Yike Li, M.D., Ph.D.

Research Assistant Professor

Faculty Appointments
Research Assistant Professor of Otolaryngology
M.D., Fudan University, Shanghai, ChinaPh.D., Vanderbilt University, Nashville, Tennessee
Office Address
1161 21st Avenue South, Medical Center North, Rm. S2211
Nashville, TN 37232
Research Description
Dr. Li is currently a research assistant professor in the Department of Otolaryngology at Vanderbilt University Medical Center. He obtained his M.D. degree from Fudan University in China, and Ph.D. degree in hearing and speech sciences from Vanderbilt University. He completed his residency training in otolaryngology in Shanghai Eye and ENT hospital. Dr. Li has been working in the field of otolaryngology for over 10 years. His research interests include neurolaryngology, voice disorder, hearing loss, and artificial intelligence. Most of his recent publications focus on the application of electrical stimulation to the laryngeal muscles as a treatment approach to vocal fold paralysis. He is currently working on an NIH-funded clinical trial to investigate using an implantable electrical stimulator in the treatment of bilateral vocal fold paralysis in humans. He is also interested in exploring a similar approach in the management of facial paralysis. In addition, he is now engaged in applying machine learning techniques in the detection and diagnosis of head and neck diseases.

Research Keywords
Vocal fold paralysis; Dysphonia; Facial paralysis; Hearing loss; Machine learning; Artificial intelligence
Li Y, Zealear D. Publication delays in peer-reviewed journals of otolaryngology, audiology and speech language pathology. Journal of Postdoctoral Research. 2018 May; 6(5): 1-24.

Li Y, Garrett G, Zealear D. Current Treatment Options for Bilateral Vocal Fold Paralysis: A State-of-the-Art Review. Clin Exp Otorhinolaryngol [print-electronic]. 2017 Sep; 10(3): 203-12. PMID: 28669149, PMCID: PMC5545703, PII: ceo.2017.00199, DOI: 10.21053/ceo.2017.00199, ISSN: 1976-8710.

Li Y. Interventions in management of blood viscosity for idiopathic sudden sensorineural hearing loss: A meta-analysis. J Health Res Rev. 2017 Jun 6/15/2017; 4(2): 50-61.

Li Y, Huang S, Zealear D. An implantable system for In Vivo chronic electromyographic study in the larynx. Muscle Nerve [print-electronic]. 2017 May; 55(5): 706-14. PMID: 27543847, DOI: 10.1002/mus.25384, ISSN: 1097-4598.

Li Y, Yang JM, Huang YB, Ren DD, Chi FL. Shrinkage of ipsilateral taste buds and hyperplasia of contralateral taste buds following chorda tympani nerve transection. Neural Regen Res. 2015 Jun; 10(6): 989-95. PMID: 26199619, PMCID: PMC4498364, PII: NRR-10-989, DOI: 10.4103/1673-5374.158366, ISSN: 1673-5374.

Zealear DL, Mainthia R, Li Y, Kunibe I, Katada A, Billante C, Nomura K. Stimulation of denervated muscle promotes selective reinnervation, prevents synkinesis, and restores function. Laryngoscope [print-electronic]. 2014 May; 124(5): E180-7. PMID: 24254367, DOI: 10.1002/lary.24454, ISSN: 1531-4995.

Li Y, Pearce EC, Mainthia R, Athavale SM, Dang J, Ashmead DH, Garrett CG, Rousseau B, Billante CR, Zealear DL. Comparison of ventilation and voice outcomes between unilateral laryngeal pacing and unilateral cordotomy for the treatment of bilateral vocal fold paralysis. ORL J. Otorhinolaryngol. Relat. Spec [print-electronic]. 2013; 75(2): 68-73. PMID: 23736349, PMCID: PMC3798066, PII: 000345501, DOI: 10.1159/000345501, ISSN: 1423-0275.

Yang JM, Chi FL, Han Z, Huang YB, Li Y. Clinical characteristics of patients with labyrinthine fistulae caused by middle ear cholesteatoma. Chin. Med. J. 2013; 126(11): 2116-9. PMID: 23769568, ISSN: 0366-6999.

Li Y, Chi FL, Wang SY, Wang WQ, Yang JM, Huang YB. Cutaneous neuroendocrine carcinoma of the external auditory canal: a case report and review of the literature. Case Rep Otolaryngol. 2012; 2012: PMID: 22928140, PMCID: PMC3420451, DOI: 10.1155/2012/941065, ISSN: 2090-6773.

Huang Y, Chi F, Han Z, Yang J, Gao W, Li Y. New ectopic vestibular hair cell-like cells induced by Math1 gene transfer in postnatal rats. Brain Res [print-electronic]. 2009 Jun 6/18/2009; 1276: 31-8. PMID: 19397899, PII: S0006-8993(09)00787-2, DOI: 10.1016/j.brainres.2009.04.036, ISSN: 1872-6240.