Jennifer C. Andrews, M.D.

Associate Professor

jennifer.andrews@vumc.org
Faculty Appointments
Associate Professor of Pathology, Microbiology and Immunology Associate Professor of Pediatrics
Education
M.S.C.R, Emory University, Atlanta, GeorgiaM.D., University of South Florida, Tampa, FloridaB.S., Biological Sciences, Florida State University, Tallahassee, Florida
Research Description
Dr. Andrews is an internationally recognized expert in Pediatric Transfusion Medicine and participates in international and multi-institutional clinical trials investigating safe blood transfusions and practices and laboratory testing, especially in children. She also leads a multidisciplinary team in Patient Blood Management and is board-certified in Clinical Informatics. Her research interests include medical education, Pediatric Transfusion Medicine, blood utilization and use of technology to optimize practice.
Clinical Description
Dr. Andrews completed her residency in Pediatrics at the University of North Carolina-Chapel Hill in 2007, her fellowship in Pediatric Hematology/Oncology at Emory University in 2011, and her fellowship in Transfusion Medicine/Blood Banking at Stanford in 2012. She was a Clinical Assistant and Associate Professor of Pathology and Pediatrics at Stanford from 2012 until she joined the faculty at Vanderbilt in the summer of 2018. Dr. Andrews practices benign Hematology at Monroe Carell Jr. Children's Hospital, which includes the care of children with anemia, neutropenia, thrombocytopenia and other blood disorders. Dr. Andrews also practices Transfusion Medicine, where she cares for adults and children needing apheresis procedures including sickle cell patients. She has won multiple teaching awards from medical students, residents and fellows at Stanford University for her clinical teaching.
Research Keywords
Clinical trials, Pediatric Transfusion Medicine, blood utilization
Clinical Research Keywords
Pediatric Hematology, Pediatric Transfusion Medicine
Publications
Andrews J, Josephson CD, Young P, Spinella PC, Yazer MH. Weighing the risk of hemolytic disease of the newborn versus the benefits of using of RhD-positive blood products in trauma. Transfusion [print-electronic]. 2023 May; 63 Suppl 3: S4-S9-S9. PMID: 37070798, DOI: 10.1111/trf.17352, ISSN: 1537-2995.

Sood SB, Walker LA, Ramanujam R, Hardison D, Andrews J, Smith AH, Bridges BC. The Use of Antifactor Xa Assays in a Comprehensive Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Protocol is Associated with Increased Survival and Significant Blood Product Cost-Savings. J Pediatr Intensive Care. 2022 Dec; 11(4): 341-8. PMID: 36388079, PMCID: PMC9649293, PII: 2000146, DOI: 10.1055/s-0041-1726455, ISSN: 2146-4618.

Stein DM, Upperman JS, Livingston DH, Andrews J, Bulger EM, Cohen MJ, Eastridge BJ, Fontaine MJ, Guillamondegui O, Hess JR, Jenkins DH, Kaups KL, Nance ML, Spinella PC, Zarzaur BL, Zonies D, Coimbra R. National blood shortage: A call to action from the trauma community. J Trauma Acute Care Surg [print-electronic]. 2022 Sep 9/1/2022; 93(3): e119-e122-e122. PMID: 35610747, PII: 01586154-202209000-00021, DOI: 10.1097/TA.0000000000003715, ISSN: 2163-0763.

Ogbenna AA, Akinsete AM, Kalejaiye OO, Matthew OK, Sharma D, Andrews J, Kassim AA. Reduction in seroprevalence of viral transfusion-transmitted infections in southwest Nigeria in children with sickle cell disease using an enhanced screening strategy. Br J Haematol [print-electronic]. 2022 Aug; 198(4): 745-52. PMID: 35719004, DOI: 10.1111/bjh.18313, ISSN: 1365-2141.

Hughes C, Sterling B, Andrews J. Successful Orthotopic Heart Transplantation in a Patient with Anti-U Antibody. Lab Med. 2022 Jul 7/4/2022; 53(4): e77-e78-e78. PMID: 34725705, PII: 6415349, DOI: 10.1093/labmed/lmab100, ISSN: 1943-7730.

McCoy AB, Russo EM, Johnson KB, Addison B, Patel N, Wanderer JP, Mize DE, Jackson JG, Reese TJ, Littlejohn S, Patterson L, French T, Preston D, Rosenbury A, Valdez C, Nelson SD, Aher CV, Alrifai MW, Andrews J, Cobb C, Horst SN, Johnson DP, Knake LA, Lewis AA, Parks L, Parr SK, Patel P, Patterson BL, Smith CM, Suszter KD, Turer RW, Wilcox LJ, Wright AP, Wright A. Clinician collaboration to improve clinical decision support: the Clickbusters initiative. J Am Med Inform Assoc. 2022 May 5/11/2022; 29(6): 1050-9. PMID: 35244165, PMCID: PMC9093034, PII: 6542395, DOI: 10.1093/jamia/ocac027, ISSN: 1527-974X.

Delaney M, Andrews J, Virk M, Barber JR, Bost JE, Baech J, Feys HB. Multinational Analysis of Children Transfused With Pathogen Inactivated Platelets. Hosp Pediatr. 2022 Mar 3/1/2022; 12(3): 311-6. PMID: 35169851, PII: 184789, DOI: 10.1542/hpeds.2021-006284, ISSN: 2154-1671.

Walker SC, Ransom M, Sood S, Andrews J, Smith CM. Respiratory failure and shock in an infant with severe anemia. Clin Case Rep. 2021 Sep; 9(9): e04852. PMID: 34584715, PMCID: PMC8455968, PII: CCR34852, DOI: 10.1002/ccr3.4852, ISSN: 2050-0904.

Lieberman L, Andrews J, Evans MD, Cohn CS. Comparison of prenatal anti-D titration testing by gel and tube methods: A review of the literature. Transfusion [print-electronic]. 2021 Jun; 61(6): 1749-56. PMID: 33797101, DOI: 10.1111/trf.16388, ISSN: 1537-2995.

Crowe EP, Goel R, Andrews J, Meyer EK, Wong TE, Sloan SR, Delaney M, Lieberman L, Cushing MM. Survey of newborn direct antiglobulin testing practice in United States and Canadian transfusion services. Transfusion [print-electronic]. 2021 Apr; 61(4): 1080-92. PMID: 33629748, DOI: 10.1111/trf.16335, ISSN: 1537-2995.

Walker SC, Andrews J. Novel Blood Component Therapies in the Pediatric Setting. Clin Lab Med [print-electronic]. 2021 Mar; 41(1): 153-71. PMID: 33494883, PII: S0272-2712(20)30091-3, DOI: 10.1016/j.cll.2020.10.010, ISSN: 1557-9832.

Adkins BD, Andrews J, Sharma D, Hughes C, Kassim AA, Eichbaum Q. Low rates of anti-recipient isohemagglutinins in ABO incompatible hematopoietic stem cell transplants. Transfus Apher Sci [print-electronic]. 2021 Feb; 60(1): 102965. PMID: 33127310, PII: S1473-0502(20)30281-0, DOI: 10.1016/j.transci.2020.102965, ISSN: 1473-0502.

Sharma D, Ogbenna AA, Kassim A, Andrews J. Transfusion support in patients with sickle cell disease. Semin Hematol [print-electronic]. 2020 Apr; 57(2): 39-50. PMID: 32892842, PII: S0037-1963(20)30025-1, DOI: 10.1053/j.seminhematol.2020.07.007, ISSN: 1532-8686.

Downey LA, Andrews J, Hedlin H, Kamra K, McKenzie ED, Hanley FL, Williams GD, Guzzetta NA. Fibrinogen Concentrate as an Alternative to Cryoprecipitate in a Postcardiopulmonary Transfusion Algorithm in Infants Undergoing Cardiac Surgery: A Prospective Randomized Controlled Trial. Anesth Analg. 2020 Mar; 130(3): 740-51. PMID: 31490252, DOI: 10.1213/ANE.0000000000004384, ISSN: 1526-7598.

Miller J, Cai W, Andrews J, Narla A. A case series of pediatric patients with direct antiglobulin test negative autoimmune hemolytic anemia. Transfusion [print-electronic]. 2019 Aug; 59(8): 2528-31. PMID: 31111963, DOI: 10.1111/trf.15350, ISSN: 1537-2995.

Andrews J. The time has come to mitigate the risk of lead exposure from blood transfusions. Pediatr Res [print-electronic]. 2019 Jan; 85(1): 7-8. PMID: 30397277, PII: 10.1038/s41390-018-0218-2, DOI: 10.1038/s41390-018-0218-2, ISSN: 1530-0447.

Metcalf RA, Khan J, Andrews J, Mayock D, Billimoria Z, Pagano MB. Severe ABO Hemolytic Disease of the Newborn Requiring Exchange Transfusion. J. Pediatr. Hematol. Oncol [print-electronic]. 2018 Jul 7/23/2018; PMID: 30044350, DOI: 10.1097/MPH.0000000000001248, ISSN: 1536-3678.

Hunter G, Blankenburg R, Andrews J, Stevenson T. An Unusual Case of Abdominal Pain and Hyponatremia in a 16-Year-Old Girl With Disordered Eating. Pediatrics [print-electronic]. 2018 Jan; 141(1): PMID: 29208727, PII: peds.2017-0291, DOI: 10.1542/peds.2017-0291, ISSN: 1098-4275.

Fontaine MJ, Shih H, Schubert R, Wong W, Andrews J, Jeng M, Tirouvanziam R. Leukocyte and plasma activation profiles in chronically transfused patients with a history of allergic reactions. Transfusion [print-electronic]. 2017 Nov; 57(11): 2639-48. PMID: 28880378, DOI: 10.1111/trf.14275, ISSN: 1537-2995.

Andrews J. Evidence for a more restrictive hematocrit trigger for neonates with respiratory failure requiring ECMO [editorial]. Transfusion. 2017 Sep; 57(9): 2063-5. PMID: 28868738, DOI: 10.1111/trf.14254, ISSN: 1537-2995.

Panigrahi AK, Yeaton-Massey A, Bakhtary S, Andrews J, Lyell DJ, Butwick AJ, Goodnough LT. A Standardized Approach for Transfusion Medicine Support in Patients With Morbidly Adherent Placenta. Anesth. Analg. 2017 Aug; 125(2): 603-8. PMID: 28640786, DOI: 10.1213/ANE.0000000000002050, ISSN: 1526-7598.

Andrews J, Winkler AM. Challenges with Navigating the Precarious Hemostatic Balance during Extracorporeal Life Support: Implications for Coagulation and Transfusion Management. Transfus Med Rev [print-electronic]. 2016 Oct; 30(4): 223-9. PMID: 27543261, PII: S0887-7963(16)30043-8, DOI: 10.1016/j.tmrv.2016.07.005, ISSN: 1532-9496.

Metcalf RA, Bakhtary S, Goodnough LT, Andrews J. Clinical Pattern in Hypotensive Transfusion Reactions. Anesth. Analg. 2016 Aug; 123(2): 268-73. PMID: 27284999, DOI: 10.1213/ANE.0000000000001387, ISSN: 1526-7598.

Bakhtary S, Gikas A, Glader B, Andrews J. Anti-Mur as the most likely cause of mild hemolytic disease of the newborn. Transfusion [print-electronic]. 2016 May; 56(5): 1182-4. PMID: 26996653, DOI: 10.1111/trf.13552, ISSN: 1537-2995.

McCarthy CE, O'Brien M, Andrews J, Zoland JM, Macasiray E, Wong W, Lo C, Glader B, Tamaresis J, Jeng M. Updated analysis: central venous access device infection rates in an expanded cohort of paediatric patients with severe haemophilia receiving prophylactic recombinant tissue plasminogen activator. Haemophilia [print-electronic]. 2016 Jan; 22(1): 81-6. PMID: 26248602, DOI: 10.1111/hae.12772, ISSN: 1365-2516.

Shah N, Andrews J, Goodnough LT. Transfusions for anemia in adult and pediatric patients with malignancies. Blood Rev [print-electronic]. 2015 Sep; 29(5): 291-9. PMID: 25796130, PII: S0268-960X(15)00016-8, DOI: 10.1016/j.blre.2015.02.001, ISSN: 1532-1681.

Hughes J, McNaughton J, Andrews J, George T, Bergero C, Pyke-Grimm K, Galel SA, Gonzalez C, Goodnough LT, Fontaine MJ. Infusion pump-mediated mechanical hemolysis in pediatric patients. Ann. Clin. Lab. Sci. 2015; 45(2): 140-7. PMID: 25887866, PII: 45/2/140, ISSN: 1550-8080.

Bartholomew F, Aftandilian C, Andrews J, Gutierrez K, Luna-Fineman S, Jeng M. Evaluation of febrile, nonneutropenic pediatric oncology patients with central venous catheters who are not given empiric antibiotics. J. Pediatr [print-electronic]. 2015 Jan; 166(1): 157-62. PMID: 25444524, PII: S0022-3476(14)00822-1, DOI: 10.1016/j.jpeds.2014.09.008, ISSN: 1097-6833.

Wallenstein MB, Arain YH, Birnie KL, Andrews J, Palma JP, Benitz WE, Chock VY. Red blood cell transfusion is not associated with necrotizing enterocolitis: a review of consecutive transfusions in a tertiary neonatal intensive care unit. J. Pediatr [print-electronic]. 2014 Oct; 165(4): 678-82. PMID: 25039042, PMCID: PMC4845907, PII: S0022-3476(14)00529-0, DOI: 10.1016/j.jpeds.2014.06.012, ISSN: 1097-6833.

McClain CM, Hughes J, Andrews JC, Blackburn J, Sephel S, France D, Viele M, Goodnough LT, Young PP. Blood ordering from the operating room: turnaround time as a quality indicator. Transfusion [print-electronic]. 2013 Jan; 53(1): 41-8. PMID: 22536922, DOI: 10.1111/j.1537-2995.2012.03670.x, ISSN: 1537-2995.