Faculty Appointments
Research Assistant Professor of Radiology & Radiological Sciences
Education
Ph.D., Physics, Università degli Studi di Milano, Milan, Italy
Research Description
Fatemeh Adelnia, PhD, is a physicist, imaging scientist, and Research Assistant Professor in the Department of Radiology and Radiological Sciences at Vanderbilt University Medical Center and Vanderbilt University Institute of Imaging Science (VUIIS). She earned her PhD in Physics with a focus on nuclear magnetic resonance spectroscopy at the University of Milan. Dr. Adelnia worked as a visiting researcher and postdoctoral training at multiple sites, including Paul Scherrer Institute (PSI), Radboud University Medical Center (Radboudumc), and National Institute of Health (NIH) before joining Vanderbilt University Medical Center. She completed her postdoctoral fellowship in VUIIS under the mentorship of John Gore, Ph.D. She was awarded a four-year K25 Mentored Research Scientist Career Development grant and an Alzheimer's Disease Administrative Supplements grant from the National Institute on Aging (NIA) and was promoted to Research Assistant Professor in 2022.
Publications
Wang F, Lee SY, Adelnia F, Takahashi K, Harkins KD, He L, Zu Z, Ellinger P, Grundmann M, Harris RC, Takahashi T, Gore JC. Severity of polycystic kidney disease revealed by multiparametric MRI. Magn Reson Med [print-electronic]. 2023 Sep; 90(3): 1151-65. PMID: 37093746, DOI: 10.1002/mrm.29679, ISSN: 1522-2594.
Cameron D, Reiter DA, Adelnia F, Ubaida-Mohien C, Bergeron CM, Choi S, Fishbein KW, Spencer RG, Ferrucci L. Age-related changes in human skeletal muscle microstructure and architecture assessed by diffusion-tensor magnetic resonance imaging and their association with muscle strength. Aging Cell [print-electronic]. 2023 Jul; 22(7): e13851. PMID: 37162031, PMCID: PMC10352548, DOI: 10.1111/acel.13851, ISSN: 1474-9726.
Zu Z, Adelnia F, Harkins K, Wang F, Ostenson J, Gore JC. Correction of errors in estimates of T1¿ at low spin-lock amplitudes in the presence of B0 and B1 inhomogeneities. NMR Biomed [print-electronic]. 2023 Apr 4/17/2023; e4951. PMID: 37070215, DOI: 10.1002/nbm.4951, ISSN: 1099-1492.
Adelnia F, Davis LT, Acosta LM, Puckett A, Wang F, Zu Z, Harkins KD, Gore JC. R1¿ dispersion in white matter correlates with quantitative metrics of cognitive impairment. Neuroimage Clin [print-electronic]. 2023; 37: 103366. PMID: 36889101, PMCID: PMC10009712, PII: S2213-1582(23)00055-4, DOI: 10.1016/j.nicl.2023.103366, ISSN: 2213-1582.
Wang F, Otsuka T, Adelnia F, Takahashi K, Delgado R, Harkins KD, Zu Z, de Caestecker MP, Harris RC, Gore JC, Takahashi T. Multiparametric magnetic resonance imaging in diagnosis of long-term renal atrophy and fibrosis after ischemia reperfusion induced acute kidney injury in mice. NMR Biomed [print-electronic]. 2022 Oct; 35(10): e4786. PMID: 35704387, DOI: 10.1002/nbm.4786, ISSN: 1099-1492.
Adelnia F, Zu Z, Spear JT, Wang F, Harkins KD, Gore JC. Tissue characterization using R1rho dispersion imaging at low locking fields. Magn Reson Imaging [print-electronic]. 2021 Dec; 84: 1-11. PMID: 34052306, PII: S0730-725X(21)00088-6, DOI: 10.1016/j.mri.2021.05.006, ISSN: 1873-5894.
Reiter DA, Adelnia F, Cameron D, Spencer RG, Ferrucci L. Parsimonious modeling of skeletal muscle perfusion: Connecting the stretched exponential and fractional Fickian diffusion. Magn Reson Med [print-electronic]. 2021 Aug; 86(2): 1045-57. PMID: 33724547, PMCID: PMC8315038, DOI: 10.1002/mrm.28766, ISSN: 1522-2594.
Zampino M, Semba RD, Adelnia F, Spencer RG, Fishbein KW, Schrack JA, Simonsick EM, Ferrucci L. Greater Skeletal Muscle Oxidative Capacity Is Associated With Higher Resting Metabolic Rate: Results From the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci. 2020 Nov 11/13/2020; 75(12): 2262-8. PMID: 32201887, PMCID: PMC7751004, PII: 5810914, DOI: 10.1093/gerona/glaa071, ISSN: 1758-535X.
Adelnia F, Ubaida-Mohien C, Moaddel R, Shardell M, Lyashkov A, Fishbein KW, Aon MA, Spencer RG, Ferrucci L. Proteomic signatures of in vivo muscle oxidative capacity in healthy adults. Aging Cell [print-electronic]. 2020 Apr; 19(4): e13124. PMID: 32196924, PMCID: PMC7189997, DOI: 10.1111/acel.13124, ISSN: 1474-9726.
Adelnia F, Urbanek J, Osawa Y, Shardell M, Brennan NA, Fishbein KW, Spencer RG, Simonsick EM, Schrack JA, Ferrucci L. Moderate-to-Vigorous Physical Activity Is Associated With Higher Muscle Oxidative Capacity in Older Adults. J Am Geriatr Soc [print-electronic]. 2019 Aug; 67(8): 1695-9. PMID: 31116422, PMCID: PMC6684385, DOI: 10.1111/jgs.15991, ISSN: 1532-5415.
Adelnia F, Shardell M, Bergeron CM, Fishbein KW, Spencer RG, Ferrucci L, Reiter DA. Diffusion-weighted MRI with intravoxel incoherent motion modeling for assessment of muscle perfusion in the thigh during post-exercise hyperemia in younger and older adults. NMR Biomed [print-electronic]. 2019 May; 32(5): e4072. PMID: 30861224, PMCID: PMC6530599, DOI: 10.1002/nbm.4072, ISSN: 1099-1492.
Semba RD, Zhang P, Adelnia F, Sun K, Gonzalez-Freire M, Salem N, Brennan N, Spencer RG, Fishbein K, Khadeer M, Shardell M, Moaddel R, Ferrucci L. Low plasma lysophosphatidylcholines are associated with impaired mitochondrial oxidative capacity in adults in the Baltimore Longitudinal Study of Aging. Aging Cell [print-electronic]. 2019 Apr; 18(2): e12915. PMID: 30719830, PMCID: PMC6413748, DOI: 10.1111/acel.12915, ISSN: 1474-9726.
Cameron D, Welch AA, Adelnia F, Bergeron CM, Reiter DA, Dominguez LJ, Brennan NA, Fishbein KW, Spencer RG, Ferrucci L. Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by 31P Magnetic Resonance Spectroscopy, Than With Serum Magnesium. Front Physiol. 2019; 10: 1454. PMID: 31827445, PMCID: PMC6892402, DOI: 10.3389/fphys.2019.01454, ISSN: 1664-042X.
Adelnia F, Cameron D, Bergeron CM, Fishbein KW, Spencer RG, Reiter DA, Ferrucci L. The Role of Muscle Perfusion in the Age-Associated Decline of Mitochondrial Function in Healthy Individuals. Front Physiol. 2019; 10: 427. PMID: 31031645, PMCID: PMC6473080, DOI: 10.3389/fphys.2019.00427, ISSN: 1664-042X.
Gonzalez-Freire M, Adelnia F, Moaddel R, Ferrucci L. Searching for a mitochondrial root to the decline in muscle function with ageing [editorial]. J Cachexia Sarcopenia Muscle [print-electronic]. 2018 Jun; 9(3): 435-40. PMID: 29774990, PMCID: PMC5989834, DOI: 10.1002/jcsm.12313, ISSN: 2190-6009.
Adelnia F, Chiesa A, Bordignon S, Carretta S, Ghirri A, Candini A, Cervetti C, Evangelisti M, Affronte M, Sheikin I, Winpenny R, Timco G, Borsa F, Lascialfari A. Low temperature magnetic properties and spin dynamics in single crystals of Cr8Zn antiferromagnetic molecular rings. J Chem Phys. 2015 Dec 12/28/2015; 143(24): 244321. PMID: 26723685, DOI: 10.1063/1.4938086, ISSN: 1089-7690.
Adelnia F, Bordonali L, Mariani M, Bordignon S, Timco G, Winpenny R, Borsa F, Lascialfari A. Comparison of spin dynamics and magnetic properties in antiferromagnetic closed and open molecular Cr-based rings. J Phys Condens Matter [print-electronic]. 2015 Dec 12/23/2015; 27(50): 506001. PMID: 26609709, DOI: 10.1088/0953-8984/27/50/506001, ISSN: 1361-648X.
Cameron D, Reiter DA, Adelnia F, Ubaida-Mohien C, Bergeron CM, Choi S, Fishbein KW, Spencer RG, Ferrucci L. Age-related changes in human skeletal muscle microstructure and architecture assessed by diffusion-tensor magnetic resonance imaging and their association with muscle strength. Aging Cell [print-electronic]. 2023 Jul; 22(7): e13851. PMID: 37162031, PMCID: PMC10352548, DOI: 10.1111/acel.13851, ISSN: 1474-9726.
Zu Z, Adelnia F, Harkins K, Wang F, Ostenson J, Gore JC. Correction of errors in estimates of T1¿ at low spin-lock amplitudes in the presence of B0 and B1 inhomogeneities. NMR Biomed [print-electronic]. 2023 Apr 4/17/2023; e4951. PMID: 37070215, DOI: 10.1002/nbm.4951, ISSN: 1099-1492.
Adelnia F, Davis LT, Acosta LM, Puckett A, Wang F, Zu Z, Harkins KD, Gore JC. R1¿ dispersion in white matter correlates with quantitative metrics of cognitive impairment. Neuroimage Clin [print-electronic]. 2023; 37: 103366. PMID: 36889101, PMCID: PMC10009712, PII: S2213-1582(23)00055-4, DOI: 10.1016/j.nicl.2023.103366, ISSN: 2213-1582.
Wang F, Otsuka T, Adelnia F, Takahashi K, Delgado R, Harkins KD, Zu Z, de Caestecker MP, Harris RC, Gore JC, Takahashi T. Multiparametric magnetic resonance imaging in diagnosis of long-term renal atrophy and fibrosis after ischemia reperfusion induced acute kidney injury in mice. NMR Biomed [print-electronic]. 2022 Oct; 35(10): e4786. PMID: 35704387, DOI: 10.1002/nbm.4786, ISSN: 1099-1492.
Adelnia F, Zu Z, Spear JT, Wang F, Harkins KD, Gore JC. Tissue characterization using R1rho dispersion imaging at low locking fields. Magn Reson Imaging [print-electronic]. 2021 Dec; 84: 1-11. PMID: 34052306, PII: S0730-725X(21)00088-6, DOI: 10.1016/j.mri.2021.05.006, ISSN: 1873-5894.
Reiter DA, Adelnia F, Cameron D, Spencer RG, Ferrucci L. Parsimonious modeling of skeletal muscle perfusion: Connecting the stretched exponential and fractional Fickian diffusion. Magn Reson Med [print-electronic]. 2021 Aug; 86(2): 1045-57. PMID: 33724547, PMCID: PMC8315038, DOI: 10.1002/mrm.28766, ISSN: 1522-2594.
Zampino M, Semba RD, Adelnia F, Spencer RG, Fishbein KW, Schrack JA, Simonsick EM, Ferrucci L. Greater Skeletal Muscle Oxidative Capacity Is Associated With Higher Resting Metabolic Rate: Results From the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci. 2020 Nov 11/13/2020; 75(12): 2262-8. PMID: 32201887, PMCID: PMC7751004, PII: 5810914, DOI: 10.1093/gerona/glaa071, ISSN: 1758-535X.
Adelnia F, Ubaida-Mohien C, Moaddel R, Shardell M, Lyashkov A, Fishbein KW, Aon MA, Spencer RG, Ferrucci L. Proteomic signatures of in vivo muscle oxidative capacity in healthy adults. Aging Cell [print-electronic]. 2020 Apr; 19(4): e13124. PMID: 32196924, PMCID: PMC7189997, DOI: 10.1111/acel.13124, ISSN: 1474-9726.
Adelnia F, Urbanek J, Osawa Y, Shardell M, Brennan NA, Fishbein KW, Spencer RG, Simonsick EM, Schrack JA, Ferrucci L. Moderate-to-Vigorous Physical Activity Is Associated With Higher Muscle Oxidative Capacity in Older Adults. J Am Geriatr Soc [print-electronic]. 2019 Aug; 67(8): 1695-9. PMID: 31116422, PMCID: PMC6684385, DOI: 10.1111/jgs.15991, ISSN: 1532-5415.
Adelnia F, Shardell M, Bergeron CM, Fishbein KW, Spencer RG, Ferrucci L, Reiter DA. Diffusion-weighted MRI with intravoxel incoherent motion modeling for assessment of muscle perfusion in the thigh during post-exercise hyperemia in younger and older adults. NMR Biomed [print-electronic]. 2019 May; 32(5): e4072. PMID: 30861224, PMCID: PMC6530599, DOI: 10.1002/nbm.4072, ISSN: 1099-1492.
Semba RD, Zhang P, Adelnia F, Sun K, Gonzalez-Freire M, Salem N, Brennan N, Spencer RG, Fishbein K, Khadeer M, Shardell M, Moaddel R, Ferrucci L. Low plasma lysophosphatidylcholines are associated with impaired mitochondrial oxidative capacity in adults in the Baltimore Longitudinal Study of Aging. Aging Cell [print-electronic]. 2019 Apr; 18(2): e12915. PMID: 30719830, PMCID: PMC6413748, DOI: 10.1111/acel.12915, ISSN: 1474-9726.
Cameron D, Welch AA, Adelnia F, Bergeron CM, Reiter DA, Dominguez LJ, Brennan NA, Fishbein KW, Spencer RG, Ferrucci L. Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by 31P Magnetic Resonance Spectroscopy, Than With Serum Magnesium. Front Physiol. 2019; 10: 1454. PMID: 31827445, PMCID: PMC6892402, DOI: 10.3389/fphys.2019.01454, ISSN: 1664-042X.
Adelnia F, Cameron D, Bergeron CM, Fishbein KW, Spencer RG, Reiter DA, Ferrucci L. The Role of Muscle Perfusion in the Age-Associated Decline of Mitochondrial Function in Healthy Individuals. Front Physiol. 2019; 10: 427. PMID: 31031645, PMCID: PMC6473080, DOI: 10.3389/fphys.2019.00427, ISSN: 1664-042X.
Gonzalez-Freire M, Adelnia F, Moaddel R, Ferrucci L. Searching for a mitochondrial root to the decline in muscle function with ageing [editorial]. J Cachexia Sarcopenia Muscle [print-electronic]. 2018 Jun; 9(3): 435-40. PMID: 29774990, PMCID: PMC5989834, DOI: 10.1002/jcsm.12313, ISSN: 2190-6009.
Adelnia F, Chiesa A, Bordignon S, Carretta S, Ghirri A, Candini A, Cervetti C, Evangelisti M, Affronte M, Sheikin I, Winpenny R, Timco G, Borsa F, Lascialfari A. Low temperature magnetic properties and spin dynamics in single crystals of Cr8Zn antiferromagnetic molecular rings. J Chem Phys. 2015 Dec 12/28/2015; 143(24): 244321. PMID: 26723685, DOI: 10.1063/1.4938086, ISSN: 1089-7690.
Adelnia F, Bordonali L, Mariani M, Bordignon S, Timco G, Winpenny R, Borsa F, Lascialfari A. Comparison of spin dynamics and magnetic properties in antiferromagnetic closed and open molecular Cr-based rings. J Phys Condens Matter [print-electronic]. 2015 Dec 12/23/2015; 27(50): 506001. PMID: 26609709, DOI: 10.1088/0953-8984/27/50/506001, ISSN: 1361-648X.