Kathryn Eby Beckermann, Ph.D., M.D.

Instructor

katy.beckermann@vanderbilt.edu
Faculty Appointments
Instructor in Medicine
Education
M.D., Vanderbilt University, Nashville, TennesseePh.D., Biochemistry, Vanderbilt University, Nashville, TennesseeB.S., Biology, Southwestern University , Georgetown, Texas
Publications
Rasmussen ML, Kline LA, Park KP, Ortolano NA, Romero-Morales AI, Anthony CC, Beckermann KE, Gama V. A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells. Stem Cell Reports [print-electronic]. 2018 Mar 3/13/2018; 10(3): 684-92. PMID: 29429957, PMCID: PMC5918190, PII: S2213-6711(18)30031-6, DOI: 10.1016/j.stemcr.2018.01.005, ISSN: 2213-6711.

McQuade JL, Daniel CR, Hess KR, Mak C, Wang DY, Rai RR, Park JJ, Haydu LE, Spencer C, Wongchenko M, Lane S, Lee DY, Kaper M, McKean M, Beckermann KE, Rubinstein SM, Rooney I, Musib L, Budha N, Hsu J, Nowicki TS, Avila A, Haas T, Puligandla M, Lee S, Fang S, Wargo JA, Gershenwald JE, Lee JE, Hwu P, Chapman PB, Sosman JA, Schadendorf D, Grob JJ, Flaherty KT, Walker D, Yan Y, McKenna E, Legos JJ, Carlino MS, Ribas A, Kirkwood JM, Long GV, Johnson DB, Menzies AM, Davies MA. Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. Lancet Oncol [print-electronic]. 2018 Mar; 19(3): 310-22. PMID: 29449192, PMCID: PMC5840029, PII: S1470-2045(18)30078-0, DOI: 10.1016/S1470-2045(18)30078-0, ISSN: 1474-5488.

Beckermann KE, Sharma D, Chaturvedi S, Msaouel P, Abboud MR, Allory Y, Bourdeaut F, Calderaro J, de Cubas AA, Derebail VK, Hong AL, Naik RP, Malouf GG, Mullen EA, Reuter VE, Roberts CWM, Walker CL, Wood CG, DeBaun MR, Van Poppel H, Tannir NM, Rathmell WK. Renal Medullary Carcinoma: Establishing Standards in Practice. J Oncol Pract. 2017 Jul; 13(7): 414-21. PMID: 28697319, PMCID: PMC5508447, DOI: 10.1200/JOP.2017.020909, ISSN: 1935-469X.

Siska PJ, Beckermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, Irish JM, Rathmell WK, Rathmell JC. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. JCI Insight [print-electronic]. 2017 Jun 6/15/2017; 2(12): PMID: 28614802, PMCID: PMC5470888, PII: 93411, DOI: 10.1172/jci.insight.93411, ISSN: 2379-3708.

Beckermann KE, Dudzinski SO, Rathmell JC. Dysfunctional T cell metabolism in the tumor microenvironment. Cytokine Growth Factor Rev [print-electronic]. 2017 Jun; 35: 7-14. PMID: 28456467, PMCID: PMC5710836, PII: S1359-6101(17)30052-7, DOI: 10.1016/j.cytogfr.2017.04.003, ISSN: 1879-0305.

Siska PJ, Beckermann KE, Rathmell WK, Haake SM. Strategies to overcome therapeutic resistance in renal cell carcinoma. Urol. Oncol [print-electronic]. 2017 Mar; 35(3): 102-10. PMID: 28089416, PMCID: PMC5318278, PII: S1078-1439(16)30409-4, DOI: 10.1016/j.urolonc.2016.12.002, ISSN: 1873-2496.

Shiuan E, Beckermann KE, Ozgun A, Kelly C, McKean M, McQuade J, Thompson MA, Puzanov I, Greer JP, Rapisuwon S, Postow M, Davies MA, Eroglu Z, Johnson D. Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy. J Immunother Cancer. 2017; 5: 8. PMID: 28239462, PMCID: PMC5319013, PII: 210, DOI: 10.1186/s40425-017-0210-0, ISSN: 2051-1426.

Beckermann KE, Jolly PC, Kim JY, Bordeaux J, Puzanov I, Rathmell WK, Johnson DB. Clinical and immunologic correlates of response to PD-1 blockade in a patient with metastatic renal medullary carcinoma. J Immunother Cancer. 2017; 5: 1. PMID: 28105368, PMCID: PMC5240268, PII: 206, DOI: 10.1186/s40425-016-0206-1, ISSN: 2051-1426.

Beckermann KE, Johnson DB, Sosman JA. PD-1/PD-L1 blockade in renal cell cancer. Expert Rev Clin Immunol [print-electronic]. 2017 Jan; 13(1): 77-84. PMID: 27426025, PMCID: PMC5555220, DOI: 10.1080/1744666X.2016.1214575, ISSN: 1744-8409.

Siska PJ, Kim B, Ji X, Hoeksema MD, Massion PP, Beckermann KE, Wu J, Chi JT, Hong J, Rathmell JC. Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. J. Immunol. Methods [print-electronic]. 2016 Nov; 438: 51-8. PMID: 27594594, PMCID: PMC5065394, PII: S0022-1759(16)30188-0, DOI: 10.1016/j.jim.2016.08.013, ISSN: 1872-7905.

Iams W, Beckermann KE, Neff AT, Mayer IA, Abramson VG. Thrombotic microangiopathy during docetaxel, trastuzumab, and carboplatin chemotherapy for early-stage HER2+ breast cancer: a case report. Med. Oncol [print-electronic]. 2013; 30(2): 568. PMID: 23564368, PMCID: PMC3774143, DOI: 10.1007/s12032-013-0568-x, ISSN: 1559-131X.