Katherine N. Gibson-Corley, D.V.M., Ph.D.


Faculty Appointments
Professor of Pathology, Microbiology and Immunology
Ph.D., Iowa State University, Ames, IowaD.V.M., Iowa State University, Ames, IowaB.A., Biology and Molecualar Biology, Saint Olaf College, Northfield, Minnesota
Office Address
AA-6206 MCN
1161 21st Ave South
Nashville, TN 27232
Research Description
Dr. Katherine Gibson-Corley is a Veterinary Pathologist, collaborative researcher and specialist in comparative pathology and animal modeling of human diseases. She has expertise across a board range of research topics including cancer biology, pre-eclampsia, Cystic Fibrosis, inherited retinal diseases, allergic lung disease and infectious diseases such as Leishmaniasis. Dr. Gibson-Corley is also the Director of Comparative Pathology and Research Histology in the Translational Pathology Shared Resource (TPSR) which is a Core Laboratory devoted to pathology and histology services for researchers. Her goal is to collaboratively advance biomedical research as an integrated comparative pathologist and mentor students and faculty on how to use a comparative pathologist to further their studies.
Research Keywords
Veterinary Pathology, Comparative Pathology, Animal Models, Mouse Models, Neuropathology, Ocular pathology, Genetically-Engineered Mice
Eddie AM, Chen KW, Schenkel LB, Swinger KK, Molina JR, Kunii K, Raybuck AL, Keilhack H, Gibson-Corley KN, Niepel M, Peebles RS, Boothby MR, Cho SH. Selective Pharmaceutical Inhibition of PARP14 Mitigates Allergen-Induced IgE and Mucus Overproduction in a Mouse Model of Pulmonary Allergic Response. Immunohorizons. 2022 Jul 7/11/2022; 6(7): 432-46. PMID: 35817532, PII: immunohorizons.2100107, DOI: 10.4049/immunohorizons.2100107, ISSN: 2573-7732.

Kinney KJ, Tang SS, Wu XJ, Tran PM, Bharadwaj NS, Gibson-Corley KN, Forsythe AN, Kulhankova K, Gumperz JE, Salgado-Pabón W. SEC is an antiangiogenic virulence factor that promotes Staphylococcus aureus endocarditis independent of superantigen activity. Sci Adv [print-electronic]. 2022 May 5/13/2022; 8(19): eabo1072. PMID: 35544579, PMCID: PMC9094652, DOI: 10.1126/sciadv.abo1072, ISSN: 2375-2548.

Snyder JM, Radaelli E, Goeken A, Businga T, Boyden AW, Karandikar NJ, Gibson-Corley KN. Perfusion with 10% neutral-buffered formalin is equivalent to 4% paraformaldehyde for histopathology and immunohistochemistry in a mouse model of experimental autoimmune encephalomyelitis. Vet Pathol [print-electronic]. 2022 May; 59(3): 498-505. PMID: 35130806, PMCID: PMC9364762, DOI: 10.1177/03009858221075588, ISSN: 1544-2217.

Tucker BA, Burnight ER, Cranston CM, Ulferts MJ, Luse MA, Westfall T, Scott CA, Marsden A, Gibson-Corley K, Wiley LA, Han IC, Slusarski DC, Mullins RF, Stone EM. Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa. Gene Ther [print-electronic]. 2022 May; 29(5): 259-88. PMID: 34518651, PMCID: PMC9159943, PII: 10.1038/s41434-021-00291-5, DOI: 10.1038/s41434-021-00291-5, ISSN: 1476-5462.

Khan IN, Gibson-Corley KN, Coppock JD, Simons AL. Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs. Head Neck Pathol [print-electronic]. 2022 Mar 3/25/2022; PMID: 35334093, PII: 10.1007/s12105-022-01440-x, DOI: 10.1007/s12105-022-01440-x, ISSN: 1936-0568.

He N, Liu X, Vegter AR, Evans TIA, Gray JS, Guo J, Moll SR, Guo LJ, Luo M, Ma N, Sun X, Liang B, Yan Z, Feng Z, Qi L, Joshi AS, Shahin W, Yi Y, Gibson-Corley KN, Hoffman EA, Wang K, Mueller C, Engelhardt JF, Rosen BH. Ferret models of alpha-1 antitrypsin deficiency develop lung and liver disease. JCI Insight. 2022 Mar 3/8/2022; 7(5): PMID: 35104244, PMCID: PMC8983124, PII: 143004, DOI: 10.1172/jci.insight.143004, ISSN: 2379-3708.

Eti NA, Flor S, Iqbal K, Scott RL, Klenov VE, Gibson-Corley KN, Soares MJ, Ludewig G, Robertson LW. PCB126 induced toxic actions on liver energy metabolism is mediated by AhR in rats. Toxicology [print-electronic]. 2022 Jan 1/30/2022; 466: 153054. PMID: 34848246, PMCID: PMC8748418, PII: S0300-483X(21)00376-0, DOI: 10.1016/j.tox.2021.153054, ISSN: 1879-3185.

Wongpattaraworakul W, Gibson-Corley KN, Choi A, Buchakjian MR, Lanzel EA, Rajan Kd A, Simons AL. Prognostic Role of Combined EGFR and Tumor-Infiltrating Lymphocytes in Oral Squamous Cell Carcinoma. Front Oncol. 2022; 12: 885236. PMID: 35957892, PMCID: PMC9357911, DOI: 10.3389/fonc.2022.885236, ISSN: 2234-943X.

Han IC, Bohrer LR, Gibson-Corley KN, Wiley LA, Shrestha A, Harman BE, Jiao C, Sohn EH, Wendland R, Allen BN, Worthington KS, Mullins RF, Stone EM, Tucker BA. Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats. Cell Transplant. 2022 Jan; 31: 9636897221104451. PMID: 35758274, PMCID: PMC9247396, DOI: 10.1177/09636897221104451, ISSN: 1555-3892.

Evans LP, Gibson-Corley KN, Mullins RF, Tucker BA, Trent A, Stone EM, Jones KA. An Unusual Presentation of CLN3-Associated Batten Disease With Classic Histopathologic and Ultrastructural Findings. J Neuropathol Exp Neurol [print-electronic]. 2021 Nov 11/19/2021; 80(11): 1081–1084. PMID: 34313756, PMCID: PMC8921633, PII: 6329083, DOI: 10.1093/jnen/nlab064, ISSN: 1554-6578.

Scorza BM, Mahachi KG, Cox AC, Toepp AJ, Leal-Lima A, Kumar Kushwaha A, Kelly P, Meneses C, Wilson G, Gibson-Corley KN, Bartholomay L, Kamhawi S, Petersen CA. Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism. PLoS Negl Trop Dis. 2021 Oct; 15(10): e0009366. PMID: 34613967, PMCID: PMC8523039, PII: PNTD-D-21-00476, DOI: 10.1371/journal.pntd.0009366, ISSN: 1935-2735.

Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, Lu J, Lu J, Huang X, Xiang H, Cheng J, Wang D, Wang Z, Tang J, Hu J, Wang Z, Liu H, Li M, Zhuang H, Avram D, Zhou D, Bacher R, Zheng SG, Wu X, Zakharia Y, Zhang W. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021 Oct 10/1/2021; 12(1): 5764. PMID: 34599187, PMCID: PMC8486774, PII: 10.1038/s41467-021-26091-4, DOI: 10.1038/s41467-021-26091-4, ISSN: 2041-1723.

Webster JD, Solon M, Gibson-Corley KN. Validating Immunohistochemistry Assay Specificity in Investigative Studies: Considerations for a Weight of Evidence Approach. Vet Pathol [print-electronic]. 2021 Sep; 58(5): 829-40. PMID: 32975488, DOI: 10.1177/0300985820960132, ISSN: 1544-2217.

Yi Y, Sun X, Liang B, He N, Gibson-Corley KN, Norris AW, Engelhardt JF, Uc A. Acute pancreatitis-induced islet dysfunction in ferrets. Pancreatology [print-electronic]. 2021 Aug; 21(5): 839-47. PMID: 33994067, PMCID: PMC8355067, PII: S1424-3903(21)00147-2, DOI: 10.1016/j.pan.2021.04.008, ISSN: 1424-3911.

Jensen SN, Cady NM, Shahi SK, Peterson SR, Gupta A, Gibson-Corley KN, Mangalam AK. Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis. Sci Adv [electronic-print]. 2021 Jul; 7(28): PMID: 34244137, PMCID: PMC8270496, PII: 7/28/eabd4595, DOI: 10.1126/sciadv.abd4595, ISSN: 2375-2548.

Gibson-Corley KN, Engelhardt JF. Animal Models and Their Role in Understanding the Pathophysiology of Cystic Fibrosis-Associated Gastrointestinal Lesions. Annu Rev Pathol. 2021 Jan 1/24/2021; 16: 51-67. PMID: 33497264, DOI: 10.1146/annurev-pathol-022420-105133, ISSN: 1553-4014.

Cheng Y, Borcherding N, Ogunsakin A, Lemke-Miltner CD, Gibson-Corley KN, Rajan A, Choi AB, Wongpattaraworakul W, Chan CHF, Salem AK, Weiner GJ, Simons AL. The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent. Sci Rep. 2021 Jan 1/15/2021; 11(1): 1535. PMID: 33452311, PMCID: PMC7810827, PII: 10.1038/s41598-020-80957-z, DOI: 10.1038/s41598-020-80957-z, ISSN: 2045-2322.

Jensen IJ, Jensen SN, Sjaastad FV, Gibson-Corley KN, Dileepan T, Griffith TS, Mangalam AK, Badovinac VP. Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells. Elife. 2020 Nov 11/16/2020; 9: PMID: 33191915, PMCID: PMC7721438, PII: 55800, DOI: 10.7554/eLife.55800, ISSN: 2050-084X.

Hamity MV, White SR, Blum C, Gibson-Corley KN, Hammond DL. Nicotinamide riboside relieves paclitaxel-induced peripheral neuropathy and enhances suppression of tumor growth in tumor-bearing rats. Pain. 2020 Oct; 161(10): 2364-75. PMID: 32433266, PMCID: PMC7508763, PII: 00006396-202010000-00017, DOI: 10.1097/j.pain.0000000000001924, ISSN: 1872-6623.

Sapouckey SA, Morselli LL, Deng G, Patil CN, Balapattabi K, Oliveira V, Claflin KE, Gomez J, Pearson NA, Potthoff MJ, Gibson-Corley KN, Sigmund CD, Grobe JL. Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or agouti-related peptide. Am J Physiol Regul Integr Comp Physiol [print-electronic]. 2020 May 5/1/2020; 318(5): R855-R869. PMID: 32186897, PMCID: PMC7272763, DOI: 10.1152/ajpregu.00297.2019, ISSN: 1522-1490.

Holland MT, Seaman SC, Woodroffe RW, Fredericks DC, Kovach CK, Gibson-Corley KN, Gillies GT, Howard MA. In Vivo Testing of a Prototype Intradural Spinal Cord Stimulator in a Porcine Model. World Neurosurg [print-electronic]. 2020 May; 137: e634-e641. PMID: 32112934, PII: S1878-8750(20)30375-2, DOI: 10.1016/j.wneu.2020.02.100, ISSN: 1878-8769.

Kluz PN, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, Kim MC, Wang L, Zhang Y, Li W, Stipp C, Gibson-Corley KN, Zhao C, Qi HH, Bellizzi A, Tao AW, Sugg S, Weigel RJ, Zhou D, Shen X, Zhang W. Cancer cell-intrinsic function of CD177 in attenuating ß-catenin signaling. Oncogene [print-electronic]. 2020 Apr; 39(14): 2877-89. PMID: 32042113, PMCID: PMC7127950, PII: 10.1038/s41388-020-1203-x, DOI: 10.1038/s41388-020-1203-x, ISSN: 1476-5594.

Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Hypertension [print-electronic]. 2020 Feb; 75(2): 569-79. PMID: 31865781, PMCID: PMC7027931, DOI: 10.1161/HYPERTENSIONAHA.119.14056, ISSN: 1524-4563.

Shahi SK, Jensen SN, Murra AC, Tang N, Guo H, Gibson-Corley KN, Zhang J, Karandikar NJ, Murray JA, Mangalam AK. Human Commensal Prevotella histicola Ameliorates Disease as Effectively as Interferon-Beta in the Experimental Autoimmune Encephalomyelitis. Front Immunol. 2020; 11: 578648. PMID: 33362764, PMCID: PMC7759500, DOI: 10.3389/fimmu.2020.578648, ISSN: 1664-3224.

Li M, Liu D, Lee D, Kapoor S, Gibson-Corley KN, Quinn TP, Sagastume EA, Mott SL, Walsh SA, Acevedo MR, Johnson FL, Schultz MK. Enhancing the Efficacy of Melanocortin 1 Receptor-Targeted Radiotherapy by Pharmacologically Upregulating the Receptor in Metastatic Melanoma. Mol Pharm [print-electronic]. 2019 Sep 9/3/2019; 16(9): 3904-15. PMID: 31318566, PMCID: PMC6765223, DOI: 10.1021/acs.molpharmaceut.9b00512, ISSN: 1543-8392.

Sun X, Yi Y, Liang B, Yang Y, He N, Ode KL, Uc A, Wang K, Gibson-Corley KN, Engelhardt JF, Norris AW. Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin. J Cyst Fibros [print-electronic]. 2019 Jul; 18(4): 557-65. PMID: 30738804, PMCID: PMC6591024, PII: S1569-1993(19)30016-5, DOI: 10.1016/j.jcf.2019.01.010, ISSN: 1873-5010.

Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis. Sci Transl Med. 2019 Mar 3/27/2019; 11(485): PMID: 30918114, PMCID: PMC6489481, PII: 11/485/eaau7531, DOI: 10.1126/scitranslmed.aau7531, ISSN: 1946-6242.

Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K, McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D, Narasimhan B, Simons AL. Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma. J Immunother Cancer. 2019 Mar 3/19/2019; 7(1): 79. PMID: 30890189, PMCID: PMC6425573, PII: 10.1186/s40425-019-0550-z, DOI: 10.1186/s40425-019-0550-z, ISSN: 2051-1426.

Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Oncogene [print-electronic]. 2019 Mar; 38(13): 2351-63. PMID: 30518876, PMCID: PMC6440811, PII: 10.1038/s41388-018-0592-6, DOI: 10.1038/s41388-018-0592-6, ISSN: 1476-5594.

Espinosa-Cotton M, Fertig EJ, Stabile LP, Gaither-Davis A, Bauman JE, Schmitz S, Gibson-Corley KN, Cheng Y, Jensen IJ, Badovinac VP, Laux D, Simons AL. A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. Biomark Res. 2019; 7: 14. PMID: 31346466, PMCID: PMC6636109, PII: 164, DOI: 10.1186/s40364-019-0164-0, ISSN: 2050-7771.

Rajan A, Gibson-Corley KN, Choi AB, Ofori-Amanfo GK, Ten Eyck P, Espinosa-Cotton M, Sperry SM, Simons AL. Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. J Oncol. 2019; 2019: 5859680. PMID: 31320902, PMCID: PMC6607721, DOI: 10.1155/2019/5859680, ISSN: 1687-8450.

Shahi SK, Freedman SN, Murra AC, Zarei K, Sompallae R, Gibson-Corley KN, Karandikar NJ, Murray JA, Mangalam AK. Prevotella histicola, A Human Gut Commensal, Is as Potent as COPAXONE® in an Animal Model of Multiple Sclerosis. Front Immunol. 2019; 10: 462. PMID: 30984162, PMCID: PMC6448018, DOI: 10.3389/fimmu.2019.00462, ISSN: 1664-3224.

Alexander MS, Wilkes JG, Schroeder SR, Buettner GR, Wagner BA, Du J, Gibson-Corley K, O'Leary BR, Spitz DR, Buatti JM, Berg DJ, Bodeker KL, Vollstedt S, Brown HA, Allen BG, Cullen JJ. Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer. Cancer Res [print-electronic]. 2018 Dec 12/15/2018; 78(24): 6838-51. PMID: 30254147, PMCID: PMC6295907, PII: 0008-5472.CAN-18-1680, DOI: 10.1158/0008-5472.CAN-18-1680, ISSN: 1538-7445.

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Uchida K, Ward JM, Webster JD, Yamate J. Observational Study Design in Veterinary Pathology, Part 2: Methodology. Vet Pathol [print-electronic]. 2018 Nov; 55(6): 774-85. PMID: 30227783, DOI: 10.1177/0300985818798121, ISSN: 1544-2217.

Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. JCI Insight. 2018 Oct 10/4/2018; 3(19): PMID: 30282823, PMCID: PMC6237463, PII: 99403, DOI: 10.1172/jci.insight.99403, ISSN: 2379-3708.

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Uchida K, Ward JM, Webster JD, Yamate J. Observational Study Design in Veterinary Pathology, Part 1: Study Design. Vet Pathol [print-electronic]. 2018 Sep; 55(5): 607-21. PMID: 30071806, DOI: 10.1177/0300985818785705, ISSN: 1544-2217.

Perschbacher KJ, Deng G, Fisher RA, Gibson-Corley KN, Santillan MK, Grobe JL. Regulators of G protein signaling in cardiovascular function during pregnancy. Physiol Genomics [print-electronic]. 2018 Aug 8/1/2018; 50(8): 590-604. PMID: 29702036, PMCID: PMC6139632, DOI: 10.1152/physiolgenomics.00037.2018, ISSN: 1531-2267.

Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW. PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver. Toxicol Sci. 2018 Jun 6/1/2018; 163(2): 440-53. PMID: 29474705, PMCID: PMC5974782, PII: 4883307, DOI: 10.1093/toxsci/kfy041, ISSN: 1096-0929.

Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB. Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs. Lab Invest [print-electronic]. 2018 Jun; 98(6): 825-38. PMID: 29467455, PMCID: PMC6019641, PII: 10.1038/s41374-018-0026-7, DOI: 10.1038/s41374-018-0026-7, ISSN: 1530-0307.

Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL. Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin. Am J Physiol Regul Integr Comp Physiol [print-electronic]. 2018 Jun 6/1/2018; 314(6): R770-R780. PMID: 29364700, PMCID: PMC6032302, DOI: 10.1152/ajpregu.00435.2017, ISSN: 1522-1490.

Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF. Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets. Am J Respir Crit Care Med. 2018 May 5/15/2018; 197(10): 1308-18. PMID: 29327941, PMCID: PMC5955060, DOI: 10.1164/rccm.201708-1616OC, ISSN: 1535-4970.

Fricke EM, Elgin TG, Gong H, Reese J, Gibson-Corley KN, Weiss RM, Zimmerman K, Bowdler NC, Kalantera KM, Mills DA, Underwood MA, McElroy SJ. Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood. Am J Reprod Immunol [print-electronic]. 2018 May; 79(5): e12816. PMID: 29369434, PMCID: PMC5908742, DOI: 10.1111/aji.12816, ISSN: 1600-0897.

Gibbins KJ, Gibson-Corley KN, Brown AS, Wieben M, Law RC, Fung CM. Effects of excess thromboxane A2 on placental development and nutrient transporters in a Mus musculus model of fetal growth restriction. Biol Reprod. 2018 May 5/1/2018; 98(5): 695-704. PMID: 29351577, PMCID: PMC6248656, PII: 4813325, DOI: 10.1093/biolre/ioy006, ISSN: 1529-7268.

Rotti PG, Xie W, Poudel A, Yi Y, Sun X, Tyler SR, Uc A, Norris AW, Hara M, Engelhardt JF, Gibson-Corley KN. Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets. Am J Pathol [print-electronic]. 2018 Apr; 188(4): 876-90. PMID: 29366680, PMCID: PMC5963477, PII: S0002-9440(17)30728-9, DOI: 10.1016/j.ajpath.2017.12.015, ISSN: 1525-2191.

Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK. Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia. Clin Sci (Lond) [electronic-print]. 2018 Feb 2/14/2018; 132(3): 419-36. PMID: 29371289, PMCID: PMC5947858, PII: CS20171059, DOI: 10.1042/CS20171059, ISSN: 1470-8736.

Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ. Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1a (HIF-1a) in pancreatic adenocarcinoma. Clin Exp Metastasis [print-electronic]. 2018 Feb; 35(1-2): 37-51. PMID: 29396728, PMCID: PMC5959274, PII: 10.1007/s10585-018-9876-z, DOI: 10.1007/s10585-018-9876-z, ISSN: 1573-7276.

Hornick EE, Banoth B, Miller AM, Zacharias ZR, Jain N, Wilson ME, Gibson-Corley KN, Legge KL, Bishop GA, Sutterwala FS, Cassel SL. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection. J Immunol [print-electronic]. 2018 Feb 2/1/2018; 200(3): 1188-97. PMID: 29282312, PMCID: PMC5831365, PII: jimmunol.1700999, DOI: 10.4049/jimmunol.1700999, ISSN: 1550-6606.

Grinnage-Pulley TL, Kabotso DEK, Rintelmann CL, Roychoudhury R, Schaut RG, Toepp AJ, Gibson-Corley KN, Parrish M, Pohl NLB, Petersen CA. Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions. Infect Immun [electronic-print]. 2018 Jan; 86(1): PMID: 29061708, PMCID: PMC5736800, PII: IAI.00672-17, DOI: 10.1128/IAI.00672-17, ISSN: 1098-5522.

Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity. Mol Metab [print-electronic]. 2017 Nov; 6(11): 1468-79. PMID: 29107293, PMCID: PMC5681281, PII: S2212-8778(17)30682-8, DOI: 10.1016/j.molmet.2017.09.002, ISSN: 2212-8778.

Mangalam A, Shahi SK, Luckey D, Karau M, Marietta E, Luo N, Choung RS, Ju J, Sompallae R, Gibson-Corley K, Patel R, Rodriguez M, David C, Taneja V, Murray J. Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease. Cell Rep. 2017 Aug 8/8/2017; 20(6): 1269-77. PMID: 28793252, PMCID: PMC5763484, PII: S2211-1247(17)30997-X, DOI: 10.1016/j.celrep.2017.07.031, ISSN: 2211-1247.

Itani FR, Sinha S, Brate AA, Pewe LL, Gibson-Corley KN, Harty JT, Karandikar NJ. Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen. Sci Rep. 2017 May 5/8/2017; 7(1): 1519. PMID: 28484224, PMCID: PMC5431563, PII: 10.1038/s41598-017-01771-8, DOI: 10.1038/s41598-017-01771-8, ISSN: 2045-2322.

Wilson S, Abode-Iyamah KO, Miller JW, Reddy CG, Safayi S, Fredericks DC, Jeffery ND, DeVries-Watson NA, Shivapour SK, Viljoen S, Dalm BD, Gibson-Corley KN, Johnson MD, Gillies GT, Howard MA. An ovine model of spinal cord injury. J Spinal Cord Med [print-electronic]. 2017 May; 40(3): 346-60. PMID: 27759502, PMCID: PMC5472023, DOI: 10.1080/10790268.2016.1222475, ISSN: 2045-7723.

Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL. Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. J Clin Invest [print-electronic]. 2017 Apr 4/3/2017; 127(4): 1414-24. PMID: 28263184, PMCID: PMC5373887, PII: 88641, DOI: 10.1172/JCI88641, ISSN: 1558-8238.

Xiu Y, Xue WY, Lambertz A, Leidinger M, Gibson-Corley K, Zhao C. Constitutive Activation of NIK Impairs the Self-Renewal of Hematopoietic Stem/Progenitor Cells and Induces Bone Marrow Failure. Stem Cells [print-electronic]. 2017 Mar; 35(3): 777-86. PMID: 27733012, PMCID: PMC5817891, DOI: 10.1002/stem.2523, ISSN: 1549-4918.

Varzavand A, Hacker W, Ma D, Gibson-Corley K, Hawayek M, Tayh OJ, Brown JA, Henry MD, Stipp CS. A3ß1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway. Cancer Res [print-electronic]. 2016 Nov 11/15/2016; 76(22): 6577-87. PMID: 27680681, PMCID: PMC5290210, PII: 0008-5472.CAN-16-1483, DOI: 10.1158/0008-5472.CAN-16-1483, ISSN: 1538-7445.

Stanam A, Gibson-Corley KN, Love-Homan L, Ihejirika N, Simons AL. Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma. Oncotarget. 2016 Nov 11/15/2016; 7(46): 76087-100. PMID: 27738319, PMCID: PMC5342798, PII: 12590, DOI: 10.18632/oncotarget.12590, ISSN: 1949-2553.

Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. Assessment of the Mitigative Capacity of Dietary Zinc on PCB126 Hepatotoxicity and the Contribution of Zinc to Toxicity. Chem Res Toxicol [print-electronic]. 2016 May 5/16/2016; 29(5): 851-9. PMID: 26967026, PMCID: PMC5100827, DOI: 10.1021/acs.chemrestox.6b00022, ISSN: 1520-5010.

Yi Y, Sun X, Gibson-Corley K, Xie W, Liang B, He N, Tyler SR, Uc A, Philipson LH, Wang K, Hara M, Ode KL, Norris AW, Engelhardt JF. A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology [print-electronic]. 2016 May; 157(5): 1852-65. PMID: 26862997, PMCID: PMC4870869, DOI: 10.1210/en.2015-1935, ISSN: 1945-7170.

Zhang L, Blackwell K, Workman LM, Gibson-Corley KN, Olivier AK, Bishop GA, Habelhah H. TRAF2 exerts opposing effects on basal and TNFa-induced activation of the classic IKK complex in hematopoietic cells in mice. J Cell Sci [print-electronic]. 2016 Apr 4/1/2016; 129(7): 1455-67. PMID: 26872784, PMCID: PMC4852721, PII: jcs.180554, DOI: 10.1242/jcs.180554, ISSN: 1477-9137.

Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. J Infect Dis [print-electronic]. 2016 Mar 3/1/2016; 213(5): 712-22. PMID: 26486634, PMCID: PMC4747621, PII: jiv499, DOI: 10.1093/infdis/jiv499, ISSN: 1537-6613.

Fredericks D, Petersen EB, Watson N, Grosland N, Gibson-Corley K, Smucker J. Comparison of Two Synthetic Bone Graft Products in a Rabbit Posterolateral Fusion Model. Iowa Orthop J. 2016; 36: 167-73. PMID: 27528855, PMCID: PMC4910791, ISSN: 1555-1377.

Gibson-Corley KN, Boyden AW, Leidinger MR, Lambertz AM, Ofori-Amanfo G, Naumann PW, Goeken JA, Karandikar NJ. A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis. PeerJ. 2016; 4: e1600. PMID: 26855861, PMCID: PMC4741089, PII: 1600, DOI: 10.7717/peerj.1600, ISSN: 2167-8359.

Klaren WD, Flor S, Gibson-Corley KN, Ludewig G, Robertson LW. Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption. Toxicol Rep. 2016; 3: 21-8. PMID: 26770886, PMCID: PMC4710377, DOI: 10.1016/j.toxrep.2015.12.001, ISSN: 2214-7500.

Gibson-Corley KN, Meyerholz DK, Engelhardt JF. Pancreatic pathophysiology in cystic fibrosis. J Pathol [print-electronic]. 2016 Jan; 238(2): 311-20. PMID: 26365583, PMCID: PMC4699289, DOI: 10.1002/path.4634, ISSN: 1096-9896.

Sandgren JA, Scroggins SM, Santillan DA, Devor EJ, Gibson-Corley KN, Pierce GL, Sigmund CD, Santillan MK, Grobe JL. Vasopressin: the missing link for preeclampsia?. Am J Physiol Regul Integr Comp Physiol [print-electronic]. 2015 Nov 11/1/2015; 309(9): R1062-4. PMID: 25810383, PMCID: PMC4666952, PII: ajpregu.00073.2015, DOI: 10.1152/ajpregu.00073.2015, ISSN: 1522-1490.

Adamcakova-Dodd A, Monick MM, Powers LS, Gibson-Corley KN, Thorne PS. Effects of prenatal inhalation exposure to copper nanoparticles on murine dams and offspring. Part Fibre Toxicol. 2015 Oct 10/6/2015; 12: 30. PMID: 26437892, PMCID: PMC4594905, PII: 10.1186/s12989-015-0105-5, DOI: 10.1186/s12989-015-0105-5, ISSN: 1743-8977.

Hu X, Adamcakova-Dodd A, Lehmler HJ, Gibson-Corley K, Thorne PS. Toxicity Evaluation of Exposure to an Atmospheric Mixture of Polychlorinated Biphenyls by Nose-Only and Whole-Body Inhalation Regimens. Environ Sci Technol [print-electronic]. 2015 Oct 10/6/2015; 49(19): 11875-83. PMID: 26348937, PMCID: PMC4711378, DOI: 10.1021/acs.est.5b02865, ISSN: 1520-5851.

Olivier AK, Gibson-Corley KN, Meyerholz DK. Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology. Am J Physiol Gastrointest Liver Physiol [print-electronic]. 2015 Mar 3/15/2015; 308(6): G459-71. PMID: 25591863, PMCID: PMC4360044, PII: ajpgi.00146.2014, DOI: 10.1152/ajpgi.00146.2014, ISSN: 1522-1547.

Wen JH, Wen H, Gibson-Corley KN, Glenn KA. FBG1 Is the Final Arbitrator of A1AT-Z Degradation. PLoS One. 2015; 10(8): e0135591. PMID: 26295339, PMCID: PMC4546667, PII: PONE-D-14-32911, DOI: 10.1371/journal.pone.0135591, ISSN: 1932-6203.

Santillan MK, Pelham CJ, Ketsawatsomkron P, Santillan DA, Davis DR, Devor EJ, Gibson-Corley KN, Scroggins SM, Grobe JL, Yang B, Hunter SK, Sigmund CD. Pregnant mice lacking indoleamine 2,3-dioxygenase exhibit preeclampsia phenotypes. Physiol Rep [electronic-print]. 2015 Jan 1/1/2015; 3(1): PMID: 25602015, PMCID: PMC4387753, PII: 3/1/e12257, DOI: 10.14814/phy2.12257, ISSN: 2051-817X.

Santillan MK, Santillan DA, Scroggins SM, Min JY, Sandgren JA, Pearson NA, Leslie KK, Hunter SK, Zamba GK, Gibson-Corley KN, Grobe JL. Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse model. Hypertension [print-electronic]. 2014 Oct; 64(4): 852-9. PMID: 25001273, PMCID: PMC4162750, PII: HYPERTENSIONAHA.114.03848, DOI: 10.1161/HYPERTENSIONAHA.114.03848, ISSN: 1524-4563.

Joshi VB, Adamcakova-Dodd A, Jing X, Wongrakpanich A, Gibson-Corley KN, Thorne PS, Salem AK. Development of a poly (lactic-co-glycolic acid) particle vaccine to protect against house dust mite induced allergy. AAPS J [print-electronic]. 2014 Sep; 16(5): 975-85. PMID: 24981892, PMCID: PMC4147059, DOI: 10.1208/s12248-014-9624-5, ISSN: 1550-7416.

Gibson-Corley KN, Rogers LM, Goeken A, Dupuy AJ, Meyerholz DK. Keratoacanthoma Pathobiology in Mouse Models. Diseases. 2014 May 5/23/2014; 2(2): 106-19. PMID: 25309748, PMCID: PMC4190131, DOI: 10.3390/diseases2020106, ISSN: 2079-9721.

Gibson-Corley KN, Bockenstedt MM, Li H, Boggiatto PM, Phanse Y, Petersen CA, Bellaire BH, Jones DE. An in vitro model of antibody-enhanced killing of the intracellular parasite Leishmania amazonensis. PLoS One. 2014; 9(9): e106426. PMID: 25191842, PMCID: PMC4156363, PII: PONE-D-14-24985, DOI: 10.1371/journal.pone.0106426, ISSN: 1932-6203.

Gibson-Corley KN, Flouty O, Oya H, Gillies GT, Howard MA. Postsurgical pathologies associated with intradural electrical stimulation in the central nervous system: design implications for a new clinical device. Biomed Res Int [print-electronic]. 2014; 2014: 989175. PMID: 24800260, PMCID: PMC3988712, DOI: 10.1155/2014/989175, ISSN: 2314-6141.

Zhou B, Gibson-Corley KN, Herndon ME, Sun Y, Gustafson-Wagner E, Teoh-Fitzgerald M, Domann FE, Henry MD, Stipp CS. Integrin a3ß1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma. Mol Cancer Res [print-electronic]. 2014 Jan; 12(1): 143-54. PMID: 24002891, PMCID: PMC3947021, DOI: 10.1158/1541-7786.MCR-13-0184, ISSN: 1557-3125.

Hochstedler CM, Leidinger MR, Maher-Sturm MT, Gibson-Corley KN, Meyerholz DK. Immunohistochemical detection of arginase-I expression in formalin-fixed lung and other tissues. J Histotechnol. 2013 Dec; 36(4): 128-34. PMID: 25332513, PMCID: PMC4201120, DOI: 10.1179/2046023613Y.0000000032, ISSN: 0147-8885.

Gregory NS, Gibson-Corley K, Frey-Law L, Sluka KA. Fatigue-enhanced hyperalgesia in response to muscle insult: induction and development occur in a sex-dependent manner. Pain [print-electronic]. 2013 Dec; 154(12): 2668-76. PMID: 23906552, PMCID: PMC3957416, PII: 00006396-201312000-00015, DOI: 10.1016/j.pain.2013.07.047, ISSN: 1872-6623.

Gibson-Corley KN, Olivier AK, Meyerholz DK. Principles for valid histopathologic scoring in research. Vet Pathol [print-electronic]. 2013 Nov; 50(6): 1007-15. PMID: 23558974, PMCID: PMC3795863, PII: 0300985813485099, DOI: 10.1177/0300985813485099, ISSN: 1544-2217.

Whittier KL, Boese EA, Gibson-Corley KN, Kirby PA, Darbro BW, Qian Q, Ingram WJ, Robertson T, Remke M, Taylor MD, O'Dorisio MS. G-protein coupled receptor expression patterns delineate medulloblastoma subgroups. Acta Neuropathol Commun. 2013 Oct 10/10/2013; 1: 66. PMID: 24252460, PMCID: PMC3893540, PII: 2051-5960-1-66, DOI: 10.1186/2051-5960-1-66, ISSN: 2051-5960.

Simons AL, Lu P, Gibson-Corley KN, Robinson RA, Meyerholz DK, Colgan JD. The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation. Lab Invest [print-electronic]. 2013 Jun; 93(6): 711-9. PMID: 23608756, PMCID: PMC3669254, PII: labinvest201362, DOI: 10.1038/labinvest.2013.62, ISSN: 1530-0307.

Flouty OE, Oya H, Kawasaki H, Reddy CG, Fredericks DC, Gibson-Corley KN, Jeffery ND, Gillies GT, Howard MA. Intracranial somatosensory responses with direct spinal cord stimulation in anesthetized sheep. PLoS One [print-electronic]. 2013; 8(2): e56266. PMID: 23457542, PMCID: PMC3574132, PII: PONE-D-12-34427, DOI: 10.1371/journal.pone.0056266, ISSN: 1932-6203.

Gibson-Corley KN, Oya H, Flouty O, Fredericks DC, Jeffery ND, Gillies GT, Howard MA. Ovine tests of a novel spinal cord neuromodulator and dentate ligament fixation method. J Invest Surg. 2012 Dec; 25(6): 366-74. PMID: 23215793, DOI: 10.3109/08941939.2012.677967, ISSN: 1521-0553.

Flouty O, Oya H, Kawasaki H, Wilson S, Reddy CG, Jeffery ND, Brennan TJ, Gibson-Corley KN, Utz M, Gillies GT, Howard MA. A new device concept for directly modulating spinal cord pathways: initial in vivo experimental results. Physiol Meas [print-electronic]. 2012 Dec; 33(12): 2003-15. PMID: 23151433, DOI: 10.1088/0967-3334/33/12/2003, ISSN: 1361-6579.

Olivier AK, Naumann P, Goeken A, Hochstedler C, Sturm M, Rodgers JR, Gibson-Corley KN, Meyerholz DK. Genetically modified species in research: Opportunities and challenges for the histology core laboratory. J Histotechnol. 2012 Jul 7/1/2012; 35(2): 63-7. PMID: 22904582, PMCID: PMC3419433, DOI: 10.1179/2046023612y.0000000003, ISSN: 0147-8885.

Gibson-Corley KN, Boggiatto PM, Bockenstedt MM, Petersen CA, Waldschmidt TJ, Jones DE. Promotion of a functional B cell germinal center response after Leishmania species co-infection is associated with lesion resolution. Am J Pathol [print-electronic]. 2012 May; 180(5): 2009-17. PMID: 22429963, PMCID: PMC3349825, PII: S0002-9440(12)00146-0, DOI: 10.1016/j.ajpath.2012.01.012, ISSN: 1525-2191.

Gibson-Corley KN, Hochstedler C, Sturm M, Rogers J, Olivier AK, Meyerholz DK. Successful Integration of the Histology Core Laboratory in Translational Research. J Histotechnol. 2012 Apr 4/1/2012; 35(1): 17-21. PMID: 22904581, PMCID: PMC3419435, DOI: 10.1179/2046023612Y.0000000001, ISSN: 0147-8885.

Gibson-Corley KN, Haynes JS. Disseminated T-cell lymphoma in a bonobo (Pan paniscus). J Vet Diagn Invest [print-electronic]. 2012 Jan; 24(1): 238-40. PMID: 22362962, PII: 1040638711427175, DOI: 10.1177/1040638711427175, ISSN: 1943-4936.

Boggiatto PM, Gibson-Corley KN, Metz K, Gallup JM, Hostetter JM, Mullin K, Petersen CA. Transplacental transmission of Leishmania infantum as a means for continued disease incidence in North America. PLoS Negl Trop Dis. 2011 Apr 4/12/2011; 5(4): e1019. PMID: 21532741, PMCID: PMC3075227, DOI: 10.1371/journal.pntd.0001019, ISSN: 1935-2735.

Boggiatto PM, Ramer-Tait AE, Metz K, Kramer EE, Gibson-Corley K, Mullin K, Hostetter JM, Gallup JM, Jones DE, Petersen CA. Immunologic indicators of clinical progression during canine Leishmania infantum infection. Clin Vaccine Immunol [print-electronic]. 2010 Feb; 17(2): 267-73. PMID: 20032217, PMCID: PMC2815526, PII: CVI.00456-09, DOI: 10.1128/CVI.00456-09, ISSN: 1556-679X.

Gibson-Corley KN, Boggiatto PM, Mukbel RM, Petersen CA, Jones DE. A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis. Int J Parasitol [print-electronic]. 2010 Feb; 40(2): 157-61. PMID: 20004204, PMCID: PMC2814795, PII: S0020-7519(09)00429-9, DOI: 10.1016/j.ijpara.2009.11.010, ISSN: 1879-0135.

Boggiatto PM, Jie F, Ghosh M, Gibson-Corley KN, Ramer-Tait AE, Jones DE, Petersen CA. Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK. Am J Pathol [print-electronic]. 2009 May; 174(5): 1818-26. PMID: 19349356, PMCID: PMC2671270, PII: S0002-9440(10)61039-5, DOI: 10.2353/ajpath.2009.080905, ISSN: 1525-2191.

Gibson-Corley KN, Hostetter JM, Hostetter SJ, Mullin K, Ramer-Tait AE, Boggiatto PM, Petersen CA. Disseminated Leishmania infantum infection in two sibling foxhounds due to possible vertical transmission. Can Vet J. 2008 Oct; 49(10): 1005-8. PMID: 19119370, PMCID: PMC2553493, ISSN: 0008-5286.