Erika Danielle Dean, Ph.D.

Research Assistant Professor

danielle.dean@vanderbilt.edu
Faculty Appointments
Research Assistant Professor of Medicine
Education
Ph.D., Molecular and Systems Pharmacology, Emory University, Atlanta, GeorgiaM.S., Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TennesseeB.S., Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee
Publications
Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean E Danielle, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E. Loss of mTORC1 signaling alters pancreatic a cell mass and impairs glucagon secretion. J. Clin. Invest. 2017 Dec 12/1/2017; 127(12): 4379-93. PMID: 29106387, PMCID: PMC5707167, PII: 90004, DOI: 10.1172/JCI90004, ISSN: 1558-8238.

Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC. Interrupted Glucagon Signaling Reveals Hepatic a Cell Axis and Role for L-Glutamine in a Cell Proliferation. Cell Metab. 2017 Jun 6/6/2017; 25(6): 1362-1373.e5. PMID: 28591638, PMCID: PMC5572896, PII: S1550-4131(17)30300-5, DOI: 10.1016/j.cmet.2017.05.011, ISSN: 1932-7420.

Dean ED, Unger RH, Holland WL. Glucagon antagonism in islet cell proliferation. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2017 Mar 3/21/2017; 114(12): 3006-8. PMID: 28283660, PMCID: PMC5373377, PII: 1700468114, DOI: 10.1073/pnas.1700468114, ISSN: 1091-6490.

Li M, Dean ED, Zhao L, Nicholson WE, Powers AC, Chen W. Glucagon receptor inactivation leads to a-cell hyperplasia in zebrafish. J. Endocrinol. 2015 Nov; 227(2): 93-103. PMID: 26446275, PMCID: PMC4598637, PII: 227/2/93, DOI: 10.1530/JOE-15-0284, ISSN: 1479-6805.

Longuet C, Robledo AM, Dean ED, Dai C, Ali S, McGuinness I, de Chavez V, Vuguin PM, Charron MJ, Powers AC, Drucker DJ. Liver-specific disruption of the murine glucagon receptor produces a-cell hyperplasia: evidence for a circulating a-cell growth factor. Diabetes [print-electronic]. 2013 Apr; 62(4): 1196-205. PMID: 23160527, PMCID: PMC3609565, PII: db11-1605, DOI: 10.2337/db11-1605, ISSN: 1939-327X.