Faculty Appointments
Assistant Professor of Pharmacology
Education
Ph.D., Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North CarolinaB.A., Psychology, State University of New York, Binghamton, New York
Research Description
A major focus of the lab is to understand the neural mechanisms of individual differences in decision making – that is, why do behavioral responses vary even when given the same experience. For example, although a large portion of the population will be exposed to alcohol, only some will go on to develop an alcohol use disorder. We develop behavioral procedures in rodents to model these phenomena, allowing us to determine the pre-existing differences that may contribute to individual differences as well as how they change with experience. By combining these models with various recording and manipulation techniques we dissect the circuitry of maladaptive decision making.
Research Keywords
motivation, learning, addiction, imaging, electrochemistry, optics
Publications
Farahbakhsh ZZ, Holleran KM, Sens JP, Fordahl SC, Mauterer MI, López AJ, Cuzon Carlson VC, Kiraly DD, Grant KA, Jones SR, Siciliano CA. Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking. Nat Commun. 2025 Feb 2/25/2025; 16(1): 1944. PMID: 39994195, PMCID: PMC11850823, PII: 10.1038/s41467-025-56715-y, DOI: 10.1038/s41467-025-56715-y, ISSN: 2041-1723.
Nolan SO, Melugin PR, Erickson KR, Adams WR, Farahbakhsh ZZ, Mcgonigle CE, Kwon MH, Costa VD, Hackett TA, Cuzon Carlson VC, Constantinidis C, Lapish CC, Grant KA, Siciliano CA. Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits. Curr Biol [print-electronic]. 2025 Jan 1/20/2025; 35(2): 431-443.e4-443.e4. PMID: 39765226, PMCID: PMC11832050, PII: S0960-9822(24)01636-1, DOI: 10.1016/j.cub.2024.11.069, ISSN: 1879-0445.
Farahbakhsh ZZ, Song K, Branthwaite HE, Erickson KR, Mukerjee S, Nolan SO, Siciliano CA. Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice. Neuropsychopharmacology [print-electronic]. 2023 May; 48(6): 857-68. PMID: 36804487, PMCID: PMC10156709, PII: 10.1038/s41386-023-01547-x, DOI: 10.1038/s41386-023-01547-x, ISSN: 1740-634X.
Brown AR, Branthwaite HE, Farahbakhsh ZZ, Mukerjee S, Melugin PR, Song K, Noamany H, Siciliano CA. Structured tracking of alcohol reinforcement (STAR) for basic and translational alcohol research. Mol Psychiatry [print-electronic]. 2023 Apr; 28(4): 1585-98. PMID: 36849824, PMCID: PMC10208967, PII: 10.1038/s41380-023-01994-4, DOI: 10.1038/s41380-023-01994-4, ISSN: 1476-5578.
Farahbakhsh ZZ, Siciliano CA. Pavlovian-conditioned opioid tolerance. Sci Adv [print-electronic]. 2023 Feb 2/10/2023; 9(6): eadg6086. PMID: 36753539, PMCID: PMC9908010, DOI: 10.1126/sciadv.adg6086, ISSN: 2375-2548.
Mejaes J, Desai D, Siciliano CA, Barker DJ. Practical opinions for new fiber photometry users to obtain rigorous recordings and avoid pitfalls. Pharmacol Biochem Behav [print-electronic]. 2022 Nov; 221: 173488. PMID: 36370828, PMCID: PMC9753223, PII: S0091-3057(22)00167-8, DOI: 10.1016/j.pbb.2022.173488, ISSN: 1873-5177.
Li H, Namburi P, Olson JM, Borio M, Lemieux ME, Beyeler A, Calhoon GG, Hitora-Imamura N, Coley AA, Libster A, Bal A, Jin X, Wang H, Jia C, Choudhury SR, Shi X, Felix-Ortiz AC, de la Fuente V, Barth VP, King HO, Izadmehr EM, Revanna JS, Batra K, Fischer KB, Keyes LR, Padilla-Coreano N, Siciliano CA, McCullough KM, Wichmann R, Ressler KJ, Fiete IR, Zhang F, Li Y, Tye KM. Neurotensin orchestrates valence assignment in the amygdala. Nature [print-electronic]. 2022 Aug; 608(7923): 586-92. PMID: 35859170, PMCID: PMC9583860, PII: 10.1038/s41586-022-04964-y, DOI: 10.1038/s41586-022-04964-y, ISSN: 1476-4687.
Kutlu MG, Zachry JE, Melugin PR, Tat J, Cajigas S, Isiktas AU, Patel DD, Siciliano CA, Schoenbaum G, Sharpe MJ, Calipari ES. Dopamine signaling in the nucleus accumbens core mediates latent inhibition. Nat Neurosci [print-electronic]. 2022 Aug; 25(8): 1071-81. PMID: 35902648, PMCID: PMC9768922, PII: 10.1038/s41593-022-01126-1, DOI: 10.1038/s41593-022-01126-1, ISSN: 1546-1726.
Everett AC, Graul BE, Ronström JW, Robinson JK, Watts DB, España RA, Siciliano CA, Yorgason JT. Effectiveness and Relationship between Biased and Unbiased Measures of Dopamine Release and Clearance. ACS Chem Neurosci [print-electronic]. 2022 May 5/18/2022; 13(10): 1534-48. PMID: 35482592, PMCID: PMC10763521, DOI: 10.1021/acschemneuro.2c00033, ISSN: 1948-7193.
Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ. Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons. Neuron [print-electronic]. 2022 Mar 3/16/2022; 110(6): 1068-1083.e5-1083.e5. PMID: 35045338, PMCID: PMC8930582, PII: S0896-6273(21)01044-8, DOI: 10.1016/j.neuron.2021.12.027, ISSN: 1097-4199.
Brundage JN, Mason CP, Wadsworth HA, Finuf CS, Nelson JJ, Ronström PJW, Jones SR, Siciliano CA, Steffensen SC, Yorgason JT. Regional and sex differences in spontaneous striatal dopamine transmission. J Neurochem [print-electronic]. 2022 Mar; 160(6): 598-612. PMID: 34265080, PMCID: PMC10044475, DOI: 10.1111/jnc.15473, ISSN: 1471-4159.
Leach AC, Pitts EG, Siciliano CA, Ferris MJ. A7 nicotinic acetylcholine receptor modulation of accumbal dopamine release covaries with novelty seeking. Eur J Neurosci [print-electronic]. 2022 Mar; 55(5): 1162-73. PMID: 35141983, PMCID: PMC9586210, DOI: 10.1111/ejn.15620, ISSN: 1460-9568.
Egervari G, Siciliano CA, Whiteley EL, Ron D. Alcohol and the brain: from genes to circuits. Trends Neurosci [print-electronic]. 2021 Dec; 44(12): 1004-15. PMID: 34702580, PMCID: PMC8616825, PII: S0166-2236(21)00187-9, DOI: 10.1016/j.tins.2021.09.006, ISSN: 1878-108X.
Kutlu MG, Zachry JE, Melugin PR, Cajigas SA, Chevee MF, Kelly SJ, Kutlu B, Tian L, Siciliano CA, Calipari ES. Dopamine release in the nucleus accumbens core signals perceived saliency. Curr Biol [print-electronic]. 2021 Nov 11/8/2021; 31(21): 4748-4761.e8-4761.e8. PMID: 34529938, PMCID: PMC9084920, PII: S0960-9822(21)01188-X, DOI: 10.1016/j.cub.2021.08.052, ISSN: 1879-0445.
López AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. An optimized procedure for robust volitional cocaine intake in mice. Exp Clin Psychopharmacol [print-electronic]. 2021 Aug; 29(4): 319-33. PMID: 32658535, PMCID: PMC7890946, PII: 2020-50172-001, DOI: 10.1037/pha0000399, ISSN: 1936-2293.
Winters ND, Bedse G, Astafyev AA, Patrick TA, Altemus M, Morgan AJ, Mukerjee S, Johnson KD, Mahajan VR, Uddin MJ, Kingsley PJ, Centanni SW, Siciliano CA, Samuels DC, Marnett LJ, Winder DG, Patel S. Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models. J Clin Invest [print-electronic]. 2021 Jul 7/22/2021; 131(17): PMID: 34292886, PMCID: PMC8409586, PII: e146861, DOI: 10.1172/JCI146861, ISSN: 1558-8238.
Farahbakhsh ZZ, Siciliano CA. Neurobiology of novelty seeking. Science. 2021 May 5/14/2021; 372(6543): 684-5. PMID: 33986168, PII: 372/6543/684, DOI: 10.1126/science.abi7270, ISSN: 1095-9203.
Zachry JE, Nolan SO, Brady LJ, Kelly SJ, Siciliano CA, Calipari ES. Sex differences in dopamine release regulation in the striatum. Neuropsychopharmacology [print-electronic]. 2021 Feb; 46(3): 491-9. PMID: 33318634, PMCID: PMC8027008, PII: 10.1038/s41386-020-00915-1, DOI: 10.1038/s41386-020-00915-1, ISSN: 1740-634X.
Melugin PR, Nolan SO, Siciliano CA. Bidirectional causality between addiction and cognitive deficits. Int Rev Neurobiol [print-electronic]. 2021; 157: 371-407. PMID: 33648674, PMCID: PMC8566632, PII: S0074-7742(20)30146-X, DOI: 10.1016/bs.irn.2020.11.001, ISSN: 2162-5514.
Lewis AS, Calipari ES, Siciliano CA. Toward Standardized Guidelines for Investigating Neural Circuit Control of Behavior in Animal Research. ENeuro [electronic-print]. 2021; 8(2): PMID: 33782101, PMCID: PMC8174055, PII: ENEURO.0498-20.2021, DOI: 10.1523/ENEURO.0498-20.2021, ISSN: 2373-2822.
Nolan SO, Zachry JE, Johnson AR, Brady LJ, Siciliano CA, Calipari ES. Direct dopamine terminal regulation by local striatal microcircuitry. J Neurochem [print-electronic]. 2020 Dec; 155(5): 475-93. PMID: 32356315, PMCID: PMC7606645, DOI: 10.1111/jnc.15034, ISSN: 1471-4159.
Shemesh OA, Linghu C, Piatkevich KD, Goodwin D, Celiker OT, Gritton HJ, Romano MF, Gao R, Yu CJ, Tseng HA, Bensussen S, Narayan S, Yang CT, Freifeld L, Siciliano CA, Gupta I, Wang J, Pak N, Yoon YG, Ullmann JFP, Guner-Ataman B, Noamany H, Sheinkopf ZR, Park WM, Asano S, Keating AE, Trimmer JS, Reimer J, Tolias AS, Bear MF, Tye KM, Han X, Ahrens MB, Boyden ES. Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. Neuron [print-electronic]. 2020 Aug 8/5/2020; 107(3): 470-486.e11-486.e11. PMID: 32592656, PMCID: PMC7415598, PII: S0896-6273(20)30398-6, DOI: 10.1016/j.neuron.2020.05.029, ISSN: 1097-4199.
Kutlu MG, Zachry JE, Brady LJ, Melugin PR, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault K, Lopez AJ, Siciliano CA, Calipari ES. A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology [print-electronic]. 2020 Aug; 45(9): 1463-72. PMID: 32375157, PMCID: PMC7360782, PII: 10.1038/s41386-020-0692-1, DOI: 10.1038/s41386-020-0692-1, ISSN: 1740-634X.
López AJ, Siciliano CA, Calipari ES. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder. Handb Exp Pharmacol. 2020; 258: 231-63. PMID: 31628597, DOI: 10.1007/164_2019_257, ISSN: 0171-2004.
Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM. A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. Science. 2019 Nov 11/22/2019; 366(6468): 1008-12. PMID: 31754002, PMCID: PMC6989100, PII: 366/6468/1008, DOI: 10.1126/science.aay1186, ISSN: 1095-9203.
Siciliano CA. Capturing the complexity of sex differences requires multidimensional behavioral models. Neuropsychopharmacology [print-electronic]. 2019 Nov; 44(12): 1997-8. PMID: 31164710, PMCID: PMC6887867, PII: 10.1038/s41386-019-0424-6, DOI: 10.1038/s41386-019-0424-6, ISSN: 1740-634X.
Kutlu MG, Brady LJ, Peck EG, Hofford RS, Yorgason JT, Siciliano CA, Kiraly DD, Calipari ES. Granulocyte Colony Stimulating Factor Enhances Reward Learning through Potentiation of Mesolimbic Dopamine System Function. J Neurosci [print-electronic]. 2018 Oct 10/10/2018; 38(41): 8845-59. PMID: 30150359, PMCID: PMC6181308, PII: JNEUROSCI.1116-18.2018, DOI: 10.1523/JNEUROSCI.1116-18.2018, ISSN: 1529-2401.
Siciliano CA, Saha K, Calipari ES, Fordahl SC, Chen R, Khoshbouei H, Jones SR. Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation. J Neurosci [print-electronic]. 2018 Jan 1/10/2018; 38(2): 484-97. PMID: 29175958, PMCID: PMC5761621, PII: JNEUROSCI.2604-17.2017, DOI: 10.1523/JNEUROSCI.2604-17.2017, ISSN: 1529-2401.
Nolan SO, Melugin PR, Erickson KR, Adams WR, Farahbakhsh ZZ, Mcgonigle CE, Kwon MH, Costa VD, Hackett TA, Cuzon Carlson VC, Constantinidis C, Lapish CC, Grant KA, Siciliano CA. Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits. Curr Biol [print-electronic]. 2025 Jan 1/20/2025; 35(2): 431-443.e4-443.e4. PMID: 39765226, PMCID: PMC11832050, PII: S0960-9822(24)01636-1, DOI: 10.1016/j.cub.2024.11.069, ISSN: 1879-0445.
Farahbakhsh ZZ, Song K, Branthwaite HE, Erickson KR, Mukerjee S, Nolan SO, Siciliano CA. Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice. Neuropsychopharmacology [print-electronic]. 2023 May; 48(6): 857-68. PMID: 36804487, PMCID: PMC10156709, PII: 10.1038/s41386-023-01547-x, DOI: 10.1038/s41386-023-01547-x, ISSN: 1740-634X.
Brown AR, Branthwaite HE, Farahbakhsh ZZ, Mukerjee S, Melugin PR, Song K, Noamany H, Siciliano CA. Structured tracking of alcohol reinforcement (STAR) for basic and translational alcohol research. Mol Psychiatry [print-electronic]. 2023 Apr; 28(4): 1585-98. PMID: 36849824, PMCID: PMC10208967, PII: 10.1038/s41380-023-01994-4, DOI: 10.1038/s41380-023-01994-4, ISSN: 1476-5578.
Farahbakhsh ZZ, Siciliano CA. Pavlovian-conditioned opioid tolerance. Sci Adv [print-electronic]. 2023 Feb 2/10/2023; 9(6): eadg6086. PMID: 36753539, PMCID: PMC9908010, DOI: 10.1126/sciadv.adg6086, ISSN: 2375-2548.
Mejaes J, Desai D, Siciliano CA, Barker DJ. Practical opinions for new fiber photometry users to obtain rigorous recordings and avoid pitfalls. Pharmacol Biochem Behav [print-electronic]. 2022 Nov; 221: 173488. PMID: 36370828, PMCID: PMC9753223, PII: S0091-3057(22)00167-8, DOI: 10.1016/j.pbb.2022.173488, ISSN: 1873-5177.
Li H, Namburi P, Olson JM, Borio M, Lemieux ME, Beyeler A, Calhoon GG, Hitora-Imamura N, Coley AA, Libster A, Bal A, Jin X, Wang H, Jia C, Choudhury SR, Shi X, Felix-Ortiz AC, de la Fuente V, Barth VP, King HO, Izadmehr EM, Revanna JS, Batra K, Fischer KB, Keyes LR, Padilla-Coreano N, Siciliano CA, McCullough KM, Wichmann R, Ressler KJ, Fiete IR, Zhang F, Li Y, Tye KM. Neurotensin orchestrates valence assignment in the amygdala. Nature [print-electronic]. 2022 Aug; 608(7923): 586-92. PMID: 35859170, PMCID: PMC9583860, PII: 10.1038/s41586-022-04964-y, DOI: 10.1038/s41586-022-04964-y, ISSN: 1476-4687.
Kutlu MG, Zachry JE, Melugin PR, Tat J, Cajigas S, Isiktas AU, Patel DD, Siciliano CA, Schoenbaum G, Sharpe MJ, Calipari ES. Dopamine signaling in the nucleus accumbens core mediates latent inhibition. Nat Neurosci [print-electronic]. 2022 Aug; 25(8): 1071-81. PMID: 35902648, PMCID: PMC9768922, PII: 10.1038/s41593-022-01126-1, DOI: 10.1038/s41593-022-01126-1, ISSN: 1546-1726.
Everett AC, Graul BE, Ronström JW, Robinson JK, Watts DB, España RA, Siciliano CA, Yorgason JT. Effectiveness and Relationship between Biased and Unbiased Measures of Dopamine Release and Clearance. ACS Chem Neurosci [print-electronic]. 2022 May 5/18/2022; 13(10): 1534-48. PMID: 35482592, PMCID: PMC10763521, DOI: 10.1021/acschemneuro.2c00033, ISSN: 1948-7193.
Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ. Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons. Neuron [print-electronic]. 2022 Mar 3/16/2022; 110(6): 1068-1083.e5-1083.e5. PMID: 35045338, PMCID: PMC8930582, PII: S0896-6273(21)01044-8, DOI: 10.1016/j.neuron.2021.12.027, ISSN: 1097-4199.
Brundage JN, Mason CP, Wadsworth HA, Finuf CS, Nelson JJ, Ronström PJW, Jones SR, Siciliano CA, Steffensen SC, Yorgason JT. Regional and sex differences in spontaneous striatal dopamine transmission. J Neurochem [print-electronic]. 2022 Mar; 160(6): 598-612. PMID: 34265080, PMCID: PMC10044475, DOI: 10.1111/jnc.15473, ISSN: 1471-4159.
Leach AC, Pitts EG, Siciliano CA, Ferris MJ. A7 nicotinic acetylcholine receptor modulation of accumbal dopamine release covaries with novelty seeking. Eur J Neurosci [print-electronic]. 2022 Mar; 55(5): 1162-73. PMID: 35141983, PMCID: PMC9586210, DOI: 10.1111/ejn.15620, ISSN: 1460-9568.
Egervari G, Siciliano CA, Whiteley EL, Ron D. Alcohol and the brain: from genes to circuits. Trends Neurosci [print-electronic]. 2021 Dec; 44(12): 1004-15. PMID: 34702580, PMCID: PMC8616825, PII: S0166-2236(21)00187-9, DOI: 10.1016/j.tins.2021.09.006, ISSN: 1878-108X.
Kutlu MG, Zachry JE, Melugin PR, Cajigas SA, Chevee MF, Kelly SJ, Kutlu B, Tian L, Siciliano CA, Calipari ES. Dopamine release in the nucleus accumbens core signals perceived saliency. Curr Biol [print-electronic]. 2021 Nov 11/8/2021; 31(21): 4748-4761.e8-4761.e8. PMID: 34529938, PMCID: PMC9084920, PII: S0960-9822(21)01188-X, DOI: 10.1016/j.cub.2021.08.052, ISSN: 1879-0445.
López AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. An optimized procedure for robust volitional cocaine intake in mice. Exp Clin Psychopharmacol [print-electronic]. 2021 Aug; 29(4): 319-33. PMID: 32658535, PMCID: PMC7890946, PII: 2020-50172-001, DOI: 10.1037/pha0000399, ISSN: 1936-2293.
Winters ND, Bedse G, Astafyev AA, Patrick TA, Altemus M, Morgan AJ, Mukerjee S, Johnson KD, Mahajan VR, Uddin MJ, Kingsley PJ, Centanni SW, Siciliano CA, Samuels DC, Marnett LJ, Winder DG, Patel S. Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models. J Clin Invest [print-electronic]. 2021 Jul 7/22/2021; 131(17): PMID: 34292886, PMCID: PMC8409586, PII: e146861, DOI: 10.1172/JCI146861, ISSN: 1558-8238.
Farahbakhsh ZZ, Siciliano CA. Neurobiology of novelty seeking. Science. 2021 May 5/14/2021; 372(6543): 684-5. PMID: 33986168, PII: 372/6543/684, DOI: 10.1126/science.abi7270, ISSN: 1095-9203.
Zachry JE, Nolan SO, Brady LJ, Kelly SJ, Siciliano CA, Calipari ES. Sex differences in dopamine release regulation in the striatum. Neuropsychopharmacology [print-electronic]. 2021 Feb; 46(3): 491-9. PMID: 33318634, PMCID: PMC8027008, PII: 10.1038/s41386-020-00915-1, DOI: 10.1038/s41386-020-00915-1, ISSN: 1740-634X.
Melugin PR, Nolan SO, Siciliano CA. Bidirectional causality between addiction and cognitive deficits. Int Rev Neurobiol [print-electronic]. 2021; 157: 371-407. PMID: 33648674, PMCID: PMC8566632, PII: S0074-7742(20)30146-X, DOI: 10.1016/bs.irn.2020.11.001, ISSN: 2162-5514.
Lewis AS, Calipari ES, Siciliano CA. Toward Standardized Guidelines for Investigating Neural Circuit Control of Behavior in Animal Research. ENeuro [electronic-print]. 2021; 8(2): PMID: 33782101, PMCID: PMC8174055, PII: ENEURO.0498-20.2021, DOI: 10.1523/ENEURO.0498-20.2021, ISSN: 2373-2822.
Nolan SO, Zachry JE, Johnson AR, Brady LJ, Siciliano CA, Calipari ES. Direct dopamine terminal regulation by local striatal microcircuitry. J Neurochem [print-electronic]. 2020 Dec; 155(5): 475-93. PMID: 32356315, PMCID: PMC7606645, DOI: 10.1111/jnc.15034, ISSN: 1471-4159.
Shemesh OA, Linghu C, Piatkevich KD, Goodwin D, Celiker OT, Gritton HJ, Romano MF, Gao R, Yu CJ, Tseng HA, Bensussen S, Narayan S, Yang CT, Freifeld L, Siciliano CA, Gupta I, Wang J, Pak N, Yoon YG, Ullmann JFP, Guner-Ataman B, Noamany H, Sheinkopf ZR, Park WM, Asano S, Keating AE, Trimmer JS, Reimer J, Tolias AS, Bear MF, Tye KM, Han X, Ahrens MB, Boyden ES. Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. Neuron [print-electronic]. 2020 Aug 8/5/2020; 107(3): 470-486.e11-486.e11. PMID: 32592656, PMCID: PMC7415598, PII: S0896-6273(20)30398-6, DOI: 10.1016/j.neuron.2020.05.029, ISSN: 1097-4199.
Kutlu MG, Zachry JE, Brady LJ, Melugin PR, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault K, Lopez AJ, Siciliano CA, Calipari ES. A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology [print-electronic]. 2020 Aug; 45(9): 1463-72. PMID: 32375157, PMCID: PMC7360782, PII: 10.1038/s41386-020-0692-1, DOI: 10.1038/s41386-020-0692-1, ISSN: 1740-634X.
López AJ, Siciliano CA, Calipari ES. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder. Handb Exp Pharmacol. 2020; 258: 231-63. PMID: 31628597, DOI: 10.1007/164_2019_257, ISSN: 0171-2004.
Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM. A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. Science. 2019 Nov 11/22/2019; 366(6468): 1008-12. PMID: 31754002, PMCID: PMC6989100, PII: 366/6468/1008, DOI: 10.1126/science.aay1186, ISSN: 1095-9203.
Siciliano CA. Capturing the complexity of sex differences requires multidimensional behavioral models. Neuropsychopharmacology [print-electronic]. 2019 Nov; 44(12): 1997-8. PMID: 31164710, PMCID: PMC6887867, PII: 10.1038/s41386-019-0424-6, DOI: 10.1038/s41386-019-0424-6, ISSN: 1740-634X.
Kutlu MG, Brady LJ, Peck EG, Hofford RS, Yorgason JT, Siciliano CA, Kiraly DD, Calipari ES. Granulocyte Colony Stimulating Factor Enhances Reward Learning through Potentiation of Mesolimbic Dopamine System Function. J Neurosci [print-electronic]. 2018 Oct 10/10/2018; 38(41): 8845-59. PMID: 30150359, PMCID: PMC6181308, PII: JNEUROSCI.1116-18.2018, DOI: 10.1523/JNEUROSCI.1116-18.2018, ISSN: 1529-2401.
Siciliano CA, Saha K, Calipari ES, Fordahl SC, Chen R, Khoshbouei H, Jones SR. Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation. J Neurosci [print-electronic]. 2018 Jan 1/10/2018; 38(2): 484-97. PMID: 29175958, PMCID: PMC5761621, PII: JNEUROSCI.2604-17.2017, DOI: 10.1523/JNEUROSCI.2604-17.2017, ISSN: 1529-2401.