Denis Mogilenko, Ph.D.

Assistant Professor
Faculty Appointments
Assistant Professor of Medicine Assistant Professor of Pathology, Microbiology and ImmunologyAssistant Professor of Pathology, Microbiology and Immunology
Ph.D., Institute of Experimental Medicine, St. Petersburg, RussiaM.S., St. Petersburg State University, St. Petersburg, RussiaB.S., St. Petersburg State University, St. Petersburg, Russia
Research Description
Our research focuses on how obesity and aging reshape immune responses and lead to inflammatory diseases and tumor development. Immune cells are sensitive to their metabolic environment, which affects intracellular metabolism and signaling and fine-tune immune functions. We are interested in understanding how metabolic cues regulate communication between immune cells, focusing on dendritic cells and T cells. Our Lab studies how obesity and aging disturb the immune and metabolic balance and lead to excessive inflammation and impaired immune responses. We decode molecular mechanisms that link immune cell metabolism to immune functions by combining experimental and systems immunology approaches.
Research Keywords
Immunology Metabolism Molecular Biology Systems Biology Computational Biology Cancer Biology Obesity Aging Immunometabolism