6/1/2014; 111(11): 2210-21. PMID: 24598517, PII: jn.00793.2013, DOI: 10.1152/jn.00793.2013, ISSN: 1522-1598.
Sayegh PF, Hawkins KM, Hoffman KL, Sergio LE. Differences in spectral profiles between rostral and caudal premotor cortex when hand-eye actions are decoupled. J Neurophysiol [print-electronic]. 2013 Aug; 110(4): 952-63. PMID: 23699054, PII: jn.00764.2012, DOI: 10.1152/jn.00764.2012, ISSN: 1522-1598.
Hoffman KL, Dragan MC, Leonard TK, Micheli C, Montefusco-Siegmund R, Valiante TA. Saccades during visual exploration align hippocampal 3-8 Hz rhythms in human and non-human primates. Front Syst Neurosci. 2013; 7: 43. PMID: 24009562, PMCID: PMC3757337, DOI: 10.3389/fnsys.2013.00043, ISSN: 1662-5137.
Leonard TK, Blumenthal G, Gothard KM, Hoffman KL. How macaques view familiarity and gaze in conspecific faces. Behav Neurosci [print-electronic]. 2012 Dec; 126(6): 781-91. PMID: 23067381, PII: 2012-27906-001, DOI: 10.1037/a0030348, ISSN: 1939-0084.
Bartlett AM, Ovaysikia S, Logothetis NK, Hoffman KL. Saccades during object viewing modulate oscillatory phase in the superior temporal sulcus. J Neurosci. 2011 Dec 12/14/2011; 31(50): 18423-32. PMID: 22171044, PMCID: PMC6623894, PII: 31/50/18423, DOI: 10.1523/JNEUROSCI.4102-11.2011, ISSN: 1529-2401.
Chau VL, Murphy EF, Rosenbaum RS, Ryan JD, Hoffman KL. A Flicker Change Detection Task Reveals Object-in-Scene Memory Across Species. Front Behav Neurosci. 2011; 5: 58. PMID: 21960963, PMCID: PMC3176411, DOI: 10.3389/fnbeh.2011.00058, ISSN: 1662-5153.
Hoffman KL, Logothetis NK. Cortical mechanisms of sensory learning and object recognition. Philos Trans R Soc Lond B Biol Sci. 2009 Feb 2/12/2009; 364(1515): 321-9. PMID: 18977728, PMCID: PMC2674481, PII: C1845666N1128233, DOI: 10.1098/rstb.2008.0271, ISSN: 1471-2970.
Hoffman KL, Battaglia FP, Harris K, MacLean JN, Marshall L, Mehta MR. The upshot of up states in the neocortex: from slow oscillations to memory formation. J Neurosci. 2007 Oct 10/31/2007; 27(44): 11838-41. PMID: 17978020, PMCID: PMC6673366, PII: 27/44/11838, DOI: 10.1523/JNEUROSCI.3501-07.2007, ISSN: 1529-2401.
Hussin AT, Abbaspoor S, Hoffman KL. Retrosplenial and Hippocampal Synchrony during Retrieval of Old Memories in Macaques. J Neurosci [print-electronic]. 2022 Oct 10/19/2022; 42(42): 7947-56. PMID: 36261267, PMCID: PMC9617609, PII: JNEUROSCI.0001-22.2022, DOI: 10.1523/JNEUROSCI.0001-22.2022, ISSN: 1529-2401.
Liu AA, Henin S, Abbaspoor S, Bragin A, Buffalo EA, Farrell JS, Foster DJ, Frank LM, Gedankien T, Gotman J, Guidera JA, Hoffman KL, Jacobs J, Kahana MJ, Li L, Liao Z, Lin JJ, Losonczy A, Malach R, van der Meer MA, McClain K, McNaughton BL, Norman Y, Navas-Olive A, de la Prida LM, Rueckemann JW, Sakon JJ, Skelin I, Soltesz I, Staresina BP, Weiss SA, Wilson MA, Zaghloul KA, Zugaro M, Buzsáki G. A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations. Nat Commun. 2022 Oct 10/12/2022; 13(1): 6000. PMID: 36224194, PMCID: PMC9556539, PII: 10.1038/s41467-022-33536-x, DOI: 10.1038/s41467-022-33536-x, ISSN: 2041-1723.
Katz CN, Schjetnan AGP, Patel K, Barkley V, Hoffman KL, Kalia SK, Duncan KD, Valiante TA. A corollary discharge mediates saccade-related inhibition of single units in mnemonic structures of the human brain. Curr Biol [print-electronic]. 2022 Jul 7/25/2022; 32(14): 3082-3094.e4-3094.e4. PMID: 35779529, PII: S0960-9822(22)00927-7, DOI: 10.1016/j.cub.2022.06.015, ISSN: 1879-0445.
Womelsdorf T, Thomas C, Neumann A, Watson MR, Banaie Boroujeni K, Hassani SA, Parker J, Hoffman KL. A Kiosk Station for the Assessment of Multiple Cognitive Domains and Cognitive Enrichment of Monkeys. Front Behav Neurosci. 2021; 15: 721069. PMID: 34512289, PMCID: PMC8426617, DOI: 10.3389/fnbeh.2021.721069, ISSN: 1662-5153.
Katz CN, Patel K, Talakoub O, Groppe D, Hoffman K, Valiante TA. Differential Generation of Saccade, Fixation, and Image-Onset Event-Related Potentials in the Human Mesial Temporal Lobe. Cereb Cortex. 2020 Sep 9/3/2020; 30(10): 5502-16. PMID: 32494805, PMCID: PMC7472212, PII: 5850969, DOI: 10.1093/cercor/bhaa132, ISSN: 1460-2199.
Hussin AT, Leonard TK, Hoffman KL. Sharp-wave ripple features in macaques depend on behavioral state and cell-type specific firing. Hippocampus [print-electronic]. 2020 Jan; 30(1): 50-9. PMID: 30371963, PMCID: PMC7004038, DOI: 10.1002/hipo.23046, ISSN: 1098-1063.
Sayegh PF, Gorbet DJ, Hawkins KM, Hoffman KL, Sergio LE. The Contribution of Different Cortical Regions to the Control of Spatially Decoupled Eye-Hand Coordination. J Cogn Neurosci [print-electronic]. 2017 Jul; 29(7): 1194-211. PMID: 28253075, DOI: 10.1162/jocn_a_01111, ISSN: 1530-8898.
Montefusco-Siegmund R, Leonard TK, Hoffman KL. Hippocampal gamma-band Synchrony and pupillary responses index memory during visual search. Hippocampus [print-electronic]. 2017 Apr; 27(4): 425-34. PMID: 28032676, DOI: 10.1002/hipo.22702, ISSN: 1098-1063.
Dragan MC, Leonard TK, Lozano AM, McAndrews MP, Ng K, Ryan JD, Tang-Wai DF, Wynn JS, Hoffman KL. Pupillary responses and memory-guided visual search reveal age-related and Alzheimer's-related memory decline. Behav Brain Res [print-electronic]. 2017 Mar 3/30/2017; 322(Pt B): 351-61. PMID: 27616343, PII: S0166-4328(16)30597-6, DOI: 10.1016/j.bbr.2016.09.014, ISSN: 1872-7549.
Leonard TK, Hoffman KL. Sharp-Wave Ripples in Primates Are Enhanced near Remembered Visual Objects. Curr Biol [print-electronic]. 2017 Jan 1/23/2017; 27(2): 257-62. PMID: 28041797, PII: S0960-9822(16)31353-7, DOI: 10.1016/j.cub.2016.11.027, ISSN: 1879-0445.
Wynn JS, Bone MB, Dragan MC, Hoffman KL, Buchsbaum BR, Ryan JD. Selective scanpath repetition during memory-guided visual search. Vis cogn [print-electronic]. 2016 Jan 1/2/2016; 24(1): 15-37. PMID: 27570471, PMCID: PMC4975086, PII: 1175531, DOI: 10.1080/13506285.2016.1175531, ISSN: 1350-6285.
Talakoub O, Gomez Palacio Schjetnan A, Valiante TA, Popovic MR, Hoffman KL. Closed-Loop Interruption of Hippocampal Ripples through Fornix Stimulation in the Non-Human Primate. Brain Stimul [print-electronic]. 2016; 9(6): 911-8. PMID: 27576185, PII: S1935-861X(16)30202-9, DOI: 10.1016/j.brs.2016.07.010, ISSN: 1876-4754.
Leonard TK, Mikkila JM, Eskandar EN, Gerrard JL, Kaping D, Patel SR, Womelsdorf T, Hoffman KL. Sharp Wave Ripples during Visual Exploration in the Primate Hippocampus. J Neurosci. 2015 Nov 11/4/2015; 35(44): 14771-82. PMID: 26538648, PMCID: PMC4635128, PII: 35/44/14771, DOI: 10.1523/JNEUROSCI.0864-15.2015, ISSN: 1529-2401.
Sayegh PF, Hawkins KM, Neagu B, Crawford JD, Hoffman KL, Sergio LE. Decoupling the actions of the eyes from the hand alters beta and gamma synchrony within SPL. J Neurophysiol [print-electronic]. 2014 Jun 6/1/2014; 111(11): 2210-21. PMID: 24598517, PII: jn.00793.2013, DOI: 10.1152/jn.00793.2013, ISSN: 1522-1598.
Sayegh PF, Hawkins KM, Hoffman KL, Sergio LE. Differences in spectral profiles between rostral and caudal premotor cortex when hand-eye actions are decoupled. J Neurophysiol [print-electronic]. 2013 Aug; 110(4): 952-63. PMID: 23699054, PII: jn.00764.2012, DOI: 10.1152/jn.00764.2012, ISSN: 1522-1598.
Hoffman KL, Dragan MC, Leonard TK, Micheli C, Montefusco-Siegmund R, Valiante TA. Saccades during visual exploration align hippocampal 3-8 Hz rhythms in human and non-human primates. Front Syst Neurosci. 2013; 7: 43. PMID: 24009562, PMCID: PMC3757337, DOI: 10.3389/fnsys.2013.00043, ISSN: 1662-5137.
Leonard TK, Blumenthal G, Gothard KM, Hoffman KL. How macaques view familiarity and gaze in conspecific faces. Behav Neurosci [print-electronic]. 2012 Dec; 126(6): 781-91. PMID: 23067381, PII: 2012-27906-001, DOI: 10.1037/a0030348, ISSN: 1939-0084.
Bartlett AM, Ovaysikia S, Logothetis NK, Hoffman KL. Saccades during object viewing modulate oscillatory phase in the superior temporal sulcus. J Neurosci. 2011 Dec 12/14/2011; 31(50): 18423-32. PMID: 22171044, PMCID: PMC6623894, PII: 31/50/18423, DOI: 10.1523/JNEUROSCI.4102-11.2011, ISSN: 1529-2401.
Chau VL, Murphy EF, Rosenbaum RS, Ryan JD, Hoffman KL. A Flicker Change Detection Task Reveals Object-in-Scene Memory Across Species. Front Behav Neurosci. 2011; 5: 58. PMID: 21960963, PMCID: PMC3176411, DOI: 10.3389/fnbeh.2011.00058, ISSN: 1662-5153.
Hoffman KL, Logothetis NK. Cortical mechanisms of sensory learning and object recognition. Philos Trans R Soc Lond B Biol Sci. 2009 Feb 2/12/2009; 364(1515): 321-9. PMID: 18977728, PMCID: PMC2674481, PII: C1845666N1128233, DOI: 10.1098/rstb.2008.0271, ISSN: 1471-2970.
Hoffman KL, Battaglia FP, Harris K, MacLean JN, Marshall L, Mehta MR. The upshot of up states in the neocortex: from slow oscillations to memory formation. J Neurosci. 2007 Oct 10/31/2007; 27(44): 11838-41. PMID: 17978020, PMCID: PMC6673366, PII: 27/44/11838, DOI: 10.1523/JNEUROSCI.3501-07.2007, ISSN: 1529-2401.