Yacob G. Tedla, Ph.D.

Assistant Professor

Faculty Appointments
Assistant Professor of Medicine
Ph.D., Epidemiology, University of Wisconsin, Madison, WisconsinM.S., Epidemiology, University of Wisconsin, Madison, Wisconsin
Research Description
Dr. Tedla’s research interest focuses on vascular structural and functional abnormalities and their effect on cardiovascular events. He also conducts research to understand determinants of racial disparities in cardiovascular diseases. His recent works identified new risk factors for arterial stiffness progression and blood pressure variability and the impact of different blood pressure components on cardiovascular events. Dr. Tedla is currently funded by the National Institute of Health (K01 grant) to evaluate provider compliance to hypertension treatment guideline and patients’ blood pressure trajectory and by the BMS/Pfizer alliance to explore racial disparity in the utilization of anticoagulants and the risk of stroke and major bleeding in patients with atrial fibrillation. Dr. Tedla uses data from multi-center epidemiologic cohort studies and electronic health records to conduct his research, leveraging robust epidemiologic methods and bioinformatics techniques. To facilitate his research, Dr. Tedla collaborates with an interdisciplinary team consisting of epidemiologists, public health experts, biostatisticians, cardiologists, internists, and others. His research career goal is to develop a collaborative research program to promote cardiovascular health and reduce disparity in cardiovascular diseases.
Research Keywords
Cardiovascular epidemiology, cardiovascular diseases, racial disparity, hypertension, arterial stiffness, blood pressure variability, epidemiologic methods
Tedla YG, Gepner A, Stein JH, Delaney JA, Liu CY, Greenland P. Optimal lifestyle behaviors and 10-year progression of arterial stiffness: The multi-ethnic study of atherosclerosis. J Clin Hypertens (Greenwich) [print-electronic]. 2022 Feb 2/8/2022; PMID: 35132757, DOI: 10.1111/jch.14430, ISSN: 1751-7176.

Tedla YG, Gepner A, Stein JH, Delaney JA, Liu CY, Greenland P, et al. Optimal lifestyle behaviors and 10-year progression of arterial stiffness: The multi-ethnic study of atherosclerosis. J Clin Hypertens. 2022 Feb; doi: 10.1111/jch.14430. Epub ahead of print. PMID: 35132757.

Pewowaruk RJ, Tedla Y, Korcarz CE, Tattersall MC, Stein JH, Chesler NC, Gepner AD. Carotid Artery Stiffening With Aging: Structural Versus Load-Dependent Mechanisms in MESA (the Multi-Ethnic Study of Atherosclerosis). Hypertension. 2022 Jan; 79(1): 150-8.

Pewowaruk RJ, Korcarz C, Tedla Y, Burke G, Greenland P, Wu C, Gepner AD. Carotid Artery Stiffness Mechanisms Associated With Cardiovascular Disease Events and Incident Hypertension: the MESA. Hypertension. 2022 Jan; doi: 10.1161/HYPERTENSIONAHA.121.18772. Epub ahead of print. PMID: 35021857.

Yu J, Wang AA, Zimmerman LP, Deng Y, Vu TT, Tedla YG, Soulakis ND, Ahmad FS, Kho AN. A Cohort Analysis of Statin Treatment Patterns Among Small-Sized Primary Care Practices. J Gen Intern Med. 2022 Jan; doi: 10.1007/s11606-021-07191-9. Epub ahead of print. PMID: 34997391.

Tedla YG, Pummannee T, Lauver DR. Cardiovascular Patients' Adherence to the Exercise Component of a Cardiac Rehabilitation Program: Role of Patients’ Perceived Autonomy Support, Motivation, and Competence. J Phys Med Rehabil Disabil. 2021 Oct; 7(2).

Pummanee T, Chunuan S, Tedla YG, Purinthrapibal S, Chupon N. Developing and evaluating the Teen-Strong life skills programme in Southern Thailand. Health Promot Int [print-electronic]. 2021 Sep 9/12/2021; PMID: 34510197, PII: 6369162, DOI: 10.1093/heapro/daab147, ISSN: 1460-2245.

Moin A, Mohanty N, Tedla YG, Carroll AJ, Padilla R, Langman CB, Smith JD. Under-recognition of pediatric hypertension diagnosis: Examination of 1 year of visits to community health centers. J Clin Hypertens (Greenwich) [print-electronic]. 2021 Feb; 23(2): 257-64. PMID: 33373088, DOI: 10.1111/jch.14148, ISSN: 1751-7176.

Deng Y, Pacheco J, Chung A, Mao C, Smith J, Zhao J, Wei W, Barnado A, Weng C, Liu C, Cordon A, Yu J, Tedla YG, Kho A, Ramsey-Goldman R, Walunas T, Luo Y. Natural language processing to identify lupus nephritis phenotype in electronic health records. Arxiv.org. 2021; arXiv preprint arXiv:2112.10821.

Tedla YG, Schwartz SM, Silberman P, Greenland P, Passman RS. Racial Disparity in the Prescription of Anticoagulants and Risk of Stroke and Bleeding in Atrial Fibrillation Patients. J Stroke Cerebrovasc Dis [print-electronic]. 2020 May; 29(5): 104718. PMID: 32122777, PII: S1052-3057(20)30094-X, DOI: 10.1016/j.jstrokecerebrovasdis.2020.104718, ISSN: 1532-8511.

Smith JD, Mohanty N, Davis MM, Knapp AA, Tedla YG, Carroll AJ, Price HE, Villamar JA, Padilla R, Jordan N, Brown CH, Langman CB. Optimizing the implementation of a population panel management intervention in safety-net clinics for pediatric hypertension (The OpTIMISe-Pediatric Hypertension Study). Implement Sci Commun [print-electronic]. 2020; 1(1): 57. PMID: 32835224, PMCID: PMC7386167, PII: 39, DOI: 10.1186/s43058-020-00039-z, ISSN: 2662-2211.

Schwartz SM, Tedla YG, Greenland P, Yadlapati A, Passman RS. Discriminative Ability of CHA2DS2-VASc and HAS-BLED Score in Whites and Nonwhites. Am J Cardiol [print-electronic]. 2019 Jun 6/15/2019; 123(12): 1949-54. PMID: 30979410, PII: S0002-9149(19)30317-0, DOI: 10.1016/j.amjcard.2019.03.020, ISSN: 1879-1913.

Tedla YG, Yano Y, Thyagarajan B, Kalhan R, Viera AJ, Rosenberg S, Greenland P, Carnethon MR. Peak lung function during young adulthood and future long-term blood pressure variability: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Atherosclerosis [print-electronic]. 2018 Aug; 275: 225-31. PMID: 29957459, PMCID: PMC7702294, PII: S0021-9150(18)31128-6, DOI: 10.1016/j.atherosclerosis.2018.06.816, ISSN: 1879-1484.

Lane-Cordova AD, Tedla YG, Carnethon MR, Montag SE, Dude AM, Rasmussen-Torvik LJ. Pre-pregnancy blood pressure and body mass index trajectories and incident hypertensive disorders of pregnancy. Pregnancy Hypertens [print-electronic]. 2018 Jul; 13: 138-40. PMID: 30177041, PII: S2210-7789(17)30518-4, DOI: 10.1016/j.preghy.2018.06.003, ISSN: 2210-7797.

Pummanee T, Tedla YG, Rieschc SK, et al. Barriers to the Quality of Parent-Adolescent Communication in Thailand. International J of Child Dev and Mental H. 2018; 6(1): 88-102.

Yano Y, Reis JP, Levine DA, Bryan RN, Viera AJ, Shimbo D, Tedla YG, Allen NB, Schreiner PJ, Bancks MP, Sidney S, Pletcher MJ, Liu K, Greenland P, Lloyd-Jones DM, Launer LJ. Visit-to-Visit Blood Pressure Variability in Young Adulthood and Hippocampal Volume and Integrity at Middle Age: The CARDIA Study (Coronary Artery Risk Development in Young Adults). Hypertension [print-electronic]. 2017 Dec; 70(6): 1091-8. PMID: 28993449, PMCID: PMC5680098, PII: HYPERTENSIONAHA.117.10144, DOI: 10.1161/HYPERTENSIONAHA.117.10144, ISSN: 1524-4563.

Tedla YG, Bautista LE. Factors associated with false-positive self-reported adherence to antihypertensive drugs. J Hum Hypertens [print-electronic]. 2017 May; 31(5): 320-6. PMID: 27853149, PMCID: PMC6062205, PII: jhh201680, DOI: 10.1038/jhh.2016.80, ISSN: 1476-5527.

Yano Y, Reis JP, Tedla YG, Goff DC, Jacobs DR, Sidney S, Ning H, Liu K, Greenland P, Lloyd-Jones DM. Racial Differences in Associations of Blood Pressure Components in Young Adulthood With Incident Cardiovascular Disease by Middle Age: Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA Cardiol. 2017 Apr 4/1/2017; 2(4): 381-9. PMID: 28199497, PMCID: PMC5470409, PII: 2601764, DOI: 10.1001/jamacardio.2016.5678, ISSN: 2380-6591.

Tedla YG, Gepner AD, Vaidya D, Colangelo L, Stein JH, Liu K, Greenland P. Association between long-term blood pressure control and ten-year progression in carotid arterial stiffness among hypertensive individuals: the multiethnic study of atherosclerosis. J Hypertens. 2017 Apr; 35(4): 862-9. PMID: 28092279, DOI: 10.1097/HJH.0000000000001199, ISSN: 1473-5598.

Tedla YG, Yano Y, Carnethon M, Greenland P. Association Between Long-Term Blood Pressure Variability and 10-Year Progression in Arterial Stiffness: The Multiethnic Study of Atherosclerosis. Hypertension [print-electronic]. 2017 Jan; 69(1): 118-27. PMID: 27849565, PMCID: PMC5145729, PII: HYPERTENSIONAHA.116.08427, DOI: 10.1161/HYPERTENSIONAHA.116.08427, ISSN: 1524-4563.

Gepner AD, Tedla Y, Colangelo LA, Tattersall MC, Korcarz CE, Kaufman JD, Liu K, Burke GL, Shea S, Greenland P, Stein JH. Progression of Carotid Arterial Stiffness With Treatment of Hypertension Over 10 Years: The Multi-Ethnic Study of Atherosclerosis. Hypertension [print-electronic]. 2017 Jan; 69(1): 87-95. PMID: 27849564, PMCID: PMC5145748, PII: HYPERTENSIONAHA.116.08402, DOI: 10.1161/HYPERTENSIONAHA.116.08402, ISSN: 1524-4563.

Tedla YG, Bautista LE. Drug Side Effect Symptoms and Adherence to Antihypertensive Medication. Am J Hypertens [print-electronic]. 2016 Jun; 29(6): 772-9. PMID: 26643686, PMCID: PMC5863783, PII: hpv185, DOI: 10.1093/ajh/hpv185, ISSN: 1941-7225.

Tedla YG, Bautista LE. Response to "Antihypertensive Drug-Related Side Effects: Is it the Unique Indicator for Nonadherence?" [letter]. Am J Hypertens [print-electronic]. 2016 May; 29(5): 663. PMID: 26988420, PMCID: PMC6267937, PII: hpw029, DOI: 10.1093/ajh/hpw029, ISSN: 1941-7225.