Faculty Appointments
Assistant Professor of Medicine
Assistant Professor of Molecular Physiology & BiophysicsAssistant Professor of Pathology, Microbiology and Immunology
Education
M.D., Medicine, University of Virginia, Charlottesville, VirginiaPh.D., Molecular Physiology and Biophysics, University of Virginia, Charlottesville, VirginiaM.S., Biological Sciences, University of Virginia, Charlottesville, VirginiaB.A., Biological Chemistry, Wellesley College, Wellesley, Massachusetts
Office Address
2220 Pierce Ave
Nashville, TN 37232
Nashville, TN 37232
Research Description
I am a board-certified cardiologist, NIH-funded physician-scientist, and Fellow of the American Heart Association whose work bridges clinical cardiology, vascular biology and translational immunology. My career has been shaped by a commitment to understanding the inflammatory mechanisms that drive cardiovascular disease with the goal of transforming those discoveries into strategies that will improve patient care.
Currently, I serve as an Assistant Professor of Medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center, with secondary appointments in Molecular Physiology and Biophysics and in Pathology, Microbiology, and Immunology at Vanderbilt University. My research program focuses on inflammation resolution, myeloid biology, trained immunity, and atherosclerosis, with the goal of identifying new therapeutic pathways to target residual cardiovascular risk.
As a clinician, I care for patients through the inpatient cardiology consult service as well as the Vanderbilt Lipid Clinic. These roles have afforded me the privilege of participating in several clinical trials focused on lipid management, lipoprotein(a), familial lipid disorders, and implementation strategies to improve management of cholesterol after hospitalization for atherosclerotic cardiovascular disease.
Through my complementary roles as both a clinician and a basic-translational research scientist, I aim to accelerate scientific discovery, develop the next generation of physician-scientists, and improve the lives of patients with cardiovascular disease.
Currently, I serve as an Assistant Professor of Medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center, with secondary appointments in Molecular Physiology and Biophysics and in Pathology, Microbiology, and Immunology at Vanderbilt University. My research program focuses on inflammation resolution, myeloid biology, trained immunity, and atherosclerosis, with the goal of identifying new therapeutic pathways to target residual cardiovascular risk.
As a clinician, I care for patients through the inpatient cardiology consult service as well as the Vanderbilt Lipid Clinic. These roles have afforded me the privilege of participating in several clinical trials focused on lipid management, lipoprotein(a), familial lipid disorders, and implementation strategies to improve management of cholesterol after hospitalization for atherosclerotic cardiovascular disease.
Through my complementary roles as both a clinician and a basic-translational research scientist, I aim to accelerate scientific discovery, develop the next generation of physician-scientists, and improve the lives of patients with cardiovascular disease.
Clinical Description
Dr. Doran is part of the Vanderbilt Lipid Clinic and the inpatient consult service in the Division of Cardiovascular Medicine.
Research Keywords
atherosclerosis, inflammation resolution, immunology, immunity, macrophage, lymphocyte, monocyte, innate immune memory, trained immunity
Clinical Research Keywords
cholesterol, lipids, familial hypercholesterolemia, statin intolerance
Publications
Wassenaar JW, Smart CD, Fehrenbach DJ, Shuey MM, Sangowdar P, Zhong L, Miller FJ, Wells QS, Huang S, Collins SP, Storrow AB, Miller KF, Gupta DK, Doran AC, Madhur MS. Galectin-1 Is a Marker but Not a Mediator of Heart Failure With Preserved Ejection Fraction. Hypertension [print-electronic]. 2026 Apr; 83(4): e26006. PMID: 41614247, PMCID: PMC12879785, DOI: 10.1161/HYPERTENSIONAHA.125.26006, ISSN: 1524-4563.
Dean ED, Desine S, Smith HM, Doran AC, Mosley JD, Calcutt MW, Ferguson JF. The Response of Alpha-Aminoadipic Acid (2-AAA) to Short Term Lysine Ingestion in Healthy Individuals. Endocrinol Diabetes Metab. 2026 Mar; 9(2): e70168. PMID: 41721626, PMCID: PMC12928091, DOI: 10.1002/edm2.70168, ISSN: 2398-9238.
Hope E, Gonzalez AL, Norman LS, Smith HC, Wassenaar JW, Vickers KC, Brown JD, Doran AC. Trained immunity: new paradigm in the immunological memory of cardiovascular disease. Immunohorizons. 2026 Feb 2/17/2026; 10(SI): PMID: 41723637, PMCID: PMC12925321, PII: 8494498, DOI: 10.1093/immhor/vlag008, ISSN: 2573-7732.
Reyna DE, Davis E, Salina ACG, Blackman A, Martinez-Barricarte R, Doran A, Serezani CH. Hyperglycemia promotes maladaptive Dectin-1 signaling and impairs skin antifungal host defense. BioRxiv. 2026 Feb 2/13/2026; PMID: 41726973, PMCID: PMC12918998, PII: 2026.02.11.705431, DOI: 10.64898/2026.02.11.705431, ISSN: 2692-8205.
Banerjee DR, Hasenour CM, Rahim M, Bednarski TK, Doran AC, Jacobson DA, Young JD. Sarco/Endoplasmic Reticulum Ca2+ ATPase Activation Shifts Cardiac Fuel Preference Without Impairing Cardiac Function in Obese Mice. J Am Heart Assoc [print-electronic]. 2026 Jan 1/6/2026; 15(1): e042505. PMID: 41404731, PMCID: PMC12909024, DOI: 10.1161/JAHA.125.042505, ISSN: 2047-9980.
Semler EM, Michell DL, Kingsley PJ, Ramirez MA, Massick C, Castleberry M, Doran AC, Carr JJ, Marnett L, Sheng Q, Linton MF, Vickers KC. Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis. Atherosclerosis [print-electronic]. 2026 Jan; 412: 120584. PMID: 41380623, PMCID: PMC12990388, PII: S0021-9150(25)01482-0, DOI: 10.1016/j.atherosclerosis.2025.120584, ISSN: 1879-1484.
Gonzalez AL, Youwakim CM, Leake BF, Fuller KK, Rahman SMJ, Dungan MM, Gu K, Bonin JL, Cavnar AB, Michell DL, Davison LM, Cutchins C, Chu YE, Yuan S, Yurdagul A, Traylor JG, Orr AW, Kohutek ZA, Linton MF, MacNamara KC, Ferrell PB, Vickers KC, Madhur MS, Brown JD, Doran AC. Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis. Arterioscler Thromb Vasc Biol [print-electronic]. 2025 Jul; 45(7): e286-e306-e306. PMID: 40336480, PMCID: PMC12197841, DOI: 10.1161/ATVBAHA.125.322530, ISSN: 1524-4636.
Jeppesen DK, Sanchez ZC, Kelley NM, Hayes JB, Ambroise J, Koory EN, Krystofiak E, Taneja N, Zhang Q, Dungan MM, Perkins OL, Tyska MJ, Knapik EW, Dean KM, Doran AC, Coffey RJ, Burnette DT. Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties. Nat Cell Biol [print-electronic]. 2025 Mar; 27(3): 438-48. PMID: 39984653, PMCID: PMC11906356, PII: 10.1038/s41556-025-01621-0, DOI: 10.1038/s41556-025-01621-0, ISSN: 1476-4679.
Kohutek ZA, Caslin HL, Fehrenbach DJ, Heimlich JB, Brown JD, Madhur MS, Ferrell PB, Doran AC. Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential. Circ Res [print-electronic]. 2025 Jan 1/31/2025; 136(3): 325-53. PMID: 39883790, PMCID: PMC11790260, DOI: 10.1161/CIRCRESAHA.124.323778, ISSN: 1524-4571.
Wassenaar JW, Smart CD, Fehrenbach DJ, Agrawal V, Dungan MM, Fortune NL, Zhong L, Hemnes AR, Peebles RS, Miller FJ, Doran AC, Madhur MS. Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease. JACC Basic Transl Sci. 2025 Jan; 10(1): 107-9. PMID: 39958476, PMCID: PMC11830270, PII: S2452-302X(24)00345-0, DOI: 10.1016/j.jacbts.2024.09.006, ISSN: 2452-302X.
Semler EM, Michell DL, Kingsley PJ, Massick C, Ramirez MA, Castleberry MA, Doran AC, Carr JJ, Marnett LJ, Sheng Q, Linton MF, Vickers KC. Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis. BioRxiv. 2024 Dec 12/20/2024; PMID: 39763941, PMCID: PMC11702621, PII: 2024.12.19.628772, DOI: 10.1101/2024.12.19.628772, ISSN: 2692-8205.
Antonetti OR, Desine S, Smith HM, Robles ME, McDonald E, Ovide G, Wang C, Dean ED, Doran AC, Calcutt MW, Huang S, Brown JD, Silver HJ, Ferguson JF. The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA). Nutr Metab Cardiovasc Dis [print-electronic]. 2024 Jul; 34(7): 1712-20. PMID: 38658223, PMCID: PMC11188583, PII: S0939-4753(24)00111-X, DOI: 10.1016/j.numecd.2024.03.009, ISSN: 1590-3729.
Pimenov L, Gonzalez AL, Doran AC, Knapp S. Correction: Same name, different game?-How ontogeny shapes classical monocyte phenotypes. Genes Immun. 2024 Jun; 25(3): 264. PMID: 38594516, PMCID: PMC11178489, PII: 10.1038/s41435-024-00269-4, DOI: 10.1038/s41435-024-00269-4, ISSN: 1476-5470.
Obare LM, Bonami RH, Doran AC, Wanjalla CN. B cells and atherosclerosis: A HIV perspective. J Cell Physiol [print-electronic]. 2024 Jun; 239(6): e31270. PMID: 38651687, PMCID: PMC11209796, DOI: 10.1002/jcp.31270, ISSN: 1097-4652.
Gonzalez AL, Dungan MM, Smart CD, Madhur MS, Doran AC. Inflammation Resolution in the Cardiovascular System: Arterial Hypertension, Atherosclerosis, and Ischemic Heart Disease. Antioxid Redox Signal [print-electronic]. 2024 Feb; 40(4-6): 292-316. PMID: 37125445, PMCID: PMC11071112, DOI: 10.1089/ars.2023.0284, ISSN: 1557-7716.
Pimenov L, Gonzalez AL, Doran AC, Knapp S. Same name, different game?-How ontogeny shapes classical monocyte phenotypes. Genes Immun [print-electronic]. 2024 Feb; 25(1): 1-3. PMID: 38245600, PMCID: PMC10873193, PII: 10.1038/s41435-023-00248-1, DOI: 10.1038/s41435-023-00248-1, ISSN: 1476-5470.
Smart CD, Fehrenbach DJ, Wassenaar JW, Agrawal V, Fortune NL, Dixon DD, Cottam MA, Hasty AH, Hemnes AR, Doran AC, Gupta DK, Madhur MS. Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure. Cardiovasc Res. 2023 Oct 10/24/2023; 119(13): 2312-28. PMID: 37314125, PMCID: PMC10597637, PII: 7197670, DOI: 10.1093/cvr/cvad093, ISSN: 1755-3245.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie K, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem Biol [print-electronic]. 2023 Aug 8/18/2023; 18(8): 1891-904. PMID: 37531659, PMCID: PMC10443532, DOI: 10.1021/acschembio.3c00401, ISSN: 1554-8937.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals. MedRxiv. 2023 Jun 6/6/2023; PMID: 37333170, PMCID: PMC10274998, PII: 2023.06.05.23290990, DOI: 10.1101/2023.06.05.23290990.
Burkett JB, Doran AC, Gannon M. Harnessing prostaglandin E2 signaling to ameliorate autoimmunity. Trends Immunol [print-electronic]. 2023 Mar; 44(3): 162-71. PMID: 36707339, PMCID: PMC9975049, PII: S1471-4906(23)00004-2, DOI: 10.1016/j.it.2023.01.004, ISSN: 1471-4981.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie KP, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. BioRxiv. 2023 Feb 2/28/2023; PMID: 36747693, PMCID: PMC9900783, PII: 2023.01.25.525554, DOI: 10.1101/2023.01.25.525554, ISSN: 2692-8205.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals. Front Endocrinol (Lausanne). 2023; 14: 1122391. PMID: 37745703, PMCID: PMC10513411, DOI: 10.3389/fendo.2023.1122391, ISSN: 1664-2392.
Allen RM, Michell DL, Cavnar AB, Zhu W, Makhijani N, Contreras DM, Raby CA, Semler EM, DeJulius C, Castleberry M, Zhang Y, Ramirez-Solano M, Zhao S, Duvall C, Doran AC, Sheng Q, Linton MF, Vickers KC. LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8. Nat Cell Biol [print-electronic]. 2022 Dec; 24(12): 1701-13. PMID: 36474072, PMCID: PMC10609361, PII: 10.1038/s41556-022-01030-7, DOI: 10.1038/s41556-022-01030-7, ISSN: 1476-4679.
Doran AC. Inflammation Resolution: Implications for Atherosclerosis. Circ Res [print-electronic]. 2022 Jan 1/7/2022; 130(1): 130-48. PMID: 34995137, PMCID: PMC8842990, DOI: 10.1161/CIRCRESAHA.121.319822, ISSN: 1524-4571.
Zarrow JE, Tian J, Dutter B, Kim K, Doran AC, Sulikowski GA, Davies SS. Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog. J Lipid Res [print-electronic]. 2022 Jan; 63(1): 100156. PMID: 34843683, PMCID: PMC8953660, PII: S0022-2275(21)00139-5, DOI: 10.1016/j.jlr.2021.100156, ISSN: 1539-7262.
Vacante F, Rodor J, Lalwani MK, Mahmoud AD, Bennett M, De Pace AL, Miller E, Van Kuijk K, de Bruijn J, Gijbels M, Williams TC, Clark MB, Scanlon JP, Doran AC, Montgomery R, Newby DE, Giacca M, O'Carroll D, Hadoke PWF, Denby L, Sluimer JC, Baker AH. CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice. Circ Res [print-electronic]. 2021 Apr 4/30/2021; 128(9): 1258-75. PMID: 33622045, PMCID: PMC7610708, DOI: 10.1161/CIRCRESAHA.120.318688, ISSN: 1524-4571.
Doran AC, Terry JG, Carr JJ, Linton MF. Statins and Atherosclerotic Lesion Microcalcification: A New Mechanism for Plaque Stability? [editorial]. Arterioscler Thromb Vasc Biol [print-electronic]. 2021 Apr; 41(4): 1306-8. PMID: 33760629, PMCID: PMC8011331, DOI: 10.1161/ATVBAHA.121.315949, ISSN: 1524-4636.
Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. SiRNA nanoparticles targeting CaMKII¿ in lesional macrophages improve atherosclerotic plaque stability in mice. Sci Transl Med. 2020 Jul 7/22/2020; 12(553): PMID: 32718990, PMCID: PMC7476570, PII: 12/553/eaay1063, DOI: 10.1126/scitranslmed.aay1063, ISSN: 1946-6242.
Doran AC, Yurdagul A, Tabas I. Efferocytosis in health and disease. Nat. Rev. Immunol [print-electronic]. 2019 Dec 12/10/2019; PMID: 31822793, PII: 10.1038/s41577-019-0240-6, DOI: 10.1038/s41577-019-0240-6, ISSN: 1474-1741.
Liu T, Xiang A, Peng T, Doran AC, Tracey KJ, Barnes BJ, Tabas I, Son M, Diamond B. HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2019 Nov 11/12/2019; 116(46): 23254-63. PMID: 31570601, PII: 1907490116, DOI: 10.1073/pnas.1907490116, ISSN: 1091-6490.
Thomas DG, Doran AC, Fotakis P, Westerterp M, Antonson P, Jiang H, Jiang XC, Gustafsson JÅ, Tabas I, Tall AR. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Rep. 2018 Dec 12/26/2018; 25(13): 3774-3785.e4. PMID: 30590048, PMCID: PMC6446575, PII: S2211-1247(18)31906-5, DOI: 10.1016/j.celrep.2018.11.100, ISSN: 2211-1247.
Moore KJ, Koplev S, Fisher EA, Tabas I, Björkegren JLM, Doran AC, Kovacic JC. Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2). J. Am. Coll. Cardiol. 2018 Oct 10/30/2018; 72(18): 2181-97. PMID: 30360827, PMCID: PMC6522246, PII: S0735-1097(18)38295-0, DOI: 10.1016/j.jacc.2018.08.2147, ISSN: 1558-3597.
Proto JD, Doran AC, Gusarova G, Yurdagul A, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J, Tabas I. Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity [print-electronic]. 2018 Oct 10/16/2018; 49(4): 666-677.e6. PMID: 30291029, PMCID: PMC6192849, PII: S1074-7613(18)30335-2, DOI: 10.1016/j.immuni.2018.07.015, ISSN: 1097-4180.
Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB, Tabas I. MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Sci Signal. 2018 Sep 9/25/2018; 11(549): PMID: 30254055, PMCID: PMC6171110, PII: 11/549/eaar3721, DOI: 10.1126/scisignal.aar3721, ISSN: 1937-9145.
Kasikara C, Doran AC, Cai B, Tabas I. The role of non-resolving inflammation in atherosclerosis. J. Clin. Invest [print-electronic]. 2018 Jul 7/2/2018; 128(7): 2713-23. PMID: 30108191, PMCID: PMC6025992, PII: 97950, DOI: 10.1172/JCI97950, ISSN: 1558-8238.
Proto JD, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang YG, Tabas I. Hypercholesterolemia induces T cell expansion in humanized immune mice. J. Clin. Invest [print-electronic]. 2018 Jun 6/1/2018; 128(6): 2370-5. PMID: 29708512, PMCID: PMC5983331, PII: 97785, DOI: 10.1172/JCI97785, ISSN: 1558-8238.
Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. CAMKII¿ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J. Clin. Invest [print-electronic]. 2017 Nov 11/1/2017; 127(11): 4075-89. PMID: 28972541, PMCID: PMC5663361, PII: 94735, DOI: 10.1172/JCI94735, ISSN: 1558-8238.
Cai B, Thorp EB, Doran AC, Sansbury BE, Daemen MJ, Dorweiler B, Spite M, Fredman G, Tabas I. MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis. J. Clin. Invest [print-electronic]. 2017 Feb 2/1/2017; 127(2): 564-8. PMID: 28067670, PMCID: PMC5272169, PII: 90520, DOI: 10.1172/JCI90520, ISSN: 1558-8238.
Yurdagul A, Doran AC, Cai B, Fredman G, Tabas IA. Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis. Front Cardiovasc Med. 2017; 4: 86. PMID: 29379788, PMCID: PMC5770804, DOI: 10.3389/fcvm.2017.00086, ISSN: 2297-055X.
Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2016 Jun 6/7/2016; 113(23): 6526-31. PMID: 27199481, PMCID: PMC4988577, PII: 1524292113, DOI: 10.1073/pnas.1524292113, ISSN: 1091-6490.
Colombo PC, Doran AC, Onat D, Wong KY, Ahmad M, Sabbah HN, Demmer RT. Venous congestion, endothelial and neurohormonal activation in acute decompensated heart failure: cause or effect?. Curr Heart Fail Rep. 2015 Jun; 12(3): 215-22. PMID: 25740404, PMCID: PMC4426008, DOI: 10.1007/s11897-015-0254-8, ISSN: 1546-9549.
Lipinski MJ, Campbell KA, Duong SQ, Welch TJ, Garmey JC, Doran AC, Skaflen MD, Oldham SN, Kelly KA, McNamara CA. Loss of Id3 increases VCAM-1 expression, macrophage accumulation, and atherogenesis in Ldlr-/- mice. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2012 Dec; 32(12): 2855-61. PMID: 23042815, PMCID: PMC3509414, PII: ATVBAHA.112.300352, DOI: 10.1161/ATVBAHA.112.300352, ISSN: 1524-4636.
Campbell KA, Lipinski MJ, Doran AC, Skaflen MD, Fuster V, McNamara CA. Lymphocytes and the adventitial immune response in atherosclerosis. Circ. Res. 2012 Mar 3/16/2012; 110(6): 889-900. PMID: 22427326, PMCID: PMC3373006, PII: 110/6/889, DOI: 10.1161/CIRCRESAHA.111.263186, ISSN: 1524-4571.
Cutchins A, Harmon DB, Kirby JL, Doran AC, Oldham SN, Skaflen M, Klibanov AL, Meller N, Keller SR, Garmey J, McNamara CA. Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2012 Feb; 32(2): 317-24. PMID: 22075252, PMCID: PMC3262109, PII: ATVBAHA.111.234856, DOI: 10.1161/ATVBAHA.111.234856, ISSN: 1524-4636.
Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, McNamara CA. B-cell aortic homing and atheroprotection depend on Id3. Circ. Res [print-electronic]. 2012 Jan 1/6/2012; 110(1): e1-12. PMID: 22034493, PMCID: PMC3253259, PII: CIRCRESAHA.111.256438, DOI: 10.1161/CIRCRESAHA.111.256438, ISSN: 1524-4571.
Bagavant H, Scindia Y, Nackiewicz D, Nandula SR, Doran A, Cutchins A, Oldham S, Deshmukh U, McNamara C. Deficiency of a transcriptional regulator, inhibitor of differentiation 3, induces glomerulonephritis in apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease. Am. J. Pathol [print-electronic]. 2011 Aug; 179(2): 651-60. PMID: 21801865, PMCID: PMC3157169, PII: S0002-9440(11)00437-8, DOI: 10.1016/j.ajpath.2011.04.029, ISSN: 1525-2191.
Lipinski MJ, Perry HM, Doran AC, Oldham SN, McNamara CA. Comment on "Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis" [letter]. J. Immunol. 2011 Jan 1/1/2011; 186(1): 4; author reply 6. PMID: 21172871, PII: 186/1/4, DOI: 10.4049/jimmunol.1090119, ISSN: 1550-6606.
Deliri H, Meller N, Kadakkal A, Malhotra R, Brewster J, Doran AC, Pei H, Oldham SN, Skaflen MD, Garmey JC, McNamara CA. Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition, and neointimal formation in response to carotid injury. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2011 Jan; 31(1): 110-6. PMID: 20947825, PII: ATVBAHA.110.212068, DOI: 10.1161/ATVBAHA.110.212068, ISSN: 1524-4636.
Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ. Res [print-electronic]. 2010 Sep 9/17/2010; 107(6): 737-46. PMID: 20651288, PMCID: PMC2941538, PII: CIRCRESAHA.109.215715, DOI: 10.1161/CIRCRESAHA.109.215715, ISSN: 1524-4571.
Doran AC, Lehtinen AB, Meller N, Lipinski MJ, Slayton RP, Oldham SN, Skaflen MD, Yeboah J, Rich SS, Bowden DW, McNamara CA. Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans. Circ. Res [print-electronic]. 2010 Apr 4/16/2010; 106(7): 1303-11. PMID: 20185798, PMCID: PMC2860382, PII: CIRCRESAHA.109.210294, DOI: 10.1161/CIRCRESAHA.109.210294, ISSN: 1524-4571.
Doran AC, Meller N, Cutchins A, Deliri H, Slayton RP, Oldham SN, Kim JB, Keller SR, McNamara CA. The helix-loop-helix factors Id3 and E47 are novel regulators of adiponectin. Circ. Res [print-electronic]. 2008 Sep 9/12/2008; 103(6): 624-34. PMID: 18669923, PMCID: PMC2746666, PII: CIRCRESAHA.108.175893, DOI: 10.1161/CIRCRESAHA.108.175893, ISSN: 1524-4571.
Doran AC, Meller N, McNamara CA. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2008 May; 28(5): 812-9. PMID: 18276911, PMCID: PMC2734458, PII: ATVBAHA.107.159327, DOI: 10.1161/ATVBAHA.107.159327, ISSN: 1524-4636.
Doran AC, Wan YP, Kopin AS, Beinborn M. Established theory of radiation-induced decay is not generalizable to Bolton-Hunter labeled peptides. Biochem. Pharmacol. 2003 May 5/1/2003; 65(9): 1515-20. PMID: 12732364, PII: S0006295203001035, ISSN: 0006-2952.
Dean ED, Desine S, Smith HM, Doran AC, Mosley JD, Calcutt MW, Ferguson JF. The Response of Alpha-Aminoadipic Acid (2-AAA) to Short Term Lysine Ingestion in Healthy Individuals. Endocrinol Diabetes Metab. 2026 Mar; 9(2): e70168. PMID: 41721626, PMCID: PMC12928091, DOI: 10.1002/edm2.70168, ISSN: 2398-9238.
Hope E, Gonzalez AL, Norman LS, Smith HC, Wassenaar JW, Vickers KC, Brown JD, Doran AC. Trained immunity: new paradigm in the immunological memory of cardiovascular disease. Immunohorizons. 2026 Feb 2/17/2026; 10(SI): PMID: 41723637, PMCID: PMC12925321, PII: 8494498, DOI: 10.1093/immhor/vlag008, ISSN: 2573-7732.
Reyna DE, Davis E, Salina ACG, Blackman A, Martinez-Barricarte R, Doran A, Serezani CH. Hyperglycemia promotes maladaptive Dectin-1 signaling and impairs skin antifungal host defense. BioRxiv. 2026 Feb 2/13/2026; PMID: 41726973, PMCID: PMC12918998, PII: 2026.02.11.705431, DOI: 10.64898/2026.02.11.705431, ISSN: 2692-8205.
Banerjee DR, Hasenour CM, Rahim M, Bednarski TK, Doran AC, Jacobson DA, Young JD. Sarco/Endoplasmic Reticulum Ca2+ ATPase Activation Shifts Cardiac Fuel Preference Without Impairing Cardiac Function in Obese Mice. J Am Heart Assoc [print-electronic]. 2026 Jan 1/6/2026; 15(1): e042505. PMID: 41404731, PMCID: PMC12909024, DOI: 10.1161/JAHA.125.042505, ISSN: 2047-9980.
Semler EM, Michell DL, Kingsley PJ, Ramirez MA, Massick C, Castleberry M, Doran AC, Carr JJ, Marnett L, Sheng Q, Linton MF, Vickers KC. Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis. Atherosclerosis [print-electronic]. 2026 Jan; 412: 120584. PMID: 41380623, PMCID: PMC12990388, PII: S0021-9150(25)01482-0, DOI: 10.1016/j.atherosclerosis.2025.120584, ISSN: 1879-1484.
Gonzalez AL, Youwakim CM, Leake BF, Fuller KK, Rahman SMJ, Dungan MM, Gu K, Bonin JL, Cavnar AB, Michell DL, Davison LM, Cutchins C, Chu YE, Yuan S, Yurdagul A, Traylor JG, Orr AW, Kohutek ZA, Linton MF, MacNamara KC, Ferrell PB, Vickers KC, Madhur MS, Brown JD, Doran AC. Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis. Arterioscler Thromb Vasc Biol [print-electronic]. 2025 Jul; 45(7): e286-e306-e306. PMID: 40336480, PMCID: PMC12197841, DOI: 10.1161/ATVBAHA.125.322530, ISSN: 1524-4636.
Jeppesen DK, Sanchez ZC, Kelley NM, Hayes JB, Ambroise J, Koory EN, Krystofiak E, Taneja N, Zhang Q, Dungan MM, Perkins OL, Tyska MJ, Knapik EW, Dean KM, Doran AC, Coffey RJ, Burnette DT. Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties. Nat Cell Biol [print-electronic]. 2025 Mar; 27(3): 438-48. PMID: 39984653, PMCID: PMC11906356, PII: 10.1038/s41556-025-01621-0, DOI: 10.1038/s41556-025-01621-0, ISSN: 1476-4679.
Kohutek ZA, Caslin HL, Fehrenbach DJ, Heimlich JB, Brown JD, Madhur MS, Ferrell PB, Doran AC. Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential. Circ Res [print-electronic]. 2025 Jan 1/31/2025; 136(3): 325-53. PMID: 39883790, PMCID: PMC11790260, DOI: 10.1161/CIRCRESAHA.124.323778, ISSN: 1524-4571.
Wassenaar JW, Smart CD, Fehrenbach DJ, Agrawal V, Dungan MM, Fortune NL, Zhong L, Hemnes AR, Peebles RS, Miller FJ, Doran AC, Madhur MS. Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease. JACC Basic Transl Sci. 2025 Jan; 10(1): 107-9. PMID: 39958476, PMCID: PMC11830270, PII: S2452-302X(24)00345-0, DOI: 10.1016/j.jacbts.2024.09.006, ISSN: 2452-302X.
Semler EM, Michell DL, Kingsley PJ, Massick C, Ramirez MA, Castleberry MA, Doran AC, Carr JJ, Marnett LJ, Sheng Q, Linton MF, Vickers KC. Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis. BioRxiv. 2024 Dec 12/20/2024; PMID: 39763941, PMCID: PMC11702621, PII: 2024.12.19.628772, DOI: 10.1101/2024.12.19.628772, ISSN: 2692-8205.
Antonetti OR, Desine S, Smith HM, Robles ME, McDonald E, Ovide G, Wang C, Dean ED, Doran AC, Calcutt MW, Huang S, Brown JD, Silver HJ, Ferguson JF. The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA). Nutr Metab Cardiovasc Dis [print-electronic]. 2024 Jul; 34(7): 1712-20. PMID: 38658223, PMCID: PMC11188583, PII: S0939-4753(24)00111-X, DOI: 10.1016/j.numecd.2024.03.009, ISSN: 1590-3729.
Pimenov L, Gonzalez AL, Doran AC, Knapp S. Correction: Same name, different game?-How ontogeny shapes classical monocyte phenotypes. Genes Immun. 2024 Jun; 25(3): 264. PMID: 38594516, PMCID: PMC11178489, PII: 10.1038/s41435-024-00269-4, DOI: 10.1038/s41435-024-00269-4, ISSN: 1476-5470.
Obare LM, Bonami RH, Doran AC, Wanjalla CN. B cells and atherosclerosis: A HIV perspective. J Cell Physiol [print-electronic]. 2024 Jun; 239(6): e31270. PMID: 38651687, PMCID: PMC11209796, DOI: 10.1002/jcp.31270, ISSN: 1097-4652.
Gonzalez AL, Dungan MM, Smart CD, Madhur MS, Doran AC. Inflammation Resolution in the Cardiovascular System: Arterial Hypertension, Atherosclerosis, and Ischemic Heart Disease. Antioxid Redox Signal [print-electronic]. 2024 Feb; 40(4-6): 292-316. PMID: 37125445, PMCID: PMC11071112, DOI: 10.1089/ars.2023.0284, ISSN: 1557-7716.
Pimenov L, Gonzalez AL, Doran AC, Knapp S. Same name, different game?-How ontogeny shapes classical monocyte phenotypes. Genes Immun [print-electronic]. 2024 Feb; 25(1): 1-3. PMID: 38245600, PMCID: PMC10873193, PII: 10.1038/s41435-023-00248-1, DOI: 10.1038/s41435-023-00248-1, ISSN: 1476-5470.
Smart CD, Fehrenbach DJ, Wassenaar JW, Agrawal V, Fortune NL, Dixon DD, Cottam MA, Hasty AH, Hemnes AR, Doran AC, Gupta DK, Madhur MS. Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure. Cardiovasc Res. 2023 Oct 10/24/2023; 119(13): 2312-28. PMID: 37314125, PMCID: PMC10597637, PII: 7197670, DOI: 10.1093/cvr/cvad093, ISSN: 1755-3245.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie K, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem Biol [print-electronic]. 2023 Aug 8/18/2023; 18(8): 1891-904. PMID: 37531659, PMCID: PMC10443532, DOI: 10.1021/acschembio.3c00401, ISSN: 1554-8937.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals. MedRxiv. 2023 Jun 6/6/2023; PMID: 37333170, PMCID: PMC10274998, PII: 2023.06.05.23290990, DOI: 10.1101/2023.06.05.23290990.
Burkett JB, Doran AC, Gannon M. Harnessing prostaglandin E2 signaling to ameliorate autoimmunity. Trends Immunol [print-electronic]. 2023 Mar; 44(3): 162-71. PMID: 36707339, PMCID: PMC9975049, PII: S1471-4906(23)00004-2, DOI: 10.1016/j.it.2023.01.004, ISSN: 1471-4981.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie KP, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. BioRxiv. 2023 Feb 2/28/2023; PMID: 36747693, PMCID: PMC9900783, PII: 2023.01.25.525554, DOI: 10.1101/2023.01.25.525554, ISSN: 2692-8205.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals. Front Endocrinol (Lausanne). 2023; 14: 1122391. PMID: 37745703, PMCID: PMC10513411, DOI: 10.3389/fendo.2023.1122391, ISSN: 1664-2392.
Allen RM, Michell DL, Cavnar AB, Zhu W, Makhijani N, Contreras DM, Raby CA, Semler EM, DeJulius C, Castleberry M, Zhang Y, Ramirez-Solano M, Zhao S, Duvall C, Doran AC, Sheng Q, Linton MF, Vickers KC. LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8. Nat Cell Biol [print-electronic]. 2022 Dec; 24(12): 1701-13. PMID: 36474072, PMCID: PMC10609361, PII: 10.1038/s41556-022-01030-7, DOI: 10.1038/s41556-022-01030-7, ISSN: 1476-4679.
Doran AC. Inflammation Resolution: Implications for Atherosclerosis. Circ Res [print-electronic]. 2022 Jan 1/7/2022; 130(1): 130-48. PMID: 34995137, PMCID: PMC8842990, DOI: 10.1161/CIRCRESAHA.121.319822, ISSN: 1524-4571.
Zarrow JE, Tian J, Dutter B, Kim K, Doran AC, Sulikowski GA, Davies SS. Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog. J Lipid Res [print-electronic]. 2022 Jan; 63(1): 100156. PMID: 34843683, PMCID: PMC8953660, PII: S0022-2275(21)00139-5, DOI: 10.1016/j.jlr.2021.100156, ISSN: 1539-7262.
Vacante F, Rodor J, Lalwani MK, Mahmoud AD, Bennett M, De Pace AL, Miller E, Van Kuijk K, de Bruijn J, Gijbels M, Williams TC, Clark MB, Scanlon JP, Doran AC, Montgomery R, Newby DE, Giacca M, O'Carroll D, Hadoke PWF, Denby L, Sluimer JC, Baker AH. CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice. Circ Res [print-electronic]. 2021 Apr 4/30/2021; 128(9): 1258-75. PMID: 33622045, PMCID: PMC7610708, DOI: 10.1161/CIRCRESAHA.120.318688, ISSN: 1524-4571.
Doran AC, Terry JG, Carr JJ, Linton MF. Statins and Atherosclerotic Lesion Microcalcification: A New Mechanism for Plaque Stability? [editorial]. Arterioscler Thromb Vasc Biol [print-electronic]. 2021 Apr; 41(4): 1306-8. PMID: 33760629, PMCID: PMC8011331, DOI: 10.1161/ATVBAHA.121.315949, ISSN: 1524-4636.
Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. SiRNA nanoparticles targeting CaMKII¿ in lesional macrophages improve atherosclerotic plaque stability in mice. Sci Transl Med. 2020 Jul 7/22/2020; 12(553): PMID: 32718990, PMCID: PMC7476570, PII: 12/553/eaay1063, DOI: 10.1126/scitranslmed.aay1063, ISSN: 1946-6242.
Doran AC, Yurdagul A, Tabas I. Efferocytosis in health and disease. Nat. Rev. Immunol [print-electronic]. 2019 Dec 12/10/2019; PMID: 31822793, PII: 10.1038/s41577-019-0240-6, DOI: 10.1038/s41577-019-0240-6, ISSN: 1474-1741.
Liu T, Xiang A, Peng T, Doran AC, Tracey KJ, Barnes BJ, Tabas I, Son M, Diamond B. HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2019 Nov 11/12/2019; 116(46): 23254-63. PMID: 31570601, PII: 1907490116, DOI: 10.1073/pnas.1907490116, ISSN: 1091-6490.
Thomas DG, Doran AC, Fotakis P, Westerterp M, Antonson P, Jiang H, Jiang XC, Gustafsson JÅ, Tabas I, Tall AR. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Rep. 2018 Dec 12/26/2018; 25(13): 3774-3785.e4. PMID: 30590048, PMCID: PMC6446575, PII: S2211-1247(18)31906-5, DOI: 10.1016/j.celrep.2018.11.100, ISSN: 2211-1247.
Moore KJ, Koplev S, Fisher EA, Tabas I, Björkegren JLM, Doran AC, Kovacic JC. Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2). J. Am. Coll. Cardiol. 2018 Oct 10/30/2018; 72(18): 2181-97. PMID: 30360827, PMCID: PMC6522246, PII: S0735-1097(18)38295-0, DOI: 10.1016/j.jacc.2018.08.2147, ISSN: 1558-3597.
Proto JD, Doran AC, Gusarova G, Yurdagul A, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J, Tabas I. Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity [print-electronic]. 2018 Oct 10/16/2018; 49(4): 666-677.e6. PMID: 30291029, PMCID: PMC6192849, PII: S1074-7613(18)30335-2, DOI: 10.1016/j.immuni.2018.07.015, ISSN: 1097-4180.
Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB, Tabas I. MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Sci Signal. 2018 Sep 9/25/2018; 11(549): PMID: 30254055, PMCID: PMC6171110, PII: 11/549/eaar3721, DOI: 10.1126/scisignal.aar3721, ISSN: 1937-9145.
Kasikara C, Doran AC, Cai B, Tabas I. The role of non-resolving inflammation in atherosclerosis. J. Clin. Invest [print-electronic]. 2018 Jul 7/2/2018; 128(7): 2713-23. PMID: 30108191, PMCID: PMC6025992, PII: 97950, DOI: 10.1172/JCI97950, ISSN: 1558-8238.
Proto JD, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang YG, Tabas I. Hypercholesterolemia induces T cell expansion in humanized immune mice. J. Clin. Invest [print-electronic]. 2018 Jun 6/1/2018; 128(6): 2370-5. PMID: 29708512, PMCID: PMC5983331, PII: 97785, DOI: 10.1172/JCI97785, ISSN: 1558-8238.
Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. CAMKII¿ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J. Clin. Invest [print-electronic]. 2017 Nov 11/1/2017; 127(11): 4075-89. PMID: 28972541, PMCID: PMC5663361, PII: 94735, DOI: 10.1172/JCI94735, ISSN: 1558-8238.
Cai B, Thorp EB, Doran AC, Sansbury BE, Daemen MJ, Dorweiler B, Spite M, Fredman G, Tabas I. MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis. J. Clin. Invest [print-electronic]. 2017 Feb 2/1/2017; 127(2): 564-8. PMID: 28067670, PMCID: PMC5272169, PII: 90520, DOI: 10.1172/JCI90520, ISSN: 1558-8238.
Yurdagul A, Doran AC, Cai B, Fredman G, Tabas IA. Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis. Front Cardiovasc Med. 2017; 4: 86. PMID: 29379788, PMCID: PMC5770804, DOI: 10.3389/fcvm.2017.00086, ISSN: 2297-055X.
Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2016 Jun 6/7/2016; 113(23): 6526-31. PMID: 27199481, PMCID: PMC4988577, PII: 1524292113, DOI: 10.1073/pnas.1524292113, ISSN: 1091-6490.
Colombo PC, Doran AC, Onat D, Wong KY, Ahmad M, Sabbah HN, Demmer RT. Venous congestion, endothelial and neurohormonal activation in acute decompensated heart failure: cause or effect?. Curr Heart Fail Rep. 2015 Jun; 12(3): 215-22. PMID: 25740404, PMCID: PMC4426008, DOI: 10.1007/s11897-015-0254-8, ISSN: 1546-9549.
Lipinski MJ, Campbell KA, Duong SQ, Welch TJ, Garmey JC, Doran AC, Skaflen MD, Oldham SN, Kelly KA, McNamara CA. Loss of Id3 increases VCAM-1 expression, macrophage accumulation, and atherogenesis in Ldlr-/- mice. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2012 Dec; 32(12): 2855-61. PMID: 23042815, PMCID: PMC3509414, PII: ATVBAHA.112.300352, DOI: 10.1161/ATVBAHA.112.300352, ISSN: 1524-4636.
Campbell KA, Lipinski MJ, Doran AC, Skaflen MD, Fuster V, McNamara CA. Lymphocytes and the adventitial immune response in atherosclerosis. Circ. Res. 2012 Mar 3/16/2012; 110(6): 889-900. PMID: 22427326, PMCID: PMC3373006, PII: 110/6/889, DOI: 10.1161/CIRCRESAHA.111.263186, ISSN: 1524-4571.
Cutchins A, Harmon DB, Kirby JL, Doran AC, Oldham SN, Skaflen M, Klibanov AL, Meller N, Keller SR, Garmey J, McNamara CA. Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2012 Feb; 32(2): 317-24. PMID: 22075252, PMCID: PMC3262109, PII: ATVBAHA.111.234856, DOI: 10.1161/ATVBAHA.111.234856, ISSN: 1524-4636.
Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, McNamara CA. B-cell aortic homing and atheroprotection depend on Id3. Circ. Res [print-electronic]. 2012 Jan 1/6/2012; 110(1): e1-12. PMID: 22034493, PMCID: PMC3253259, PII: CIRCRESAHA.111.256438, DOI: 10.1161/CIRCRESAHA.111.256438, ISSN: 1524-4571.
Bagavant H, Scindia Y, Nackiewicz D, Nandula SR, Doran A, Cutchins A, Oldham S, Deshmukh U, McNamara C. Deficiency of a transcriptional regulator, inhibitor of differentiation 3, induces glomerulonephritis in apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease. Am. J. Pathol [print-electronic]. 2011 Aug; 179(2): 651-60. PMID: 21801865, PMCID: PMC3157169, PII: S0002-9440(11)00437-8, DOI: 10.1016/j.ajpath.2011.04.029, ISSN: 1525-2191.
Lipinski MJ, Perry HM, Doran AC, Oldham SN, McNamara CA. Comment on "Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis" [letter]. J. Immunol. 2011 Jan 1/1/2011; 186(1): 4; author reply 6. PMID: 21172871, PII: 186/1/4, DOI: 10.4049/jimmunol.1090119, ISSN: 1550-6606.
Deliri H, Meller N, Kadakkal A, Malhotra R, Brewster J, Doran AC, Pei H, Oldham SN, Skaflen MD, Garmey JC, McNamara CA. Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition, and neointimal formation in response to carotid injury. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2011 Jan; 31(1): 110-6. PMID: 20947825, PII: ATVBAHA.110.212068, DOI: 10.1161/ATVBAHA.110.212068, ISSN: 1524-4636.
Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ. Res [print-electronic]. 2010 Sep 9/17/2010; 107(6): 737-46. PMID: 20651288, PMCID: PMC2941538, PII: CIRCRESAHA.109.215715, DOI: 10.1161/CIRCRESAHA.109.215715, ISSN: 1524-4571.
Doran AC, Lehtinen AB, Meller N, Lipinski MJ, Slayton RP, Oldham SN, Skaflen MD, Yeboah J, Rich SS, Bowden DW, McNamara CA. Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans. Circ. Res [print-electronic]. 2010 Apr 4/16/2010; 106(7): 1303-11. PMID: 20185798, PMCID: PMC2860382, PII: CIRCRESAHA.109.210294, DOI: 10.1161/CIRCRESAHA.109.210294, ISSN: 1524-4571.
Doran AC, Meller N, Cutchins A, Deliri H, Slayton RP, Oldham SN, Kim JB, Keller SR, McNamara CA. The helix-loop-helix factors Id3 and E47 are novel regulators of adiponectin. Circ. Res [print-electronic]. 2008 Sep 9/12/2008; 103(6): 624-34. PMID: 18669923, PMCID: PMC2746666, PII: CIRCRESAHA.108.175893, DOI: 10.1161/CIRCRESAHA.108.175893, ISSN: 1524-4571.
Doran AC, Meller N, McNamara CA. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler. Thromb. Vasc. Biol [print-electronic]. 2008 May; 28(5): 812-9. PMID: 18276911, PMCID: PMC2734458, PII: ATVBAHA.107.159327, DOI: 10.1161/ATVBAHA.107.159327, ISSN: 1524-4636.
Doran AC, Wan YP, Kopin AS, Beinborn M. Established theory of radiation-induced decay is not generalizable to Bolton-Hunter labeled peptides. Biochem. Pharmacol. 2003 May 5/1/2003; 65(9): 1515-20. PMID: 12732364, PII: S0006295203001035, ISSN: 0006-2952.