Faculty Appointments
Research Assistant Professor of Medicine
Education
Ph.D., Developmental Biology, Fudan University, Shanghai, ChinaB.S., Biological Sciences , Huazhong Agricultural University, Wuhan, China
Publications
Shi F. Understanding the roles of salt-inducible kinases in cardiometabolic disease. Front Physiol. 2024; 15: 1426244. PMID: 39081779, PMCID: PMC11286596, PII: 1426244, DOI: 10.3389/fphys.2024.1426244, ISSN: 1664-042X.
Jia B, Hasse A, Shi F, Collins S. Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor. PLoS One. 2023 Nov 11/2/2023; 18(11): e0293636. PMID: 37917630, PII: PONE-D-23-27751, DOI: 10.1371/journal.pone.0293636, ISSN: 1932-6203.
Ceddia RP, Zurawski Z, Thompson Gray A, Adegboye F, McDonald-Boyer A, Shi F, Liu D, Maldonado J, Feng J, Li Y, Alford S, Ayala JE, McGuinness OP, Collins S, Hamm HE. Gß¿-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity. J Clin Invest [print-electronic]. 2023 Aug 8/10/2023; PMID: 37561580, PII: 160617, DOI: 10.1172/JCI160617, ISSN: 1558-8238.
Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Türk C, Krüger M, Collins S. Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning. Mol Metab [print-electronic]. 2023 Aug; 74: 101753. PMID: 37321371, PMCID: PMC10319839, PII: S2212-8778(23)00087-X, DOI: 10.1016/j.molmet.2023.101753, ISSN: 2212-8778.
Shi F, Collins S. Regulation of mTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease. Int J Mol Sci. 2023 Jul 7/15/2023; 24(14): PMID: 37511253, PMCID: PMC10380887, PII: ijms241411497, DOI: 10.3390/ijms241411497, ISSN: 1422-0067.
Liu D, Ceddia RP, Zhang W, Shi F, Fang H, Collins S. Discovery of another mechanism for the inhibition of particulate guanylyl cyclases by the natriuretic peptide clearance receptor. Proc Natl Acad Sci U S A [print-electronic]. 2023 Jul 7/11/2023; 120(28): e2307882120. PMID: 37399424, PMCID: PMC10334801, DOI: 10.1073/pnas.2307882120, ISSN: 1091-6490.
Ceddia RP, Liu D, Shi F, Crowder MK, Mishra S, Kass DA, Collins S. Increased Energy Expenditure and Protection From Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9. Diabetes [print-electronic]. 2021 Dec; 70(12): 2823-36. PMID: 34620617, PMCID: PMC8660992, PII: db21-0100, DOI: 10.2337/db21-0100, ISSN: 1939-327X.
Shi F, Simandi Z, Nagy L, Collins S. Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPAR¿ via long-range distal enhancers. J Biol Chem [print-electronic]. 2021 Aug; 297(2): 100941. PMID: 34245781, PMCID: PMC8326739, PII: S0021-9258(21)00741-9, DOI: 10.1016/j.jbc.2021.100941, ISSN: 1083-351X.
Agrawal V, Fortune N, Yu S, Fuentes J, Shi F, Nichols D, Gleaves L, Poovey E, Wang TJ, Brittain EL, Collins S, West JD, Hemnes AR. Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension. Pulm Circ. 2019; 9(4): 2045894019878599. PMID: 31903184, PMCID: PMC6923530, PII: 10.1177_2045894019895452, DOI: 10.1177/2045894019895452, ISSN: 2045-8932.
Shi F, Collins S. Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective. Horm Mol Biol Clin Investig. 2017 Sep 9/26/2017; 31(2): PMID: 28949928, PII: /j/hmbci.ahead-of-print/hmbci-2017-0062/hmbci-2017-0062.xml, DOI: 10.1515/hmbci-2017-0062, ISSN: 1868-1891.
Wu W, Shi F, Liu D, Ceddia RP, Gaffin R, Wei W, Fang H, Lewandowski ED, Collins S. Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance. Sci Signal. 2017 Jul 7/25/2017; 10(489): PMID: 28743802, PMCID: PMC7418652, PII: 10/489/eaam6870, DOI: 10.1126/scisignal.aam6870, ISSN: 1937-9145.
Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, Wu X. A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet [print-electronic]. 2014 Jul 7/15/2014; 23(14): 3792-800. PMID: 24565867, PII: ddu092, DOI: 10.1093/hmg/ddu092, ISSN: 1460-2083.
Jia B, Hasse A, Shi F, Collins S. Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor. PLoS One. 2023 Nov 11/2/2023; 18(11): e0293636. PMID: 37917630, PII: PONE-D-23-27751, DOI: 10.1371/journal.pone.0293636, ISSN: 1932-6203.
Ceddia RP, Zurawski Z, Thompson Gray A, Adegboye F, McDonald-Boyer A, Shi F, Liu D, Maldonado J, Feng J, Li Y, Alford S, Ayala JE, McGuinness OP, Collins S, Hamm HE. Gß¿-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity. J Clin Invest [print-electronic]. 2023 Aug 8/10/2023; PMID: 37561580, PII: 160617, DOI: 10.1172/JCI160617, ISSN: 1558-8238.
Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Türk C, Krüger M, Collins S. Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning. Mol Metab [print-electronic]. 2023 Aug; 74: 101753. PMID: 37321371, PMCID: PMC10319839, PII: S2212-8778(23)00087-X, DOI: 10.1016/j.molmet.2023.101753, ISSN: 2212-8778.
Shi F, Collins S. Regulation of mTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease. Int J Mol Sci. 2023 Jul 7/15/2023; 24(14): PMID: 37511253, PMCID: PMC10380887, PII: ijms241411497, DOI: 10.3390/ijms241411497, ISSN: 1422-0067.
Liu D, Ceddia RP, Zhang W, Shi F, Fang H, Collins S. Discovery of another mechanism for the inhibition of particulate guanylyl cyclases by the natriuretic peptide clearance receptor. Proc Natl Acad Sci U S A [print-electronic]. 2023 Jul 7/11/2023; 120(28): e2307882120. PMID: 37399424, PMCID: PMC10334801, DOI: 10.1073/pnas.2307882120, ISSN: 1091-6490.
Ceddia RP, Liu D, Shi F, Crowder MK, Mishra S, Kass DA, Collins S. Increased Energy Expenditure and Protection From Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9. Diabetes [print-electronic]. 2021 Dec; 70(12): 2823-36. PMID: 34620617, PMCID: PMC8660992, PII: db21-0100, DOI: 10.2337/db21-0100, ISSN: 1939-327X.
Shi F, Simandi Z, Nagy L, Collins S. Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPAR¿ via long-range distal enhancers. J Biol Chem [print-electronic]. 2021 Aug; 297(2): 100941. PMID: 34245781, PMCID: PMC8326739, PII: S0021-9258(21)00741-9, DOI: 10.1016/j.jbc.2021.100941, ISSN: 1083-351X.
Agrawal V, Fortune N, Yu S, Fuentes J, Shi F, Nichols D, Gleaves L, Poovey E, Wang TJ, Brittain EL, Collins S, West JD, Hemnes AR. Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension. Pulm Circ. 2019; 9(4): 2045894019878599. PMID: 31903184, PMCID: PMC6923530, PII: 10.1177_2045894019895452, DOI: 10.1177/2045894019895452, ISSN: 2045-8932.
Shi F, Collins S. Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective. Horm Mol Biol Clin Investig. 2017 Sep 9/26/2017; 31(2): PMID: 28949928, PII: /j/hmbci.ahead-of-print/hmbci-2017-0062/hmbci-2017-0062.xml, DOI: 10.1515/hmbci-2017-0062, ISSN: 1868-1891.
Wu W, Shi F, Liu D, Ceddia RP, Gaffin R, Wei W, Fang H, Lewandowski ED, Collins S. Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance. Sci Signal. 2017 Jul 7/25/2017; 10(489): PMID: 28743802, PMCID: PMC7418652, PII: 10/489/eaam6870, DOI: 10.1126/scisignal.aam6870, ISSN: 1937-9145.
Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, Wu X. A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet [print-electronic]. 2014 Jul 7/15/2014; 23(14): 3792-800. PMID: 24565867, PII: ddu092, DOI: 10.1093/hmg/ddu092, ISSN: 1460-2083.